Other Species / Isoforms
  MELK (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K2-ub
______MkDyDELLk
0 2
MELK (human) ______MkDyDELLk K2-ub
MELK (mouse) ______MKDyDELLK K2
MELK (rat) under review -
Y4-p
____MkDyDELLkYY
0 5
MELK (human) ____MkDyDELLkYY Y4-p
MELK (mouse) ____MKDyDELLKYY Y4-p
MELK (rat) under review -
K9-ub
kDyDELLkYYELHET
0 1
MELK (human) kDyDELLkYYELHET K9-ub
MELK (mouse) KDyDELLKYYELYET K9
MELK (rat) under review -
K24-ub
IGTGGFAkVKLACHI
0 1
MELK (human) IGTGGFAkVKLACHI K24-ub
MELK (mouse) IGTGGFAKVKLACHV K24
MELK (rat) under review -
K44-ub
VAIKIMDkNTLGsDL
0 4
MELK (human) VAIKIMDkNTLGsDL K44-ub
MELK (mouse) VAIKIMDKNALGsDL K44
MELK (rat) under review -
S49-p
MDkNTLGsDLPRIkt
0 2
MELK (human) MDkNTLGsDLPRIkt S49-p
MELK (mouse) MDKNALGsDLPRVKT S49-p
MELK (rat) under review -
K55-ub
GsDLPRIktEIEALk
0 3
MELK (human) GsDLPRIktEIEALk K55-ub
MELK (mouse) GsDLPRVKTEIDALK K55
MELK (rat) under review -
K55-sm
GsDLPRIktEIEALk
0 1
MELK (human) GsDLPRIktEIEALk K55-sm
MELK (mouse) GsDLPRVKTEIDALK K55
MELK (rat) under review -
T56-p
sDLPRIktEIEALkN
Upstream
1 0
Kinase, in vitro:
  • MELK (human)
MELK (human) sDLPRIktEIEALkN T56-p
MELK (mouse) sDLPRVKTEIDALKS T56
MELK (rat) under review -
K62-ub
ktEIEALkNLRHQHI
0 4
MELK (human) ktEIEALkNLRHQHI K62-ub
MELK (mouse) KTEIDALKSLRHQHI K62
MELK (rat) under review -
S118
VVFRQIVSAVAYVHS
0 1
MELK (human) VVFRQIVSAVAYVHS S118
MELK (mouse) VVFRQILsAVAyVHs S118-p
MELK (rat) under review -
Y122
QIVSAVAYVHSQGYA
0 1
MELK (human) QIVSAVAYVHSQGYA Y122
MELK (mouse) QILsAVAyVHsQGyA Y122-p
MELK (rat) under review -
S125
SAVAYVHSQGYAHRD
0 1
MELK (human) SAVAYVHSQGYAHRD S125
MELK (mouse) sAVAyVHsQGyAHRD S125-p
MELK (rat) under review -
Y128
AYVHSQGYAHRDLkP
0 1
MELK (human) AYVHSQGYAHRDLkP Y128
MELK (mouse) AyVHsQGyAHRDLKP Y128-p
MELK (rat) under review -
K134-ub
GYAHRDLkPENLLFD
0 2
MELK (human) GYAHRDLkPENLLFD K134-ub
MELK (mouse) GyAHRDLKPENLLFD K134
MELK (rat) under review -
K145-ub
LLFDEYHkLkLIDFG
0 1
MELK (human) LLFDEYHkLkLIDFG K145-ub
MELK (mouse) LLFDENHKLKLIDFG K145
MELK (rat) under review -
K147-ub
FDEYHkLkLIDFGLC
0 2
MELK (human) FDEYHkLkLIDFGLC K147-ub
MELK (mouse) FDENHKLKLIDFGLC K147
MELK (rat) under review -
K156-ub
IDFGLCAkPKGNkDy
0 1
MELK (human) IDFGLCAkPKGNkDy K156-ub
MELK (mouse) IDFGLCAKPKGNKDY K156
MELK (rat) under review -
K161-ub
CAkPKGNkDyHLQtC
0 2
MELK (human) CAkPKGNkDyHLQtC K161-ub
MELK (mouse) CAKPKGNKDYHLQTC K161
MELK (rat) under review -
Y163-p
kPKGNkDyHLQtCCG
Upstream
1 0
Kinase, in vitro:
  • MELK (human)
MELK (human) kPKGNkDyHLQtCCG Y163-p
MELK (mouse) KPKGNKDYHLQTCCG Y163
MELK (rat) under review -
T167-p
NkDyHLQtCCGsLAY
Upstream
Downstream
3 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • LKB1 (human)
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
Treatment
  • sanguinarine
MELK (human) NkDyHLQtCCGsLAY T167-p
MELK (mouse) NKDYHLQTCCGSLAY T167
MELK (rat) under review -
S171-p
HLQtCCGsLAYAAPE
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • MELK (human)
Treatment
  • sanguinarine
MELK (human) HLQtCCGsLAYAAPE S171-p
MELK (mouse) HLQTCCGSLAYAAPE S171
MELK (rat) under review -
K225-ub
YKKIMRGkyDVPKWL
0 2
MELK (human) YKKIMRGkyDVPKWL K225-ub
MELK (mouse) YKKIMRGKYEVPKWL K225
MELK (rat) under review -
Y226-p
KKIMRGkyDVPKWLS
0 1
MELK (human) KKIMRGkyDVPKWLS Y226-p
MELK (mouse) KKIMRGKYEVPKWLS Y226
MELK (rat) under review -
S236-p
PKWLSPSsILLLQQM
0 1
MELK (human) PKWLSPSsILLLQQM S236-p
MELK (mouse) PKWLSPSSILLLQQM S236
MELK (rat) under review -
S253-p
VDPKKRIsMkNLLNH
Upstream
1 0
Kinase, in vitro:
  • MELK (human)
MELK (human) VDPKKRIsMkNLLNH S253-p
MELK (mouse) VDPKKRISMRNLLNH S253
MELK (rat) under review -
K255-ub
PKKRIsMkNLLNHPW
0 1
MELK (human) PKKRIsMkNLLNHPW K255-ub
MELK (mouse) PKKRISMRNLLNHPW R255
MELK (rat) under review -
Y267-p
HPWIMQDyNyPVEWQ
0 6
MELK (human) HPWIMQDyNyPVEWQ Y267-p
MELK (mouse) HPWVMQDYSCPVEWQ Y267
MELK (rat) under review -
Y269-p
WIMQDyNyPVEWQSK
0 4
MELK (human) WIMQDyNyPVEWQSK Y269-p
MELK (mouse) WVMQDYSCPVEWQSK C269
MELK (rat) under review -
S335-p
KPVRLRLssFsCGQA
0 16
MELK (human) KPVRLRLssFsCGQA S335-p
MELK (mouse) KPARLQLLSFSCGTA L335
MELK (rat) under review -
S336-p
PVRLRLssFsCGQAs
Upstream
1 17
Kinase, in vitro:
  • MELK (human)
Treatment
  • MG132_withdrawal
MELK (human) PVRLRLssFsCGQAs S336-p
MELK (mouse) PARLQLLSFSCGTAS S336
MELK (rat) under review -
S338-p
RLRLssFsCGQAsAt
0 2
MELK (human) RLRLssFsCGQAsAt S338-p
MELK (mouse) RLQLLSFSCGTASTT S338
MELK (rat) under review -
S343-p
sFsCGQAsAtPFtDI
Upstream
1 2
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
MELK (human) sFsCGQAsAtPFtDI S343-p
MELK (mouse) SFSCGTASTTPKSKN S343
MELK (rat) under review -
T345-p
sCGQAsAtPFtDIKS
Upstream
0 3
Treatment
  • BI2536
MELK (human) sCGQAsAtPFtDIKS T345-p
MELK (mouse) SCGTASTTPKSKNLs T345
MELK (rat) under review -
T348-p
QAsAtPFtDIKSNNW
0 1
MELK (human) QAsAtPFtDIKSNNW T348-p
MELK (mouse) gap -
MELK (rat) under review -
S356-p
DIKSNNWsLEDVTAs
Upstream
1 25
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
Treatment
  • MG132
  • MG132_withdrawal
MELK (human) DIKSNNWsLEDVTAs S356-p
MELK (mouse) TPKSKNLsLEDMsts S352-p
MELK (rat) under review -
T361
NWsLEDVTAsDKNyV
0 1
MELK (human) NWsLEDVTAsDKNyV T361
MELK (mouse) NLsLEDMstsDDNCV S357-p
MELK (rat) under review -
A362
WsLEDVTAsDKNyVA
0 1
MELK (human) WsLEDVTAsDKNyVA A362
MELK (mouse) LsLEDMstsDDNCVA T358-p
MELK (rat) under review -
S363-p
sLEDVTAsDKNyVAG
0 2
MELK (human) sLEDVTAsDKNyVAG S363-p
MELK (mouse) sLEDMstsDDNCVAG S359-p
MELK (rat) under review -
Y367-p
VTAsDKNyVAGLIDY
Upstream
0 1
Putative in vivo kinases:
  • MELK (human)
MELK (human) VTAsDKNyVAGLIDY Y367-p
MELK (mouse) MstsDDNCVAGLIDy C363
MELK (rat) under review -
Y374
yVAGLIDYDWCEDDL
0 1
MELK (human) yVAGLIDYDWCEDDL Y374
MELK (mouse) CVAGLIDyELCEDKL Y370-p
MELK (rat) under review -
T387-p
DLSTGAAtPRTsQFT
Upstream
0 1
Putative in vivo kinases:
  • MELK (human)
MELK (human) DLSTGAAtPRTsQFT T387-p
MELK (mouse) LCEDKLLAPKtPQVT A379
MELK (rat) under review -
T390
TGAAtPRTsQFTkyW
0 1
MELK (human) TGAAtPRTsQFTkyW T390
MELK (mouse) DKLLAPKtPQVTKHL T382-p
MELK (rat) under review -
S391-p
GAAtPRTsQFTkyWt
Upstream
1 0
Kinase, in vitro:
  • MELK (human)
MELK (human) GAAtPRTsQFTkyWt S391-p
MELK (mouse) KLLAPKtPQVTKHLA P383
MELK (rat) under review -
K395-ub
PRTsQFTkyWtEsNG
0 5
MELK (human) PRTsQFTkyWtEsNG K395-ub
MELK (mouse) PKtPQVTKHLAESNH K387
MELK (rat) under review -
Y396-p
RTsQFTkyWtEsNGV
0 1
MELK (human) RTsQFTkyWtEsNGV Y396-p
MELK (mouse) KtPQVTKHLAESNHA H388
MELK (rat) under review -
T398-p
sQFTkyWtEsNGVEs
Upstream
1 1
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
MELK (human) sQFTkyWtEsNGVEs T398-p
MELK (mouse) PQVTKHLAESNHAAs A390
MELK (rat) under review -
S400-p
FTkyWtEsNGVEsks
0 1
MELK (human) FTkyWtEsNGVEsks S400-p
MELK (mouse) VTKHLAESNHAAsKs S392
MELK (rat) under review -
S405-p
tEsNGVEsksLtPAL
Upstream
0 2
Putative in vivo kinases:
  • MELK (human)
MELK (human) tEsNGVEsksLtPAL S405-p
MELK (mouse) AESNHAAsKsPAPGV S397-p
MELK (rat) under review -
K406-ub
EsNGVEsksLtPALC
0 3
MELK (human) EsNGVEsksLtPALC K406-ub
MELK (mouse) ESNHAAsKsPAPGVR K398
MELK (rat) under review -
K406-sm
EsNGVEsksLtPALC
0 1
MELK (human) EsNGVEsksLtPALC K406-sm
MELK (mouse) ESNHAAsKsPAPGVR K398
MELK (rat) under review -
S407-p
sNGVEsksLtPALCR
Upstream
1 4
Kinase, in vitro:
  • MELK (human)
MELK (human) sNGVEsksLtPALCR S407-p
MELK (mouse) SNHAAsKsPAPGVRR S399-p
MELK (rat) under review -
T409-p
GVEsksLtPALCRtP
Upstream
0 7
Putative in vivo kinases:
  • MELK (human)
MELK (human) GVEsksLtPALCRtP T409-p
MELK (mouse) HAAsKsPAPGVRRAV A401
MELK (rat) under review -
T415-p
LtPALCRtPANKLKN
0 7
MELK (human) LtPALCRtPANKLKN T415-p
MELK (mouse) PAPGVRRAVANKLMD A407
MELK (rat) under review -
K423-ub
PANKLKNkENVytPK
0 1
MELK (human) PANKLKNkENVytPK K423-ub
MELK (mouse) VANKLMDKENVCTPK K415
MELK (rat) under review -
Y427-p
LKNkENVytPKsAVk
0 29
MELK (human) LKNkENVytPKsAVk Y427-p
MELK (mouse) LMDKENVCTPKSsVK C419
MELK (rat) under review -
T428-p
KNkENVytPKsAVkN
Upstream
0 7
Treatment
  • ischemia
MELK (human) KNkENVytPKsAVkN T428-p
MELK (mouse) MDKENVCTPKSsVKN T420
MELK (rat) under review -
S431-p
ENVytPKsAVkNEEy
Upstream
1 5
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
MELK (human) ENVytPKsAVkNEEy S431-p
MELK (mouse) ENVCTPKSsVKNEEQ S423
MELK (rat) under review -
A432
NVytPKsAVkNEEyF
0 1
MELK (human) NVytPKsAVkNEEyF A432
MELK (mouse) NVCTPKSsVKNEEQF S424-p
MELK (rat) under review -
K434-ub
ytPKsAVkNEEyFMF
0 1
MELK (human) ytPKsAVkNEEyFMF K434-ub
MELK (mouse) CTPKSsVKNEEQFVF K426
MELK (rat) under review -
K434-sm
ytPKsAVkNEEyFMF
0 1
MELK (human) ytPKsAVkNEEyFMF K434-sm
MELK (mouse) CTPKSsVKNEEQFVF K426
MELK (rat) under review -
Y438-p
sAVkNEEyFMFPEPK
Upstream
0 216
Putative in vivo kinases:
  • MELK (human)
Treatment
  • ephrin_B1
  • erlotinib
  • Su11274
MELK (human) sAVkNEEyFMFPEPK Y438-p
MELK (mouse) SsVKNEEQFVFsEPK Q430
MELK (rat) under review -
P442
NEEyFMFPEPKtPVN
0 1
MELK (human) NEEyFMFPEPKtPVN P442
MELK (mouse) NEEQFVFsEPKIPVS S434-p
MELK (rat) under review -
T446-p
FMFPEPKtPVNKNQH
0 40
MELK (human) FMFPEPKtPVNKNQH T446-p
MELK (mouse) FVFsEPKIPVSKNQY I438
MELK (rat) under review -
T459-p
QHKREILttPNrYTt
0 4
MELK (human) QHKREILttPNrYTt T459-p
MELK (mouse) QYKREIPAsPtRFPT A451
MELK (rat) under review -
T460-p
HKREILttPNrYTtP
Upstream
0 14
Treatment
  • MG132_withdrawal
  • nocodazole
  • thymidine
MELK (human) HKREILttPNrYTtP T460-p
MELK (mouse) YKREIPAsPtRFPTP S452-p
MELK (rat) under review -
N462
REILttPNrYTtPsk
0 1
MELK (human) REILttPNrYTtPsk N462
MELK (mouse) REIPAsPtRFPTPAK T454-p
MELK (rat) under review -
R463-m1
EILttPNrYTtPskA
0 1
MELK (human) EILttPNrYTtPskA R463-m1
MELK (mouse) EIPAsPtRFPTPAKA R455
MELK (rat) under review -
T466-p
ttPNrYTtPskARNQ
Upstream
0 3
Treatment
  • CXCL12
MELK (human) ttPNrYTtPskARNQ T466-p
MELK (mouse) AsPtRFPTPAKARAQ T458
MELK (rat) under review -
S468-p
PNrYTtPskARNQCL
0 1
MELK (human) PNrYTtPskARNQCL S468-p
MELK (mouse) PtRFPTPAKARAQCL A460
MELK (rat) under review -
K469-ub
NrYTtPskARNQCLk
0 1
MELK (human) NrYTtPskARNQCLk K469-ub
MELK (mouse) tRFPTPAKARAQCLR K461
MELK (rat) under review -
K476-ub
kARNQCLkEtPIkIP
0 1
MELK (human) kARNQCLkEtPIkIP K476-ub
MELK (mouse) KARAQCLREAPVRTP R468
MELK (rat) under review -
T478-p
RNQCLkEtPIkIPVN
Upstream
Downstream
1 12
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • translation, altered
Treatment
  • MG132_withdrawal
  • MLN8054
  • nocodazole
  • thymidine
MELK (human) RNQCLkEtPIkIPVN T478-p
MELK (mouse) RAQCLREAPVRTPGN A470
MELK (rat) under review -
K481-ub
CLkEtPIkIPVNsTG
0 3
MELK (human) CLkEtPIkIPVNsTG K481-ub
MELK (mouse) CLREAPVRTPGNSAG R473
MELK (rat) under review -
S486-p
PIkIPVNsTGtDkLM
0 2
MELK (human) PIkIPVNsTGtDkLM S486-p
MELK (mouse) PVRTPGNSAGADTLT S478
MELK (rat) under review -
T489-p
IPVNsTGtDkLMtGV
0 1
MELK (human) IPVNsTGtDkLMtGV T489-p
MELK (mouse) TPGNSAGADTLTTGV A481
MELK (rat) under review -
K491-ub
VNsTGtDkLMtGVIs
0 3
MELK (human) VNsTGtDkLMtGVIs K491-ub
MELK (mouse) GNSAGADTLTTGVIs T483
MELK (rat) under review -
T494-p
TGtDkLMtGVIsPER
Upstream
1 3
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
MELK (human) TGtDkLMtGVIsPER T494-p
MELK (mouse) AGADTLTTGVIsPER T486
MELK (rat) under review -
S498-p
kLMtGVIsPERRCRs
Upstream
0 22
Treatment
  • nocodazole
  • thymidine
MELK (human) kLMtGVIsPERRCRs S498-p
MELK (mouse) TLTTGVIsPERRCRs S490-p
MELK (rat) under review -
S505-p
sPERRCRsVELDLNQ
Upstream
1 33
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
Treatment
  • EGF
  • metastatic potential
MELK (human) sPERRCRsVELDLNQ S505-p
MELK (mouse) sPERRCRsMDVDLNQ S497-p
MELK (rat) under review -
T518-p
NQAHMEEtPkRKGAk
0 7
MELK (human) NQAHMEEtPkRKGAk T518-p
MELK (mouse) NQAHMEDTPKKKGTN T510
MELK (rat) under review -
K520-ub
AHMEEtPkRKGAkVF
0 1
MELK (human) AHMEEtPkRKGAkVF K520-ub
MELK (mouse) AHMEDTPKKKGTNVF K512
MELK (rat) under review -
K525-ub
tPkRKGAkVFGsLER
0 2
MELK (human) tPkRKGAkVFGsLER K525-ub
MELK (mouse) TPKKKGTNVFGsLER N517
MELK (rat) under review -
K525-sm
tPkRKGAkVFGsLER
0 1
MELK (human) tPkRKGAkVFGsLER K525-sm
MELK (mouse) TPKKKGTNVFGsLER N517
MELK (rat) under review -
S529-p
KGAkVFGsLERGLDk
Upstream
1 48
Kinase, in vitro:
  • MELK (human)
Putative in vivo kinases:
  • MELK (human)
Treatment
  • MG132_withdrawal
MELK (human) KGAkVFGsLERGLDk S529-p
MELK (mouse) KGTNVFGsLERGLDK S521-p
MELK (rat) under review -
K536-ub
sLERGLDkVItVLtR
0 5
MELK (human) sLERGLDkVItVLtR K536-ub
MELK (mouse) sLERGLDKVLTALTR K528
MELK (rat) under review -
T539-p
RGLDkVItVLtRsKR
Upstream
1 1
Kinase, in vitro:
  • MELK (human)
MELK (human) RGLDkVItVLtRsKR T539-p
MELK (mouse) RGLDKVLTALTRNKK T531
MELK (rat) under review -
T542-p
DkVItVLtRsKRKGS
0 4
MELK (human) DkVItVLtRsKRKGS T542-p
MELK (mouse) DKVLTALTRNKKKGS T534
MELK (rat) under review -
S544-p
VItVLtRsKRKGSAR
0 3
MELK (human) VItVLtRsKRKGSAR S544-p
MELK (mouse) VLTALTRNKKKGSAR N536
MELK (rat) under review -
K558-ub
RDGPRRLkLHYNVTT
0 1
MELK (human) RDGPRRLkLHYNVTT K558-ub
MELK (mouse) RDGPRKRKLHyNVTT K550
MELK (rat) under review -
Y561
PRRLkLHYNVTTTRL
0 1
MELK (human) PRRLkLHYNVTTTRL Y561
MELK (mouse) PRKRKLHyNVTTTRL Y553-p
MELK (rat) under review -
K585-ub
IMSILPKkHVDFVQk
0 2
MELK (human) IMSILPKkHVDFVQk K585-ub
MELK (mouse) IMAILPKKNVDFVQK K577
MELK (rat) under review -
K592-ub
kHVDFVQkGYTLkCQ
0 2
MELK (human) kHVDFVQkGYTLkCQ K592-ub
MELK (mouse) KNVDFVQKGYTLKCQ K584
MELK (rat) under review -
K597-ub
VQkGYTLkCQTQSDF
0 2
MELK (human) VQkGYTLkCQTQSDF K597-ub
MELK (mouse) VQKGYTLKCQTQSDF K589
MELK (rat) under review -
K632-ub
GIRRQRLkGDAWVYk
0 2
MELK (human) GIRRQRLkGDAWVYk K632-ub
MELK (mouse) GIRRQRLKGDAWVYK K624
MELK (rat) under review -
K639-ub
kGDAWVYkRLVEDIL
0 2
MELK (human) kGDAWVYkRLVEDIL K639-ub
MELK (mouse) KGDAWVYKRLVEDIL K631
MELK (rat) under review -
K639-m3
kGDAWVYkRLVEDIL
0 1
MELK (human) kGDAWVYkRLVEDIL K639-m3
MELK (mouse) KGDAWVYKRLVEDIL K631
MELK (rat) under review -
K650-ub
EDILSSCkV______
0 6
MELK (human) EDILSSCkV______ K650-ub
MELK (mouse) EDILSGCKM______ K642
MELK (rat) under review -
K650-m3
EDILSSCkV______
0 1
MELK (human) EDILSSCkV______ K650-m3
MELK (mouse) EDILSGCKM______ K642
MELK (rat) under review -