Other Species / Isoforms
  IKKA (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T23-p
EMRERLGtGGFGNVS
Upstream
7 4
Treatment
  • insulin
  • skin aging
  • UVB
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IKKA (human) EMRERLGtGGFGNVC T23-p
IKKA (mouse) EMRERLGtGGFGNVS T23-p
IKKA (rat) EMRERLGTGGFGNVS T23
K44
LDLKIAIKSCRLELS
0 2
IKKA (human) LDLKIAIkSCRLELS K44-ub
IKKA (mouse) LDLKIAIKSCRLELS K44
IKKA (rat) LDLKIAIKSCRLELS K44
K53
CRLELSSKNRERWCH
0 2
IKKA (human) CRLELSTkNRERWCH K53-ub
IKKA (mouse) CRLELSSKNRERWCH K53
IKKA (rat) CRLELSTKNRERWCH K53
K105
CSGGDLRKLLNKPEN
0 2
IKKA (human) CSGGDLRkLLNkPEN K105-ub
IKKA (mouse) CSGGDLRKLLNKPEN K105
IKKA (rat) CSGGDLRKLLNKPEN K105
K109
DLRKLLNKPENCCGL
0 2
IKKA (human) DLRkLLNkPENCCGL K109-ub
IKKA (mouse) DLRKLLNKPENCCGL K109
IKKA (rat) DLRKLLNKPENCCGL K109
K117
PENCCGLKESQILSL
0 1
IKKA (human) PENCCGLkEsQILSL K117-ub
IKKA (mouse) PENCCGLKESQILSL K117
IKKA (rat) PENCCGLKESQILSL K117
S119
NCCGLKESQILSLLS
1 0
IKKA (human) NCCGLkEsQILSLLS S119-ac
IKKA (mouse) NCCGLKESQILSLLS S119
IKKA (rat) NCCGLKESQILSLLS S119
K139
IRYLHENKIIHRDLK
0 2
IKKA (human) IRYLHENkIIHRDLk K139-ub
IKKA (mouse) IRYLHENKIIHRDLK K139
IKKA (rat) IRYLHENKIIHRDLK K139
K146
KIIHRDLKPENIVLQ
0 2
IKKA (human) kIIHRDLkPENIVLQ K146-ub
IKKA (mouse) KIIHRDLKPENIVLQ K146
IKKA (rat) KIIHRDLKPENIVLQ K146
K158
VLQDVGGKTIHKIID
0 2
IKKA (human) VLQDVGGkIIHKIID K158-ub
IKKA (mouse) VLQDVGGKTIHKIID K158
IKKA (rat) VLQDVGGKIMHKIID K158
S176-p
AKDVDQGsLCTsFVG
Upstream
Downstream
34 1
IKKA (human)
S176-p
IKKA (mouse)
S176-p
IKKA (rat)
S176-p
Effects on Biological Processes:
  • apoptosis, induced
  • cell differentiation, inhibited
  • transcription, altered
  • transcription, induced
Putative in vivo kinases:
  • IKKA (human)
Regulatory protein:
  • DDIT4 (human)
  • DOK3 (human)
  • FADD (human)
  • GRN (human)
  • GSK3B (human)
  • ILK (mouse)
  • IRS1 (rat)
  • PKM iso2 (human)
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Treatment
  • antibody
  • bacterial infection
  • bortezomib
  • high_glucose
  • leptin
  • LPS
  • Necrostatin-1
  • nitric_oxide
  • partial_hepatectomy
  • PD98059
  • TNF
  • VP3.15
  • wortmannin
  • Z-VAD-FMK
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IKKA (human) AKDVDQGsLCtsFVG S176-p
IKKA (mouse) AKDVDQGsLCTsFVG S176-p
IKKA (rat) AKDVDQGSLCTsFVG S176
T179
VDQGsLCTsFVGTLQ
1 0
IKKA (human) VDQGsLCtsFVGTLQ T179-ac
IKKA (mouse) VDQGsLCTsFVGTLQ T179
IKKA (rat) VDQGSLCTsFVGTLQ T179
S180-p
DQGsLCTsFVGTLQY
Upstream
Downstream
45 0
IKKA (human)
S180-p
IKKA (mouse)
S180-p
IKKA (rat)
S180-p
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, induced
  • cell differentiation, inhibited
  • cell growth, altered
  • transcription, altered
Regulatory protein:
  • BRAF (human)
  • DOK3 (human)
  • GRN (human)
  • ILK (mouse)
  • IRS1 (rat)
  • PKM iso2 (human)
  • SHP-2 (mouse)
  • TSC2 (mouse)
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Treatment
  • antibody
  • bacterial infection
  • bortezomib
  • cAMP_analog
  • cells
  • GDNF
  • IL-10
  • KT5720
  • leptin
  • linoleic_acid
  • LPS
  • MMS
  • NGF
  • nitric_oxide
  • NS398
  • PD98059
  • peptidoglycan
  • PGE2
  • siRNA
  • TNF
  • U0126
  • wortmannin
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IKKA (human) DQGsLCtsFVGTLQY S180-p
IKKA (mouse) DQGsLCTsFVGTLQY S180-p
IKKA (rat) DQGSLCTsFVGTLQY S180-p
K296
GPIDLTLKQPRCFAL
1 4
IKKA (human) GPVDLTLkQPRCFVL K296-ub
IKKA (mouse) GPIDLTLKQPRCFAL K296
IKKA (rat) GPIDPPLKQPKCFVL K296
K322
ILNMTSAKIISFLLP
0 1
IKKA (human) ILNMTSAkIISFLLP K322-ac
IKKA (mouse) ILNMTSAKIISFLLP K322
IKKA (rat) ILNMTSAKIISFLLP K322
K366
GISLDPRKPASQCVL
0 2
IKKA (human) GISLDPRkPASQCVL K366-ub
IKKA (mouse) GISLDPRKPASQCVL K366
IKKA (rat) GISLDPRKPASQCVL K366
K391
VYLFDKSKTVYEGPF
0 1
IKKA (human) VYLFDKSkTVYEGPF K391-ub
IKKA (mouse) VYLFDKSKTVYEGPF K391
IKKA (rat) VYLFDKSKTVYEGPF K391
K415
NYIVQDSKIQLPIIQ
0 1
IKKA (human) NYIVQDSkIQLPIIQ K415-ub
IKKA (mouse) NYIVQDSKIQLPIIQ K415
IKKA (rat) NYIVQDSKIQLPVTQ K415
K438
VHYVSGLKEDYSRLF
0 1
IKKA (human) VHYVSGLkEDYSRLF K438-ac
IKKA (mouse) VHYVSGLKEDYSRLF K438
IKKA (rat) VHYVSGLKEDYSRLF K438
T463
LRYNANLTKMKNTLI
0 2
IKKA (human) LRYNANLtKMKNTLI T463-p
IKKA (mouse) LRYNANLTKMKNTLI T463
IKKA (rat) LRYNANLTKMKNTLI T463
S473
KNTLISASQQLKAKL
1 0
IKKA (human) KNTLISAsQQLKAKL S473-p
IKKA (mouse) KNTLISASQQLKAKL S473
IKKA (rat) KNTLISASQQLKAKL S473
T499-p
ERYSEQMtYGISSEk
0 1
IKKA (human) ERYSEQMTyGISSEk T499
IKKA (mouse) ERYSEQMtYGISSEk T499-p
IKKA (rat) ERYSEQMTYGISSEK T499
Y500
RYSEQMtYGISSEkM
0 1
IKKA (human) RYSEQMTyGISSEkM Y500-p
IKKA (mouse) RYSEQMtYGISSEkM Y500
IKKA (rat) RYSEQMTYGISSEKM Y500
K506-ub
tYGISSEkMLKAWKE
0 2
IKKA (human) TyGISSEkMLKAWKE K506-ub
IKKA (mouse) tYGISSEkMLKAWKE K506-ub
IKKA (rat) TYGISSEKMLKAWKE K506
K569
QRAIDLYKQLKHRPP
0 1
IKKA (human) QRAIDLYkQLkHRPs K569-ub
IKKA (mouse) QRAIDLYKQLKHRPP K569
IKKA (rat) QRAIDLYKQLKHRPT K569
K572
IDLYKQLKHRPPDHL
0 1
IKKA (human) IDLYkQLkHRPsDHS K572-ub
IKKA (mouse) IDLYKQLKHRPPDHL K572
IKKA (rat) IDLYKQLKHRPTDHS K572
P576
KQLKHRPPDHLYSDS
0 1
IKKA (human) kQLkHRPsDHSYSDS S576-p
IKKA (mouse) KQLKHRPPDHLYSDS P576
IKKA (rat) KQLKHRPTDHSYSDS T576
T593
MVKIIVHTVQSQDRV
0 1
IKKA (human) MVKIIVHtVQSQDRV T593-p
IKKA (mouse) MVKIIVHTVQSQDRV T593
IKKA (rat) MVKIIVHTVQSQDRV T593
K602
QSQDRVLKELFGHLS
0 1
IKKA (human) QSQDRVLkELFGHLS K602-ub
IKKA (mouse) QSQDRVLKELFGHLS K602
IKKA (rat) QSQDRVLKELFGHLS K602
K615
LSKLLGCKQKIIDLL
0 1
IKKA (human) LSKLLGCkQkIIDLL K615-ub
IKKA (mouse) LSKLLGCKQKIIDLL K615
IKKA (rat) LSKLLGCKQKIIDLL K615
K617
KLLGCKQKIIDLLPK
0 1
IKKA (human) KLLGCkQkIIDLLPk K617-ub
IKKA (mouse) KLLGCKQKIIDLLPK K617
IKKA (rat) KLLGCKQKIIDLLPK K617
K624
KIIDLLPKVEVALSN
0 1
IKKA (human) kIIDLLPkVEVALSN K624-ub
IKKA (mouse) KIIDLLPKVEVALSN K624
IKKA (rat) KIIDLLPKVEVALSN K624
T722
NCLGHLSTIIREANE
1 0
IKKA (human) NCLGHLStIIHEANE T722-ac
IKKA (mouse) NCLGHLSTIIREANE T722
IKKA (rat) gap -