Other Species / Isoforms
  GAB1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y47
GDPDVLEYYKNDHAK
0 2
GAB1 (human) GDPDVLEyyKNDHAK Y47-p
GAB1 iso2 (human) GDPDVLEYYKNDHAK Y47
GAB1 (mouse) GDPDVLEYYKNDHAK Y47
GAB1 (rat) GDPDVLEYYKNDHAK Y47
Y48
DPDVLEYYKNDHAKK
1 1
GAB1 (human) DPDVLEyyKNDHAKK Y48-p
GAB1 iso2 (human) DPDVLEYYKNDHAKK Y48
GAB1 (mouse) DPDVLEYYKNDHAKK Y48
GAB1 (rat) DPDVLEYYKNDHAKK Y48
Y83-p
KKEFENSyIFDINTI
Upstream
2 0
Regulatory protein:
  • PTP1B (human)
GAB1 (human) KKEFENSyIFDINTI Y83-p
GAB1 iso2 (human) KKEFENSYIFDINTI Y83
GAB1 (mouse) KKEFENSyIFDINTI Y83-p
GAB1 (rat) KKEFENSYIFDINTI Y83
Y183
LQDDPQDYLLLINCQ
0 29
GAB1 (human) IQEDPQDyLLLINCQ Y183-p
GAB1 iso2 (human) IQEDPQDYLLLINCQ Y183
GAB1 (mouse) LQDDPQDYLLLINCQ Y183
GAB1 (rat) LREDPQDyLLLINCQ Y183-p
K205-ub
RTLFDSAkPTFSETD
0 4
GAB1 (human) RTHADSAkSTSSETD K205-ub
GAB1 iso2 (human) RTHADSAKSTSSETD K205
GAB1 (mouse) RTLFDSAkPTFSETD K205-ub
GAB1 (rat) RAHFDSAKPTSSETD K205
Q221
NDNVPSHQTPASSQS
0 4
GAB1 (human) NDNVPSHkNPASSQS K221-ub
GAB1 iso2 (human) NDNVPSHKNPASSQS K221
GAB1 (mouse) NDNVPSHQTPASSQS Q221
GAB1 (rat) NDNVPSHKPPASSQG K221
Y242-p
FFQQQMMyDCPPSRL
2 275
GAB1 (human) FFQQQMIyDsPPSRA Y242-p
GAB1 iso2 (human) FFQQQMIyDSPPSRA Y242-p
GAB1 (mouse) FFQQQMMyDCPPSRL Y242-p
GAB1 (rat) GFFQQMVYDCPPPRV Y241
C244
QQQMMyDCPPSRLts
0 3
GAB1 (human) QQQMIyDsPPSRAPs S244-p
GAB1 iso2 (human) QQQMIyDSPPSRAPS S244
GAB1 (mouse) QQQMMyDCPPSRLts C244
GAB1 (rat) FQQMVYDCPPPRVTs C243
T250-p
DCPPSRLtsVsGESS
0 1
GAB1 (human) DsPPSRAPsAsVDss P250
GAB1 iso2 (human) DSPPSRAPSASVDSS P250
GAB1 (mouse) DCPPSRLtsVsGESS T250-p
GAB1 (rat) DCPPPRVTsVSGEsG T249
S251-p
CPPSRLtsVsGESSL
0 6
GAB1 (human) sPPSRAPsAsVDssL S251-p
GAB1 iso2 (human) SPPSRAPSASVDSSL S251
GAB1 (mouse) CPPSRLtsVsGESSL S251-p
GAB1 (rat) CPPPRVTsVSGEsGL S250-p
S253-p
PSRLtsVsGESSLyN
0 5
GAB1 (human) PSRAPsAsVDssLyN S253-p
GAB1 iso2 (human) PSRAPSASVDSSLyN S253
GAB1 (mouse) PSRLtsVsGESSLyN S253-p
GAB1 (rat) PPRVTsVSGEsGLyN S252
S256
LtsVsGESSLyNLPR
0 2
GAB1 (human) APsAsVDssLyNLPR S256-p
GAB1 iso2 (human) APSASVDSSLyNLPR S256
GAB1 (mouse) LtsVsGESSLyNLPR S256
GAB1 (rat) VTsVSGEsGLyNLPR S255-p
S257
tsVsGESSLyNLPRS
0 6
GAB1 (human) PsAsVDssLyNLPRS S257-p
GAB1 iso2 (human) PSASVDSSLyNLPRS S257
GAB1 (mouse) tsVsGESSLyNLPRS S257
GAB1 (rat) TsVSGEsGLyNLPRS G256
Y259-p
VsGESSLyNLPRSYs
Upstream
2 514
Regulatory protein:
  • Pyk2 (mouse)
Treatment
  • EGF
  • insulin
  • PF-4594755
GAB1 (human) AsVDssLyNLPRSys Y259-p
GAB1 iso2 (human) ASVDSSLyNLPRSYS Y259-p
GAB1 (mouse) VsGESSLyNLPRSYs Y259-p
GAB1 (rat) VSGEsGLyNLPRSYs Y258-p
Y265
LyNLPRSYsHDVLPK
0 1
GAB1 (human) LyNLPRSysHDVLPK Y265-p
GAB1 iso2 (human) LyNLPRSYSHDVLPK Y265
GAB1 (mouse) LyNLPRSYsHDVLPK Y265
GAB1 (rat) LyNLPRSYsHDVLPK Y264
S266-p
yNLPRSYsHDVLPKE
Upstream
0 43
Treatment
  • insulin
  • LPS
GAB1 (human) yNLPRSysHDVLPKV S266-p
GAB1 iso2 (human) yNLPRSYSHDVLPKV S266
GAB1 (mouse) yNLPRSYsHDVLPKE S266-p
GAB1 (rat) yNLPRSYsHDVLPKE S265-p
S274
HDVLPKESPSSTEAD
0 1
GAB1 (human) HDVLPKVsPSSTEAD S274-p
GAB1 iso2 (human) HDVLPKVSPSSTEAD S274
GAB1 (mouse) HDVLPKESPSSTEAD S274
GAB1 (rat) HDVLPKESPSSTEAD S273
Y285-p
TEADGELyTFNTPSG
Upstream
4 17
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
Treatment
  • EGF
  • PDGF
GAB1 (human) TEADGELyVFNTPSG Y285-p
GAB1 iso2 (human) TEADGELYVFNTPSG Y285
GAB1 (mouse) TEADGELyTFNTPSG Y285-p
GAB1 (rat) TEADGELYVFNTPSG Y284
S304-p
ETQMRHVsISyDIPP
Upstream
0 5
Treatment
  • insulin
GAB1 (human) ETQMRHVsIsyDIPP S304-p
GAB1 iso2 (human) ETQMRHVSISYDIPP S304
GAB1 (mouse) ETQMRHVsISyDIPP S304-p
GAB1 (rat) EAQMRHVSISYDIPP S303
S306
QMRHVsISyDIPPtP
0 8
GAB1 (human) QMRHVsIsyDIPPtP S306-p
GAB1 iso2 (human) QMRHVSISYDIPPTP S306
GAB1 (mouse) QMRHVsISyDIPPtP S306
GAB1 (rat) QMRHVSISYDIPPTP S305
Y307-p
MRHVsISyDIPPtPG
Upstream
Downstream
7 41
GAB1 (human)
Y307-p
GAB1 (mouse)
Y307-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell differentiation, altered
  • cell growth, altered
  • cell motility, induced
  • signaling pathway regulation
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • CXCL12 (human)
  • CXCL13 (human)
Treatment
  • conditioned medium
  • EGF
  • HGF
  • ibrutinib
  • plerixafor
GAB1 (human) MRHVsIsyDIPPtPG Y307-p
GAB1 iso2 (human) MRHVSISYDIPPTPG Y307
GAB1 (mouse) MRHVsISyDIPPtPG Y307-p
GAB1 (rat) MRHVSISYDIPPTPG Y306
T312-p
ISyDIPPtPGNtyQI
Upstream
0 4
Treatment
  • insulin
GAB1 (human) IsyDIPPtPGNtyQI T312-p
GAB1 iso2 (human) ISYDIPPTPGNTyQI T312
GAB1 (mouse) ISyDIPPtPGNtyQI T312-p
GAB1 (rat) ISYDIPPTPGNTYQV T311
T316-p
IPPtPGNtyQIPRtF
0 47
GAB1 (human) IPPtPGNtyQIPRTF T316-p
GAB1 iso2 (human) IPPTPGNTyQIPRTF T316
GAB1 (mouse) IPPtPGNtyQIPRtF T316-p
GAB1 (rat) IPPTPGNTYQVPRTF T315
Y317-p
PPtPGNtyQIPRtFP
2 186
GAB1 (human) PPtPGNtyQIPRTFP Y317-p
GAB1 iso2 (human) PPTPGNTyQIPRTFP Y317-p
GAB1 (mouse) PPtPGNtyQIPRtFP Y317-p
GAB1 (rat) PPTPGNTYQVPRTFP Y316
T322-gl
NtyQIPRtFPESTLG
0 1
GAB1 (human) NtyQIPRTFPEGTLG T322
GAB1 iso2 (human) NTyQIPRTFPEGTLG T322
GAB1 (mouse) NtyQIPRtFPESTLG T322-gl
GAB1 (rat) NTYQVPRTFPEGTLG T321
S355-p
PHPTHDRsPVETCGV
0 6
GAB1 (human) PHPAHDRsPVETCSI S355-p
GAB1 iso2 (human) PHPAHDRSPVETCSI S355
GAB1 (mouse) PHPTHDRsPVETCGV S355-p
GAB1 (rat) PHSTHDRSPVEtCGV S354
T359
HDRsPVETCGVPRTA
0 1
GAB1 (human) HDRsPVETCSIPRtA T359
GAB1 iso2 (human) HDRSPVETCSIPRTA T359
GAB1 (mouse) HDRsPVETCGVPRTA T359
GAB1 (rat) HDRSPVEtCGVPRTA T358-p
T365
ETCGVPRTASDtDSS
0 3
GAB1 (human) ETCSIPRtAsDtDss T365-p
GAB1 iso2 (human) ETCSIPRTASDTDSS T365
GAB1 (mouse) ETCGVPRTASDtDSS T365
GAB1 (rat) EtCGVPRTASDTDSS T364
S367
CGVPRTASDtDSSyC
0 2
GAB1 (human) CSIPRtAsDtDssyC S367-p
GAB1 iso2 (human) CSIPRTASDTDSSyC S367
GAB1 (mouse) CGVPRTASDtDSSyC S367
GAB1 (rat) CGVPRTASDTDSSYC S366
T369-p
VPRTASDtDSSyCIP
0 3
GAB1 (human) IPRtAsDtDssyCIP T369-p
GAB1 iso2 (human) IPRTASDTDSSyCIP T369
GAB1 (mouse) VPRTASDtDSSyCIP T369-p
GAB1 (rat) VPRTASDTDSSYCIP T368
S371
RTASDtDSSyCIPPP
0 5
GAB1 (human) RtAsDtDssyCIPTA S371-p
GAB1 iso2 (human) RTASDTDSSyCIPTA S371
GAB1 (mouse) RTASDtDSSyCIPPP S371
GAB1 (rat) RTASDTDSSYCIPPA S370
S372
TASDtDSSyCIPPPA
0 1
GAB1 (human) tAsDtDssyCIPTAG S372-p
GAB1 iso2 (human) TASDTDSSyCIPTAG S372
GAB1 (mouse) TASDtDSSyCIPPPA S372
GAB1 (rat) TASDTDSSYCIPPAG S371
Y373-p
ASDtDSSyCIPPPAG
Upstream
Downstream
6 292
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, altered
  • cell growth, altered
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
Treatment
  • EGF
  • HGF
GAB1 (human) AsDtDssyCIPTAGM Y373-p
GAB1 iso2 (human) ASDTDSSyCIPTAGM Y373-p
GAB1 (mouse) ASDtDSSyCIPPPAG Y373-p
GAB1 (rat) ASDTDSSYCIPPAGM Y372
T382
IPPPAGMTPSRSNtI
0 9
GAB1 (human) CIPTAGMsPsRSNtI S381-p
GAB1 iso2 (human) CIPTAGMSPSRSNTI S381
GAB1 (mouse) IPPPAGMTPSRSNtI T382
GAB1 (rat) CIPPAGMPPSRSNtI P380
S384
PPAGMTPSRSNtIST
0 1
GAB1 (human) PTAGMsPsRSNtIsT S383-p
GAB1 iso2 (human) PTAGMSPSRSNTIST S383
GAB1 (mouse) PPAGMTPSRSNtIST S384
GAB1 (rat) PPAGMPPSRSNtIST S382
T388-p
MTPSRSNtISTVDLN
Upstream
1 6
Treatment
  • insulin
  • LY294002
GAB1 (human) MsPsRSNtIsTVDLN T387-p
GAB1 iso2 (human) MSPSRSNTISTVDLN T387
GAB1 (mouse) MTPSRSNtISTVDLN T388-p
GAB1 (rat) MPPSRSNtISTVDLN T386-p
S390
PSRSNtISTVDLNKL
0 2
GAB1 (human) PsRSNtIsTVDLNKL S389-p
GAB1 iso2 (human) PSRSNTISTVDLNKL S389
GAB1 (mouse) PSRSNtISTVDLNKL S390
GAB1 (rat) PSRSNtISTVDLNKL S388
S402
NKLRKDASsQDCyDI
0 4
GAB1 (human) NKLRKDAssQDCyDI S401-p
GAB1 iso2 (human) NKLRKDASSQDCyDI S401
GAB1 (mouse) NKLRKDASsQDCyDI S402
GAB1 (rat) NKLRKDAGSQDCyDI G400
S403-p
KLRKDASsQDCyDIP
Upstream
0 11
Treatment
  • insulin
GAB1 (human) KLRKDAssQDCyDIP S402-p
GAB1 iso2 (human) KLRKDASSQDCyDIP S402
GAB1 (mouse) KLRKDASsQDCyDIP S403-p
GAB1 (rat) KLRKDAGSQDCyDIP S401
Y407-p
DASsQDCyDIPRtFP
Upstream
Downstream
4 1116
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, altered
  • cell growth, altered
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
  • Src iso1 (mouse)
Treatment
  • EGF
  • HGF
GAB1 (human) DAssQDCyDIPRAFP Y406-p
GAB1 iso2 (human) DASSQDCyDIPRAFP Y406-p
GAB1 (mouse) DASsQDCyDIPRtFP Y407-p
GAB1 (rat) DAGSQDCyDIPRTFP Y405-p
T412-p
DCyDIPRtFPSDRss
Upstream
0 1
Treatment
  • insulin
GAB1 (human) DCyDIPRAFPSDRss A411
GAB1 iso2 (human) DCyDIPRAFPSDRSS A411
GAB1 (mouse) DCyDIPRtFPSDRss T412-p
GAB1 (rat) DCyDIPRTFPSDRSS T410
S418-p
RtFPSDRsssLEGFH
0 2
GAB1 (human) RAFPSDRsssLEGFH S417-p
GAB1 iso2 (human) RAFPSDRSSSLEGFH S417
GAB1 (mouse) RtFPSDRsssLEGFH S418-p
GAB1 (rat) RTFPSDRSSsLEGFH S416
S419-p
tFPSDRsssLEGFHS
0 3
GAB1 (human) AFPSDRsssLEGFHN S418-p
GAB1 iso2 (human) AFPSDRSSSLEGFHN S418
GAB1 (mouse) tFPSDRsssLEGFHS S419-p
GAB1 (rat) TFPSDRSSsLEGFHN S417
S420-p
FPSDRsssLEGFHSQ
Upstream
0 18
Regulatory protein:
  • ADRB1 (mouse)
Treatment
  • insulin
  • LY294002
GAB1 (human) FPSDRsssLEGFHNH S419-p
GAB1 iso2 (human) FPSDRSSSLEGFHNH S419
GAB1 (mouse) FPSDRsssLEGFHSQ S420-p
GAB1 (rat) FPSDRSSsLEGFHNQ S418-p
Y428-p
LEGFHSQyKIKSVLT
0 2
GAB1 (human) LEGFHNHFKVKNVLT F427
GAB1 iso2 (human) LEGFHNHFKVKNVLT F427
GAB1 (mouse) LEGFHSQyKIKSVLT Y428-p
GAB1 (rat) LEGFHNQLKIKNVLA L426
S440-p
VLTAGGVsGEELDEN
Upstream
0 3
Treatment
  • insulin
GAB1 (human) VLTVGSVSSEELDEN S439
GAB1 iso2 (human) VLTVGSVSSEELDEN S439
GAB1 (mouse) VLTAGGVsGEELDEN S440-p
GAB1 (rat) VLAAGNVSGEELDEN S438
Y448-p
GEELDENyVPMNPNs
Upstream
6 13
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
Treatment
  • H2O2
GAB1 (human) SEELDENyVPMNPNs Y447-p
GAB1 iso2 (human) SEELDENYVPMNPNS Y447
GAB1 (mouse) GEELDENyVPMNPNs Y448-p
GAB1 (rat) GEELDENYVPMNPNs Y446
S455-p
yVPMNPNsPPRQHSG
0 13
GAB1 (human) yVPMNPNsPPRQHSS S454-p
GAB1 iso2 (human) YVPMNPNSPPRQHSS S454
GAB1 (mouse) yVPMNPNsPPRQHSG S455-p
GAB1 (rat) YVPMNPNsPPRHHPS S453-p
Y473-p
EPIQEPNyVPMtPGT
Upstream
7 2
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
Treatment
  • H2O2
GAB1 (human) EPIQEANyVPMtPGT Y472-p
GAB1 iso2 (human) EPIQEANYVPMTPGT Y472
GAB1 (mouse) EPIQEPNyVPMtPGT Y473-p
GAB1 (rat) EPIQEPNYVPMTPGT Y471
T477-p
EPNyVPMtPGTFDFS
2 0
GAB1 (human) EANyVPMtPGTFDFS T476-p
GAB1 iso2 (human) EANYVPMTPGTFDFS T476
GAB1 (mouse) EPNyVPMtPGTFDFS T477-p
GAB1 (rat) EPNYVPMTPGTFDFS T475
S500-p
PAHMGFRssPKtPPR
0 1
GAB1 (human) PAHMGFRSsPKtPPR S499
GAB1 iso2 (human) PAHMGFRSSPKTPPR S499
GAB1 (mouse) PAHMGFRssPKtPPR S500-p
GAB1 (rat) PAHLGFRSSPKTPPR S498
S501-p
AHMGFRssPKtPPRR
0 3
GAB1 (human) AHMGFRSsPKtPPRR S500-p
GAB1 iso2 (human) AHMGFRSSPKTPPRR S500
GAB1 (mouse) AHMGFRssPKtPPRR S501-p
GAB1 (rat) AHLGFRSSPKTPPRR S499
T504-p
GFRssPKtPPRRPVP
Upstream
0 10
Treatment
  • insulin
  • MK-2206
GAB1 (human) GFRSsPKtPPRRPVP T503-p
GAB1 iso2 (human) GFRSSPKTPPRRPVP T503
GAB1 (mouse) GFRssPKtPPRRPVP T504-p
GAB1 (rat) GFRSSPKTPPRRPVP T502
-
gap
0 7
GAB1 (human) gap -
GAB1 iso2 (human) HGLERTDsQtIGDFA S547-p
GAB1 (mouse) gap -
GAB1 (rat) gap -
-
gap
0 1
GAB1 (human) gap -
GAB1 iso2 (human) LERTDsQtIGDFATR T549-p
GAB1 (mouse) gap -
GAB1 (rat) gap -
S552-p
ELQAPVRsPITRSFA
Upstream
Downstream
4 9
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Putative in vivo kinases:
  • ERK1 (human)
Treatment
  • Epo
  • insulin
  • U0126
GAB1 (human) ELQAPVRsPITRSFA S551-p
GAB1 iso2 (human) ELQAPVRSPITRSFA S581
GAB1 (mouse) ELQAPVRsPITRSFA S552-p
GAB1 (rat) ELQAPVRsPITRSFA S550-p
S568-p
DSSRFPMsPRPDSVH
1 0
GAB1 (human) DSSRFPMSPRPDSVH S567
GAB1 iso2 (human) DSSRFPMSPRPDSVH S597
GAB1 (mouse) DSSRFPMsPRPDSVH S568-p
GAB1 (rat) DSSRFPMSPRPDSVH S566
Y590-p
SHDSEENyVPMNPNL
Upstream
8 0
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
Treatment
  • H2O2
GAB1 (human) SHDSEENyVPMNPNL Y589-p
GAB1 iso2 (human) SHDSEENYVPMNPNL Y619
GAB1 (mouse) SHDSEENyVPMNPNL Y590-p
GAB1 (rat) SHDSEENYVPMNPNL Y588
Y628-p
KGDKQVEyLDLDLDs
Upstream
Downstream
24 460
GAB1 (human)
Y627-p
GAB1 (mouse)
Y628-p
GAB1 (rat)
Y626-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell motility, induced
  • signaling pathway regulation
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Putative upstream phosphatases:
  • PTP1B (human)
Regulatory protein:
  • Akt1 (human)
  • CXCL12 (human)
  • CXCL13 (human)
  • Pyk2 (mouse)
Treatment
  • conditioned medium
  • EGF
  • Epo
  • H2O2
  • insulin
  • LY294002
  • PF-4594755
  • plerixafor
  • PTP1B_inhibitor
  • U0126
GAB1 (human) KGDKQVEyLDLDLDs Y627-p
GAB1 iso2 (human) KGDKQVEyLDLDLDS Y657-p
GAB1 (mouse) KGDKQVEyLDLDLDs Y628-p
GAB1 (rat) KGDKQVEyLDLDLES Y626-p
S635-p
yLDLDLDsGKStPPR
0 3
GAB1 (human) yLDLDLDsGKstPPR S634-p
GAB1 iso2 (human) yLDLDLDSGKSTPPR S664
GAB1 (mouse) yLDLDLDsGKStPPR S635-p
GAB1 (rat) yLDLDLESGkSTPPR S633
K637
DLDLDsGKStPPRKQ
0 5
GAB1 (human) DLDLDsGKstPPRKQ K636
GAB1 iso2 (human) DLDLDSGKSTPPRKQ K666
GAB1 (mouse) DLDLDsGKStPPRKQ K637
GAB1 (rat) DLDLESGkSTPPRkQ K635-ub
S638
LDLDsGKStPPRKQK
0 6
GAB1 (human) LDLDsGKstPPRKQK S637-p
GAB1 iso2 (human) LDLDSGKSTPPRKQK S667
GAB1 (mouse) LDLDsGKStPPRKQK S638
GAB1 (rat) LDLESGkSTPPRkQK S636
T639-p
DLDsGKStPPRKQKS
0 10
GAB1 (human) DLDsGKstPPRKQKs T638-p
GAB1 iso2 (human) DLDSGKSTPPRKQKS T668
GAB1 (mouse) DLDsGKStPPRKQKS T639-p
GAB1 (rat) DLESGkSTPPRkQKN T637
K643
GKStPPRKQKSSGsG
0 2
GAB1 (human) GKstPPRKQKsSGSG K642
GAB1 iso2 (human) GKSTPPRKQKSSGSG K672
GAB1 (mouse) GKStPPRKQKSSGsG K643
GAB1 (rat) GkSTPPRkQKNSGSG K641-ub
S646
tPPRKQKSSGsGSsM
0 3
GAB1 (human) tPPRKQKsSGSGSsV S645-p
GAB1 iso2 (human) TPPRKQKSSGSGSSV S675
GAB1 (mouse) tPPRKQKSSGsGSsM S646
GAB1 (rat) TPPRkQKNSGSGSSM N644
S649-p
RKQKSSGsGSsMADE
Upstream
0 2
Treatment
  • insulin
  • LY294002
GAB1 (human) RKQKsSGSGSsVADE S648
GAB1 iso2 (human) RKQKSSGSGSSVADE S678
GAB1 (mouse) RKQKSSGsGSsMADE S649-p
GAB1 (rat) RkQKNSGSGSSMSDE S647
S652-p
KSSGsGSsMADERVD
Upstream
0 3
Treatment
  • insulin
  • LY294002
GAB1 (human) KsSGSGSsVADERVD S651-p
GAB1 iso2 (human) KSSGSGSSVADERVD S681
GAB1 (mouse) KSSGsGSsMADERVD S652-p
GAB1 (rat) KNSGSGSSMSDERVD S650
Y660-p
MADERVDyVVVDQQK
Upstream
8 1524
GAB1 (human)
Y659-p
GAB1 iso2 (human)
Y689-p
GAB1 (mouse)
Y660-p
GAB1 (rat)
Y658-p
Kinase, in vitro:
  • EGFR (mouse)
  • Met (mouse)
Regulatory protein:
  • PTP1B (human)
  • Pyk2 (mouse)
Treatment
  • EGF
  • insulin
  • PDGF
  • PF-4594755
GAB1 (human) VADERVDyVVVDQQK Y659-p
GAB1 iso2 (human) VADERVDyVVVDQQK Y689-p
GAB1 (mouse) MADERVDyVVVDQQK Y660-p
GAB1 (rat) MSDERVDyVVVDQQK Y658-p
T674
KTLALKSTREAWTDG
0 1
GAB1 (human) KTLALKStREAWTDG T673-p
GAB1 iso2 (human) KTLALKSTREAWTDG T703
GAB1 (mouse) KTLALKSTREAWTDG T674
GAB1 (rat) KTLALKSTREAWTDG T672
S684-p
AWTDGRQsTESETPt
Upstream
0 20
Treatment
  • insulin
  • LY294002
  • MK-2206
GAB1 (human) AWTDGRQstESETPA S683-p
GAB1 iso2 (human) AWTDGRQSTESETPA S713
GAB1 (mouse) AWTDGRQsTESETPt S684-p
GAB1 (rat) AWTDGRQSTESETPT S682
T685
WTDGRQsTESETPtK
0 23
GAB1 (human) WTDGRQstESETPAK T684-p
GAB1 iso2 (human) WTDGRQSTESETPAK T714
GAB1 (mouse) WTDGRQsTESETPtK T685
GAB1 (rat) WTDGRQSTESETPTK T683
T691-p
sTESETPtKNVK___
0 1
GAB1 (human) stESETPAKSVK___ A690
GAB1 iso2 (human) STESETPAKSVK___ A720
GAB1 (mouse) sTESETPtKNVK___ T691-p
GAB1 (rat) STESETPTKNVK___ T689