Other Species / Isoforms
  STING (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
C12
SLHPSIPCPRGHGAQ
0 1
STING (human) SLHPSIPCPRGHGAQ C12
STING iso3 (human) gap -
STING (mouse) NLHPAIPRPRGHRSK R12
STING iso2 (mouse) NLHPAIPrPRGHRSK R61-m1
STING (rat) NLHPSIPRPRSYRFK R12
T84-p
YRGSYWRtVRACLGC
0 1
STING (human) YRGSYWRtVRACLGC T84-p
STING iso3 (human) gap -
STING (mouse) YQGSYWKAVRACLGC A84
STING iso2 (mouse) YQGSYWKAVRACLGC A133
STING (rat) YQGSYWKAVRACVGS A84
K150-ub
EISAVCEkGNFNVAH
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, inhibited
Treatment
  • virus infection
STING (human) EISAVCEkGNFNVAH K150-ub
STING iso3 (human) gap -
STING (mouse) EVSAVCEEKKLNVAH E149
STING iso2 (mouse) EVSAVCEEKKLNVAH E198
STING (rat) EVSAVCEEKNFNVAH E150
T181-p
ELQARIRtYNQHYNN
1 1
STING (human) ELQARIRtYNQHYNN T181-p
STING iso3 (human) ELQARIRTYNQHYNN T33
STING (mouse) GLQARIRMFNQLHNN M180
STING iso2 (mouse) GLQARIRMFNQLHNN M229
STING (rat) GLQARIRMFNQLHNN M181
T229-p
LDKLPQQtGDHAGIk
Upstream
1 1
Putative in vivo kinases:
  • TAK1 (human)
STING (human) LDKLPQQtGDHAGIk T229-p
STING iso3 (human) LDKLPQQTGDHAGIK T81
STING (mouse) RDMLPQQNIDRAGIk N228
STING iso2 (mouse) RDMLPQQNIDRAGIK N277
STING (rat) RDMLPQQNTDRAGVK N229
T229-gl
LDKLPQQtGDHAGIk
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, altered
STING (human) LDKLPQQtGDHAGIk T229-gl
STING iso3 (human) LDKLPQQTGDHAGIK T81
STING (mouse) RDMLPQQNIDRAGIk N228
STING iso2 (mouse) RDMLPQQNIDRAGIK N277
STING (rat) RDMLPQQNTDRAGVK N229
K236-ub
tGDHAGIkDRVysNS
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
STING (human) tGDHAGIkDRVysNS K236-ub
STING iso3 (human) TGDHAGIKDRVYSNS K88
STING (mouse) NIDRAGIkNRVYSNS K235-ub
STING iso2 (mouse) NIDRAGIKNRVYSNS K284
STING (rat) NTDRAGVKNRAYSNS K236
Y240-p
AGIkDRVysNSIyEL
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
Effects on Biological Processes:
  • transcription, induced
Putative in vivo kinases:
  • Syk (human)
Regulatory protein:
  • EGFR (human)
Treatment
  • cGAMP
  • Fostamatinib
  • gefitinib
  • R406
  • siRNA
view more >
STING (human) AGIkDRVysNSIyEL Y240-p
STING iso3 (human) AGIKDRVYSNSIYEL Y92
STING (mouse) AGIkNRVYSNSVYEI Y239
STING iso2 (mouse) AGIKNRVYSNSVYEI Y288
STING (rat) AGVKNRAYSNSVYEL Y240
S241-p
GIkDRVysNSIyELL
Upstream
1 1
Putative in vivo kinases:
  • TAK1 (human)
STING (human) GIkDRVysNSIyELL S241-p
STING iso3 (human) GIKDRVYSNSIYELL S93
STING (mouse) GIkNRVYSNSVYEIL S240
STING iso2 (mouse) GIKNRVYSNSVYEIL S289
STING (rat) GVKNRAYSNSVYELL S241
Y245-p
RVysNSIyELLENGQ
Upstream
Downstream
4 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • autophagy, inhibited
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • EGFR (human)
Putative in vivo kinases:
  • EGFR (human)
  • Src (human)
Putative upstream phosphatases:
  • PTP1B (human)
  • PTPN2 (human)
Regulatory protein:
  • STAT2 (human)
Treatment
  • cGAMP
  • gefitinib
  • genistein
  • osimertinib
  • R406
  • siRNA
  • virus infection
view more >
STING (human) RVysNSIyELLENGQ Y245-p
STING iso3 (human) RVYSNSIYELLENGQ Y97
STING (mouse) RVYSNSVYEILENGQ Y244
STING iso2 (mouse) RVYSNSVYEILENGQ Y293
STING (rat) RAYSNSVYELLENGQ Y245
T256-p
ENGQRAGtCVLEYAt
1 1
STING (human) ENGQRAGtCVLEYAt T256-p
STING iso3 (human) ENGQRAGTCVLEYAT T108
STING (mouse) ENGQPAGVCILEYAT V255
STING iso2 (mouse) ENGQPAGVCILEYAT V304
STING (rat) ENGQPAGACILEYAT A256
T263-p
tCVLEYAtPLQTLFA
1 1
STING (human) tCVLEYAtPLQTLFA T263-p
STING iso3 (human) TCVLEYATPLQTLFA T115
STING (mouse) VCILEYATPLQTLFA T262
STING iso2 (mouse) VCILEYATPLQTLFA T311
STING (rat) ACILEYATPLQTLFA T263
K289-ub
EDRLEQAkLFCRTLE
1 2
STING (human) EDRLEQAkLFCRTLE K289-ub
STING iso3 (human) EDRLEQAKLFCRTLE K141
STING (mouse) EDRLEQAkLFCRTLE K288-ub
STING iso2 (mouse) EDRLEQAKLFCRTLE K337
STING (rat) EDRLEQAKLFCRTLE K289
K338-ac
RHLRQEEkEEVtVGs
Downstream
1 1
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • autophagy, induced
  • signaling pathway regulation
STING (human) RHLRQEEkEEVtVGs K338-ac
STING iso3 (human) RHLRQEEKEEVTVGS K190
STING (mouse) RHIRQEEKEEVTMNA K337
STING iso2 (mouse) RHIRQEEKEEVTMNA K386
STING (rat) RHIRQEEKEEVTMSG K338
K338-ub
RHLRQEEkEEVtVGs
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
Regulatory protein:
  • UFL1 (human)
STING (human) RHLRQEEkEEVtVGs K338-ub
STING iso3 (human) RHLRQEEKEEVTVGS K190
STING (mouse) RHIRQEEKEEVTMNA K337
STING iso2 (mouse) RHIRQEEKEEVTMNA K386
STING (rat) RHIRQEEKEEVTMSG K338
K338
RHLRQEEKEEVtVGs
1 0
STING (human) RHLRQEEKEEVtVGs K338
STING iso3 (human) RHLRQEEKEEVTVGS K190
STING (mouse) RHIRQEEkEEVTMNA K337-sm
STING iso2 (mouse) RHIRQEEKEEVTMNA K386
STING (rat) RHIRQEEKEEVTMSG K338
T342-p
QEEkEEVtVGsLkts
1 1
STING (human) QEEkEEVtVGsLkts T342-p
STING iso3 (human) QEEKEEVTVGSLKTS T194
STING (mouse) QEEkEEVTMNAPMTS T341
STING iso2 (mouse) QEEKEEVTMNAPMTS T390
STING (rat) QEEKEEVTMSGPPTS T342
S345-p
kEEVtVGsLktsAVP
0 1
STING (human) kEEVtVGsLktsAVP S345-p
STING iso3 (human) KEEVTVGSLKTSAVP S197
STING (mouse) kEEVTMNAPMTSVAP A344
STING iso2 (mouse) KEEVTMNAPMTSVAP A393
STING (rat) KEEVTMSGPPTSVAP G345
K347-ub
EVtVGsLktsAVPSt
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Regulatory protein:
  • UFL1 (human)
STING (human) EVtVGsLktsAVPSt K347-ub
STING iso3 (human) EVTVGSLKTSAVPST K199
STING (mouse) EVTMNAPMTSVAPPP M346
STING iso2 (mouse) EVTMNAPMTSVAPPP M395
STING (rat) EVTMSGPPTSVAPRP P347
T348-p
VtVGsLktsAVPSts
1 1
STING (human) VtVGsLktsAVPSts T348-p
STING iso3 (human) VTVGSLKTSAVPSTS T200
STING (mouse) VTMNAPMTSVAPPPS T347
STING iso2 (mouse) VTMNAPMTSVAPPPS T396
STING (rat) VTMSGPPTSVAPRPS T348
S349-p
tVGsLktsAVPStst
1 1
STING (human) tVGsLktsAVPStst S349-p
STING iso3 (human) TVGSLKTSAVPSTST S201
STING (mouse) TMNAPMTSVAPPPSV S348
STING iso2 (mouse) TMNAPMTSVAPPPSV S397
STING (rat) TMSGPPTSVAPRPSL S349
T354-p
ktsAVPStstMsQEP
Upstream
1 1
Putative in vivo kinases:
  • TAK1 (human)
STING (human) ktsAVPStstMsQEP T354-p
STING iso3 (human) KTSAVPSTSTMSQEP T206
STING (mouse) MTSVAPPPSVLsQEP P353
STING iso2 (mouse) MTSVAPPPSVLSQEP P402
STING (rat) PTSVAPRPSLLSQEP P354
S355-p
tsAVPStstMsQEPE
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • transcription, induced
Kinase, in vitro:
  • TAK1 (human)
Putative in vivo kinases:
  • TAK1 (human)
Treatment
  • cGAMP
  • ISD
  • TAK1_inhibitor
view more >
STING (human) tsAVPStstMsQEPE S355-p
STING iso3 (human) TSAVPSTSTMSQEPE S207
STING (mouse) TSVAPPPSVLsQEPR S354
STING iso2 (mouse) TSVAPPPSVLSQEPR S403
STING (rat) TSVAPRPSLLSQEPR S355
T356-p
sAVPStstMsQEPEL
Upstream
1 1
Putative in vivo kinases:
  • TAK1 (human)
STING (human) sAVPStstMsQEPEL T356-p
STING iso3 (human) SAVPSTSTMSQEPEL T208
STING (mouse) SVAPPPSVLsQEPRL V355
STING iso2 (mouse) SVAPPPSVLSQEPRL V404
STING (rat) SVAPRPSLLSQEPRL L356
S358-p
VPStstMsQEPELLI
Upstream
Downstream
4 2
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Putative in vivo kinases:
  • TBK1 (human)
Treatment
  • virus infection
STING (human) VPStstMsQEPELLI S358-p
STING iso3 (human) VPSTSTMSQEPELLI S210
STING (mouse) APPPSVLsQEPRLLI S357-p
STING iso2 (mouse) APPPSVLSQEPRLLI S406
STING (rat) APRPSLLSQEPRLLI S358
S366-p
QEPELLIsGMEkPLP
Upstream
Downstream
42 3
STING (human)
S366-p
STING (mouse)
S365-p
STING iso2 (mouse)
S414-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, inhibited
  • signaling pathway regulation
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • TBK1 (human)
  • ULK1 (human)
  • ULK2 (human)
view more >
Putative in vivo kinases:
  • TBK1 (human)
  • ULK1 (human)
Regulatory protein:
  • ACBD3 (human)
  • AP1B1 (human)
  • AP1G1 (human)
  • AP1S1 (human)
  • cGAS (human)
  • DDX3 (human)
  • DDX41 (human)
  • EGFR (human)
  • IFITM3 (human)
  • IKKE (human)
  • IRF3 (human)
  • IRF8 (human)
  • LRRK2 (human)
  • MEF2A (human)
  • MIS18A (human)
  • NFkB-p65 (human)
  • PD-L1 (human)
  • PTP1B (human)
  • PTPN2 (human)
  • SACM1L (human)
  • SLC19A1 (human)
  • STAT2 (human)
  • STEEP1 (human)
  • STING (human)
  • TBK1 (human)
  • Tip60 (human)
  • TRIM10 (human)
view more >
Treatment
  • 2'3'-RR c-di-AMP
  • ADU-S100
  • AZD6738
  • BX795
  • C-176
  • cGAMP
  • compound 53
  • compound_8
  • DMXAA
  • dsDNA
  • G10
  • gefitinib
  • H-151
  • HOCl
  • hydroxyurea
  • ISD
  • itraconazol
  • phosphatidylinositol-3-phosphate
  • poly(I-C)
  • preformed fibrils
  • reversine
  • RO-3306
  • siRNA
  • TAK1_inhibitor
  • TDI-8246
  • TPCA1
  • VE-821
  • virus infection
view more >
STING (human) QEPELLIsGMEkPLP S366-p
STING iso3 (human) QEPELLISGMEKPLP S218
STING (mouse) QEPRLLIsGMDQPLP S365-p
STING iso2 (mouse) QEPRLLISGMDQPLP S414
STING (rat) QEPRLLISGMEQPLP S366
K370-ub
LLIsGMEkPLPLRTD
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
Regulatory protein:
  • UFL1 (human)
STING (human) LLIsGMEkPLPLRTD K370-ub
STING iso3 (human) LLISGMEKPLPLRTD K222
STING (mouse) LLIsGMDQPLPLRTD Q369
STING iso2 (mouse) LLISGMDQPLPLRTD Q418
STING (rat) LLISGMEQPLPLRTD Q370