Other Species / Isoforms
  p70S6K (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S40
DQPEDAGSEDELEEG
2 7
p70S6K (human) DQPEDAGsEDELEEG S40-p
p70S6K iso2 (human) DQPEDAGSEDELEEG S17
p70S6K (mouse) DQPEDAGSEDELEEG S40
p70S6K (rat) DQPEDAGsEDELEEG S40-p
p70S6K iso2 (rat) DQPEDAGsEDELEEG S17-p
p70S6K (fruit fly) IELDDVDLEPELCIN L40
S53
EGGQLNESMDHGGVG
1 0
p70S6K (human) EGGQLNEsMDHGGVG S53-p
p70S6K iso2 (human) EGGQLNESMDHGGVG S30
p70S6K (mouse) EGGQLNESMDHGGVG S53
p70S6K (rat) EGGQLNESMDHGGVG S53
p70S6K iso2 (rat) EGGQLNESMDHGGVG S30
p70S6K (fruit fly) PELCINLHQDTEGQE H49
Y62
DHGGVGPYELGMEHC
1 0
p70S6K (human) DHGGVGPYELGMEHC Y62
p70S6K iso2 (human) DHGGVGPYELGMEHC Y39
p70S6K (mouse) DHGGVGPYELGMEHC Y62
p70S6K (rat) DHGGVGPyELGMEHC Y62-p
p70S6K iso2 (rat) DHGGVGPYELGMEHC Y39
p70S6K (fruit fly) gap -
K85
SVNRGPEKIRPECFE
0 1
p70S6K (human) SVNRGPEkIRPECFE K85-ub
p70S6K iso2 (human) SVNRGPEKIRPECFE K62
p70S6K (mouse) SVNRGPEKIRPECFE K85
p70S6K (rat) SVNRGPEKIRPECFE K85
p70S6K iso2 (rat) SVNRGPEKIRPECFE K62
p70S6K (fruit fly) NVNPGKIKLGPKDFE K71
K104-ub
LGKGGYGkVFQVRKV
0 3
p70S6K (human) LGKGGYGkVFQVRKV K104-ub
p70S6K iso2 (human) LGKGGYGKVFQVRKV K81
p70S6K (mouse) LGKGGYGkVFQVRKV K104-ub
p70S6K (rat) LGKGGYGKVFQVRKV K104
p70S6K iso2 (rat) LGKGGYGKVFQVRKV K81
p70S6K (fruit fly) LGKGGYGKVFQVRKT K90
K118
VTGANTGKIFAMkVL
0 1
p70S6K (human) VTGANTGkIFAMKVL K118-ub
p70S6K iso2 (human) VTGANTGKIFAMKVL K95
p70S6K (mouse) VTGANTGKIFAMkVL K118
p70S6K (rat) VTGANTGKIFAMKVL K118
p70S6K iso2 (rat) VTGANTGKIFAMKVL K95
p70S6K (fruit fly) TAGRDANKYFAMKVL K104
K123-ac
TGKIFAMkVLkKAMI
0 1
p70S6K (human) TGkIFAMKVLKKAMI K123
p70S6K iso2 (human) TGKIFAMKVLKKAMI K100
p70S6K (mouse) TGKIFAMkVLkKAMI K123-ac
p70S6K (rat) TGKIFAMKVLKKAMI K123
p70S6K iso2 (rat) TGKIFAMKVLKKAMI K100
p70S6K (fruit fly) ANKYFAMKVLKKASI K109
K126-ac
IFAMkVLkKAMIVRN
0 1
p70S6K (human) IFAMKVLKKAMIVRN K126
p70S6K iso2 (human) IFAMKVLKKAMIVRN K103
p70S6K (mouse) IFAMkVLkKAMIVRN K126-ac
p70S6K (rat) IFAMKVLKKAMIVRN K126
p70S6K iso2 (rat) IFAMKVLKKAMIVRN K103
p70S6K (fruit fly) YFAMKVLKKASIVTN K112
T140-p
NAKDTAHtKAERNIL
Upstream
0 1
Treatment
  • refeeding
p70S6K (human) NAKDTAHTKAERNIL T140
p70S6K iso2 (human) NAKDTAHTKAERNIL T117
p70S6K (mouse) NAKDTAHtKAERNIL T140-p
p70S6K (rat) NAKDTAHTKAERNIL T140
p70S6K iso2 (rat) NAKDTAHTKAERNIL T117
p70S6K (fruit fly) NQKDTAHTRAERNIL T126
R217-m1
HQKGIIYrDLKPENI
0 2
p70S6K (human) HQKGIIYRDLKPENI R217
p70S6K iso2 (human) HQKGIIYRDLKPENI R194
p70S6K (mouse) HQKGIIYrDLKPENI R217-m1
p70S6K (rat) HQKGIIYRDLKPENI R217
p70S6K iso2 (rat) HQKGIIYRDLKPENI R194
p70S6K (fruit fly) HKLGIIYRDLKPENI R203
S243-p
DFGLCKEsIHDGtVt
0 6
p70S6K (human) DFGLCKEsIHDGtVt S243-p
p70S6K iso2 (human) DFGLCKESIHDGTVT S220
p70S6K (mouse) DFGLCKEsIHDGtVt S243-p
p70S6K (rat) DFGLCKESIHDGTVT S243
p70S6K iso2 (rat) DFGLCKESIHDGTVT S220
p70S6K (fruit fly) DFGLCKEHIQEGIVT H229
T248-p
KEsIHDGtVtHtFCG
0 6
p70S6K (human) KEsIHDGtVtHtFCG T248-p
p70S6K iso2 (human) KESIHDGTVTHtFCG T225
p70S6K (mouse) KEsIHDGtVtHtFCG T248-p
p70S6K (rat) KESIHDGTVTHtFCG T248
p70S6K iso2 (rat) KESIHDGTVTHTFCG T225
p70S6K (fruit fly) KEHIQEGIVTHTFCG I234
T250-p
sIHDGtVtHtFCGtI
0 12
p70S6K (human) sIHDGtVtHtFCGtI T250-p
p70S6K iso2 (human) SIHDGTVTHtFCGTI T227
p70S6K (mouse) sIHDGtVtHtFCGtI T250-p
p70S6K (rat) SIHDGTVTHtFCGTI T250
p70S6K iso2 (rat) SIHDGTVTHTFCGTI T227
p70S6K (fruit fly) HIQEGIVTHTFCGTI T236
T252-p
HDGtVtHtFCGtIEY
Upstream
35 19
Regulatory protein:
  • mTOR (mouse)
  • PDK1 (human)
  • PDK1 (mouse)
  • RICTOR (mouse)
view more >
Treatment
  • insulin
  • LPS
  • meal feeding
  • rapamycin
  • troglitazone
  • wortmannin
view more >
p70S6K (human) HDGtVtHtFCGtIEY T252-p
p70S6K iso2 (human) HDGTVTHtFCGTIEY T229-p
p70S6K (mouse) HDGtVtHtFCGtIEY T252-p
p70S6K (rat) HDGTVTHtFCGTIEY T252-p
p70S6K iso2 (rat) HDGTVTHTFCGTIEY T229
p70S6K (fruit fly) QEGIVTHTFCGTIEY T238
T256-p
VtHtFCGtIEYMAPE
0 6
p70S6K (human) VtHtFCGtIEYMAPE T256-p
p70S6K iso2 (human) VTHtFCGTIEYMAPE T233
p70S6K (mouse) VtHtFCGtIEYMAPE T256-p
p70S6K (rat) VTHtFCGTIEYMAPE T256
p70S6K iso2 (rat) VTHTFCGTIEYMAPE T233
p70S6K (fruit fly) VTHTFCGTIEYMAPE T242
K304
NRKKTIDKILKCKLN
0 3
p70S6K (human) NRKKTIDkILKCKLN K304-ac
p70S6K iso2 (human) NRKKTIDKILKCKLN K281
p70S6K (mouse) NRKKTIDKILKCKLN K304
p70S6K (rat) NRKKTIDkILKCKLN K304-ac
p70S6K iso2 (rat) NRKKTIDKILKCKLN K281
p70S6K (fruit fly) NRKKTIETILKAKLN T290
K364
WEELLARKVEPPFKP
0 1
p70S6K (human) WEELLARkVEPPFkP K364-ub
p70S6K iso2 (human) WEELLARKVEPPFKP K341
p70S6K (mouse) WEELLARKVEPPFKP K364
p70S6K (rat) WEELLARKVEPPFKP K364
p70S6K iso2 (rat) WEELLARKVEPPFKP K341
p70S6K (fruit fly) WDDVLARRLEPPIKP R350
K370
RKVEPPFKPLLQSEE
0 1
p70S6K (human) RkVEPPFkPLLQSEE K370-ub
p70S6K iso2 (human) RKVEPPFKPLLQSEE K347
p70S6K (mouse) RKVEPPFKPLLQSEE K370
p70S6K (rat) RKVEPPFKPLLQSEE K370
p70S6K iso2 (rat) RKVEPPFKPLLQSEE K347
p70S6K (fruit fly) RRLEPPIKPLLRSED K356
T390-p
DSKFTRQtPVDsPDD
Upstream
3 14
Treatment
  • cisplatin
  • etoposide
  • insulin
  • topotecan
view more >
p70S6K (human) DSKFTRQtPVDsPDD T390-p
p70S6K iso2 (human) DSKFTRQTPVDsPDD T367
p70S6K (mouse) DSKFTRQtPVDsPDD T390-p
p70S6K (rat) DSKFTRQTPVDsPDD T390
p70S6K iso2 (rat) DSKFTRQTPVDSPDD T367
p70S6K (fruit fly) DTRFTRQIPVDSPDD I376
S394-p
TRQtPVDsPDDSTLS
Upstream
17 14
p70S6K (human)
S394-p
p70S6K (mouse)
S394-p
p70S6K (rat)
S394-p
Regulatory protein:
  • AMPKA1 (mouse)
  • Cas-L (human)
  • FOXO1A (human)
  • FOXO1A (mouse)
  • FOXO3A (human)
  • FOXO3A (mouse)
  • PDK1 (human)
  • RICTOR (mouse)
  • SESN3 (human)
  • STAT4 (mouse)
view more >
Treatment
  • 4-HT
  • acadesine
  • antigenic stimulation
  • B7
  • fructose
  • glucose
  • H2O2
  • IL-12
  • insulin
  • LY294002
  • rapamycin
  • serum
view more >
p70S6K (human) TRQtPVDsPDDStLS S394-p
p70S6K iso2 (human) TRQTPVDsPDDSTLS S371-p
p70S6K (mouse) TRQtPVDsPDDSTLS S394-p
p70S6K (rat) TRQTPVDsPDDSTLS S394-p
p70S6K iso2 (rat) TRQTPVDSPDDSTLS S371
p70S6K (fruit fly) TRQIPVDSPDDTTLS S380
T399
VDsPDDSTLSESANQ
0 1
p70S6K (human) VDsPDDStLSEsANQ T399-p
p70S6K iso2 (human) VDsPDDSTLSESANQ T376
p70S6K (mouse) VDsPDDSTLSESANQ T399
p70S6K (rat) VDsPDDSTLSESANQ T399
p70S6K iso2 (rat) VDSPDDSTLSESANQ T376
p70S6K (fruit fly) VDSPDDTTLSESANL T385
S403
DDSTLSESANQVFLG
1 2
p70S6K (human) DDStLSEsANQVFLG S403-p
p70S6K iso2 (human) DDSTLSESANQVFLG S380
p70S6K (mouse) DDSTLSESANQVFLG S403
p70S6K (rat) DDSTLSESANQVFLG S403
p70S6K iso2 (rat) DDSTLSESANQVFLG S380
p70S6K (fruit fly) DDTTLSESANLIFQG S389
T412-p
NQVFLGFtYVAPSVL
Upstream
Downstream
473 12
p70S6K (human)
T412-p
p70S6K iso2 (human)
T389-p
p70S6K (mouse)
T412-p
p70S6K (rat)
T412-p
p70S6K iso2 (rat)
T389-p
p70S6K (fruit fly)
T398-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • signaling pathway regulation
  • translation, induced
Kinase, in vitro:
  • mTOR (human)
Putative in vivo kinases:
  • mTOR (human)
  • PIK3C2A (human)
Regulatory protein:
  • 4E-BP1 (mouse)
  • ADRB3 (human)
  • Akt1 (human)
  • Akt1 (mouse)
  • AML3 (mouse)
  • AMPKA1 (human)
  • AMPKA1 (mouse)
  • AMPKA2 (mouse)
  • AMPKB1 (mouse)
  • ASB2 (mouse)
  • Bcl-xL (human)
  • CDK1 (mouse)
  • CPT2 (mouse)
  • DEDD (mouse)
  • DEPDC5 (human)
  • DKK1 (human)
  • DNAPK (mouse)
  • Ezrin (mouse)
  • FAK (human)
  • FKBP12 (mouse)
  • FLCN (human)
  • FNIP1 (human)
  • FOXO1A (mouse)
  • Fyn (mouse)
  • GLUT1 (mouse)
  • GRB10 (human)
  • GRN (mouse)
  • HBP1 (human)
  • HRas (human)
  • IFITM3 (human)
  • IFITM3 (rat)
  • IGF2BP2 (mouse)
  • IKKB (human)
  • IRS1 (human)
  • K17 (mouse)
  • KRas (mouse)
  • LAMTOR1 (mouse)
  • LAMTOR2 (mouse)
  • LKB1 (human)
  • LKB1 (mouse)
  • LST8 (mouse)
  • mAChR M3 (human)
  • MAPKAPK5 (mouse)
  • MFGE8 (human)
  • MKK6 (human)
  • Mnk1 (mouse)
  • Mnk2 (mouse)
  • MTHFD2 (human)
  • mTOR (human)
  • mTOR (mouse)
  • P38A (mouse)
  • P38B (human)
  • P38B (mouse)
  • p53 (mouse)
  • p70S6K (human)
  • PCTP (human)
  • PDK1 (mouse)
  • PIK3CA (human)
  • PIK3R1 (human)
  • PIP4K2C (mouse)
  • PKAR1A (human)
  • PKCI (mouse)
  • PRAS40 iso3 (human)
  • PSEN1 (mouse)
  • PTEN (mouse)
  • PTGER3 (mouse)
  • Raptor (human)
  • Raptor (mouse)
  • Rb (mouse)
  • RHEB (human)
  • RHEB (mouse)
  • RICTOR (human)
  • RICTOR (mouse)
  • ROCK1 (mouse)
  • RRAGA (human)
  • RRAGB (human)
  • RRAGC (human)
  • RRAGC (mouse)
  • RRAGD (human)
  • SESN1 (human)
  • SESN1 (mouse)
  • SESN2 (human)
  • SESN2 (mouse)
  • SGK1 (human)
  • Sin1 (human)
  • Sin1 (mouse)
  • syndecan-4 (mouse)
  • TBC1D1 (mouse)
  • TBK1 (human)
  • THEM2 (human)
  • TSC1 (human)
  • TSC1 (mouse)
  • TSC2 (human)
  • TSC2 (mouse)
  • UBXN2A (human)
  • ULK1 (mouse)
  • USP1 (human)
  • VEGF iso1 (human)
  • Vimentin (human)
view more >
Treatment
  • 1-MT
  • 15d-PGJ2
  • 2-deoxyglucose
  • 991
  • acadesine
  • actinomycin_D
  • adiponectin
  • adriamycin
  • AMDE-1
  • amino_acid_starvation
  • amino_acids
  • anisomycin
  • antibody
  • arsenite
  • AS252424
  • ATP
  • BAPTA-AM
  • butaprost
  • butyrate
  • BX795
  • calorie_restriction
  • calyculin_A
  • cannabidiol
  • carboplatin
  • catalase
  • CC260
  • cell_detachment
  • CNO
  • compound_C
  • culturing_of_cells
  • cycloheximide
  • dexamethasone
  • eccentric contractions
  • EGF
  • exercise
  • fasting
  • formate
  • fructose
  • glucose
  • glucose_starvation
  • H2O2
  • hepatitis C virus expression
  • high-fat diet
  • hypoxia
  • IBMX
  • IC87114
  • IDO5L
  • IFN-gamma
  • IGF-1
  • IL-11
  • IL-2
  • IL-3
  • IL-4
  • imatinib
  • insulin
  • ionomycin
  • ischemia/reperfusion
  • JAK_inhibitor_I
  • KU-0063794
  • L-744,832
  • L-glutamine_withdrawal
  • leptin
  • leucine
  • lithium
  • LPS
  • LY294002
  • meal feeding
  • metformin
  • miRNA
  • MPP+
  • NAC
  • NADPH
  • NBD_peptide
  • nitric_oxide
  • NKH_477
  • norepinephrine
  • NP68
  • okadaic_acid
  • orexin
  • ouabain
  • palbociclib
  • palmitate
  • PD184352
  • PD98059
  • PDGF
  • PGE2
  • PGRN
  • phorbol_ester
  • PI-103
  • PIF
  • PIK90
  • pilocarpine
  • PP242
  • pressure
  • PTX
  • RAD001
  • rapamycin
  • refeeding
  • resatorvid
  • retinoic_acid
  • S961
  • SB202190
  • SB203580
  • SC-514
  • SC-79
  • serum
  • serum_starvation
  • serum_withdrawal
  • siRNA
  • SOD
  • sulprostone
  • TAC
  • tamoxifen
  • TGF-beta
  • thapsigargin
  • TNF
  • Torin1
  • troglitazone
  • U0126
  • UV
  • Wnt
  • Wnt10b
  • Wnt3a
  • wortmannin
view more >
p70S6K (human) NQVFLGFtyVAPsVL T412-p
p70S6K iso2 (human) NQVFLGFtYVAPSVL T389-p
p70S6K (mouse) NQVFLGFtYVAPSVL T412-p
p70S6K (rat) NQVFLGFtYVAPSVL T412-p
p70S6K iso2 (rat) NQVFLGFtYVAPSVL T389-p
p70S6K (fruit fly) NLIFQGFTYVAPSIL T398
Y413
QVFLGFtYVAPSVLE
0 2
p70S6K (human) QVFLGFtyVAPsVLE Y413-p
p70S6K iso2 (human) QVFLGFtYVAPSVLE Y390
p70S6K (mouse) QVFLGFtYVAPSVLE Y413
p70S6K (rat) QVFLGFtYVAPSVLE Y413
p70S6K iso2 (rat) QVFLGFtYVAPSVLE Y390
p70S6K (fruit fly) LIFQGFTYVAPSILE Y399
S417
GFtYVAPSVLESVKE
0 1
p70S6K (human) GFtyVAPsVLEsVKE S417-p
p70S6K iso2 (human) GFtYVAPSVLESVKE S394
p70S6K (mouse) GFtYVAPSVLESVKE S417
p70S6K (rat) GFtYVAPSVLESVKE S417
p70S6K iso2 (rat) GFtYVAPSVLESVKE S394
p70S6K (fruit fly) GFTYVAPSILEDMHR S403
S421
VAPSVLESVKEKFsF
0 2
p70S6K (human) VAPsVLEsVKEkFsF S421-p
p70S6K iso2 (human) VAPSVLESVKEKFSF S398
p70S6K (mouse) VAPSVLESVKEKFsF S421
p70S6K (rat) VAPSVLESVKEKFSF S421
p70S6K iso2 (rat) VAPSVLESVKEKFSF S398
p70S6K (fruit fly) VAPSILEDMHRANRM D407
K425
VLESVKEKFsFEPKI
0 1
p70S6K (human) VLEsVKEkFsFEPKI K425-ub
p70S6K iso2 (human) VLESVKEKFSFEPKI K402
p70S6K (mouse) VLESVKEKFsFEPKI K425
p70S6K (rat) VLESVKEKFSFEPKI K425
p70S6K iso2 (rat) VLESVKEKFSFEPKI K402
p70S6K (fruit fly) gap -
S427-p
ESVKEKFsFEPKIRs
Upstream
5 12
Treatment
  • GSK2334470
  • insulin
  • LY294002
  • MK-2206
  • Torin1
view more >
p70S6K (human) EsVKEkFsFEPKIRs S427-p
p70S6K iso2 (human) ESVKEKFSFEPKIRs S404
p70S6K (mouse) ESVKEKFsFEPKIRs S427-p
p70S6K (rat) ESVKEKFSFEPKIRs S427
p70S6K iso2 (rat) ESVKEKFSFEPKIRS S404
p70S6K (fruit fly) ILEDMHRANRMPARS A411
S434-p
sFEPKIRsPRRFIGs
Upstream
Downstream
28 1
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • DEDD (mouse)
  • ULK1 (mouse)
Treatment
  • IGF-1
  • rapamycin
p70S6K (human) sFEPKIRsPRRFIGs S434-p
p70S6K iso2 (human) SFEPKIRsPRRFIGs S411-p
p70S6K (mouse) sFEPKIRsPRRFIGs S434-p
p70S6K (rat) SFEPKIRsPRRFIGs S434-p
p70S6K iso2 (rat) SFEPKIRSPRRFIGS S411
p70S6K (fruit fly) ANRMPARSPRRTPRQ S418
S441-p
sPRRFIGsPRtPVsP
Upstream
11 117
Regulatory protein:
  • FLT3 (mouse)
Treatment
  • insulin
  • LPS
  • LY294002
  • MK-2206
  • rapamycin
  • troglitazone
view more >
p70S6K (human) sPRRFIGsPRtPVsP S441-p
p70S6K iso2 (human) sPRRFIGsPRtPVsP S418-p
p70S6K (mouse) sPRRFIGsPRtPVsP S441-p
p70S6K (rat) sPRRFIGsPRtPVsP S441-p
p70S6K iso2 (rat) SPRRFIGSPRtPVsP S418
p70S6K (fruit fly) PARSPRRTPRQLPDS T422
T444-p
RFIGsPRtPVsPVKF
Upstream
Downstream
106 141
p70S6K (human)
T444-p
p70S6K (mouse)
T444-p
p70S6K (rat)
T444-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, altered
Regulatory protein:
  • DEDD (mouse)
  • FKBP12 (mouse)
  • IFITM3 (human)
  • IFITM3 (rat)
  • mTOR (mouse)
  • PKCI (mouse)
  • ULK1 (mouse)
view more >
Treatment
  • adriamycin
  • antibody
  • BAPTA-AM
  • benzo(a)pyrene
  • BI-D1870
  • calorie_restriction
  • catalase
  • formate
  • H2O2
  • IGF-1
  • IL-2
  • IL-7
  • insulin
  • LPS
  • LY294002
  • MK-2206
  • NAC
  • NADPH
  • NP68
  • NTCU
  • PD98059
  • pomegranate_wine
  • PP2
  • pressure
  • rapamycin
  • SB203580
  • SOD
  • Torin1
  • troglitazone
  • U0126
  • UV
  • wortmannin
view more >
p70S6K (human) RFIGsPRtPVsPVkF T444-p
p70S6K iso2 (human) RFIGsPRtPVsPVKF T421-p
p70S6K (mouse) RFIGsPRtPVsPVKF T444-p
p70S6K (rat) RFIGsPRtPVsPVKF T444-p
p70S6K iso2 (rat) RFIGSPRtPVsPVKF T421-p
p70S6K (fruit fly) gap -
S447-p
GsPRtPVsPVKFsPG
Upstream
Downstream
102 297
p70S6K (human)
S447-p
p70S6K (mouse)
S447-p
p70S6K (rat)
S447-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, altered
Regulatory protein:
  • DEDD (mouse)
  • FKBP12 (mouse)
  • FLT3 (mouse)
  • IFITM3 (human)
  • IFITM3 (rat)
  • mTOR (mouse)
  • PKCI (mouse)
  • ULK1 (mouse)
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Treatment
  • adriamycin
  • antibody
  • BAPTA-AM
  • benzo(a)pyrene
  • BI-D1870
  • calorie_restriction
  • catalase
  • formate
  • H2O2
  • IGF-1
  • IL-2
  • IL-7
  • insulin
  • LPS
  • LY294002
  • NAC
  • NADPH
  • NP68
  • NTCU
  • PD98059
  • pomegranate_wine
  • PP2
  • pressure
  • rapamycin
  • SB203580
  • SOD
  • Torin1
  • U0126
  • UV
  • wortmannin
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p70S6K (human) GsPRtPVsPVkFsPG S447-p
p70S6K iso2 (human) GsPRtPVsPVKFsPG S424-p
p70S6K (mouse) GsPRtPVsPVKFsPG S447-p
p70S6K (rat) GsPRtPVsPVKFsPG S447-p
p70S6K iso2 (rat) GSPRtPVsPVKFSPG S424-p
p70S6K (fruit fly) gap -
K450
RtPVsPVKFsPGDFW
0 1
p70S6K (human) RtPVsPVkFsPGDFW K450-ub
p70S6K iso2 (human) RtPVsPVKFsPGDFW K427
p70S6K (mouse) RtPVsPVKFsPGDFW K450
p70S6K (rat) RtPVsPVKFsPGDFW K450
p70S6K iso2 (rat) RtPVsPVKFSPGDFW K427
p70S6K (fruit fly) SPRRTPRQLPDSSFR Q425
S452-p
PVsPVKFsPGDFWGR
Upstream
2 98
Treatment
  • insulin
  • LY294002
  • MK-2206
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p70S6K (human) PVsPVkFsPGDFWGR S452-p
p70S6K iso2 (human) PVsPVKFsPGDFWGR S429-p
p70S6K (mouse) PVsPVKFsPGDFWGR S452-p
p70S6K (rat) PVsPVKFsPGDFWGR S452-p
p70S6K iso2 (rat) PVsPVKFSPGDFWGR S429
p70S6K (fruit fly) RRTPRQLPDSSFRLQ P427
S462
DFWGRGASASTANPQ
0 1
p70S6K (human) DFWGRGAsASTANPQ S462-p
p70S6K iso2 (human) DFWGRGASASTANPQ S439
p70S6K (mouse) DFWGRGASASTANPQ S462
p70S6K (rat) DFWGRGASASTANPQ S462
p70S6K iso2 (rat) DFWGRGASASTANPQ S439
p70S6K (fruit fly) SFRLQFPSANVGANA S437
T470
ASTANPQTPVEYPME
1 0
p70S6K (human) ASTANPQtPVEYPME T470-p
p70S6K iso2 (human) ASTANPQTPVEYPME T447
p70S6K (mouse) ASTANPQTPVEYPME T470
p70S6K (rat) ASTANPQTPVEYPME T470
p70S6K iso2 (rat) ASTANPQTPVEYPME T447
p70S6K (fruit fly) gap -
S489-gl
EQMDVTVsGEASAPL
Upstream
Downstream
1 0
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
Regulatory protein:
  • CLEC10A (mouse)
Treatment
  • high-fat diet
p70S6K (human) EQMDVTMSGEASAPL S489
p70S6K iso2 (human) EQMDVTMSGEASAPL S466
p70S6K (mouse) EQMDVTVsGEASAPL S489-gl
p70S6K (rat) EQMDVTTSGEASAPL S489
p70S6K iso2 (rat) EQMDVTTSGEASAPL S466
p70S6K (fruit fly) MHGHSQRSGMFARAT S455
K507-ac
QPNSGPYkkQAFPMI
Downstream
3 0
Effects on Biological Processes:
  • cell growth, induced
p70S6K (human) QPNSGPYKKQAFPMI K507
p70S6K iso2 (human) QPNSGPYkkQAFPMI K484-ac
p70S6K (mouse) QPNSGPYkkQAFPMI K507-ac
p70S6K (rat) QPNSGPYKKQAFPMI K507
p70S6K iso2 (rat) QPNSGPYKKQAFPMI K484
p70S6K (fruit fly) ARATPPHHMQTFAPR H466
K508-ac
PNSGPYkkQAFPMIS
Downstream
3 0
Effects on Biological Processes:
  • cell growth, induced
p70S6K (human) PNSGPYKKQAFPMIS K508
p70S6K iso2 (human) PNSGPYkkQAFPMIS K485-ac
p70S6K (mouse) PNSGPYkkQAFPMIS K508-ac
p70S6K (rat) PNSGPYKKQAFPMIS K508
p70S6K iso2 (rat) PNSGPYKKQAFPMIS K485
p70S6K (fruit fly) RATPPHHMQTFAPRP M467
K516-ac
QAFPMISkRPEHLRM
Downstream
4 1
Effects on Biological Processes:
  • cell growth, induced
p70S6K (human) QAFPMISkRPEHLrM K516-ac
p70S6K iso2 (human) QAFPMISkRPEHLRM K493-ac
p70S6K (mouse) QAFPMISkRPEHLRM K516-ac
p70S6K (rat) QAFPMISKRPEHLRM K516
p70S6K iso2 (rat) QAFPMISKRPEHLRM K493
p70S6K (fruit fly) TFAPRPSPAQDEMMD P476
R522
SkRPEHLRMNL____
0 1
p70S6K (human) SkRPEHLrMNL____ R522-m1
p70S6K iso2 (human) SkRPEHLRMNL____ R499
p70S6K (mouse) SkRPEHLRMNL____ R522
p70S6K (rat) SKRPEHLRMNL____ R522
p70S6K iso2 (rat) SKRPEHLRMNL____ R499
p70S6K (fruit fly) SPAQDEMMDVQGLPM M482