Other Species / Isoforms
  PDHK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S67-p
KQFLDFGsVNACEKT
0 1
PDHK1 (human) KQFLDFGsVNACEKT S67-p
PDHK1 (mouse) KQFLDFGSVNACEKT S67
PDHK1 (rat) KQFLDFGSVNACEKT S67
K92
VRLANIMKEISLLPD
0 1
PDHK1 (human) VRLANIMKEISLLPD K92
PDHK1 (mouse) VRLANIMKEISLLPD K92
PDHK1 (rat) VRLANIMkEISLLPD K92-ac
K133-ub
DKSAEDAkAIyDFTD
0 1
PDHK1 (human) DKSAEDAkAIyDFTD K133-ub
PDHK1 (mouse) DKSAEDAKTIyEFTD K133
PDHK1 (rat) DKSAEDAKTIYEFTD K133
Y136-p
AEDAkAIyDFTDTVI
Upstream
1 3
Kinase, in vitro:
  • FGFR1 (human)
Putative in vivo kinases:
  • FGFR1 (human)
PDHK1 (human) AEDAkAIyDFTDTVI Y136-p
PDHK1 (mouse) AEDAKTIyEFTDTVI Y136-p
PDHK1 (rat) AEDAKTIYEFTDTVI Y136
K214-ac
KGSPSHRkHIGSINP
0 1
PDHK1 (human) KGSPSHRkHIGSINP K214-ac
PDHK1 (mouse) KGSPSHRKHIGSINP K212
PDHK1 (rat) KGSPSHRKHIGSINP K212
K230-ub
CNVLEVIkDGYENAR
0 1
PDHK1 (human) CNVLEVIkDGYENAR K230-ub
PDHK1 (mouse) CDVVEVIKDGYENAR K228
PDHK1 (rat) CDVVEVIKDGYENAR K228
Y243-p
ARRLCDLyyINSPEL
Upstream
Downstream
2 3
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • Abl (human)
  • FGFR1 (human)
  • FLT3 (human)
  • JAK2 (human)
Putative in vivo kinases:
  • FGFR1 (human)
PDHK1 (human) ARRLCDLyyINSPEL Y243-p
PDHK1 (mouse) ARRLCDLyyVNSPEL Y241-p
PDHK1 (rat) ARRLCDLYYVNSPEL Y241
Y244-p
RRLCDLyyINSPELE
Upstream
1 1
Kinase, in vitro:
  • FGFR1 (human)
Putative in vivo kinases:
  • FGFR1 (human)
PDHK1 (human) RRLCDLyyINSPELE Y244-p
PDHK1 (mouse) RRLCDLyyVNSPELE Y242-p
PDHK1 (rat) RRLCDLYYVNSPELE Y242
Y336-p
DRLFNYMyStAPRPR
0 1
PDHK1 (human) DRLFNYMyStAPRPR Y336-p
PDHK1 (mouse) DRLFNYMYSTAPRPR Y334
PDHK1 (rat) DRLFNYMYSTAPRPR Y334
T338-p
LFNYMyStAPRPRVE
Upstream
Downstream
4 1
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
Putative in vivo kinases:
  • PGK1 (human)
Treatment
  • CoCL2
  • EGF
  • GQQ-792
  • hypoxia
  • NG52
  • siRNA
PDHK1 (human) LFNYMyStAPRPRVE T338-p
PDHK1 (mouse) LFNYMYSTAPRPRVE T336
PDHK1 (rat) LFNYMYSTAPRPRVE T336
T346-p
APRPRVEtsRAVPLA
Upstream
Downstream
1 3
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell growth, induced
Kinase, in vitro:
  • Akt1 (human)
  • Akt2 (human)
Putative in vivo kinases:
  • Akt2 (human)
Treatment
  • hypoxia
  • MK-2206
PDHK1 (human) APRPRVEtsRAVPLA T346-p
PDHK1 (mouse) APRPRVEtsRAVPLA T344-p
PDHK1 (rat) APRPRVETSRAVPLA T344
S347-p
PRPRVEtsRAVPLAG
0 3
PDHK1 (human) PRPRVEtsRAVPLAG S347-p
PDHK1 (mouse) PRPRVEtsRAVPLAG S345-p
PDHK1 (rat) PRPRVETSRAVPLAG S345
Y357-p
VPLAGFGyGLPISRL
0 1
PDHK1 (human) VPLAGFGyGLPISRL Y357-p
PDHK1 (mouse) VPLAGFGYGLPISRL Y355
PDHK1 (rat) VPLAGFGYGLPISRL Y355
Y403-p
SIERLPVyNkAAWKH
0 1
PDHK1 (human) SIERLPVyNkAAWKH Y403-p
PDHK1 (mouse) SVERLPVYNKAAWKH Y401
PDHK1 (rat) SIERLPVYNKAAWKH Y401
K405-ub
ERLPVyNkAAWKHYN
0 1
PDHK1 (human) ERLPVyNkAAWKHYN K405-ub
PDHK1 (mouse) ERLPVYNKAAWKHYK K403
PDHK1 (rat) ERLPVYNKAAWKHYR K403