Other Species / Isoforms
  PRKD1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y95
KFPECGFyGMYDKIL
Upstream
Downstream
3 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Putative in vivo kinases:
  • Src (human)
Treatment
  • H2O2
  • phorbol_ester
  • PP2
PRKD1 (human) KFPECGFyGMYDKIL Y95
PRKD1 (mouse) KFPECGFyGLYDKIL Y93
PRKD1 (rat) KFPECGFYGLYDKIL Y93
S205
GVRRRRLsNVsLtGV
Upstream
Downstream
7 119
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • angiotensin_2
  • Go_6976
  • Go_6983
  • H2O2
  • ischemia
  • LPA
  • PGE2
  • SII_angiotensin_2
PRKD1 (human) GVRRRRLsNVsLtGV S205
PRKD1 (mouse) GVRRRRLsNVsLTGL S203
PRKD1 (rat) GVRRRRLsNVsLTGL S203
S208
RRRLsNVsLtGVSTI
Upstream
Downstream
2 34
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • PRKD1 (human)
Treatment
  • angiotensin_2
  • Go_6976
  • Go_6983
  • H2O2
  • ischemia
  • LPA
  • SII_angiotensin_2
PRKD1 (human) RRRLsNVsLtGVSTI S208
PRKD1 (mouse) RRRLsNVsLTGLGtV S206
PRKD1 (rat) RRRLsNVsLTGLGTV S206
T210
RLsNVsLtGVSTIRt
Upstream
0 8
Treatment
  • angiotensin_2
  • SII_angiotensin_2
PRKD1 (human) RLsNVsLtGVSTIRt T210
PRKD1 (mouse) RLsNVsLTGLGtVRT T208
PRKD1 (rat) RLsNVsLTGLGTVRT T208
T214
VsLtGVSTIRtSsAE
0 1
PRKD1 (human) VsLtGVSTIRtSsAE T214
PRKD1 (mouse) VsLTGLGtVRTASAE T212
PRKD1 (rat) VsLTGLGTVRTASAE T212
T217
tGVSTIRtSsAELst
0 5
PRKD1 (human) tGVSTIRtSsAELst T217
PRKD1 (mouse) TGLGtVRTASAEFST T215
PRKD1 (rat) TGLGTVRTASAEFST T215
S219
VSTIRtSsAELstsA
Upstream
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • Go_6976
  • Go_6983
  • H2O2
PRKD1 (human) VSTIRtSsAELstsA S219
PRKD1 (mouse) LGtVRTASAEFSTSV S217
PRKD1 (rat) LGTVRTASAEFSTSA S217
S223
RtSsAELstsAPDEP
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • Go_6976
  • Go_6983
  • H2O2
PRKD1 (human) RtSsAELstsAPDEP S223
PRKD1 (mouse) RTASAEFSTSVPDEP S221
PRKD1 (rat) RTASAEFSTSAPDEP S221
T224
tSsAELstsAPDEPL
0 1
PRKD1 (human) tSsAELstsAPDEPL T224
PRKD1 (mouse) TASAEFSTSVPDEPL T222
PRKD1 (rat) TASAEFSTSAPDEPL T222
S225
SsAELstsAPDEPLL
Upstream
0 1
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) SsAELstsAPDEPLL S225
PRKD1 (mouse) ASAEFSTSVPDEPLL S223
PRKD1 (rat) ASAEFSTSAPDEPLL S223
S235
DEPLLQKsPsEsFIG
Upstream
0 8
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) DEPLLQKsPsEsFIG S235
PRKD1 (mouse) SPGFEQKsPsESFIG S241
PRKD1 (rat) SPGFEQKSPSESFIG S241
S237
PLLQKsPsEsFIGRE
Upstream
0 9
Regulatory protein:
  • PRKD1 (human)
Treatment
  • angiotensin_2
  • LPA
PRKD1 (human) PLLQKsPsEsFIGRE S237
PRKD1 (mouse) GFEQKsPsESFIGRE S243
PRKD1 (rat) GFEQKSPSESFIGRE S243
S239
LQKsPsEsFIGREKR
0 1
PRKD1 (human) LQKsPsEsFIGREKR S239
PRKD1 (mouse) EQKsPsESFIGREKR S245
PRKD1 (rat) EQKSPSESFIGREKR S245
S247
FIGREKRsNsQSYIG
Upstream
0 3
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) FIGREKRsNsQSYIG S247
PRKD1 (mouse) FIGREKRsNsQSYIG S253
PRKD1 (rat) FIGREKRSNSQSYVG S253
S249
GREKRsNsQSYIGRP
Upstream
2 15
Regulatory protein:
  • PRKD1 (human)
Treatment
  • ischemia
  • LPA
PRKD1 (human) GREKRsNsQSYIGRP S249
PRKD1 (mouse) GREKRsNsQSYIGRP S255
PRKD1 (rat) GREKRSNSQSYVGRP S255
S345
DVVMEEGsDDNDSER
0 1
PRKD1 (human) DVVMEEGsDDNDSER S345
PRKD1 (mouse) DVVMEEGSDDNDSER S351
PRKD1 (rat) DVVMEEGSDDNDSER S351
S379
MAECQNDsGEMQDPD
0 1
PRKD1 (human) MAECQNDsGEMQDPD S379
PRKD1 (mouse) LAEGQSGGAEMQDPD G385
PRKD1 (rat) LAEGQSDGAEMQDPD G385
T395
DHEDANRtIsPStsN
Upstream
0 6
Treatment
  • angiotensin_2
  • SII_angiotensin_2
PRKD1 (human) DHEDANRtIsPStsN T395
PRKD1 (mouse) DQEDSNRtIsPStsN T401
PRKD1 (rat) DQEDSNRTIsPSTSN T401
S397
EDANRtIsPStsNNI
Upstream
1 38
Treatment
  • LPA
PRKD1 (human) EDANRtIsPStsNNI S397
PRKD1 (mouse) EDSNRtIsPStsNNI S403
PRKD1 (rat) EDSNRTIsPSTSNNI S403
T400
NRtIsPStsNNIPLM
0 3
PRKD1 (human) NRtIsPStsNNIPLM T400
PRKD1 (mouse) NRtIsPStsNNIPLM T406
PRKD1 (rat) NRTIsPSTSNNIPLM T406
S401
RtIsPStsNNIPLMR
Upstream
1 21
Regulatory protein:
  • PRKD1 (human)
Treatment
  • angiotensin_2
  • SII_angiotensin_2
PRKD1 (human) RtIsPStsNNIPLMR S401
PRKD1 (mouse) RtIsPStsNNIPLMR S407
PRKD1 (rat) RTIsPSTSNNIPLMR S407
S412
PLMRVVQsVKHTKRK
Upstream
1 1
Kinase, in vitro:
  • PKCA (human)
  • PKCD (human)
Putative in vivo kinases:
  • PKCD (human)
Regulatory protein:
  • PKCD (human)
Treatment
  • endothelin
  • Go_6976
  • Go_6983
  • isoproterenol
  • norepinephrine
  • phenylephrine
  • phorbol_ester
PRKD1 (human) PLMRVVQsVKHTKRK S412
PRKD1 (mouse) PLMRVVQSVKHTKRR S418
PRKD1 (rat) PLMRVVQSVKHTKRR S418
S421
KHTKRKSstVMKEGW
Upstream
2 4
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • 8-Rp-cAMP
  • CID755673
  • H-89
  • isoproterenol
  • NKH_477
PRKD1 (human) KHTKRKSstVMKEGW S421
PRKD1 (mouse) KHTKRRSsTVMKEGW S427
PRKD1 (rat) KHTKRRSSTVMKEGW S427
T422
HTKRKSstVMKEGWM
0 2
PRKD1 (human) HTKRKSstVMKEGWM T422
PRKD1 (mouse) HTKRRSsTVMKEGWM T428
PRKD1 (rat) HTKRRSSTVMKEGWM T428
Y432
KEGWMVHyTSKDTLR
Upstream
1 1
Putative in vivo kinases:
  • Src (human)
PRKD1 (human) KEGWMVHyTSKDTLR Y432
PRKD1 (mouse) KEGWMVHYTSKDTLR Y438
PRKD1 (rat) KEGWMVHYTSKDTLR Y438
Y443
DTLRKRHyWRLDsKC
0 1
PRKD1 (human) DTLRKRHyWRLDsKC Y443
PRKD1 (mouse) DTLRKRHYWRLDSKC Y449
PRKD1 (rat) DTLRKRHYWRLDSKS Y449
S448
RHyWRLDsKCITLFQ
0 1
PRKD1 (human) RHyWRLDsKCITLFQ S448
PRKD1 (mouse) RHYWRLDSKCITLFQ S454
PRKD1 (rat) RHYWRLDSKSITLFQ S454
S460
LFQNDTGsRYyKEIP
0 1
PRKD1 (human) LFQNDTGsRYyKEIP S460
PRKD1 (mouse) LFQNDTGSRYyKEIP S466
PRKD1 (rat) LFQNDTGSRYYKEIP S466
Y463
NDTGsRYyKEIPLSE
Upstream
Downstream
7 0
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell differentiation, altered
  • cell growth, altered
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • Abl (human)
Putative in vivo kinases:
  • Abl (human)
  • Src (human)
Treatment
  • bradykinin
  • H2O2
  • phorbol_ester
  • resveratrol
  • vanadate
  • VEGF
PRKD1 (human) NDTGsRYyKEIPLSE Y463
PRKD1 (mouse) NDTGSRYyKEIPLSE Y469
PRKD1 (rat) NDTGSRYYKEIPLSE Y469
S473
IPLSEILsLEPVKTS
0 3
PRKD1 (human) IPLSEILsLEPVKTS S473
PRKD1 (mouse) IPLSEILCLEPAKPS C479
PRKD1 (rat) IPLSEILCLEPAKPS C479
Y502
TTANVVYyVGENVVN
Upstream
1 0
Putative in vivo kinases:
  • Src (human)
PRKD1 (human) TTANVVYyVGENVVN Y502
PRKD1 (mouse) TTANVVYYVGENVVN Y508
PRKD1 (rat) TTANVVYYVGENVVN Y508
S548
MPVIPKGssVGTGTN
Upstream
0 3
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) MPVIPKGssVGTGTN S548
PRKD1 (mouse) MPVIPKGSSVGSGSN S554
PRKD1 (rat) MPVIPKGSSVGSGTN S554
S549
PVIPKGssVGTGTNL
0 4
PRKD1 (human) PVIPKGssVGTGTNL S549
PRKD1 (mouse) PVIPKGSSVGSGSNS S555
PRKD1 (rat) PVIPKGSSVGSGTNS S555
S738
ARIIGEKsFRRsVVG
Upstream
Downstream
57 33
PRKD1 (human)
S738
PRKD1 (mouse)
S744
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
  • cell differentiation, altered
  • cell growth, induced
  • cell motility, altered
  • signaling pathway regulation
  • transcription, altered
Kinase, in vitro:
  • PKCA (human)
  • PKCD (human)
  • PKCE (human)
  • PKCH (human)
Putative in vivo kinases:
  • PKCA (human)
  • PKCD (human)
  • PKCH (human)
  • PRKD1 (human)
  • PRKD3 (human)
Regulatory protein:
  • Abl (human)
  • AKAP13 (human)
  • PKCD (human)
  • PRKD1 (human)
  • Src (human)
Treatment
  • anti-CD3/CD28
  • anti-IgM
  • aphidicolin
  • arachidonic_acid
  • ATP
  • BAPTA-AM
  • bisindolylmaleimide
  • bombesin
  • bradykinin
  • BSO
  • CID755673
  • colforsin
  • DTBR
  • EGF
  • endothelin
  • exercise
  • fibronectin
  • GF109203X
  • Go_6976
  • Go_6983
  • H-89
  • H2O2
  • HB-EGF
  • IBMX
  • IGF-1
  • isoproterenol
  • LPA
  • neurotensin
  • nocodazole
  • norepinephrine
  • PDGF
  • phenylephrine
  • phorbol_ester
  • polyHEMA
  • resveratrol
  • RO-3306
  • Ro31-8220
  • salicylate
  • STLC
  • taxol
  • TeTx
  • TGF-beta
  • thrombin
  • U73122
  • U73343
  • vanadate
  • vasopressin
  • VEGF
  • virus infection
  • wortmannin
  • ZM447439
PRKD1 (human) ARIIGEKsFRRsVVG S738
PRKD1 (mouse) ARIIGEKsFRRsVVG S744
PRKD1 (rat) ARIIGEKsFRRsVVG S744
S742
GEKsFRRsVVGtPAy
Upstream
Downstream
56 99
PRKD1 (mouse)
S748
Effects on Modified Protein
  • enzymatic activity, induced
  • enzymatic activity, inhibited
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
  • cell differentiation, altered
  • cell growth, induced
  • cell motility, altered
  • signaling pathway regulation
  • transcription, altered
Kinase, in vitro:
  • PKCA (human)
  • PKCD (human)
  • PKCE (human)
  • PKCH (human)
Putative in vivo kinases:
  • PKCA (human)
  • PKCD (human)
  • PKCH (human)
  • PRKD1 (human)
  • PRKD3 (human)
Regulatory protein:
  • Abl (human)
  • AKAP13 (human)
  • PKCD (human)
  • PRKD1 (human)
  • Src (human)
Treatment
  • anti-CD3/CD28
  • anti-IgM
  • arachidonic_acid
  • ATP
  • BAPTA-AM
  • bisindolylmaleimide
  • bombesin
  • bradykinin
  • BSO
  • CID755673
  • colforsin
  • DTBR
  • EGF
  • endothelin
  • exercise
  • fibronectin
  • GF109203X
  • Go_6976
  • Go_6983
  • H2O2
  • HB-EGF
  • IBMX
  • IGF-1
  • isoproterenol
  • LPA
  • neurotensin
  • nocodazole
  • norepinephrine
  • PDGF
  • phenylephrine
  • phorbol_ester
  • polyHEMA
  • resveratrol
  • RO-3306
  • Ro31-8220
  • salicylate
  • STLC
  • taxol
  • TGF-beta
  • thrombin
  • TNF
  • U73122
  • U73343
  • vanadate
  • vasopressin
  • VEGF
  • virus infection
  • wortmannin
PRKD1 (human) GEKsFRRsVVGtPAy S742
PRKD1 (mouse) GEKsFRRsVVGtPAy S748
PRKD1 (rat) GEKsFRRsVVGTPAY S748
T746
FRRsVVGtPAyLAPE
Upstream
0 22
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) FRRsVVGtPAyLAPE T746
PRKD1 (mouse) FRRsVVGtPAyLAPE T752
PRKD1 (rat) FRRsVVGTPAYLAPE T752
Y749
sVVGtPAyLAPEVLR
0 8
PRKD1 (human) sVVGtPAyLAPEVLR Y749
PRKD1 (mouse) sVVGtPAyLAPEVLR Y755
PRKD1 (rat) sVVGTPAYLAPEVLR Y755
S890
HLINPSAsHsDTPET
0 1
PRKD1 (human) HLINPSAsHsDTPET S890
PRKD1 (mouse) HLISLSASHSDSPEA S896
PRKD1 (rat) HLINLSASHGDSPEA S896
S892
INPSAsHsDTPETEE
Upstream
0 1
Regulatory protein:
  • PRKD1 (human)
PRKD1 (human) INPSAsHsDTPETEE S892
PRKD1 (mouse) ISLSASHSDSPEAEE S898
PRKD1 (rat) INLSASHGDSPEAEE G898
S910
KALGERVsIL_____
Upstream
Downstream
41 13
PRKD1 (human)
S910
PRKD1 (mouse)
S916
Effects on Modified Protein
  • enzymatic activity, induced
  • enzymatic activity, inhibited
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • PRKD1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
  • PRKD1 (mouse)
Regulatory protein:
  • PLCE1 (human)
Treatment
  • AFN700
  • anti-CD3
  • anti-IgM
  • arachidonic_acid
  • ATP
  • BAA473
  • bisindolylmaleimide
  • bombesin
  • bryostatin_1
  • carbachol
  • CGP044892
  • CID755673
  • CRT0066101
  • endothelin
  • fibronectin
  • genistein
  • GF109203X
  • Go_6976
  • Go_6983
  • gramicidin
  • H2O2
  • ischemia
  • isoproterenol
  • kb_NB_142-70
  • LPA
  • MCC950
  • MSU crystals
  • neurotensin
  • niclosamide
  • nigericin
  • norepinephrine
  • PD98059
  • phenylephrine
  • phorbol_ester
  • polyHEMA
  • rapamycin
  • resveratrol
  • salicylate
  • Salmonella typhimurium PrgI protein
  • SB203580
  • serum
  • siRNA
  • thrombin
  • virus infection
  • wortmannin
PRKD1 (human) KALGERVsIL_____ S910
PRKD1 (mouse) KALSERVsIL_____ S916
PRKD1 (rat) KALSERVsIL_____ S916