Other Species / Isoforms
  CBL (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K7-ub
_MAGNVKksSGAGGG
0 5
CBL (human) _MAGNVKksSGAGGG K7-ub
CBL (mouse) _MAGNVKKSSGAGGG K7
CBL (rat) _MAGNVKKSSGAGGS K7
S8-p
MAGNVKksSGAGGGs
0 1
CBL (human) MAGNVKksSGAGGGs S8-p
CBL (mouse) MAGNVKKSSGAGGGG S8
CBL (rat) MAGNVKKSSGAGGSG S8
S15-p
sSGAGGGsGsGGsGs
0 1
CBL (human) sSGAGGGsGsGGsGs S15-p
CBL (mouse) gap -
CBL (rat) KSSGAGGSGSGGSGA S14
S17-p
GAGGGsGsGGsGsGG
0 2
CBL (human) GAGGGsGsGGsGsGG S17-p
CBL (mouse) SGAGGGGSGGSGAGG S16
CBL (rat) SGAGGSGSGGSGAGG S16
S20-p
GGsGsGGsGsGGLIG
0 1
CBL (human) GGsGsGGsGsGGLIG S20-p
CBL (mouse) GGGGSGGSGAGGLIG S19
CBL (rat) GGSGSGGSGAGGLIG S19
S22-p
sGsGGsGsGGLIGLM
0 1
CBL (human) sGsGGsGsGGLIGLM S22-p
CBL (mouse) GGSGGSGAGGLIGLM A21
CBL (rat) SGSGGSGAGGLIGLM A21
K58-ub
VDKKMVEkCWKLMDK
0 1
CBL (human) VDKKMVEkCWKLMDK K58-ub
CBL (mouse) VDKKMVEKCWKLMDK K56
CBL (rat) VDKKMVEKCWKLMDK K57
K74-ub
VRLCQNPkLALKNSP
0 3
CBL (human) VRLCQNPkLALKNSP K74-ub
CBL (mouse) VRLCQNPKLALKNSP K72
CBL (rat) VRLCQNPKLALKNSP K73
K105-ub
ILSRYEGkMETLGEN
0 1
CBL (human) ILSRYEGkMETLGEN K105-ub
CBL (mouse) VLSRYEGKMETLGEN K103
CBL (rat) VLSRYEGKMETLGEN K104
T126-p
MENLMKKtKQTISLF
0 1
CBL (human) MENLMKKtKQTISLF T126-p
CBL (mouse) MENLMKKTKQTISLF T124
CBL (rat) MENLMKKTKQTISLF T125
K134-ac
KQTISLFkEGKERMy
0 2
CBL (human) KQTISLFkEGKERMy K134-ac
CBL (mouse) KQTISLFKEGKERMY K132
CBL (rat) KQTISLFKEGKERMY K133
Y141-p
kEGKERMyEENSQPR
0 17
CBL (human) kEGKERMyEENSQPR Y141-p
CBL (mouse) KEGKERMYEENSQPR Y139
CBL (rat) KEGKERMYEENSQPR Y140
K197-ac
WRKAFGEkTIVPWkS
0 1
CBL (human) WRKAFGEkTIVPWkS K197-ac
CBL (mouse) WRKAFGEKTIVPWkS K195
CBL (rat) WRKAFGEKTIVPWKS K196
K203-ub
EkTIVPWkSFRQALH
0 8
CBL (human) EkTIVPWkSFRQALH K203-ub
CBL (mouse) EKTIVPWkSFRQALH K201-ub
CBL (rat) EKTIVPWKSFRQALH K202
Y368-p
IKVTQEQyELyCEMG
Downstream
1 5
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein conformation
CBL (human) IKVTQEQyELyCEMG Y368-p
CBL (mouse) IKVTQEQYELYCEMG Y366
CBL (rat) IKVTQEQYELYCEMG Y367
Y371-p
TQEQyELyCEMGSTF
Upstream
Downstream
7 89
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell growth, altered
  • signaling pathway regulation
Putative in vivo kinases:
  • EGFR (mouse)
  • INSR (rat)
  • LYN (human)
Treatment
  • EGF
  • insulin
  • PP2
CBL (human) TQEQyELyCEMGSTF Y371-p
CBL (mouse) TQEQYELYCEMGSTF Y369
CBL (rat) TQEQYELYCEMGSTF Y370
K424-ub
PFCRCEIkGTEPIVV
0 7
CBL (human) PFCRCEIkGTEPIVV K424-ub
CBL (mouse) PFCRCEIKGTEPIVV K422
CBL (rat) PFCRCEIKGTEPIVV K423
S439-p
DPFDPRGsGsLLRQG
0 3
CBL (human) DPFDPRGsGsLLRQG S439-p
CBL (mouse) DPFDPRGSGsLLRQG S437
CBL (rat) DPFDPRGSGSLLRQG S438
S441-p
FDPRGsGsLLRQGAE
0 4
CBL (human) FDPRGsGsLLRQGAE S441-p
CBL (mouse) FDPRGSGsLLRQGAE S439-p
CBL (rat) FDPRGSGSLLRQGAE S440
S452-p
QGAEGAPsPNyDDDD
0 14
CBL (human) QGAEGAPsPNyDDDD S452-p
CBL (mouse) QGAEGAPsPNyDDDD S450-p
CBL (rat) QGAEGAPsPNYDDDD S451-p
Y455-p
EGAPsPNyDDDDDER
Upstream
0 35
Treatment
  • HGF
CBL (human) EGAPsPNyDDDDDER Y455-p
CBL (mouse) EGAPsPNyDDDDDER Y453-p
CBL (rat) EGAPsPNYDDDDDER Y454
P482
GAKVERPPsPFsMAP
0 4
CBL (human) GAKVERPPsPFsMAP P482
CBL (mouse) GAKVERPssPFsMAP S480-p
CBL (rat) GAKVERPSSPFSMAP S481
S483-p
AKVERPPsPFsMAPQ
Upstream
0 23
Treatment
  • SII_angiotensin_2
CBL (human) AKVERPPsPFsMAPQ S483-p
CBL (mouse) AKVERPssPFsMAPQ S481-p
CBL (rat) AKVERPSSPFSMAPQ S482
S486-p
ERPPsPFsMAPQAsL
0 13
CBL (human) ERPPsPFsMAPQAsL S486-p
CBL (mouse) ERPssPFsMAPQASL S484-p
CBL (rat) ERPSSPFSMAPQASL S485
S492-p
FsMAPQAsLPPVPPR
0 3
CBL (human) FsMAPQAsLPPVPPR S492-p
CBL (mouse) FsMAPQASLPPVPPR S490
CBL (rat) FSMAPQASLPPVPPR S491
R506
RLDLLPQRVCVPssA
0 3
CBL (human) RLDLLPQRVCVPssA R506
CBL (mouse) RLDLLQQRAPVPAST R504
CBL (rat) RLDLLQQrAPVPAST R505-m1
S511-p
PQRVCVPssAsALGT
0 1
CBL (human) PQRVCVPssAsALGT S511-p
CBL (mouse) QQRAPVPASTSVLGT A509
CBL (rat) QQrAPVPASTSVLGT A510
S512-p
QRVCVPssAsALGTA
0 1
CBL (human) QRVCVPssAsALGTA S512-p
CBL (mouse) QRAPVPASTSVLGTA S510
CBL (rat) QrAPVPASTSVLGTA S511
S514-p
VCVPssAsALGTAsk
0 1
CBL (human) VCVPssAsALGTAsk S514-p
CBL (mouse) APVPASTSVLGTASK S512
CBL (rat) APVPASTSVLGTASK S513
S520-p
AsALGTAskAASGSL
0 1
CBL (human) AsALGTAskAASGSL S520-p
CBL (mouse) TSVLGTASKAASGSL S518
CBL (rat) TSVLGTASKASSSSL S519
K521-ub
sALGTAskAASGSLH
0 2
CBL (human) sALGTAskAASGSLH K521-ub
CBL (mouse) SVLGTASKAASGSLH K519
CBL (rat) SVLGTASKASSSSLH K520
Y552-p
PPPPDRPySVGAESR
Upstream
0 5
Treatment
  • EGF
CBL (human) PPPPDRPySVGAESR Y552-p
CBL (mouse) PPPPDRPYSVGAETR Y550
CBL (rat) PPPPDRPYSVGTETR Y551
T568-p
QRRPLPCtPGDCPSR
0 9
CBL (human) QRRPLPCtPGDCPSR T568-p
CBL (mouse) QRRPLPCTPGDCPSR T566
CBL (rat) QRRPLPCTPGDCPSR T567
K577-ub
GDCPSRDkLPPVPss
0 2
CBL (human) GDCPSRDkLPPVPss K577-ub
CBL (mouse) GDCPSRDKLPPVPSS K575
CBL (rat) GDCPSRDKLPPVPSS K576
S583-p
DkLPPVPssRLGDsW
0 1
CBL (human) DkLPPVPssRLGDsW S583-p
CBL (mouse) DKLPPVPSSRPGDSW S581
CBL (rat) DKLPPVPSSRPGDSW S582
S584-p
kLPPVPssRLGDsWL
0 1
CBL (human) kLPPVPssRLGDsWL S584-p
CBL (mouse) KLPPVPSSRPGDSWL S582
CBL (rat) KLPPVPSSRPGDSWL S583
S589-p
PssRLGDsWLPRPIP
0 2
CBL (human) PssRLGDsWLPRPIP S589-p
CBL (mouse) PSSRPGDSWLSRPIP S587
CBL (rat) PSSRPGDSWLSRPIP S588
S601-p
PIPKVPVsAPSSSDP
0 2
CBL (human) PIPKVPVsAPSSSDP S601-p
CBL (mouse) PIPKVPVATPNPGDP A599
CBL (rat) PIPKVPVATPNPGDP A600
S619-p
RELTNRHsLPFsLPS
Upstream
Downstream
1 29
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • ischemia
CBL (human) RELTNRHsLPFsLPS S619-p
CBL (mouse) RELTNRHsLPFsLPS S617-p
CBL (rat) RELTNRHSLPFSLPS S618
S623-p
NRHsLPFsLPSQMEP
Downstream
1 3
Effects on Modified Protein
  • molecular association, regulation
CBL (human) NRHsLPFsLPSQMEP S623-p
CBL (mouse) NRHsLPFsLPSQMEP S621-p
CBL (rat) NRHSLPFSLPSQMEP S622
S639-p
PDVPRLGstFsLDts
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
CBL (human) PDVPRLGstFsLDts S639-p
CBL (mouse) ADVPRLGsTFsLDTS S637-p
CBL (rat) ADVPRLGSTFSLDTS S638
T640-p
DVPRLGstFsLDtsM
Upstream
Downstream
1 2
Effects on Modified Protein
  • neddylation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • cell growth, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • adriamycin
  • KU-55933
  • MMS
CBL (human) DVPRLGstFsLDtsM T640-p
CBL (mouse) DVPRLGsTFsLDTSM T638
CBL (rat) DVPRLGSTFSLDTST T639
S642-p
PRLGstFsLDtsMSM
Downstream
1 11
Effects on Modified Protein
  • molecular association, regulation
CBL (human) PRLGstFsLDtsMSM S642-p
CBL (mouse) PRLGsTFsLDTSMTM S640-p
CBL (rat) PRLGSTFSLDTSTTM S641
T645-p
GstFsLDtsMSMNSs
0 1
CBL (human) GstFsLDtsMSMNSs T645-p
CBL (mouse) GsTFsLDTSMTMNSS T643
CBL (rat) GSTFSLDTSTTMNSS T644
S646-p
stFsLDtsMSMNSsP
0 3
CBL (human) stFsLDtsMSMNSsP S646-p
CBL (mouse) sTFsLDTSMTMNSSP S644
CBL (rat) STFSLDTSTTMNSSP S645
S652-p
tsMSMNSsPLVGPEC
0 1
CBL (human) tsMSMNSsPLVGPEC S652-p
CBL (mouse) TSMTMNSSPVAGPES S650
CBL (rat) TSTTMNSSPVAGPES S651
S667-p
DHPKIKPsssANAIy
0 26
CBL (human) DHPKIKPsssANAIy S667-p
CBL (mouse) EHPKIKPSssANAIy S665
CBL (rat) EHPKIKPSSSANAIy S666
S668-p
HPKIKPsssANAIys
0 18
CBL (human) HPKIKPsssANAIys S668-p
CBL (mouse) HPKIKPSssANAIys S666-p
CBL (rat) HPKIKPSSSANAIyS S667
S669-p
PKIKPsssANAIysL
Upstream
0 228
Regulatory protein:
  • ZAP70 (human)
Treatment
  • SII_angiotensin_2
CBL (human) PKIKPsssANAIysL S669-p
CBL (mouse) PKIKPSssANAIysL S667-p
CBL (rat) PKIKPSSSANAIySL S668
Y674-p
sssANAIysLAARPL
Upstream
Downstream
2 739
Effects on Biological Processes:
  • cell motility, altered
Regulatory protein:
  • ZAP70 (human)
Treatment
  • EGF
  • erlotinib
  • gefitinib
  • PKC412
  • Su11274
CBL (human) sssANAIysLAARPL Y674-p
CBL (mouse) SssANAIysLAARPL Y672-p
CBL (rat) SSSANAIySLAARPL Y673-p
S675-p
ssANAIysLAARPLP
0 110
CBL (human) ssANAIysLAARPLP S675-p
CBL (mouse) ssANAIysLAARPLP S673-p
CBL (rat) SSANAIySLAARPLP S674
G694
PPGEQCEGEEDtEyM
0 11
CBL (human) PPGEQCEGEEDtEyM G694
CBL (mouse) PPGEQGEsEEDtEyM S692-p
CBL (rat) PPGEQGDsEEDTEyM S693-p
T698-p
QCEGEEDtEyMtPss
0 26
CBL (human) QCEGEEDtEyMtPss T698-p
CBL (mouse) QGEsEEDtEyMTPTs T696-p
CBL (rat) QGDsEEDTEyMTPTS T697
Y700-p
EGEEDtEyMtPssRP
Upstream
Downstream
14 509
CBL (human)
Y700-p
CBL (rat)
Y699-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • cell growth, altered
  • cell growth, induced
  • cell motility, altered
  • signaling pathway regulation
Putative in vivo kinases:
  • Abl (mouse)
  • Fyn (human)
  • INSR (rat)
  • Lck (human)
  • Syk (human)
Regulatory protein:
  • EGFR (human)
  • LYN (human)
Treatment
  • anti-CD3
  • dasatinib
  • EGF
  • erlotinib
  • fibrinogen
  • gefitinib
  • insulin
  • MG132
  • OXSI-2
  • PAR4-activating_peptide
  • PKC412
  • PP2
  • Su11274
  • vanadate
CBL (human) EGEEDtEyMtPssRP Y700-p
CBL (mouse) EsEEDtEyMTPTsRP Y698-p
CBL (rat) DsEEDTEyMTPTSRP Y699-p
T702-p
EEDtEyMtPssRPLR
0 13
CBL (human) EEDtEyMtPssRPLR T702-p
CBL (mouse) EEDtEyMTPTsRPVG T700
CBL (rat) EEDTEyMTPTSRPVG T701
S704-p
DtEyMtPssRPLRPL
0 34
CBL (human) DtEyMtPssRPLRPL S704-p
CBL (mouse) DtEyMTPTsRPVGVQ T702
CBL (rat) DTEyMTPTSRPVGVQ T703
S705-p
tEyMtPssRPLRPLD
0 23
CBL (human) tEyMtPssRPLRPLD S705-p
CBL (mouse) tEyMTPTsRPVGVQK S703-p
CBL (rat) TEyMTPTSRPVGVQK S704
T713-p
RPLRPLDtsQssRAC
0 1
CBL (human) RPLRPLDtsQssRAC T713-p
CBL (mouse) EPKRPLEATQsSRAC A719
CBL (rat) EPKRPAETAQSSRAC T720
S714-p
PLRPLDtsQssRACD
0 4
CBL (human) PLRPLDtsQssRACD S714-p
CBL (mouse) PKRPLEATQsSRACD T720
CBL (rat) PKRPAETAQSSRACD A721
S716-p
RPLDtsQssRACDCD
0 5
CBL (human) RPLDtsQssRACDCD S716-p
CBL (mouse) RPLEATQsSRACDCD S722-p
CBL (rat) RPAETAQSSRACDCD S723
S717-p
PLDtsQssRACDCDQ
0 4
CBL (human) PLDtsQssRACDCDQ S717-p
CBL (mouse) PLEATQsSRACDCDQ S723
CBL (rat) PAETAQSSRACDCDQ S724
Y731-p
QQIDSCTyEAMyNIQ
Upstream
Downstream
16 35
CBL (human)
Y731-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
Effects on Biological Processes:
  • cell growth, altered
  • cell growth, induced
  • cell motility, altered
  • signaling pathway regulation
Kinase, in vitro:
  • Fyn (human)
Putative in vivo kinases:
  • Fyn (human)
  • Lck (human)
  • Src (human)
  • Syk (human)
Regulatory protein:
  • PTPRJ (human)
Treatment
  • anti-CD3
  • EGF
  • fibrinogen
  • OXSI-2
  • PAR4-activating_peptide
  • PP1
  • PP2
  • vanadate
CBL (human) QQIDSCTyEAMyNIQ Y731-p
CBL (mouse) QQIDSCTyEAMYNIQ Y737-p
CBL (rat) QQIDSCTYEAMYNIQ Y738
Y735-p
SCTyEAMyNIQSQAP
0 4
CBL (human) SCTyEAMyNIQSQAP Y735-p
CBL (mouse) SCTyEAMYNIQSQAL Y741
CBL (rat) SCTYEAMYNIQSQAL Y742
T762-p
LAAAHANtGPEEsEN
0 3
CBL (human) LAAAHANtGPEEsEN T762-p
CBL (mouse) LATAHTSTGPEEsEN T768
CBL (rat) LATAHTSTGPEESEN T769
S767-p
ANtGPEEsENEDDGy
0 252
CBL (human) ANtGPEEsENEDDGy S767-p
CBL (mouse) TSTGPEEsENEDDGy S773-p
CBL (rat) TSTGPEESENEDDGY S774
Y774-p
sENEDDGyDVPKPPV
Upstream
Downstream
15 260
CBL (human)
Y774-p
CBL (mouse)
Y780-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • cell adhesion, induced
  • cell growth, altered
  • cell growth, induced
  • cell motility, altered
  • cell motility, induced
  • signaling pathway regulation
Putative in vivo kinases:
  • Abl (mouse)
  • Fyn (human)
  • INSR (rat)
  • Lck (human)
  • Src (human)
  • Syk (human)
Regulatory protein:
  • LYN (human)
Treatment
  • anti-CD3
  • dasatinib
  • EGF
  • fibrinogen
  • insulin
  • M-CSF
  • OXSI-2
  • PAR4-activating_peptide
  • PKC412
  • PP2
  • vanadate
CBL (human) sENEDDGyDVPKPPV Y774-p
CBL (mouse) sENEDDGyDVPKPPV Y780-p
CBL (rat) SENEDDGYDVPKPPV Y781
T789-p
PAVLARRtLsDIsNA
0 8
CBL (human) PAVLARRtLsDIsNA T789-p
CBL (mouse) PAVLARRtLsDISNA T795-p
CBL (rat) PAVLARRTLSDISNA T796
S791-p
VLARRtLsDIsNAsS
0 45
CBL (human) VLARRtLsDIsNAsS S791-p
CBL (mouse) VLARRtLsDISNAss S797-p
CBL (rat) VLARRTLSDISNASS S798
S794-p
RRtLsDIsNAsSsFG
0 1
CBL (human) RRtLsDIsNAsSsFG S794-p
CBL (mouse) RRtLsDISNAsssFG S800
CBL (rat) RRTLSDISNASSSFG S801
S797-p
LsDIsNAsSsFGWLs
0 2
CBL (human) LsDIsNAsSsFGWLs S797-p
CBL (mouse) LsDISNAsssFGWLs S803-p
CBL (rat) LSDISNASSSFGWLS S804
S798
sDIsNAsSsFGWLsL
0 1
CBL (human) sDIsNAsSsFGWLsL S798
CBL (mouse) sDISNAsssFGWLsL S804-p
CBL (rat) SDISNASSSFGWLSL S805
S799-p
DIsNAsSsFGWLsLD
0 5
CBL (human) DIsNAsSsFGWLsLD S799-p
CBL (mouse) DISNAsssFGWLsLD S805-p
CBL (rat) DISNASSSFGWLSLD S806
S804-p
sSsFGWLsLDGDPTT
0 15
CBL (human) sSsFGWLsLDGDPTT S804-p
CBL (mouse) sssFGWLsLDGDPTN S810-p
CBL (rat) SSSFGWLSLDGEPTN S811
S833-p
PFPRRINsERKAGSC
0 12
CBL (human) PFPRRINsERKAGSC S833-p
CBL (mouse) PFPRRINSERKASSy S838
CBL (rat) PFPRRINSERKASSY S839
C840
sERKAGSCQQGSGPA
0 30
CBL (human) sERKAGSCQQGSGPA C840
CBL (mouse) SERKASSyQQGGGAT Y845-p
CBL (rat) SERKASSYQQGGGAM Y846
S866-p
SEIENLMsQGYSYQD
Upstream
Downstream
1 1
Effects on Modified Protein
  • neddylation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • cell growth, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • adriamycin
  • KU-55933
  • MMS
CBL (human) SEIENLMsQGYSYQD S866-p
CBL (mouse) SEIERLMSQGYSYQD S873
CBL (rat) SEIERLMSQGYSYQD S874
S897
NILREFVSISsPAHV
0 1
CBL (human) NILREFVSISsPAHV S897
CBL (mouse) NILREFVsISSPAHV S904-p
CBL (rat) NILREFVSISSPAHV S905
S900-p
REFVSISsPAHVAT_
0 4
CBL (human) REFVSISsPAHVAT_ S900-p
CBL (mouse) REFVsISSPAHVAT_ S907
CBL (rat) REFVSISSPAHVAT_ S908