Other Species / Isoforms
  SMAD3 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T8-p
MSSILPFtPPIVKRL
5 13
SMAD3 (human) MSSILPFtPPIVkRL T8-p
SMAD3 (mouse) MSSILPFtPPIVKRL T8-p
SMAD3 (rat) MSSILPFtPPIVKRL T8-p
K13
PFtPPIVKRLLGWKK
0 4
SMAD3 (human) PFtPPIVkRLLGWkK K13-ub
SMAD3 (mouse) PFtPPIVKRLLGWKK K13
SMAD3 (rat) PFtPPIVKRLLGWKK K13
K19
VKRLLGWKKGEQNGQ
0 5
SMAD3 (human) VkRLLGWkKGEQNGQ K19-ac
SMAD3 (mouse) VKRLLGWKKGEQNGQ K19
SMAD3 (rat) VKRLLGWKKGEQNGQ K19
K29
EQNGQEEKWCEKAVK
0 1
SMAD3 (human) EQNGQEEkWCEKAVK K29-ac
SMAD3 (mouse) EQNGQEEKWCEKAVK K29
SMAD3 (rat) EQNGQEEKWCEKAVK K29
K63
TTQNVNTKCITIPRS
0 1
SMAD3 (human) TTQNVNTkCITIPRS K63-ub
SMAD3 (mouse) TTQNVNTKCITIPRS K63
SMAD3 (rat) TTQNVNTKCITIPRS K63
T132-p
YHYQRVEtPVLPPVL
0 8
SMAD3 (human) YHYQRVEtPVLPPVL T132-p
SMAD3 (mouse) YHYQRVEtPVLPPVL T132-p
SMAD3 (rat) YHYQRVETPVLPPVL T132
T179
PQSNIPETPPPGYLS
13 0
SMAD3 (human) PQSNIPEtPPPGYLS T179-p
SMAD3 (mouse) PQSNIPETPPPGYLS T179
SMAD3 (rat) PQSNIPETPPPGYLS T179
S204-p
NHSMDAGsPNLSPNP
Downstream
14 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, induced
  • signaling pathway regulation
  • transcription, induced
SMAD3 (human) NHSMDAGsPNLsPNP S204-p
SMAD3 (mouse) NHSMDAGsPNLSPNP S204-p
SMAD3 (rat) NHSMDAGSPNLSPNP S204
S208
DAGsPNLSPNPMSPA
14 0
SMAD3 (human) DAGsPNLsPNPMsPA S208-p
SMAD3 (mouse) DAGsPNLSPNPMSPA S208
SMAD3 (rat) DAGSPNLSPNPMSPA S208
S213
NLSPNPMSPAHNNLD
10 0
SMAD3 (human) NLsPNPMsPAHNNLD S213-p
SMAD3 (mouse) NLSPNPMSPAHNNLD S213
SMAD3 (rat) NLSPNPMSPAHNNLD S213
S264
VDGFTDPSNSERFCL
1 0
SMAD3 (human) VDGFTDPsNSERFCL S264-p
SMAD3 (mouse) VDGFTDPSNSERFCL S264
SMAD3 (rat) VDGFTDPSNSERFCL S264
S309-p
EVFAECLsDSAIFVQ
Upstream
Downstream
2 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Putative in vivo kinases:
  • PKG1 (mouse)
Treatment
  • KT5823
  • TGF-beta
SMAD3 (human) EVFAECLsDSAIFVQ S309-p
SMAD3 (mouse) EVFAECLsDSAIFVQ S309-p
SMAD3 (rat) EVFAECLSDSAIFVQ S309
K378
TIRMSFVKGWGAEYR
1 4
SMAD3 (human) TIRMSFVkGWGAEYR K378-ac
SMAD3 (mouse) TIRMSFVKGWGAEYR K378
SMAD3 (rat) TIRMSFVKGWGAEYR K378
T388-p
GAEYRRQtVTSTPCW
Upstream
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Putative in vivo kinases:
  • PKG1 (mouse)
Treatment
  • KT5823
  • TGF-beta
SMAD3 (human) GAEYRRQtVTSTPCW T388-p
SMAD3 (mouse) GAEYRRQtVTSTPCW T388-p
SMAD3 (rat) GAEYRRQTVTSTPCW T388
T412
QWLDKVLTQMGSPSI
0 1
SMAD3 (human) QWLDKVLtQMGsPsI T412-p
SMAD3 (mouse) QWLDKVLTQMGSPSI T412
SMAD3 (rat) QWLDKVLTQMGSPSI T412
S416
KVLTQMGSPSIRCSs
1 3
SMAD3 (human) KVLtQMGsPsIRCss S416-p
SMAD3 (mouse) KVLTQMGSPSIRCSs S416
SMAD3 (rat) KVLTQMGSPSIRCSs S416
S418
LTQMGSPSIRCSsVs
2 1
SMAD3 (human) LtQMGsPsIRCssVs S418-p
SMAD3 (mouse) LTQMGSPSIRCSsVs S418
SMAD3 (rat) LTQMGSPSIRCSsVs S418
S422
GSPSIRCSsVs____
2 0
SMAD3 (human) GsPsIRCssVs____ S422-p
SMAD3 (mouse) GSPSIRCSsVs____ S422
SMAD3 (rat) GSPSIRCSsVs____ S422
S423-p
SPSIRCSsVs_____
Upstream
Downstream
24 5
SMAD3 (human)
S423-p
SMAD3 (mouse)
S423-p
SMAD3 (rat)
S423-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Regulatory protein:
  • caveolin-2 (mouse)
  • POSTN (mouse)
  • TDGF1 (mouse)
  • TGFB1 (mouse)
view more >
Treatment
  • bleomycin
  • hypoxia
  • nusinersen
  • SB431542
  • TGF-beta
view more >
SMAD3 (human) sPsIRCssVs_____ S423-p
SMAD3 (mouse) SPSIRCSsVs_____ S423-p
SMAD3 (rat) SPSIRCSsVs_____ S423-p
S425-p
SIRCSsVs_______
Upstream
Downstream
25 5
SMAD3 (human)
S425-p
SMAD3 (mouse)
S425-p
SMAD3 (rat)
S425-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Regulatory protein:
  • caveolin-2 (mouse)
  • POSTN (mouse)
  • TDGF1 (mouse)
  • TGFB1 (mouse)
view more >
Treatment
  • bleomycin
  • hypoxia
  • nusinersen
  • SB431542
  • TGF-beta
view more >
SMAD3 (human) sIRCssVs_______ S425-p
SMAD3 (mouse) SIRCSsVs_______ S425-p
SMAD3 (rat) SIRCSsVs_______ S425-p