Other Species / Isoforms
  RIPK1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
1 1
RIPK1 (human) ssRsNsAtEQPGSLH T337
RIPK1 iso2 (human) SSRSNSATEQPGSLH T291
RIPK1 (mouse) gap -
RIPK1 (rat) gap -
S6
__MQPDMSLDNIKMA
0 2
RIPK1 (human) __MQPDMsLNVIKMK S6
RIPK1 iso2 (human) __MQPDMSLNVIKMK S6
RIPK1 (mouse) __MQPDMSLDNIKMA S6
RIPK1 (rat) __MQPDMSLDNIKMA S6
S14
LDNIKMAssDLLEKT
Upstream
2 1
RIPK1 (human)
S14
RIPK1 iso2 (human)
S14
Treatment
  • 7N-1
  • cuprizone
RIPK1 (human) LNVIKMKssDFLEsA S14
RIPK1 iso2 (human) LNVIKMKSSDFLESA S14
RIPK1 (mouse) LDNIKMAssDLLEKT S14
RIPK1 (rat) LDNIKMASDDLLERK S14
S15
DNIKMAssDLLEKTD
Upstream
1 1
Treatment
  • 7N-1
  • cuprizone
RIPK1 (human) NVIKMKssDFLEsAE S15
RIPK1 iso2 (human) NVIKMKSSDFLESAE S15
RIPK1 (mouse) DNIKMAssDLLEKTD S15
RIPK1 (rat) DNIKMASDDLLERKD D15
K20
AssDLLEKTDLDsGG
0 1
RIPK1 (human) KssDFLEsAELDsGG S20
RIPK1 iso2 (human) KSSDFLESAELDSGG S20
RIPK1 (mouse) AssDLLEKTDLDsGG K20
RIPK1 (rat) ASDDLLERKDLDSGG R20
S25
LEKTDLDsGGFGKVS
Downstream
3 4
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
RIPK1 (human) LEsAELDsGGFGKVs S25
RIPK1 iso2 (human) LESAELDSGGFGKVS S25
RIPK1 (mouse) LEKTDLDsGGFGKVS S25
RIPK1 (rat) LERKDLDSGGFGKVS S25
S32
sGGFGKVSLCYHRSH
0 1
RIPK1 (human) sGGFGKVsLCFHRtQ S32
RIPK1 iso2 (human) SGGFGKVSLCFHRTQ S32
RIPK1 (mouse) sGGFGKVSLCYHRSH S32
RIPK1 (rat) SGGFGKVSLCFHRTH S32
S38
VSLCYHRSHGFVILK
0 2
RIPK1 (human) VsLCFHRtQGLMIMK T38
RIPK1 iso2 (human) VSLCFHRTQGLMIMK T38
RIPK1 (mouse) VSLCYHRSHGFVILK S38
RIPK1 (rat) VSLCFHRTHGFVILK T38
S161
IADLGVAsFKTWsKL
4 1
RIPK1 (human) IADLGLAsFKMWsKL S161
RIPK1 iso2 (human) IADLGLASFKMWSKL S115
RIPK1 (mouse) IADLGVAsFKTWsKL S161
RIPK1 (rat) IADLGVAsFKTWsKL S161
S166
VAsFKTWsKLtKEKD
Upstream
Downstream
41 2
RIPK1 (human)
S166
RIPK1 (mouse)
S166
RIPK1 (rat)
S166
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, induced
  • autophagy, inhibited
  • carcinogenesis, inhibited
  • signaling pathway regulation
  • transcription, induced
Putative in vivo kinases:
  • RIPK1 (human)
  • RIPK1 (mouse)
Regulatory protein:
  • APP (mouse)
  • ASIC1 (human)
  • CASP8 (human)
  • cIAP1 (human)
  • DAPK1 (human)
  • DAPK1 (mouse)
  • FADD (human)
  • MAPKAPK2 (mouse)
  • MYD88 (human)
  • MYD88 (mouse)
  • PSEN1 (mouse)
  • RIPK1 (human)
  • RIPK1 (mouse)
  • RIPK3 (human)
  • RIPK3 (mouse)
  • SPATA2 (mouse)
  • TAB2 (human)
  • TICAM1 (human)
  • TICAM1 (mouse)
  • TNIP1 (mouse)
  • TTP (mouse)
view more >
Treatment
  • 4-HT
  • adriamycin
  • AT-406
  • BV6
  • circRNA
  • cycloheximide
  • EP4-D
  • etoposide
  • high-fat diet
  • IDN-6556
  • isoproterenol
  • LDL_oxidized
  • LPS
  • LY2228820
  • MCAO/R
  • methionine- and choline-deficient diet
  • mitoxantrone
  • Necrostatin-1
  • palmitate
  • PGE2
  • phenhydan
  • poly(I-C)
  • primidone
  • Psalmotoxin
  • SM-164
  • smac
  • streptozotocin
  • TNF
  • Z-VAD-FMK
view more >
RIPK1 (human) LAsFKMWsKLNNEEH S166
RIPK1 iso2 (human) LASFKMWSKLNNEEH S120
RIPK1 (mouse) VAsFKTWsKLtKEKD S166
RIPK1 (rat) VAsFKTWsKLTKEEH S166
T169
FKTWsKLtKEKDNKQ
Upstream
2 0
Regulatory protein:
  • RIPK1 (mouse)
  • RIPK3 (mouse)
Treatment
  • 4-HT
  • BV6
  • IDN-6556
  • LPS
  • poly(I-C)
  • TNF
  • Z-VAD-FMK
view more >
RIPK1 (human) FKMWsKLNNEEHNEL N169
RIPK1 iso2 (human) FKMWSKLNNEEHNEL N123
RIPK1 (mouse) FKTWsKLtKEKDNKQ T169
RIPK1 (rat) FKTWsKLTKEEHNKQ T169
T235
PYENVICtEQFVICI
Upstream
1 1
Treatment
  • LPS
  • TNF
  • Z-VAD-FMK
view more >
RIPK1 (human) PYENAICEQQLIMCI E234
RIPK1 iso2 (human) PYENAICEQQLIMCI E188
RIPK1 (mouse) PYENVICtEQFVICI T235
RIPK1 (rat) PYENVICTEQFLVCI T234
S263
YCPREIISLMERCWQ
1 1
RIPK1 (human) YCPREIIsLMKLCWE S262
RIPK1 iso2 (human) YCPREIISLMKLCWE S216
RIPK1 (mouse) YCPREIISLMERCWQ S263
RIPK1 (rat) FCPREIISLMERCWQ S262
S292
EFRPFYLSHFEEYVE
1 1
RIPK1 (human) KFRPFYLsQLEEsVE S291
RIPK1 iso2 (human) KFRPFYLSQLEESVE S245
RIPK1 (mouse) EFRPFYLSHFEEYVE S292
RIPK1 (rat) EFKPFYLSQFEEYVE S291
Y297
YLSHFEEYVEEDVAS
1 2
RIPK1 (human) YLsQLEEsVEEDVKs S296
RIPK1 iso2 (human) YLSQLEESVEEDVKS S250
RIPK1 (mouse) YLSHFEEYVEEDVAS Y297
RIPK1 (rat) YLSQFEEYVEEDVAS Y296
S304
YVEEDVASLKKEyPD
0 2
RIPK1 (human) sVEEDVKsLKKEYsN S303
RIPK1 iso2 (human) SVEEDVKSLKKEYSN S257
RIPK1 (mouse) YVEEDVASLKKEyPD S304
RIPK1 (rat) YVEEDVASLKKEYPS S303
Y309
VASLKKEyPDQsPVL
0 1
RIPK1 (human) VKsLKKEYsNENAVV Y308
RIPK1 iso2 (human) VKSLKKEYSNENAVV Y262
RIPK1 (mouse) VASLKKEyPDQsPVL Y309
RIPK1 (rat) VASLKKEYPSQsPVL Y308
P310
ASLKKEyPDQsPVLQ
0 1
RIPK1 (human) KsLKKEYsNENAVVK S309
RIPK1 iso2 (human) KSLKKEYSNENAVVK S263
RIPK1 (mouse) ASLKKEyPDQsPVLQ P310
RIPK1 (rat) ASLKKEYPSQsPVLK P309
S313
KKEyPDQsPVLQRMF
Upstream
1 30
Regulatory protein:
  • KRas (mouse)
Treatment
  • LPS
  • TNF
  • Z-VAD-FMK
view more >
RIPK1 (human) KKEYsNENAVVKRMQ N312
RIPK1 iso2 (human) KKEYSNENAVVKRMQ N266
RIPK1 (mouse) KKEyPDQsPVLQRMF S313
RIPK1 (rat) KKEYPSQsPVLKRMF S312
S321
PVLQRMFsLQHDCVP
Upstream
Downstream
12 61
RIPK1 (human)
S320
RIPK1 iso2 (human)
S274
RIPK1 (mouse)
S321
Effects on Modified Protein
  • enzymatic activity, induced
  • enzymatic activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • MAPKAPK2 (human)
  • MAPKAPK2 (mouse)
  • TAK1 (human)
view more >
Putative in vivo kinases:
  • MAPKAPK2 (human)
  • MAPKAPK2 (mouse)
  • TAK1 (human)
  • TAK1 (mouse)
view more >
Regulatory protein:
  • DAPK1 (mouse)
  • PARK2 (human)
  • TAB2 (human)
view more >
Treatment
  • (5Z)-7-oxozeaenol
  • bacterial infection
  • IL-33
  • insulin
  • isoproterenol
  • PF3644022
  • SB203580
  • SM-164
  • TAK1_inhibitor
  • TNF
view more >
RIPK1 (human) AVVKRMQsLQLDCVA S320
RIPK1 iso2 (human) AVVKRMQSLQLDCVA S274
RIPK1 (mouse) PVLQRMFsLQHDCVP S321
RIPK1 (rat) PVLKRMFsLQHDCVP S320
P331
HDCVPLPPsRsNsEQ
0 4
RIPK1 (human) LDCVAVPssRsNsAt S330
RIPK1 iso2 (human) LDCVAVPSSRSNSAT S284
RIPK1 (mouse) HDCVPLPPsRsNsEQ P331
RIPK1 (rat) HDCVPLPPSRSNSEQ P330
S332
DCVPLPPsRsNsEQP
Upstream
Downstream
1 5
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Putative in vivo kinases:
  • TAK1 (mouse)
Treatment
  • TNF
RIPK1 (human) DCVAVPssRsNsAtE S331
RIPK1 iso2 (human) DCVAVPSSRSNSATE S285
RIPK1 (mouse) DCVPLPPsRsNsEQP S332
RIPK1 (rat) DCVPLPPSRSNSEQP S331
S334
VPLPPsRsNsEQPGS
Upstream
Downstream
2 3
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Putative in vivo kinases:
  • TAK1 (mouse)
Treatment
  • TNF
RIPK1 (human) VAVPssRsNsAtEQP S333
RIPK1 iso2 (human) VAVPSSRSNSATEQP S287
RIPK1 (mouse) VPLPPsRsNsEQPGS S334
RIPK1 (rat) VPLPPSRSNSEQPGS S333
S336
LPPsRsNsEQPGSLH
Upstream
Downstream
4 2
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • MAPKAPK2 (mouse)
Putative in vivo kinases:
  • MAPKAPK2 (human)
  • MAPKAPK2 (mouse)
Treatment
  • bacterial infection
  • PF3644022
  • SB203580
  • TNF
view more >
RIPK1 (human) VPssRsNsAtEQPGS S335
RIPK1 iso2 (human) VPSSRSNSATEQPGS S289
RIPK1 (mouse) LPPsRsNsEQPGSLH S336
RIPK1 (rat) LPPSRSNSEQPGSLH S335
S344
EQPGSLHSSQGLQMG
1 1
RIPK1 (human) EQPGSLHssQGLGMG S345
RIPK1 iso2 (human) EQPGSLHSSQGLGMG S299
RIPK1 (mouse) EQPGSLHSSQGLQMG S344
RIPK1 (rat) EQPGSLHSSQGLPMG S343
S345
QPGSLHSSQGLQMGP
1 1
RIPK1 (human) QPGSLHssQGLGMGP S346
RIPK1 iso2 (human) QPGSLHSSQGLGMGP S300
RIPK1 (mouse) QPGSLHSSQGLQMGP S345
RIPK1 (rat) QPGSLHSSQGLPMGP S344
S356
QMGPVEESWFSSSPE
1 1
RIPK1 (human) GMGPVEEsWFAPSLE S357
RIPK1 iso2 (human) GMGPVEESWFAPSLE S311
RIPK1 (mouse) QMGPVEESWFSSSPE S356
RIPK1 (rat) PMGPVEESWFSSSPE S355
Y383
KLQEEASyHAFGIFA
Downstream
1 296
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, inhibited
RIPK1 (human) KLQDEANyHLyGsRM Y384
RIPK1 iso2 (human) KLQDEANYHLYGSRM Y338
RIPK1 (mouse) KLQEEASyHAFGIFA Y383
RIPK1 (rat) KLQEEASYHAFGIFA Y382
F386
EEASyHAFGIFAEKQ
1 213
RIPK1 (human) DEANyHLyGsRMDRQ Y387
RIPK1 iso2 (human) DEANYHLYGSRMDRQ Y341
RIPK1 (mouse) EEASyHAFGIFAEKQ F386
RIPK1 (rat) EEASYHAFGIFAEKQ F385
I388
ASyHAFGIFAEKQTK
1 5
RIPK1 (human) ANyHLyGsRMDRQTK S389
RIPK1 iso2 (human) ANYHLYGSRMDRQTK S343
RIPK1 (mouse) ASyHAFGIFAEKQTK I388
RIPK1 (rat) ASYHAFGIFAEKQTK I387
S415
EERKRRVsHDPFAQQ
Upstream
0 18
RIPK1 (human)
S416
RIPK1 (mouse)
S415
RIPK1 (rat)
S414
Treatment
  • IL-33
RIPK1 (human) EERRRRVsHDPFAQQ S416
RIPK1 iso2 (human) EERRRRVSHDPFAQQ S370
RIPK1 (mouse) EERKRRVsHDPFAQQ S415
RIPK1 (rat) EERKRRVsHDPFAQQ S414
R425
PFAQQRARENIKSAG
0 36
RIPK1 (human) PFAQQRPyENFQNTE Y426
RIPK1 iso2 (human) PFAQQRPYENFQNTE Y380
RIPK1 (mouse) PFAQQRARENIKSAG R425
RIPK1 (rat) PFAQQRVHENVKSAG H424
S437
SAGARGHsDPSTTSR
0 2
RIPK1 (human) NTEGKGTAYSSAASH A438
RIPK1 iso2 (human) NTEGKGTAYSSAASH A392
RIPK1 (mouse) SAGARGHsDPSTTSR S437
RIPK1 (rat) SAGAKGLPYPSTTSH P436
V459
SWPATQTVWNNGLYN
1 4
RIPK1 (human) TSQPQVLyQNNGLys Y463
RIPK1 iso2 (human) TSQPQVLYQNNGLYS Y417
RIPK1 (mouse) SWPATQTVWNNGLYN V459
RIPK1 (rat) ASQIKVPLWNNGVYN L461
Y465
TVWNNGLYNQHGFGT
1 10
RIPK1 (human) LyQNNGLyssHGFGT Y469
RIPK1 iso2 (human) LYQNNGLYSSHGFGT Y423
RIPK1 (mouse) TVWNNGLYNQHGFGT Y465
RIPK1 (rat) PLWNNGVYNHHGFGA Y467
N466
VWNNGLYNQHGFGTT
0 1
RIPK1 (human) yQNNGLyssHGFGTR S470
RIPK1 iso2 (human) YQNNGLYSSHGFGTR S424
RIPK1 (mouse) VWNNGLYNQHGFGTT N466
RIPK1 (rat) LWNNGVYNHHGFGAT N468
Q467
WNNGLYNQHGFGTTG
0 2
RIPK1 (human) QNNGLyssHGFGTRP S471
RIPK1 iso2 (human) QNNGLYSSHGFGTRP S425
RIPK1 (mouse) WNNGLYNQHGFGTTG Q467
RIPK1 (rat) WNNGVYNHHGFGATG H469
-
gap
0 1
RIPK1 (human) TRPLDPGtAGPRVWy T483
RIPK1 iso2 (human) TRPLDPGTAGPRVWY T437
RIPK1 (mouse) gap -
RIPK1 (rat) gap -
Y479
TTGTGVWYPPNLSQM
0 3
RIPK1 (human) tAGPRVWyRPIPSHM Y490
RIPK1 iso2 (human) TAGPRVWYRPIPSHM Y444
RIPK1 (mouse) TTGTGVWYPPNLSQM Y479
RIPK1 (rat) ATGTGVWYGPSVSQS Y481
S502
PETNIPGSTPTMPYF
0 1
RIPK1 (human) PETNYLGNTPTMPFS N513
RIPK1 iso2 (human) PETNYLGNTPTMPFS N467
RIPK1 (mouse) PETNIPGSTPTMPYF S502
RIPK1 (rat) PETNLPGsIPTMPYI S504
Y520
VADDLIKYTIFNSSG
1 0
RIPK1 (human) PTDESIKyTIyNSTG Y531
RIPK1 iso2 (human) PTDESIKYTIYNSTG Y485
RIPK1 (mouse) VADDLIKYTIFNSSG Y520
RIPK1 (rat) PPDDSIRCTIYNSSR C522
F523
DLIKYTIFNSSGIQI
1 0
RIPK1 (human) ESIKyTIyNSTGIQI Y534
RIPK1 iso2 (human) ESIKYTIYNSTGIQI Y488
RIPK1 (mouse) DLIKYTIFNSSGIQI F523
RIPK1 (rat) DSIRCTIYNSSRVQI Y525
S595
RKLGFTESQIDEIDH
0 1
RIPK1 (human) RKLGFTQsQIDEIDH S610
RIPK1 iso2 (human) RKLGFTQSQIDEIDH S564
RIPK1 (mouse) RKLGFTESQIDEIDH S595
RIPK1 (rat) RKLGFTESQIDEIDH S597
H649
CRIDLLNHLIRASQS
0 1
RIPK1 (human) SRIDLLSsLIYVSQN S664
RIPK1 iso2 (human) SRIDLLSSLIYVSQN S618
RIPK1 (mouse) CRIDLLNHLIRASQS H649
RIPK1 (rat) CRTDLLNQLIQASQS Q651