Other Species / Isoforms
  IKKG (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S8-p
MNRHLWKsQLCEMVQ
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
IKKG (human) MNRHLWKsQLCEMVQ S8-p
IKKG iso2 (human) MNRHLWKSQLCEMVQ S76
IKKG (mouse) MNKHPWKNQLSEMVQ N8
IKKG (rat) MSRHLWKNQLSEMVQ N8
S17-p
LCEMVQPsGGPAADQ
Upstream
Downstream
1 3
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
IKKG (human) LCEMVQPsGGPAADQ S17-p
IKKG iso2 (human) LCEMVQPSGGPAADQ S85
IKKG (mouse) LSEMVQPSGGPAEDQ S17
IKKG (rat) LSEMVQPSGGPAEDQ S17
S31-p
QDVLGEEsPLGKPAM
Upstream
Downstream
2 10
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
  • IKKB (human)
IKKG (human) QDVLGEEsPLGKPAM S31-p
IKKG iso2 (human) QDVLGEESPLGKPAM S99
IKKG (mouse) QDMLGEESSLGKPAM S31
IKKG (rat) QDMLGEESSLGKPAM S31
S43-p
PAMLHLPsEQGAPEt
Upstream
Downstream
4 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • sumoylation
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • DNAPK (human)
  • GSK3B (human)
  • IKKB (human)
view more >
Putative in vivo kinases:
  • DNAPK (human)
  • IKKB (human)
Treatment
  • ionizing_radiation
  • NU7026
  • siRNA
view more >
IKKG (human) PAMLHLPsEQGAPEt S43-p
IKKG iso2 (human) PAMLHLPSEQGAPET S111
IKKG (mouse) PAMLHLPSEQGTPET S43
IKKG (rat) PAMLHLPSEQGTPET S43
T50-p
sEQGAPEtLQRCLEE
0 1
IKKG (human) sEQGAPEtLQRCLEE T50-p
IKKG iso2 (human) SEQGAPETLQRCLEE T118
IKKG (mouse) SEQGTPETLQRCLEE T50
IKKG (rat) SEQGTPETLQRCLEE T50
S68-p
LRDAIRQsNQILRER
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • IKKB (human)
Treatment
  • ionomycin
  • okadaic_acid
  • phorbol_ester
  • TNF
view more >
IKKG (human) LRDAIRQsNQILRER S68-p
IKKG iso2 (human) LRDAIRQSNQILRER S136
IKKG (mouse) LRDAIRQSNQMLRER S68
IKKG (rat) LRDAIRQSNQMLRER S68
S85-p
ELLHFQAsQREEKEF
Upstream
Downstream
6 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • ubiquitination
Effects on Biological Processes:
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • ATM (mouse)
  • IKKB (human)
Putative in vivo kinases:
  • ATM (mouse)
Regulatory protein:
  • ATM (mouse)
Treatment
  • adriamycin
  • amphidicolin
  • camptothecin
  • etoposide
  • ionizing_radiation
  • wortmannin
view more >
IKKG (human) ELLHFQAsQREEKEF S85-p
IKKG iso2 (human) ELLHFQASQREEKEF S153
IKKG (mouse) ELLHFQVsQREEKEF S85-p
IKKG (rat) ELLHFQVSQREEKEF S85
K111-ub
VERLGLEkLDLKRQk
0 3
IKKG (human) VERLGLEkLDLKRQk K111-ub
IKKG iso2 (human) VERLGLEKLDLKRQK K179
IKKG (mouse) VERLSLEKLDLRSQR K111
IKKG (rat) VERLSLEKLDLRRQR K111
K118-ub
kLDLKRQkEQALREV
0 1
IKKG (human) kLDLKRQkEQALREV K118-ub
IKKG iso2 (human) KLDLKRQKEQALREV K186
IKKG (mouse) KLDLRSQREQALKEL R118
IKKG (rat) KLDLRRQREQALEDL R118
K143-ub
AEDKASVkAQVTSLL
0 2
IKKG (human) AEDKASVkAQVTSLL K143-ub
IKKG iso2 (human) AEDKASVKAQVTSLL K211
IKKG (mouse) AEDKASVKAQVTSLL K143
IKKG (rat) AEDKASVKAQVTSLL K143
K165-ub
SRLEAATkECQALEG
0 2
IKKG (human) SRLEAATkECQALEG K165-ub
IKKG iso2 (human) SRLEAATKECQALEG K233
IKKG (mouse) SRLEAATKDRQALEG K165
IKKG (rat) SRLEAATKERQTLEG K165
S178-p
EGRARAAsEQARQLE
0 1
IKKG (human) EGRARAAsEQARQLE S178-p
IKKG iso2 (human) EGRARAASEQARQLE S246
IKKG (mouse) EGRIRAVSEQVRQLE S178
IKKG (rat) EGRIRAVSEQVRQLE S178
S196-p
EALQQQHsVQVDQLR
0 1
IKKG (human) EALQQQHsVQVDQLR S196-p
IKKG iso2 (human) EALQQQHSVQVDQLR S264
IKKG (mouse) EVLQQQHSVQVDQLR S196
IKKG (rat) EVLQQQHSVQVDQLR S196
S221
RMERQAASEEKRKLA
0 1
IKKG (human) RMERQAASEEKRKLA S221
IKKG iso2 (human) RMERQAASEEKRKLA S289
IKKG (mouse) RMERQAAsEEKRKLA S221-p
IKKG (rat) RMERQAASEEKRKLA S221
K246-ub
QEYDNHIkSSVVGsE
0 1
IKKG (human) QEYDNHIkSSVVGsE K246-ub
IKKG iso2 (human) QEYDNHIKSSVVGSE K314
IKKG (mouse) QDYDSHIKSSKGMQL K246
IKKG (rat) QDYDSHIKSSKGMQL K246
S252-p
IkSSVVGsERkRGMQ
0 1
IKKG (human) IkSSVVGsERkRGMQ S252-p
IKKG iso2 (human) IKSSVVGSERKRGMQ S320
IKKG (mouse) gap -
IKKG (rat) gap -
K255-ac
SVVGsERkRGMQLED
0 1
IKKG (human) SVVGsERkRGMQLED K255-ac
IKKG iso2 (human) SVVGSERKRGMQLED K323
IKKG (mouse) gap -
IKKG (rat) gap -
K255-ub
SVVGsERkRGMQLED
0 2
IKKG (human) SVVGsERkRGMQLED K255-ub
IKKG iso2 (human) SVVGSERKRGMQLED K323
IKKG (mouse) gap -
IKKG (rat) gap -
K264-ub
GMQLEDLkQQLQQAE
0 2
IKKG (human) GMQLEDLkQQLQQAE K264-ub
IKKG iso2 (human) GMQLEDLKQQLQQAE K332
IKKG (mouse) GMQLEDLRQQLQQAE R257
IKKG (rat) GMQLEDLRQQLQQAE R257
K277-ub
AEEALVAkQEVIDkL
Upstream
Downstream
3 3
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Regulatory protein:
  • ATM (human)
  • XIAP (human)
Treatment
  • adriamycin
  • etoposide
  • PD98059
  • siRNA
view more >
IKKG (human) AEEALVAkQEVIDkL K277-ub
IKKG iso2 (human) AEEALVAKQEVIDKL K345
IKKG (mouse) AEEALVAkQELIDKL K270-ub
IKKG (rat) AEEALVAKQELIDKL K270
K277-sm
AEEALVAkQEVIDkL
Upstream
Downstream
6 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, induced
Regulatory protein:
  • ATM (human)
  • Chk1 (human)
Treatment
  • amphidicolin
  • etoposide
  • H2O2
  • siRNA
view more >
IKKG (human) AEEALVAkQEVIDkL K277-sm
IKKG iso2 (human) AEEALVAKQEVIDKL K345
IKKG (mouse) AEEALVAkQELIDKL K270-sm
IKKG (rat) AEEALVAKQELIDKL K270
K283-ub
AkQEVIDkLkEEAEQ
0 2
IKKG (human) AkQEVIDkLkEEAEQ K283-ub
IKKG iso2 (human) AKQEVIDKLKEEAEQ K351
IKKG (mouse) AkQELIDKLkEEAEQ K276
IKKG (rat) AKQELIDKLKEEAEQ K276
K285-ub
QEVIDkLkEEAEQHk
Upstream
Downstream
8 19
Effects on Modified Protein
  • activity, induced
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, inhibited
  • signaling pathway regulation
  • transcription, induced
Regulatory protein:
  • CYLD (human)
  • RIPK2 (human)
Treatment
  • IL-1b
  • TNF
IKKG (human) QEVIDkLkEEAEQHk K285-ub
IKKG iso2 (human) QEVIDKLKEEAEQHK K353
IKKG (mouse) QELIDKLkEEAEQHK K278-ub
IKKG (rat) QELIDKLKEEAEQHK K278
K292-ub
kEEAEQHkIVMEtVP
0 1
IKKG (human) kEEAEQHkIVMEtVP K292-ub
IKKG iso2 (human) KEEAEQHKIVMETVP K360
IKKG (mouse) kEEAEQHKIVMETVP K285
IKKG (rat) KEEAEQHKIVMETVP K285
T297-p
QHkIVMEtVPVLkAQ
Upstream
0 1
Treatment
  • nocodazole
IKKG (human) QHkIVMEtVPVLkAQ T297-p
IKKG iso2 (human) QHKIVMETVPVLKAQ T365
IKKG (mouse) QHKIVMETVPVLKAQ T290
IKKG (rat) QHKIVMETVPVLKAQ T290
Y308-p
LkAQADIykADFQAE
0 1
IKKG (human) LkAQADIykADFQAE Y308-p
IKKG iso2 (human) LKAQADIYKADFQAE Y376
IKKG (mouse) LKAQADIYkADFQAE Y301
IKKG (rat) LKAQADIYKADFQAE Y301
K309-ub
kAQADIykADFQAER
Upstream
Downstream
7 9
Effects on Modified Protein
  • intracellular localization
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, inhibited
  • signaling pathway regulation
  • transcription, induced
Regulatory protein:
  • ATM (human)
  • TRIM37 (human)
  • XIAP (human)
view more >
Treatment
  • adriamycin
  • etoposide
  • IL-1b
  • PD98059
  • peptide
  • siRNA
  • TNF
view more >
IKKG (human) kAQADIykADFQAER K309-ub
IKKG iso2 (human) KAQADIYKADFQAER K377
IKKG (mouse) KAQADIYkADFQAER K302-ub
IKKG (rat) KAQADIYKADFQAER K302
K309-sm
kAQADIykADFQAER
Upstream
Downstream
5 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, induced
Regulatory protein:
  • ATM (human)
  • Chk1 (human)
Treatment
  • amphidicolin
  • etoposide
  • H2O2
  • siRNA
view more >
IKKG (human) kAQADIykADFQAER K309-sm
IKKG iso2 (human) KAQADIYKADFQAER K377
IKKG (mouse) KAQADIYkADFQAER K302-sm
IKKG (rat) KAQADIYKADFQAER K302
K321-ub
AERQAREkLAEkkEL
Downstream
3 1
Effects on Biological Processes:
  • signaling pathway regulation
IKKG (human) AERQAREkLAEkkEL K321-ub
IKKG iso2 (human) AERQAREKLAEKKEL K389
IKKG (mouse) AERHAREkLVEkkEY K314-ub
IKKG (rat) AERHAREKLVERKEL K314
K325-ub
AREkLAEkkELLQEQ
Downstream
3 1
Effects on Biological Processes:
  • signaling pathway regulation
IKKG (human) AREkLAEkkELLQEQ K325-ub
IKKG iso2 (human) AREKLAEKKELLQEQ K393
IKKG (mouse) AREkLVEkkEYLQEQ K318-ub
IKKG (rat) AREKLVERKELLQEQ R318
K326-ub
REkLAEkkELLQEQL
Downstream
3 2
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • signaling pathway regulation
IKKG (human) REkLAEkkELLQEQL K326-ub
IKKG iso2 (human) REKLAEKKELLQEQL K394
IKKG (mouse) REkLVEkkEYLQEQL K319-ub
IKKG (rat) REKLVERKELLQEQL K319
K342-ub
QLQREYSkLkASCQE
1 1
IKKG (human) QLQREYSkLkASCQE K342-ub
IKKG iso2 (human) QLQREYSKLKASCQE K410
IKKG (mouse) QLQREFNKLkVGCHE K335
IKKG (rat) QLQREFNKLKVGCHE K335
K344-ub
QREYSkLkASCQESA
1 16
IKKG (human) QREYSkLkASCQESA K344-ub
IKKG iso2 (human) QREYSKLKASCQESA K412
IKKG (mouse) QREFNKLkVGCHEsA K337-ub
IKKG (rat) QREFNKLKVGCHESA K337
S350
LkASCQESARIEDMR
0 1
IKKG (human) LkASCQESARIEDMR S350
IKKG iso2 (human) LKASCQESARIEDMR S418
IKKG (mouse) LkVGCHEsARIEDMR S343-p
IKKG (rat) LKVGCHESARIEDMR S343
K358-ub
ARIEDMRkRHVEVSQ
0 1
IKKG (human) ARIEDMRkRHVEVSQ K358-ub
IKKG iso2 (human) ARIEDMRKRHVEVSQ K426
IKKG (mouse) ARIEDMRKRHVETPQ K351
IKKG (rat) ARIEDMRKRHVETSQ K351
Y374-p
PLPPAPAyLssPLAL
Upstream
Downstream
1 12
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
Putative in vivo kinases:
  • FGR (human)
  • Fyn (human)
  • LYN (human)
  • Src (human)
view more >
Treatment
  • TNF
IKKG (human) PLPPAPAyLssPLAL Y374-p
IKKG iso2 (human) PLPPAPAYLSSPLAL Y442
IKKG (mouse) PLLPAPAHHsFHLAL H367
IKKG (rat) PLLPAPAHHSFHLAL H367
S376-p
PPAPAyLssPLALPs
Upstream
5 8
IKKG (human)
S376-p
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • delphinidin
IKKG (human) PPAPAyLssPLALPs S376-p
IKKG iso2 (human) PPAPAYLSSPLALPS S444
IKKG (mouse) LPAPAHHsFHLALsN S369-p
IKKG (rat) LPAPAHHSFHLALSN S369
S377-p
PAPAyLssPLALPsQ
Upstream
Downstream
1 58
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
Regulatory protein:
  • FILIP1 (human)
IKKG (human) PAPAyLssPLALPsQ S377-p
IKKG iso2 (human) PAPAYLSSPLALPSQ S445
IKKG (mouse) PAPAHHsFHLALsNQ F370
IKKG (rat) PAPAHHSFHLALSNQ F370
P382
LssPLALPsQRRsPP
1 0
IKKG (human) LssPLALPsQRRsPP P382
IKKG iso2 (human) LSSPLALPSQRRSPP P450
IKKG (mouse) HsFHLALsNQRRsPP S375-p
IKKG (rat) HSFHLALSNQRRSPP S375
S383-p
ssPLALPsQRRsPPE
Upstream
0 5
Treatment
  • nocodazole
IKKG (human) ssPLALPsQRRsPPE S383-p
IKKG iso2 (human) SSPLALPSQRRSPPE S451
IKKG (mouse) sFHLALsNQRRsPPE N376
IKKG (rat) SFHLALSNQRRSPPE N376
S387-p
ALPsQRRsPPEEPPD
1 27
IKKG (human) ALPsQRRsPPEEPPD S387-p
IKKG iso2 (human) ALPSQRRSPPEEPPD S455
IKKG (mouse) ALsNQRRsPPEEPPD S380-p
IKKG (rat) ALSNQRRSPPEEPPD S380
K399-ub
PPDFCCPkCQYQAPD
Upstream
Downstream
6 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
Regulatory protein:
  • Bcl-10 (human)
  • CARD11 (human)
  • MALT1 (human)
view more >
Treatment
  • ionomycin
  • phorbol_ester
  • siRNA
view more >
IKKG (human) PPDFCCPkCQYQAPD K399-ub
IKKG iso2 (human) PPDFCCPKCQYQAPD K467
IKKG (mouse) PPDFCCPkCQYQAPD K392-ub
IKKG (rat) PPDFCCPKCQYQAPD K392
K302-ub
MEtVPVLkAQADIyk
0 1
IKKG (human) MEtVPVLkAQADIyk K302-ub
IKKG iso2 (human) METVPVLKAQADIYK K370
IKKG (mouse) METVPVLKAQADIYk K295
IKKG (rat) METVPVLKAQADIYK K295