Other Species / Isoforms
  eIF2B-epsilon (rat)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T4
____MAATAAVPSAV
0 1
eIF2B-epsilon (human) ___MAAPVVAPPGVV V5
eIF2B-epsilon (mouse) ____MAAtAAVPGAA T4-p
eIF2B-epsilon (rat) ____MAATAAVPSAV T4
eIF2B-epsilon (rabbit) ___MATTVVAPPGAV V5
N16
SAVGGRANKRGGGsG
0 3
eIF2B-epsilon (human) GVVVSRANKRsGAGP N17
eIF2B-epsilon (mouse) GAAAGRAsKrGGGGS S16-p
eIF2B-epsilon (rat) SAVGGRANKRGGGsG N16
eIF2B-epsilon (rabbit) GAVSDRANKRGGGPG N17
R18
VGGRANKRGGGsGGG
0 13
eIF2B-epsilon (human) VVSRANKRsGAGPGG R19
eIF2B-epsilon (mouse) AAGRAsKrGGGGSGG R18-m1
eIF2B-epsilon (rat) VGGRANKRGGGsGGG R18
eIF2B-epsilon (rabbit) VSDRANKRGGGPGGG R19
G19
GGRANKRGGGsGGGG
0 1
eIF2B-epsilon (human) VSRANKRsGAGPGGs S20-p
eIF2B-epsilon (mouse) AGRAsKrGGGGSGGG G19
eIF2B-epsilon (rat) GGRANKRGGGsGGGG G19
eIF2B-epsilon (rabbit) SDRANKRGGGPGGGG G20
S22-p
ANKRGGGsGGGGTQG
1 2
eIF2B-epsilon (human) sGAGPGGsGGGGARG S27-p
eIF2B-epsilon (mouse) sKrGGGGSGGGGTQG S23
eIF2B-epsilon (rat) ANKRGGGsGGGGTQG S22-p
eIF2B-epsilon (rabbit) GGGPGGGGGGGGARG G27
K56-ub
RRFFPISkDQPRVLL
1 2
eIF2B-epsilon (human) RRFFPISkDQPRVLL K61-ub
eIF2B-epsilon (mouse) RRFFPISKDQPRVLL K57
eIF2B-epsilon (rat) RRFFPISkDQPRVLL K56-ub
eIF2B-epsilon (rabbit) RRFFPISKDQPRVLL K61
K98-ub
CWKAAQIkEHLQKSK
1 3
eIF2B-epsilon (human) CWKAAQIkEHLLkSK K103-ub
eIF2B-epsilon (mouse) CWKAAQIKEHLQKSK K99
eIF2B-epsilon (rat) CWKAAQIkEHLQKSK K98-ub
eIF2B-epsilon (rabbit) CWKAAQIKEHLQKSK K103
K103
QIkEHLQKSKWCHPT
0 1
eIF2B-epsilon (human) QIkEHLLkSKWCRPT K108-ub
eIF2B-epsilon (mouse) QIKEHLQKSKWCHPT K104
eIF2B-epsilon (rat) QIkEHLQKSKWCHPT K103
eIF2B-epsilon (rabbit) QIKEHLQKSKWCRPT K108
S125-p
ITSDLYRsLGDVLRD
1 1
eIF2B-epsilon (human) ITSELYRSLGDVLRD S130
eIF2B-epsilon (mouse) ITSELYRSLGDVLRD S126
eIF2B-epsilon (rat) ITSDLYRsLGDVLRD S125-p
eIF2B-epsilon (rabbit) ITSELYRSLGDVLRD S130
K136-ub
VLRDVDAkALVRSDF
1 4
eIF2B-epsilon (human) VLRDVDAkALVRSDF K141-ub
eIF2B-epsilon (mouse) VLRDVDAKALVRSDF K137
eIF2B-epsilon (rat) VLRDVDAkALVRSDF K136-ub
eIF2B-epsilon (rabbit) VLRDVDAKALVRSDF K141
T177
EKNVSVMTMVFKESS
0 1
eIF2B-epsilon (human) EKNVSVMtMIFkESS T182-p
eIF2B-epsilon (mouse) EKNVSVMTMVFKESS T178
eIF2B-epsilon (rat) EKNVSVMTMVFKESS T177
eIF2B-epsilon (rabbit) EKNVSVMTMIFKESS T182
K181
SVMTMVFKESSPSHP
0 1
eIF2B-epsilon (human) SVMtMIFkESSPSHP K186-ub
eIF2B-epsilon (mouse) SVMTMVFKESSPSHP K182
eIF2B-epsilon (rat) SVMTMVFKESSPSHP K181
eIF2B-epsilon (rabbit) SVMTMIFKESSPSHP K186
K212-ub
NRILHFQkTQGLRHF
1 2
eIF2B-epsilon (human) NRVLHFQkTQGLRRF K217-ub
eIF2B-epsilon (mouse) NRVLHFQKTQGLRRF K213
eIF2B-epsilon (rat) NRILHFQkTQGLRHF K212-ub
eIF2B-epsilon (rabbit) NRILHFQKTQGLRRF K217
G224
RHFSFPLGLFQGSLD
0 1
eIF2B-epsilon (human) RRFAFPLSLFQGSSD S229
eIF2B-epsilon (mouse) RRFSFPLsLFQGSGD S225-p
eIF2B-epsilon (rat) RHFSFPLGLFQGSLD G224
eIF2B-epsilon (rabbit) RRFSFPLSLFQGSGA S229
Y314
DVIRRWVYPLtPEVN
0 3
eIF2B-epsilon (human) DVIRRWVyPLTPEAN Y319-p
eIF2B-epsilon (mouse) DVIRRWVYPLTPEVN Y315
eIF2B-epsilon (rat) DVIRRWVYPLtPEVN Y314
eIF2B-epsilon (rabbit) DVIRRWVYPLTPEAN Y319
T317-p
RRWVYPLtPEVNFTD
1 1
eIF2B-epsilon (human) RRWVyPLTPEANFTD T322
eIF2B-epsilon (mouse) RRWVYPLTPEVNFTD T318
eIF2B-epsilon (rat) RRWVYPLtPEVNFTD T317-p
eIF2B-epsilon (rabbit) RRWVYPLTPEANFTD T322
K415
LCDRAEVKERVILKP
0 1
eIF2B-epsilon (human) LCDNAEVkERVTLKP K420-ub
eIF2B-epsilon (mouse) LCDRAEVKERVKLKP K416
eIF2B-epsilon (rat) LCDRAEVKERVILKP K415
eIF2B-epsilon (rabbit) LCDHAEVKEQVTLKP K420
S442
DIILPEGSVISLHPP
0 1
eIF2B-epsilon (human) NITLPEGsVIsLHPP S447-p
eIF2B-epsilon (mouse) DITLPEGSVISLHPP S443
eIF2B-epsilon (rat) DIILPEGSVISLHPP S442
eIF2B-epsilon (rabbit) NITLPEGSVISLHPP S447
S445
LPEGSVISLHPPDAE
0 1
eIF2B-epsilon (human) LPEGsVIsLHPPDAE S450-p
eIF2B-epsilon (mouse) LPEGSVISLHPPDAE S446
eIF2B-epsilon (rat) LPEGSVISLHPPDAE S445
eIF2B-epsilon (rabbit) LPEGSVISLHPPDAE S450
S461-p
DEDDGQFsDDsGADQ
3 3
eIF2B-epsilon (human) DEDDGEFsDDsGADQ S466-p
eIF2B-epsilon (mouse) DEDDGQFsDDsGADQ S462-p
eIF2B-epsilon (rat) DEDDGQFsDDsGADQ S461-p
eIF2B-epsilon (rabbit) DEDDGQFSDDSGVNQ S466
S464-p
DGQFsDDsGADQEKE
Upstream
2 3
Kinase, in vitro:
  • CK1A (human)
eIF2B-epsilon (human) DGEFsDDsGADQEKD S469-p
eIF2B-epsilon (mouse) DGQFsDDsGADQEKE S465-p
eIF2B-epsilon (rat) DGQFsDDsGADQEKE S464-p
eIF2B-epsilon (rabbit) DGQFSDDSGVNQAKE S469
K476
EKEKVKLKGYNPAEV
0 3
eIF2B-epsilon (human) EKDKVKMkGyNPAEV K481-ub
eIF2B-epsilon (mouse) EKEKVKLkGYNPAEV K477-ub
eIF2B-epsilon (rat) EKEKVKLKGYNPAEV K476
eIF2B-epsilon (rabbit) AKEKAKLKGYNPAEV K481
Y478
EKVKLKGYNPAEVGP
0 1
eIF2B-epsilon (human) DKVKMkGyNPAEVGA Y483-p
eIF2B-epsilon (mouse) EKVKLkGYNPAEVGL Y479
eIF2B-epsilon (rat) EKVKLKGYNPAEVGP Y478
eIF2B-epsilon (rabbit) EKAKLKGYNPAEVGV Y483
Q488
AEVGPEGQGYLWKAE
0 3
eIF2B-epsilon (human) AEVGAAGkGYLWKAA K493-ub
eIF2B-epsilon (mouse) AEVGLEGQGYLWKAE Q489
eIF2B-epsilon (rat) AEVGPEGQGYLWKAE Q488
eIF2B-epsilon (rabbit) AEVGVAGKGYLWKAA K493
K500-ub
KAEDVDEkEDEELRQ
1 1
eIF2B-epsilon (human) KAAGMNMEEEEELQQ E505
eIF2B-epsilon (mouse) KAEGVNSKEDEELRQ K501
eIF2B-epsilon (rat) KAEDVDEkEDEELRQ K500-ub
eIF2B-epsilon (rabbit) KAADMNTEKEEELRQ E505
S520
MINMEEESETESERs
1 1
eIF2B-epsilon (human) KINMEEEsEsEsEQs S525-p
eIF2B-epsilon (mouse) MIKTEEESETESEGS S521
eIF2B-epsilon (rat) MINMEEESETESERs S520
eIF2B-epsilon (rabbit) TINEEEESETESERS S525
T522
NMEEESETESERsVD
0 1
eIF2B-epsilon (human) NMEEEsEsEsEQsMD S527-p
eIF2B-epsilon (mouse) KTEEESETESEGSVD T523
eIF2B-epsilon (rat) NMEEESETESERsVD T522
eIF2B-epsilon (rabbit) NEEEESETESERSMD T527
S524
EEESETESERsVDPE
0 1
eIF2B-epsilon (human) EEEsEsEsEQsMDsE S529-p
eIF2B-epsilon (mouse) EEESETESEGSVDPE S525
eIF2B-epsilon (rat) EEESETESERsVDPE S524
eIF2B-epsilon (rabbit) EEESETESERSMDSE S529
S527-p
SETESERsVDPEELD
0 2
eIF2B-epsilon (human) sEsEsEQsMDsEEPD S532-p
eIF2B-epsilon (mouse) SETESEGSVDPEELD S528
eIF2B-epsilon (rat) SETESERsVDPEELD S527-p
eIF2B-epsilon (rabbit) SETESERSMDSEELD S532
P530
ESERsVDPEELDsRA
0 1
eIF2B-epsilon (human) EsEQsMDsEEPDsRG S535-p
eIF2B-epsilon (mouse) ESEGSVDPEELDsRA P531
eIF2B-epsilon (rat) ESERsVDPEELDsRA P530
eIF2B-epsilon (rabbit) ESERSMDSEELDSRA S535
S535-p
VDPEELDsRAGsPQL
Upstream
Downstream
10 3
Effects on Biological Processes:
  • cell growth, altered
  • cytoskeletal reorganization
  • signaling pathway regulation
  • translation, altered
  • translation, inhibited
Kinase, in vitro:
  • GSK3A (rat)
  • GSK3B (human)
  • GSK3B (rat)
Putative in vivo kinases:
  • GSK3B (rat)
Regulatory protein:
  • TICAM1 (human)
Treatment
  • antibody
  • endothelin
  • exercise
  • insulin
  • isoproterenol
  • lithium
  • LPS
  • LY294002
  • phorbol_ester
  • prazosin
  • propranolol
  • rapamycin
  • SB216763
  • SB415286
  • sepsis
  • serum
  • tunicamycin
eIF2B-epsilon (human) MDsEEPDsRGGsPQM S540-p
eIF2B-epsilon (mouse) VDPEELDsRAGsPQL S536-p
eIF2B-epsilon (rat) VDPEELDsRAGsPQL S535-p
eIF2B-epsilon (rabbit) MDSEELDSRAGSPQL S540
S539-p
ELDsRAGsPQLDDIR
Upstream
5 85
Kinase, in vitro:
  • DYRK1A (human)
  • DYRK2 (human)
  • ERK2 (human)
Treatment
  • PDGF
  • serum
eIF2B-epsilon (human) EPDsRGGsPQMDDIK S544-p
eIF2B-epsilon (mouse) ELDsRAGsPQLDDIR S540-p
eIF2B-epsilon (rat) ELDsRAGsPQLDDIR S539-p
eIF2B-epsilon (rabbit) ELDSRAGSPQLDDIK S544
R560
LGTLQRGREENISCD
0 1
eIF2B-epsilon (human) LGTLQRGkEENISCD K565-ub
eIF2B-epsilon (mouse) LGTLQRGREENISCE R561
eIF2B-epsilon (rat) LGTLQRGREENISCD R560
eIF2B-epsilon (rabbit) LGTLQRGKEESISCD K565
Y578
LEINSLKYAYNISLK
0 1
eIF2B-epsilon (human) LEINSLKyAYNISLK Y583-p
eIF2B-epsilon (mouse) LEINSLKHAYNISLK H579
eIF2B-epsilon (rat) LEINSLKYAYNISLK Y578
eIF2B-epsilon (rabbit) LEINSLKYAYNISLK Y583
G605
FPLQQVDGVLDPNRY
0 3
eIF2B-epsilon (human) FPLQQMDsPLDSSRY S610-p
eIF2B-epsilon (mouse) FPLQQVDGLLDPNRY G606
eIF2B-epsilon (rat) FPLQQVDGVLDPNRY G605
eIF2B-epsilon (rabbit) FPLQQMDSPLEANRY S610
K621
ALLLPLLKAWSPVFR
0 1
eIF2B-epsilon (human) ALLLPLLKAWSPVFR K626
eIF2B-epsilon (mouse) ALLLPLLkAWSPVLR K622-ub
eIF2B-epsilon (rat) ALLLPLLKAWSPVFR K621
eIF2B-epsilon (rabbit) ALLLPLLKAWSPVFR K626
K688
SQRDITDKGQQLRKN
0 1
eIF2B-epsilon (human) SQRDTTDkGQQLRKN K693-ub
eIF2B-epsilon (mouse) SQRDTTDEGQQLRKN E689
eIF2B-epsilon (rat) SQRDITDKGQQLRKN K688
eIF2B-epsilon (rabbit) GQRDVTDKGRQLRKN K693
S712-p
LREAEEEssDDD___
Upstream
Downstream
3 12
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CK2A1 (rat)
eIF2B-epsilon (human) LKEAEEEssEDD___ S717-p
eIF2B-epsilon (mouse) LREAEEEssEDD___ S713-p
eIF2B-epsilon (rat) LREAEEEssDDD___ S712-p
eIF2B-epsilon (rabbit) LKEAEEEssEDD___ S717-p
S713-p
REAEEEssDDD____
Upstream
Downstream
3 11
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CK2A1 (rat)
eIF2B-epsilon (human) KEAEEEssEDD____ S718-p
eIF2B-epsilon (mouse) REAEEEssEDD____ S714-p
eIF2B-epsilon (rat) REAEEEssDDD____ S713-p
eIF2B-epsilon (rabbit) KEAEEEssEDD____ S718-p