Other Species / Isoforms
  IRAK4 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K3-ac
_____MNkPItPsTY
0 1
IRAK4 (human) _____MNkPItPsTY K3-ac
IRAK4 (mouse) _____MNKPLTPSTY K3
IRAK4 (rat) _____MSKPLTPSTY K3
K3-ub
_____MNkPItPsTY
0 1
IRAK4 (human) _____MNkPItPsTY K3-ub
IRAK4 (mouse) _____MNKPLTPSTY K3
IRAK4 (rat) _____MSKPLTPSTY K3
T6-p
__MNkPItPsTYVRC
Upstream
1 1
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) __MNkPItPsTYVRC T6-p
IRAK4 (mouse) __MNKPLTPSTYIRN T6
IRAK4 (rat) __MSKPLTPSTYVRS T6
S8-p
MNkPItPsTYVRCLN
Upstream
Downstream
2 2
Effects on Modified Protein
  • molecular association, regulation
  • protein conformation
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) MNkPItPsTYVRCLN S8-p
IRAK4 (mouse) MNKPLTPSTYIRNLN S8
IRAK4 (rat) MSKPLTPSTYVRSLN S8
K33-ub
IDPQEGWkkLAVAIK
0 1
IRAK4 (human) IDPQEGWkkLAVAIK K33-ub
IRAK4 (mouse) IDPQEGWKKLAVAIK K33
IRAK4 (rat) IDPQEGWKKLAVAIK K33
K34-ac
DPQEGWkkLAVAIKK
0 2
IRAK4 (human) DPQEGWkkLAVAIKK K34-ac
IRAK4 (mouse) DPQEGWKKLAVAIKK K34
IRAK4 (rat) DPQEGWKKLAVAIKK K34
S114-p
KTANTLPskEAITVQ
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) KTANTLPskEAITVQ S114-p
IRAK4 (mouse) QTVKSLPPREAATVA P114
IRAK4 (rat) QAVHSLPPREAATVA P114
K115-ub
TANTLPskEAITVQQ
0 2
IRAK4 (human) TANTLPskEAITVQQ K115-ub
IRAK4 (mouse) TVKSLPPREAATVAQ R115
IRAK4 (rat) AVHSLPPREAATVAQ R115
S150-p
QSYMPPDsssPENKs
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) QSYMPPDsssPENKs S150-p
IRAK4 (mouse) HSCEPPDSSsPDNRS S150
IRAK4 (rat) PSCELPDSSSPGHQS S152
S151-p
SYMPPDsssPENKsL
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) SYMPPDsssPENKsL S151-p
IRAK4 (mouse) SCEPPDSSsPDNRSV S151
IRAK4 (rat) SCELPDSSSPGHQSV S153
S152-p
YMPPDsssPENKsLE
Upstream
1 5
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) YMPPDsssPENKsLE S152-p
IRAK4 (mouse) CEPPDSSsPDNRSVE S152-p
IRAK4 (rat) CELPDSSSPGHQSVE S154
S157-p
sssPENKsLEVSDTR
0 3
IRAK4 (human) sssPENKsLEVSDTR S157-p
IRAK4 (mouse) SSsPDNRSVESSDTR S157
IRAK4 (rat) SSSPGHQSVEFSDTR S159
T208-p
YKGYVNNttVAVKKL
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) YKGYVNNttVAVKKL T208-p
IRAK4 (mouse) YKGCVNNTIVAVKKL T208
IRAK4 (rat) YKGCVNNTTVAVKKL T210
T209-p
KGYVNNttVAVKKLA
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) KGYVNNttVAVKKLA T209-p
IRAK4 (mouse) KGCVNNTIVAVKKLG I209
IRAK4 (rat) KGCVNNTTVAVKKLG T211
K313-ub
HHIHRDIkSANILLD
0 2
IRAK4 (human) HHIHRDIkSANILLD K313-ub
IRAK4 (mouse) HHIHRDIKSANILLD K313
IRAK4 (rat) HHIHRDIKSANILLD K315
S336-p
DFGLARAsEkFAQtV
0 1
IRAK4 (human) DFGLARAsEkFAQtV S336-p
IRAK4 (mouse) DFGLARASARLAQtV S336
IRAK4 (rat) DFGLARASAKLAQTV S338
K338-ub
GLARAsEkFAQtVMt
0 1
IRAK4 (human) GLARAsEkFAQtVMt K338-ub
IRAK4 (mouse) GLARASARLAQtVMt R338
IRAK4 (rat) GLARASAKLAQTVMT K340
T342-p
AsEkFAQtVMtsRIV
Upstream
Downstream
3 3
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • IRAK4 (human)
Putative in vivo kinases:
  • IRAK4 (human)
IRAK4 (human) AsEkFAQtVMtsRIV T342-p
IRAK4 (mouse) ASARLAQtVMtsRIV T342-p
IRAK4 (rat) ASAKLAQTVMTSRIV T344
T345-p
kFAQtVMtsRIVGTt
Upstream
Downstream
5 4
IRAK4 (human)
T345-p
IRAK4 (mouse)
T345-p
IRAK4 (rat)
T347-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein conformation
Kinase, in vitro:
  • IRAK4 (human)
Putative in vivo kinases:
  • IRAK4 (human)
Treatment
  • compound_1
  • IL-1b
IRAK4 (human) kFAQtVMtsRIVGTt T345-p
IRAK4 (mouse) RLAQtVMtsRIVGTT T345-p
IRAK4 (rat) KLAQTVMTSRIVGTT T347
S346-p
FAQtVMtsRIVGTtA
Upstream
Downstream
3 4
IRAK4 (human)
S346-p
IRAK4 (mouse)
S346-p
IRAK4 (rat)
S348-p
Effects on Modified Protein
  • enzymatic activity, induced
  • protein conformation
Kinase, in vitro:
  • IRAK4 (human)
Putative in vivo kinases:
  • IRAK4 (human)
Treatment
  • compound_1
  • IL-1b
IRAK4 (human) FAQtVMtsRIVGTtA S346-p
IRAK4 (mouse) LAQtVMtsRIVGTTA S346-p
IRAK4 (rat) LAQTVMTSRIVGTTA S348
T352-p
tsRIVGTtAYMAPEA
Upstream
1 0
Kinase, in vitro:
  • IRAK4 (human)
IRAK4 (human) tsRIVGTtAYMAPEA T352-p
IRAK4 (mouse) tsRIVGTTAYMAPEA T352
IRAK4 (rat) TSRIVGTTAYMAPEA T354
K400-sm
PQLLLDIkEEIEDEE
0 1
IRAK4 (human) PQLLLDIkEEIEDEE K400-sm
IRAK4 (mouse) PQLLLDIKEEIEDEE K400
IRAK4 (rat) PQLLLDIKEEIEDKE K402
K416-ub
TIEDYIDkKMNDADS
0 1
IRAK4 (human) TIEDYIDkKMNDADS K416-ub
IRAK4 (mouse) TIEDYTDEKMSDADP E416
IRAK4 (rat) TIEDCTDEKMSDADP E418