Other Species / Isoforms
  MSK2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T22-p
RITEANLtGHEEkVs
0 3
MSK2 (human) RITEANLtGHEEkVs T22-p
MSK2 iso2 (human) RITEANLTGHEEKVS T22
MSK2 (mouse) QITEANLTGHEEKVS T22
MSK2 (rat) QITEANLTGHEEKVS T22
K27-ub
NLtGHEEkVsVENFE
0 1
MSK2 (human) NLtGHEEkVsVENFE K27-ub
MSK2 iso2 (human) NLTGHEEKVSVENFE K27
MSK2 (mouse) NLTGHEEKVSVENFA K27
MSK2 (rat) NLTGHEEKVSVENFA K27
S29-p
tGHEEkVsVENFELL
0 1
MSK2 (human) tGHEEkVsVENFELL S29-p
MSK2 iso2 (human) TGHEEKVSVENFELL S29
MSK2 (mouse) TGHEEKVSVENFALL S29
MSK2 (rat) TGHEEKVSVENFALL S29
K37-ub
VENFELLkVLGtGAy
Upstream
0 3
Treatment
  • MG132
MSK2 (human) VENFELLkVLGtGAy K37-ub
MSK2 iso2 (human) VENFELLKVLGTGAY K37
MSK2 (mouse) VENFALLKVLGTGAY K37
MSK2 (rat) VENFALLKVLGTGAY K37
T41-p
ELLkVLGtGAyGKVF
0 1
MSK2 (human) ELLkVLGtGAyGKVF T41-p
MSK2 iso2 (human) ELLKVLGTGAYGKVF T41
MSK2 (mouse) ALLKVLGTGAYGKVF T41
MSK2 (rat) ALLKVLGTGAYGKVF T41
Y44-p
kVLGtGAyGKVFLVR
0 2
MSK2 (human) kVLGtGAyGKVFLVR Y44-p
MSK2 iso2 (human) KVLGTGAYGKVFLVR Y44
MSK2 (mouse) KVLGTGAYGKVFLVR Y44
MSK2 (rat) KVLGTGAYGKVFLVR Y44
K69-ub
YAMKVLRkAALVQRA
0 1
MSK2 (human) YAMKVLRkAALVQRA K69-ub
MSK2 iso2 (human) YAMKVLRKAALVQRA K69
MSK2 (mouse) YAMKVLRKAALVQRA K69
MSK2 (rat) YAMKVLRKAALVQRA K69
S87-p
EHTRTERsVLELVRQ
0 2
MSK2 (human) EHTRTERsVLELVRQ S87-p
MSK2 iso2 (human) EHTRTERSVLELVRQ S87
MSK2 (mouse) EHTRTERsVLELVRQ S87-p
MSK2 (rat) EHTRTERSVLELVRQ S87
K134-ub
LYQRQYFkEAEVRVy
0 1
MSK2 (human) LYQRQYFkEAEVRVy K134-ub
MSK2 iso2 (human) LYQRQYFKEAEVRVY K134
MSK2 (mouse) LYQRQYFKEAEVRVY K134
MSK2 (rat) LYQRQYFKEAEVRVY K134
Y141-p
kEAEVRVyGGEIVLA
0 1
MSK2 (human) kEAEVRVyGGEIVLA Y141-p
MSK2 iso2 (human) KEAEVRVYGGEIVLA Y141
MSK2 (mouse) KEAEVRVYGGEIVLA Y141
MSK2 (rat) KEAEVRVYGGEIVLA Y141
R160
HKLGIIYRDLKLENV
0 2
MSK2 (human) HKLGIIYRDLKLENV R160
MSK2 iso2 (human) HKLGIIYRDLKLENV R160
MSK2 (mouse) HKLGIIYrDLKLENV R160-m1
MSK2 (rat) HKLGIIYRDLKLENV R160
S183-p
VLTDFGLskEFLTEE
0 2
MSK2 (human) VLTDFGLskEFLTEE S183-p
MSK2 iso2 (human) VLTDFGLSKEFLTEE S183
MSK2 (mouse) VLTDFGLsKEFLTEE S183-p
MSK2 (rat) VLTDFGLSKEFLTEE S183
K184-ub
LTDFGLskEFLTEEk
0 1
MSK2 (human) LTDFGLskEFLTEEk K184-ub
MSK2 iso2 (human) LTDFGLSKEFLTEEK K184
MSK2 (mouse) LTDFGLsKEFLTEEK K184
MSK2 (rat) LTDFGLSKEFLTEEK K184
K191-ub
kEFLTEEkERtFsFC
0 1
MSK2 (human) kEFLTEEkERtFsFC K191-ub
MSK2 iso2 (human) KEFLTEEKERTFSFC K191
MSK2 (mouse) KEFLTEEKERTFSFC K191
MSK2 (rat) KEFLTEEKERTFSFC K191
T194-p
LTEEkERtFsFCGTI
0 1
MSK2 (human) LTEEkERtFsFCGTI T194-p
MSK2 iso2 (human) LTEEKERTFSFCGTI T194
MSK2 (mouse) LTEEKERTFSFCGTI T194
MSK2 (rat) LTEEKERTFSFCGTI T194
S196-p
EEkERtFsFCGTIEY
Upstream
Downstream
4 2
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • MSK2 (human)
  • P38A (human)
Treatment
  • anisomycin
  • dimethylfumarate
  • fumaric_acid
  • IL-1b
  • methylhydrogenfumarate
  • SB202190
  • UV
view more >
MSK2 (human) EEkERtFsFCGTIEY S196-p
MSK2 iso2 (human) EEKERTFSFCGTIEY S196
MSK2 (mouse) EEKERTFSFCGTIEY S196
MSK2 (rat) EEKERTFSFCGTIEY S196
K313-ub
WVALAARkIPAPFRP
0 1
MSK2 (human) WVALAARkIPAPFRP K313-ub
MSK2 iso2 (human) WVALAARKIPAPFRP K313
MSK2 (mouse) WVALAARKIPAPFRP K313
MSK2 (rat) WVALAARKIPAPFRP K313
S324-p
PFRPQIRsELDVGNF
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Kinase, in vitro:
  • CK2A1 (human)
MSK2 (human) PFRPQIRsELDVGNF S324-p
MSK2 iso2 (human) PFRPQIRSELDVGNF S324
MSK2 (mouse) PFRPQIRSELDVGNF S324
MSK2 (rat) PFRPQIRSELDVGNF S324
Y342-p
FTRLEPVysPPGsPP
0 1
MSK2 (human) FTRLEPVysPPGsPP Y342-p
MSK2 iso2 (human) FTRLEPVYSPPGSPP Y342
MSK2 (mouse) FTRLEPVYsPAGsPP Y342
MSK2 (rat) FTRLEPVYsPAGsPP Y342
S343-p
TRLEPVysPPGsPPP
Upstream
Downstream
1 40
Effects on Modified Protein
  • enzymatic activity, induced
Regulatory protein:
  • CD38 (human)
Treatment
  • EGF
  • ischemia
  • MG132_withdrawal
  • SB202190
  • U0126
view more >
MSK2 (human) TRLEPVysPPGsPPP S343-p
MSK2 iso2 (human) TRLEPVYSPPGSPPP S343
MSK2 (mouse) TRLEPVYsPAGsPPP S343-p
MSK2 (rat) TRLEPVYsPAGsPPP S343-p
S347-p
PVysPPGsPPPGDPR
Upstream
Downstream
1 44
Effects on Modified Protein
  • enzymatic activity, induced
Regulatory protein:
  • CD38 (human)
  • MKK6 (mouse)
  • P38A (human)
view more >
Treatment
  • EGF
  • ionomycin
  • ischemia
  • MG132_withdrawal
  • PD98059
  • SB202190
  • TNF
  • U0126
  • vemurafenib
view more >
MSK2 (human) PVysPPGsPPPGDPR S347-p
MSK2 iso2 (human) PVYSPPGSPPPGDPR S347
MSK2 (mouse) PVYsPAGsPPPGDPR S347-p
MSK2 (rat) PVYsPAGsPPPGDPR S347-p
Y359-p
DPRIFQGysFVAPsI
0 3
MSK2 (human) DPRIFQGysFVAPsI Y359-p
MSK2 iso2 (human) DPRIFQGYSFVAPSI Y359
MSK2 (mouse) DPRIFQGYSFVAPSI Y359
MSK2 (rat) DPRIFQGYSFVAPSI Y359
S360-p
PRIFQGysFVAPsIL
Upstream
Downstream
2 13
Effects on Modified Protein
  • enzymatic activity, induced
Regulatory protein:
  • MKK6 (mouse)
  • P38A (human)
Treatment
  • ionomycin
  • PD98059
  • SB202190
  • TNF
view more >
MSK2 (human) PRIFQGysFVAPsIL S360-p
MSK2 iso2 (human) PRIFQGYSFVAPSIL S360
MSK2 (mouse) PRIFQGYSFVAPSIL S360
MSK2 (rat) PRIFQGYSFVAPSIL S360
S365-p
GysFVAPsILFDHNN
0 6
MSK2 (human) GysFVAPsILFDHNN S365-p
MSK2 iso2 (human) GYSFVAPSILFDHNN S365
MSK2 (mouse) GYSFVAPSILFDHNN S365
MSK2 (rat) GYSFVAPSILFDHNN S365
T376-p
DHNNAVMtDGLEAPG
0 3
MSK2 (human) DHNNAVMtDGLEAPG T376-p
MSK2 iso2 (human) DHNNAVMTDGLEAPG T376
MSK2 (mouse) DHNNAVMADVLQAPG A376
MSK2 (rat) DHNNAVMADVLAAPG A376
K440-ub
SGQEFAVkILSRRLE
Upstream
0 1
Treatment
  • MG132
MSK2 (human) SGQEFAVkILSRRLE K440-ub
MSK2 iso2 (human) SGQEFAVKILSRRLE K434
MSK2 (mouse) SGQEFAVKILSRRLE K440
MSK2 (rat) SGQEFAVKILSRRLE K440
S502-p
IRKKRHFsESEASQI
0 2
MSK2 (human) IRKKRHFsESEASQI S502-p
MSK2 iso2 (human) IRKKRHFSESEASQI S496
MSK2 (mouse) IRKKRLFsEsEAsQI S502-p
MSK2 (rat) IRKKRLFSESEASQI S502
S504
KKRHFsESEASQILR
0 1
MSK2 (human) KKRHFsESEASQILR S504
MSK2 iso2 (human) KKRHFSESEASQILR S498
MSK2 (mouse) KKRLFsEsEAsQILR S504-p
MSK2 (rat) KKRLFSESEASQILR S504
S507
HFsESEASQILRSLV
0 1
MSK2 (human) HFsESEASQILRSLV S507
MSK2 iso2 (human) HFSESEASQILRSLV S501
MSK2 (mouse) LFsEsEAsQILRSLV S507-p
MSK2 (rat) LFSESEASQILRSLV S507
K532-ub
GVVHRDLkPENILYA
0 3
MSK2 (human) GVVHRDLkPENILYA K532-ub
MSK2 iso2 (human) GVVHRDLKPENILYA K526
MSK2 (mouse) GVVHRDLKPENILYA K532
MSK2 (rat) GVVHRDLKPENILYA K532
T542-p
NILYADDtPGAPVkI
0 5
MSK2 (human) NILYADDtPGAPVkI T542-p
MSK2 iso2 (human) NILYADDTPGAPVKI T536
MSK2 (mouse) NILYADDtPGAPVKI T542-p
MSK2 (rat) NILYADDTPGAPVKI T542
K548-ub
DtPGAPVkIIDFGFA
0 1
MSK2 (human) DtPGAPVkIIDFGFA K548-ub
MSK2 iso2 (human) DTPGAPVKIIDFGFA K542
MSK2 (mouse) DtPGAPVKIIDFGFA K548
MSK2 (rat) DTPGAPVKIIDFGFA K548
T568-p
SPGVPMQtPCFTLQY
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
MSK2 (human) SPGVPMQtPCFTLQY T568-p
MSK2 iso2 (human) SPGVPMQTPCFTLQY T562
MSK2 (mouse) SPAEPMQTPCFTLQY T568
MSK2 (rat) SPAGPMQTPCFTLQY T568
S634-p
KIREGRFsLDGEAWQ
0 2
MSK2 (human) KIREGRFsLDGEAWQ S634-p
MSK2 iso2 (human) KIREGRFSLDGEAWQ S628
MSK2 (mouse) KIREGRFSLDGEAWQ S634
MSK2 (rat) KIREGRFSLDGEAWQ S634
K648-ub
QGVSEEAkELVRGLL
0 1
MSK2 (human) QGVSEEAkELVRGLL K648-ub
MSK2 iso2 (human) QGVSEEAKELVRGLL K642
MSK2 (mouse) QGVSEEAKELVRGLL K648
MSK2 (rat) QGVSEEAKELVRGLL K648
K661-ub
LLTVDPAkRLkLEGL
0 2
MSK2 (human) LLTVDPAkRLkLEGL K661-ub
MSK2 iso2 (human) LLTVDPAKRLKLEGL K655
MSK2 (mouse) LLTVDPAKRLKLEGL K661
MSK2 (rat) LLTVDPAKRLKLEGL K661
K664-sm
VDPAkRLkLEGLRGS
0 1
MSK2 (human) VDPAkRLkLEGLRGS K664-sm
MSK2 iso2 (human) VDPAKRLKLEGLRGS K658
MSK2 (mouse) VDPAKRLKLEGLRSS K664
MSK2 (rat) VDPAKRLKLEGLRSS K664
K664-ub
VDPAkRLkLEGLRGS
0 1
MSK2 (human) VDPAkRLkLEGLRGS K664-ub
MSK2 iso2 (human) VDPAKRLKLEGLRGS K658
MSK2 (mouse) VDPAKRLKLEGLRSS K664
MSK2 (rat) VDPAKRLKLEGLRSS K664
S672
LEGLRGSSWLQDGsA
0 1
MSK2 (human) LEGLRGSSWLQDGsA S672
MSK2 iso2 (human) LEGLRGSSWLQDGSA S666
MSK2 (mouse) LEGLRSSsWLQDGsA S672-p
MSK2 (rat) LEGLRSSSWLQDGSA S672
S678-p
SSWLQDGsARssPPL
Upstream
0 11
Treatment
  • MG132
  • MG132_withdrawal
MSK2 (human) SSWLQDGsARssPPL S678-p
MSK2 iso2 (human) SSWLQDGSARSSPPL S672
MSK2 (mouse) SsWLQDGsARssPPL S678-p
MSK2 (rat) SSWLQDGSARSSPPL S678
S681-p
LQDGsARssPPLRtP
0 5
MSK2 (human) LQDGsARssPPLRtP S681-p
MSK2 iso2 (human) LQDGSARSSPPLRTP S675
MSK2 (mouse) LQDGsARssPPLRtP S681-p
MSK2 (rat) LQDGSARSSPPLRtP S681
S682-p
QDGsARssPPLRtPD
0 11
MSK2 (human) QDGsARssPPLRtPD S682-p
MSK2 iso2 (human) QDGSARSSPPLRTPD S676
MSK2 (mouse) QDGsARssPPLRtPD S682-p
MSK2 (rat) QDGSARSSPPLRtPD S682
T687-p
RssPPLRtPDVLESS
Upstream
Downstream
1 30
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • BI2536
  • ischemia
  • metformin
view more >
MSK2 (human) RssPPLRtPDVLESS T687-p
MSK2 iso2 (human) RSSPPLRTPDVLESS T681
MSK2 (mouse) RssPPLRtPDVLESS T687-p
MSK2 (rat) RSSPPLRtPDVLESS T687-p
K720-ub
KREGFFLksVENAPL
0 1
MSK2 (human) KREGFFLksVENAPL K720-ub
MSK2 iso2 (human) KREGFFLKSVENAPL K714
MSK2 (mouse) KREGFFLKSVENAPL K720
MSK2 (rat) KREGFFLKSVENAPL K720
S721-p
REGFFLksVENAPLA
Upstream
0 6
Treatment
  • MG132_withdrawal
MSK2 (human) REGFFLksVENAPLA S721-p
MSK2 iso2 (human) REGFFLKSVENAPLA S715
MSK2 (mouse) REGFFLKSVENAPLA S721
MSK2 (rat) REGFFLKSVENAPLA S721
K729-ub
VENAPLAkRRKQKLR
0 1
MSK2 (human) VENAPLAkRRKQKLR K729-ub
MSK2 iso2 (human) VENAPLAKRRKQKLR K723
MSK2 (mouse) VENAPLAKRRKQKLR K729
MSK2 (rat) VENAPLAKRRKQKLR K729
S737-p
RRKQKLRsATASRrG
Upstream
0 6
Treatment
  • MG132_withdrawal
MSK2 (human) RRKQKLRsATASRrG S737-p
MSK2 iso2 (human) RRKQKLRSATASRRG S731
MSK2 (mouse) RRKQKLRsAAASRRG S737-p
MSK2 (rat) RRKQKLRSAAASRRG S737
R743-m1
RsATASRrGsPAPAN
0 9
MSK2 (human) RsATASRrGsPAPAN R743-m1
MSK2 iso2 (human) RSATASRRGSPAPAN R737
MSK2 (mouse) RsAAASRRGsPVPAS R743
MSK2 (rat) RSAAASRRGsPVPAS R743
S745-p
ATASRrGsPAPANPG
Upstream
0 29
Regulatory protein:
  • CD38 (human)
Treatment
  • ischemia
  • MG132_withdrawal
MSK2 (human) ATASRrGsPAPANPG S745-p
MSK2 iso2 (human) ATASRRGSPAPANPG S739
MSK2 (mouse) AAASRRGsPVPASSG S745-p
MSK2 (rat) AAASRRGsPVPASSG S745-p
-
gap
0 2
MSK2 (human) gap -
MSK2 iso2 (human) gap -
MSK2 (mouse) SSGRLPAsAAKGTTR S757-p
MSK2 (rat) SSGRLPASASKGTTR S757
P770
RRANGPLPPs_____
0 3
MSK2 (human) RRANGPLPPs_____ P770
MSK2 iso2 (human) RRANGPLPPS_____ P764
MSK2 (mouse) RRANGPLsPS_____ S771-p
MSK2 (rat) RRANGPLSPS_____ S771
S772-p
ANGPLPPs_______
Upstream
0 2
Treatment
  • MG132_withdrawal
MSK2 (human) ANGPLPPs_______ S772-p
MSK2 iso2 (human) ANGPLPPS_______ S766
MSK2 (mouse) ANGPLsPS_______ S773
MSK2 (rat) ANGPLSPS_______ S773