Other Species / Isoforms
  PINK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K135
IQAIFTQKSkPGPDP
0 1
PINK1 (human) IQAIFTQKSkPGPDP K135
PINK1 (mouse) IQAIFTQkTKRVSDP K135-ub
PINK1 (rat) IQAIFTQKNKQVSDP K135
K137-ub
AIFTQKSkPGPDPLD
1 1
PINK1 (human) AIFTQKSkPGPDPLD K137-ub
PINK1 (mouse) AIFTQkTKRVSDPLD K137
PINK1 (rat) AIFTQKNKQVSDPLD K137
K164-ub
LIGQSIGkGCSAAVY
0 1
PINK1 (human) LIGQSIGkGCSAAVY K164-ub
PINK1 (mouse) LIGQAIGKGCNAAVY K164
PINK1 (rat) LIGQAIGKGCNAAVY K164
K186-ub
PQNLEVTkSTGLLPG
0 2
PINK1 (human) PQNLEVTkSTGLLPG K186-ub
PINK1 (mouse) PQHLEKAKHLGLIGK K186
PINK1 (rat) PQHLEKAKHLGLLGK K186
S228-p
MWNISAGsSSEAILN
Upstream
Downstream
6 2
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • ubiquitination
Kinase, in vitro:
  • PINK1 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
  • PINK1 (human)
Treatment
  • CCCP
  • lactacystin
PINK1 (human) MWNISAGsSSEAILN S228-p
PINK1 (mouse) MWNISAGSSSEAILS S227
PINK1 (rat) MWNISAGSSSEAILS S227
T257-p
AGEYGAVtYRKSkRG
Upstream
Downstream
1 3
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • PINK1 (human)
Putative in vivo kinases:
  • PINK1 (human)
Treatment
  • CCCP
PINK1 (human) AGEYGAVtYRKSkRG T257-p
PINK1 (mouse) AGEYGAVTYRRsRDG T256
PINK1 (rat) DGEYGAVTYRRSRDG T256
S261
GAVtYRKSkRGPKQL
0 1
PINK1 (human) GAVtYRKSkRGPKQL S261
PINK1 (mouse) GAVTYRRsRDGPKQL S260-p
PINK1 (rat) GAVTYRRSRDGPKQL S260
K262-ac
AVtYRKSkRGPKQLA
0 1
PINK1 (human) AVtYRKSkRGPKQLA K262-ac
PINK1 (mouse) AVTYRRsRDGPKQLA R261
PINK1 (rat) AVTYRRSRDGPKQLA R261
S284-p
VLRAFTSsVPLLPGA
Upstream
1 1
Putative in vivo kinases:
  • AMPKA2 (human)
PINK1 (human) VLRAFTSsVPLLPGA S284-p
PINK1 (mouse) VFRAFTSSVPLLPGA S283
PINK1 (rat) VFRAFTSSVPLLPGA S283
T313-p
EGLGHGRtLFLVMkN
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • MARK2 (human)
Putative in vivo kinases:
  • MARK2 (human)
PINK1 (human) EGLGHGRtLFLVMkN T313-p
PINK1 (mouse) EGLGHGRTLFLVMKN T312
PINK1 (rat) EGLGHGRTLFLVMKN T312
K319-ub
RtLFLVMkNYPCTLR
0 1
PINK1 (human) RtLFLVMkNYPCTLR K319-ub
PINK1 (mouse) RTLFLVMKNYPCTLR K318
PINK1 (rat) RTLFLVMKNYPCTLR K318
S402-p
GLQLPFSsWYVDRGG
Upstream
Downstream
5 1
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein conformation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
Kinase, in vitro:
  • PINK1 (human)
Putative in vivo kinases:
  • PINK1 (human)
Treatment
  • CCCP
  • lactacystin
PINK1 (human) GLQLPFSsWYVDRGG S402-p
PINK1 (mouse) GLRLPFNSSSVERGG S401
PINK1 (rat) GLQLPFNSSSVERGG S401
K433-ub
RAVIDYSkADAWAVG
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Regulatory protein:
  • SARM1 (human)
PINK1 (human) RAVIDYSkADAWAVG K433-ub
PINK1 (mouse) SAVIDYSKADTWAVG K432
PINK1 (rat) HAVIDYSKADTWAVG K432
S495-p
ALLQREAsKRPSARV
Upstream
Downstream
1 1
Effects on Biological Processes:
  • autophagy, induced
Putative in vivo kinases:
  • AMPKA2 (human)
PINK1 (human) ALLQREAsKRPSARV S495-p
PINK1 (mouse) SLLQREASKRPSARL S494
PINK1 (rat) SLLQREANKRPSARI N494
K547-ub
LANRLTEkCCVETKM
0 1
PINK1 (human) LANRLTEkCCVETKM K547-ub
PINK1 (mouse) LADRLREKSCVETKL K546
PINK1 (rat) LADRLREKSCVETKL K546