Other Species / Isoforms
  PLK1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
N2
______MNAAAKAGK
0 3
PLK1 (human) ______MsAAVtAGK S2
PLK1 (mouse) ______MNAAAKAGK N2
PLK1 (rat) ______MNAAAKAGK N2
PLK1 (frog) gap -
K6
__MNAAAKAGKLARA
0 3
PLK1 (human) __MsAAVtAGKLARA T6
PLK1 (mouse) __MNAAAKAGKLARA K6
PLK1 (rat) __MNAAAKAGKLARA K6
PLK1 (frog) ___MAQVAGKKLTVA A5
A34
VPGAPVAAPLAKEIP
1 1
PLK1 (human) APGAPAAAPPAKEIP A34
PLK1 (mouse) VPGAPVAAPLAKEIP A34
PLK1 (rat) APGAPGAAPLAKEIP A34
PLK1 (frog) PPGIPGSssAVKEIP S25
P35
PGAPVAAPLAKEIPE
1 1
PLK1 (human) PGAPAAAPPAKEIPE P35
PLK1 (mouse) PGAPVAAPLAKEIPE P35
PLK1 (rat) PGAPGAAPLAKEIPE P35
PLK1 (frog) PGIPGSssAVKEIPE S26
S49
EVLVDPRSRRQYVRG
1 0
PLK1 (human) EVLVDPRsRRRYVRG S49
PLK1 (mouse) EVLVDPRSRRQYVRG S49
PLK1 (rat) EVLMDPRSRRQYVRG S49
PLK1 (frog) EILVDPRTRRRYLRG T40
S99
PHQKEKMSMEISIHR
1 0
PLK1 (human) PHQREKMsMEIsIHR S99
PLK1 (mouse) PHQKEKMSMEISIHR S99
PLK1 (rat) PHQKEKMSMEISIHR S99
PLK1 (frog) PHQKDKMTMEIAIQR T90
S103
EKMSMEISIHRSLAH
0 1
PLK1 (human) EKMsMEIsIHRSLAH S103
PLK1 (mouse) EKMSMEISIHRSLAH S103
PLK1 (rat) EKMSMEISIHRSLAH S103
PLK1 (frog) DKMTMEIAIQRSLDH A94
S137
LELCRRRSLLELHKR
7 3
PLK1 (human) LELCRRRsLLELHKR S137
PLK1 (mouse) LELCRRRSLLELHKR S137
PLK1 (rat) LELCRRRSLLELHKR S137
PLK1 (frog) LELCRRRSLLELHKR S128
Y166
QIVLGCQyLHRNQVI
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • Src (human)
PLK1 (human) QIVLGCQYLHRNRVI Y166
PLK1 (mouse) QIVLGCQyLHRNQVI Y166
PLK1 (rat) QIVLGCQYLHRNQVI Y166
PLK1 (frog) QTISGCQYLHSNRVI Y157
T210
YEGERKKtLCGtPNY
Upstream
Downstream
59 74
PLK1 (human)
T210
PLK1 (mouse)
T210
PLK1 (rat)
T210
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • AurA (mouse)
Regulatory protein:
  • SHP-2 (human)
Treatment
  • BI_4834
  • hesperadin
  • MG132
  • nocodazole
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PLK1 (human) YDGERKKtLCGtPNy T210
PLK1 (mouse) YEGERKKtLCGtPNY T210
PLK1 (rat) YEGERKKtLCGTPNY T210
PLK1 (frog) YDGERKKTLCGTPNY T201
T214
RKKtLCGtPNYIAPE
1 22
PLK1 (human) RKKtLCGtPNyIAPE T214
PLK1 (mouse) RKKtLCGtPNYIAPE T214
PLK1 (rat) RKKtLCGTPNYIAPE T214
PLK1 (frog) RKKTLCGTPNYIAPE T205
Y217
tLCGtPNYIAPEVLS
1 150
PLK1 (human) tLCGtPNyIAPEVLs Y217
PLK1 (mouse) tLCGtPNYIAPEVLS Y217
PLK1 (rat) tLCGTPNYIAPEVLS Y217
PLK1 (frog) TLCGTPNYIAPEVLG Y208
S224
YIAPEVLSKKGHSFE
0 4
PLK1 (human) yIAPEVLsKKGHSFE S224
PLK1 (mouse) YIAPEVLSKKGHSFE S224
PLK1 (rat) YIAPEVLSKKGHSFE S224
PLK1 (frog) YIAPEVLGKKGHSFE G215
Y309
DEFFTSGYIPARLPI
0 1
PLK1 (human) DEFFTSGyIPARLPI Y309
PLK1 (mouse) DEFFTSGYIPARLPI Y309
PLK1 (rat) DEFFTSGYIPARLPI Y309
PLK1 (frog) DEFFTSGYIPSRLPT Y300
S326
LTIPPRFSIAPSSLD
1 2
PLK1 (human) LTIPPRFsIAPssLD S326
PLK1 (mouse) LTIPPRFSIAPSSLD S326
PLK1 (rat) LTIPPRFSIAPSSLD S326
PLK1 (frog) LTVPPRFSIAPSTID S317
S330
PRFSIAPSSLDPSSR
2 0
PLK1 (human) PRFsIAPssLDPsNR S330
PLK1 (mouse) PRFSIAPSSLDPSSR S330
PLK1 (rat) PRFSIAPSSLDPSNR S330
PLK1 (frog) PRFSIAPSTIDQsLR S321
S331
RFSIAPSSLDPSSRK
Upstream
0 3
Treatment
  • BI_4834
  • nocodazole
PLK1 (human) RFsIAPssLDPsNRK S331
PLK1 (mouse) RFSIAPSSLDPSSRK S331
PLK1 (rat) RFSIAPSSLDPSNRK S331
PLK1 (frog) RFSIAPSTIDQsLRK T322
S335
APSSLDPSSRKPLKV
1 2
PLK1 (human) APssLDPsNRKPLtV S335
PLK1 (mouse) APSSLDPSSRKPLKV S335
PLK1 (rat) APSSLDPSNRKPLTV S335
PLK1 (frog) APSTIDQsLRKPLTA S326
K341
PSSRKPLKVLNKGVE
0 2
PLK1 (human) PsNRKPLtVLNKGLE T341
PLK1 (mouse) PSSRKPLKVLNKGVE K341
PLK1 (rat) PSNRKPLTVLNKGVE T341
PLK1 (frog) QsLRKPLTAINKGQD T332
N349
VLNKGVENPLPDRPR
1 1
PLK1 (human) VLNKGLENPLPERPR N349
PLK1 (mouse) VLNKGVENPLPDRPR N349
PLK1 (rat) VLNKGVENPLPDRPR N349
PLK1 (frog) AINKGQDsPLVEKQV S340
T366
EEPVVRETNEAIECH
0 1
PLK1 (human) EEPVVREtGEVVDCH T366
PLK1 (mouse) EEPVVRETNEAIECH T366
PLK1 (rat) EEPVVRETNEAIECH T366
PLK1 (frog) EEMQQPEFTEPADCY F360
S375
EAIECHLSDLLQQLT
0 3
PLK1 (human) EVVDCHLsDMLQQLH S375
PLK1 (mouse) EAIECHLSDLLQQLT S375
PLK1 (rat) EAIECHLSDLLQQLT S375
PLK1 (frog) EPADCYLSEMLQQLT S369
S383
DLLQQLTSVNASKPS
1 2
PLK1 (human) DMLQQLHsVNAsKPS S383
PLK1 (mouse) DLLQQLTSVNASKPS S383
PLK1 (rat) DLLQQLTSVNASKPS S383
PLK1 (frog) EMLQQLTCLNAVKPS C377
S387
QLTSVNASKPSERGL
0 1
PLK1 (human) QLHsVNAsKPSERGL S387
PLK1 (mouse) QLTSVNASKPSERGL S387
PLK1 (rat) QLTSVNASKPSERGL S387
PLK1 (frog) QLTCLNAVKPSERAL V381
Y425
SDKYGLGYQLCDNSV
1 1
PLK1 (human) SDKYGLGyQLCDNSV Y425
PLK1 (mouse) SDKYGLGYQLCDNSV Y425
PLK1 (rat) SDKYGLGYQLCDNSV Y425
PLK1 (frog) SDKYGLGYQLCDNSV Y419
Y445
DSTRLILyNDGDSLQ
Upstream
Downstream
3 1
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • Src (human)
PLK1 (human) DSTRLILyNDGDsLQ Y445
PLK1 (mouse) DSTRLILyNDGDSLQ Y445
PLK1 (rat) DSTRLILYNDGDSLQ Y445
PLK1 (frog) DSTRLIMYNDGDSLQ Y439
S450
ILyNDGDSLQYIERD
0 3
PLK1 (human) ILyNDGDsLQYIERD S450
PLK1 (mouse) ILyNDGDSLQYIERD S450
PLK1 (rat) ILYNDGDSLQYIERD S450
PLK1 (frog) IMYNDGDSLQYIERN S444
T459
QYIERDGTESYLTVS
0 1
PLK1 (human) QYIERDGtEsyLtVs T459
PLK1 (mouse) QYIERDGTESYLTVS T459
PLK1 (rat) QYIERDGTESYLTVS T459
PLK1 (frog) QYIERNNTESYLNVR T453
S461
IERDGTESYLTVSSH
0 2
PLK1 (human) IERDGtEsyLtVsSH S461
PLK1 (mouse) IERDGTESYLTVSSH S461
PLK1 (rat) IERDGTESYLTVSSH S461
PLK1 (frog) IERNNTESYLNVRSY S455
Y462
ERDGTESYLTVSSHP
0 1
PLK1 (human) ERDGtEsyLtVsSHP Y462
PLK1 (mouse) ERDGTESYLTVSSHP Y462
PLK1 (rat) ERDGTESYLTVSSHP Y462
PLK1 (frog) ERNNTESYLNVRSYP Y456
T464
DGTESYLTVSSHPNS
0 1
PLK1 (human) DGtEsyLtVsSHPNS T464
PLK1 (mouse) DGTESYLTVSSHPNS T464
PLK1 (rat) DGTESYLTVSSHPNS T464
PLK1 (frog) NNTESYLNVRSYPTT N458
S466
TESYLTVSSHPNSLM
0 1
PLK1 (human) tEsyLtVsSHPNSLM S466
PLK1 (mouse) TESYLTVSSHPNSLM S466
PLK1 (rat) TESYLTVSSHPNSLM S466
PLK1 (frog) TESYLNVRSYPTTLT R460
T498
LKAGANITPREGDEL
0 8
PLK1 (human) LKAGANItPREGDEL T498
PLK1 (mouse) LKAGANITPREGDEL T498
PLK1 (rat) LKAGANITPREGDEL T498
PLK1 (frog) LKAGANTTPREGDEL T492
S526
SAIILHLSNGTVQIN
1 0
PLK1 (human) SAIILHLsNGsVQIN S526
PLK1 (mouse) SAIILHLSNGTVQIN S526
PLK1 (rat) SAIILHLSNGTVQIN S526
PLK1 (frog) SAIILHLSNGTVQIN S520
T529
ILHLSNGTVQINFFQ
1 0
PLK1 (human) ILHLsNGsVQINFFQ S529
PLK1 (mouse) ILHLSNGTVQINFFQ T529
PLK1 (rat) ILHLSNGTVQINFFQ T529
PLK1 (frog) ILHLSNGTVQINFFQ T523
T539
INFFQDHTKLILCPL
1 0
PLK1 (human) INFFQDHtKLILCPL T539
PLK1 (mouse) INFFQDHTKLILCPL T539
PLK1 (rat) INFFQDHTKLILCPL T539
PLK1 (frog) INFFQDHTKIILCPL T533
S565
DFQTYRLSLLEEYGC
0 1
PLK1 (human) DFRTYRLsLLEEYGC S565
PLK1 (mouse) DFQTYRLSLLEEYGC S565
PLK1 (rat) DFRTYRLSLLEEYGC S565
PLK1 (frog) EFRTYKLSLIQEFGC S559
S578
GCCKELASRLRYART
0 1
PLK1 (human) GCCKELAsRLRYART S578
PLK1 (mouse) GCCKELASRLRYART S578
PLK1 (rat) GCCKELASRLRYART S578
PLK1 (frog) GCCKELASRLRYART S572
S597
LLSSRSASNRLKAS_
2 0
PLK1 (human) LLSSRSAsNRLKAS_ S597
PLK1 (mouse) LLSSRSASNRLKAS_ S597
PLK1 (rat) LLSSRSACNRLKAS_ C597
PLK1 (frog) LQSSKSAVAHVKASA V591