Other Species / Isoforms
  CYLD (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S3-p
_____MSsGLWSQEk
0 1
CYLD (human) _____MSsGLWSQEk S3-p
CYLD (mouse) _____MSSGLWSQEK S3
CYLD (rat) _____MSSGLWNQEK S3
K10-ub
sGLWSQEkVtsPyWE
0 1
CYLD (human) sGLWSQEkVtsPyWE K10-ub
CYLD (mouse) SGLWSQEKVTsPyWE K10
CYLD (rat) SGLWNQEKVTSPyWE K10
T12-p
LWSQEkVtsPyWEER
0 1
CYLD (human) LWSQEkVtsPyWEER T12-p
CYLD (mouse) LWSQEKVTsPyWEER T12
CYLD (rat) LWNQEKVTSPyWEER T12
S13-p
WSQEkVtsPyWEERI
0 5
CYLD (human) WSQEkVtsPyWEERI S13-p
CYLD (mouse) WSQEKVTsPyWEERI S13-p
CYLD (rat) WNQEKVTSPyWEERL S13
Y15-p
QEkVtsPyWEERIFy
Upstream
Downstream
1 6
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Treatment
  • EGF
CYLD (human) QEkVtsPyWEERIFy Y15-p
CYLD (mouse) QEKVTsPyWEERIFY Y15-p
CYLD (rat) QEKVTSPyWEERLFY Y15-p
Y22-p
yWEERIFyLLLQECs
0 1
CYLD (human) yWEERIFyLLLQECs Y22-p
CYLD (mouse) yWEERIFYLLLQECS Y22
CYLD (rat) yWEERLFYLLLQECS Y22
S29-p
yLLLQECsVtDKQtQ
0 1
CYLD (human) yLLLQECsVtDKQtQ S29-p
CYLD (mouse) YLLLQECSVTDKQTQ S29
CYLD (rat) YLLLQECSVTDKQTQ S29
T31-p
LLQECsVtDKQtQKL
0 1
CYLD (human) LLQECsVtDKQtQKL T31-p
CYLD (mouse) LLQECSVTDKQTQKL T31
CYLD (rat) LLQECSVTDKQTQKL T31
T35-p
CsVtDKQtQKLLkVP
0 1
CYLD (human) CsVtDKQtQKLLkVP T35-p
CYLD (mouse) CSVTDKQTQKLLKVP T35
CYLD (rat) CSVTDKQTQKLLRVP T35
K40-ub
KQtQKLLkVPkGsIG
0 1
CYLD (human) KQtQKLLkVPkGsIG K40-ub
CYLD (mouse) KQTQKLLKVPKGSIG K40
CYLD (rat) KQTQKLLRVPkGSIG R40
K43-ub
QKLLkVPkGsIGQYI
0 3
CYLD (human) QKLLkVPkGsIGQYI K43-ub
CYLD (mouse) QKLLKVPKGSIGQYI K43
CYLD (rat) QKLLRVPkGSIGQYI K43-ub
S45-p
LLkVPkGsIGQYIQD
0 2
CYLD (human) LLkVPkGsIGQYIQD S45-p
CYLD (mouse) LLKVPKGSIGQYIQD S45
CYLD (rat) LLRVPkGSIGQYIQD S45
K73-ub
KKNQIGLkILEQPHA
0 1
CYLD (human) KKNQIGLkILEQPHA K73-ub
CYLD (mouse) KKNQIGLKILEQPHA K73
CYLD (rat) KKNQIGLKILEQPHA K73
K114-ub
EERFSLFkNRNRLSk
0 2
CYLD (human) EERFSLFkNRNRLSk K114-ub
CYLD (mouse) EERLSLFRNRLRLSK R114
CYLD (rat) EERLSLFRNRIRLSk R114
K121-ub
kNRNRLSkGLQIDVG
0 4
CYLD (human) kNRNRLSkGLQIDVG K121-ub
CYLD (mouse) RNRLRLSKGLQVDVG K121
CYLD (rat) RNRIRLSkGLQVDVG K121-ub
K132-ub
IDVGCPVkVQLRSGE
0 1
CYLD (human) IDVGCPVkVQLRSGE K132-ub
CYLD (mouse) VDVGSPVKVQLRSGE K132
CYLD (rat) VDVGSPVRVQLRSGE R132
K141-ub
QLRSGEEkFPGVVRF
0 2
CYLD (human) QLRSGEEkFPGVVRF K141-ub
CYLD (mouse) QLRSGEEKFPGVVRF K141
CYLD (rat) QLRSGEEKFPGVVRF K141
Y181
QGFTDGVYQGKQLFQ
0 7
CYLD (human) QGFTDGVYQGKQLFQ Y181
CYLD (mouse) QGFTDGVYQGKQLFQ Y181
CYLD (rat) QGFTDGVyQGKQLFQ Y181-p
S287-p
FDGVQLCsFACVEST
0 1
CYLD (human) FDGVQLCsFACVEST S287-p
CYLD (mouse) FDGVQLCSFASVEST S287
CYLD (rat) FDGVQLCSFASVEST S287
K318-ub
TQERRPPkLAFMSRG
0 2
CYLD (human) TQERRPPkLAFMSRG K318-ub
CYLD (mouse) TQERRPPKLAFMSRG K315
CYLD (rat) TQERRPPKLAFMSRG K315
K338-ub
SSSHNKPkATGStsD
Downstream
1 1
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • signaling pathway regulation
CYLD (human) SSSHNKPkATGStsD K338-ub
CYLD (mouse) SSSHNKPkVTGSTSD K335-ub
CYLD (rat) SSSHNKPKVTGSTSD K335
T343-p
KPkATGStsDPGNRN
0 2
CYLD (human) KPkATGStsDPGNRN T343-p
CYLD (mouse) KPkVTGSTSDPGSRN T340
CYLD (rat) KPKVTGSTSDPGSRN T340
S344-p
PkATGStsDPGNRNR
0 2
CYLD (human) PkATGStsDPGNRNR S344-p
CYLD (mouse) PkVTGSTSDPGSRNR S341
CYLD (rat) PKVTGSTSDPGSRNR S341
Y356-p
RNRSELFyTLNGSsV
0 3
CYLD (human) RNRSELFyTLNGSsV Y356-p
CYLD (mouse) RNRSELFYTLNGSSV Y353
CYLD (rat) RNRSELFYTLNGSSV Y353
S362-p
FyTLNGSsVDSQPQs
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • CAMK2A (human)
Putative in vivo kinases:
  • CAMK2A (human)
Treatment
  • ATP
  • autocamtide_inhibitory_peptide
  • Ca(2+)
  • KN-93
view more >
CYLD (human) FyTLNGSsVDSQPQs S362-p
CYLD (mouse) FYTLNGSSVDSQQSK S359
CYLD (rat) FYTLNGSSVDSQQQS S359
S369-p
sVDSQPQsKSkNTWy
0 1
CYLD (human) sVDSQPQsKSkNTWy S369-p
CYLD (mouse) SSVDSQQSKSKNPWY S365
CYLD (rat) SVDSQQQSKSKNPWY S366
K372-ub
SQPQsKSkNTWyIDE
0 2
CYLD (human) SQPQsKSkNTWyIDE K372-ub
CYLD (mouse) DSQQSKSKNPWYIDE K368
CYLD (rat) SQQQSKSKNPWYIDE K369
Y376-p
sKSkNTWyIDEVAED
0 1
CYLD (human) sKSkNTWyIDEVAED Y376-p
CYLD (mouse) SKSKNPWYIDEVAED Y372
CYLD (rat) SKSKNPWYIDEVAED Y373
S387-p
VAEDPAKsLtEIsTD
0 4
CYLD (human) VAEDPAKsLtEIsTD S387-p
CYLD (mouse) VAEDPAKSLTEMSSD S383
CYLD (rat) VAEDPAKSLTEMSSD S384
T389-p
EDPAKsLtEIsTDFD
0 1
CYLD (human) EDPAKsLtEIsTDFD T389-p
CYLD (mouse) EDPAKSLTEMSSDFG T385
CYLD (rat) EDPAKSLTEMSSDFG T386
S392-p
AKsLtEIsTDFDRSs
Upstream
0 1
Treatment
  • TNF
CYLD (human) AKsLtEIsTDFDRSs S392-p
CYLD (mouse) AKSLTEMSSDFGHSS S388
CYLD (rat) AKSLTEMSSDFGHSS S389
S399-p
sTDFDRSsPPLQPPP
0 3
CYLD (human) sTDFDRSsPPLQPPP S399-p
CYLD (mouse) SSDFGHSSPPPQPPS S395
CYLD (rat) SSDFGHSSPPPQPPS S396
S409-p
LQPPPVNsLTTENRF
0 1
CYLD (human) LQPPPVNsLTTENRF S409-p
CYLD (mouse) PQPPSMNSLSSENRF S405
CYLD (rat) PQPPSMNSLSSENRF S406
S418-p
TTENRFHsLPFsLtK
Upstream
Downstream
5 53
CYLD (human)
S418-p
Effects on Modified Protein
  • enzymatic activity, induced
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • CAMK2A (human)
  • IKKB (human)
Putative in vivo kinases:
  • CAMK2A (human)
  • IKKB (human)
Regulatory protein:
  • OTULINL (human)
Treatment
  • (5Z)-7-oxozeaenol
  • ATP
  • autocamtide_inhibitory_peptide
  • Ca(2+)
  • IKK_inhibitor_VII
  • IKKB inhibitor XII
  • ionomycin
  • ischemia
  • KN-93
  • muramyl_dipeptide
  • phorbol_ester
  • TNF
view more >
CYLD (human) TTENRFHsLPFsLtK S418-p
CYLD (mouse) SSENRFHsLPFsLtK S414-p
CYLD (rat) SSENRFHsLPFsLTK S415-p
S422-p
RFHsLPFsLtKMPNT
Upstream
Downstream
1 18
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) RFHsLPFsLtKMPNT S422-p
CYLD (mouse) RFHsLPFsLtKMPNT S418-p
CYLD (rat) RFHsLPFsLTKMPNT S419-p
T424-p
HsLPFsLtKMPNTNG
0 2
CYLD (human) HsLPFsLtKMPNTNG T424-p
CYLD (mouse) HsLPFsLtKMPNTNG T420-p
CYLD (rat) HsLPFsLTKMPNTNG T421
S432-p
KMPNTNGsIGHsPLs
Upstream
Downstream
1 0
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) KMPNTNGsIGHsPLs S432-p
CYLD (mouse) KMPNTNGSMAHSPLS S428
CYLD (rat) KMPNTNGSMAHSPLS S429
S436-p
TNGsIGHsPLsLsAQ
Upstream
Downstream
1 0
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) TNGsIGHsPLsLsAQ S436-p
CYLD (mouse) TNGSMAHSPLSLSVQ S432
CYLD (rat) TNGSMAHSPLSLSVQ S433
S439-p
sIGHsPLsLsAQsVM
Upstream
Downstream
2 1
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) sIGHsPLsLsAQsVM S439-p
CYLD (mouse) SMAHSPLSLSVQSVM S435
CYLD (rat) SMAHSPLSLSVQSVM S436
S441-p
GHsPLsLsAQsVMEE
Upstream
Downstream
1 0
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) GHsPLsLsAQsVMEE S441-p
CYLD (mouse) AHSPLSLSVQSVMGE S437
CYLD (rat) AHSPLSLSVQSVMGE S438
S444-p
PLsLsAQsVMEELNT
Upstream
Downstream
2 1
Effects on Modified Protein
  • ubiquitination
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • ionomycin
  • phorbol_ester
  • TNF
view more >
CYLD (human) PLsLsAQsVMEELNT S444-p
CYLD (mouse) PLSLSVQSVMGELNS S440
CYLD (rat) PLSLSVQSVMGELNS S441
Y523-p
GTFRGTRyFTCALKk
0 1
CYLD (human) GTFRGTRyFTCALKk Y523-p
CYLD (mouse) GTFRGTRYFTCALKk Y519
CYLD (rat) GTFRGTRYFTCALKK Y520
K530-ub
yFTCALKkALFVKLK
Downstream
1 2
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • signaling pathway regulation
CYLD (human) yFTCALKkALFVKLK K530-ub
CYLD (mouse) YFTCALKkALFVKLK K526-ub
CYLD (rat) YFTCALKKALFVKLK K527
S547-p
RPDSRFAsLQPVsNQ
0 4
CYLD (human) RPDSRFAsLQPVsNQ S547-p
CYLD (mouse) RPDSRFAsLQPVSNQ S543-p
CYLD (rat) RPDSRFASLQPVSNQ S544
S552-p
FAsLQPVsNQIERCN
0 1
CYLD (human) FAsLQPVsNQIERCN S552-p
CYLD (mouse) FAsLQPVSNQIERCN S548
CYLD (rat) FASLQPVSNQIERCN S549
S560-p
NQIERCNsLAFGGYL
0 2
CYLD (human) NQIERCNsLAFGGYL S560-p
CYLD (mouse) NQIERCNsLAFGGYL S556-p
CYLD (rat) NQIERCNSLAFGGYL S557
S568-p
LAFGGYLsEVVEENT
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • IKKB (human)
Treatment
  • TNF
CYLD (human) LAFGGYLsEVVEENT S568-p
CYLD (mouse) LAFGGYLSEVVEENT S564
CYLD (rat) LAFGGYLSEVVEENT S565
K627-ub
VLLRPKEkNDVEYYS
0 3
CYLD (human) VLLRPKEkNDVEYYS K627-ub
CYLD (mouse) VLLRPKEkNDIEYYS K623-ub
CYLD (rat) VLLRPKEKNDVEYYS K624
K668-ub
KLRKILEkVEAASGF
0 1
CYLD (human) KLRKILEkVEAASGF K668-ub
CYLD (mouse) KLRKILEKVEAASGF K664
CYLD (rat) KLRKILEKVEAASGF K665
K701-ub
LRVEPLLkIRSAGQK
0 1
CYLD (human) LRVEPLLkIRSAGQK K701-ub
CYLD (mouse) LRVEPLLKIRSAGQK K697
CYLD (rat) LRVEPLLKIRSAGQK K698
K721
FYQIFMEKNEKVGVP
0 1
CYLD (human) FYQIFMEKNEKVGVP K721
CYLD (mouse) FYQIFMEkNEKVGVP K717-ub
CYLD (rat) FYQIFMEKNEKVGVP K718
K768-ub
KDFKLFKkIFPsLEL
0 1
CYLD (human) KDFKLFKkIFPsLEL K768-ub
CYLD (mouse) KDFKLFKKIFPSLEL K764
CYLD (rat) KDFKLFKKIFPSLEL K765
S772-p
LFKkIFPsLELNITD
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • CAMK2A (human)
Putative in vivo kinases:
  • CAMK2A (human)
Treatment
  • ATP
  • autocamtide_inhibitory_peptide
  • Ca(2+)
  • KN-93
view more >
CYLD (human) LFKkIFPsLELNITD S772-p
CYLD (mouse) LFKKIFPSLELNITD S768
CYLD (rat) LFKKIFPSLELNITD S769
K818-ub
GKIKQFCkTCNTQVH
0 2
CYLD (human) GKIKQFCkTCNTQVH K818-ub
CYLD (mouse) GKIKQFCKTCSTQVH K814
CYLD (rat) GKIKQFCKTCSTQVH K815
K829-ub
TQVHLHPkRLNHkYN
0 1
CYLD (human) TQVHLHPkRLNHkYN K829-ub
CYLD (mouse) TQVHLHPRRLNHSYH R825
CYLD (rat) TQVHLHPRRLNHTYH R826
K834-ub
HPkRLNHkYNPVSLP
0 2
CYLD (human) HPkRLNHkYNPVSLP K834-ub
CYLD (mouse) HPRRLNHSYHPVSLP S830
CYLD (rat) HPRRLNHTYHPVSLP T831
K842-ub
YNPVSLPkDLPDWDW
0 1
CYLD (human) YNPVSLPkDLPDWDW K842-ub
CYLD (mouse) YHPVSLPKDLPDWDW K838
CYLD (rat) YHPVSLPKDLPDWDW K839