Other Species / Isoforms
  SH2-B-beta (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y48-p
FARRFRLyLAsHPQy
0 2
SH2-B-beta (human) FARRFRLyLAsHPQy Y48-p
SH2-B-beta iso2 (human) FARRFRLYLASHPQY Y48
SH2-B-beta (mouse) LARRFRLYLASHPQY Y48
SH2-B-beta (rat) LARRFRLyLAsHPQY Y48-p
S51-p
RFRLyLAsHPQyAGP
0 4
SH2-B-beta (human) RFRLyLAsHPQyAGP S51-p
SH2-B-beta iso2 (human) RFRLYLASHPQYAGP S51
SH2-B-beta (mouse) RFRLYLASHPQYAEP S51
SH2-B-beta (rat) RFRLyLAsHPQYAEP S51-p
Y55-p
yLAsHPQyAGPGAEA
0 15
SH2-B-beta (human) yLAsHPQyAGPGAEA Y55-p
SH2-B-beta iso2 (human) YLASHPQYAGPGAEA Y55
SH2-B-beta (mouse) YLASHPQYAEPGAEA Y55
SH2-B-beta (rat) yLAsHPQYAEPGAEA Y55
S65-p
PGAEAAFsRRFAELF
0 2
SH2-B-beta (human) PGAEAAFsRRFAELF S65-p
SH2-B-beta iso2 (human) PGAEAAFSRRFAELF S65
SH2-B-beta (mouse) PGAEAAFSGRFAELF S65
SH2-B-beta (rat) PGAEAAFsGRFAELF S65-p
S84-p
EAEVARAsGSLsPPI
0 1
SH2-B-beta (human) EAEVARAsGSLsPPI S84-p
SH2-B-beta iso2 (human) EAEVARASGSLSPPI S84
SH2-B-beta (mouse) EAEVARASGsLsPPV S84
SH2-B-beta (rat) EAEVARASGSLSPPV S84
S86
EVARAsGSLsPPILA
0 1
SH2-B-beta (human) EVARAsGSLsPPILA S86
SH2-B-beta iso2 (human) EVARASGSLSPPILA S86
SH2-B-beta (mouse) EVARASGsLsPPVLA S86-p
SH2-B-beta (rat) EVARASGSLSPPVLA S86
S88-p
ARAsGSLsPPILAPL
0 9
SH2-B-beta (human) ARAsGSLsPPILAPL S88-p
SH2-B-beta iso2 (human) ARASGSLSPPILAPL S88
SH2-B-beta (mouse) ARASGsLsPPVLAPL S88-p
SH2-B-beta (rat) ARASGSLSPPVLAPL S88
S96-p
PPILAPLsPGAEIsP
Upstream
1 16
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • ischemia
  • NGF
  • PD98059
  • phorbol_ester
SH2-B-beta (human) PPILAPLsPGAEIsP S96-p
SH2-B-beta iso2 (human) PPILAPLSPGAEISP S96
SH2-B-beta (mouse) PPVLAPLsPGVEIPP S96-p
SH2-B-beta (rat) PPVLAPLSPGVEIPP S96
S102-p
LsPGAEIsPHDLsLE
0 2
SH2-B-beta (human) LsPGAEIsPHDLsLE S102-p
SH2-B-beta iso2 (human) LSPGAEISPHDLSLE S102
SH2-B-beta (mouse) LsPGVEIPPSHDLSL P102
SH2-B-beta (rat) LSPGVEIPPSHDLSL P102
S107-p
EIsPHDLsLEsCRVG
0 1
SH2-B-beta (human) EIsPHDLsLEsCRVG S107-p
SH2-B-beta iso2 (human) EISPHDLSLESCRVG S107
SH2-B-beta (mouse) IPPSHDLSLESCRVG S108
SH2-B-beta (rat) IPPSHDLSLESCRVG S108
S110-p
PHDLsLEsCRVGGPL
0 1
SH2-B-beta (human) PHDLsLEsCRVGGPL S110-p
SH2-B-beta iso2 (human) PHDLSLESCRVGGPL S110
SH2-B-beta (mouse) SHDLSLESCRVGGPL S111
SH2-B-beta (rat) SHDLSLESCRVGGPL S111
S123-p
PLAVLGPsRssEDLA
0 1
SH2-B-beta (human) PLAVLGPsRssEDLA S123-p
SH2-B-beta iso2 (human) PLAVLGPSRSSEDLA S123
SH2-B-beta (mouse) PLAVLGPSRssEDLA S124
SH2-B-beta (rat) PLAVLGPSRsSEDLA S124
S125-p
AVLGPsRssEDLAGP
0 8
SH2-B-beta (human) AVLGPsRssEDLAGP S125-p
SH2-B-beta iso2 (human) AVLGPSRSSEDLAGP S125
SH2-B-beta (mouse) AVLGPSRssEDLAGP S126-p
SH2-B-beta (rat) AVLGPSRsSEDLAGP S126-p
S126-p
VLGPsRssEDLAGPL
0 4
SH2-B-beta (human) VLGPsRssEDLAGPL S126-p
SH2-B-beta iso2 (human) VLGPSRSSEDLAGPL S126
SH2-B-beta (mouse) VLGPSRssEDLAGPL S127-p
SH2-B-beta (rat) VLGPSRsSEDLAGPL S127
S154-p
PKLKKRFsLRsVGRs
0 1
SH2-B-beta (human) PKLKKRFsLRsVGRs S154-p
SH2-B-beta iso2 (human) PKLKKRFSLRSVGRS S154
SH2-B-beta (mouse) PKLKKRFSLRSVGRS S154
SH2-B-beta (rat) PKLKKRFSLRSVGRs S154
S157-p
KKRFsLRsVGRsVRG
0 3
SH2-B-beta (human) KKRFsLRsVGRsVRG S157-p
SH2-B-beta iso2 (human) KKRFSLRSVGRSVRG S157
SH2-B-beta (mouse) KKRFSLRSVGRSVRG S157
SH2-B-beta (rat) KKRFSLRSVGRsVRG S157
S161-p
sLRsVGRsVRGsVRG
Upstream
Downstream
2 2
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell adhesion, altered
  • cell motility, induced
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • bisindolylmaleimide
  • phorbol_ester
SH2-B-beta (human) sLRsVGRsVRGsVRG S161-p
SH2-B-beta iso2 (human) SLRSVGRSVRGSVRG S161
SH2-B-beta (mouse) SLRSVGRSVRGSVRG S161
SH2-B-beta (rat) SLRSVGRsVRGsVRG S161-p
S165-p
VGRsVRGsVRGILQW
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell adhesion, altered
  • cell motility, induced
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • bisindolylmaleimide
  • phorbol_ester
SH2-B-beta (human) VGRsVRGsVRGILQW S165-p
SH2-B-beta iso2 (human) VGRSVRGSVRGILQW S165
SH2-B-beta (mouse) VGRSVRGSVRGILQW S165
SH2-B-beta (rat) VGRsVRGsVRGILQW S165-p
R211-m1
GGAGTVGrGLVSDGT
0 1
SH2-B-beta (human) GGAGTVGrGLVSDGT R211-m1
SH2-B-beta iso2 (human) GGAGTVGRGLVSDGT R211
SH2-B-beta (mouse) GGAGTVGRALANDGT R211
SH2-B-beta (rat) GGAGTVGRALANDGT R211
S219-p
GLVSDGTsPGERWTH
0 2
SH2-B-beta (human) GLVSDGTsPGERWTH S219-p
SH2-B-beta iso2 (human) GLVSDGTSPGERWTH S219
SH2-B-beta (mouse) ALANDGTsPGERWTH S219-p
SH2-B-beta (rat) ALANDGTSPGERWTH S219
R235-m1
FERLRLSrGGGALKD
0 3
SH2-B-beta (human) FERLRLSrGGGALKD R235-m1
SH2-B-beta iso2 (human) FERLRLSRGGGALKD R235
SH2-B-beta (mouse) FERLRLSrGGGTLKD R235-m1
SH2-B-beta (rat) FERLRLSRGGGTLRD R235
R270-m1
PDPAGVGrGGGVAGP
0 30
SH2-B-beta (human) PDPAGVGrGGGVAGP R270-m1
SH2-B-beta iso2 (human) PDPAGVGRGGGVAGP R270
SH2-B-beta (mouse) PDPAGVGrGGGAAGL R270-m1
SH2-B-beta (rat) PDPAGVGRGGGAAGL R270
K289-ub
GGQPQWQkCRLLLRS
0 1
SH2-B-beta (human) GGQPQWQkCRLLLRS K289-ub
SH2-B-beta iso2 (human) GGQPQWQKCRLLLRS K289
SH2-B-beta (mouse) GGQPQWQKCRLLLRS K289
SH2-B-beta (rat) GGQPQWQKCRLLLRS K289
S320-p
KASRPRLsIPCSSIT
0 4
SH2-B-beta (human) KASRPRLsIPCSSIT S320-p
SH2-B-beta iso2 (human) KASRPRLSIPCSSIT S320
SH2-B-beta (mouse) KASRPRLsIPCSTIT S320-p
SH2-B-beta (rat) KASRPRLSIPCSTIT S320
S352-p
VVKVEGPsEYIMETV
0 1
SH2-B-beta (human) VVKVEGPsEYIMETV S352-p
SH2-B-beta iso2 (human) VVKVEGPSEYIMETV S352
SH2-B-beta (mouse) VVKVEGPSEYILETS S352
SH2-B-beta (rat) VVKVEGPSEYILETT S352
S376-p
SDIQECLsPGPCPAT
0 1
SH2-B-beta (human) SDIQECLsPGPCPAT S376-p
SH2-B-beta iso2 (human) SDIQECLSPGPCPAT S376
SH2-B-beta (mouse) SDIQECLSPGPCPAI S376
SH2-B-beta (rat) SDIQECLSPGPCPAI S376
S384-p
PGPCPATsPRPMTLP
0 1
SH2-B-beta (human) PGPCPATsPRPMTLP S384-p
SH2-B-beta iso2 (human) PGPCPATSPRPMTLP S384
SH2-B-beta (mouse) PGPCPAISPRPMTLP S384
SH2-B-beta (rat) PGPCPAISPRPMTLP S384
S417-p
SCLNHSEsLPSQDLL
0 2
SH2-B-beta (human) SCLNHSEsLPSQDLL S417-p
SH2-B-beta iso2 (human) SCLNHSESLPSQDLL S417
SH2-B-beta (mouse) PCLNHSEsLPsQDLL S417-p
SH2-B-beta (rat) PCLNHSESLPSQDLL S417
S420
NHSEsLPSQDLLLGP
0 1
SH2-B-beta (human) NHSEsLPSQDLLLGP S420
SH2-B-beta iso2 (human) NHSESLPSQDLLLGP S420
SH2-B-beta (mouse) NHSEsLPsQDLLLGP S420-p
SH2-B-beta (rat) NHSESLPSQDLLLGP S420
Y439-p
DRLSQGAyGGLSDRP
2 2
SH2-B-beta (human) DRLSQGAyGGLSDRP Y439-p
SH2-B-beta iso2 (human) DRLSQGAYGGLSDRP Y439
SH2-B-beta (mouse) DRLSQGAYGGLSDRP Y439
SH2-B-beta (rat) DRLSQGAyGGLSDRP Y439-p
Y494
VHPLSAPYPPLDTPE
2 0
SH2-B-beta (human) VHPLSAPYPPLDTPE Y494
SH2-B-beta iso2 (human) VHPLSAPYPPLDTPE Y494
SH2-B-beta (mouse) VHPLSTPYPPLDTPE Y494
SH2-B-beta (rat) VHPLSTPyPPLDTPE Y494-p
S580-p
KAKHLRLsLNEEGQC
0 2
SH2-B-beta (human) KAKHLRLsLNEEGQC S580-p
SH2-B-beta iso2 (human) KAKHLRLSLNEEGQC S580
SH2-B-beta (mouse) KAKHLRLSLNEEGQC S580
SH2-B-beta (rat) KAKHLRLSLNEEGQC S580
Y624-p
SDVVLVSyVPSSQRQ
0 1
SH2-B-beta (human) SDVVLVSyVPSSQRQ Y624-p
SH2-B-beta iso2 (human) SDVVLVSYVPSSQRQ Y624
SH2-B-beta (mouse) SDVVLVSYVPSQRQQ Y624
SH2-B-beta (rat) SDVVLVSYVPSQRQQ Y624
Y753-p
PRAINNQySFV____
Upstream
Downstream
1 0
Effects on Biological Processes:
  • cell growth, inhibited
  • signaling pathway regulation
Putative in vivo kinases:
  • TrkA (human)
Treatment
  • NGF
SH2-B-beta (human) PRAINNQySFV____ Y753-p
SH2-B-beta iso2 (human) gap -
SH2-B-beta (mouse) PRAINNQYSFV____ Y753
SH2-B-beta (rat) gap -