Other Species / Isoforms
  RSK2 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S17
WQKMAVESPsDSAEN
0 2
RSK2 (human) WQKMAVEsPsDSAEN S17-p
RSK2 (mouse) WQKMAVESPsDSAEN S17
RSK2 (rat) WQKMAVESPSDSAEN S17
RSK2 (cow) WQKMAVESPSDSAEN S17
S19-p
KMAVESPsDSAENGQ
0 2
RSK2 (human) KMAVEsPsDSAENGQ S19-p
RSK2 (mouse) KMAVESPsDSAENGQ S19-p
RSK2 (rat) KMAVESPSDSAENGQ S19
RSK2 (cow) KMAVESPSDSAENGQ S19
K72
PSQFELLKVLGQGSF
0 2
RSK2 (human) PSQFELLkVLGQGsF K72-ub
RSK2 (mouse) PSQFELLKVLGQGSF K72
RSK2 (rat) PSQFELLKVLGQGSF K72
RSK2 (cow) PSQFELLKVLGQGSF K72
S78
LKVLGQGSFGKVFLV
0 3
RSK2 (human) LkVLGQGsFGkVFLV S78-p
RSK2 (mouse) LKVLGQGSFGKVFLV S78
RSK2 (rat) LKVLGQGSFGKVFLV S78
RSK2 (cow) LKVLGQGSFGKVFLV S78
K81
LGQGSFGKVFLVKKI
0 3
RSK2 (human) LGQGsFGkVFLVKKI K81-ac
RSK2 (mouse) LGQGSFGKVFLVKKI K81
RSK2 (rat) LGQGSFGKVFLVKKI K81
RSK2 (cow) LGQGSFGKVFLVKKI K81
K100
ARQLYAMKVLKKATL
0 1
RSK2 (human) ARQLYAMkVLkKATL K100-ac
RSK2 (mouse) ARQLYAMKVLKKATL K100
RSK2 (rat) ARQLYAMKVLKKATL K100
RSK2 (cow) ARQLYAMKVLKKATL K100
K103
LYAMKVLKKATLKVR
0 1
RSK2 (human) LYAMkVLkKATLKVR K103-ac
RSK2 (mouse) LYAMKVLKKATLKVR K103
RSK2 (rat) LYAMKVLKKATLKVR K103
RSK2 (cow) LYAMKVLKKATLKVR K103
R192-m1
HSLGIIYrDLKPENI
0 2
RSK2 (human) HSLGIIYRDLKPENI R192
RSK2 (mouse) HSLGIIYrDLKPENI R192-m1
RSK2 (rat) HSLGIIYRDLKPENI R192
RSK2 (cow) HSLGIIYRDLKPENI R192
S215-p
KLTDFGLsKESIDHE
0 2
RSK2 (human) KLTDFGLsKESIDHE S215-p
RSK2 (mouse) KLTDFGLsKESIDHE S215-p
RSK2 (rat) KLTDFGLSKESIDHE S215
RSK2 (cow) KLTDFGLSKESIDHE S215
Y226-p
IDHEKKAysFCGtVE
0 43
RSK2 (human) IDHEKKAysFCGtVE Y226-p
RSK2 (mouse) IDHEKKAysFCGtVE Y226-p
RSK2 (rat) IDHEKKAYsFCGTVE Y226
RSK2 (cow) IDHEKKAYSFCGTVE Y226
S227-p
DHEKKAysFCGtVEy
Upstream
Downstream
12 184
RSK2 (human)
S227-p
RSK2 (mouse)
S227-p
RSK2 (rat)
S227-p
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • ERK2 (human)
  • MAPKAPK2 (human)
  • PDK1 (human)
  • PDK1 (mouse)
Putative in vivo kinases:
  • PDK1 (human)
Treatment
  • BIRB-0796
  • contextual fear conditioning
  • EGF
  • LPS
  • PD184352
  • PDGF
  • SB203580
RSK2 (human) DHEKKAysFCGtVEy S227-p
RSK2 (mouse) DHEKKAysFCGtVEy S227-p
RSK2 (rat) DHEKKAYsFCGTVEY S227-p
RSK2 (cow) DHEKKAYSFCGTVEY S227
T231-p
KAysFCGtVEyMAPE
0 75
RSK2 (human) KAysFCGtVEyMAPE T231-p
RSK2 (mouse) KAysFCGtVEyMAPE T231-p
RSK2 (rat) KAYsFCGTVEYMAPE T231
RSK2 (cow) KAYSFCGTVEYMAPE T231
Y234-p
sFCGtVEyMAPEVVN
0 18
RSK2 (human) sFCGtVEyMAPEVVN Y234-p
RSK2 (mouse) sFCGtVEyMAPEVVN Y234-p
RSK2 (rat) sFCGTVEYMAPEVVN Y234
RSK2 (cow) SFCGTVEYMAPEVVN Y234
K274-ub
PFQGKDRkETMTMIL
0 3
RSK2 (human) PFQGKDRkETMtMIL K274-ub
RSK2 (mouse) PFQGKDRkETMTMIL K274-ub
RSK2 (rat) PFQGKDRKETMTMIL K274
RSK2 (cow) PFQGKDRKETMTMIL K274
T278
KDRkETMTMILkAkL
0 1
RSK2 (human) KDRkETMtMILKAKL T278-p
RSK2 (mouse) KDRkETMTMILkAkL T278
RSK2 (rat) KDRKETMTMILKAKL T278
RSK2 (cow) KDRKETMTMILKAKL T278
K282-ub
ETMTMILkAkLGMPQ
0 2
RSK2 (human) ETMtMILKAKLGMPQ K282
RSK2 (mouse) ETMTMILkAkLGMPQ K282-ub
RSK2 (rat) ETMTMILKAKLGMPQ K282
RSK2 (cow) ETMTMILKAKLGMPQ K282
K284-ac
MTMILkAkLGMPQFL
0 1
RSK2 (human) MtMILKAKLGMPQFL K284
RSK2 (mouse) MTMILkAkLGMPQFL K284-ac
RSK2 (rat) MTMILKAKLGMPQFL K284
RSK2 (cow) MTMILKAKLGMPQFL K284
K322
PDGVEEIKRHSFFST
0 7
RSK2 (human) PDGVEEIkRHSFFST K322-ub
RSK2 (mouse) PDGVEEIKRHSFFST K322
RSK2 (rat) PDGVEEIKRHSFFST K322
RSK2 (cow) PDGVEEIKRHSFFST K322
T348-p
HPPFKPAtGRPEDTF
0 1
RSK2 (human) HPPFKPATGRPEDTF T348
RSK2 (mouse) HPPFKPAtGRPEDTF T348-p
RSK2 (rat) HPPFKPATGRPEDTF T348
RSK2 (cow) HPPFKPATGRPEDTF T348
Y356
GRPEDTFYFDPEFTA
0 4
RSK2 (human) GRPEDTFyFDPEFtA Y356-p
RSK2 (mouse) GRPEDTFYFDPEFTA Y356
RSK2 (rat) GRPEDTFYFDPEFTA Y356
RSK2 (cow) GRPEDTFYFDPEFTA Y356
T362
FYFDPEFTAKtPKDs
0 3
RSK2 (human) FyFDPEFtAKtPKDs T362-p
RSK2 (mouse) FYFDPEFTAKtPKDs T362
RSK2 (rat) FYFDPEFTAKtPKDs T362
RSK2 (cow) FYFDPEFTAKTPKDS T362
T365-p
DPEFTAKtPKDsPGI
Upstream
Downstream
6 47
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • BIRB-0796
  • EGF
  • insulin
  • LPS
  • PD184352
  • SB203580
RSK2 (human) DPEFtAKtPKDsPGI T365-p
RSK2 (mouse) DPEFTAKtPKDsPGI T365-p
RSK2 (rat) DPEFTAKtPKDsPGI T365-p
RSK2 (cow) DPEFTAKTPKDSPGI T365
S369-p
TAKtPKDsPGIPPsA
Upstream
Downstream
10 65
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • PDK1 (mouse)
Regulatory protein:
  • FLT3 (mouse)
Treatment
  • BIRB-0796
  • EGF
  • insulin
  • LPS
  • PD184352
  • SB203580
RSK2 (human) tAKtPKDsPGIPPsA S369-p
RSK2 (mouse) TAKtPKDsPGIPPsA S369-p
RSK2 (rat) TAKtPKDsPGIPPsA S369-p
RSK2 (cow) TAKTPKDSPGIPPSA S369
S375-p
DsPGIPPsANAHQLF
Upstream
0 20
Treatment
  • insulin
RSK2 (human) DsPGIPPsANAHQLF S375-p
RSK2 (mouse) DsPGIPPsANAHQLF S375-p
RSK2 (rat) DsPGIPPsANAHQLF S375-p
RSK2 (cow) DSPGIPPSANAHQLF S375
S386-p
HQLFRGFsFVAITSD
Upstream
Downstream
11 75
RSK2 (human)
S386-p
RSK2 (mouse)
S386-p
RSK2 (rat)
S386-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Kinase, in vitro:
  • ERK1 (mouse)
  • ERK2 (human)
  • MAPKAPK2 (human)
  • PDK1 (human)
  • PDK1 (mouse)
Putative in vivo kinases:
  • RSK2 (mouse)
Regulatory protein:
  • MAPKAPK2 (mouse)
  • MAPKAPK3 (mouse)
  • MEK1 (human)
Treatment
  • anisomycin
  • BIRB-0796
  • EGF
  • LPS
  • Pam3CSK4
  • PD184352
  • phorbol_ester
  • SB203347
  • SB203580
  • TNF
RSK2 (human) HQLFRGFsFVAItsD S386-p
RSK2 (mouse) HQLFRGFsFVAITSD S386-p
RSK2 (rat) HQLFRGFSFVAITSD S386
RSK2 (cow) HQLFRGFSFVAITSD S386
T391
GFsFVAITSDDESQA
0 1
RSK2 (human) GFsFVAItsDDEsQA T391-p
RSK2 (mouse) GFsFVAITSDDESQA T391
RSK2 (rat) GFSFVAITSDDESQA T391
RSK2 (cow) GFSFVAITSDDESQA T391
S392
FsFVAITSDDESQAM
0 3
RSK2 (human) FsFVAItsDDEsQAM S392-p
RSK2 (mouse) FsFVAITSDDESQAM S392
RSK2 (rat) FSFVAITSDDESQAM S392
RSK2 (cow) FSFVAITSDDESQAM S392
S396
AITSDDESQAMQTVG
0 2
RSK2 (human) AItsDDEsQAMQTVG S396-p
RSK2 (mouse) AITSDDESQAMQTVG S396
RSK2 (rat) AITSDDESQAMQTVG S396
RSK2 (cow) AITSDDESQAMQTVG S396
S415-p
VQQLHRNsIQFTDGY
Upstream
0 27
Treatment
  • insulin
  • MK-2206
RSK2 (human) VQQLHRNsIQFTDGY S415-p
RSK2 (mouse) VQQLHRNsIQFTDGY S415-p
RSK2 (rat) VQQLHRNsIQFTDGY S415-p
RSK2 (cow) VQQLHRNSIQFTDGY S415
Y470-p
EIEILLRyGQHPNII
1 6
RSK2 (human) EIEILLRyGQHPNII Y470-p
RSK2 (mouse) EIEILLRyGQHPNII Y470-p
RSK2 (rat) EIEILLRYGQHPNII Y470
RSK2 (cow) EIEILLRYGQHPNII Y470
T478-p
GQHPNIItLKDVyDD
0 2
RSK2 (human) GQHPNIItLKDVyDD T478-p
RSK2 (mouse) GQHPNIItLKDVyDD T478-p
RSK2 (rat) GQHPNIITLKDVYDD T478
RSK2 (cow) GQHPNIITLKDVYDD T478
Y483-p
IItLKDVyDDGKyVy
1 6
RSK2 (human) IItLKDVyDDGKyVY Y483-p
RSK2 (mouse) IItLKDVyDDGKyVy Y483-p
RSK2 (rat) IITLKDVYDDGKYVY Y483
RSK2 (cow) IITLKDVYDDGKYVY Y483
Y488-p
DVyDDGKyVyVVTEL
2 16
RSK2 (human) DVyDDGKyVYVVTEL Y488-p
RSK2 (mouse) DVyDDGKyVyVVTEL Y488-p
RSK2 (rat) DVYDDGKYVYVVTEL Y488
RSK2 (cow) DVYDDGKYVYVVTEL Y488
Y490-p
yDDGKyVyVVTELMK
0 1
RSK2 (human) yDDGKyVYVVTELMK Y490
RSK2 (mouse) yDDGKyVyVVTELMK Y490-p
RSK2 (rat) YDDGKYVYVVTELMK Y490
RSK2 (cow) YDDGKYVYVVTELMK Y490
S517
FFSEREASAVLFTIT
0 1
RSK2 (human) FFSEREAsAVLFTIT S517-p
RSK2 (mouse) FFSEREASAVLFTIT S517
RSK2 (rat) FFSEREASAVLFTIT S517
RSK2 (cow) FFSEREASAVLFTIT S517
Y529-p
TITKTVEyLHAQGVV
4 5
RSK2 (human) TITKTVEyLHAQGVV Y529-p
RSK2 (mouse) TITKTVEyLHAQGVV Y529-p
RSK2 (rat) TITKTVEYLHTQGVV Y529
RSK2 (cow) TITKTVEYLHAQGVV Y529
S556
DESGNPESIRICDFG
0 1
RSK2 (human) DESGNPEsIRICDFG S556-p
RSK2 (mouse) DESGNPESIRICDFG S556
RSK2 (rat) DESGNPESIRICDFG S556
RSK2 (cow) DESGNPESIRICDFG S556
K566-ub
ICDFGFAkQLRAENG
0 4
RSK2 (human) ICDFGFAkQLRAENG K566-ub
RSK2 (mouse) ICDFGFAkQLRAENG K566-ub
RSK2 (rat) ICDFGFAKQLRAENG K566
RSK2 (cow) ICDFGFAKQLRAENG K566
T577-p
AENGLLMtPCYtANF
Upstream
Downstream
9 188
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • ERK2 (human)
  • PDK1 (human)
  • PDK1 (mouse)
Regulatory protein:
  • MAPKAPK2 (mouse)
  • MAPKAPK3 (mouse)
Treatment
  • BIRB-0796
  • EGF
  • IL-33
  • LPS
  • PD184352
  • SB203580
RSK2 (human) AENGLLMtPCytANF T577-p
RSK2 (mouse) AENGLLMtPCYtANF T577-p
RSK2 (rat) AENGLLMTPCYTANF T577
RSK2 (cow) AENGLLMTPCYTANF T577
Y580
GLLMtPCYtANFVAP
1 85
RSK2 (human) GLLMtPCytANFVAP Y580-p
RSK2 (mouse) GLLMtPCYtANFVAP Y580
RSK2 (rat) GLLMTPCYTANFVAP Y580
RSK2 (cow) GLLMTPCYTANFVAP Y580
T581-p
LLMtPCYtANFVAPE
0 27
RSK2 (human) LLMtPCytANFVAPE T581-p
RSK2 (mouse) LLMtPCYtANFVAPE T581-p
RSK2 (rat) LLMTPCYTANFVAPE T581
RSK2 (cow) LLMTPCYTANFVAPE T581
Y644
KFSLSGGYWNSVSDT
1 3
RSK2 (human) KFSLSGGyWNSVSDT Y644-p
RSK2 (mouse) KFSLSGGYWNSVSDT Y644
RSK2 (rat) KFSLSGGYWNSVSDT Y644
RSK2 (cow) KFSLSGGYWNSVSDT Y644
Y688
HWDQLPQYQLNRQDA
0 20
RSK2 (human) HWDQLPQyQLNRQDA Y688-p
RSK2 (mouse) HWDQLPQYQLNRQDA Y688
RSK2 (rat) HWDQLPQYQLNRQDA Y688
RSK2 (cow) HWDQLPQYQLNRQDA Y688
T706
VKGAMAATYSALNRN
0 1
RSK2 (human) VKGAMAAtysALNRN T706-p
RSK2 (mouse) VKGAMAATYSALNRN T706
RSK2 (rat) VKGAMAATYSALNRN T706
RSK2 (cow) VKGAMAATYSALNRN T706
Y707
KGAMAATYSALNRNQ
2 86
RSK2 (human) KGAMAAtysALNRNQ Y707-p
RSK2 (mouse) KGAMAATYSALNRNQ Y707
RSK2 (rat) KGAMAATYSALNRNQ Y707
RSK2 (cow) KGAMAATYSALNRNQ Y707
S708
GAMAATYSALNRNQs
0 1
RSK2 (human) GAMAAtysALNRNQs S708-p
RSK2 (mouse) GAMAATYSALNRNQs S708
RSK2 (rat) GAMAATYSALNRNQs S708
RSK2 (cow) GAMAATYSALNRNQs S708
S715-p
SALNRNQsPVLEPVG
Upstream
0 76
Treatment
  • insulin
  • LY294002
RSK2 (human) sALNRNQsPVLEPVG S715-p
RSK2 (mouse) SALNRNQsPVLEPVG S715-p
RSK2 (rat) SALNRNQsPVLEPVG S715-p
RSK2 (cow) SALNRNQsPVLEPVG S715-p
R723
PVLEPVGRSTLAQRR
0 2
RSK2 (human) PVLEPVGrSTLAQRR R723-m1
RSK2 (mouse) PVLEPVGRSTLAQRR R723
RSK2 (rat) PVLEPVGRSTLAQRR R723
RSK2 (cow) PVLEPVGRSTLAQRR R723
S737-p
RGIKKITsTAL____
Upstream
0 4
Treatment
  • NAG-thiazoline
  • okadaic_acid
  • PUGNAc
RSK2 (human) RGIKKITsTAL____ S737-p
RSK2 (mouse) RGIKKITsTAL____ S737-p
RSK2 (rat) RGIKKITSTAL____ S737
RSK2 (cow) RGIKKITSTAL____ S737