Other Species / Isoforms
  FOXO1A (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S22
EPLPRQRSCtWPLPR
1 0
FOXO1A (human) EPLPRPRsCtWPLPR S22-p
FOXO1A (mouse) EPLPRQRSCtWPLPR S22
FOXO1A (rat) EPLPRQRSCtWPLPR S22
T24-p
LPRQRSCtWPLPRPE
Upstream
Downstream
53 45
FOXO1A (human)
T24-p
FOXO1A (mouse)
T24-p
FOXO1A (rat)
T24-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (mouse)
Putative in vivo kinases:
  • Akt1 (mouse)
Regulatory protein:
  • INSR (mouse)
  • PTEN (mouse)
  • RICTOR (mouse)
  • Sin1 (mouse)
  • TSC1 (mouse)
Treatment
  • anti-IgM
  • Dynasore
  • fasting
  • IGF-1
  • insulin
  • KU-0063794
  • rapamycin
  • refeeding
  • rosiglitazone
  • serum
  • wortmannin
FOXO1A (human) LPRPRsCtWPLPRPE T24-p
FOXO1A (mouse) LPRQRSCtWPLPRPE T24-p
FOXO1A (rat) LPRQRSCtWPLPRPE T24-p
S150-p
AGQPRKTsSSRRNAW
Upstream
1 0
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • cAMP_analog
  • glucagon
  • H-89
FOXO1A (human) AGQPRKSsSSRRNAW S153-p
FOXO1A (mouse) AGQPRKTsSSRRNAW S150-p
FOXO1A (rat) AGQPRKTSSSRRNAW S147
T179
SSAEKRLTLSQIYEW
1 0
FOXO1A (human) SSAEKRLtLSQIYEW T182-p
FOXO1A (mouse) SSAEKRLTLSQIYEW T179
FOXO1A (rat) SSAEKRLTLSQIYEW T176
S209-p
SSAGWKNsIRHNLSL
Downstream
3 0
Effects on Modified Protein
  • protein stabilization
FOXO1A (human) SSAGWKNsIRHNLsL S212-p
FOXO1A (mouse) SSAGWKNsIRHNLSL S209-p
FOXO1A (rat) SSAGWKNsIRHNLSL S206-p
S215
NsIRHNLSLHSKFIR
1 1
FOXO1A (human) NsIRHNLsLHSkFIR S218-p
FOXO1A (mouse) NsIRHNLSLHSKFIR S215
FOXO1A (rat) NsIRHNLSLHSKFIR S212
K219
HNLSLHSKFIRVQNE
1 0
FOXO1A (human) HNLsLHSkFIRVQNE K222-ac
FOXO1A (mouse) HNLSLHSKFIRVQNE K219
FOXO1A (rat) HNLSLHSKFIRVQNE K216
S231
QNEGTGKSSWWMLNP
1 0
FOXO1A (human) QNEGTGKssWWMLNP S234-p
FOXO1A (mouse) QNEGTGKSSWWMLNP S231
FOXO1A (rat) QNEGTGKSSWWMLNP S228
S232
NEGTGKSSWWMLNPE
1 0
FOXO1A (human) NEGTGKssWWMLNPE S235-p
FOXO1A (mouse) NEGTGKSSWWMLNPE S232
FOXO1A (rat) NEGTGKSSWWMLNPE S229
K242
MLNPEGGKSGKsPRR
7 0
FOXO1A (human) MLNPEGGkSGksPrR K245-ac
FOXO1A (mouse) MLNPEGGKSGKsPRR K242
FOXO1A (rat) MLNPEGGKSGKsPRR K239
K245
PEGGKSGKsPRRRAA
7 0
FOXO1A (human) PEGGkSGksPrRrAA K248-ac
FOXO1A (mouse) PEGGKSGKsPRRRAA K245
FOXO1A (rat) PEGGKSGKsPRRRAA K242
S246-p
EGGKSGKsPRRRAAs
Upstream
Downstream
12 3
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CDK1 (human)
  • CDK2 (human)
  • CDK5 (human)
  • ERK2 (mouse)
Putative in vivo kinases:
  • CDK1 (mouse)
  • ERK2 (mouse)
Regulatory protein:
  • SIRT6 (human)
Treatment
  • free_fatty_acids
  • KCl_withdrawal
  • nocodazole
  • rosiglitazone
  • seliciclib
FOXO1A (human) EGGkSGksPrRrAAs S249-p
FOXO1A (mouse) EGGKSGKsPRRRAAs S246-p
FOXO1A (rat) EGGKSGKsPRRRAAs S243-p
R248
GKSGKsPRRRAAsMD
1 0
FOXO1A (human) GkSGksPrRrAAsMD R251-me
FOXO1A (mouse) GKSGKsPRRRAAsMD R248
FOXO1A (rat) GKSGKsPRRRAAsMD R245
R250
SGKsPRRRAAsMDNN
1 0
FOXO1A (human) SGksPrRrAAsMDNN R253-me
FOXO1A (mouse) SGKsPRRRAAsMDNN R250
FOXO1A (rat) SGKsPRRRAAsMDNN R247
S253-p
sPRRRAAsMDNNSKF
Upstream
Downstream
79 54
FOXO1A (human)
S256-p
FOXO1A (mouse)
S253-p
FOXO1A (rat)
S250-p
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (mouse)
Phosphatases, in vitro:
  • DUSP6 (mouse)
Putative in vivo kinases:
  • Akt1 (mouse)
Putative upstream phosphatases:
  • DUSP6 (human)
  • DUSP6 (mouse)
Regulatory protein:
  • Akt1 (mouse)
  • Akt2 (mouse)
  • BAG1 (mouse)
  • BAG4 (mouse)
  • CTLA-4 (mouse)
  • DICER1 (mouse)
  • GRB10 (human)
  • LIMS1 (human)
  • LIMS1 (mouse)
  • LPIN1 (mouse)
  • PDK1 (mouse)
  • TORC2 (mouse)
  • VEGF (human)
Treatment
  • 4-HT
  • anti-CD3/CD28
  • EGF
  • fasting
  • H2O2
  • hepatitis C virus expression
  • IGF-1
  • IGFBP-4
  • IL-3
  • insulin
  • L803-mts
  • miRNA
  • PDGF
  • rapamycin
  • refeeding
  • siRNA
  • TGF-beta
  • U0126
  • Wnt
  • wortmannin
FOXO1A (human) sPrRrAAsMDNNSkF S256-p
FOXO1A (mouse) sPRRRAAsMDNNSKF S253-p
FOXO1A (rat) sPRRRAAsMDNNSkF S250-p
K259
AsMDNNSKFAKSRGR
5 1
FOXO1A (human) AsMDNNSkFAkSRSR K262-ac
FOXO1A (mouse) AsMDNNSKFAKSRGR K259
FOXO1A (rat) AsMDNNSkFAKSRGR K256-ac
K262
DNNSKFAKSRGRAAK
7 0
FOXO1A (human) DNNSkFAkSRSRAAK K265-ac
FOXO1A (mouse) DNNSKFAKSRGRAAK K262
FOXO1A (rat) DNNSkFAKSRGRAAK K259
K271
RGRAAKKKAsLQSGQ
3 0
FOXO1A (human) RSRAAKKkAsLQSGQ K274-ac
FOXO1A (mouse) RGRAAKKKAsLQSGQ K271
FOXO1A (rat) RGRAAKKKASLQSGQ K268
S273-p
RAAKKKAsLQSGQEG
Upstream
1 1
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • cAMP_analog
  • glucagon
  • H-89
  • high-fat diet
FOXO1A (human) RAAKKkAsLQSGQEG S276-p
FOXO1A (mouse) RAAKKKAsLQSGQEG S273-p
FOXO1A (rat) RAAKKKASLQSGQEG S270
S284-p
GQEGPGDsPGSQFSK
Upstream
Downstream
4 26
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • ERK2 (mouse)
  • P38A (mouse)
FOXO1A (human) GQEGAGDsPGSQFsk S287-p
FOXO1A (mouse) GQEGPGDsPGSQFSK S284-p
FOXO1A (rat) GQEGPGDsPGSQFSK S281-p
S290
DsPGSQFSKWPAsPG
0 1
FOXO1A (human) DsPGSQFskWPAsPG S293-p
FOXO1A (mouse) DsPGSQFSKWPAsPG S290
FOXO1A (rat) DsPGSQFSKWPASPG S287
K291
sPGSQFSKWPAsPGS
1 0
FOXO1A (human) sPGSQFskWPAsPGs K294-ac
FOXO1A (mouse) sPGSQFSKWPAsPGS K291
FOXO1A (rat) sPGSQFSKWPASPGS K288
S295-p
QFSKWPAsPGSHsND
Upstream
Downstream
6 41
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • ERK2 (mouse)
  • P38A (mouse)
Treatment
  • insulin
  • U0126
FOXO1A (human) QFskWPAsPGsHsND S298-p
FOXO1A (mouse) QFSKWPAsPGSHsND S295-p
FOXO1A (rat) QFSKWPASPGSHSND S292
S298
KWPAsPGSHsNDDFD
0 8
FOXO1A (human) kWPAsPGsHsNDDFD S301-p
FOXO1A (mouse) KWPAsPGSHsNDDFD S298
FOXO1A (rat) KWPASPGSHSNDDFD S295
S300-p
PAsPGSHsNDDFDNW
Upstream
0 9
Treatment
  • insulin
FOXO1A (human) PAsPGsHsNDDFDNW S303-p
FOXO1A (mouse) PAsPGSHsNDDFDNW S300-p
FOXO1A (rat) PASPGSHSNDDFDNW S297
T314
WSTFRPRTSsNAstI
1 0
FOXO1A (human) WSTFRPRtssNAstI T317-gl
FOXO1A (mouse) WSTFRPRTSsNAstI T314
FOXO1A (rat) WSTFRPRTSsNAsTI T311
S315
STFRPRTSsNAstIS
1 0
FOXO1A (human) STFRPRtssNAstIs S318-gl
FOXO1A (mouse) STFRPRTSsNAstIS S315
FOXO1A (rat) STFRPRTSsNAsTIs S312
S316-p
TFRPRTSsNAstISG
Upstream
Downstream
25 30
FOXO1A (human)
S319-p
FOXO1A (mouse)
S316-p
FOXO1A (rat)
S313-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • Akt1 (mouse)
Treatment
  • IGF-1
  • insulin
FOXO1A (human) TFRPRtssNAstIsG S319-p
FOXO1A (mouse) TFRPRTSsNAstISG S316-p
FOXO1A (rat) TFRPRTSsNAsTIsG S313-p
S319-p
PRTSsNAstISGRLs
Downstream
6 0
Effects on Biological Processes:
  • transcription, inhibited
FOXO1A (human) PRtssNAstIsGRLs S322-p
FOXO1A (mouse) PRTSsNAstISGRLs S319-p
FOXO1A (rat) PRTSsNAsTIsGRLs S316-p
T320-p
RTSsNAstISGRLsP
0 2
FOXO1A (human) RtssNAstIsGRLsP T323-p
FOXO1A (mouse) RTSsNAstISGRLsP T320-p
FOXO1A (rat) RTSsNAsTIsGRLsP T317
S322
SsNAstISGRLsPIM
5 0
FOXO1A (human) ssNAstIsGRLsPIM S325-p
FOXO1A (mouse) SsNAstISGRLsPIM S322
FOXO1A (rat) SsNAsTIsGRLsPIM S319-p
S326-p
stISGRLsPIMtEQD
Upstream
Downstream
11 31
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Putative in vivo kinases:
  • ERK1 (mouse)
  • ERK2 (mouse)
  • P38A (mouse)
Treatment
  • insulin
  • LY294002
  • Trametinib
FOXO1A (human) stIsGRLsPIMtEQD S329-p
FOXO1A (mouse) stISGRLsPIMtEQD S326-p
FOXO1A (rat) sTIsGRLsPIMTEQD S323-p
T330-p
GRLsPIMtEQDDLGD
0 3
FOXO1A (human) GRLsPIMtEQDDLGE T333-p
FOXO1A (mouse) GRLsPIMtEQDDLGD T330-p
FOXO1A (rat) GRLsPIMTEQDDLGD T327
S380-p
DNLNLLSsPTSLTVS
2 0
FOXO1A (human) DNLNLLSsPTSLTVS S383-p
FOXO1A (mouse) DNLNLLSsPTSLTVS S380-p
FOXO1A (rat) DNLNLLSSPTSLTVS S377
S391-p
LTVSTQSsPGSMMQQ
1 0
FOXO1A (human) LTVSTQSsPGTMMQQ S394-p
FOXO1A (mouse) LTVSTQSsPGSMMQQ S391-p
FOXO1A (rat) LTVSTQSSPGSMMQQ S388
T399-p
PGSMMQQtPCYSFAP
1 0
FOXO1A (human) PGTMMQQtPCYSFAP T402-p
FOXO1A (mouse) PGSMMQQtPCYSFAP T399-p
FOXO1A (rat) PGSMMQQTPCYSFAP T396
S413-p
PPNTSLNsPsPNYSK
Upstream
Downstream
4 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (mouse)
  • P38A (mouse)
Putative in vivo kinases:
  • ERK2 (mouse)
FOXO1A (human) PPNTSLNsPsPNYQK S416-p
FOXO1A (mouse) PPNTSLNsPsPNYSK S413-p
FOXO1A (rat) PPNTSLNSPSPNYAK S410
S415-p
NTSLNsPsPNYSKYT
Upstream
Downstream
4 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (mouse)
Putative in vivo kinases:
  • ERK2 (mouse)
FOXO1A (human) NTSLNsPsPNYQKYT S418-p
FOXO1A (mouse) NTSLNsPsPNYSKYT S415-p
FOXO1A (rat) NTSLNSPSPNYAKYT S412
S429-p
TYGQSSMsPLPQMPM
Upstream
Downstream
2 3
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (mouse)
  • P38A (mouse)
Putative in vivo kinases:
  • ERK2 (mouse)
FOXO1A (human) TYGQSSMsPLPQMPI S432-p
FOXO1A (mouse) TYGQSSMsPLPQMPM S429-p
FOXO1A (rat) TYGQSSMSPVPQMPM S426
T464-p
GLLKELLtsDsPPHN
0 3
FOXO1A (human) GLLKELLtSDsPPHN T467-p
FOXO1A (mouse) GLLKELLtsDsPPHN T464-p
FOXO1A (rat) GLLKELLTSDSPPHN T461
S465-p
LLKELLtsDsPPHND
0 1
FOXO1A (human) LLKELLtSDsPPHND S468
FOXO1A (mouse) LLKELLtsDsPPHND S465-p
FOXO1A (rat) LLKELLTSDSPPHND S462
S467-p
KELLtsDsPPHNDIM
Upstream
Downstream
3 10
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (mouse)
  • P38A (mouse)
Putative in vivo kinases:
  • ERK2 (mouse)
  • P38A (mouse)
FOXO1A (human) KELLtSDsPPHNDIM S470-p
FOXO1A (mouse) KELLtsDsPPHNDIM S467-p
FOXO1A (rat) KELLTSDSPPHNDIM S464
S475-p
PPHNDIMsPVDPGVA
Upstream
Downstream
3 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (mouse)
  • P38A (mouse)
Putative in vivo kinases:
  • ERK2 (mouse)
  • P38A (mouse)
FOXO1A (human) PPHNDIMTPVDPGVA T478
FOXO1A (mouse) PPHNDIMsPVDPGVA S475-p
FOXO1A (rat) PPHNDIMSPVDPGVA S472
S499-p
NVMMGPNsVMPAYGS
Downstream
1 0
Effects on Biological Processes:
  • transcription, inhibited
FOXO1A (human) NVMMGPNSVMsTYGs S502
FOXO1A (mouse) NVMMGPNsVMPAYGS S499-p
FOXO1A (rat) NVLMGPNSVMPAYGS S496
P502
MGPNsVMPAYGSQAS
0 1
FOXO1A (human) MGPNSVMsTYGsQAS S505-p
FOXO1A (mouse) MGPNsVMPAYGSQAS P502
FOXO1A (rat) MGPNSVMPAYGSQAP P499
S506
sVMPAYGSQASHNKM
0 1
FOXO1A (human) SVMsTYGsQASHNKM S509-p
FOXO1A (mouse) sVMPAYGSQASHNKM S506
FOXO1A (rat) SVMPAYGSQAPHNKM S503
S547
VNTMPHTSAMNRLtP
1 0
FOXO1A (human) VSTMPHTsGMNRLTQ S550-gl
FOXO1A (mouse) VNTMPHTSAMNRLtP S547
FOXO1A (rat) VNTMPHTSAMNRLTP S544
T553-p
TSAMNRLtPVKtPLQ
1 1
FOXO1A (human) TsGMNRLTQVKTPVQ T556
FOXO1A (mouse) TSAMNRLtPVKtPLQ T553-p
FOXO1A (rat) TSAMNRLTPVKTPLQ T550
T557-p
NRLtPVKtPLQVPLS
Upstream
1 0
Kinase, in vitro:
  • ERK2 (mouse)
  • P38A (mouse)
FOXO1A (human) NRLTQVKTPVQVPLP T560
FOXO1A (mouse) NRLtPVKtPLQVPLS T557-p
FOXO1A (rat) NRLTPVKTPLQVPLS T554
K594
MGVLHQEKLPSDLDG
0 1
FOXO1A (human) MGLLHQEkLPSDLDG K597-ac
FOXO1A (mouse) MGVLHQEKLPSDLDG K594
FOXO1A (rat) MGVLHQEKLPSDLDG K591
T645
FPHSVKTTTHSWVSG
1 0
FOXO1A (human) FPHSVKTttHsWVsG T648-gl
FOXO1A (mouse) FPHSVKTTTHSWVSG T645
FOXO1A (rat) FPHSVKTTTHSWVSG T642
T646
PHSVKTTTHSWVSG_
1 0
FOXO1A (human) PHSVKTttHsWVsG_ T649-p
FOXO1A (mouse) PHSVKTTTHSWVSG_ T646
FOXO1A (rat) PHSVKTTTHSWVSG_ T643
S648
SVKTTTHSWVSG___
0 1
FOXO1A (human) SVKTttHsWVsG___ S651-p
FOXO1A (mouse) SVKTTTHSWVSG___ S648
FOXO1A (rat) SVKTTTHSWVSG___ S645
S651
TTTHSWVSG______
1 0
FOXO1A (human) TttHsWVsG______ S654-gl
FOXO1A (mouse) TTTHSWVSG______ S651
FOXO1A (rat) TTTHSWVSG______ S648