Other Species / Isoforms
  separase (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
N3
_____MRNFKGVNFA
0 2
separase (human) _____MRsFKRVNFG S3-p
separase (mouse) _____MRNFKGVNFA N3
separase (rat) _____MRNFKGVKFA N3
K64
CTQQLTAKLDCPGHL
0 2
separase (human) CNQQLTAkLACPRHL K64-ub
separase (mouse) CTQQLTAKLDCPGHL K64
separase (rat) CTQQLTAKLDGPGHL K64
Y140
GEAAPQDYEAVTRGS
0 1
separase (human) REAAPQDyEAVARGS Y140-p
separase (mouse) GEAAPQDYEAVTRGS Y140
separase (rat) REAAPQDYEAVTRGT Y140
K153
GSFSLFWKGAEALLE
0 1
separase (human) GSFSLLWkGAEALLE K153-ub
separase (mouse) GSFSLFWKGAEALLE K153
separase (rat) GTFSLLWKGAEALSE K153
S239-p
LVGEGGSsPGPLSPQ
Upstream
0 1
Regulatory protein:
  • RIPK3 (mouse)
separase (human) LVGERGSSSGLLSPQ S239
separase (mouse) LVGEGGSsPGPLSPQ S239-p
separase (rat) LVGEGGRASGPLSPQ A239
R277
QAARAVERARNHLEK
0 2
separase (human) KAISAVEkAHSYLRN K277-ub
separase (mouse) QAARAVERARNHLEK R277
separase (rat) KATIAVEKTRDHLGN K277
E299
QLCQMGVELLEAVEE
0 1
separase (human) QLCQLGVkLLQVGEE K299-ub
separase (mouse) QLCQMGVELLEAVEE E299
separase (rat) QLCQMGVELLEAVEE E299
Q313
ERPGAVAQLLRKAAA
0 2
separase (human) EGPQAVAkLLIKASA K313-ub
separase (mouse) ERPGAVAQLLRKAAA Q313
separase (rat) ERPGAVAQLLMKAAA Q313
N324
KAAAVLINSIEAPSP
0 1
separase (human) KASAVLSkSMEAPSP K324-ub
separase (mouse) KAAAVLINSIEAPSP N324
separase (rat) KAAAILNSSMDGPSP S324
T486
CQHLGSATSGACPEV
0 1
separase (human) CQHLGLVkPGTYPEV K491-ub
separase (mouse) CQHLGSATSGACPEV T486
separase (rat) CQHLGLAKSGACPEV K486
K557
DASRAGDKELQLQTL
0 1
separase (human) DAARAGDkELQLkTL K562-ac
separase (mouse) DASRAGDKELQLQTL K557
separase (rat) DAAKAGDKELQLQTL K557
K557
DASRAGDKELQLQTL
0 2
separase (human) DAARAGDkELQLkTL K562-ub
separase (mouse) DASRAGDKELQLQTL K557
separase (rat) DAAKAGDKELQLQTL K557
Q562
GDKELQLQTLRDSLS
0 2
separase (human) GDkELQLkTLRDSLS K567-ub
separase (mouse) GDKELQLQTLRDSLS Q562
separase (rat) GDKELQLQTLRDSLS Q562
K588
REELRAYKSVRADTG
0 2
separase (human) REELQAYkAVRADTG K593-ub
separase (mouse) REELRAYKSVRADTG K588
separase (rat) REELQAYKAVRADTG K588
Y714
FEVNDLNYEDKLQED
0 1
separase (human) FEVNDLNyEDkLQED Y719-p
separase (mouse) FEVNDLNYEDKLQED Y714
separase (rat) FEVNDLNYEDKLQED Y714
K717
NDLNYEDKLQEDRFL
0 2
separase (human) NDLNyEDkLQEDRFL K722-ub
separase (mouse) NDLNYEDKLQEDRFL K717
separase (rat) NDLNYEDKLQEDRFL K717
K750
DQALTLWKEVLTKGR
0 1
separase (human) DQALALWkELLTkGQ K755-ub
separase (mouse) DQALTLWKEVLTKGR K750
separase (rat) DQALTLWKEVLTKEP K750
K755
LWKEVLTKGRAPAVR
0 2
separase (human) LWkELLTkGQAPAVR K760-ub
separase (mouse) LWKEVLTKGRAPAVR K755
separase (rat) LWKEVLTKEPAPAVR K755
A805
SKRLQDHAKAASSSC
0 1
separase (human) SERLKDHsKAAGSSC S810-p
separase (mouse) SKRLQDHAKAASSSC A805
separase (rat) SKRLQDHAKAVSSSC A805
Y968
TESPFLDYGENLVQK
0 1
separase (human) VETSFLDyGENLVQK Y973-p
separase (mouse) TESPFLDYGENLVQK Y968
separase (rat) VESPFLDYGENLVQK Y968
K1003
LGNVSEAKAFCLEAL
0 3
separase (human) LGSVSEAkAFCLEAL K1008-ub
separase (mouse) LGNVSEAKAFCLEAL K1003
separase (rat) LGNVSEAKAFCLEAL K1003
K1011
AFCLEALKLTTKLQI
0 2
separase (human) AFCLEALkLTTkLQI K1016-ub
separase (mouse) AFCLEALKLTTKLQI K1011
separase (rat) AFCLEALKLTTKLQI K1011
K1015
EALKLTTKLQIPRQC
0 1
separase (human) EALkLTTkLQIPRQC K1020-ub
separase (mouse) EALKLTTKLQIPRQC K1015
separase (rat) EALKLTTKLQIPRQC K1015
S1068
VVTQHPDSVKKVHTQ
1 1
separase (human) GVTQHLDsVKKVHLQ S1073-p
separase (mouse) VVTQHPDSVKKVHTQ S1068
separase (rat) VVTQHPDSVKRVHTQ S1068
K1078
KVHTQKGKHKAQGPC
0 1
separase (human) KVHLQKGkQQAQVPC K1083-ub
separase (mouse) KVHTQKGKHKAQGPC K1078
separase (rat) RVHTQKGTHKAQVPC T1078
T1106
PALELVDTVLNEPGP
0 1
separase (human) PALELVAtVAKEPGP T1111-p
separase (mouse) PALELVDTVLNEPGP T1106
separase (rat) PALELVATVLKEPGP T1106
V1118
PGPIQSSVNssPVLK
0 1
separase (human) PGPIAPStNSsPVLK T1123-p
separase (mouse) PGPIQSSVNssPVLK V1118
separase (rat) PGPIQPSGNSSPVLK G1118
S1120-p
PIQSSVNssPVLKTK
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
separase (human) PIAPStNSsPVLKTK S1125
separase (mouse) PIQSSVNssPVLKTK S1120-p
separase (rat) PIQPSGNSSPVLKTK S1120
S1121-p
IQSSVNssPVLKTKP
Downstream
11 9
Effects on Modified Protein
  • activity, inhibited
  • enzymatic activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
  • cell growth, altered
  • cell growth, induced
  • cell growth, inhibited
  • chromatin organization, altered
separase (human) IAPStNSsPVLKTKP S1126-p
separase (mouse) IQSSVNssPVLKTKP S1121-p
separase (rat) IQPSGNSSPVLKTKA S1121
S1148
CDCLLCASPALSAVC
1 0
separase (human) CDCSLCAsPVLTAVC S1153-p
separase (mouse) CDCLLCASPALSAVC S1148
separase (rat) CDCLLCASPALSTVC S1148
T1184
DLLQAVLTRCPAATK
0 1
separase (human) DLLQVVLkGCPEAAE K1189-ub
separase (mouse) DLLQAVLTRCPAATK T1184
separase (rat) DLLQAVLKGCPAATK K1184
T1205
QASLNHRTTPSCVPS
0 1
separase (human) QASLNHKtPPSLVPS T1210-p
separase (mouse) QASLNHRTTPSCVPS T1205
separase (rat) QTSLNHKAPPSCVPS A1205
K1247
KVLASGLKFVATRIQ
0 1
separase (human) KVLQSGLkFVAARIP K1252-ub
separase (mouse) KVLASGLKFVATRIQ K1247
separase (rat) KVLASGLKFVATRIQ K1247
L1300
LVKSLPVLEPAKIRR
1 1
separase (human) LIKSVPGsEPSkTQG S1305-p
separase (mouse) LVKSLPVLEPAKIRR L1300
separase (rat) LVKIPPVLEPSKIRR L1300
K1304
LPVLEPAKIRRQKCS
0 1
separase (human) VPGsEPSkTQGQKRs K1309-ub
separase (mouse) LPVLEPAKIRRQKCS K1304
separase (rat) PPVLEPSKIRRQKCS K1304
S1311
KIRRQKCSGRGRRRI
0 1
separase (human) kTQGQKRsGRGRQkL S1316-p
separase (mouse) KIRRQKCSGRGRRRI S1311
separase (rat) KIRRQKCSGQGRQRV S1311
R1317
CSGRGRRRIAsVPPP
0 2
separase (human) RsGRGRQkLAsAPLR K1322-ub
separase (mouse) CSGRGRRRIAsVPPP R1317
separase (rat) CSGQGRQRVASAPSP R1317
S1320-p
RGRRRIAsVPPPLHN
Upstream
0 2
Treatment
  • IL-33
separase (human) RGRQkLAsAPLRLNN S1325-p
separase (mouse) RGRRRIAsVPPPLHN S1320-p
separase (rat) QGRQRVASAPSPLHS S1320
K1331
PLHNSSQKGLEEEGP
0 1
separase (human) RLNNTSQkGLEGrGL K1336-ub
separase (mouse) PLHNSSQKGLEEEGP K1331
separase (rat) PLHSSSQEGLEEGPP E1331
E1336
SQKGLEEEGPPCtPK
0 1
separase (human) SQkGLEGrGLPCtPK R1341-m1
separase (mouse) SQKGLEEEGPPCtPK E1336
separase (rat) SSQEGLEEGPPCTPK E1335
T1341-p
EEEGPPCtPKPPGRA
Downstream
3 3
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
separase (human) EGrGLPCtPKPPDRI T1346-p
separase (mouse) EEEGPPCtPKPPGRA T1341-p
separase (rat) LEEGPPCTPKPPGRA T1340
T1358
AGPRVPFTIFEEVHP
1 1
separase (human) AGPHVPFtVFEEVCP T1363-p
separase (mouse) AGPRVPFTIFEEVHP T1358
separase (rat) AGPRVPFTIFEDIHP T1357
S1391-p
TRLKVIFsDDsDLED
0 11
separase (human) TRLKVNFsDDsDLED S1396-p
separase (mouse) TRLKVIFsDDsDLED S1391-p
separase (rat) TRLKVNFsDDsDLED S1390-p
S1394-p
KVIFsDDsDLEDLVS
1 12
separase (human) KVNFsDDsDLEDPVS S1399-p
separase (mouse) KVIFsDDsDLEDLVS S1394-p
separase (rat) KVNFsDDsDLEDLVS S1393-p
S1428-p
GQTRKGRsLKTDAVV
0 1
separase (human) GRARKGLSLKTDAVV S1433
separase (mouse) GQTRKGRsLKTDAVV S1428-p
separase (rat) GQSRKGPSLKTDAAV S1427
S1439
DAVVAIESTPGHssV
0 1
separase (human) DAVVAPGsAPGNPGL S1444-p
separase (mouse) DAVVAIESTPGHssV S1439
separase (rat) DAAVAVGSTPGHPSL S1438
S1444-p
IESTPGHssVsGRTR
0 1
separase (human) PGsAPGNPGLNGRsR P1449
separase (mouse) IESTPGHssVsGRTR S1444-p
separase (rat) VGSTPGHPSLSGRTR P1443
S1445-p
ESTPGHssVsGRTRR
0 1
separase (human) GsAPGNPGLNGRsRR G1450
separase (mouse) ESTPGHssVsGRTRR S1445-p
separase (rat) GSTPGHPSLSGRTRR S1444
S1447-p
TPGHssVsGRTRRAR
0 1
separase (human) APGNPGLNGRsRRAK N1452
separase (mouse) TPGHssVsGRTRRAR S1447-p
separase (rat) TPGHPSLSGRTRRAR S1446
T1450
HssVsGRTRRARKVA
0 1
separase (human) NPGLNGRsRRAKKVA S1455-p
separase (mouse) HssVsGRTRRARKVA T1450
separase (rat) HPSLSGRTRRARKVA T1449
C1471
ESPKAPLCVWASQGP
0 1
separase (human) ERRPQRAsDQARPGP S1475-p
separase (mouse) ESPKAPLCVWASQGP C1471
separase (rat) VASRHCEGVGASLGP G1462
S1497-p
VDNHLEKsFEILRGs
Upstream
2 12
Regulatory protein:
  • FLT3 (mouse)
separase (human) TDNWRKMsFEILRGs S1501-p
separase (mouse) VDNHLEKsFEILRGs S1497-p
separase (rat) MDSQLEKSFEILRAs S1488
S1504-p
sFEILRGsDGEDsAs
Upstream
1 25
Regulatory protein:
  • FLT3 (mouse)
  • RICTOR (mouse)
separase (human) sFEILRGsDGEDsAS S1508-p
separase (mouse) sFEILRGsDGEDsAs S1504-p
separase (rat) SFEILRAsDGEDsAS S1495-p
S1509-p
RGsDGEDsAsGEKAA
Upstream
0 6
Regulatory protein:
  • FLT3 (mouse)
  • RICTOR (mouse)
separase (human) RGsDGEDsASGGkTP S1513-p
separase (mouse) RGsDGEDsAsGEKAA S1509-p
separase (rat) RAsDGEDsASGEKAA S1500-p
S1511-p
sDGEDsAsGEKAAAA
Upstream
0 1
Regulatory protein:
  • FLT3 (mouse)
separase (human) sDGEDsASGGkTPAP S1515
separase (mouse) sDGEDsAsGEKAAAA S1511-p
separase (rat) sDGEDsASGEKAAAA S1502
K1514
EDsAsGEKAAAADTG
0 1
separase (human) EDsASGGkTPAPGPE K1518-ub
separase (mouse) EDsAsGEKAAAADTG K1514
separase (rat) EDsASGEKAAAAEPG K1505
V1524
AADTGLPVGECEVLR
0 2
separase (human) APGPEAAsGEWELLR S1528-p
separase (mouse) AADTGLPVGECEVLR V1524
separase (rat) AAEPGLPIGEREVLR I1515
S1534
CEVLRRDSSKAERPV
0 5
separase (human) WELLRLDssKKKLPs S1538-p
separase (mouse) CEVLRRDSSKAERPV S1534
separase (rat) REVLRRDSSKAERPV S1525
S1535
EVLRRDSSKAERPVL
0 1
separase (human) ELLRLDssKKKLPsP S1539-p
separase (mouse) EVLRRDSSKAERPVL S1535
separase (rat) EVLRRDSSKAERPVL S1526
V1541
SSKAERPVLYSDTEA
1 2
separase (human) ssKKKLPsPCPDKEs S1545-p
separase (mouse) SSKAERPVLYSDTEA V1541
separase (rat) SSKAERPVLYPDTEA V1532
A1548
VLYSDTEANSDPSPW
1 1
separase (human) sPCPDKEsDKDLGPR S1552-p
separase (mouse) VLYSDTEANSDPSPW A1548
separase (rat) VLYPDTEADSDLSPW A1539
Y1610
CLGHRDPYATAFLVA
0 1
separase (human) CLGHRDPyATAFLVT Y1614-p
separase (mouse) CLGHRDPYATAFLVA Y1610
separase (rat) CLGHRDPYATAFLVA Y1601
S1645
KAQKQQESPELAEHL
0 3
separase (human) KAQKHRGsLEIADQL S1649-p
separase (mouse) KAQKQQESPELAEHL S1645
separase (rat) KAQKQQGSPELAEHL S1636
D1656
AEHLQRLDLKERPGG
1 0
separase (human) ADQLQGLsLQEMPGD S1660-p
separase (mouse) AEHLQRLDLKERPGG D1656
separase (rat) AEHLQRLDLKERPGG D1647
K1688
GCFPQAEKESFQERL
0 2
separase (human) GHFPQPEkESFQERL K1692-ub
separase (mouse) GCFPQAEKESFQERL K1688
separase (rat) GCFPQAEKDSFQKRL K1679
K1728
LLLTRLEKDNPPITV
0 2
separase (human) LLLTRLEkDSPPVSV K1732-ub
separase (mouse) LLLTRLEKDNPPITV K1728
separase (rat) LLLTRLEKDNPPITV K1719
K1743
KIPTAQNKLPLSAVL
0 1
separase (human) QIPTGQNkLHLRsVL K1747-ub
separase (mouse) KIPTAQNKLPLSAVL K1743
separase (rat) KIPTAQSKFPLSAVL K1734
A1748
QNKLPLSAVLKEFDA
0 1
separase (human) QNkLHLRsVLNEFDA S1752-p
separase (mouse) QNKLPLSAVLKEFDA A1748
separase (rat) QSKFPLSAVLKEFDA A1739
K1758
KEFDAIQKDQKENSS
0 1
separase (human) NEFDAIQkAQKENss K1762-ub
separase (mouse) KEFDAIQKDQKENSS K1758
separase (rat) KEFDAIQKDQKENSG K1749
S1764
QKDQKENSSCTEKRV
0 1
separase (human) QkAQKENssCtDKRE S1768-p
separase (mouse) QKDQKENSSCTEKRV S1764
separase (rat) QKDQKENSGCTEKRA S1755
S1765
KDQKENSSCTEKRVW
0 1
separase (human) kAQKENssCtDKREW S1769-p
separase (mouse) KDQKENSSCTEKRVW S1765
separase (rat) KDQKENSGCTEKRAW G1756
T1767
QKENSSCTEKRVWWT
0 1
separase (human) QKENssCtDKREWWT T1771-p
separase (mouse) QKENSSCTEKRVWWT T1767
separase (rat) QKENSGCTEKRAWWT T1758
E1792
ALITALEEQVLGCWR
0 1
separase (human) VLIASLEkSVLGCWk K1796-ub
separase (mouse) ALITALEEQVLGCWR E1792
separase (rat) ELITSLEEHVLGCWR E1783
R1799
EQVLGCWRGLLLPCS
0 3
separase (human) kSVLGCWkGLLLPSS K1803-ub
separase (mouse) EQVLGCWRGLLLPCS R1799
separase (rat) EHVLGCWRGLLLPCS R1790
S1816
PSLAQEASKLQELLR
0 1
separase (human) PGPAQEAsRLQELLQ S1820-p
separase (mouse) PSLAQEASKLQELLR S1816
separase (rat) PGLSQEASQLQELLH S1807
E1828
LLRECGWEYPDSTLL
0 4
separase (human) LLQDCGWkYPDRTLL K1832-ub
separase (mouse) LLRECGWEYPDSTLL E1828
separase (rat) LLHECGWEYPDYTLL E1819
E1880
VGQVQSQEAPRSQHL
0 1
separase (human) VGRLQGLtVPsNsHL T1884-p
separase (mouse) VGQVQSQEAPRSQHL E1880
separase (rat) VGRVQSQAAPPSQHL A1871
R1883
VQSQEAPRSQHLVLV
0 1
separase (human) LQGLtVPsNsHLVLV S1887-p
separase (mouse) VQSQEAPRSQHLVLV R1883
separase (rat) VQSQAAPPSQHLVLV P1874
Q1885
SQEAPRSQHLVLVLD
0 1
separase (human) GLtVPsNsHLVLVLD S1889-p
separase (mouse) SQEAPRSQHLVLVLD Q1885
separase (rat) SQAAPPSQHLVLVLD Q1876
K1897
VLDKDLQKLPWESTP
0 1
separase (human) VLDKDLQkLPWESMP K1901-ub
separase (mouse) VLDKDLQKLPWESTP K1897
separase (rat) VLDKDLQKLPWESMP K1888
E1990
QVQAALTERDLYIYA
0 2
separase (human) QVQEALTkHDLYIYA K1994-ub
separase (mouse) QVQAALTERDLYIYA E1990
separase (rat) QVQAALTEHDLYIYA E1981
K2099
ARQAPRLKYLIGAAP
0 1
separase (human) ARQAPRLkyLIGAAP K2103-ub
separase (mouse) ARQAPRLKYLIGAAP K2099
separase (rat) ARQAPRLKYLIGAAP K2090
Y2100
RQAPRLKYLIGAAPV
0 1
separase (human) RQAPRLkyLIGAAPI Y2104-p
separase (mouse) RQAPRLKYLIGAAPV Y2100
separase (rat) RQAPRLKYLIGAAPV Y2091
S2114
VAYGLPISLQTP___
0 1
separase (human) IAYGLPVsLR_____ S2118-p
separase (mouse) VAYGLPISLQTP___ S2114
separase (rat) VAYGLPVSLQTS___ S2105