Other Species / Isoforms
  ubiquitin (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K6-ac
__MQIFVktLTGktI
Upstream
Downstream
5 13
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Treatment
  • MC1658
  • MS275
  • nicotinamide
  • trichostatin_A
view more >
ubiquitin (human) __MQIFVktLTGktI K6-ac
ubiquitin (mouse) __MQIFVktLTGkTI K6-ac
ubiquitin (rat) __MQIFVKTLTGkTI K6
ubiquitin (cow) __MQIFVKTLTGKTI K6
K6-ub
__MQIFVktLTGktI
Downstream
16 173
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, induced
ubiquitin (human) __MQIFVktLTGktI K6-ub
ubiquitin (mouse) __MQIFVktLTGkTI K6-ub
ubiquitin (rat) __MQIFVKTLTGkTI K6
ubiquitin (cow) __MQIFVkTLTGKTI K6-ub
T7-p
_MQIFVktLTGktIt
0 5
ubiquitin (human) _MQIFVktLTGktIt T7-p
ubiquitin (mouse) _MQIFVktLTGkTIt T7-p
ubiquitin (rat) _MQIFVKTLTGkTIT T7
ubiquitin (cow) _MQIFVkTLTGKTIT T7
K11-ub
FVktLTGktItLEVE
Upstream
Downstream
23 176
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • signaling pathway regulation
  • transcription, induced
Treatment
  • UV
ubiquitin (human) FVktLTGktItLEVE K11-ub
ubiquitin (mouse) FVktLTGkTItLEVE K11-ub
ubiquitin (rat) FVKTLTGKTITLEVE K11
ubiquitin (cow) FVkTLTGKTITLEVE K11
K11-sm
FVktLTGktItLEVE
Upstream
0 4
Treatment
  • As2O3
ubiquitin (human) FVktLTGktItLEVE K11-sm
ubiquitin (mouse) FVktLTGkTItLEVE K11-sm
ubiquitin (rat) FVKTLTGKTITLEVE K11
ubiquitin (cow) FVkTLTGKTITLEVE K11
T12-p
VktLTGktItLEVEP
0 3
ubiquitin (human) VktLTGktItLEVEP T12-p
ubiquitin (mouse) VktLTGkTItLEVEP T12
ubiquitin (rat) VKTLTGkTITLEVEP T12
ubiquitin (cow) VkTLTGKTITLEVEP T12
T14-p
tLTGktItLEVEPsD
1 4
ubiquitin (human) tLTGktItLEVEPsD T14-p
ubiquitin (mouse) tLTGkTItLEVEPsD T14-p
ubiquitin (rat) TLTGkTITLEVEPsD T14
ubiquitin (cow) TLTGKTITLEVEPSD T14
S20-p
ItLEVEPsDtIENVk
Downstream
1 7
Effects on Modified Protein
  • enzymatic activity, induced
ubiquitin (human) ItLEVEPsDtIENVk S20-p
ubiquitin (mouse) ItLEVEPsDTIENVk S20-p
ubiquitin (rat) ITLEVEPsDTIENVk S20-p
ubiquitin (cow) ITLEVEPSDTIENVK S20
S20-ub
ItLEVEPsDtIENVk
0 1
ubiquitin (human) ItLEVEPsDtIENVk S20-ub
ubiquitin (mouse) ItLEVEPSDTIENVk S20
ubiquitin (rat) ITLEVEPSDTIENVk S20
ubiquitin (cow) ITLEVEPSDTIENVK S20
T22-p
LEVEPsDtIENVkAk
0 1
ubiquitin (human) LEVEPsDtIENVkAk T22-p
ubiquitin (mouse) LEVEPsDTIENVkAk T22
ubiquitin (rat) LEVEPsDTIENVkAK T22
ubiquitin (cow) LEVEPSDTIENVKAK T22
T22-ub
LEVEPsDtIENVkAk
0 1
ubiquitin (human) LEVEPsDtIENVkAk T22-ub
ubiquitin (mouse) LEVEPsDTIENVkAk T22
ubiquitin (rat) LEVEPsDTIENVkAK T22
ubiquitin (cow) LEVEPSDTIENVKAK T22
K27-ac
sDtIENVkAkIQDkE
3 1
ubiquitin (human) sDtIENVkAkIQDkE K27-ac
ubiquitin (mouse) sDTIENVKAkIQDkE K27
ubiquitin (rat) sDTIENVkAKIQDkE K27-ac
ubiquitin (cow) SDTIENVKAKIQDKE K27
K11-ac
FVktLTGktItLEVE
3 3
ubiquitin (human) FVktLTGktItLEVE K11-ac
ubiquitin (mouse) FVktLTGKTItLEVE K11
ubiquitin (rat) FVKTLTGkTITLEVE K11-ac
ubiquitin (cow) FVkTLTGKTITLEVE K11
K27-ub
sDtIENVkAkIQDkE
Upstream
Downstream
30 164
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, induced
  • autophagy, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell differentiation, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, induced
  • transcription, inhibited
Treatment
  • high_glucose
  • MG132
  • sorbitol
  • triptolide
view more >
ubiquitin (human) sDtIENVkAkIQDkE K27-ub
ubiquitin (mouse) sDTIENVkAkIQDkE K27-ub
ubiquitin (rat) sDTIENVKAKIQDkE K27
ubiquitin (cow) SDTIENVKAKIQDKE K27
K29-ac
tIENVkAkIQDkEGI
3 1
ubiquitin (human) tIENVkAkIQDkEGI K29-ac
ubiquitin (mouse) TIENVkAKIQDkEGI K29
ubiquitin (rat) TIENVkAKIQDkEGI K29
ubiquitin (cow) TIENVKAKIQDKEGI K29
K29-ub
tIENVkAkIQDkEGI
Downstream
18 157
Effects on Modified Protein
  • activity, induced
  • protein conformation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • cell growth, induced
  • cell growth, inhibited
  • endocytosis, induced
  • transcription, induced
  • transcription, inhibited
ubiquitin (human) tIENVkAkIQDkEGI K29-ub
ubiquitin (mouse) TIENVkAkIQDkEGI K29-ub
ubiquitin (rat) TIENVkAKIQDkEGI K29
ubiquitin (cow) TIENVKAKIQDKEGI K29
K33-ac
VkAkIQDkEGIPPDQ
3 3
ubiquitin (human) VkAkIQDkEGIPPDQ K33-ac
ubiquitin (mouse) VkAkIQDkEGIPPDQ K33-ac
ubiquitin (rat) VkAKIQDkEGIPPDQ K33-ac
ubiquitin (cow) VKAKIQDKEGIPPDQ K33
K33-ub
VkAkIQDkEGIPPDQ
Downstream
13 149
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • exocytosis, induced
  • signaling pathway regulation
ubiquitin (human) VkAkIQDkEGIPPDQ K33-ub
ubiquitin (mouse) VkAkIQDkEGIPPDQ K33-ub
ubiquitin (rat) VkAKIQDKEGIPPDQ K33
ubiquitin (cow) VKAKIQDKEGIPPDQ K33
K48-ac
QRLIFAGkQLEDGRT
Upstream
Downstream
6 6
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Treatment
  • MC1658
  • MS275
  • nicotinamide
  • trichostatin_A
  • vorinostat
view more >
ubiquitin (human) QRLIFAGkQLEDGRT K48-ac
ubiquitin (mouse) QRLIFAGkQLEDGRT K48-ac
ubiquitin (rat) QRLIFAGkQLEDGRT K48-ac
ubiquitin (cow) QRLIFAGKQLEDGRT K48
K48-ub
QRLIFAGkQLEDGRT
Upstream
Downstream
124 211
ubiquitin (human)
K48-ub
ubiquitin (mouse)
K48-ub
ubiquitin (rat)
K48-ub
ubiquitin (cow)
K48-ub
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, altered
  • apoptosis, induced
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell differentiation, induced
  • cell growth, altered
  • cell growth, induced
  • cell growth, inhibited
  • cell motility, inhibited
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Regulatory protein:
  • CCND1 (human)
  • MDM2 (human)
  • NLRP11 (human)
  • TRAF3IP3 (human)
  • USP1 (human)
  • VCP (human)
view more >
Treatment
  • bergenin
  • IL-1a
  • LPS
  • MG132
  • NaAsO2
  • nigericin
  • siRNA
  • TNF
  • UV
  • vorinostat
view more >
ubiquitin (human) QRLIFAGkQLEDGRT K48-ub
ubiquitin (mouse) QRLIFAGkQLEDGRT K48-ub
ubiquitin (rat) QRLIFAGKQLEDGRT K48
ubiquitin (cow) QRLIFAGKQLEDGRT K48
S57-p
LEDGRTLsDyNIQkE
Upstream
Downstream
1 30
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • metformin
ubiquitin (human) LEDGRTLsDyNIQkE S57-p
ubiquitin (mouse) LEDGRTLsDYNIQkE S57-p
ubiquitin (rat) LEDGRTLsDYNIQkE S57-p
ubiquitin (cow) LEDGRTLSDYNIQkE S57
Y59-p
DGRTLsDyNIQkEst
0 14
ubiquitin (human) DGRTLsDyNIQkEst Y59-p
ubiquitin (mouse) DGRTLsDYNIQkEst Y59
ubiquitin (rat) DGRTLsDYNIQkEsT Y59
ubiquitin (cow) DGRTLSDYNIQkEST Y59
K63-ac
LsDyNIQkEstLHLV
6 4
ubiquitin (human) LsDyNIQkEstLHLV K63-ac
ubiquitin (mouse) LsDYNIQkEstLHLV K63-ac
ubiquitin (rat) LsDYNIQkEsTLHLV K63-ac
ubiquitin (cow) LSDYNIQKESTLHLV K63
K63-ub
LsDyNIQkEstLHLV
Upstream
Downstream
130 200
ubiquitin (human)
K63-ub
ubiquitin (mouse)
K63-ub
ubiquitin (rat)
K63-ub
ubiquitin (cow)
K63-ub
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • protein stabilization
  • receptor internalization, induced
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, induced
  • DNA repair, inhibited
  • apoptosis, induced
  • apoptosis, inhibited
  • autophagy, induced
  • autophagy, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell adhesion, induced
  • cell cycle regulation
  • cell differentiation, induced
  • cell growth, altered
  • cell growth, induced
  • cell growth, inhibited
  • cell motility, induced
  • cell motility, inhibited
  • endocytosis, induced
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Regulatory protein:
  • BARD1 (human)
  • beclin 1 (human)
  • BRCA1 (human)
  • CALML6 (human)
  • CYLD (human)
  • GCA (human)
  • MDM2 (human)
  • SHIP (human)
  • TAK1 (human)
  • TNFSF11 (human)
  • TRAF2 (human)
view more >
Treatment
  • antigenic stimulation
  • arginine deprivation
  • dynorphin_A
  • IL-1a
  • IL-1b
  • MLN4924
  • NaAsO2
  • nigericin
  • NSC697923
  • ramipril
  • serum
  • siRNA
  • TNF
  • U50488
  • UV
  • vorinostat
view more >
ubiquitin (human) LsDyNIQkEstLHLV K63-ub
ubiquitin (mouse) LsDYNIQkEstLHLV K63-ub
ubiquitin (rat) LsDYNIQKEsTLHLV K63
ubiquitin (cow) LSDYNIQkESTLHLV K63-ub
K63-sm
LsDyNIQkEstLHLV
0 4
ubiquitin (human) LsDyNIQkEstLHLV K63-sm
ubiquitin (mouse) LsDYNIQkEstLHLV K63-sm
ubiquitin (rat) LsDYNIQKEsTLHLV K63
ubiquitin (cow) LSDYNIQKESTLHLV K63
S65-p
DyNIQkEstLHLVLR
Upstream
Downstream
27 17
ubiquitin (human)
S65-p
ubiquitin (mouse)
S65-p
ubiquitin (rat)
S65-p
ubiquitin (cow)
S65-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
Kinase, in vitro:
  • PINK1 (human)
Putative in vivo kinases:
  • PINK1 (human)
Putative upstream phosphatases:
  • PPEF2 (human)
Regulatory protein:
  • JUB (human)
  • PARK2 (human)
  • PINK1 (human)
view more >
Treatment
  • CCCP
  • mono-2-ethylhexyl phthalate
  • siRNA
  • stress
view more >
ubiquitin (human) DyNIQkEstLHLVLR S65-p
ubiquitin (mouse) DYNIQkEstLHLVLR S65-p
ubiquitin (rat) DYNIQkEsTLHLVLR S65-p
ubiquitin (cow) DYNIQkESTLHLVLR S65
T66-p
yNIQkEstLHLVLRL
Upstream
2 3
Kinase, in vitro:
  • PINK1 (human)
ubiquitin (human) yNIQkEstLHLVLRL T66-p
ubiquitin (mouse) YNIQkEstLHLVLRL T66-p
ubiquitin (rat) YNIQkEsTLHLVLRL T66
ubiquitin (cow) YNIQkESTLHLVLRL T66