Other Species / Isoforms
  eIF2-alpha (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K12
SCRFYQHKFPEVEDV
0 1
eIF2-alpha (human) SCRFYQHkFPEVEDV K12-ub
eIF2-alpha (mouse) SCRFYQHKFPEVEDV K12
eIF2-alpha (rat) SCRFYQHKFPEVEDV K12
eIF2-alpha (rabbit) SCRFYQHKFPEVEDV K11
eIF2-alpha (fruit fly) TSRFYNERYPEIEDV R11
S26
VVMVNVRSIAEMGAY
0 1
eIF2-alpha (human) VVMVNVRsIAEMGAY S26-p
eIF2-alpha (mouse) VVMVNVRSIAEMGAY S26
eIF2-alpha (rat) VVMVNVRSIAEMGAY S26
eIF2-alpha (rabbit) VVMVNVRSIAEMGAY S25
eIF2-alpha (fruit fly) VVMVNVLSIAEMGAY S25
S49
IEGMILLSELsRrrI
4 1
eIF2-alpha (human) IEGMILLsELsRRRI S49-p
eIF2-alpha (mouse) IEGMILLSELsRrrI S49
eIF2-alpha (rat) IEGMILLSELsRRRI S49
eIF2-alpha (rabbit) IEGRILLsELsR___ S48-p
eIF2-alpha (fruit fly) IEGMILLSELSRRRI S48
S52-p
MILLSELsRrrIRSI
Upstream
Downstream
86 2
eIF2-alpha (human)
S52-p
eIF2-alpha (mouse)
S52-p
eIF2-alpha (rat)
S52-p
eIF2-alpha (rabbit)
S51-p
eIF2-alpha (fruit fly)
S51-p
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, altered
  • transcription, induced
  • translation, altered
  • translation, induced
  • translation, inhibited
Kinase, in vitro:
  • PKR (mouse)
Putative in vivo kinases:
  • GCN2 (mouse)
  • PERK (mouse)
  • PKR (mouse)
Putative upstream phosphatases:
  • PPP1CA (human)
  • PPP1CA (mouse)
  • PPP1R15B (mouse)
Regulatory protein:
  • Akt1 (mouse)
  • Akt2 (mouse)
  • Akt3 (mouse)
  • ATF-4 (mouse)
  • DDIT3 (mouse)
  • DUSP1 (mouse)
  • GADD34 (human)
  • GCN2 (mouse)
  • IRE1 (mouse)
  • NCK1 (human)
  • NCK1 (mouse)
  • NCK2 (mouse)
  • PERK (mouse)
  • PKR (mouse)
  • PPP1R15B (mouse)
  • XIAP (mouse)
Treatment
  • 2-AP
  • 2-deoxyglucose
  • adriamycin
  • Akt_inhibitor_VIII
  • amino_acid_starvation
  • arsenite
  • cycloheximide
  • diamide
  • disulfiram
  • double-stranded_RNA
  • DTT
  • exercise
  • fasting
  • Freund's_complete_adjuvant
  • glucagon
  • glucose
  • H-89
  • H2O2
  • heparin sodium
  • histidinol
  • hypoxia
  • IFN-alpha
  • IFN-gamma
  • LY294002
  • mannose
  • obesity-inducing diet
  • okadaic_acid
  • poly(I-C)
  • rapamycin
  • Sal003
  • serum_withdrawal
  • siRNA
  • SP600125
  • thapsigargin
  • TNF
  • tunicamycin
  • UV
  • virus infection
eIF2-alpha (human) MILLsELsRRRIRsI S52-p
eIF2-alpha (mouse) MILLSELsRrrIRSI S52-p
eIF2-alpha (rat) MILLSELsRRRIRSI S52-p
eIF2-alpha (rabbit) RILLsELsR______ S51-p
eIF2-alpha (fruit fly) MILLSELSRRRIRSI S51
R54-m1
LLSELsRrrIRSINK
0 2
eIF2-alpha (human) LLsELsRRRIRsINk R54
eIF2-alpha (mouse) LLSELsRrrIRSINK R54-m1
eIF2-alpha (rat) LLSELsRRRIRSINK R54
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) LLSELSRRRIRSINK R53
R55-m1
LSELsRrrIRSINKL
0 2
eIF2-alpha (human) LsELsRRRIRsINkL R55
eIF2-alpha (mouse) LSELsRrrIRSINKL R55-m1
eIF2-alpha (rat) LSELsRRRIRSINKL R55
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) LSELSRRRIRSINKL R54
S58
LsRrrIRSINKLIRI
0 1
eIF2-alpha (human) LsRRRIRsINkLIRI S58-p
eIF2-alpha (mouse) LsRrrIRSINKLIRI S58
eIF2-alpha (rat) LsRRRIRSINKLIRI S58
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) LSRRRIRSINKLIRV S57
K61
rrIRSINKLIRIGRN
0 4
eIF2-alpha (human) RRIRsINkLIRIGRN K61-ub
eIF2-alpha (mouse) rrIRSINKLIRIGRN K61
eIF2-alpha (rat) RRIRSINKLIRIGRN K61
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) RRIRSINKLIRVGKT K60
K80
VIRVDKEKGyIDLSK
0 3
eIF2-alpha (human) VIRVDKEkGyIDLsk K80-ub
eIF2-alpha (mouse) VIRVDKEKGyIDLSK K80
eIF2-alpha (rat) VIRVDKEKGYIDLSK K80
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) VIRVDKEKGYIDLSK K79
Y82-p
RVDKEKGyIDLSKRR
0 68
eIF2-alpha (human) RVDKEkGyIDLskRR Y82-p
eIF2-alpha (mouse) RVDKEKGyIDLSKRR Y82-p
eIF2-alpha (rat) RVDKEKGYIDLSKRR Y82
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) RVDKEKGYIDLSKRR Y81
S86
EKGyIDLSKRRVSPE
0 1
eIF2-alpha (human) EkGyIDLskRRVsPE S86-p
eIF2-alpha (mouse) EKGyIDLSKRRVSPE S86
eIF2-alpha (rat) EKGYIDLSKRRVSPE S86
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) EKGYIDLSKRRVSPE S85
K87
KGyIDLSKRRVSPEE
0 3
eIF2-alpha (human) kGyIDLskRRVsPEE K87-ub
eIF2-alpha (mouse) KGyIDLSKRRVSPEE K87
eIF2-alpha (rat) KGYIDLSKRRVSPEE K87
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) KGYIDLSKRRVSPED K86
S91
DLSKRRVSPEEAIKC
0 1
eIF2-alpha (human) DLskRRVsPEEAIkC S91-p
eIF2-alpha (mouse) DLSKRRVSPEEAIKC S91
eIF2-alpha (rat) DLSKRRVSPEEAIKC S91
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) DLSKRRVSPEDVEKC S90
K97
VSPEEAIKCEDkFTk
0 3
eIF2-alpha (human) VsPEEAIkCEDkFTk K97-ub
eIF2-alpha (mouse) VSPEEAIKCEDkFTk K97
eIF2-alpha (rat) VSPEEAIKCEDKFTK K97
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) VSPEDVEKCTERFAK K96
K101
EAIKCEDKFTkSkTV
0 3
eIF2-alpha (human) EAIkCEDkFTkSkTV K101-ac
eIF2-alpha (mouse) EAIKCEDKFTkSkTV K101
eIF2-alpha (rat) EAIKCEDKFTKSKTV K101
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) DVEKCTERFAKAKAI R100
K101-ub
EAIKCEDkFTkSkTV
0 5
eIF2-alpha (human) EAIkCEDkFTkSkTV K101-ub
eIF2-alpha (mouse) EAIKCEDkFTkSkTV K101-ub
eIF2-alpha (rat) EAIKCEDKFTKSKTV K101
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) DVEKCTERFAKAKAI R100
K104-ub
KCEDkFTkSkTVYsI
0 7
eIF2-alpha (human) kCEDkFTkSkTVYsI K104-ub
eIF2-alpha (mouse) KCEDkFTkSkTVYsI K104-ub
eIF2-alpha (rat) KCEDKFTKSKTVYSI K104
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) KCTERFAKAKAINSL K103
K106-ub
EDkFTkSkTVYsILR
0 5
eIF2-alpha (human) EDkFTkSkTVYsILR K106-ub
eIF2-alpha (mouse) EDkFTkSkTVYsILR K106-ub
eIF2-alpha (rat) EDKFTKSKTVYSILR K106
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TERFAKAKAINSLLR K105
S110-p
TkSkTVYsILRHVAE
0 3
eIF2-alpha (human) TkSkTVYsILRHVAE S110-p
eIF2-alpha (mouse) TkSkTVYsILRHVAE S110-p
eIF2-alpha (rat) TKSKTVYSILRHVAE S110
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) AKAKAINSLLRHVAD S109
K123
AEVLEYTKDEQLESL
0 4
eIF2-alpha (human) AEVLEYTkDEQLESL K123-ub
eIF2-alpha (mouse) AEVLEYTKDEQLESL K123
eIF2-alpha (rat) AEVLEYTKDEQLESL K123
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) ADILGFEGNEKLEDL G122
K123-ac
AEVLEYTkDEQLESL
0 1
eIF2-alpha (human) AEVLEYTKDEQLESL K123
eIF2-alpha (mouse) AEVLEYTkDEQLESL K123-ac
eIF2-alpha (rat) AEVLEYTKDEQLESL K123
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) ADILGFEGNEKLEDL G122
R133
QLESLFQRTAWVFDD
0 1
eIF2-alpha (human) QLESLFQrTAWVFDD R133-m1
eIF2-alpha (mouse) QLESLFQRTAWVFDD R133
eIF2-alpha (rat) QLESLFQRTAWVFDD R133
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) KLEDLYQKTAWHFEK K132
K141-ac
TAWVFDDkYKRPGyG
1 5
eIF2-alpha (human) TAWVFDDkYkRPGyG K141-ac
eIF2-alpha (mouse) TAWVFDDkYKRPGyG K141-ac
eIF2-alpha (rat) TAWVFDDkYKRPGYG K141-ac
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TAWHFEKKYNNKTVA K140
K141-ub
TAWVFDDkYKRPGyG
0 5
eIF2-alpha (human) TAWVFDDkYkRPGyG K141-ub
eIF2-alpha (mouse) TAWVFDDkYKRPGyG K141-ub
eIF2-alpha (rat) TAWVFDDKYKRPGYG K141
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TAWHFEKKYNNKTVA K140
K143
WVFDDkYKRPGyGAy
0 8
eIF2-alpha (human) WVFDDkYkRPGyGAy K143-ub
eIF2-alpha (mouse) WVFDDkYKRPGyGAy K143
eIF2-alpha (rat) WVFDDkYKRPGYGAY K143
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) WHFEKKYNNKTVAYD N142
K143
WVFDDkYKRPGyGAy
1 1
eIF2-alpha (human) WVFDDkYkRPGyGAy K143-ac
eIF2-alpha (mouse) WVFDDkYKRPGyGAy K143
eIF2-alpha (rat) WVFDDkYKRPGYGAY K143
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) WHFEKKYNNKTVAYD N142
Y147-p
DkYKRPGyGAyDAFK
0 14
eIF2-alpha (human) DkYkRPGyGAyDAFk Y147-p
eIF2-alpha (mouse) DkYKRPGyGAyDAFK Y147-p
eIF2-alpha (rat) DkYKRPGYGAYDAFK Y147
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) KKYNNKTVAYDIFKQ V146
Y150-p
KRPGyGAyDAFKHAV
0 88
eIF2-alpha (human) kRPGyGAyDAFkHAV Y150-p
eIF2-alpha (mouse) KRPGyGAyDAFKHAV Y150-p
eIF2-alpha (rat) KRPGYGAYDAFKHAV Y150
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) YNNKTVAYDIFKQSV Y148
K154
yGAyDAFKHAVsDPS
0 2
eIF2-alpha (human) yGAyDAFkHAVsDPS K154-ub
eIF2-alpha (mouse) yGAyDAFKHAVsDPS K154
eIF2-alpha (rat) YGAYDAFKHAVSDPS K154
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TVAYDIFKQSVTDPT K152
K154
yGAyDAFKHAVsDPS
0 2
eIF2-alpha (human) yGAyDAFkHAVsDPS K154-ac
eIF2-alpha (mouse) yGAyDAFKHAVsDPS K154
eIF2-alpha (rat) YGAYDAFKHAVSDPS K154
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TVAYDIFKQSVTDPT K152
K154
yGAyDAFKHAVsDPS
0 1
eIF2-alpha (human) yGAyDAFkHAVsDPS K154-m1
eIF2-alpha (mouse) yGAyDAFKHAVsDPS K154
eIF2-alpha (rat) YGAYDAFKHAVSDPS K154
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TVAYDIFKQSVTDPT K152
S158-p
DAFKHAVsDPSILDs
0 6
eIF2-alpha (human) DAFkHAVsDPSILDS S158-p
eIF2-alpha (mouse) DAFKHAVsDPSILDs S158-p
eIF2-alpha (rat) DAFKHAVSDPSILDS S158
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) DIFKQSVTDPTVFDE T156
S165-p
sDPSILDsLDLNEDE
0 1
eIF2-alpha (human) sDPSILDSLDLNEDE S165
eIF2-alpha (mouse) sDPSILDsLDLNEDE S165-p
eIF2-alpha (rat) SDPSILDSLDLNEDE S165
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TDPTVFDECNLEPET E163
T185-p
NNINRRLtPQAVKIR
0 5
eIF2-alpha (human) NNINRRLtPQAVkIR T185-p
eIF2-alpha (mouse) NNINRRLtPQAVKIR T185-p
eIF2-alpha (rat) NNINRRLTPQAVKIR T185
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) SNIKRKLVSPTVKIR V183
K190
RLtPQAVKIRADIEV
0 5
eIF2-alpha (human) RLtPQAVkIRADIEV K190-ub
eIF2-alpha (mouse) RLtPQAVKIRADIEV K190
eIF2-alpha (rat) RLTPQAVKIRADIEV K190
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) KLVSPTVKIRADIEC K188
Y200
ADIEVACYGYEGIDA
0 3
eIF2-alpha (human) ADIEVACyGyEGIDA Y200-p
eIF2-alpha (mouse) ADIEVACYGYEGIDA Y200
eIF2-alpha (rat) ADIEVACYGYEGIDA Y200
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) ADIECSCYGYEGIDA Y198
Y202
IEVACYGYEGIDAVK
0 14
eIF2-alpha (human) IEVACyGyEGIDAVk Y202-p
eIF2-alpha (mouse) IEVACYGYEGIDAVK Y202
eIF2-alpha (rat) IEVACYGYEGIDAVK Y202
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) IECSCYGYEGIDAVK Y200
K209
YEGIDAVKEALRAGL
0 1
eIF2-alpha (human) yEGIDAVkEALRAGL K209-ub
eIF2-alpha (mouse) YEGIDAVKEALRAGL K209
eIF2-alpha (rat) YEGIDAVKEALRAGL K209
eIF2-alpha (rabbit) under review -
eIF2-alpha (fruit fly) YEGIDAVKASLTKGL K207
S219
LRAGLNCSTETMPIK
0 1
eIF2-alpha (human) LRAGLNCsTENMPIk S219-p
eIF2-alpha (mouse) LRAGLNCSTETMPIK S219
eIF2-alpha (rat) LRAGLNCSTETMPIK S219
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) LTKGLELSTEELPIR S217
K226
STETMPIKINLIAPP
0 4
eIF2-alpha (human) sTENMPIkINLIAPP K226-ub
eIF2-alpha (mouse) STETMPIKINLIAPP K226
eIF2-alpha (rat) STETMPIKINLIAPP K226
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) STEELPIRINLIAPP R224
Y235
NLIAPPRYVMTTTTL
0 1
eIF2-alpha (human) NLIAPPRyVMTTTTL Y235-p
eIF2-alpha (mouse) NLIAPPRYVMTTTTL Y235
eIF2-alpha (rat) NLIAPPRYVMTTTTL Y235
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) NLIAPPLYVMTTSTT Y233
T245
TTTTLERTEGLSVLN
0 1
eIF2-alpha (human) TTTTLERtEGLSVLS T245-p
eIF2-alpha (mouse) TTTTLERTEGLSVLN T245
eIF2-alpha (rat) TTTTLERTEGLSVLN T245
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) TTSTTKKTDGLKALE T243
K259-ub
NQAMAVIkEKIEEKR
0 3
eIF2-alpha (human) SQAMAVIkEKIEEkr K259-ub
eIF2-alpha (mouse) NQAMAVIkEKIEEKR K259-ub
eIF2-alpha (rat) NQAMAVIKEKIEEKR K259
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) EVAIEHIRAKTSEYD R257
K265
IkEKIEEKRGVFNVQ
0 1
eIF2-alpha (human) IkEKIEEkrGVFNVQ K265-ub
eIF2-alpha (mouse) IkEKIEEKRGVFNVQ K265
eIF2-alpha (rat) IKEKIEEKRGVFNVQ K265
eIF2-alpha (rabbit) under review -
eIF2-alpha (fruit fly) under review -
R266
kEKIEEKRGVFNVQM
0 1
eIF2-alpha (human) kEKIEEkrGVFNVQM R266-m1
eIF2-alpha (mouse) kEKIEEKRGVFNVQM R266
eIF2-alpha (rat) KEKIEEKRGVFNVQM R266
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) RAKTSEYDGEFKVIM D264
K276
FNVQMEPKVVtDTDE
0 3
eIF2-alpha (human) FNVQMEPkVVtDtDE K276-ub
eIF2-alpha (mouse) FNVQMEPKVVtDTDE K276
eIF2-alpha (rat) FNVQMEPKVVTDTDE K276
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) FKVIMAPKLVTAIDE K274
T279-p
QMEPKVVtDTDETEL
0 27
eIF2-alpha (human) QMEPkVVtDtDEtEL T279-p
eIF2-alpha (mouse) QMEPKVVtDTDETEL T279-p
eIF2-alpha (rat) QMEPKVVTDTDETEL T279
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) IMAPKLVTAIDEADL T277
T281
EPKVVtDTDETELAR
0 3
eIF2-alpha (human) EPkVVtDtDEtELAR T281-p
eIF2-alpha (mouse) EPKVVtDTDETELAR T281
eIF2-alpha (rat) EPKVVTDTDETELAR T281
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) APKLVTAIDEADLAR I279
T284
VVtDTDETELARQLE
0 1
eIF2-alpha (human) VVtDtDEtELARQME T284-p
eIF2-alpha (mouse) VVtDTDETELARQLE T284
eIF2-alpha (rat) VVTDTDETELARQLE T284
eIF2-alpha (rabbit) gap -
eIF2-alpha (fruit fly) LVTAIDEADLARRLE A282
K312
DAEEMEAKAED____
0 1
eIF2-alpha (human) DAEEMEAkAED____ K312-ub
eIF2-alpha (mouse) DAEEMEAKAED____ K312
eIF2-alpha (rat) DAEEMEAKAED____ K312
eIF2-alpha (rabbit) under review -
eIF2-alpha (fruit fly) under review -