CRYAB (mouse)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

S19-p

RPFFPFHsPsRLFDQ

Upstream

Downstream

Effects on Modified Protein

protein degradation

Regulatory protein:

KRas (mouse)
MKK6 (human)

Treatment

SB203580
virus infection

CRYAB (human)	RPFFPFHsPsrLFDQ	S19-p
CRYAB (mouse)	RPFFPFHsPsRLFDQ	S19-p
CRYAB (rat)	RPFFPFHsPSRLFDQ	S19-p
CRYAB (rabbit)	RPFFPFHsPsRLFDQ	S19-p
CRYAB (pig)	RPFFPFHSPSRLFDQ	S19
CRYAB (cow)	RPFFPFHsPsRLFDQ	S19-p

S21-p

FFPFHsPsRLFDQFF

CRYAB (human)	FFPFHsPsrLFDQFF	S21-p
CRYAB (mouse)	FFPFHsPsRLFDQFF	S21-p
CRYAB (rat)	FFPFHsPSRLFDQFF	S21
CRYAB (rabbit)	FFPFHsPsRLFDQFF	S21-p
CRYAB (pig)	FFPFHSPSRLFDQFF	S21
CRYAB (cow)	FFPFHsPsRLFDQFF	S21-p

R22

FPFHsPsRLFDQFFG

CRYAB (human)	FPFHsPsrLFDQFFG	R22-me
CRYAB (mouse)	FPFHsPsRLFDQFFG	R22
CRYAB (rat)	FPFHsPSRLFDQFFG	R22
CRYAB (rabbit)	FPFHsPsRLFDQFFG	R22
CRYAB (pig)	FPFHSPSRLFDQFFG	R22
CRYAB (cow)	FPFHsPsRLFDQFFG	R22

S35

FGEHLLESDLFSTAT

CRYAB (human)	FGEHLLESDLFPTST	S35
CRYAB (mouse)	FGEHLLESDLFSTAT	S35
CRYAB (rat)	FGEHLLESDLFSTAT	S35
CRYAB (rabbit)	FGEHLLESDLFPTST	S35
CRYAB (pig)	FGEHLLESDLFPAST	S35
CRYAB (cow)	FGEHLLEsDLFPAST	S35-p

S43

DLFSTATSLsPFYLR

CRYAB (human)	DLFPTSTsLsPFYLr	S43-p
CRYAB (mouse)	DLFSTATSLsPFYLR	S43
CRYAB (rat)	DLFSTATSLsPFYLR	S43
CRYAB (rabbit)	DLFPTSTSLsPFYLR	S43
CRYAB (pig)	DLFPASTSLSPFYFR	S43
CRYAB (cow)	DLFPASTsLsPFYLR	S43-p

S45-p

FSTATSLsPFYLRPP

Upstream

Downstream

Effects on Modified Protein

intracellular localization
molecular association, regulation
protein degradation

Effects on Biological Processes:

signaling pathway regulation

Putative in vivo kinases:

ERK1 (human)
PKN1 (mouse)

Regulatory protein:

MKK6 (human)
PKN1 (mouse)

Treatment

arsenite
heat_shock
ischemia/reperfusion
LPS
oxidative_stress
PD98059
SB203580
sorbitol
virus infection

CRYAB (human)	FPTSTsLsPFYLrPP	S45-p
CRYAB (mouse)	FSTATSLsPFYLRPP	S45-p
CRYAB (rat)	FSTATSLsPFYLRPP	S45-p
CRYAB (rabbit)	FPTSTSLsPFYLRPP	S45-p
CRYAB (pig)	FPASTSLSPFYFRPP	S45
CRYAB (cow)	FPASTsLsPFYLRPP	S45-p

R50

SLsPFYLRPPSFLRA

CRYAB (human)	sLsPFYLrPPsFLRA	R50-me
CRYAB (mouse)	SLsPFYLRPPSFLRA	R50
CRYAB (rat)	SLsPFYLRPPSFLRA	R50
CRYAB (rabbit)	SLsPFYLRPPSFLRA	R50
CRYAB (pig)	SLSPFYFRPPSFLRA	R50
CRYAB (cow)	sLsPFYLRPPsFLRA	R50

S53

PFYLRPPSFLRAPsW

CRYAB (human)	PFYLrPPsFLRAPsW	S53-p
CRYAB (mouse)	PFYLRPPSFLRAPsW	S53
CRYAB (rat)	PFYLRPPSFLRAPsW	S53
CRYAB (rabbit)	PFYLRPPSFLRAPsW	S53
CRYAB (pig)	PFYFRPPSFLRAPsW	S53
CRYAB (cow)	PFYLRPPsFLRAPsW	S53-p

S59-p

PSFLRAPsWIDtGLS

Upstream

Downstream

Effects on Modified Protein

intracellular localization
molecular association, regulation
protein degradation

Effects on Biological Processes:

apoptosis, inhibited
cytoskeletal reorganization
signaling pathway regulation

Putative in vivo kinases:

P38A (human)
P38A (mouse)
PKN1 (mouse)

Regulatory protein:

ADRB1 (mouse)
MKK6 (human)
PKN1 (mouse)

Treatment

arsenite
bisindolylmaleimide
cuprizone
cytochalasin_D
H-89
heat_shock
hyperoxia
ischemia/reperfusion
LPS
oxidative_stress
PD98059
PDGF
SB202190
SB203580
sorbitol
vinblastine
virus infection
Y27632

CRYAB (human)	PsFLRAPsWFDTGLS	S59-p
CRYAB (mouse)	PSFLRAPsWIDtGLS	S59-p
CRYAB (rat)	PSFLRAPsWIDTGLS	S59-p
CRYAB (rabbit)	PSFLRAPsWIDTGLS	S59-p
CRYAB (pig)	PSFLRAPsWIDTGLS	S59-p
CRYAB (cow)	PsFLRAPsWIDTGLS	S59-p

T63-p

RAPsWIDtGLSEMRL

CRYAB (human)	RAPsWFDTGLSEMRL	T63
CRYAB (mouse)	RAPsWIDtGLSEMRL	T63-p
CRYAB (rat)	RAPsWIDTGLSEMRM	T63
CRYAB (rabbit)	RAPsWIDTGLSEMRL	T63
CRYAB (pig)	RAPsWIDTGLSEMRL	T63
CRYAB (cow)	RAPsWIDTGLSEMRL	T63

K72-ub

LSEMRLEkDRFSVNL

CRYAB (human)	LSEMRLEKDrFsVNL	K72
CRYAB (mouse)	LSEMRLEkDRFSVNL	K72-ub
CRYAB (rat)	LSEMRMEKDRFSVNL	K72
CRYAB (rabbit)	LSEMRLEKDRFSVNL	K72
CRYAB (pig)	LSEMRLEKDRFSVNL	K72
CRYAB (cow)	LSEMRLEKDRFsVNL	K72

R74

EMRLEkDRFSVNLDV

CRYAB (human)	EMRLEKDrFsVNLDV	R74-m1
CRYAB (mouse)	EMRLEkDRFSVNLDV	R74
CRYAB (rat)	EMRMEKDRFSVNLDV	R74
CRYAB (rabbit)	EMRLEKDRFSVNLDV	R74
CRYAB (pig)	EMRLEKDRFSVNLDV	R74
CRYAB (cow)	EMRLEKDRFsVNLDV	R74

S76

RLEkDRFSVNLDVkH

CRYAB (human)	RLEKDrFsVNLDVkH	S76-p
CRYAB (mouse)	RLEkDRFSVNLDVkH	S76
CRYAB (rat)	RMEKDRFSVNLDVkH	S76
CRYAB (rabbit)	RLEKDRFSVNLDVKH	S76
CRYAB (pig)	RLEKDRFSVNLDVKH	S76
CRYAB (cow)	RLEKDRFsVNLDVKH	S76-p

K82-ub

FSVNLDVkHFSPEEL

CRYAB (human)	FsVNLDVkHFsPEEL	K82-ub
CRYAB (mouse)	FSVNLDVkHFSPEEL	K82-ub
CRYAB (rat)	FSVNLDVKHFSPEEL	K82
CRYAB (rabbit)	FSVNLDVKHFSPEEL	K82
CRYAB (pig)	FSVNLDVKHFSPEEL	K82
CRYAB (cow)	FsVNLDVKHFsPEEL	K82

K82

FSVNLDVKHFSPEEL

CRYAB (human)	FsVNLDVKHFsPEEL	K82
CRYAB (mouse)	FSVNLDVKHFSPEEL	K82
CRYAB (rat)	FSVNLDVkHFSPEEL	K82-ac
CRYAB (rabbit)	FSVNLDVKHFSPEEL	K82
CRYAB (pig)	FSVNLDVKHFSPEEL	K82
CRYAB (cow)	FsVNLDVKHFsPEEL	K82

S85

NLDVkHFSPEELkVk

CRYAB (human)	NLDVkHFsPEELkVk	S85-p
CRYAB (mouse)	NLDVkHFSPEELkVk	S85
CRYAB (rat)	NLDVkHFSPEELkVK	S85
CRYAB (rabbit)	NLDVKHFSPEELKVK	S85
CRYAB (pig)	NLDVKHFSPEELKVK	S85
CRYAB (cow)	NLDVKHFsPEELkVk	S85-p

K90

HFSPEELKVkVLGDV

CRYAB (human)	HFsPEELkVkVLGDV	K90-ac
CRYAB (mouse)	HFSPEELKVkVLGDV	K90
CRYAB (rat)	HFSPEELkVKVLGDV	K90-ac
CRYAB (rabbit)	HFSPEELKVKVLGDV	K90
CRYAB (pig)	HFSPEELKVKVLGDV	K90
CRYAB (cow)	HFsPEELkVkVLGDV	K90-ac

K90-ub

HFSPEELkVkVLGDV

CRYAB (human)	HFsPEELkVkVLGDV	K90-ub
CRYAB (mouse)	HFSPEELkVkVLGDV	K90-ub
CRYAB (rat)	HFSPEELKVKVLGDV	K90
CRYAB (rabbit)	HFSPEELKVKVLGDV	K90
CRYAB (pig)	HFSPEELKVKVLGDV	K90
CRYAB (cow)	HFsPEELKVkVLGDV	K90

K92

SPEELkVKVLGDVIE

CRYAB (human)	sPEELkVkVLGDVIE	K92-ac
CRYAB (mouse)	SPEELkVKVLGDVIE	K92
CRYAB (rat)	SPEELkVKVLGDVIE	K92
CRYAB (rabbit)	SPEELKVKVLGDVIE	K92
CRYAB (pig)	SPEELKVKVLGDVIE	K92
CRYAB (cow)	sPEELkVkVLGDVIE	K92-ac

K92-ub

SPEELkVkVLGDVIE

CRYAB (human)	sPEELkVkVLGDVIE	K92-ub
CRYAB (mouse)	SPEELkVkVLGDVIE	K92-ub
CRYAB (rat)	SPEELkVKVLGDVIE	K92
CRYAB (rabbit)	SPEELKVKVLGDVIE	K92
CRYAB (pig)	SPEELKVKVLGDVIE	K92
CRYAB (cow)	sPEELkVKVLGDVIE	K92

K103-ub

DVIEVHGkHEERQDE

CRYAB (human)	DVIEVHGKHEERQDE	K103
CRYAB (mouse)	DVIEVHGkHEERQDE	K103-ub
CRYAB (rat)	DVIEVHGKHEERQDE	K103
CRYAB (rabbit)	DVIEVHGKHEERQDE	K103
CRYAB (pig)	DVIEVHGKHEERQDE	K103
CRYAB (cow)	DVIEVHGKHEERQDE	K103

K103

DVIEVHGKHEERQDE

CRYAB (human)	DVIEVHGKHEERQDE	K103
CRYAB (mouse)	DVIEVHGKHEERQDE	K103
CRYAB (rat)	DVIEVHGkHEERQDE	K103-ac
CRYAB (rabbit)	DVIEVHGKHEERQDE	K103
CRYAB (pig)	DVIEVHGKHEERQDE	K103
CRYAB (cow)	DVIEVHGKHEERQDE	K103

T132

PADVDPLTITSSLSS

CRYAB (human)	PADVDPLtItssLSS	T132-p
CRYAB (mouse)	PADVDPLTITSSLSS	T132
CRYAB (rat)	PADVDPLTITSSLSS	T132
CRYAB (rabbit)	PADVDPLTITSSLSS	T132
CRYAB (pig)	PADVDPLTITSSLSS	T132
CRYAB (cow)	PADVDPLAITSSLSS	A132

T134

DVDPLTITSSLSSDG

CRYAB (human)	DVDPLtItssLSSDG	T134-p
CRYAB (mouse)	DVDPLTITSSLSSDG	T134
CRYAB (rat)	DVDPLTITSSLSSDG	T134
CRYAB (rabbit)	DVDPLTITSSLSSDG	T134
CRYAB (pig)	DVDPLTITSSLSSDG	T134
CRYAB (cow)	DVDPLAITSSLSSDG	T134

S135

VDPLTITSSLSSDGV

CRYAB (human)	VDPLtItssLSSDGV	S135-p
CRYAB (mouse)	VDPLTITSSLSSDGV	S135
CRYAB (rat)	VDPLTITSSLSSDGV	S135
CRYAB (rabbit)	VDPLTITSSLSSDGV	S135
CRYAB (pig)	VDPLTITSSLSSDGV	S135
CRYAB (cow)	VDPLAITSSLSSDGV	S135

S136

DPLTITSSLSSDGVL

CRYAB (human)	DPLtItssLSSDGVL	S136-p
CRYAB (mouse)	DPLTITSSLSSDGVL	S136
CRYAB (rat)	DPLTITSSLSSDGVL	S136
CRYAB (rabbit)	DPLTITSSLSSDGVL	S136
CRYAB (pig)	DPLTITSSLSSDGVL	S136
CRYAB (cow)	DPLAITSSLSSDGVL	S136

T144

LSSDGVLTVNGPRkQ

CRYAB (human)	LSSDGVLtVNGPRkQ	T144-p
CRYAB (mouse)	LSSDGVLTVNGPRkQ	T144
CRYAB (rat)	LSSDGVLTVNGPRKQ	T144
CRYAB (rabbit)	LSSDGVLTVNGPRKQ	T144
CRYAB (pig)	LSSDGVLTVNGPRRQ	T144
CRYAB (cow)	LSSDGVLTVNGPRkQ	T144

K150-ub

LTVNGPRkQVSGPER

CRYAB (human)	LtVNGPRkQVSGPER	K150-ub
CRYAB (mouse)	LTVNGPRkQVSGPER	K150-ub
CRYAB (rat)	LTVNGPRKQASGPER	K150
CRYAB (rabbit)	LTVNGPRKQAPGPER	K150
CRYAB (pig)	LTVNGPRRQASGPER	R150
CRYAB (cow)	LTVNGPRKQAsGPER	K150

K150

LTVNGPRKQVSGPER

CRYAB (human)	LtVNGPRKQVSGPER	K150
CRYAB (mouse)	LTVNGPRKQVSGPER	K150
CRYAB (rat)	LTVNGPRKQASGPER	K150
CRYAB (rabbit)	LTVNGPRKQAPGPER	K150
CRYAB (pig)	LTVNGPRRQASGPER	R150
CRYAB (cow)	LTVNGPRkQAsGPER	K150-ac

S153

NGPRkQVSGPERtIP

CRYAB (human)	NGPRkQVSGPERtIP	S153
CRYAB (mouse)	NGPRkQVSGPERtIP	S153
CRYAB (rat)	NGPRKQASGPERTIP	S153
CRYAB (rabbit)	NGPRKQAPGPERTIP	P153
CRYAB (pig)	NGPRRQASGPERTIP	S153
CRYAB (cow)	NGPRkQAsGPERTIP	S153-p

T158-p

QVSGPERtIPItREE

CRYAB (human)	QVSGPERtIPITREE	T158-p
CRYAB (mouse)	QVSGPERtIPItREE	T158-p
CRYAB (rat)	QASGPERTIPITREE	T158
CRYAB (rabbit)	QAPGPERTIPITREE	T158
CRYAB (pig)	QASGPERTIPITREE	T158
CRYAB (cow)	QAsGPERTIPItREE	T158

T162-gl

PERtIPItREEkPAV

CRYAB (human)	PERtIPITREEkPAV	T162
CRYAB (mouse)	PERtIPItREEkPAV	T162-gl
CRYAB (rat)	PERTIPITREEkPAV	T162
CRYAB (rabbit)	PERTIPITREEKPAV	T162
CRYAB (pig)	PERTIPITREEKPAV	T162
CRYAB (cow)	PERTIPItREEkPAV	T162-gl

K166-ub

IPItREEkPAVAAAP

CRYAB (human)	IPITREEkPAVtAAP	K166-ub
CRYAB (mouse)	IPItREEkPAVAAAP	K166-ub
CRYAB (rat)	IPITREEKPAVtAAP	K166
CRYAB (rabbit)	IPITREEKPAVTAAP	K166
CRYAB (pig)	IPITREEKPAVTAAP	K166
CRYAB (cow)	IPItREEKPAVtAAP	K166

K166

IPItREEKPAVAAAP

CRYAB (human)	IPITREEkPAVtAAP	K166-ac
CRYAB (mouse)	IPItREEKPAVAAAP	K166
CRYAB (rat)	IPITREEkPAVtAAP	K166-ac
CRYAB (rabbit)	IPITREEKPAVTAAP	K166
CRYAB (pig)	IPITREEKPAVTAAP	K166
CRYAB (cow)	IPItREEkPAVtAAP	K166-ac

A170

REEkPAVAAAPkk__

CRYAB (human)	REEkPAVtAAPKK__	T170-gl
CRYAB (mouse)	REEkPAVAAAPkk__	A170
CRYAB (rat)	REEkPAVtAAPKK__	T170-gl
CRYAB (rabbit)	REEKPAVTAAPKK__	T170
CRYAB (pig)	REEKPAVTAAPKK__	T170
CRYAB (cow)	REEkPAVtAAPKK__	T170-gl

K174-ub

PAVAAAPkk______

CRYAB (human)	PAVtAAPKK______	K174
CRYAB (mouse)	PAVAAAPkk______	K174-ub
CRYAB (rat)	PAVtAAPKK______	K174
CRYAB (rabbit)	PAVTAAPKK______	K174
CRYAB (pig)	PAVTAAPKK______	K174
CRYAB (cow)	PAVtAAPKK______	K174

K175-ub

AVAAAPkk_______

CRYAB (human)	AVtAAPKK_______	K175
CRYAB (mouse)	AVAAAPkk_______	K175-ub
CRYAB (rat)	AVtAAPKK_______	K175
CRYAB (rabbit)	AVTAAPKK_______	K175
CRYAB (pig)	AVTAAPKK_______	K175
CRYAB (cow)	AVtAAPKK_______	K175