Other Species / Isoforms
  Ku70 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsGWEsyyk
0 7
Ku70 (human) ______MsGWEsyyk S2-p
Ku70 (mouse) ______MSEWEsYYK S2
Ku70 (rat) ______MSEWESYYK S2
S6-p
__MsGWEsyykTEGD
Upstream
3 7
Kinase, in vitro:
  • DNAPK (human)
Treatment
  • okadaic_acid
Ku70 (human) __MsGWEsyykTEGD S6-p
Ku70 (mouse) __MSEWEsYYKTEGE S6-p
Ku70 (rat) __MSEWESYYKTEGE S6
Y7-p
_MsGWEsyykTEGDE
0 1
Ku70 (human) _MsGWEsyykTEGDE Y7-p
Ku70 (mouse) _MSEWEsYYKTEGEE Y7
Ku70 (rat) _MSEWESYYKTEGEE Y7
Y8-p
MsGWEsyykTEGDEE
0 1
Ku70 (human) MsGWEsyykTEGDEE Y8-p
Ku70 (mouse) MSEWEsYYKTEGEEE Y8
Ku70 (rat) MSEWESYYKTEGEEE Y8
K9-sm
sGWEsyykTEGDEEA
0 2
Ku70 (human) sGWEsyykTEGDEEA K9-sm
Ku70 (mouse) SEWEsYYKTEGEEEE K9
Ku70 (rat) SEWESYYKTEGEEEE K9
S27-p
QEENLEAsGDykYsG
Upstream
Downstream
1 13
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, inhibited
  • cell cycle regulation
Putative in vivo kinases:
  • ATM (human)
  • DNAPK (human)
Treatment
  • ionizing_radiation
Ku70 (human) QEENLEAsGDykYsG S27-p
Ku70 (mouse) EEESPDTGGEYkYSG G25
Ku70 (rat) EEQSPDTNGEYKYSG N25
Y30-p
NLEAsGDykYsGRDs
0 2
Ku70 (human) NLEAsGDykYsGRDs Y30-p
Ku70 (mouse) SPDTGGEYkYSGRDS Y28
Ku70 (rat) SPDTNGEYKYSGRDS Y28
K31-ac
LEAsGDykYsGRDsL
0 2
Ku70 (human) LEAsGDykYsGRDsL K31-ac
Ku70 (mouse) PDTGGEYkYSGRDSL K29-ac
Ku70 (rat) PDTNGEYKYSGRDSL K29
K31-ub
LEAsGDykYsGRDsL
0 3
Ku70 (human) LEAsGDykYsGRDsL K31-ub
Ku70 (mouse) PDTGGEYKYSGRDSL K29
Ku70 (rat) PDTNGEYKYSGRDSL K29
K31-sm
LEAsGDykYsGRDsL
0 2
Ku70 (human) LEAsGDykYsGRDsL K31-sm
Ku70 (mouse) PDTGGEYKYSGRDSL K29
Ku70 (rat) PDTNGEYKYSGRDSL K29
S33-p
AsGDykYsGRDsLIF
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, inhibited
  • cell cycle regulation
Putative in vivo kinases:
  • ATM (human)
  • DNAPK (human)
Ku70 (human) AsGDykYsGRDsLIF S33-p
Ku70 (mouse) TGGEYkYSGRDSLIF S31
Ku70 (rat) TNGEYKYSGRDSLIF S31
S37-p
ykYsGRDsLIFLVDA
0 1
Ku70 (human) ykYsGRDsLIFLVDA S37-p
Ku70 (mouse) YkYSGRDSLIFLVDA S35
Ku70 (rat) YKYSGRDSLIFLVDA S35
S45-p
LIFLVDAsKAMFEsQ
0 1
Ku70 (human) LIFLVDAsKAMFEsQ S45-p
Ku70 (mouse) LIFLVDASRAMFEsQ S43
Ku70 (rat) LIFLVDASRAMFESQ S43
S51-p
AsKAMFEsQsEDELT
Upstream
2 0
Kinase, in vitro:
  • DNAPK (human)
Ku70 (human) AsKAMFEsQsEDELT S51-p
Ku70 (mouse) ASRAMFEsQGEDELT S49-p
Ku70 (rat) ASRAMFESQGEDELT S49
S53-p
KAMFEsQsEDELTPF
0 1
Ku70 (human) KAMFEsQsEDELTPF S53-p
Ku70 (mouse) RAMFEsQGEDELTPF G51
Ku70 (rat) RAMFESQGEDELTPF G51
K92-ac
VVFYGTEkDkNSVNF
0 1
Ku70 (human) VVFYGTEkDkNSVNF K92-ac
Ku70 (mouse) VVFYGTEKDKNSVNF K90
Ku70 (rat) VVFYGTEKDKNSVNF K90
K92-ub
VVFYGTEkDkNSVNF
0 2
Ku70 (human) VVFYGTEkDkNSVNF K92-ub
Ku70 (mouse) VVFYGTEKDKNSVNF K90
Ku70 (rat) VVFYGTEKDKNSVNF K90
K92-m1
VVFYGTEkDkNSVNF
0 1
Ku70 (human) VVFYGTEkDkNSVNF K92-m1
Ku70 (mouse) VVFYGTEKDKNSVNF K90
Ku70 (rat) VVFYGTEKDKNSVNF K90
K94-ub
FYGTEkDkNSVNFkN
0 3
Ku70 (human) FYGTEkDkNSVNFkN K94-ub
Ku70 (mouse) FYGTEKDKNSVNFKN K92
Ku70 (rat) FYGTEKDKNSVNFKS K92
K100-ac
DkNSVNFkNIyVLQE
0 1
Ku70 (human) DkNSVNFkNIyVLQE K100-ac
Ku70 (mouse) DKNSVNFKNIYVLQD K98
Ku70 (rat) DKNSVNFKSIYVLQD K98
K100-ub
DkNSVNFkNIyVLQE
0 8
Ku70 (human) DkNSVNFkNIyVLQE K100-ub
Ku70 (mouse) DKNSVNFKNIYVLQD K98
Ku70 (rat) DKNSVNFKSIYVLQD K98
K100-sc
DkNSVNFkNIyVLQE
0 1
Ku70 (human) DkNSVNFkNIyVLQE K100-sc
Ku70 (mouse) DKNSVNFKNIYVLQD K98
Ku70 (rat) DKNSVNFKSIYVLQD K98
Y103-p
SVNFkNIyVLQELDN
0 10
Ku70 (human) SVNFkNIyVLQELDN Y103-p
Ku70 (mouse) SVNFKNIYVLQDLDN Y101
Ku70 (rat) SVNFKSIYVLQDLDN Y101
K114-ac
ELDNPGAkRILELDQ
0 13
Ku70 (human) ELDNPGAkRILELDQ K114-ac
Ku70 (mouse) DLDNPGAKRVLELDQ K112
Ku70 (rat) DLDNPGAKRVLELDR K112
K114-ub
ELDNPGAkRILELDQ
0 23
Ku70 (human) ELDNPGAkRILELDQ K114-ub
Ku70 (mouse) DLDNPGAKRVLELDQ K112
Ku70 (rat) DLDNPGAKRVLELDR K112
K114-m1
ELDNPGAkRILELDQ
0 1
Ku70 (human) ELDNPGAkRILELDQ K114-m1
Ku70 (mouse) DLDNPGAKRVLELDQ K112
Ku70 (rat) DLDNPGAKRVLELDR K112
K114-sc
ELDNPGAkRILELDQ
0 1
Ku70 (human) ELDNPGAkRILELDQ K114-sc
Ku70 (mouse) DLDNPGAKRVLELDQ K112
Ku70 (rat) DLDNPGAKRVLELDR K112
K123-ac
ILELDQFkGQQGQkR
0 3
Ku70 (human) ILELDQFkGQQGQkR K123-ac
Ku70 (mouse) VLELDQFKGQQGKKH K121
Ku70 (rat) VLELDRFKGQQGKKH K121
K123-ub
ILELDQFkGQQGQkR
0 7
Ku70 (human) ILELDQFkGQQGQkR K123-ub
Ku70 (mouse) VLELDQFKGQQGKKH K121
Ku70 (rat) VLELDRFKGQQGKKH K121
K123-sm
ILELDQFkGQQGQkR
0 2
Ku70 (human) ILELDQFkGQQGQkR K123-sm
Ku70 (mouse) VLELDQFKGQQGKKH K121
Ku70 (rat) VLELDRFKGQQGKKH K121
K123-m1
ILELDQFkGQQGQkR
0 1
Ku70 (human) ILELDQFkGQQGQkR K123-m1
Ku70 (mouse) VLELDQFKGQQGKKH K121
Ku70 (rat) VLELDRFKGQQGKKH K121
K123-sc
ILELDQFkGQQGQkR
0 1
Ku70 (human) ILELDQFkGQQGQkR K123-sc
Ku70 (mouse) VLELDQFKGQQGKKH K121
Ku70 (rat) VLELDRFKGQQGKKH K121
K129-ub
FkGQQGQkRFQDMMG
0 3
Ku70 (human) FkGQQGQkRFQDMMG K129-ub
Ku70 (mouse) FKGQQGKKHFRDTVG K127
Ku70 (rat) FKGQQGKKHFRDTIG K127
S155-p
WVCANLFsDVQFKMS
Upstream
Downstream
2 0
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
Treatment
  • ionizing_radiation
Ku70 (human) WVCANLFsDVQFKMS S155-p
Ku70 (mouse) WVCANLFSDVQLKMS S153
Ku70 (rat) WVCANLFSDVQFKMS S153
S180-p
DNPHGNDsAkASRAR
0 4
Ku70 (human) DNPHGNDsAkASRAR S180-p
Ku70 (mouse) DDPHGRDSAKASRAR S178
Ku70 (rat) DDPHGNDSAKASRAR S178
K182-ub
PHGNDsAkASRARTk
0 3
Ku70 (human) PHGNDsAkASRARTk K182-ub
Ku70 (mouse) PHGRDSAKASRARTK K180
Ku70 (rat) PHGNDSAKASRARTK K180
K189-ub
kASRARTkAGDLrDT
0 1
Ku70 (human) kASRARTkAGDLrDT K189-ub
Ku70 (mouse) KASRARTKASDLRDT K187
Ku70 (rat) KASRARTKASDLRDT K187
R194-m1
RTkAGDLrDTGIFLD
0 1
Ku70 (human) RTkAGDLrDTGIFLD R194-m1
Ku70 (mouse) RTKASDLRDTGIFLD R192
Ku70 (rat) RTKASDLRDTGIFLD R192
K206-ub
FLDLMHLkkPGGFDI
0 1
Ku70 (human) FLDLMHLkkPGGFDI K206-ub
Ku70 (mouse) FLDLMHLKKPGGFDV K204
Ku70 (rat) FLDLMHLKKRGGFDV K204
K207-ub
LDLMHLkkPGGFDIS
0 1
Ku70 (human) LDLMHLkkPGGFDIS K207-ub
Ku70 (mouse) LDLMHLKKPGGFDVS K205
Ku70 (rat) LDLMHLKKRGGFDVS K205
K207-m1
LDLMHLkkPGGFDIS
0 1
Ku70 (human) LDLMHLkkPGGFDIS K207-m1
Ku70 (mouse) LDLMHLKKPGGFDVS K205
Ku70 (rat) LDLMHLKKRGGFDVS K205
S222-p
LFYRDIIsIAEDEDL
0 2
Ku70 (human) LFYRDIIsIAEDEDL S222-p
Ku70 (mouse) VFYRDIITTAEDEDL T220
Ku70 (rat) LFYRDIISIAEDEDL S220
R230-m1
IAEDEDLrVHFEESs
0 1
Ku70 (human) IAEDEDLrVHFEESs R230-m1
Ku70 (mouse) TAEDEDLGVHFEESS G228
Ku70 (rat) IAEDEDLGVHFEESS G228
S237-p
rVHFEESskLEDLLr
0 2
Ku70 (human) rVHFEESskLEDLLr S237-p
Ku70 (mouse) GVHFEESSKLEDLLR S235
Ku70 (rat) GVHFEESSKLEDLLR S235
K238-ub
VHFEESskLEDLLrK
0 6
Ku70 (human) VHFEESskLEDLLrK K238-ub
Ku70 (mouse) VHFEESSKLEDLLRK K236
Ku70 (rat) VHFEESSKLEDLLRK K236
R244-m1
skLEDLLrKVRAKET
0 1
Ku70 (human) skLEDLLrKVRAKET R244-m1
Ku70 (mouse) SKLEDLLRKVRAKET R242
Ku70 (rat) SKLEDLLRKVRAKET R242
K265-ub
RLKLKLNkDIVISVG
0 1
Ku70 (human) RLKLKLNkDIVISVG K265-ub
Ku70 (mouse) RLKFKLGEDVVLMVG E263
Ku70 (rat) RLKFKLGKDVALMVG K263
K282-ac
NLVQKALkPPPIkLY
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, inhibited
Ku70 (human) NLVQKALkPPPIkLY K282-ac
Ku70 (mouse) NLVQKANKPFPVRLY K280
Ku70 (rat) NLVQKANKPFPVRLY K280
K282-ub
NLVQKALkPPPIkLY
0 4
Ku70 (human) NLVQKALkPPPIkLY K282-ub
Ku70 (mouse) NLVQKANKPFPVRLY K280
Ku70 (rat) NLVQKANKPFPVRLY K280
K287-ac
ALkPPPIkLYREtNE
0 4
Ku70 (human) ALkPPPIkLYREtNE K287-ac
Ku70 (mouse) ANKPFPVRLYRETNE R285
Ku70 (rat) ANKPFPVRLYRETNE R285
K287-ub
ALkPPPIkLYREtNE
0 8
Ku70 (human) ALkPPPIkLYREtNE K287-ub
Ku70 (mouse) ANKPFPVRLYRETNE R285
Ku70 (rat) ANKPFPVRLYRETNE R285
K287-sm
ALkPPPIkLYREtNE
0 1
Ku70 (human) ALkPPPIkLYREtNE K287-sm
Ku70 (mouse) ANKPFPVRLYRETNE R285
Ku70 (rat) ANKPFPVRLYRETNE R285
T292-p
PIkLYREtNEPVkTk
0 1
Ku70 (human) PIkLYREtNEPVkTk T292-p
Ku70 (mouse) PVRLYRETNEPVKTK T290
Ku70 (rat) PVRLYRETNEPVKTK T290
K297-ub
REtNEPVkTkTrtFN
0 3
Ku70 (human) REtNEPVkTkTrtFN K297-ub
Ku70 (mouse) RETNEPVKTKTRTFN K295
Ku70 (rat) RETNEPVKTKTRTFN K295
K297-sm
REtNEPVkTkTrtFN
0 2
Ku70 (human) REtNEPVkTkTrtFN K297-sm
Ku70 (mouse) RETNEPVKTKTRTFN K295
Ku70 (rat) RETNEPVKTKTRTFN K295
K299-ub
tNEPVkTkTrtFNTs
0 2
Ku70 (human) tNEPVkTkTrtFNTs K299-ub
Ku70 (mouse) TNEPVKTKTRTFNVN K297
Ku70 (rat) TNEPVKTKTRTFNVN K297
R301-m1
EPVkTkTrtFNTsTG
0 1
Ku70 (human) EPVkTkTrtFNTsTG R301-m1
Ku70 (mouse) EPVKTKTRTFNVNTG R299
Ku70 (rat) EPVKTKTRTFNVNTG R299
T302-p
PVkTkTrtFNTsTGG
0 2
Ku70 (human) PVkTkTrtFNTsTGG T302-p
Ku70 (mouse) PVKTKTRTFNVNTGS T300
Ku70 (rat) PVKTKTRTFNVNTGS T300
S306-p
kTrtFNTsTGGLLLP
0 4
Ku70 (human) kTrtFNTsTGGLLLP S306-p
Ku70 (mouse) KTRTFNVNTGSLLLP N304
Ku70 (rat) KTRTFNVNTGSLLLP N304
S314-p
TGGLLLPsDTkrsQI
0 1
Ku70 (human) TGGLLLPsDTkrsQI S314-p
Ku70 (mouse) TGSLLLPSDTKRSLT S312
Ku70 (rat) TGSLLLPSDTKRSLT S312
K317-ac
LLLPsDTkrsQIyGs
3 49
Ku70 (human) LLLPsDTkrsQIyGs K317-ac
Ku70 (mouse) LLLPSDTKRSLTYGT K315
Ku70 (rat) LLLPSDTKRSLTFGT K315
K317-ub
LLLPsDTkrsQIyGs
Upstream
0 41
Treatment
  • MG132
Ku70 (human) LLLPsDTkrsQIyGs K317-ub
Ku70 (mouse) LLLPSDTKRSLTYGT K315
Ku70 (rat) LLLPSDTKRSLTFGT K315
K317-sm
LLLPsDTkrsQIyGs
0 1
Ku70 (human) LLLPsDTkrsQIyGs K317-sm
Ku70 (mouse) LLLPSDTKRSLTYGT K315
Ku70 (rat) LLLPSDTKRSLTFGT K315
R318-m1
LLPsDTkrsQIyGsR
0 1
Ku70 (human) LLPsDTkrsQIyGsR R318-m1
Ku70 (mouse) LLPSDTKRSLTYGTR R316
Ku70 (rat) LLPSDTKRSLTFGTR R316
S319-p
LPsDTkrsQIyGsRQ
0 15
Ku70 (human) LPsDTkrsQIyGsRQ S319-p
Ku70 (mouse) LPSDTKRSLTYGTRQ S317
Ku70 (rat) LPSDTKRSLTFGTRQ S317
Y322-p
DTkrsQIyGsRQIIL
0 5
Ku70 (human) DTkrsQIyGsRQIIL Y322-p
Ku70 (mouse) DTKRSLTYGTRQIVL Y320
Ku70 (rat) DTKRSLTFGTRQIVL F320
S324-p
krsQIyGsRQIILEk
0 6
Ku70 (human) krsQIyGsRQIILEk S324-p
Ku70 (mouse) KRSLTYGTRQIVLEK T322
Ku70 (rat) KRSLTFGTRQIVLEK T322
K331-ac
sRQIILEkEETEELk
3 5
Ku70 (human) sRQIILEkEETEELk K331-ac
Ku70 (mouse) TRQIVLEKEETEELK K329
Ku70 (rat) TRQIVLEKEETEELK K329
K331-ub
sRQIILEkEETEELk
0 6
Ku70 (human) sRQIILEkEETEELk K331-ub
Ku70 (mouse) TRQIVLEKEETEELK K329
Ku70 (rat) TRQIVLEKEETEELK K329
K331-sm
sRQIILEkEETEELk
0 1
Ku70 (human) sRQIILEkEETEELk K331-sm
Ku70 (mouse) TRQIVLEKEETEELK K329
Ku70 (rat) TRQIVLEKEETEELK K329
K331-sc
sRQIILEkEETEELk
0 1
Ku70 (human) sRQIILEkEETEELk K331-sc
Ku70 (mouse) TRQIVLEKEETEELK K329
Ku70 (rat) TRQIVLEKEETEELK K329
K338-ac
kEETEELkRFDDPGL
Downstream
3 5
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, inhibited
Ku70 (human) kEETEELkRFDDPGL K338-ac
Ku70 (mouse) KEETEELKRFDEPGL K336
Ku70 (rat) KEETEELKRFDEPGL K336
K338-ub
kEETEELkRFDDPGL
0 22
Ku70 (human) kEETEELkRFDDPGL K338-ub
Ku70 (mouse) KEETEELKRFDEPGL K336
Ku70 (rat) KEETEELKRFDEPGL K336
K338-sm
kEETEELkRFDDPGL
0 1
Ku70 (human) kEETEELkRFDDPGL K338-sm
Ku70 (mouse) KEETEELKRFDEPGL K336
Ku70 (rat) KEETEELKRFDEPGL K336
K351-ub
GLMLMGFkPLVLLkk
0 13
Ku70 (human) GLMLMGFkPLVLLkk K351-ub
Ku70 (mouse) GLILMGFKPTVMLKK K349
Ku70 (rat) GLILMGFKPMVMLKN K349
K357-ub
FkPLVLLkkHHYLRP
0 8
Ku70 (human) FkPLVLLkkHHYLRP K357-ub
Ku70 (mouse) FKPTVMLKKQHYLRP K355
Ku70 (rat) FKPMVMLKNHHYLRP K355
K357-sc
FkPLVLLkkHHYLRP
0 1
Ku70 (human) FkPLVLLkkHHYLRP K357-sc
Ku70 (mouse) FKPTVMLKKQHYLRP K355
Ku70 (rat) FKPMVMLKNHHYLRP K355
K358-ub
kPLVLLkkHHYLRPS
0 23
Ku70 (human) kPLVLLkkHHYLRPS K358-ub
Ku70 (mouse) KPTVMLKKQHYLRPS K356
Ku70 (rat) KPMVMLKNHHYLRPS N356
K392-ac
LLIKCLEkEVAALCR
0 2
Ku70 (human) LLIKCLEkEVAALCR K392-ac
Ku70 (mouse) LLTKCVEKKVIAVCR K390
Ku70 (rat) LLTKCVEKEVIAVCR K390
K392-ub
LLIKCLEkEVAALCR
0 2
Ku70 (human) LLIKCLEkEVAALCR K392-ub
Ku70 (mouse) LLTKCVEKKVIAVCR K390
Ku70 (rat) LLTKCVEKEVIAVCR K390
K424-sm
EEELDDQkIQVtPPG
0 2
Ku70 (human) EEELDDQkIQVtPPG K424-sm
Ku70 (mouse) EEELDDQNIQVTPGG N422
Ku70 (rat) EEELDDQNIQVTPAG N422
T428-p
DDQkIQVtPPGFQLV
0 1
Ku70 (human) DDQkIQVtPPGFQLV T428-p
Ku70 (mouse) DDQNIQVTPGGFQLV T426
Ku70 (rat) DDQNIQVTPAGFQLV T426
K443-ub
FLPFADDkRkMPFTE
0 5
Ku70 (human) FLPFADDkRkMPFTE K443-ub
Ku70 (mouse) FLPYADDKRKVPFTE K441
Ku70 (rat) FLPYADDKRKVPFTE K441
K443-sm
FLPFADDkRkMPFTE
0 2
Ku70 (human) FLPFADDkRkMPFTE K443-sm
Ku70 (mouse) FLPYADDKRKVPFTE K441
Ku70 (rat) FLPYADDKRKVPFTE K441
K445-ub
PFADDkRkMPFTEkI
0 4
Ku70 (human) PFADDkRkMPFTEkI K445-ub
Ku70 (mouse) PYADDKRKVPFTEKV K443
Ku70 (rat) PYADDKRKVPFTEKV K443
K451-ub
RkMPFTEkIMAtPEQ
Upstream
0 11
Treatment
  • MG132
Ku70 (human) RkMPFTEkIMAtPEQ K451-ub
Ku70 (mouse) RKVPFTEKVtANQEQ K449
Ku70 (rat) RKVPFTEKVMANPEQ K449
M453
MPFTEkIMAtPEQVG
0 1
Ku70 (human) MPFTEkIMAtPEQVG M453
Ku70 (mouse) VPFTEKVtANQEQID T451-p
Ku70 (rat) VPFTEKVMANPEQID M451
T455-p
FTEkIMAtPEQVGkM
Upstream
1 55
Kinase, in vitro:
  • CDK2 (human)
Treatment
  • EGF
  • ZK-Thiazolidinone
Ku70 (human) FTEkIMAtPEQVGkM T455-p
Ku70 (mouse) FTEKVtANQEQIDKM N453
Ku70 (rat) FTEKVMANPEQIDKM N453
K461-ac
AtPEQVGkMkAIVEk
0 12
Ku70 (human) AtPEQVGkMkAIVEk K461-ac
Ku70 (mouse) ANQEQIDKMKAIVQK K459
Ku70 (rat) ANPEQIDKMKAIVQK K459
K461-ub
AtPEQVGkMkAIVEk
0 12
Ku70 (human) AtPEQVGkMkAIVEk K461-ub
Ku70 (mouse) ANQEQIDKMKAIVQK K459
Ku70 (rat) ANPEQIDKMKAIVQK K459
K463-ub
PEQVGkMkAIVEkLR
0 4
Ku70 (human) PEQVGkMkAIVEkLR K463-ub
Ku70 (mouse) QEQIDKMKAIVQKLR K461
Ku70 (rat) PEQIDKMKAIVQKLR K461
K468-ac
kMkAIVEkLRFTYrs
0 13
Ku70 (human) kMkAIVEkLRFTYrs K468-ac
Ku70 (mouse) KMKAIVQKLRFTYRS K466
Ku70 (rat) KMKAIVQKLRFTYRS K466
K468-ub
kMkAIVEkLRFTYrs
0 6
Ku70 (human) kMkAIVEkLRFTYrs K468-ub
Ku70 (mouse) KMKAIVQKLRFTYRS K466
Ku70 (rat) KMKAIVQKLRFTYRS K466
R474-m1
EkLRFTYrsDsFENP
0 1
Ku70 (human) EkLRFTYrsDsFENP R474-m1
Ku70 (mouse) QKLRFTYRSDsFENP R472
Ku70 (rat) QKLRFTYRSDSFENP R472
S475-p
kLRFTYrsDsFENPV
0 2
Ku70 (human) kLRFTYrsDsFENPV S475-p
Ku70 (mouse) KLRFTYRSDsFENPV S473
Ku70 (rat) KLRFTYRSDSFENPV S473
S477-p
RFTYrsDsFENPVLQ
Upstream
0 19
Kinase, in vitro:
  • Chk1 (human)
Ku70 (human) RFTYrsDsFENPVLQ S477-p
Ku70 (mouse) RFTYRSDsFENPVLQ S475-p
Ku70 (rat) RFTYRSDSFENPVLQ S475
K510-sm
AVDLTLPkVEAMNkR
0 2
Ku70 (human) AVDLTLPkVEAMNkR K510-sm
Ku70 (mouse) VVDLTLPKVEAIKKR K508
Ku70 (rat) VVDLTLPKVEAIKKR K508
K516-ub
PkVEAMNkRLGsLVD
0 4
Ku70 (human) PkVEAMNkRLGsLVD K516-ub
Ku70 (mouse) PKVEAIKKRLGsLAD K514
Ku70 (rat) PKVEAIKKRLGSLAD K514
S520-p
AMNkRLGsLVDEFkE
Upstream
0 31
Regulatory protein:
  • PLK1 (human)
Ku70 (human) AMNkRLGsLVDEFkE S520-p
Ku70 (mouse) AIKKRLGsLADEFKE S518-p
Ku70 (rat) AIKKRLGSLADEFKE S518
K526-ac
GsLVDEFkELVyPPD
0 3
Ku70 (human) GsLVDEFkELVyPPD K526-ac
Ku70 (mouse) GsLADEFKELVYPPG K524
Ku70 (rat) GSLADEFKELVYPPG K524
K526-ub
GsLVDEFkELVyPPD
0 3
Ku70 (human) GsLVDEFkELVyPPD K526-ub
Ku70 (mouse) GsLADEFKELVYPPG K524
Ku70 (rat) GSLADEFKELVYPPG K524
K526-sm
GsLVDEFkELVyPPD
0 1
Ku70 (human) GsLVDEFkELVyPPD K526-sm
Ku70 (mouse) GsLADEFKELVYPPG K524
Ku70 (rat) GSLADEFKELVYPPG K524
Y530-p
DEFkELVyPPDyNPE
Upstream
Downstream
1 2
Effects on Biological Processes:
  • apoptosis, inhibited
Putative in vivo kinases:
  • Src (human)
Ku70 (human) DEFkELVyPPDyNPE Y530-p
Ku70 (mouse) DEFKELVYPPGYNPE Y528
Ku70 (rat) DEFKELVYPPGYNPE Y528
Y534-p
ELVyPPDyNPEGkVt
0 1
Ku70 (human) ELVyPPDyNPEGkVt Y534-p
Ku70 (mouse) ELVYPPGYNPEGKVA Y532
Ku70 (rat) ELVYPPGYNPEGKIA Y532
K539-ac
PDyNPEGkVtkRkHD
Upstream
Downstream
2 2
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Regulatory protein:
  • SIRT1 (human)
Treatment
  • resveratrol
Ku70 (human) PDyNPEGkVtkRkHD K539-ac
Ku70 (mouse) PGYNPEGKVAKRKQD K537
Ku70 (rat) PGYNPEGKIAKRKAD K537
K539-ub
PDyNPEGkVtkRkHD
0 2
Ku70 (human) PDyNPEGkVtkRkHD K539-ub
Ku70 (mouse) PGYNPEGKVAKRKQD K537
Ku70 (rat) PGYNPEGKIAKRKAD K537
K539-sm
PDyNPEGkVtkRkHD
0 1
Ku70 (human) PDyNPEGkVtkRkHD K539-sm
Ku70 (mouse) PGYNPEGKVAKRKQD K537
Ku70 (rat) PGYNPEGKIAKRKAD K537
T541-p
yNPEGkVtkRkHDNE
0 3
Ku70 (human) yNPEGkVtkRkHDNE T541-p
Ku70 (mouse) YNPEGKVAKRKQDDE A539
Ku70 (rat) YNPEGKIAKRKADNE A539
K542-ac
NPEGkVtkRkHDNEG
Upstream
Downstream
3 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • apoptosis, inhibited
  • cell growth, induced
Treatment
  • siRNA
Ku70 (human) NPEGkVtkRkHDNEG K542-ac
Ku70 (mouse) NPEGKVAKRKQDDEG K540
Ku70 (rat) NPEGKIAKRKADNEG K540
K544-ac
EGkVtkRkHDNEGsG
1 3
Ku70 (human) EGkVtkRkHDNEGsG K544-ac
Ku70 (mouse) EGKVAKRKQDDEGST K542
Ku70 (rat) EGKIAKRKADNEGSA K542
S550-p
RkHDNEGsGSkRPkV
Upstream
0 1
Treatment
  • nocodazole
Ku70 (human) RkHDNEGsGSkRPkV S550-p
Ku70 (mouse) RKQDDEGSTSKKPKV S548
Ku70 (rat) RKADNEGSASKKPKV S548
K553-ac
DNEGsGSkRPkVEYs
1 1
Ku70 (human) DNEGsGSkRPkVEYs K553-ac
Ku70 (mouse) DDEGSTSKKPKVELs K551
Ku70 (rat) DNEGSASKKPKVELs K551
K553-ub
DNEGsGSkRPkVEYs
0 1
Ku70 (human) DNEGsGSkRPkVEYs K553-ub
Ku70 (mouse) DDEGSTSKKPKVELs K551
Ku70 (rat) DNEGSASKKPKVELs K551
K556-ac
GsGSkRPkVEYsEEE
1 1
Ku70 (human) GsGSkRPkVEYsEEE K556-ac
Ku70 (mouse) GSTSKKPKVELsEEE K554
Ku70 (rat) GSASKKPKVELsEEE K554
K556-ub
GsGSkRPkVEYsEEE
0 4
Ku70 (human) GsGSkRPkVEYsEEE K556-ub
Ku70 (mouse) GSTSKKPKVELsEEE K554
Ku70 (rat) GSASKKPKVELsEEE K554
K556-sm
GsGSkRPkVEYsEEE
0 2
Ku70 (human) GsGSkRPkVEYsEEE K556-sm
Ku70 (mouse) GSTSKKPKVELsEEE K554
Ku70 (rat) GSASKKPKVELsEEE K554
S560-p
kRPkVEYsEEELkTH
Upstream
0 10
Regulatory protein:
  • PLK1 (human)
Ku70 (human) kRPkVEYsEEELkTH S560-p
Ku70 (mouse) KKPKVELsEEELKAH S558-p
Ku70 (rat) KKPKVELsEEELKDL S558-p
K565-ub
EYsEEELkTHISkGT
0 6
Ku70 (human) EYsEEELkTHISkGT K565-ub
Ku70 (mouse) ELsEEELKAHFRKGT K563
Ku70 (rat) ELsEEELKDLFAKGT K563
K570-ac
ELkTHISkGTLGkFt
0 1
Ku70 (human) ELkTHISkGTLGkFt K570-ac
Ku70 (mouse) ELKAHFRKGTLGKLT K568
Ku70 (rat) ELKDLFAKGTLGKLT K568
K570-ub
ELkTHISkGTLGkFt
0 4
Ku70 (human) ELkTHISkGTLGkFt K570-ub
Ku70 (mouse) ELKAHFRKGTLGKLT K568
Ku70 (rat) ELKDLFAKGTLGKLT K568
K575-ac
ISkGTLGkFtVPMLk
0 3
Ku70 (human) ISkGTLGkFtVPMLk K575-ac
Ku70 (mouse) FRKGTLGKLTVPTLK K573
Ku70 (rat) FAKGTLGKLTVPALR K573
K575-ub
ISkGTLGkFtVPMLk
0 6
Ku70 (human) ISkGTLGkFtVPMLk K575-ub
Ku70 (mouse) FRKGTLGKLTVPTLK K573
Ku70 (rat) FAKGTLGKLTVPALR K573
T577-p
kGTLGkFtVPMLkEA
0 1
Ku70 (human) kGTLGkFtVPMLkEA T577-p
Ku70 (mouse) KGTLGKLTVPTLKDI T575
Ku70 (rat) KGTLGKLTVPALRDI T575
K582-ub
kFtVPMLkEACRAyG
0 4
Ku70 (human) kFtVPMLkEACRAyG K582-ub
Ku70 (mouse) KLTVPTLKDICKAHG K580
Ku70 (rat) KLTVPALRDICKAYG R580
Y588-p
LkEACRAyGLksGLk
0 1
Ku70 (human) LkEACRAy