Other Species / Isoforms
  SNCA (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K6-ac
__MDVFMkGLSkAkE
Upstream
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • autophagy, induced
  • cytoskeletal reorganization
Treatment
  • development
  • siRNA
SNCA (human) __MDVFMKGLSkAkE K6
SNCA (mouse) __MDVFMkGLSkAkE K6-ac
SNCA (rat) __MDVFMkGLSKAKE K6-ac
K6-ub
__MDVFMkGLSkAkE
0 2
SNCA (human) __MDVFMkGLSkAkE K6-ub
SNCA (mouse) __MDVFMkGLSkAkE K6-ub
SNCA (rat) __MDVFMKGLSKAKE K6
K6
__MDVFMKGLSkAkE
1 1
SNCA (human) __MDVFMkGLSkAkE K6-sm
SNCA (mouse) __MDVFMKGLSkAkE K6
SNCA (rat) __MDVFMKGLSKAKE K6
K10-ac
VFMkGLSkAkEGVVA
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • autophagy, induced
  • cytoskeletal reorganization
Treatment
  • development
  • siRNA
SNCA (human) VFMkGLSKAkEGVVA K10
SNCA (mouse) VFMkGLSkAkEGVVA K10-ac
SNCA (rat) VFMkGLSKAKEGVVA K10
K10
VFMkGLSKAkEGVVA
1 1
SNCA (human) VFMkGLSkAkEGVVA K10-sm
SNCA (mouse) VFMkGLSKAkEGVVA K10
SNCA (rat) VFMkGLSKAKEGVVA K10
K12-m1
MkGLSkAkEGVVAAA
0 1
SNCA (human) MkGLSkAKEGVVAAA K12
SNCA (mouse) MkGLSkAkEGVVAAA K12-m1
SNCA (rat) MkGLSKAKEGVVAAA K12
K12
MkGLSkAKEGVVAAA
1 2
SNCA (human) MkGLSkAkEGVVAAA K12-ub
SNCA (mouse) MkGLSkAKEGVVAAA K12
SNCA (rat) MkGLSKAKEGVVAAA K12
K12
MkGLSkAKEGVVAAA
1 1
SNCA (human) MkGLSkAkEGVVAAA K12-sm
SNCA (mouse) MkGLSkAKEGVVAAA K12
SNCA (rat) MkGLSKAKEGVVAAA K12
K21
GVVAAAEKTKQGVAE
0 2
SNCA (human) GVVAAAEkTkQGVAE K21-ac
SNCA (mouse) GVVAAAEKTKQGVAE K21
SNCA (rat) GVVAAAEKTKQGVAE K21
K21
GVVAAAEKTKQGVAE
1 1
SNCA (human) GVVAAAEkTkQGVAE K21-ub
SNCA (mouse) GVVAAAEKTKQGVAE K21
SNCA (rat) GVVAAAEKTKQGVAE K21
K21
GVVAAAEKTKQGVAE
1 1
SNCA (human) GVVAAAEkTkQGVAE K21-sm
SNCA (mouse) GVVAAAEKTKQGVAE K21
SNCA (rat) GVVAAAEKTKQGVAE K21
K23
VAAAEKTKQGVAEAA
0 1
SNCA (human) VAAAEkTkQGVAEAA K23-ac
SNCA (mouse) VAAAEKTKQGVAEAA K23
SNCA (rat) VAAAEKTKQGVAEAA K23
K23
VAAAEKTKQGVAEAA
1 5
SNCA (human) VAAAEkTkQGVAEAA K23-ub
SNCA (mouse) VAAAEKTKQGVAEAA K23
SNCA (rat) VAAAEKTKQGVAEAA K23
K23
VAAAEKTKQGVAEAA
1 1
SNCA (human) VAAAEkTkQGVAEAA K23-sm
SNCA (mouse) VAAAEKTKQGVAEAA K23
SNCA (rat) VAAAEKTKQGVAEAA K23
K32
GVAEAAGKTKEGVLy
0 1
SNCA (human) GVAEAAGkTkEGVLy K32-ac
SNCA (mouse) GVAEAAGKTKEGVLy K32
SNCA (rat) GVAEAAGKTkEGVLy K32
K34
AEAAGKTKEGVLyVG
0 2
SNCA (human) AEAAGkTkEGVLyVG K34-ac
SNCA (mouse) AEAAGKTKEGVLyVG K34
SNCA (rat) AEAAGKTkEGVLyVG K34-ac
K34
AEAAGKTKEGVLyVG
1 1
SNCA (human) AEAAGkTkEGVLyVG K34-sm
SNCA (mouse) AEAAGKTKEGVLyVG K34
SNCA (rat) AEAAGKTKEGVLyVG K34
Y39-p
KTKEGVLyVGsKTkE
Upstream
9 15
Treatment
  • IkT-148009
  • MPTP
SNCA (human) kTkEGVLyVGsKTkE Y39-p
SNCA (mouse) KTKEGVLyVGsKTkE Y39-p
SNCA (rat) KTkEGVLyVGskTkE Y39-p
S42-p
EGVLyVGsKTkEGVV
0 6
SNCA (human) EGVLyVGsKTkEGVV S42-p
SNCA (mouse) EGVLyVGsKTkEGVV S42-p
SNCA (rat) EGVLyVGskTkEGVV S42-p
K43
GVLyVGsKTkEGVVH
0 2
SNCA (human) GVLyVGsKTkEGVVH K43
SNCA (mouse) GVLyVGsKTkEGVVH K43
SNCA (rat) GVLyVGskTkEGVVH K43-ub
K45
LyVGsKTKEGVVHGV
0 2
SNCA (human) LyVGsKTkEGVVHGV K45-ac
SNCA (mouse) LyVGsKTKEGVVHGV K45
SNCA (rat) LyVGskTkEGVVHGV K45-ac
K45-m1
LyVGsKTkEGVVHGV
0 1
SNCA (human) LyVGsKTKEGVVHGV K45
SNCA (mouse) LyVGsKTkEGVVHGV K45-m1
SNCA (rat) LyVGskTKEGVVHGV K45
K45
LyVGsKTKEGVVHGV
1 1
SNCA (human) LyVGsKTkEGVVHGV K45-ub
SNCA (mouse) LyVGsKTKEGVVHGV K45
SNCA (rat) LyVGskTKEGVVHGV K45
K45
LyVGsKTKEGVVHGV
1 1
SNCA (human) LyVGsKTkEGVVHGV K45-sm
SNCA (mouse) LyVGsKTKEGVVHGV K45
SNCA (rat) LyVGskTKEGVVHGV K45
T53-gl
EGVVHGVttVAEKtK
0 1
SNCA (human) EGVVHGVAtVAEktk A53
SNCA (mouse) EGVVHGVttVAEKtK T53-gl
SNCA (rat) EGVVHGVTTVAEKTK T53
T54-gl
GVVHGVttVAEKtKE
0 1
SNCA (human) GVVHGVATVAEktkE T54
SNCA (mouse) GVVHGVttVAEKtKE T54-gl
SNCA (rat) GVVHGVTTVAEKTKE T54
T54
GVVHGVtTVAEKtKE
0 1
SNCA (human) GVVHGVAtVAEktkE T54-ga
SNCA (mouse) GVVHGVtTVAEKtKE T54
SNCA (rat) GVVHGVTTVAEKTKE T54
K58
GVttVAEKtKEQVtN
0 2
SNCA (human) GVAtVAEktkEQVtN K58-ac
SNCA (mouse) GVttVAEKtKEQVtN K58
SNCA (rat) GVTTVAEKTKEQVTN K58
K58
GVttVAEKtKEQVtN
1 1
SNCA (human) GVAtVAEktkEQVtN K58-ub
SNCA (mouse) GVttVAEKtKEQVtN K58
SNCA (rat) GVTTVAEKTKEQVTN K58
T59
VttVAEKTKEQVtNV
0 1
SNCA (human) VAtVAEktkEQVtNV T59-p
SNCA (mouse) VttVAEKTKEQVtNV T59
SNCA (rat) VTTVAEKTKEQVTNV T59
T59-gl
VttVAEKtKEQVtNV
0 1
SNCA (human) VAtVAEkTkEQVtNV T59
SNCA (mouse) VttVAEKtKEQVtNV T59-gl
SNCA (rat) VTTVAEKTKEQVTNV T59
K60
ttVAEKtKEQVtNVG
0 1
SNCA (human) AtVAEktkEQVtNVG K60-ac
SNCA (mouse) ttVAEKtKEQVtNVG K60
SNCA (rat) TTVAEKTKEQVTNVG K60
K60
ttVAEKtKEQVtNVG
1 2
SNCA (human) AtVAEktkEQVtNVG K60-ub
SNCA (mouse) ttVAEKtKEQVtNVG K60
SNCA (rat) TTVAEKTKEQVTNVG K60
K60
ttVAEKtKEQVtNVG
1 1
SNCA (human) AtVAEktkEQVtNVG K60-sm
SNCA (mouse) ttVAEKtKEQVtNVG K60
SNCA (rat) TTVAEKTKEQVTNVG K60
T64-p
EKtKEQVtNVGGAVV
Upstream
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
  • CK1D (human)
  • CK1E (human)
  • CK1G1 (human)
  • CK1G2 (human)
  • CK1G3 (human)
Treatment
  • development
SNCA (human) EktkEQVtNVGGAVV T64-p
SNCA (mouse) EKtKEQVtNVGGAVV T64-p
SNCA (rat) EKTKEQVTNVGGAVV T64
T64-gl
EKtKEQVtNVGGAVV
0 1
SNCA (human) EktkEQVTNVGGAVV T64
SNCA (mouse) EKtKEQVtNVGGAVV T64-gl
SNCA (rat) EKTKEQVTNVGGAVV T64
T72
NVGGAVVTGVTAVAQ
0 1
SNCA (human) NVGGAVVtGVTAVAQ T72-p
SNCA (mouse) NVGGAVVTGVTAVAQ T72
SNCA (rat) NVGGAVVTGVTAVAQ T72
T72-gl
NVGGAVVtGVTAVAQ
1 4
SNCA (human) NVGGAVVtGVTAVAQ T72-gl
SNCA (mouse) NVGGAVVtGVTAVAQ T72-gl
SNCA (rat) NVGGAVVtGVTAVAQ T72-gl
K80
GVTAVAQKTVEGAGN
0 1
SNCA (human) GVTAVAQktVEGAGs K80-ac
SNCA (mouse) GVTAVAQKTVEGAGN K80
SNCA (rat) GVTAVAQKTVEGAGN K80
K80
GVTAVAQKTVEGAGN
0 1
SNCA (human) GVTAVAQktVEGAGs K80-ub
SNCA (mouse) GVTAVAQKTVEGAGN K80
SNCA (rat) GVTAVAQKTVEGAGN K80
K80
GVTAVAQKTVEGAGN
1 1
SNCA (human) GVTAVAQktVEGAGs K80-sm
SNCA (mouse) GVTAVAQKTVEGAGN K80
SNCA (rat) GVTAVAQKTVEGAGN K80
T81
VTAVAQKTVEGAGNI
0 1
SNCA (human) VTAVAQktVEGAGsI T81-p
SNCA (mouse) VTAVAQKTVEGAGNI T81
SNCA (rat) VTAVAQKTVEGAGNI T81
T81
VTAVAQKTVEGAGNI
0 1
SNCA (human) VTAVAQktVEGAGsI T81-gl
SNCA (mouse) VTAVAQKTVEGAGNI T81
SNCA (rat) VTAVAQKTVEGAGNI T81
N87
KTVEGAGNIAAATGF
9 1
SNCA (human) ktVEGAGsIAAATGF S87-p
SNCA (mouse) KTVEGAGNIAAATGF N87
SNCA (rat) KTVEGAGNIAAATGF N87
N87
KTVEGAGNIAAATGF
0 2
SNCA (human) ktVEGAGsIAAATGF S87-gl
SNCA (mouse) KTVEGAGNIAAATGF N87
SNCA (rat) KTVEGAGNIAAATGF N87
K96
AAATGFVKKDQMGkG
0 2
SNCA (human) AAATGFVkKDQLGkN K96-ac
SNCA (mouse) AAATGFVKKDQMGkG K96
SNCA (rat) AAATGFVKKDQMGKG K96
K96-ub
AAATGFVkKDQMGkG
0 1
SNCA (human) AAATGFVKKDQLGkN K96
SNCA (mouse) AAATGFVkKDQMGkG K96-ub
SNCA (rat) AAATGFVKKDQMGKG K96
K96-sm
AAATGFVkKDQMGkG
5 1
SNCA (human) AAATGFVkKDQLGkN K96-sm
SNCA (mouse) AAATGFVkKDQMGkG K96-sm
SNCA (rat) AAATGFVKKDQMGKG K96
K102-sm
VkKDQMGkGEEGYPQ
5 1
SNCA (human) VkKDQLGkNEEGAPQ K102-sm
SNCA (mouse) VkKDQMGkGEEGYPQ K102-sm
SNCA (rat) VKKDQMGKGEEGYPQ K102
Y125-p
VDPGSEAyEMPsEEG
9 1
SNCA (human) VDPDNEAyEMPsEEG Y125-p
SNCA (mouse) VDPGSEAyEMPsEEG Y125-p
SNCA (rat) VDPSSEAYEMPsEEG Y125
S129-p
SEAyEMPsEEGYQDY
Upstream
Downstream
145 7
SNCA (human)
S129-p
SNCA (mouse)
S129-p
SNCA (rat)
S129-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
  • receptor internalization, induced
Effects on Biological Processes:
  • endocytosis, induced
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • PLK2 (human)
  • PLK3 (human)
  • PLK3 (mouse)
Putative in vivo kinases:
  • CK2A1 (mouse)
  • PLK2 (mouse)
  • PLK2 (rat)
Putative upstream phosphatases:
  • PPP2CA (human)
  • PPP2CA (rat)
Regulatory protein:
  • APOE (human)
  • Bcl-11A (mouse)
  • DNAJC6 (human)
  • DYRK1A (human)
  • FABP3 (human)
  • GBA (human)
  • SLC18A2 (human)
  • SNCA (mouse)
Treatment
  • aggregation
  • APV
  • bacterial infection
  • BI2536
  • bicuculline
  • C2-ceramide
  • calyculin_A
  • CNQX
  • cold_water_stress
  • complement receptor 3
  • compound 37
  • development
  • enriched environment
  • Fiber deprived diet
  • FK506
  • hypoxia
  • iHAP1
  • IkT-148009
  • Irisin
  • LB-100
  • LY341495
  • LY354740
  • minocycline
  • MPTP
  • NH4Cl
  • NXP031
  • peptide
  • peptide inhibitor
  • picrotoxin
  • PLX3397
  • pravastatin
  • preformed fibrils
  • rotenone
  • simvastatin
  • SKI-606
  • sleep
  • sleep deprivation
  • streptozotocin
  • TTX
  • withaferin_A
SNCA (human) NEAyEMPsEEGyQDy S129-p
SNCA (mouse) SEAyEMPsEEGYQDY S129-p
SNCA (rat) SEAYEMPsEEGYQDY S129-p
Y133
EMPsEEGYQDYEPEA
3 0
SNCA (human) EMPsEEGyQDyEPEA Y133-p
SNCA (mouse) EMPsEEGYQDYEPEA Y133
SNCA (rat) EMPsEEGYQDYEPEA Y133
Y136
sEEGYQDYEPEA___
2 0
SNCA (human) sEEGyQDyEPEA___ Y136-p
SNCA (mouse) sEEGYQDYEPEA___ Y136
SNCA (rat) sEEGYQDYEPEA___ Y136