Other Species / Isoforms
  PTEN (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K6
__MTAIIKEIVSRNK
0 1
PTEN (human) __MTAIIkEIVSRNk K6-ac
PTEN iso2 (human) PDMTAIIKEIVSRNK K179
PTEN (mouse) __MTAIIKEIVSRNK K6
PTEN (rat) __MTAIIKEIVSRNK K6
K6
__MTAIIKEIVSRNK
0 1
PTEN (human) __MTAIIkEIVSRNk K6-ub
PTEN iso2 (human) under review -
PTEN (mouse) __MTAIIKEIVSRNK K6
PTEN (rat) __MTAIIKEIVSRNK K6
K13
KEIVSRNKRRYQEDG
4 0
PTEN (human) kEIVSRNkRRYQEDG K13-ub
PTEN iso2 (human) KEIVSRNKRRYQEDG K186
PTEN (mouse) KEIVSRNKRRYQEDG K13
PTEN (rat) KEIVSRNKRRYQEDG K13
Y27
GFDLDLTYIYPNIIA
1 0
PTEN (human) GFDLDLTyIYPNIIA Y27-p
PTEN iso2 (human) GFDLDLTYIYPNIIA Y200
PTEN (mouse) GFDLDLTYIYPNIIA Y27
PTEN (rat) GFDLDLTYIYPNIIA Y27
Y46-p
AERLEGVyRNNIDDV
1 45
PTEN (human) AERLEGVyRNNIDDV Y46-p
PTEN iso2 (human) AERLEGVYRNNIDDV Y219
PTEN (mouse) AERLEGVyRNNIDDV Y46-p
PTEN (rat) AERLEGVYRNNIDDV Y46
K66-ub
SKHKNHYkIYNLCAE
1 2
PTEN (human) SKHKNHYkIyNLCAE K66-ub
PTEN iso2 (human) SKHKNHYKIYNLCAE K239
PTEN (mouse) SKHKNHYkIYNLCAE K66-ub
PTEN (rat) SKHKNHYKIYNLCAE K66
Y68
HKNHYkIYNLCAERH
2 1
PTEN (human) HKNHYkIyNLCAERH Y68-p
PTEN iso2 (human) HKNHYKIYNLCAERH Y241
PTEN (mouse) HKNHYkIYNLCAERH Y68
PTEN (rat) HKNHYKIYNLCAERH Y68
K80-ub
ERHYDTAkFNCRVAQ
1 3
PTEN (human) ERHYDTAkFNCRVAQ K80-ub
PTEN iso2 (human) ERHYDTAKFNCRVAQ K253
PTEN (mouse) ERHYDTAkFNCRVAQ K80-ub
PTEN (rat) ERHYDTAKFNCRVAQ K80
S113
EDLDQWLSEDDNHVA
1 1
PTEN (human) EDLDQWLsEDDNHVA S113-p
PTEN iso2 (human) EDLDQWLSEDDNHVA S286
PTEN (mouse) EDLDQWLSEDDNHVA S113
PTEN (rat) EDLDQWLsEDDNHVA S113-p
K125
HVAAIHCKAGKGRTG
2 0
PTEN (human) HVAAIHCkAGkGRTG K125-ac
PTEN iso2 (human) HVAAIHCKAGKGRTG K298
PTEN (mouse) HVAAIHCKAGKGRTG K125
PTEN (rat) HVAAIHCKAGKGRTG K125
K128
AIHCKAGKGRTGVMI
2 0
PTEN (human) AIHCkAGkGRTGVMI K128-ac
PTEN iso2 (human) AIHCKAGKGRTGVMI K301
PTEN (mouse) AIHCKAGKGRTGVMI K128
PTEN (rat) AIHCKAGKGRTGVMI K128
Y138
TGVMICAYLLHRGKF
2 0
PTEN (human) TGVMICAyLLHRGKF Y138-p
PTEN iso2 (human) TGVMICAYLLHRGKF Y311
PTEN (mouse) TGVMICAYLLHRGKF Y138
PTEN (rat) TGVMICAYLLHRGKF Y138
Y155
AQEALDFYGEVRTRD
2 1
PTEN (human) AQEALDFyGEVRTRD Y155-p
PTEN iso2 (human) AQEALDFYGEVRTRD Y328
PTEN (mouse) AQEALDFYGEVRTRD Y155
PTEN (rat) AQEALDFYGEVRTRD Y155
K163
GEVRTRDKKGVTIPS
1 1
PTEN (human) GEVRTRDkkGVTIPS K163-ac
PTEN iso2 (human) GEVRTRDKKGVTIPS K336
PTEN (mouse) GEVRTRDKKGVTIPS K163
PTEN (rat) GEVRTRDKKGVTIPS K163
K164
EVRTRDKKGVTIPSQ
0 1
PTEN (human) EVRTRDkkGVTIPSQ K164-ac
PTEN iso2 (human) EVRTRDKKGVTIPSQ K337
PTEN (mouse) EVRTRDKKGVTIPSQ K164
PTEN (rat) EVRTRDKKGVTIPSQ K164
Y174-p
TIPSQRRyVyyySYL
2 13
PTEN (human) TIPSQRRyVyyysyL Y174-p
PTEN iso2 (human) TIPSQRRYVYYYSYL Y347
PTEN (mouse) TIPSQRRyVyyySYL Y174-p
PTEN (rat) TIPSQRRYVYYYSYL Y174
Y176-p
PSQRRyVyyySYLLK
0 11
PTEN (human) PSQRRyVyyysyLLK Y176-p
PTEN iso2 (human) PSQRRYVYYYSYLLK Y349
PTEN (mouse) PSQRRyVyyySYLLK Y176-p
PTEN (rat) PSQRRYVYYYSYLLK Y176
Y177-p
SQRRyVyyySYLLKN
0 11
PTEN (human) SQRRyVyyysyLLKN Y177-p
PTEN iso2 (human) SQRRYVYYYSYLLKN Y350
PTEN (mouse) SQRRyVyyySYLLKN Y177-p
PTEN (rat) SQRRYVYYYSYLLKN Y177
Y178-p
QRRyVyyySYLLKNH
0 11
PTEN (human) QRRyVyyysyLLKNH Y178-p
PTEN iso2 (human) QRRYVYYYSYLLKNH Y351
PTEN (mouse) QRRyVyyySYLLKNH Y178-p
PTEN (rat) QRRYVYYYSYLLKNH Y178
S179
RRyVyyySYLLKNHL
0 3
PTEN (human) RRyVyyysyLLKNHL S179-p
PTEN iso2 (human) RRYVYYYSYLLKNHL S352
PTEN (mouse) RRyVyyySYLLKNHL S179
PTEN (rat) RRYVYYYSYLLKNHL S179
Y180
RyVyyySYLLKNHLD
0 3
PTEN (human) RyVyyysyLLKNHLD Y180-p
PTEN iso2 (human) RYVYYYSYLLKNHLD Y353
PTEN (mouse) RyVyyySYLLKNHLD Y180
PTEN (rat) RYVYYYSYLLKNHLD Y180
K223
VVCQLKVKIYSSNSG
0 1
PTEN (human) VVCQLKVkIYSsNsG K223-ub
PTEN iso2 (human) VVCQLKVKIYSSNSG K396
PTEN (mouse) VVCQLKVKIYSSNSG K223
PTEN (rat) VVCQLKVKIYSSNSG K223
S227
LKVKIYSSNSGPTRR
0 1
PTEN (human) LKVkIYSsNsGPtRR S227-p
PTEN iso2 (human) LKVKIYSSNSGPTRR S400
PTEN (mouse) LKVKIYSSNSGPTRR S227
PTEN (rat) LKVKIYSSNSGPTRR S227
S229
VKIYSSNSGPTRRED
1 2
PTEN (human) VkIYSsNsGPtRRED S229-p
PTEN iso2 (human) VKIYSSNSGPTRRED S402
PTEN (mouse) VKIYSSNSGPTRRED S229
PTEN (rat) VKIYSSNSGPTRRED S229
T232
YSSNSGPTRREDKFM
1 2
PTEN (human) YSsNsGPtRREDKFM T232-p
PTEN iso2 (human) YSSNSGPTRREDKFM T405
PTEN (mouse) YSSNSGPTRREDKFM T232
PTEN (rat) YSSNSGPTRREDKLM T232
Y240
RREDKFMYFEFPQPL
4 1
PTEN (human) RREDKFMyFEFPQPL Y240-p
PTEN iso2 (human) RREDKFMYFEFPQPL Y413
PTEN (mouse) RREDKFMYFEFPQPL Y240
PTEN (rat) RREDKLMYFEFPQPL Y240
K254
LPVCGDIKVEFFHKQ
4 1
PTEN (human) LPVCGDIkVEFFHKQ K254-sm
PTEN iso2 (human) LPVCGDIKVEFFHKQ K427
PTEN (mouse) LPVCGDIKVEFFHKQ K254
PTEN (rat) LPVCGDIKVEFFHKQ K254
K266
HKQNKMLKKDKMFHF
4 0
PTEN (human) HKQNKMLkKDKMFHF K266-sm
PTEN iso2 (human) HKQNKMLKKDKMFHF K439
PTEN (mouse) HKQNKMLKKDKMFHF K266
PTEN (rat) HKQNKMLKKDKMFHF K266
K266
HKQNKMLKKDKMFHF
0 1
PTEN (human) HKQNKMLKKDKMFHF K266
PTEN iso2 (human) HKQNKMLKKDKMFHF K439
PTEN (mouse) HKQNKMLKKDKMFHF K266
PTEN (rat) HKQNKMLkKDKMFHF K266-ac
K289
GPEETSEKVENGsLC
4 0
PTEN (human) GPEETSEkVENGsLC K289-ub
PTEN iso2 (human) GPEETSEKVENGSLC K462
PTEN (mouse) GPEETSEKVENGsLC K289
PTEN (rat) GPEETSEKVENGSLC K289
K289
GPEETSEKVENGsLC
1 0
PTEN (human) GPEETSEkVENGsLC K289-sm
PTEN iso2 (human) GPEETSEKVENGSLC K462
PTEN (mouse) GPEETSEKVENGsLC K289
PTEN (rat) GPEETSEKVENGSLC K289
S294-p
SEKVENGsLCDQEID
0 7
PTEN (human) SEkVENGsLCDQEID S294-p
PTEN iso2 (human) SEKVENGSLCDQEID S467
PTEN (mouse) SEKVENGsLCDQEID S294-p
PTEN (rat) SEKVENGSLCDQEID S294
S302
LCDQEIDSICSIERA
0 1
PTEN (human) LCDQEIDsICSIERA S302-p
PTEN iso2 (human) LCDQEIDSICSIERA S475
PTEN (mouse) LCDQEIDSICSIERA S302
PTEN (rat) LCDQEIDSICSIERA S302
Y315
RADNDKEYLVLTLTK
4 1
PTEN (human) RADNDKEyLVLtLtK Y315-p
PTEN iso2 (human) RADNDKEYLVLTLTK Y488
PTEN (mouse) RADNDKEYLVLTLTK Y315
PTEN (rat) RADNDKEYLVLtLTK Y315
T319
DKEYLVLTLTKNDLD
1 1
PTEN (human) DKEyLVLtLtKNDLD T319-p
PTEN iso2 (human) DKEYLVLTLTKNDLD T492
PTEN (mouse) DKEYLVLTLTKNDLD T319
PTEN (rat) DKEYLVLtLTKNDLD T319-p
T321
EYLVLTLTKNDLDKA
1 0
PTEN (human) EyLVLtLtKNDLDKA T321-p
PTEN iso2 (human) EYLVLTLTKNDLDKA T494
PTEN (mouse) EYLVLTLTKNDLDKA T321
PTEN (rat) EYLVLtLTKNDLDKA T321
K332
LDKANKDKANRYFSP
0 1
PTEN (human) LDKANKDkANRyFSP K332-ac
PTEN iso2 (human) LDKANKDKANRYFSP K505
PTEN (mouse) LDKANKDKANRYFSP K332
PTEN (rat) LDKANKDKANRYFSP K332
Y336
NKDKANRYFSPNFKV
1 0
PTEN (human) NKDkANRyFSPNFKV Y336-p
PTEN iso2 (human) NKDKANRYFSPNFKV Y509
PTEN (mouse) NKDKANRYFSPNFKV Y336
PTEN (rat) NKDKANRYFSPNFKV Y336
S362
SNPEASSSTSVtPDV
1 0
PTEN (human) SNPEASSsTSVtPDV S362-p
PTEN iso2 (human) SNPEASSSTSVTPDV S535
PTEN (mouse) SNPEASSSTSVtPDV S362
PTEN (rat) SNPEASSSTSVTPDV S362
T366-p
ASSSTSVtPDVsDNE
Upstream
Downstream
6 4
Effects on Modified Protein
  • protein stabilization
Putative in vivo kinases:
  • GSK3B (mouse)
Treatment
  • lithium
PTEN (human) ASSsTSVtPDVsDNE T366-p
PTEN iso2 (human) ASSSTSVTPDVSDNE T539
PTEN (mouse) ASSSTSVtPDVsDNE T366-p
PTEN (rat) ASSSTSVTPDVSDNE T366
S370-p
TSVtPDVsDNEPDHY
Upstream
Downstream
11 7
Effects on Modified Protein
  • protein stabilization
Putative in vivo kinases:
  • CK2A1 (mouse)
Treatment
  • lithium
PTEN (human) TSVtPDVsDNEPDHy S370-p
PTEN iso2 (human) TSVTPDVSDNEPDHY S543
PTEN (mouse) TSVtPDVsDNEPDHY S370-p
PTEN (rat) TSVTPDVSDNEPDHY S370
Y377
sDNEPDHYRYsDttD
1 2
PTEN (human) sDNEPDHyRYsDttD Y377-p
PTEN iso2 (human) SDNEPDHYRYSDTTD Y550
PTEN (mouse) sDNEPDHYRYsDttD Y377
PTEN (rat) SDNEPDHYRYsDTtD Y377
S380-p
EPDHYRYsDttDsDP
Upstream
Downstream
31 0
PTEN (human)
S380-p
PTEN (mouse)
S380-p
PTEN (rat)
S380-p
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Regulatory protein:
  • Huntingtin (mouse)
Treatment
  • differentiation
  • H2O2
PTEN (human) EPDHyRYsDttDsDP S380-p
PTEN iso2 (human) EPDHYRYSDTTDSDP S553
PTEN (mouse) EPDHYRYsDttDsDP S380-p
PTEN (rat) EPDHYRYsDTtDsDP S380-p
T382-p
DHYRYsDttDsDPEN
Upstream
Downstream
18 2
PTEN (human)
T382-p
PTEN (mouse)
T382-p
PTEN (rat)
T382-p
Effects on Modified Protein
  • enzymatic activity, inhibited
Treatment
  • differentiation
PTEN (human) DHyRYsDttDsDPEN T382-p
PTEN iso2 (human) DHYRYSDTTDSDPEN T555
PTEN (mouse) DHYRYsDttDsDPEN T382-p
PTEN (rat) DHYRYsDTtDsDPEN T382
T383-p
HYRYsDttDsDPENE
Upstream
Downstream
19 3
PTEN (human)
T383-p
PTEN (mouse)
T383-p
PTEN (rat)
T383-p
Effects on Modified Protein
  • enzymatic activity, inhibited
Treatment
  • differentiation
PTEN (human) HyRYsDttDsDPENE T383-p
PTEN iso2 (human) HYRYSDTTDSDPENE T556
PTEN (mouse) HYRYsDttDsDPENE T383-p
PTEN (rat) HYRYsDTtDsDPENE T383-p
S385-p
RYsDttDsDPENEPF
Downstream
11 10
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
PTEN (human) RYsDttDsDPENEPF S385-p
PTEN iso2 (human) RYSDTTDSDPENEPF S558
PTEN (mouse) RYsDttDsDPENEPF S385-p
PTEN (rat) RYsDTtDsDPENEPF S385-p
S398-p
PFDEDQHsQITKV__
Upstream
Downstream
2 0
Effects on Modified Protein
  • methylation
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, inhibited
  • carcinogenesis, induced
Putative in vivo kinases:
  • ATM (mouse)
Regulatory protein:
  • ATR (human)
Treatment
  • etoposide
  • ionizing_radiation
  • KU-55933
  • MNNG
  • NVP-BKM120
  • siRNA
  • VE-821
PTEN (human) PFDEDQHtQItkV__ T398-p
PTEN iso2 (human) PFDEDQHTQITKV__ T571
PTEN (mouse) PFDEDQHsQITKV__ S398-p
PTEN (rat) PFDEDQHSQITKV__ S398
T401
EDQHsQITKV_____
1 0
PTEN (human) EDQHtQItkV_____ T401-p
PTEN iso2 (human) EDQHTQITKV_____ T574
PTEN (mouse) EDQHsQITKV_____ T401
PTEN (rat) EDQHSQITKV_____ T401
K402
DQHsQITKV______
1 0
PTEN (human) DQHtQItkV______ K402-ac
PTEN iso2 (human) DQHTQITKV______ K575
PTEN (mouse) DQHsQITKV______ K402
PTEN (rat) DQHSQITKV______ K402