JNK2 (mouse)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

S129

ELDHERMsYLLYQML

Upstream

Downstream

Effects on Modified Protein

enzymatic activity, induced

Kinase, in vitro:

PKCB iso2 (human)

JNK2 (human)	ELDHERMSYLLYQML	S129
JNK2 iso2 (human)	ELDHERMSYLLYQML	S129
JNK2 iso3 (human)	ELDHERMSYLLYQML	S129
JNK2 (mouse)	ELDHERMsYLLYQML	S129
JNK2 iso4 (mouse)	ELDHERMSYLLYQML	S129
JNK2 (rat)	ELDHERMSYLLYQML	S129
JNK2 iso2 (rat)	ELDHERMSYLLYQML	S129

S144

CGIKHLHSAGIIHRD

JNK2 (human)	CGIKHLHsAGIIHRD	S144
JNK2 iso2 (human)	CGIKHLHSAGIIHRD	S144
JNK2 iso3 (human)	CGIKHLHSAGIIHRD	S144
JNK2 (mouse)	CGIKHLHSAGIIHRD	S144
JNK2 iso4 (mouse)	CGIKHLHSAGIIHRD	S144
JNK2 (rat)	CGIKHLHSAGIIHRD	S144
JNK2 iso2 (rat)	CGIKHLHSAGIIHRD	S144

T178

GLARTACTNFMMtPy

JNK2 (human)	GLARTACtNFMMtPy	T178
JNK2 iso2 (human)	GLARTACTNFMMTPy	T178
JNK2 iso3 (human)	GLARTACTNFMMTPY	T178
JNK2 (mouse)	GLARTACTNFMMtPy	T178
JNK2 iso4 (mouse)	GLARTACTNFMMTPY	T178
JNK2 (rat)	GLARTACTNFMMtPy	T178
JNK2 iso2 (rat)	GLARTACTNFMMTPY	T178

T183

ACTNFMMtPyVVtRY

Upstream

Downstream

455

Effects on Modified Protein

enzymatic activity, induced

Effects on Biological Processes:

apoptosis, induced
cell motility, induced
transcription, inhibited

Kinase, in vitro:

MKK4 (mouse)

Putative in vivo kinases:

MKK4 (human)
MKK4 (mouse)
MKK7 (human)

Regulatory protein:

Bcl-10 (mouse)
CARD11 (mouse)
Cot (human)
Cot (mouse)
Fyn (mouse)
G-alpha i2 (human)
HSF1 (human)
MEK1 (mouse)
PKR (mouse)
ROCK1 (human)
SGPL1 (mouse)
SHP-2 (human)
Src iso1 (mouse)
TRIM40 (mouse)

Treatment

activin
adriamycin
anisomycin
Aplidin
benzo(a)pyrene
etoposide
HA-1077
IL-1b
IL-33
IL-6
insulin
ionomycin
JNK_inhibitor_I
linoleic_acid
LPS
LY294002
MK-591
nerve_damage
NTCU
okadaic_acid
palmitate
PD98059
PGE2
phorbol_ester
pomegranate_wine
PTX
RANKL
rapamycin
TGF-alpha
TGF-beta
thapsigargin
thrombin
TNF
UV
virus infection
zymosan

JNK2 (human)	ACtNFMMtPyVVtRY	T183
JNK2 iso2 (human)	ACTNFMMTPyVVTRY	T183
JNK2 iso3 (human)	ACTNFMMTPYVVTRY	T183
JNK2 (mouse)	ACTNFMMtPyVVtRY	T183
JNK2 iso4 (mouse)	ACTNFMMTPYVVTRY	T183
JNK2 (rat)	ACTNFMMtPyVVTRY	T183
JNK2 iso2 (rat)	ACTNFMMTPYVVTRY	T183

Y185

TNFMMtPyVVtRYYR

Upstream

Downstream

1477

Effects on Modified Protein

enzymatic activity, induced

Effects on Biological Processes:

apoptosis, induced
cell motility, induced
transcription, inhibited

Kinase, in vitro:

MKK4 (mouse)

Putative in vivo kinases:

MKK4 (human)
MKK4 (mouse)
MKK7 (human)

Regulatory protein:

Bcl-10 (mouse)
CARD11 (mouse)
Cot (human)
Cot (mouse)
Fyn (mouse)
G-alpha i2 (human)
HSF1 (human)
MEK1 (mouse)
PKR (mouse)
ROCK1 (human)
SGPL1 (mouse)
SHP-2 (human)
Src iso1 (mouse)
TRIM40 (mouse)

Treatment

activin
adriamycin
anisomycin
Aplidin
benzo(a)pyrene
etoposide
HA-1077
IL-1b
IL-33
IL-6
insulin
ionomycin
JNK_inhibitor_I
linoleic_acid
LPS
LY294002
MK-591
nerve_damage
NTCU
okadaic_acid
palmitate
PD98059
PGE2
phorbol_ester
pomegranate_wine
PTX
RANKL
rapamycin
TGF-alpha
TGF-beta
thapsigargin
thrombin
TNF
UV
virus infection
zymosan

JNK2 (human)	tNFMMtPyVVtRYYR	Y185
JNK2 iso2 (human)	TNFMMTPyVVTRYYR	Y185
JNK2 iso3 (human)	TNFMMTPYVVTRYYR	Y185
JNK2 (mouse)	TNFMMtPyVVtRYYR	Y185
JNK2 iso4 (mouse)	TNFMMTPYVVTRYYR	Y185
JNK2 (rat)	TNFMMtPyVVTRYYR	Y185
JNK2 iso2 (rat)	TNFMMTPYVVTRYYR	Y185

T188

MMtPyVVtRYYRAPE

JNK2 (human)	MMtPyVVtRYYRAPE	T188
JNK2 iso2 (human)	MMTPyVVTRYYRAPE	T188
JNK2 iso3 (human)	MMTPYVVTRYYRAPE	T188
JNK2 (mouse)	MMtPyVVtRYYRAPE	T188
JNK2 iso4 (mouse)	MMTPYVVTRYYRAPE	T188
JNK2 (rat)	MMtPyVVTRYYRAPE	T188
JNK2 iso2 (rat)	MMTPYVVTRYYRAPE	T188

S292

ERDKIKTSQARDLLS

JNK2 (human)	ERDKIKTsQARDLLS	S292
JNK2 iso2 (human)	ERDKIKTSQARDLLS	S292
JNK2 iso3 (human)	ERDKIKTSQARDLLS	S292
JNK2 (mouse)	ERDKIKTSQARDLLS	S292
JNK2 iso4 (mouse)	ERDKIKTSQARDLLS	S292
JNK2 (rat)	ERDKIKTSQARDLLS	S292
JNK2 iso2 (rat)	ERDKIKTSQARDLLS	S292

Y357

EEWKELIYKEVMDWE

JNK2 (human)	EEWKELIyKEVMDWE	Y357
JNK2 iso2 (human)	EEWKELIYKEVMDWE	Y357
JNK2 iso3 (human)	EEWKELIYKEVMDWE	Y357
JNK2 (mouse)	EEWKELIYKEVMDWE	Y357
JNK2 iso4 (mouse)	EEWKELIYKEVMDWE	Y357
JNK2 (rat)	EEWKELIYKEVMDWE	Y357
JNK2 iso2 (rat)	EEWKELIYKEVMDWE	Y357

T403

SSMSTEHTLASDTDS

JNK2 (human)	SSMSTEQtLAsDTDS	T404
JNK2 iso2 (human)	gap	-
JNK2 iso3 (human)	gap	-
JNK2 (mouse)	SSMSTEHTLASDTDS	T403
JNK2 iso4 (mouse)	SSMSTEHTLASDTDS	T403
JNK2 (rat)	SSMSTEHTLASDTDS	T403
JNK2 iso2 (rat)	SSMSTEHTLASDTDS	T403

S406

STEHTLASDTDSSLD

JNK2 (human)	STEQtLAsDTDSSLD	S407
JNK2 iso2 (human)	gap	-
JNK2 iso3 (human)	gap	-
JNK2 (mouse)	STEHTLASDTDSSLD	S406
JNK2 iso4 (mouse)	STEHTLASDTDSSLD	S406
JNK2 (rat)	STEHTLASDTDSSLD	S406
JNK2 iso2 (rat)	STEHTLASDTDSSLD	S406