Other Species / Isoforms
  MCL1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
R5
___MFGLRRNAVIGL
0 1
MCL1 (human) ___MFGLkRNAVIGL K5-ub
MCL1 iso2 (human) ___MFGLKRNAVIGL K5
MCL1 (mouse) ___MFGLRRNAVIGL R5
MCL1 (rat) ___MFGLRRNAVIGL R5
R5
___MFGLRRNAVIGL
0 1
MCL1 (human) ___MFGLkRNAVIGL K5-m1
MCL1 iso2 (human) ___MFGLKRNAVIGL K5
MCL1 (mouse) ___MFGLRRNAVIGL R5
MCL1 (rat) ___MFGLRRNAVIGL R5
E36
AGARLVAEEAkARRE
1 47
MCL1 (human) GRLLATEkEASARRE K40-ub
MCL1 iso2 (human) GRLLATEKEASARRE K40
MCL1 (mouse) AGARLVAEEAkARRE E36
MCL1 (rat) AGTRLAAEEAKARRE E36
K39-ub
RLVAEEAkARREGGG
0 1
MCL1 (human) LATEkEASARREIGG S43
MCL1 iso2 (human) LATEKEASARREIGG S43
MCL1 (mouse) RLVAEEAkARREGGG K39-ub
MCL1 (rat) RLAAEEAKARREGGG K39
-
gap
7 5
MCL1 (human)
S64-p
MCL1 (human) IGGSAGAsPPStLtP S64-p
MCL1 iso2 (human) IGGSAGASPPSTLTP S64
MCL1 (mouse) gap -
MCL1 (rat) gap -
-
gap
1 1
MCL1 (human) AGAsPPStLtPDSRR T68-p
MCL1 iso2 (human) AGASPPSTLTPDSRR T68
MCL1 (mouse) gap -
MCL1 (rat) gap -
L51
GGGEAALLPGARVVA
2 0
MCL1 (human) AsPPStLtPDSRRVA T70-p
MCL1 iso2 (human) ASPPSTLTPDSRRVA T70
MCL1 (mouse) GGGEAALLPGARVVA L51
MCL1 (rat) GGGEAALLPGARVVA L51
S73
EDPDVTASAERRLHK
7 5
MCL1 (human) EVPDVTAtPARLLFF T92-p
MCL1 iso2 (human) EVPDVTATPARLLFF T92
MCL1 (mouse) EDPDVTASAERRLHK S73
MCL1 (rat) EDPDVTASAERRLLK S73
S102-p
SAAAAIVsPEEELDG
Upstream
Downstream
7 4
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • JNK3 (human)
Putative in vivo kinases:
  • JNK3 (mouse)
Treatment
  • anisomycin
  • injury
MCL1 (human) PAADAIMsPEEELDG S121-p
MCL1 iso2 (human) PAADAIMSPEEELDG S121
MCL1 (mouse) SAAAAIVsPEEELDG S102-p
MCL1 (rat) ASAAAIMSPEEELDG S101
C110
PEEELDGCEPEAIGk
0 1
MCL1 (human) PEEELDGyEPEPLGk Y129-p
MCL1 iso2 (human) PEEELDGYEPEPLGK Y129
MCL1 (mouse) PEEELDGCEPEAIGk C110
MCL1 (rat) PEEELDGCEPEVLSK C109
K117-ub
CEPEAIGkRPAVLPL
2 12
MCL1 (human) yEPEPLGkRPAVLPL K136-ub
MCL1 iso2 (human) YEPEPLGKRPAVLPL K136
MCL1 (mouse) CEPEAIGkRPAVLPL K117-ub
MCL1 (rat) CEPEVLSKRPAVLPL K116
A131
LLERVSEAAkSsGAD
0 2
MCL1 (human) LLELVGEsGNNtStD S150-p
MCL1 iso2 (human) LLELVGESGNNTSTD S150
MCL1 (mouse) LLERVSEAAkSsGAD A131
MCL1 (rat) LLERVSEAAKSSGAD A130
K133-ub
ERVSEAAkSsGADGs
0 8
MCL1 (human) ELVGEsGNNtStDGs N152
MCL1 iso2 (human) ELVGESGNNTSTDGS N152
MCL1 (mouse) ERVSEAAkSsGADGs K133-ub
MCL1 (rat) ERVSEAAKSSGADGS K132
S135-p
VSEAAkSsGADGsLP
0 3
MCL1 (human) VGEsGNNtStDGsLP T154-p
MCL1 iso2 (human) VGESGNNTSTDGSLP T154
MCL1 (mouse) VSEAAkSsGADGsLP S135-p
MCL1 (rat) VSEAAKSSGADGSLP S134
A137
EAAkSsGADGsLPSt
1 0
MCL1 (human) EsGNNtStDGsLPst T156-p
MCL1 iso2 (human) ESGNNTSTDGSLPST T156
MCL1 (mouse) EAAkSsGADGsLPSt A137
MCL1 (rat) EAAKSSGADGSLPSt A136
S140-p
kSsGADGsLPStPPP
Downstream
12 7
MCL1 (mouse)
S140-p
Effects on Modified Protein
  • protein degradation
MCL1 (human) NNtStDGsLPstPPP S159-p
MCL1 iso2 (human) NNTSTDGSLPSTPPP S159
MCL1 (mouse) kSsGADGsLPStPPP S140-p
MCL1 (rat) KSSGADGSLPStPPP S139
S143
GADGsLPStPPPPEE
1 0
MCL1 (human) StDGsLPstPPPAEE S162-p
MCL1 iso2 (human) STDGSLPSTPPPAEE S162
MCL1 (mouse) GADGsLPStPPPPEE S143
MCL1 (rat) GADGSLPStPPPPEE S142
T144-p
ADGsLPStPPPPEEE
Upstream
Downstream
15 23
MCL1 (human)
T163-p
MCL1 iso2 (human)
T163-p
MCL1 (mouse)
T144-p
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
  • JNK3 (human)
Putative in vivo kinases:
  • JNK3 (mouse)
  • mTOR (mouse)
Treatment
  • Torin1
MCL1 (human) tDGsLPstPPPAEEE T163-p
MCL1 iso2 (human) TDGSLPSTPPPAEEE T163
MCL1 (mouse) ADGsLPStPPPPEEE T144-p
MCL1 (rat) ADGSLPStPPPPEEE T143-p
K175-ub
REQATGSkDSkPLGE
3 37
MCL1 (human) REQATGAkDTkPMGR K194-ub
MCL1 iso2 (human) REQATGAKDTKPMGR K194
MCL1 (mouse) REQATGSkDSkPLGE K175-ub
MCL1 (rat) REQATGSKDAKPLGE K174
K178-ub
ATGSkDSkPLGEAGA
3 32
MCL1 (human) ATGAkDTkPMGRSGA K197-ub
MCL1 iso2 (human) ATGAKDTKPMGRSGA K197
MCL1 (mouse) ATGSkDSkPLGEAGA K178-ub
MCL1 (rat) ATGSKDAKPLGEAGA K177
K215
AFQGMLRKLDIkNEG
0 5
MCL1 (human) AFQGMLRkLDIkNED K234-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) AFQGMLRKLDIkNEG K215
MCL1 (rat) AFQGMLRKLDIKNED K214
K219-ub
MLRKLDIkNEGDVKS
0 8
MCL1 (human) MLRkLDIkNEDDVks K238-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) MLRKLDIkNEGDVKS K219-ub
MCL1 (rat) MLRKLDIKNEDDVKS K218
K225
IkNEGDVKSFSRVMV
0 15
MCL1 (human) IkNEDDVksLSRVMI K244-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) IkNEGDVKSFSRVMV K225
MCL1 (rat) IKNEDDVKSFSRVMT K224
S226
kNEGDVKSFSRVMVH
0 1
MCL1 (human) kNEDDVksLSRVMIH S245-p
MCL1 iso2 (human) gap -
MCL1 (mouse) kNEGDVKSFSRVMVH S226
MCL1 (rat) KNEDDVKSFSRVMTH S225
K257
SFGAFVAKHLkSVNQ
0 1
MCL1 (human) SFGAFVAkHLkTINQ K276-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) SFGAFVAKHLkSVNQ K257
MCL1 (rat) SFGAFVAKHLKSINQ K256
K260-ub
AFVAKHLkSVNQESF
1 5
MCL1 (human) AFVAkHLkTINQESC K279-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) AFVAKHLkSVNQESF K260-ub
MCL1 (rat) AFVAKHLKSINQESC K259
T282
ITDVLVRTKRDWLVK
1 0
MCL1 (human) ITDVLVRtkRDWLVk T301-p
MCL1 iso2 (human) gap -
MCL1 (mouse) ITDVLVRTKRDWLVK T282
MCL1 (rat) ITDVLVRTKRDWLVK T281
K283
TDVLVRTKRDWLVKQ
0 1
MCL1 (human) TDVLVRtkRDWLVkQ K302-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) TDVLVRTKRDWLVKQ K283
MCL1 (rat) TDVLVRTKRDWLVKQ K282
K289
TKRDWLVKQRGWDGF
1 10
MCL1 (human) tkRDWLVkQRGWDGF K308-ub
MCL1 iso2 (human) gap -
MCL1 (mouse) TKRDWLVKQRGWDGF K289
MCL1 (rat) TKRDWLVKQRGWDGF K288
Y328
GVGAGLAYLIR____
0 1
MCL1 (human) GVGAGLAyLIR____ Y347-p
MCL1 iso2 (human) gap -
MCL1 (mouse) GVGAGLAYLIR____ Y328
MCL1 (rat) GVGAGLAYLIR____ Y327
-
gap
0 4
MCL1 (human) gap -
MCL1 iso2 (human) SWFGISNkIALL___ K267-ub
MCL1 (mouse) gap -
MCL1 (rat) gap -