Other Species / Isoforms
  AurA (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MDRsKENCIsG
0 2
AurA (human) ____MDRsKENCIsG S4-p
AurA (mouse) ____MDRCKENCVSR C4
AurA (rat) ____MDRCKENCVSR C4
AurA (pig) ____MDKCKENCISG C4
AurA (frog) gap -
S10-p
RsKENCIsGPVkAtA
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) RsKENCIsGPVkAtA S10-p
AurA (mouse) RCKENCVSRPVKTTV S10
AurA (rat) RCKENCVSRPVKSTV S10
AurA (pig) KCKENCISGLKTTVP S10
AurA (frog) AVKENHKPsNVKIFH P11
G11
sKENCIsGPVkAtAP
0 1
AurA (human) sKENCIsGPVkAtAP G11
AurA (mouse) CKENCVSRPVKTTVP R11
AurA (rat) CKENCVSRPVKSTVP R11
AurA (pig) CKENCISGLKTTVPP G11
AurA (frog) VKENHKPsNVKIFHP S12-p
K14-me
NCIsGPVkAtAPVGG
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • transcription, induced
Treatment
  • siRNA
AurA (human) NCIsGPVkAtAPVGG K14-me
AurA (mouse) NCVSRPVKTTVPFGP K14
AurA (rat) NCVSRPVKSTVPFGP K14
AurA (pig) ENCISGLKTTVPPGD K13
AurA (frog) NHKPsNVKIFHPMtE K15
T16-p
IsGPVkAtAPVGGPk
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) IsGPVkAtAPVGGPk T16-p
AurA (mouse) VSRPVKTTVPFGPKR T16
AurA (rat) VSRPVKSTVPFGPKR T16
AurA (pig) CISGLKTTVPPGDGP T15
AurA (frog) KPsNVKIFHPMtEGA F17
G20
VkAtAPVGGPkRVLV
0 1
AurA (human) VkAtAPVGGPkRVLV G20
AurA (mouse) VKTTVPFGPKRVLVT G20
AurA (rat) VKSTVPFGPKRVLVT G20
AurA (pig) LKTTVPPGDGPKRVP G19
AurA (frog) VKIFHPMtEGAKRIP T21-p
K23-ub
tAPVGGPkRVLVTQQ
0 1
AurA (human) tAPVGGPkRVLVTQQ K23-ub
AurA (mouse) TTVPFGPKRVLVTEQ K22
AurA (rat) STVPFGPKRVLVTEQ K22
AurA (pig) VPPGDGPKRVPVTQH K23
AurA (frog) HPMtEGAKRIPVNQP K25
S41-p
QNPLPVNsGQAQRVL
Upstream
1 3
Kinase, in vitro:
  • AurA (human)
Treatment
  • MG132_withdrawal
  • nocodazole
  • thymidine
view more >
AurA (human) QNPLPVNsGQAQRVL S41-p
AurA (mouse) QNLGSASSGQAQRVL S40
AurA (rat) QHPGSASSGQAQRVL S40
AurA (pig) QHLPSANSGQAQRVL S41
AurA (frog) QFRPPGTAVSAQRIL A43
S51-p
AQRVLCPsNssQRIP
Upstream
Downstream
2 3
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, induced
Putative upstream phosphatases:
  • PPP2CA (human)
Treatment
  • BI2536
  • nocodazole
  • okadaic_acid
  • thymidine
view more >
AurA (human) AQRVLCPsNssQRIP S51-p
AurA (mouse) AQRVLCPSNSQRVPS S50
AurA (rat) AQRVLCPSNSQRVPP S50
AurA (pig) AQRVLCPSNSSQRLP S51
AurA (frog) AQRILGPsNVPQRVL S53-p
S53-p
RVLCPsNssQRIPLQ
Upstream
0 2
Treatment
  • MG132
  • MG132_withdrawal
AurA (human) RVLCPsNssQRIPLQ S53-p
AurA (mouse) RVLCPSNSQRVPSQA S52
AurA (rat) RVLCPSNSQRVPPQA S52
AurA (pig) RVLCPSNSSQRLPSH S53
AurA (frog) RILGPsNVPQRVLAQ V55
S54-p
VLCPsNssQRIPLQA
0 1
AurA (human) VLCPsNssQRIPLQA S54-p
AurA (mouse) gap -
AurA (rat) gap -
AurA (pig) VLCPSNSSQRLPSHT S54
AurA (frog) ILGPsNVPQRVLAQA P56
K63
RIPLQAQKLVssHkP
0 1
AurA (human) RIPLQAQKLVssHkP K63
AurA (mouse) RVPSQAQKLGAGQKP K61
AurA (rat) RVPPQAQkPVAGQKP K61-ac
AurA (pig) RLPSHTQKLVSSHKP K63
AurA (frog) RVLAQAQKPILSSQK K65
K63-ub
RIPLQAQkLVssHkP
0 1
AurA (human) RIPLQAQkLVssHkP K63-ub
AurA (mouse) RVPSQAQKLGAGQKP K61
AurA (rat) RVPPQAQKPVAGQKP K61
AurA (pig) RLPSHTQKLVSSHKP K63
AurA (frog) RVLAQAQKPILSSQK K65
S66-p
LQAQkLVssHkPVQN
Upstream
0 1
Treatment
  • MG132_withdrawal
AurA (human) LQAQkLVssHkPVQN S66-p
AurA (mouse) SQAQKLGAGQKPAPK A64
AurA (rat) PQAQkPVAGQKPVLK A64
AurA (pig) SHTQKLVSSHKPVQN S66
AurA (frog) QAQKPILSSQKPTTQ S69
S67-p
QAQkLVssHkPVQNQ
Upstream
1 2
Kinase, in vitro:
  • AurA (human)
AurA (human) QAQkLVssHkPVQNQ S67-p
AurA (mouse) QAQKLGAGQKPAPKQ G65
AurA (rat) QAQkPVAGQKPVLKQ G65
AurA (pig) HTQKLVSSHKPVQNL S67
AurA (frog) AQKPILSSQKPTTQI S70
K69-ub
QkLVssHkPVQNQkQ
0 1
AurA (human) QkLVssHkPVQNQkQ K69-ub
AurA (mouse) QKLGAGQKPAPKQLP K67
AurA (rat) QkPVAGQKPVLKQLP K67
AurA (pig) QKLVSSHKPVQNLKQ K69
AurA (frog) KPILSSQKPTTQIPL K72
K75-ac
HkPVQNQkQKQLQAT
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • cell motility, induced
AurA (human) HkPVQNQkQKQLQAT K75-ac
AurA (mouse) gap -
AurA (rat) gap -
AurA (pig) HKPVQNLKQKQSQAT K75
AurA (frog) gap -
S83-p
QKQLQATsVPHPVsR
Upstream
1 2
Kinase, in vitro:
  • AurA (human)
AurA (human) QKQLQATsVPHPVsR S83-p
AurA (mouse) PKQLPAASVPRPVSR S77
AurA (rat) LKQLPAASGPRPASR S77
AurA (pig) QKQSQATSGPRPVSR S83
AurA (frog) ATQGHQSSKPQGPNE S89
S89-p
TsVPHPVsRPLNNTQ
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
  • cytoskeletal reorganization
AurA (human) TsVPHPVsRPLNNTQ S89-p
AurA (mouse) ASVPRPVSRLNNPQK S83
AurA (rat) ASGPRPASRLSNPQK S83
AurA (pig) TSGPRPVSRPLSNTQ S89
AurA (frog) SSKPQGPNENRNPQQ N95
K97
RPLNNTQKskQPLPs
0 1
AurA (human) RPLNNTQKskQPLPs K97
AurA (mouse) SRLNNPQKNEQPAAS K90
AurA (rat) SRLSNPQKSEQPQPA K90
AurA (pig) RPLSNTQQSEQPQPA Q97
AurA (frog) ENRNPQQtSHSSTPN T103-p
S98-p
PLNNTQKskQPLPsA
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) PLNNTQKskQPLPsA S98-p
AurA (mouse) RLNNPQKNEQPAASG N91
AurA (rat) RLSNPQKSEQPQPAA S91
AurA (pig) PLSNTQQSEQPQPAA S98
AurA (frog) NRNPQQtSHSSTPNV S104
K99-ub
LNNTQKskQPLPsAP
0 1
AurA (human) LNNTQKskQPLPsAP K99-ub
AurA (mouse) LNNPQKNEQPAASGN E92
AurA (rat) LSNPQKSEQPQPAAS E92
AurA (pig) LSNTQQSEQPQPAAP E99
AurA (frog) gap -
S104-p
KskQPLPsAPENNPE
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) KskQPLPsAPENNPE S104-p
AurA (mouse) PQKNEQPAASGNDSE A95
AurA (rat) KSEQPQPAASGNNSE A97
AurA (pig) QSEQPQPAAPGNNPE A104
AurA (frog) gap -
L114
ENNPEEELAskQKNE
0 1
AurA (human) ENNPEEELAskQKNE L114
AurA (mouse) GNDSEKEQASLQKTE Q105
AurA (rat) GNNSEKEQTSIQKTE Q107
AurA (pig) GNNPEKEAASKQKNE A114
AurA (frog) PNVEKKGsTDQGKtS S116-p
S116-p
NPEEELAskQKNEES
0 1
AurA (human) NPEEELAskQKNEES S116-p
AurA (mouse) DSEKEQASLQKTEDT S107
AurA (rat) NSEKEQTSIQKTEDS S109
AurA (pig) NPEKEAASKQKNEES S116
AurA (frog) VEKKGsTDQGKtSAV D118
K117-me
PEEELAskQKNEESK
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • transcription, induced
Treatment
  • siRNA
AurA (human) PEEELAskQKNEESK K117-me
AurA (mouse) SEKEQASLQKTEDTK L108
AurA (rat) SEKEQTSIQKTEDSK I110
AurA (pig) PEKEAASKQKNEESK K117
AurA (frog) EKKGsTDQGKtSAVP Q119
K117-ub
PEEELAskQKNEESK
0 1
AurA (human) PEEELAskQKNEESK K117-ub
AurA (mouse) SEKEQASLQKTEDTK L108
AurA (rat) SEKEQTSIQKTEDSK I110
AurA (pig) PEKEAASKQKNEESK K117
AurA (frog) EKKGsTDQGKtSAVP Q119
N120
ELAskQKNEESKkRQ
0 1
AurA (human) ELAskQKNEESKkRQ N120
AurA (mouse) EQASLQKTEDTKKRQ T111
AurA (rat) EQTSIQKTEDSKKRQ T113
AurA (pig) EAASKQKNEESKKRQ N120
AurA (frog) GsTDQGKtSAVPKEE T122-p
K125-ac
QKNEESKkRQWALED
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • cell motility, induced
AurA (human) QKNEESKkRQWALED K125-ac
AurA (mouse) QKTEDTKKRQWTLED K116
AurA (rat) QKTEDSKKRQWTLED K118
AurA (pig) QKNEESKKRQWALED K125
AurA (frog) VPKEEGKKKQWCLED K132
K141-ub
EIGRPLGkGkFGNVy
0 1
AurA (human) EIGRPLGkGkFGNVy K141-ub
AurA (mouse) DIGRPLGKGKFGNVY K132
AurA (rat) DIGRPLGKGKFGNVY K134
AurA (pig) EIGRPLGKGKFGNVY K141
AurA (frog) EIGRPLGKGKFGNVy K148
K143-ub
GRPLGkGkFGNVyLA
Upstream
Downstream
1 6
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
Treatment
  • MG132
AurA (human) GRPLGkGkFGNVyLA K143-ub
AurA (mouse) GRPLGKGKFGNVYLA K134
AurA (rat) GRPLGKGKFGNVYLA K136
AurA (pig) GRPLGKGKFGNVYLA K143
AurA (frog) GRPLGKGKFGNVyLA K150
Y148-p
kGkFGNVyLAREKQS
Upstream
Downstream
2 12
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • AurA (human)
Putative in vivo kinases:
  • Src (human)
AurA (human) kGkFGNVyLAREKQS Y148-p
AurA (mouse) KGKFGNVYLARERQS Y139
AurA (rat) KGKFGNVYLAREKQS Y141
AurA (pig) KGKFGNVYLAREKQS Y148
AurA (frog) KGKFGNVyLARERES Y155-p
S226-p
YRELQKLskFDEQRT
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) YRELQKLskFDEQRT S226-p
AurA (mouse) YRELQKLSKFDEQRT S217
AurA (rat) YRELQKLSKFDEQRT S219
AurA (pig) YRELQKLSKFDEQRT S226
AurA (frog) FRELQKCTRFDDQRS T233
K227-ub
RELQKLskFDEQRTA
0 1
AurA (human) RELQKLskFDEQRTA K227-ub
AurA (mouse) RELQKLSKFDEQRTA K218
AurA (rat) RELQKLSKFDEQRTA K220
AurA (pig) RELQKLSKFDEQRTA K227
AurA (frog) RELQKCTRFDDQRSA R234
K250-ub
ALSYCHSkRVIHRDI
0 2
AurA (human) ALSYCHSkRVIHRDI K250-ub
AurA (mouse) ALSYCHSKRVIHRDI K241
AurA (rat) ALSYCHSKRVIHRDI K243
AurA (pig) ALSYCHSKRVIHRDI K250
AurA (frog) ALLYCHSKKVIHRDI K257
K258-ub
RVIHRDIkPENLLLG
0 2
AurA (human) RVIHRDIkPENLLLG K258-ub
AurA (mouse) RVIHRDIKPENLLLG K249
AurA (rat) RVIHRDIKPENLLLG K251
AurA (pig) RVIHRDIKPENLLLG K258
AurA (frog) KVIHRDIKPENLLLG K265
S266-p
PENLLLGsAGELKIA
Upstream
1 2
Kinase, in vitro:
  • AurA (human)
AurA (human) PENLLLGsAGELKIA S266-p
AurA (mouse) PENLLLGSNGELKIA S257
AurA (rat) PENLLLGSNGELKIA S259
AurA (pig) PENLLLGSAGELKIA S266
AurA (frog) PENLLLGSNGELKIA S273
S278-p
KIADFGWsVHAPssR
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) KIADFGWsVHAPssR S278-p
AurA (mouse) KIADFGWSVHAPSSR S269
AurA (rat) KIADFGWSVHAPSSR S271
AurA (pig) KIADFGWSVHAPssR S278
AurA (frog) KIADFGWSVHAPSSR S285
S283-p
GWsVHAPssRRttLC
Upstream
Downstream
2 0
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
AurA (human) GWsVHAPssRRttLC S283-p
AurA (mouse) GWSVHAPSSRRTtMC S274
AurA (rat) GWSVHAPSSRRTtLC S276
AurA (pig) GWSVHAPssRRTtLC S283-p
AurA (frog) GWSVHAPSSRRttLC S290
S284-p
WsVHAPssRRttLCG
Upstream
Downstream
3 0
Effects on Modified Protein
  • enzymatic activity, induced
  • protein degradation
  • ubiquitination
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
AurA (human) WsVHAPssRRttLCG S284-p
AurA (mouse) WSVHAPSSRRTtMCG S275
AurA (rat) WSVHAPSSRRTtLCG S277
AurA (pig) WSVHAPssRRTtLCG S284-p
AurA (frog) WSVHAPSSRRttLCG S291
T287-p
HAPssRRttLCGtLD
Upstream
Downstream
5 7
Effects on Modified Protein
  • enzymatic activity, induced
  • enzymatic activity, inhibited
Kinase, in vitro:
  • AurA (human)
Treatment
  • MG132
AurA (human) HAPssRRttLCGtLD T287-p
AurA (mouse) HAPSSRRTtMCGTLD T278
AurA (rat) HAPSSRRTtLCGTLD T280
AurA (pig) HAPssRRTtLCGTLD T287
AurA (frog) HAPSSRRttLCGTLD T294-p
T288-p
APssRRttLCGtLDy
Upstream
Downstream
70 19
AurA (human)
T288-p
AurA (mouse)
T279-p
AurA (rat)
T281-p
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, induced
  • cell cycle regulation
  • cell motility, induced
  • cytoskeletal reorganization
  • transcription, induced
Kinase, in vitro:
  • AurA (human)
  • PAK1 (human)
  • PKACA (human)
view more >
Phosphatases, in vitro:
  • PPP1CA (human)
  • PPP6C (human)
Putative in vivo kinases:
  • AurA (human)
  • AurA (mouse)
  • PAK1 (human)
view more >
Putative upstream phosphatases:
  • PPP6C (human)
Regulatory protein:
  • APOA1BP (human)
  • ARPC1B (human)
  • DNAPK (human)
  • ENSA (human)
  • FIRRM (human)
  • KCTD12 (human)
  • KIBRA (human)
  • LIN28B (human)
  • PPP6C (human)
  • PYGO2 (human)
  • RAN (human)
  • Rb (human)
  • SPACA6P (human)
  • TFEB (human)
  • TPX2 (human)
view more >
Treatment
  • 2-(2-amino-6-(2,4-dimethoxyphenyl)pyrimidin-4-yl)phenol
  • antimycin_A
  • Aurora_A_Inhibitor_I
  • BI2536
  • cAMP_analog
  • colforsin
  • dasatinib
  • DTT
  • H-89
  • H1152
  • hesperadin
  • HXDV
  • ionizing_radiation
  • KU-55933
  • MG132
  • MK5108
  • MKI-2
  • MLN8054
  • MLN8237
  • MLN9708
  • nocodazole
  • NU7441
  • okadaic_acid
  • PP1
  • rotenone
  • siRNA
  • TAME
  • tamoxifen
  • thymidine
  • VX-680
  • ZM447439
view more >
AurA (human) APssRRttLCGtLDy T288-p
AurA (mouse) APSSRRTtMCGTLDY T279-p
AurA (rat) APSSRRTtLCGTLDY T281-p
AurA (pig) APssRRTtLCGTLDY T288-p
AurA (frog) APSSRRttLCGTLDY T295-p
T292-p
RRttLCGtLDyLPPE
Upstream
0 16
Treatment
  • AZD1152
  • BI2536
  • MG132
  • MLN8054
  • ZM447439
view more >
AurA (human) RRttLCGtLDyLPPE T292-p
AurA (mouse) RRTtMCGTLDYLPPE T283
AurA (rat) RRTtLCGTLDYQPPE T285
AurA (pig) RRTtLCGTLDYLPPE T292
AurA (frog) RRttLCGTLDYLPPE T299
Y295-p
tLCGtLDyLPPEMIE
Upstream
0 7
Treatment
  • MG132
AurA (human) tLCGtLDyLPPEMIE Y295-p
AurA (mouse) tMCGTLDYLPPEMIE Y286
AurA (rat) tLCGTLDYQPPEMIE Y288
AurA (pig) tLCGTLDYLPPEMIE Y295
AurA (frog) tLCGTLDYLPPEMIE Y302
R304-me
PPEMIEGrMHDEKVD
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Treatment
  • siRNA
AurA (human) PPEMIEGrMHDEKVD R304-me
AurA (mouse) PPEMIEGRMHDEKVD R295
AurA (rat) PPEMIEGRMHDEKVD R297
AurA (pig) PPEMIEGRMHDEKVD R304
AurA (frog) PPEMIEGRMHDETVD R311
S342-p
QETYKRIsRVEFTFP
Upstream
Downstream
4 2
Effects on Modified Protein
  • enzymatic activity, induced
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
  • cytoskeletal reorganization
Kinase, in vitro:
  • AurA (human)
  • PAK1 (human)
Putative in vivo kinases:
  • AurA (human)
Regulatory protein:
  • EEF1A2 (human)
Treatment
  • MK-2206
AurA (human) QETYKRIsRVEFTFP S342-p
AurA (mouse) QETYRRISRVEFTFP S333
AurA (rat) QETYRRISRVEFTFP S335
AurA (pig) QETYKRISRVEFTFP S342
AurA (frog) QETYRRIsKVEFQYP S349-p
S369-p
RLLKHNPsQRPMLRE
0 1
AurA (human) RLLKHNPsQRPMLRE S369-p
AurA (mouse) RLLKHNASQRLTLAE S360
AurA (rat) RLLKHNSSQRLTLAE S362
AurA (pig) RLLKHNPSHRPTLKE S369
AurA (frog) KLLKHNPNHRLPLKG N376
S391-p
TANSSKPsNCQNKES
Upstream
1 1
Kinase, in vitro:
  • AurA (human)
AurA (human) TANSSKPsNCQNKES S391-p
AurA (mouse) ANSSKPPTGHTSKEP T383
AurA (rat) ANSSKPPTGHNSKEA T385
AurA (pig) ITANSKPASSHKKES A390
AurA (frog) gap -