Other Species / Isoforms
  Tip60 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 4
Tip60 (human) gap -
Tip60 iso2 (human) gap -
Tip60 iso3 (human) __MAEVVsPVPGAGR S6-p
Tip60 (mouse) gap -
Tip60 iso2 (mouse) gap -
Tip60 (rat) gap -
-
gap
0 3
Tip60 (human) gap -
Tip60 iso2 (human) gap -
Tip60 iso3 (human) ADPGVALsPQGEIIE S35-p
Tip60 (mouse) gap -
Tip60 iso2 (mouse) gap -
Tip60 (rat) gap -
K120-ac
TLRFNLPkEREAIPG
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) TLRFNLPkEREAIPG K120-ac
Tip60 iso2 (human) gap -
Tip60 iso3 (human) TLRFNLPKEREAIPG K153
Tip60 (mouse) TLRFNLPKEREAIPG K120
Tip60 iso2 (mouse) gap -
Tip60 (rat) TLRFNLPKEREAIPG K120
K35-ub
LAEILSVkDISGRKL
0 2
Tip60 (human) LAEILSVkDISGRKL K35-ub
Tip60 iso2 (human) LAEILSVKDISGRKL K35
Tip60 iso3 (human) LAEILSVKDISGRKL K68
Tip60 (mouse) LAEILSVKDISGRKL K35
Tip60 iso2 (mouse) LAEILSVKDISGRKL K35
Tip60 (rat) LAEILSVKDISGRKL K35
Y44-p
ISGRKLFyVHYIDFN
Upstream
Downstream
3 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • Abl (human)
Regulatory protein:
  • Abi-1 (human)
  • HP1 alpha (human)
Treatment
  • imatinib
  • ionizing_radiation
  • okadaic_acid
  • trichostatin_A
view more >
Tip60 (human) ISGRKLFyVHYIDFN Y44-p
Tip60 iso2 (human) ISGRKLFYVHYIDFN Y44
Tip60 iso3 (human) ISGRKLFYVHYIDFN Y77
Tip60 (mouse) ISGRKLFYVHYIDFN Y44
Tip60 iso2 (mouse) ISGRKLFYVHYIDFN Y44
Tip60 (rat) ISGRKLFYVHYIDFN Y44
K52-ac
VHYIDFNkRLDEWVT
Upstream
0 5
Treatment
  • vorinostat
Tip60 (human) VHYIDFNkRLDEWVT K52-ac
Tip60 iso2 (human) VHYIDFNKRLDEWVT K52
Tip60 iso3 (human) VHYIDFNKRLDEWVT K85
Tip60 (mouse) VHYIDFNKRLDEWVT K52
Tip60 iso2 (mouse) VHYIDFNKRLDEWVT K52
Tip60 (rat) VHYIDFNKRLDEWVT K52
S86-p
TKNGLPGsRPGsPER
Upstream
Downstream
9 34
Effects on Modified Protein
  • acetylation
  • activity, induced
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, induced
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • CDK1 (human)
  • GSK3B (human)
Putative in vivo kinases:
  • CDK1 (human)
  • GSK3B (human)
Regulatory protein:
  • APP (human)
  • Fe65 (human)
Treatment
  • Akt_inhibitor_IV
  • etoposide
  • metformin
  • rapamycin
  • RO-3306
  • SB216763
  • seliciclib
  • serum_starvation
  • siRNA
  • SNS-032
view more >
Tip60 (human) TKNGLPGsRPGsPER S86-p
Tip60 iso2 (human) TKNGLPGsRPGsPER S86-p
Tip60 iso3 (human) TKNGLPGSRPGSPER S119
Tip60 (mouse) TKNGLPGsRPGsPER S86-p
Tip60 iso2 (mouse) TKNGLPGsRPGsPER S86-p
Tip60 (rat) TKNGLPGsRPGsPER S86-p
S86
TKNGLPGSRPGsPER
1 0
Tip60 (human) TKNGLPGSRPGsPER S86
Tip60 iso2 (human) TKNGLPGSRPGsPER S86
Tip60 iso3 (human) TKNGLPGsRPGSPER S119-gl
Tip60 (mouse) TKNGLPGSRPGsPER S86
Tip60 iso2 (mouse) TKNGLPGSRPGsPER S86
Tip60 (rat) TKNGLPGSRPGsPER S86
S90-p
LPGsRPGsPEREVPA
Upstream
Downstream
6 49
Effects on Modified Protein
  • acetylation
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • transcription, altered
Kinase, in vitro:
  • CDK1 (human)
  • GSK3B (human)
Putative in vivo kinases:
  • CDK1 (human)
  • GSK3B (human)
Regulatory protein:
  • APP (human)
  • Fe65 (human)
Treatment
  • etoposide
  • metformin
  • nocodazole
  • RO-3306
  • seliciclib
  • SNS-032
view more >
Tip60 (human) LPGsRPGsPEREVPA S90-p
Tip60 iso2 (human) LPGsRPGsPEREVKR S90-p
Tip60 iso3 (human) LPGsRPGSPEREVPA S123
Tip60 (mouse) LPGsRPGsPEREVPA S90-p
Tip60 iso2 (mouse) LPGsRPGsPEREVKR S90-p
Tip60 (rat) LPGsRPGsPEREVPA S90-p
K104-ac
ASAQASGkTLPIPVQ
Downstream
1 3
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) ASAQASGkTLPIPVQ K104-ac
Tip60 iso2 (human) gap -
Tip60 iso3 (human) ASAQASGKTLPIPVQ K137
Tip60 (mouse) ASAQASGKTLPIPVQ K104
Tip60 iso2 (mouse) gap -
Tip60 (rat) ASAQASGkTLPIPVQ K104-ac
K148-ac
QPNHRSTkRkVEVVs
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) QPNHRSTkRkVEVVs K148-ac
Tip60 iso2 (human) GsPEREVKRKVEVVs K96
Tip60 iso3 (human) QPNHRSTKRKVEVVS K181
Tip60 (mouse) QPNHRSTKRKVEVVs K148
Tip60 iso2 (mouse) GsPEREVKRKVEVVS K96
Tip60 (rat) QPNHRSTKRKVEVVS K148
K150-ac
NHRSTkRkVEVVsPA
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) NHRSTkRkVEVVsPA K150-ac
Tip60 iso2 (human) PEREVKRKVEVVsPA K98
Tip60 iso3 (human) NHRSTKRKVEVVSPA K183
Tip60 (mouse) NHRSTKRKVEVVsPA K150
Tip60 iso2 (mouse) PEREVKRKVEVVSPA K98
Tip60 (rat) NHRSTKRKVEVVSPA K150
S155-p
kRkVEVVsPAtPVPS
0 10
Tip60 (human) kRkVEVVsPAtPVPS S155-p
Tip60 iso2 (human) KRKVEVVsPAtPVPS S103-p
Tip60 iso3 (human) KRKVEVVSPATPVPS S188
Tip60 (mouse) KRKVEVVsPATPVPS S155-p
Tip60 iso2 (mouse) KRKVEVVSPATPVPS S103
Tip60 (rat) KRKVEVVSPATPVPS S155
T158-p
VEVVsPAtPVPSETA
Upstream
Downstream
3 7
Effects on Modified Protein
  • acetylation
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • P38A (mouse)
  • P38A (no information)
  • P38B (human)
  • P38D (human)
  • P38G (human)
view more >
Putative in vivo kinases:
  • P38A (human)
  • P38D (human)
  • VRK1 (human)
view more >
Regulatory protein:
  • MAPKAPK5 (human)
  • MKK3 (human)
  • MKK6 (human)
  • P38G (human)
view more >
Treatment
  • adriamycin
  • ionizing_radiation
  • SB203580
  • siRNA
  • VE-821
view more >
Tip60 (human) VEVVsPAtPVPSETA T158-p
Tip60 iso2 (human) VEVVsPAtPVPSETA T106-p
Tip60 iso3 (human) VEVVSPATPVPSETA T191
Tip60 (mouse) VEVVsPATPVPSETA T158
Tip60 iso2 (mouse) VEVVSPATPVPSETA T106
Tip60 (rat) VEVVSPATPVPSETA T158
K187-ac
VAAQPGRkRksNCLG
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) VAAQPGRkRksNCLG K187-ac
Tip60 iso2 (human) VAAQPGRKRKSNCLG K135
Tip60 iso3 (human) VAAQPGRKRKSNCLG K220
Tip60 (mouse) VAAQPGRKRKsNCLG K187
Tip60 iso2 (mouse) VAAQPGRKRKSNCLG K135
Tip60 (rat) VAAQPGRKRKSNCLG K187
K189-ac
AQPGRkRksNCLGtD
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
Tip60 (human) AQPGRkRksNCLGtD K189-ac
Tip60 iso2 (human) AQPGRKRKSNCLGTD K137
Tip60 iso3 (human) AQPGRKRKSNCLGTD K222
Tip60 (mouse) AQPGRKRKsNCLGtD K189
Tip60 iso2 (mouse) AQPGRKRKSNCLGTD K137
Tip60 (rat) AQPGRKRKSNCLGTD K189
S190-p
QPGRkRksNCLGtDE
0 14
Tip60 (human) QPGRkRksNCLGtDE S190-p
Tip60 iso2 (human) QPGRKRKSNCLGTDE S138
Tip60 iso3 (human) QPGRKRKSNCLGTDE S223
Tip60 (mouse) QPGRKRKsNCLGtDE S190-p
Tip60 iso2 (mouse) QPGRKRKSNCLGTDE S138
Tip60 (rat) QPGRKRKSNCLGTDE S190
T195-p
RksNCLGtDEDsQDs
0 9
Tip60 (human) RksNCLGtDEDsQDs T195-p
Tip60 iso2 (human) RKSNCLGTDEDSQDS T143
Tip60 iso3 (human) RKSNCLGTDEDSQDS T228
Tip60 (mouse) RKsNCLGtDEDsQDs T195-p
Tip60 iso2 (mouse) RKSNCLGTDEDSQDS T143
Tip60 (rat) RKSNCLGTDEDSQDS T195
S199-p
CLGtDEDsQDssDGI
Upstream
Downstream
1 27
Effects on Modified Protein
  • acetylation
  • enzymatic activity, induced
  • protein stabilization
Regulatory protein:
  • VRK1 (human)
Treatment
  • adriamycin
  • caffeine
  • JNK_inhibitor_VIII
  • KU-55933
  • metformin
  • NU7026
  • SB203580
  • seliciclib
  • VE-821
view more >
Tip60 (human) CLGtDEDsQDssDGI S199-p
Tip60 iso2 (human) CLGTDEDSQDSSDGI S147
Tip60 iso3 (human) CLGTDEDSQDSSDGI S232
Tip60 (mouse) CLGtDEDsQDssDGI S199-p
Tip60 iso2 (mouse) CLGTDEDSQDSSDGI S147
Tip60 (rat) CLGTDEDSQDSSDGI S199
S202-p
tDEDsQDssDGIPSA
0 10
Tip60 (human) tDEDsQDssDGIPSA S202-p
Tip60 iso2 (human) TDEDSQDSSDGIPSA S150
Tip60 iso3 (human) TDEDSQDSSDGIPSA S235
Tip60 (mouse) tDEDsQDssDGIPSA S202-p
Tip60 iso2 (mouse) TDEDSQDSSDGIPSA S150
Tip60 (rat) TDEDSQDSSDGIPSA S202
S203-p
DEDsQDssDGIPSAP
0 5
Tip60 (human) DEDsQDssDGIPSAP S203-p
Tip60 iso2 (human) DEDSQDSSDGIPSAP S151
Tip60 iso3 (human) DEDSQDSSDGIPSAP S236
Tip60 (mouse) DEDsQDssDGIPSAP S203-p
Tip60 iso2 (mouse) DEDSQDSSDGIPSAP S151
Tip60 (rat) DEDSQDSSDGIPSAP S203
T227-p
RSHDDIVtRMkNIEC
0 1
Tip60 (human) RSHDDIVtRMkNIEC T227-p
Tip60 iso2 (human) RSHDDIVTRMKNIEC T175
Tip60 iso3 (human) RSHDDIVTRMKNIEC T260
Tip60 (mouse) RSHDDIVTRMKNIEC T227
Tip60 iso2 (mouse) RSHDDIVTRMKNIEC T175
Tip60 (rat) RSHDDIVTRMKNIEC T227
K230-ub
DDIVtRMkNIECIEL
0 2
Tip60 (human) DDIVtRMkNIECIEL K230-ub
Tip60 iso2 (human) DDIVTRMKNIECIEL K178
Tip60 iso3 (human) DDIVTRMKNIECIEL K263
Tip60 (mouse) DDIVTRMKNIECIEL K230
Tip60 iso2 (mouse) DDIVTRMKNIECIEL K178
Tip60 (rat) DDIVTRMKNIECIEL K230
K268-ac
YLCEFCLkYGRSLkC
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
Treatment
  • siRNA
Tip60 (human) YLCEFCLkYGRSLkC K268-ac
Tip60 iso2 (human) YLCEFCLKYGRSLKC K216
Tip60 iso3 (human) YLCEFCLKYGRSLKC K301
Tip60 (mouse) YLCEFCLKYGRSLKC K268
Tip60 iso2 (mouse) YLCEFCLKYGRSLKC K216
Tip60 (rat) YLCEFCLKYGRSLKC K268
K274-ub
LkYGRSLkCLQRHLt
0 1
Tip60 (human) LkYGRSLkCLQRHLt K274-ub
Tip60 iso2 (human) LKYGRSLKCLQRHLT K222
Tip60 iso3 (human) LKYGRSLKCLQRHLT K307
Tip60 (mouse) LKYGRSLKCLQRHLT K274
Tip60 iso2 (mouse) LKYGRSLKCLQRHLT K222
Tip60 (rat) LKYGRSLKCLQRHLT K274
T281-p
kCLQRHLtkCDLRHP
0 1
Tip60 (human) kCLQRHLtkCDLRHP T281-p
Tip60 iso2 (human) KCLQRHLTKCDLRHP T229
Tip60 iso3 (human) KCLQRHLTKCDLRHP T314
Tip60 (mouse) KCLQRHLTKCDLRHP T281
Tip60 iso2 (mouse) KCLQRHLTKCDLRHP T229
Tip60 (rat) CLQRHLTKCDLRHPP K282
K282-ac
CLQRHLtkCDLRHPP
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
Treatment
  • siRNA
Tip60 (human) CLQRHLtkCDLRHPP K282-ac
Tip60 iso2 (human) CLQRHLTKCDLRHPP K230
Tip60 iso3 (human) CLQRHLTKCDLRHPP K315
Tip60 (mouse) CLQRHLTKCDLRHPP K282
Tip60 iso2 (mouse) CLQRHLTKCDLRHPP K230
Tip60 (rat) CLQRHLTKCDLRHPP K282
K282-ub
CLQRHLtkCDLRHPP
0 2
Tip60 (human) CLQRHLtkCDLRHPP K282-ub
Tip60 iso2 (human) CLQRHLTKCDLRHPP K230
Tip60 iso3 (human) CLQRHLTKCDLRHPP K315
Tip60 (mouse) CLQRHLTKCDLRHPP K282
Tip60 iso2 (mouse) CLQRHLTKCDLRHPP K230
Tip60 (rat) CLQRHLTKCDLRHPP K282
Y294-p
HPPGNEIyRkGTISF
Upstream
Downstream
1 0
Effects on Modified Protein
  • acetylation
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
Kinase, in vitro:
  • Abl (human)
Putative in vivo kinases:
  • Abl (human)
Tip60 (human) HPPGNEIyRkGTISF Y294-p
Tip60 iso2 (human) HPPGNEIYRKGTISF Y242
Tip60 iso3 (human) HPPGNEIYRKGTISF Y327
Tip60 (mouse) HPPGNEIYRKGTISF Y294
Tip60 iso2 (mouse) HPPGNEIYRKGTISF Y242
Tip60 (rat) HPPGNEIYRKGTISF Y294
K296-ub
PGNEIyRkGTISFFE
0 1
Tip60 (human) PGNEIyRkGTISFFE K296-ub
Tip60 iso2 (human) PGNEIYRKGTISFFE K244
Tip60 iso3 (human) PGNEIYRKGTISFFE K329
Tip60 (mouse) PGNEIYRKGTISFFE K296
Tip60 iso2 (mouse) PGNEIYRKGTISFFE K244
Tip60 (rat) PGNEIYRKGTISFFE K296
K310-ub
EIDGRKNkSYSQNLC
0 2
Tip60 (human) EIDGRKNkSYSQNLC K310-ub
Tip60 iso2 (human) EIDGRKNKSYSQNLC K258
Tip60 iso3 (human) EIDGRKNKSYSQNLC K343
Tip60 (mouse) EIDGRKNKSYSQNLC K310
Tip60 iso2 (mouse) EIDGRKNKSYSQNLC K258
Tip60 (rat) EIDGRKNKSYSQNLC K310
K327-ac
AKCFLDHkTLYYDTD
0 3
Tip60 (human) AKCFLDHkTLYYDTD K327-ac
Tip60 iso2 (human) AKCFLDHKTLYYDTD K275
Tip60 iso3 (human) AKCFLDHKTLYYDTD K360
Tip60 (mouse) AKCFLDHKTLYYDTD K327
Tip60 iso2 (mouse) AKCFLDHKTLYYDTD K275
Tip60 (rat) AKCFLDHKTLYYDTD K327
K404-ub
GKTGTPEkPLSDLGL
0 1
Tip60 (human) GKTGTPEkPLSDLGL K404-ub
Tip60 iso2 (human) GKTGTPEKPLSDLGL K352
Tip60 iso3 (human) GKTGTPEKPLSDLGL K437
Tip60 (mouse) GKTGTPEKPLSDLGL K404
Tip60 iso2 (mouse) GKTGTPEKPLSDLGL K352
Tip60 (rat) GKTGTPEKPLSDLGL K404
K430-sm
LEILMGLksESGERP
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, inhibited
  • carcinogenesis, induced
Treatment
  • siRNA
  • UV
Tip60 (human) LEILMGLksESGERP K430-sm
Tip60 iso2 (human) LEILMGLKSESGERP K378
Tip60 iso3 (human) LEILMGLKSESGERP K463
Tip60 (mouse) LEILMGLKSESGERP K430
Tip60 iso2 (mouse) LEILMGLKSESGERP K378
Tip60 (rat) LEILMGLKSESGERP K430
S431-p
EILMGLksESGERPQ
0 1
Tip60 (human) EILMGLksESGERPQ S431-p
Tip60 iso2 (human) EILMGLKSESGERPQ S379
Tip60 iso3 (human) EILMGLKSESGERPQ S464
Tip60 (mouse) EILMGLKSESGERPQ S431
Tip60 iso2 (mouse) EILMGLKSESGERPQ S379
Tip60 (rat) EILMGLKSESGERPQ S431
K451-ub
ISEITSIkKEDVIST
0 1
Tip60 (human) ISEITSIkKEDVIST K451-ub
Tip60 iso2 (human) ISEITSIKKEDVIST K399
Tip60 iso3 (human) ISEITSIKKEDVIST K484
Tip60 (mouse) ISEITSIKKEDVIST K451
Tip60 iso2 (mouse) ISEITSIKKEDVIST K399
Tip60 (rat) ISEITSIKKEDVIST K451
K451-sm
ISEITSIkKEDVIST
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
Effects on Biological Processes:
  • DNA repair, induced
Treatment
  • UV
Tip60 (human) ISEITSIkKEDVIST K451-sm
Tip60 iso2 (human) ISEITSIKKEDVIST K399
Tip60 iso3 (human) ISEITSIKKEDVIST K484
Tip60 (mouse) ISEITSIKKEDVIST K451
Tip60 iso2 (mouse) ISEITSIKKEDVIST K399
Tip60 (rat) ISEITSIKKEDVIST K451
Y472-p
INYYKGQyILTLSED
1 1
Tip60 (human) INYYKGQyILTLSED Y472-p
Tip60 iso2 (human) INYYKGQYILTLSED Y420
Tip60 iso3 (human) INYYKGQYILTLSED Y505
Tip60 (mouse) INYYKGQYILTLSED Y472
Tip60 iso2 (mouse) INYYKGQYILTLSED Y420
Tip60 (rat) INYYKGQYILTLSED Y472
K498-ub
RLLRIDSkCLHFTPk
0 2
Tip60 (human) RLLRIDSkCLHFTPk K498-ub
Tip60 iso2 (human) RLLRIDSKCLHFTPK K446
Tip60 iso3 (human) RLLRIDSKCLHFTPK K531
Tip60 (mouse) RLLRIDSKCLHFTPK K498
Tip60 iso2 (mouse) RLLRIDSKCLHFTPK K446
Tip60 (rat) RLLRIDSKCLHFTPK K498
K505-ub
kCLHFTPkDWSKRGK
0 1
Tip60 (human) kCLHFTPkDWSKRGK K505-ub
Tip60 iso2 (human) KCLHFTPKDWSKRGK K453
Tip60 iso3 (human) KCLHFTPKDWSKRGK K538
Tip60 (mouse) KCLHFTPKDWSKRGK K505
Tip60 iso2 (mouse) KCLHFTPKDWSKRGK K453
Tip60 (rat) KCLHFTPKDWSKRGK K505