Other Species / Isoforms
  FOXO3A (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S7-p
_MAEAPAsPVPLsPL
Upstream
2 41
FOXO3A (human)
S7-p
FOXO3A (mouse)
S7-p
FOXO3A (rat)
S7-p
Treatment
  • insulin
FOXO3A (human) _MAEAPAsPAPLsPL S7-p
FOXO3A (mouse) _MAEAPAsPVPLsPL S7-p
FOXO3A (rat) _MAEAPAsPVPLsPL S7-p
S12-p
PAsPVPLsPLEVELD
Upstream
1 36
Treatment
  • insulin
FOXO3A (human) PAsPAPLsPLEVELD S12-p
FOXO3A (mouse) PAsPVPLsPLEVELD S12-p
FOXO3A (rat) PAsPVPLsPLEVELD S12-p
S26
DPEFEPQSRPRSCtW
0 1
FOXO3A (human) DPEFEPQsRPRsCtW S26-p
FOXO3A (mouse) DPEFEPQSRPRSCtW S26
FOXO3A (rat) DPEFEPQSRPRSCtW S26
S30
EPQSRPRSCtWPLQR
1 6
FOXO3A (human) EPQsRPRsCtWPLQR S30-p
FOXO3A (mouse) EPQSRPRSCtWPLQR S30
FOXO3A (rat) EPQSRPRSCtWPLQR S30
T32-p
QSRPRSCtWPLQRPE
Upstream
Downstream
61 99
FOXO3A (human)
T32-p
FOXO3A (mouse)
T32-p
FOXO3A (rat)
T32-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • cell cycle regulation
  • cell growth, altered
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, inhibited
  • translation, inhibited
Kinase, in vitro:
  • Akt1 (mouse)
Putative in vivo kinases:
  • Akt1 (human)
  • SGK1 (human)
Regulatory protein:
  • FGFR1 (human)
  • FLT3 (human)
  • GILZ (human)
  • ITGB1 (human)
  • LST8 (mouse)
  • RICTOR (mouse)
  • SHC1 (mouse)
  • Sin1 (mouse)
  • SIRT1 (mouse)
  • TMEM55B (mouse)
  • TSC1 (mouse)
  • TSC2 (mouse)
Treatment
  • angiotensin_2
  • anti-IgM
  • BDNF
  • calyculin_A
  • ciclosporin
  • colforsin
  • differentiation
  • Dynasore
  • EGF
  • Epo
  • ethanol
  • exercise
  • fasting
  • FK506
  • FL
  • glucose
  • H2O2
  • IBMX
  • IGF-1
  • IL-2
  • IL-3
  • imatinib
  • insulin
  • KU-0063794
  • LY294002
  • okadaic_acid
  • PD98059
  • PDGF
  • rapamycin
  • SCF
  • serum
  • thapsigargin
  • U0126
  • wortmannin
FOXO3A (human) QsRPRsCtWPLQRPE T32-p
FOXO3A (mouse) QSRPRSCtWPLQRPE T32-p
FOXO3A (rat) QSRPRSCtWPLQRPE T32-p
S43-p
QRPELQAsPAKPsGE
0 5
FOXO3A (human) QRPELQAsPAKPSGE S43-p
FOXO3A (mouse) QRPELQAsPAKPsGE S43-p
FOXO3A (rat) QRPELQASPAKPSGE S43
S48-p
QAsPAKPsGETAADs
0 1
FOXO3A (human) QAsPAKPSGETAADS S48
FOXO3A (mouse) QAsPAKPsGETAADs S48-p
FOXO3A (rat) QASPAKPSGETAADS S48
S55-p
sGETAADsMIPEEDD
0 1
FOXO3A (human) SGETAADSMIPEEED S55
FOXO3A (mouse) sGETAADsMIPEEDD S55-p
FOXO3A (rat) SGETAADSMIPEEDD S55
S75
DGGGRASSAMVIGGG
0 3
FOXO3A (human) DGGGRAGsAMAIGGG S75-p
FOXO3A (mouse) DGGGRASSAMVIGGG S75
FOXO3A (rat) DSGGRGSSAMVIGGG S75
S89-p
GVSSTLGsGLLLEDS
1 1
FOXO3A (human) GGSGTLGsGLLLEDS S90-p
FOXO3A (mouse) GVSSTLGsGLLLEDS S89-p
FOXO3A (rat) GVSSALGSGLLLEDS S89
S160
RNAWGNLSYADLITR
0 1
FOXO3A (human) RNAWGNLsyADLITR S161-p
FOXO3A (mouse) RNAWGNLSYADLITR S160
FOXO3A (rat) RNAWGNLSYADLITR S160
Y161
NAWGNLSYADLITRA
0 1
FOXO3A (human) NAWGNLsyADLITRA Y162-p
FOXO3A (mouse) NAWGNLSYADLITRA Y161
FOXO3A (rat) NAWGNLSYADLITRA Y161
T178
SSPDKRLTLSQIYEW
2 1
FOXO3A (human) SSPDKRLtLSQIyEW T179-p
FOXO3A (mouse) SSPDKRLTLSQIYEW T178
FOXO3A (rat) SSPDKRLTLSQIYEW T178
Y183
RLTLSQIYEWMVRCV
0 9
FOXO3A (human) RLtLSQIyEWMVRCV Y184-p
FOXO3A (mouse) RLTLSQIYEWMVRCV Y183
FOXO3A (rat) RLTLSQIYEWMVRCV Y183
S208-p
SSAGWKNsIRHNLSL
Downstream
4 0
Effects on Modified Protein
  • protein stabilization
FOXO3A (human) SSAGWKNsIRHNLsL S209-p
FOXO3A (mouse) SSAGWKNsIRHNLSL S208-p
FOXO3A (rat) SSAGWKNSIRHNLSL S208
S214
NsIRHNLSLHSRFMR
1 2
FOXO3A (human) NsIRHNLsLHSRFMR S215-p
FOXO3A (mouse) NsIRHNLSLHSRFMR S214
FOXO3A (rat) NSIRHNLSLHSRFMR S214
S230
QNEGTGKSSWWIINP
1 0
FOXO3A (human) QNEGTGKssWWIINP S231-p
FOXO3A (mouse) QNEGTGKSSWWIINP S230
FOXO3A (rat) QNEGTGKSSWWIINP S230
S231
NEGTGKSSWWIINPD
1 0
FOXO3A (human) NEGTGKssWWIINPD S232-p
FOXO3A (mouse) NEGTGKSSWWIINPD S231
FOXO3A (rat) NEGTGKSSWWIINPD S231
K241-ac
IINPDGGkSGKAPRR
5 0
FOXO3A (human) IINPDGGksGkAPRR K242-ac
FOXO3A (mouse) IINPDGGkSGKAPRR K241-ac
FOXO3A (rat) IINPDGGKSGKAPRR K241
S242
INPDGGkSGKAPRRR
1 0
FOXO3A (human) INPDGGksGkAPRRR S243-p
FOXO3A (mouse) INPDGGkSGKAPRRR S242
FOXO3A (rat) INPDGGKSGKAPRRR S242
K244
PDGGkSGKAPRRRAV
1 0
FOXO3A (human) PDGGksGkAPRRRAV K245-ac
FOXO3A (mouse) PDGGkSGKAPRRRAV K244
FOXO3A (rat) PDGGKSGKAPRRRAV K244
S252-p
APRRRAVsMDNSNkY
Upstream
Downstream
24 92
FOXO3A (human)
S253-p
FOXO3A (mouse)
S252-p
FOXO3A (rat)
S252-p
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, inhibited
  • translation, inhibited
Regulatory protein:
  • GILZ (human)
  • ITGB1 (human)
Treatment
  • exercise
  • insulin
FOXO3A (human) APRRRAVsMDNSNkY S253-p
FOXO3A (mouse) APRRRAVsMDNSNkY S252-p
FOXO3A (rat) APRRRAVsMDNSNkY S252-p
K258-ac
VsMDNSNkYTKSRGR
5 1
FOXO3A (human) VsMDNSNkYTKSRGR K259-ac
FOXO3A (mouse) VsMDNSNkYTKSRGR K258-ac
FOXO3A (rat) VsMDNSNkYTKSRGR K258-ac
K270-ac
RGRAAKKkAALQAAP
3 0
FOXO3A (human) RGRAAKKkAALQTAP K271-ac
FOXO3A (mouse) RGRAAKKkAALQAAP K270-ac
FOXO3A (rat) RGRAAKKKAALQAAP K270
S279-p
ALQAAPEsADDsPsQ
0 16
FOXO3A (human) ALQTAPEsADDsPsQ S280-p
FOXO3A (mouse) ALQAAPEsADDsPsQ S279-p
FOXO3A (rat) ALQAAPESADDsPSQ S279
S283-p
APEsADDsPsQLSkW
1 25
FOXO3A (human) APEsADDsPsQLskW S284-p
FOXO3A (mouse) APEsADDsPsQLSkW S283-p
FOXO3A (rat) APESADDsPSQLSKW S283-p
S285-p
EsADDsPsQLSkWPG
0 3
FOXO3A (human) EsADDsPsQLskWPG S286-p
FOXO3A (mouse) EsADDsPsQLSkWPG S285-p
FOXO3A (rat) ESADDsPSQLSKWPG S285
S288
DDsPsQLSkWPGsPT
0 2
FOXO3A (human) DDsPsQLskWPGsPt S289-p
FOXO3A (mouse) DDsPsQLSkWPGsPT S288
FOXO3A (rat) DDsPSQLSKWPGsPT S288
K289-ac
DsPsQLSkWPGsPTS
5 0
FOXO3A (human) DsPsQLskWPGsPts K290-ac
FOXO3A (mouse) DsPsQLSkWPGsPTS K289-ac
FOXO3A (rat) DsPSQLSKWPGsPTS K289
S293-p
QLSkWPGsPTSRssD
Upstream
Downstream
4 81
FOXO3A (human)
S294-p
FOXO3A (mouse)
S293-p
FOXO3A (rat)
S293-p
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • ERK1 (mouse)
  • ERK2 (mouse)
Treatment
  • Trametinib
FOXO3A (human) QLskWPGsPtsRsSD S294-p
FOXO3A (mouse) QLSkWPGsPTSRssD S293-p
FOXO3A (rat) QLSKWPGsPTSRSSD S293-p
T295
SkWPGsPTSRssDEL
0 2
FOXO3A (human) skWPGsPtsRsSDEL T296-p
FOXO3A (mouse) SkWPGsPTSRssDEL T295
FOXO3A (rat) SKWPGsPTSRSSDEL T295
S296
kWPGsPTSRssDELD
0 2
FOXO3A (human) kWPGsPtsRsSDELD S297-p
FOXO3A (mouse) kWPGsPTSRssDELD S296
FOXO3A (rat) KWPGsPTSRSSDELD S296
S298-p
PGsPTSRssDELDAW
Upstream
0 8
Treatment
  • insulin
FOXO3A (human) PGsPtsRsSDELDAW S299-p
FOXO3A (mouse) PGsPTSRssDELDAW S298-p
FOXO3A (rat) PGsPTSRSSDELDAW S298
S299-p
GsPTSRssDELDAWT
1 2
FOXO3A (human) GsPtsRsSDELDAWt S300
FOXO3A (mouse) GsPTSRssDELDAWT S299-p
FOXO3A (rat) GsPTSRSSDELDAWT S299
T306
sDELDAWTDFRsRTN
0 2
FOXO3A (human) SDELDAWtDFRsRTN T307-p
FOXO3A (mouse) sDELDAWTDFRsRTN T306
FOXO3A (rat) SDELDAWTDFRSRTN T306
S310-p
DAWTDFRsRTNsNAs
Upstream
0 8
Treatment
  • insulin
  • MK-2206
FOXO3A (human) DAWtDFRsRTNsNAs S311-p
FOXO3A (mouse) DAWTDFRsRTNsNAs S310-p
FOXO3A (rat) DAWTDFRSRTNSNAS S310
S314-p
DFRsRTNsNAsTVsG
Downstream
4 1
Effects on Modified Protein
  • intracellular localization
FOXO3A (human) DFRsRTNsNAstVsG S315-p
FOXO3A (mouse) DFRsRTNsNAsTVsG S314-p
FOXO3A (rat) DFRSRTNSNASTVSG S314
S317-p
sRTNsNAsTVsGRLS
Downstream
7 1
FOXO3A (human)
S318-p
FOXO3A (mouse)
S317-p
FOXO3A (rat)
S317-p
Effects on Modified Protein
  • intracellular localization
FOXO3A (human) sRTNsNAstVsGRLs S318-p
FOXO3A (mouse) sRTNsNAsTVsGRLS S317-p
FOXO3A (rat) SRTNSNASTVSGRLS S317
T318
RTNsNAsTVsGRLSP
0 1
FOXO3A (human) RTNsNAstVsGRLsP T319-p
FOXO3A (mouse) RTNsNAsTVsGRLSP T318
FOXO3A (rat) RTNSNASTVSGRLSP T318
S320-p
NsNAsTVsGRLSPIL
Downstream
7 0
FOXO3A (human)
S321-p
FOXO3A (mouse)
S320-p
FOXO3A (rat)
S320-p
Effects on Modified Protein
  • intracellular localization
FOXO3A (human) NsNAstVsGRLsPIM S321-p
FOXO3A (mouse) NsNAsTVsGRLSPIL S320-p
FOXO3A (rat) NSNASTVSGRLSPIL S320
S324
sTVsGRLSPILASTE
0 1
FOXO3A (human) stVsGRLsPIMASTE S325-p
FOXO3A (mouse) sTVsGRLSPILASTE S324
FOXO3A (rat) STVSGRLSPILASTE S324
S343
QDDDGPLSPMLYSSS
1 2
FOXO3A (human) QDDDAPLsPMLYSSS S344-p
FOXO3A (mouse) QDDDGPLSPMLYSSS S343
FOXO3A (rat) QDDDGPLSPMLYSSS S343
S354
YSSSASLSPSVSKPC
0 1
FOXO3A (human) YSSSASLsPSVSKPC S355-p
FOXO3A (mouse) YSSSASLSPSVSKPC S354
FOXO3A (rat) YSSSASLSPSVSKPC S354
A394
DDLLDNIALPPSQPS
0 1
FOXO3A (human) DDLLDNItLPPsQPs T395-p
FOXO3A (mouse) DDLLDNIALPPSQPS A394
FOXO3A (rat) DDLLDNIALPPSQAS A394
S398
DNIALPPSQPSPPGG
2 1
FOXO3A (human) DNItLPPsQPsPTGG S399-p
FOXO3A (mouse) DNIALPPSQPSPPGG S398
FOXO3A (rat) DNIALPPSQASPPGG S398
S401
ALPPSQPSPPGGLMQ
0 1
FOXO3A (human) tLPPsQPsPTGGLMQ S402-p
FOXO3A (mouse) ALPPSQPSPPGGLMQ S401
FOXO3A (rat) ALPPSQASPPGGLMQ S401
S412-p
GLMQRGSsFPYTAKs
Upstream
4 9
FOXO3A (human)
S413-p
Putative in vivo kinases:
  • AMPKA1 (human)
Treatment
  • ethanol
FOXO3A (human) GLMQRSSsFPYTTKG S413-p
FOXO3A (mouse) GLMQRGSsFPYTAKs S412-p
FOXO3A (rat) GLMQRSSSFPYTAKS S412
S419-p
sFPYTAKssGLGsPt
0 1
FOXO3A (human) sFPYTTKGsGLGsPt G420
FOXO3A (mouse) sFPYTAKssGLGsPt S419-p
FOXO3A (rat) SFPYTAKSSGLGSPT S419
S420-p
FPYTAKssGLGsPtG
0 4
FOXO3A (human) FPYTTKGsGLGsPtS S421-p
FOXO3A (mouse) FPYTAKssGLGsPtG S420-p
FOXO3A (rat) FPYTAKSSGLGSPTS S420
S424-p
AKssGLGsPtGsFNs
Upstream
3 10
FOXO3A (human)
S425-p
Regulatory protein:
  • MPRIP (mouse)
FOXO3A (human) TKGsGLGsPtSSFNS S425-p
FOXO3A (mouse) AKssGLGsPtGsFNs S424-p
FOXO3A (rat) AKSSGLGSPTSSFNS S424
T426-p
ssGLGsPtGsFNstV
1 4
FOXO3A (human) GsGLGsPtSSFNSTV T427-p
FOXO3A (mouse) ssGLGsPtGsFNstV T426-p
FOXO3A (rat) SSGLGSPTSSFNSTV T426
S428-p
GLGsPtGsFNstVFG
Upstream
0 1
Regulatory protein:
  • MPRIP (mouse)
FOXO3A (human) GLGsPtSSFNSTVFG S429
FOXO3A (mouse) GLGsPtGsFNstVFG S428-p
FOXO3A (rat) GLGSPTSSFNSTVFG S428
S431-p
sPtGsFNstVFGPSS
0 1
FOXO3A (human) sPtSSFNSTVFGPSs S432
FOXO3A (mouse) sPtGsFNstVFGPSS S431-p
FOXO3A (rat) SPTSSFNSTVFGPAS S431
T432-p
PtGsFNstVFGPSSL
0 1
FOXO3A (human) PtSSFNSTVFGPSsL T433
FOXO3A (mouse) PtGsFNstVFGPSSL T432-p
FOXO3A (rat) PTSSFNSTVFGPASL T432
S438
stVFGPSSLNSLRQS
0 1
FOXO3A (human) STVFGPSsLNSLRQS S439-p
FOXO3A (mouse) stVFGPSSLNSLRQS S438
FOXO3A (rat) STVFGPASLNSLRQS S438
S550
LGGSRALSNSVSNMG
0 2
FOXO3A (human) LGGSRALsNsVsNMG S551-p
FOXO3A (mouse) LGGSRALSNSVSNMG S550
FOXO3A (rat) LGGSRALSNSVSNMG S550
S552
GSRALSNSVSNMGLS
0 1
FOXO3A (human) GSRALsNsVsNMGLS S553-p
FOXO3A (mouse) GSRALSNSVSNMGLS S552
FOXO3A (rat) GSRALSNSVSNMGLS S552
S554
RALSNSVSNMGLSDS
2 1
FOXO3A (human) RALsNsVsNMGLSES S555-p
FOXO3A (mouse) RALSNSVSNMGLSDS S554
FOXO3A (rat) RALSNSVSNMGLSDS S554
K568-ac
SSSLGSAkHQQQsPA
3 0
FOXO3A (human) SSSLGSAkHQQQsPV K569-ac
FOXO3A (mouse) SSSLGSAkHQQQsPA K568-ac
FOXO3A (rat) SSSLGSAKHQQQSPV K568
S573-p
SAkHQQQsPASQSMQ
4 2
FOXO3A (human) SAkHQQQsPVSQSMQ S574-p
FOXO3A (mouse) SAkHQQQsPASQSMQ S573-p
FOXO3A (rat) SAKHQQQSPVSQSMQ S573
S587
QTLSDSLSGSSLYSA
2 1
FOXO3A (human) QTLSDSLsGSSLYST S588-p
FOXO3A (mouse) QTLSDSLSGSSLYSA S587
FOXO3A (rat) QTLSDSLSGSSLYSA S587
S625
SLECDMESIIRSELM
3 1
FOXO3A (human) SLECDMEsIIRSELM S626-p
FOXO3A (mouse) SLECDMESIIRSELM S625
FOXO3A (rat) SLECDMESIIRSELM S625
S643
GLDFNFDSLISTQNV
2 0
FOXO3A (human) GLDFNFDsLISTQNV S644-p
FOXO3A (mouse) GLDFNFDSLISTQNV S643
FOXO3A (rat) GLDFNFDSLISTQNV S643