Other Species / Isoforms
  S6 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K2
______MKLNISFPA
0 1
S6 (human) ______MkLNIsFPA K2-m1
S6 (mouse) ______MKLNISFPA K2
S6 (rat) ______MKLNISFPA K2
S6 (fruit fly) ______MKLNVSYPA K2
S6 (cow) ______MKLNISFPA K2
S6
__MKLNISFPATGCQ
0 5
S6 (human) __MkLNIsFPATGCQ S6-p
S6 (mouse) __MKLNISFPATGCQ S6
S6 (rat) __MKLNISFPATGCQ S6
S6 (fruit fly) __MKLNVSYPATGCQ S6
S6 (cow) __MKLNISFPATGCQ S6
K14-ub
FPATGCQkLIEVDDE
0 8
S6 (human) FPATGCQkLIEVDDE K14-ub
S6 (mouse) FPATGCQkLIEVDDE K14-ub
S6 (rat) FPATGCQKLIEVDDE K14
S6 (fruit fly) YPATGCQKLFEVVDE K14
S6 (cow) FPATGCQKLIEVDDE K14
K14
FPATGCQKLIEVDDE
0 3
S6 (human) FPATGCQkLIEVDDE K14-ac
S6 (mouse) FPATGCQKLIEVDDE K14
S6 (rat) FPATGCQKLIEVDDE K14
S6 (fruit fly) YPATGCQKLFEVVDE K14
S6 (cow) FPATGCQKLIEVDDE K14
R22
LIEVDDERKLRTFYE
0 1
S6 (human) LIEVDDErkLRTFyE R22-m1
S6 (mouse) LIEVDDERKLRTFYE R22
S6 (rat) LIEVDDERKLRTFYE R22
S6 (fruit fly) LFEVVDEHKLRVFYE H22
S6 (cow) LIEVDDERKLRTFYE R22
K23
IEVDDERKLRTFYEK
0 1
S6 (human) IEVDDErkLRTFyEk K23-ub
S6 (mouse) IEVDDERKLRTFYEK K23
S6 (rat) IEVDDERKLRTFYEk K23
S6 (fruit fly) FEVVDEHKLRVFYEK K23
S6 (cow) IEVDDERKLRTFYEK K23
Y28
ERKLRTFYEKRMATE
0 1
S6 (human) ErkLRTFyEkRMATE Y28-p
S6 (mouse) ERKLRTFYEKRMATE Y28
S6 (rat) ERKLRTFYEkRMATE Y28
S6 (fruit fly) EHKLRVFYEKRMGQV Y28
S6 (cow) ERKLRTFYEKRMATE Y28
K30
KLRTFYEKRMATEVA
0 2
S6 (human) kLRTFyEkRMATEVA K30-ac
S6 (mouse) KLRTFYEKRMATEVA K30
S6 (rat) KLRTFYEkRMATEVA K30-ac
S6 (fruit fly) KLRVFYEKRMGQVVE K30
S6 (cow) KLRTFYEKRMATEVA K30
K30
KLRTFYEKRMATEVA
0 1
S6 (human) kLRTFyEkRMATEVA K30-sc
S6 (mouse) KLRTFYEKRMATEVA K30
S6 (rat) KLRTFYEKRMATEVA K30
S6 (fruit fly) KLRVFYEKRMGQVVE K30
S6 (cow) KLRTFYEKRMATEVA K30
K30
KLRTFYEKRMATEVA
0 1
S6 (human) kLRTFyEkRMATEVA K30-ub
S6 (mouse) KLRTFYEKRMATEVA K30
S6 (rat) KLRTFYEKRMATEVA K30
S6 (fruit fly) KLRVFYEKRMGQVVE K30
S6 (cow) KLRTFYEKRMATEVA K30
K46-sc
DALGEEWkGYVVRIS
0 1
S6 (human) DALGEEWKGyVVRIs K46
S6 (mouse) DALGEEWkGYVVRIS K46-sc
S6 (rat) DALGEEWKGYVVRIS K46
S6 (fruit fly) DILGDEWKGYQLRIA K46
S6 (cow) DALGEEWKGYVVRIS K46
K46-ac
DALGEEWkGYVVRIS
0 1
S6 (human) DALGEEWKGyVVRIs K46
S6 (mouse) DALGEEWkGYVVRIS K46-ac
S6 (rat) DALGEEWKGYVVRIS K46
S6 (fruit fly) DILGDEWKGYQLRIA K46
S6 (cow) DALGEEWKGYVVRIS K46
K46
DALGEEWKGYVVRIS
0 1
S6 (human) DALGEEWkGyVVRIs K46-ub
S6 (mouse) DALGEEWKGYVVRIS K46
S6 (rat) DALGEEWKGYVVRIS K46
S6 (fruit fly) DILGDEWKGYQLRIA K46
S6 (cow) DALGEEWKGYVVRIS K46
Y48
LGEEWkGYVVRISGG
0 1
S6 (human) LGEEWkGyVVRIsGG Y48-p
S6 (mouse) LGEEWkGYVVRISGG Y48
S6 (rat) LGEEWKGYVVRISGG Y48
S6 (fruit fly) LGDEWKGYQLRIAGG Y48
S6 (cow) LGEEWKGYVVRISGG Y48
S53
kGYVVRISGGNDkQG
0 1
S6 (human) kGyVVRIsGGNDkQG S53-p
S6 (mouse) kGYVVRISGGNDkQG S53
S6 (rat) KGYVVRISGGNDKQG S53
S6 (fruit fly) KGYQLRIAGGNDKQG A53
S6 (cow) KGYVVRISGGNDKQG S53
K58-ac
RISGGNDkQGFPMKQ
0 2
S6 (human) RIsGGNDKQGFPMkQ K58
S6 (mouse) RISGGNDkQGFPMKQ K58-ac
S6 (rat) RISGGNDKQGFPMkQ K58
S6 (fruit fly) RIAGGNDKQGFPMKQ K58
S6 (cow) RISGGNDKQGFPMKQ K58
K58-ub
RISGGNDkQGFPMKQ
0 10
S6 (human) RIsGGNDkQGFPMkQ K58-ub
S6 (mouse) RISGGNDkQGFPMKQ K58-ub
S6 (rat) RISGGNDKQGFPMkQ K58
S6 (fruit fly) RIAGGNDKQGFPMKQ K58
S6 (cow) RISGGNDKQGFPMKQ K58
K64
DkQGFPMKQGVLTHG
0 4
S6 (human) DkQGFPMkQGVLtHG K64-ub
S6 (mouse) DkQGFPMKQGVLTHG K64
S6 (rat) DKQGFPMKQGVLTHG K64
S6 (fruit fly) DKQGFPMKQGVLTHG K64
S6 (cow) DKQGFPMKQGVLTHG K64
K64
DkQGFPMKQGVLTHG
0 1
S6 (human) DkQGFPMKQGVLtHG K64
S6 (mouse) DkQGFPMKQGVLTHG K64
S6 (rat) DKQGFPMkQGVLTHG K64-ac
S6 (fruit fly) DKQGFPMKQGVLTHG K64
S6 (cow) DKQGFPMKQGVLTHG K64
T69
PMKQGVLTHGRVRLL
0 2
S6 (human) PMkQGVLtHGRVRLL T69-p
S6 (mouse) PMKQGVLTHGRVRLL T69
S6 (rat) PMkQGVLTHGRVRLL T69
S6 (fruit fly) PMKQGVLTHGRVRLL T69
S6 (cow) PMKQGVLTHGRVRLL T69
S78
GRVRLLLSKGHSCYR
0 3
S6 (human) GRVRLLLskGHsCYR S78-p
S6 (mouse) GRVRLLLSKGHSCYR S78
S6 (rat) GRVRLLLSKGHSCYR S78
S6 (fruit fly) GRVRLLLKKGHSCYR K78
S6 (cow) GRVRLLLSKGHSCYR S78
K79
RVRLLLSKGHSCYRP
0 2
S6 (human) RVRLLLskGHsCYRP K79-ub
S6 (mouse) RVRLLLSKGHSCYRP K79
S6 (rat) RVRLLLSKGHSCYRP K79
S6 (fruit fly) RVRLLLKKGHSCYRP K79
S6 (cow) RVRLLLSKGHSCYRP K79
K79
RVRLLLSKGHSCYRP
0 1
S6 (human) RVRLLLskGHsCYRP K79-ac
S6 (mouse) RVRLLLSKGHSCYRP K79
S6 (rat) RVRLLLSKGHSCYRP K79
S6 (fruit fly) RVRLLLKKGHSCYRP K79
S6 (cow) RVRLLLSKGHSCYRP K79
S82
LLLSKGHSCYRPRRT
0 1
S6 (human) LLLskGHsCYRPRRT S82-p
S6 (mouse) LLLSKGHSCYRPRRT S82
S6 (rat) LLLSKGHSCYRPRRT S82
S6 (fruit fly) LLLKKGHSCYRPRRT S82
S6 (cow) LLLSKGHSCYRPRRT S82
K116-ub
LNLVIVKkGEkDIPG
0 2
S6 (human) LNLVIVKkGEkDIPG K116-ub
S6 (mouse) LNLVIVKkGEkDIPG K116-ub
S6 (rat) LNLVIVKKGEKDIPG K116
S6 (fruit fly) LALVVLKKGEKDIPG K116
S6 (cow) LNLVIVKKGEKDIPG K116
K119-ub
VIVKkGEkDIPGLTD
0 2
S6 (human) VIVKkGEkDIPGLTD K119-ub
S6 (mouse) VIVKkGEkDIPGLTD K119-ub
S6 (rat) VIVKKGEKDIPGLTD K119
S6 (fruit fly) VVLKKGEKDIPGLTD K119
S6 (cow) VIVKKGEKDIPGLTD K119
T128-p
IPGLTDTtVPRRLGP
0 2
S6 (human) IPGLTDTtVPRRLGP T128-p
S6 (mouse) IPGLTDTtVPRRLGP T128-p
S6 (rat) IPGLTDTTVPRRLGP T128
S6 (fruit fly) IPGLTDTTIPRRLGP T128
S6 (cow) IPGLTDTTVPRRLGP T128
K143-ub
KRASRIRkLFNLskE
0 5
S6 (human) KRASRIRkLFNLskE K143-ub
S6 (mouse) KRASRIRkLFNLskE K143-ub
S6 (rat) KRASRIRKLFNLskE K143
S6 (fruit fly) KRASKIRKLYNLSKE K143
S6 (cow) KRASRIRKLFNLSKE K143
K143
KRASRIRKLFNLskE
0 2
S6 (human) KRASRIRkLFNLskE K143-ac
S6 (mouse) KRASRIRKLFNLskE K143
S6 (rat) KRASRIRKLFNLskE K143
S6 (fruit fly) KRASKIRKLYNLSKE K143
S6 (cow) KRASRIRKLFNLSKE K143
S148-p
IRkLFNLskEDDVRQ
0 11
S6 (human) IRkLFNLskEDDVrQ S148-p
S6 (mouse) IRkLFNLskEDDVRQ S148-p
S6 (rat) IRKLFNLskEDDVRQ S148-p
S6 (fruit fly) IRKLYNLSKEDDVRR S148
S6 (cow) IRKLFNLSKEDDVRQ S148
K149-ub
RkLFNLskEDDVRQY
0 10
S6 (human) RkLFNLskEDDVrQY K149-ub
S6 (mouse) RkLFNLskEDDVRQY K149-ub
S6 (rat) RKLFNLsKEDDVRQY K149
S6 (fruit fly) RKLYNLSKEDDVRRF K149
S6 (cow) RKLFNLSKEDDVRQY K149
K149-sc
RkLFNLskEDDVRQY
0 1
S6 (human) RkLFNLskEDDVrQY K149-sc
S6 (mouse) RkLFNLskEDDVRQY K149-sc
S6 (rat) RKLFNLsKEDDVRQY K149
S6 (fruit fly) RKLYNLSKEDDVRRF K149
S6 (cow) RKLFNLSKEDDVRQY K149
K149
RkLFNLsKEDDVRQY
0 1
S6 (human) RkLFNLsKEDDVrQY K149
S6 (mouse) RkLFNLsKEDDVRQY K149
S6 (rat) RKLFNLskEDDVRQY K149-ac
S6 (fruit fly) RKLYNLSKEDDVRRF K149
S6 (cow) RKLFNLSKEDDVRQY K149
R154
LskEDDVRQYVVRKP
0 1
S6 (human) LskEDDVrQYVVRkP R154-m1
S6 (mouse) LskEDDVRQYVVRKP R154
S6 (rat) LskEDDVRQYVVRKP R154
S6 (fruit fly) LSKEDDVRRFVVRRP R154
S6 (cow) LSKEDDVRQYVVRKP R154
K160
VRQYVVRKPLNKEGK
0 1
S6 (human) VrQYVVRkPLNKEGK K160-ub
S6 (mouse) VRQYVVRKPLNKEGK K160
S6 (rat) VRQYVVRKPLNKEGK K160
S6 (fruit fly) VRRFVVRRPLPAKDN R160
S6 (cow) VRQYVVRKPLNKDGK K160
T181
PKIQRLVTPRVLQHK
0 2
S6 (human) PKIQRLVtPRVLQHK T181-p
S6 (mouse) PKIQRLVTPRVLQHK T181
S6 (rat) PKIQRLVTPRVLQHK T181
S6 (fruit fly) PKIQRLITPVVLQRK T182
S6 (cow) PKIQRLVTPRVLQHK T181
K203-ac
KQRTKKNkEEAAEyA
Upstream
0 3
Treatment
  • gut microbiota
S6 (human) KQRTKKNKEEAAEyA K203
S6 (mouse) KQRTKKNkEEAAEyA K203-ac
S6 (rat) KQRTKKNkEEAAEYA K203-ac
S6 (fruit fly) KKRQIASKEASADYA K204
S6 (cow) KQRTKKNKEEAAEYA K203
K203-ub
KQRTKKNkEEAAEyA
0 7
S6 (human) KQRTKKNkEEAAEyA K203-ub
S6 (mouse) KQRTKKNkEEAAEyA K203-ub
S6 (rat) KQRTKKNKEEAAEYA K203
S6 (fruit fly) KKRQIASKEASADYA K204
S6 (cow) KQRTKKNKEEAAEYA K203
K203-sc
KQRTKKNkEEAAEyA
0 1
S6 (human) KQRTKKNKEEAAEyA K203
S6 (mouse) KQRTKKNkEEAAEyA K203-sc
S6 (rat) KQRTKKNKEEAAEYA K203
S6 (fruit fly) KKRQIASKEASADYA K204
S6 (cow) KQRTKKNKEEAAEYA K203
Y209-p
NkEEAAEyAkLLAKR
Upstream
0 20
Treatment
  • IL-33
S6 (human) NkEEAAEyAkLLAKR Y209-p
S6 (mouse) NkEEAAEyAkLLAKR Y209-p
S6 (rat) NkEEAAEYAkLLAKR Y209
S6 (fruit fly) SKEASADYAKLLVQR Y210
S6 (cow) NKEEAAEYAKLLAKR Y209
K211-ac
EEAAEyAkLLAKRMK
Upstream
0 5
Treatment
  • gut microbiota
S6 (human) EEAAEyAkLLAKRMk K211-ac
S6 (mouse) EEAAEyAkLLAKRMK K211-ac
S6 (rat) EEAAEYAkLLAKRMK K211-ac
S6 (fruit fly) EASADYAKLLVQRKK K212
S6 (cow) EEAAEYAKLLAKRMK K211
K211-ub
EEAAEyAkLLAKRMK
0 10
S6 (human) EEAAEyAkLLAKRMk K211-ub
S6 (mouse) EEAAEyAkLLAKRMK K211-ub
S6 (rat) EEAAEYAKLLAKRMK K211
S6 (fruit fly) EASADYAKLLVQRKK K212
S6 (cow) EEAAEYAKLLAKRMK K211
K218
kLLAKRMKEAKEKRQ
0 1
S6 (human) kLLAKRMkEAKEKRQ K218-ac
S6 (mouse) kLLAKRMKEAKEKRQ K218
S6 (rat) kLLAKRMKEAKEKRQ K218
S6 (fruit fly) KLLVQRKKESKAKRE K219
S6 (cow) KLLAKRMKEAKEKRQ K218
S235-p
IAKRRRLssLRAsts
Upstream
Downstream
265 1028
S6 (human)
S235-p
S6 (mouse)
S235-p
S6 (rat)
S235-p
S6 (cow)
S235-p
Effects on Biological Processes:
  • autophagy, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell growth, induced
  • neural plasticity
  • signaling pathway regulation
  • transcription, inhibited
  • translation, induced
Kinase, in vitro:
  • p70S6K (mouse)
Putative in vivo kinases:
  • mTOR (mouse)
  • p70S6K (mouse)
  • P70S6KB (mouse)
  • Pim1 (human)
  • RSK2 (human)
Regulatory protein:
  • ADRB1 (mouse)
  • AMPKA1 (human)
  • AMPKA1 (mouse)
  • AMPKA2 (mouse)
  • CDC42 (mouse)
  • DMP1 (human)
  • FMR1 (mouse)
  • Fyn (mouse)
  • GAB2 (mouse)
  • IGBP1 (mouse)
  • IGF1R (mouse)
  • IRS1 (human)
  • JAK2 (human)
  • KRas (mouse)
  • leptin (mouse)
  • LIN28A (mouse)
  • LIN28B (mouse)
  • LKB1 (human)
  • LKB1 (mouse)
  • mAChR M3 (human)
  • MC4R (human)
  • P2Y6 (human)
  • p53 (human)
  • p70S6K (mouse)
  • PAK4 (mouse)
  • PDK1 (human)
  • PDK1 (mouse)
  • PHLPP (human)
  • PIK3CA (mouse)
  • PTEN (human)
  • PTEN (mouse)
  • RAG1 (mouse)
  • Raptor (human)
  • Raptor (mouse)
  • RHEB (human)
  • RICTOR (mouse)
  • S6 (human)
  • syndecan-4 (mouse)
  • TBC1D1 (mouse)
  • TCF7 (human)
  • TDGF1 (mouse)
  • TNFRSF18 (human)
  • TRAF3 (human)
  • TRIP8 (mouse)
  • TSC1 (human)
  • TSC1 (mouse)
  • TSC2 (mouse)
  • UCN2 (human)
  • USP1 (human)
  • Vimentin (human)
  • ZFP91 (human)
Treatment
  • 17-beta-estradiol
  • 4-HT
  • 991
  • A-443654
  • acadesine
  • Akt-I-1
  • Akt_inhibitor_VIII
  • AMDE-1
  • amino_acids
  • antibody
  • antigenic stimulation
  • B7
  • bacterial infection
  • bicuculline
  • BMS-536924
  • BSO
  • butyrate
  • calorie_restriction
  • CB839
  • CGRP
  • CNO
  • colforsin
  • culturing_of_cells
  • dactolisib
  • EGF
  • Epo
  • fasting
  • fedratinib
  • fructose
  • glucose
  • glycine
  • H-89
  • HC-5404
  • high-fat diet
  • IBMX
  • idelalisib
  • IGF-1
  • IL-11
  • IL-12
  • IL-15
  • IL-3
  • IL-33
  • imatinib
  • injury
  • insulin
  • ipatasertib
  • L-glutamine_withdrawal
  • LIF withdrawal
  • linsitinib
  • LPS
  • LTV-1
  • LY294002
  • meal feeding
  • miRNA
  • MK-2206
  • Mn(2+)
  • MPA
  • MRTX1133
  • NBD_peptide
  • Necrostatin-1
  • nitric_oxide
  • norepinephrine
  • NP68
  • NVP-AEW541
  • NVP-BKM120
  • orexin
  • OSMI-1
  • palbociclib
  • palmitate
  • PD184352
  • PP1
  • PP2
  • pressure
  • Proopiomelanocortin
  • RAD001
  • RAMH
  • rapamycin
  • refeeding
  • S961
  • SEL24-B489
  • serum
  • serum_starvation
  • SF1670
  • siRNA
  • sleep deprivation
  • starvation_medium
  • TEVs
  • TGF-beta
  • TNF
  • Torin1
  • Trametinib
  • tunicamycin
  • U0126
  • wortmannin
  • XL-147
  • Z-VAD-FMK
S6 (human) IAKRRRLssLRAsts S235-p
S6 (mouse) IAKRRRLssLRAsts S235-p
S6 (rat) IAKRRRLssLRAsts S235-p
S6 (fruit fly) EAKRRRSASIRESKS A234
S6 (cow) IAKRRRLssLRAsTS S235-p
S236-p
AKRRRLssLRAstsK
Upstream
Downstream
258 1191
S6 (human)
S236-p
S6 (mouse)
S236-p
S6 (rat)
S236-p
S6 (cow)
S236-p
Effects on Biological Processes:
  • autophagy, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell growth, induced
  • neural plasticity
  • signaling pathway regulation
  • transcription, inhibited
  • translation, induced
Kinase, in vitro:
  • p70S6K (mouse)
Putative in vivo kinases:
  • Akt1 (mouse)
  • mTOR (mouse)
  • p70S6K (mouse)
  • P70S6KB (mouse)
  • Pim1 (human)
  • RSK2 (human)
Regulatory protein:
  • ADRB1 (mouse)
  • AMPKA1 (human)
  • AMPKA1 (mouse)
  • AMPKA2 (mouse)
  • CDC42 (mouse)
  • DDIT4 (mouse)
  • DMP1 (human)
  • FMR1 (mouse)
  • Fyn (mouse)
  • GAB2 (mouse)
  • Huntingtin (mouse)
  • IGBP1 (mouse)
  • IGF1R (mouse)
  • IRS1 (human)
  • JAK2 (human)
  • KRas (mouse)
  • LIN28A (mouse)
  • LIN28B (mouse)
  • LKB1 (human)
  • LKB1 (mouse)
  • mAChR M3 (human)
  • MC4R (human)
  • P2Y6 (human)
  • p53 (human)
  • p70S6K (mouse)
  • PAK4 (mouse)
  • PDK1 (human)
  • PHLPP (human)
  • PIK3CA (mouse)
  • PTEN (human)
  • PTEN (mouse)
  • RAG1 (mouse)
  • Raptor (human)
  • Raptor (mouse)
  • RHEB (human)
  • RICTOR (mouse)
  • S6 (human)
  • syndecan-4 (mouse)
  • TBC1D1 (mouse)
  • TCF7 (human)
  • TDGF1 (mouse)
  • TNFRSF18 (human)
  • TRAF3 (human)
  • TRIP8 (mouse)
  • TSC1 (human)
  • TSC1 (mouse)
  • TSC2 (mouse)
  • UCN2 (human)
  • USP1 (human)
  • Vimentin (human)
  • ZFP91 (human)
Treatment
  • 17-beta-estradiol
  • 4-HT
  • 991
  • A-443654
  • acadesine
  • Akt-I-1
  • Akt_inhibitor_VIII
  • AMDE-1
  • amino_acids
  • antibody
  • antigenic stimulation
  • B7
  • bacterial infection
  • bicuculline
  • BMS-536924
  • BSO
  • butyrate
  • calorie_restriction
  • CB839
  • CGRP
  • CNO
  • colforsin
  • culturing_of_cells
  • dactolisib
  • EGF
  • Epo
  • fasting
  • fedratinib
  • fructose
  • glucose
  • glycine
  • H-89
  • HC-5404
  • high-fat diet
  • IBMX
  • idelalisib
  • IGF-1
  • IL-11
  • IL-12
  • IL-15
  • IL-3
  • IL-33
  • imatinib
  • injury
  • insulin
  • ipatasertib
  • L-glutamine_withdrawal
  • LIF withdrawal
  • linsitinib
  • LPA
  • LPS
  • LTV-1
  • LY294002
  • meal feeding
  • miRNA
  • MK-2206
  • Mn(2+)
  • MPA
  • MRTX1133
  • NAG-thiazoline
  • NBD_peptide
  • Necrostatin-1
  • nitric_oxide
  • norepinephrine
  • NP68
  • NVP-AEW541
  • NVP-BKM120
  • okadaic_acid
  • orexin
  • OSMI-1
  • palbociclib
  • palmitate
  • PD184352
  • PP2
  • Proopiomelanocortin
  • PUGNAc
  • RAD001
  • RAMH
  • rapamycin
  • refeeding
  • S961
  • SEL24-B489
  • serum
  • serum_starvation
  • SF1670
  • siRNA
  • sleep deprivation
  • starvation_medium
  • TEVs
  • TGF-beta
  • TNF
  • Torin1
  • Trametinib
  • tunicamycin
  • U0126
  • wortmannin
  • XL-147
  • Z-VAD-FMK
S6 (human) AKRRRLssLRAstsK S236-p
S6 (mouse) AKRRRLssLRAstsK S236-p
S6 (rat) AKRRRLssLRAstsK S236-p
S6 (fruit fly) AKRRRSASIRESKSS S235
S6 (cow) AKRRRLssLRAsTSK S236-p
S240-p
RLssLRAstsKsEss
Upstream
Downstream
123 912
S6 (human)
S240-p
S6 (mouse)
S240-p
S6 (rat)
S240-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • carcinogenesis, induced
  • carcinogenesis, inhibited
Regulatory protein:
  • Akt1 (mouse)
  • Akt2 (mouse)
  • APP (human)
  • FLT3 (mouse)
  • FOXO1A (mouse)
  • Fyn (mouse)
  • GADD34 (human)
  • leptin (mouse)
  • LKB1 (mouse)
  • Mnk1 (human)
  • Mnk2 (human)
  • mTOR (mouse)
  • PAK4 (human)
  • PDK1 (mouse)
  • PSEN1 (human)
  • Raptor (human)
  • RHEB (mouse)
  • ROCK1 (mouse)
  • SGK1 (human)
  • Sin1 (human)
  • Sin1 (mouse)
  • SynGAP (human)
  • Tau (human)
  • TSC1 (human)
  • TSC1 (mouse)
  • TSC2 (human)
  • TSC2 (mouse)
  • USP1 (human)
Treatment
  • actinomycin_D
  • amino_acid_starvation
  • antibody
  • argimesna
  • AZD8055
  • BI-D1870
  • BX795
  • cannabidiol
  • CL316,243
  • dactolisib
  • dapagliflozin
  • DON
  • eFT508
  • EGF
  • ethanol
  • exercise
  • fasting
  • glutamine
  • H-CHO
  • H2
  • high-fat diet
  • IBMX
  • IGF-1
  • IKK_inhibitor_VII
  • IL-2
  • IL-33
  • injury
  • INK-128
  • insulin
  • leucine
  • lithium
  • low_temperature
  • LPS
  • LY294002
  • meal feeding
  • MK-2206
  • myriocin
  • NKH_477
  • NP68
  • palbociclib
  • palmitate
  • PD184352
  • phorbol_ester
  • PIK90
  • PP2
  • PP242
  • RAD001
  • RAMH
  • rapamycin
  • refeeding
  • retinoic_acid
  • RMC-6272
  • serum
  • streptozotocin
  • Torin1
  • U0126
  • Wnt10b
  • Wnt3a
  • wortmannin
S6 (human) RLssLRAstsKsEss S240-p
S6 (mouse) RLssLRAstsKsEss S240-p
S6 (rat) RLssLRAstsKsESs S240-p
S6 (fruit fly) RSASIRESKSSVSSD S239
S6 (cow) RLssLRAsTSKSESS S240-p
T241-p
LssLRAstsKsEssQ
Upstream
1 286
Regulatory protein:
  • leptin (mouse)
  • TSC1 (human)
Treatment
  • IL-33
S6 (human) LssLRAstsKsEssQ T241-p
S6 (mouse) LssLRAstsKsEssQ T241-p
S6 (rat) LssLRAstsKsESsQ T241-p
S6 (fruit fly) SASIRESKSSVSSDK K240
S6 (cow) LssLRAsTSKSESSQ T241
S242-p
ssLRAstsKsEssQK
Upstream
1 293
Regulatory protein:
  • TSC1 (human)
Treatment
  • rapamycin
S6 (human) ssLRAstsKsEssQK S242-p
S6 (mouse) ssLRAstsKsEssQK S242-p
S6 (rat) ssLRAstsKsESsQK S242-p
S6 (fruit fly) ASIRESKSSVSSDKK S241
S6 (cow) ssLRAsTSKSESSQK S242
S244-p
LRAstsKsEssQK__
Upstream
Downstream
120 595
S6 (human)
S244-p
S6 (mouse)
S244-p
S6 (rat)
S244-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Effects on Biological Processes:
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • neural plasticity
  • transcription, altered
  • transcription, induced
Regulatory protein:
  • Akt1 (mouse)
  • Akt2 (mouse)
  • APP (human)
  • CDC42 (mouse)
  • FOXO1A (mouse)
  • Fyn (mouse)
  • GADD34 (human)
  • LKB1 (mouse)
  • Mnk1 (human)
  • Mnk2 (human)
  • mTOR (mouse)
  • PAK4 (human)
  • PAK4 (mouse)
  • PDK1 (mouse)
  • PSEN1 (human)
  • Raptor (human)
  • RHEB (mouse)
  • ROCK1 (mouse)
  • SGK1 (human)
  • Sin1 (human)
  • Sin1 (mouse)
  • SynGAP (human)
  • Tau (human)
  • TSC1 (human)
  • TSC1 (mouse)
  • TSC2 (human)
  • TSC2 (mouse)
  • USP1 (human)
Treatment
  • 2-APB
  • actinomycin_D
  • amino_acid_starvation
  • antibody
  • argimesna
  • AZD8055
  • BI-D1870
  • BX795
  • cannabidiol
  • CL316,243
  • CNO
  • contextual fear conditioning
  • dactolisib
  • dapagliflozin
  • DON
  • eFT508
  • EGF
  • ethanol
  • exercise
  • fasting
  • glutamine
  • H-CHO
  • H2
  • high-fat diet
  • IBMX
  • IGF-1
  • IKK_inhibitor_VII
  • IL-2
  • injury
  • insulin
  • JMV2959
  • leucine
  • lithium
  • low_temperature
  • LPS
  • LY294002
  • meal feeding
  • myriocin
  • NKH_477
  • NP68
  • palbociclib
  • palmitate
  • PD184352
  • phorbol_ester
  • PIK90
  • PP2
  • PP242
  • RAMH
  • rapamycin
  • refeeding
  • retinoic_acid
  • serum
  • SKF81297
  • sleep deprivation
  • streptozotocin
  • Torin1
  • U0126
  • Wnt10b
  • Wnt3a
  • wortmannin
S6 (human) LRAstsKsEssQK__ S244-p
S6 (mouse) LRAstsKsEssQK__ S244-p
S6 (rat) LRAstsKsESsQK__ S244-p
S6 (fruit fly) IRESKSSVSSDKK__ V243
S6 (cow) LRAsTSKSESSQK__ S244
S246-p
AstsKsEssQK____
Upstream
2 133
Regulatory protein:
  • TSC1 (human)
Treatment
  • INK-128
  • insulin
  • LY294002
  • MK-2206
  • RAD001
  • rapamycin
  • RMC-6272
S6 (human) AstsKsEssQK____ S246-p
S6 (mouse) AstsKsEssQK____ S246-p
S6 (rat) AstsKsESsQK____ S246
S6 (fruit fly) ESKSSVSSDKK____ S245
S6 (cow) AsTSKSESSQK____ S246
S247-p
stsKsEssQK_____
Upstream
Downstream
7 324
Effects on Biological Processes:
  • carcinogenesis, induced
  • transcription, altered
  • transcription, induced
Regulatory protein:
  • KRas (mouse)
  • TSC1 (human)
Treatment
  • CNO
  • contextual fear conditioning
  • insulin
  • MK-2206
  • rapamycin
  • sleep deprivation
S6 (human) stsKsEssQK_____ S247-p
S6 (mouse) stsKsEssQK_____ S247-p
S6 (rat) stsKsESsQK_____ S247-p
S6 (fruit fly) SKSSVSSDKK_____ D246
S6 (cow) sTSKSESSQK_____ S247