Other Species / Isoforms
  ATM (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T39-p
RLIRDPEtIkHLDRH
0 1
ATM (human) RLIRDPEtIkHLDRH T39-p
ATM (mouse) RLIQDPETVQHLDRH T39
ATM (rat) RLIQDPETVQHLDRH T39
K41-ub
IRDPEtIkHLDRHsD
0 2
ATM (human) IRDPEtIkHLDRHsD K41-ub
ATM (mouse) IQDPETVQHLDRHSD Q41
ATM (rat) IQDPETVQHLDRHSD Q41
S47-p
IkHLDRHsDsKQGky
0 1
ATM (human) IkHLDRHsDsKQGky S47-p
ATM (mouse) VQHLDRHSDSKQGKY S47
ATM (rat) VQHLDRHSDSKQGKY S47
S49-p
HLDRHsDsKQGkyLN
0 1
ATM (human) HLDRHsDsKQGkyLN S49-p
ATM (mouse) HLDRHSDSKQGKYLN S49
ATM (rat) HLDRHSDSKQGKYLN S49
K53-ub
HsDsKQGkyLNWDAV
0 1
ATM (human) HsDsKQGkyLNWDAV K53-ub
ATM (mouse) HSDSKQGKYLNWDAV K53
ATM (rat) HSDSKQGKYLNWDAV K53
Y54-p
sDsKQGkyLNWDAVF
0 1
ATM (human) sDsKQGkyLNWDAVF Y54-p
ATM (mouse) SDSKQGKYLNWDAVF Y54
ATM (rat) SDSKQGKYLNWDAVF Y54
K66-ub
AVFRFLQkYIQkEtE
0 1
ATM (human) AVFRFLQkYIQkEtE K66-ub
ATM (mouse) AVFRFLQKYIQKEME K66
ATM (rat) AVFRFLQKYIQKETE K66
K70-ub
FLQkYIQkEtECLRI
0 2
ATM (human) FLQkYIQkEtECLRI K70-ub
ATM (mouse) FLQKYIQKEMESLRT K70
ATM (rat) FLQKYIQKETESLRT K70
T72-p
QkYIQkEtECLRIAk
0 1
ATM (human) QkYIQkEtECLRIAk T72-p
ATM (mouse) QKYIQKEMESLRTAK M72
ATM (rat) QKYIQKETESLRTAK T72
K79-ub
tECLRIAkPNVsAst
0 3
ATM (human) tECLRIAkPNVsAst K79-ub
ATM (mouse) MESLRTAKSNVSATT K79
ATM (rat) TESLRTAKSNVSAST K79
S83-p
RIAkPNVsAstQASR
0 1
ATM (human) RIAkPNVsAstQASR S83-p
ATM (mouse) RTAKSNVSATTQSSR S83
ATM (rat) RTAKSNVSASTQTSR S83
S85-p
AkPNVsAstQASRQK
Upstream
Downstream
1 4
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
Treatment
  • ionizing_radiation
ATM (human) AkPNVsAstQASRQK S85-p
ATM (mouse) AKSNVSATTQSSRQK T85
ATM (rat) AKSNVSASTQTSRQK S85
T86-p
kPNVsAstQASRQKK
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
Treatment
  • bleomycin
ATM (human) kPNVsAstQASRQKK T86-p
ATM (mouse) KSNVSATTQSSRQKK T86
ATM (rat) KSNVSASTQTSRQKK T86
K106-ub
SLVKYFIkCANRRAP
0 1
ATM (human) SLVKYFIkCANRRAP K106-ub
ATM (mouse) SLVRYFIKCANKRAP K106
ATM (rat) SLVRFFIKCANKRAP K106
K116-ub
NRRAPRLkCQELLNY
0 1
ATM (human) NRRAPRLkCQELLNY K116-ub
ATM (mouse) NKRAPRLKCQDLLNY K116
ATM (rat) NKRAPRLKCQDLLNY K116
K147-ub
DCSNILLkDILSVRK
0 1
ATM (human) DCSNILLkDILSVRK K147-ub
ATM (mouse) DCSNILLKDILSVRK K147
ATM (rat) DCSNILLKDILSVRK K147
K177-ub
VYFRLYLkPSQDVHR
0 1
ATM (human) VYFRLYLkPSQDVHR K177-ub
ATM (mouse) LYFRLYLKPSQDINR K177
ATM (rat) LYIRLYLKPSQDINR K177
K196-ub
RIIHAVTkGCCsQtD
0 2
ATM (human) RIIHAVTkGCCsQtD K196-ub
ATM (mouse) RIIHAVTRGCCSQTD R196
ATM (rat) RIIHAVTRGCCSQTD R196
S200-p
AVTkGCCsQtDGLNS
0 1
ATM (human) AVTkGCCsQtDGLNS S200-p
ATM (mouse) AVTRGCCSQTDGLPS S200
ATM (rat) AVTRGCCSQTDGLPS S200
T202-p
TkGCCsQtDGLNSkF
0 1
ATM (human) TkGCCsQtDGLNSkF T202-p
ATM (mouse) TRGCCSQTDGLPSKF T202
ATM (rat) TRGCCSQTDGLPSKF T202
K208-ub
QtDGLNSkFLDFFsk
0 1
ATM (human) QtDGLNSkFLDFFsk K208-ub
ATM (mouse) QTDGLPSKFLDLFSK K208
ATM (rat) QTDGLPSKFLDLFSK K208
S214-p
SkFLDFFskAIQCAR
0 1
ATM (human) SkFLDFFskAIQCAR S214-p
ATM (mouse) SKFLDLFSKAIQYAR S214
ATM (rat) SKFLDLFSKAIQYAR S214
K215-ub
kFLDFFskAIQCARQ
0 1
ATM (human) kFLDFFskAIQCARQ K215-ub
ATM (mouse) KFLDLFSKAIQYARQ K215
ATM (rat) KFLDLFSKAIQYARQ K215
T237-p
NHILAALtIFLKTLA
0 4
ATM (human) NHILAALtIFLKTLA T237-p
ATM (mouse) SHILAALNIFLKSLA N237
ATM (rat) SHILAALNIFLKTLA N237
T297-p
HHPKGAKtQEKGAyE
0 1
ATM (human) HHPKGAKtQEKGAyE T297-p
ATM (mouse) HHPQGARAPEEGAYE A297
ATM (rat) HHPQGAKAPEEGAYE A297
Y303-p
KtQEKGAyEsTkWRs
0 1
ATM (human) KtQEKGAyEsTkWRs Y303-p
ATM (mouse) RAPEEGAYESMKWKS Y303
ATM (rat) KAPEEGAYESMKWKR Y303
S305-p
QEKGAyEsTkWRsIL
0 1
ATM (human) QEKGAyEsTkWRsIL S305-p
ATM (mouse) PEEGAYESMKWKSIL S305
ATM (rat) PEEGAYESMKWKRIL S305
K307-ub
KGAyEsTkWRsILyN
0 1
ATM (human) KGAyEsTkWRsILyN K307-ub
ATM (mouse) EGAYESMKWKSILYN K307
ATM (rat) EGAYESMKWKRILYN K307
S310-p
yEsTkWRsILyNLYD
0 1
ATM (human) yEsTkWRsILyNLYD S310-p
ATM (mouse) YESMKWKSILYNLYD S310
ATM (rat) YESMKWKRILYNLYD R310
Y313-p
TkWRsILyNLYDLLV
0 1
ATM (human) TkWRsILyNLYDLLV Y313-p
ATM (mouse) MKWKSILYNLYDLLV Y313
ATM (rat) MKWKRILYNLYDLLV Y313
K331-ub
SHIGSRGkySSGFRN
0 1
ATM (human) SHIGSRGkySSGFRN K331-ub
ATM (mouse) SHIGSRGKYSSGSRN K331
ATM (rat) SHIGSRGKYSSGSRN K331
Y332-p
HIGSRGkySSGFRNI
0 1
ATM (human) HIGSRGkySSGFRNI Y332-p
ATM (mouse) HIGSRGKYSSGSRNI Y332
ATM (rat) HIGSRGKYSSGSRNI Y332
S367-p
DTRSLEIsQSyTttQ
Upstream
Downstream
3 11
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
  • KU-55933
  • UV
  • wortmannin
ATM (human) DTRSLEIsQSyTttQ S367-p
ATM (mouse) DTRSVEIsQSYVTQR S367-p
ATM (rat) DTRSVEISQSYATQR S367
Y370-p
SLEIsQSyTttQRES
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • EGFR (human)
Putative in vivo kinases:
  • EGFR (human)
Treatment
  • ionizing_radiation
ATM (human) SLEIsQSyTttQRES Y370-p
ATM (mouse) SVEIsQSYVTQREST Y370
ATM (rat) SVEISQSYATQREST Y370
T372-p
EIsQSyTttQRESSD
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
ATM (human) EIsQSyTttQRESSD T372-p
ATM (mouse) EIsQSYVTQRESTDY T372
ATM (rat) EISQSYATQRESTDY T372
T373-p
IsQSyTttQRESSDy
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
ATM (human) IsQSyTttQRESSDy T373-p
ATM (mouse) gap -
ATM (rat) gap -
Y380-p
tQRESSDysVPCkRK
0 2
ATM (human) tQRESSDysVPCkRK Y380-p
ATM (mouse) TQRESTDYSVPCKRR Y379
ATM (rat) TQRESTDYSVPCKRR Y379
S381-p
QRESSDysVPCkRKK
0 1
ATM (human) QRESSDysVPCkRKK S381-p
ATM (mouse) QRESTDYSVPCKRRK S380
ATM (rat) QRESTDYSVPCKRRK S380
K385-ub
SDysVPCkRKKIELG
0 2
ATM (human) SDysVPCkRKKIELG K385-ub
ATM (mouse) TDYSVPCKRRKIDVG K384
ATM (rat) TDYSVPCKRRKIDIG K384
K397-ub
ELGWEVIkDHLQKSQ
0 1
ATM (human) ELGWEVIkDHLQKSQ K397-ub
ATM (mouse) DVGWEVIKDYLQKSQ K396
ATM (rat) DIGWEVIKDYLQKSQ K396
S440-p
SPLLMILsQLLPQQR
Upstream
1 0
Kinase, in vitro:
  • ATM (human)
ATM (human) SPLLMILsQLLPQQR S440-p
ATM (mouse) SPLILILYQLLPQQR Y439
ATM (rat) SPLILILYQLLPQQR Y439
K468-ub
EVALCQDkRSNLESS
0 1
ATM (human) EVALCQDkRSNLESS K468-ub
ATM (mouse) EVALCQGKKSNLESS K467
ATM (rat) EVALCQGKKSNLESS K467
K477-ub
SNLESSQkSDLLKLW
0 2
ATM (human) SNLESSQkSDLLKLW K477-ub
ATM (mouse) SNLESSQKSDLLKLW K476
ATM (rat) SNLESSQKSDLLKLW K476
K573-ub
VNRSFSLkESIMKWL
0 2
ATM (human) VNRSFSLkESIMKWL K573-ub
ATM (mouse) ANRSFSVKESIMRWL K572
ATM (rat) ANRSFSVKESIMRWL K572
S644-p
QKDKEELsFsEVEEL
0 1
ATM (human) QKDKEELsFsEVEEL S644-p
ATM (mouse) CEDKEEPSFSEVEEL S643
ATM (rat) CEDTEEPSFSEAEEL S643
S646-p
DKEELsFsEVEELFL
0 1
ATM (human) DKEELsFsEVEELFL S646-p
ATM (mouse) DKEEPSFSEVEELFL S645
ATM (rat) DTEEPSFSEAEELFL S645
K673-ub
VRECGIEkHQSSIGF
0 1
ATM (human) VRECGIEkHQSSIGF K673-ub
ATM (mouse) VKEYAVEKFQSSVGF K672
ATM (rat) VKEDTVEKFQSRVGF K672
K748-ub
YKSELFQkAkSLMQC
0 1
ATM (human) YKSELFQkAkSLMQC K748-ub
ATM (mouse) HKSELFQKAKSLMQC K747
ATM (rat) YKSELFQKAKSLMQC K747
K750-ub
SELFQkAkSLMQCAG
0 1
ATM (human) SELFQkAkSLMQCAG K750-ub
ATM (mouse) SELFQKAKSLMQCAG K749
ATM (rat) SELFQKAKSLMQCAG K749
K764-ub
GESITLFkNKTNEEF
0 1
ATM (human) GESITLFkNKTNEEF K764-ub
ATM (mouse) GESISLFKNKTNEES K763
ATM (rat) GESISLFKNKTNEES K763
S794-p
LSNCTKKsPNKIASG
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • camptothecin
  • seliciclib
  • siRNA
ATM (human) LSNCTKKsPNKIASG S794-p
ATM (mouse) LCIHTKHTPNKIASG T793
ATM (rat) LCRHTKHTLNkIASG T793
K797
CTKKsPNKIASGFFL
0 1
ATM (human) CTKKsPNKIASGFFL K797
ATM (mouse) HTKHTPNKIASGFFL K796
ATM (rat) HTKHTLNkIASGFFL K796-ac
K810-ub
FLRLLTSkLMNDIAD
0 1
ATM (human) FLRLLTSkLMNDIAD K810-ub
ATM (mouse) FLRLLTSKLMNDIAD K809
ATM (rat) FLRLLTSKLMNDIAD K809
K820-ub
NDIADICksLASFIK
0 1
ATM (human) NDIADICksLASFIK K820-ub
ATM (mouse) NDIADICKSLASCTK K819
ATM (rat) NDIADICKSLASCTK K819
S821-p
DIADICksLASFIKK
0 1
ATM (human) DIADICksLASFIKK S821-p
ATM (mouse) DIADICKSLASCTKK S820
ATM (rat) DIADICKSLASCTKK S820
K926-ub
RAADIRRkLLMLIDS
0 1
ATM (human) RAADIRRkLLMLIDS K926-ub
ATM (mouse) RGADIRRKLLLLLDS K928
ATM (rat) RGADIRRKLLMLLDP K933
T935-p
LMLIDSStLEPTKSL
0 1
ATM (human) LMLIDSStLEPTKSL T935-p
ATM (mouse) LLLLDSSILDLMKPL I937
ATM (rat) LMLLDPSTLDLTKSL T942
Y980-p
LSNVCSLyRRDQDVC
0 1
ATM (human) LSNVCSLyRRDQDVC Y980-p
ATM (mouse) LSLVCSLHRRDQDVC H982
ATM (rat) LSLVCSLYRRDQDVC Y987
K988-ub
RRDQDVCkTILNHVL
0 1
ATM (human) RRDQDVCkTILNHVL K988-ub
ATM (mouse) RRDQDVCKTILSNVL K990
ATM (rat) RRDQDVCKTILSNVL K995
K1057-ub
LEADPYSkWAILNVM
0 1
ATM (human) LEADPYSkWAILNVM K1057-ub
ATM (mouse) LEADPYSEWAILNVK E1059
ATM (rat) LEADPYSKWAILNVK K1064
K1101-ub
NRLFQDTkGDSSRLL
0 2
ATM (human) NRLFQDTkGDSSRLL K1101-ub
ATM (mouse) NRLFQDMRQGDFSRS R1103
ATM (rat) SRLFQDMRQGDSSRS R1108
K1109-ub
GDSSRLLkALPLkLQ
Upstream
0 3
Treatment
  • MG132
ATM (human) GDSSRLLkALPLkLQ K1109-ub
ATM (mouse) GDFSRSLKALPLKFQ K1112
ATM (rat) GDSSRSLKALPLKFQ K1117
K1114-ub
LLkALPLkLQQTAFE
Upstream
0 4
Treatment
  • MG132
ATM (human) LLkALPLkLQQTAFE K1114-ub
ATM (mouse) SLKALPLKFQQTSFN K1117
ATM (rat) SLKALPLKFQQTSFN K1122
K1126-m1
AFENAYLkAQEGMRE
0 1
ATM (human) AFENAYLkAQEGMRE K1126-m1
ATM (mouse) SFNNAYTTAEAGIRG T1129
ATM (rat) SFNSAYMIAEAGIRE I1134
K1126-ub
AFENAYLkAQEGMRE
0 2
ATM (human) AFENAYLkAQEGMRE K1126-ub
ATM (mouse) SFNNAYTTAEAGIRG T1129
ATM (rat) SFNSAYMIAEAGIRE I1134
K1181-ub
FALCKSVkENGLEPH
0 1
ATM (human) FALCKSVkENGLEPH K1181-ub
ATM (mouse) FALCKSVKENRLEPH K1184
ATM (rat) FALCKSVKENGLEPH K1189
K1196-ub
LVKKVLEkVSETFGY
0 1
ATM (human) LVKKVLEkVSETFGY K1196-ub
ATM (mouse) LVKKVLEKVSESFGC K1199
ATM (rat) LVKKVLEKVSESFGC K1204
K1269-ub
RSHFDEVksIANQIQ
0 1
ATM (human) RSHFDEVksIANQIQ K1269-ub
ATM (mouse) RSHFDEVKSIANQIQ K1272
ATM (rat) RKHFDEVKSIANQIQ K1277
S1270-p
SHFDEVksIANQIQE
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell growth, induced
  • transcription, altered
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
Treatment
  • BTX-A51
  • D4476
  • siRNA
ATM (human) SHFDEVksIANQIQE S1270-p
ATM (mouse) SHFDEVKSIANQIQK S1273
ATM (rat) KHFDEVKSIANQIQR S1278
K1280-ub
NQIQEDWkSLLTDCF
0 1
ATM (human) NQIQEDWkSLLTDCF K1280-ub
ATM (mouse) NQIQKCWKSLLVDCF K1283
ATM (rat) NQIQRCWKSLLIDCF K1288
K1317-ub
QQRETATkVYDMLkS
0 2
ATM (human) QQRETATkVYDMLkS K1317-ub
ATM (mouse) QKRETATKVYDTLkG K1320
ATM (rat) QKRETATEVYDTLKG E1325
K1323-ub
TkVYDMLkSENLLGK
0 3
ATM (human) TkVYDMLkSENLLGK K1323-ub
ATM (mouse) TKVYDTLkGEDFLGK K1326-ub
ATM (rat) TEVYDTLKGEDFLGK K1331
T1363
NSSASQSTDLCDFSG
0 1
ATM (human) NSSASQSTDLCDFSG T1363
ATM (mouse) SDASQSAtALCDFSG T1370-p
ATM (rat) gap -
K1398-ub
AYISNCHkTKLKsIL
0 1
ATM (human) AYISNCHkTKLKsIL K1398-ub
ATM (mouse) AYISNCHKTKFKSIL K1405
ATM (rat) AYISSCHKTKFKSIL K1406
S1403-p
CHkTKLKsILEILSk
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • AurB (human)
Putative in vivo kinases:
  • AurB (human)
Treatment
  • hesperadin
  • ionizing_radiation
  • nocodazole
  • siRNA
ATM (human) CHkTKLKsILEILSk S1403-p
ATM (mouse) CHKTKFKSILEILSK S1410
ATM (rat) CHKTKFKSILEILSK S1411
K1410-ub
sILEILSkSPDSYQK
0 1
ATM (human) sILEILSkSPDSYQK K1410-ub
ATM (mouse) SILEILSKIPDsyQK K1417
ATM (rat) SILEILSKIPDSYQK K1418
S1414
ILSkSPDSYQKILLA
0 1
ATM (human) ILSkSPDSYQKILLA S1414
ATM (mouse) ILSKIPDsyQKILLA S1421-p
ATM (rat) ILSKIPDSYQKILLA S1422
Y1415
LSkSPDSYQKILLAI
0 1
ATM (human) LSkSPDSYQKILLAI Y1415
ATM (mouse) LSKIPDsyQKILLAI Y1422-p
ATM (rat) LSKIPDSYQKILLAI Y1423
K1572-ub
FPDHVVFkDLRITQQ
Upstream
0 4
Treatment
  • MG132
ATM (human) FPDHVVFkDLRITQQ K1572-ub
ATM (mouse) FPDHVIFKDLRLTQQ K1578
ATM (rat) FPDHVVFKDLRLTQQ K1579
K1580-ub
DLRITQQkIKYSRGP
0 1
ATM (human) DLRITQQkIKYSRGP K1580-ub
ATM (mouse) DLRLTQQKIKYSGGP K1586
ATM (rat) DLRLTQQKIKYSGGP K1587
K1615-ub
LTRLEGLkDLRRQLE
0 3
ATM (human) LTRLEGLkDLRRQLE K1615-ub
ATM (mouse) LTRLEGLKDLRRQLE K1621
ATM (rat) LTRLEGLKDLRRQLE K1622
K1625-ub
RRQLELHkDQMVDIM
0 3
ATM (human) RRQLELHkDQMVDIM K1625-ub
ATM (mouse) RRQLEQHKDQMLDLL K1631
ATM (rat) RRQLEQHKDQMLDLV K1632
S1655-p
VVNLLQLskMAINHt
0 2
ATM (human) VVNLLQLskMAINHt S1655-p
ATM (mouse) VVSLLQLSKMAVNQT S1661
ATM (rat) VVSLLQLSKMAVNQT S1662
K1656-m1
VNLLQLskMAINHtG
0 1
ATM (human) VNLLQLskMAINHtG K1656-m1
ATM (mouse) VSLLQLSKMAVNQTG K1662
ATM (rat) VSLLQLSKMAVNQTG K1663
K1656-ub
VNLLQLskMAINHtG
0 1
ATM (human) VNLLQLskMAINHtG K1656-ub
ATM (mouse) VSLLQLSKMAVNQTG K1662
ATM (rat) VSLLQLSKMAVNQTG K1663
T1662-p
skMAINHtGEkEVLE
0 1
ATM (human) skMAINHtGEkEVLE T1662-p
ATM (mouse) SKMAVNQTGEREVLE T1668
ATM (rat) SKMAVNQTGEREVLE T1669
K1665-ub
AINHtGEkEVLEAVG
0 1
ATM (human) AINHtGEkEVLEAVG K1665-ub
ATM (mouse) AVNQTGEREVLEAVG R1671
ATM (rat) AVNQTGEREVLEAVG R1672
S1673-p
EVLEAVGsCLGEVGP
0 1
ATM (human) EVLEAVGsCLGEVGP S1673-p
ATM (mouse) EVLEAVGRCLGEIGP R1679
ATM (rat) EVLEAVGRCLGEIGP R1680
K1692-ub
TIAIQHSkDASYTkA
0 1
ATM (human) TIAIQHSkDASYTkA K1692-ub
ATM (mouse) TIAVQHNKDVSYTKA K1698
ATM (rat) TIAVQHSKDTPYTKA K1699
K1698-ub
SkDASYTkALkLFED
0 2
ATM (human) SkDASYTkALkLFED K1698-ub
ATM (mouse) NKDVSYTKAYGLPED K1704
ATM (rat) SKDTPYTKAYGLPED K1705
K1701-ub
ASYTkALkLFEDKEL
0 1
ATM (human) ASYTkALkLFEDKEL K1701-ub
ATM (mouse) VSYTKAYGLPEDREL G1707
ATM (rat) TPYTKAYGLPEDREL G1708
Y1717-p
WTFIMLTyLNNTLVE
0 1
ATM (human) WTFIMLTyLNNTLVE Y1717-p
ATM (mouse) WTLIMLTALNNTLVE A1723
ATM (rat) WTLIMLTALNNTLVE A1724
K1738-ub
SAAVTCLkNILATkT
0 2
ATM (human) SAAVTCLkNILATkT K1738-ub
ATM (mouse) SAAATCLKNILATKI K1744
ATM (rat) SAAATCLKNILATKT K1745
K1744-ub
LkNILATkTGHSFWE
0 1
ATM (human) LkNILATkTGHSFWE K1744-ub
ATM (mouse) LKNILATKIGHIFWE K1750
ATM (rat) LKNILATKTGHIFWE K1751
Y1753-p
GHSFWEIyKMTTDPM
0 2
ATM (human) GHSFWEIyKMTTDPM Y1753-p
ATM (mouse) GHIFWENYKTSADPM Y1759
ATM (rat) GHIFWENHKTSADPM H1760
Y1763-p
TTDPMLAyLQPFRTS
0 3
ATM (human) TTDPMLAyLQPFRTS Y1763-p
ATM (mouse) SADPMLTYLQPFRTS Y1769
ATM (rat) SADPMLTYLQPFRAS Y1770
K1773-ub
PFRTSRKkFLEVPRF
0 1
ATM (human) PFRTSRKkFLEVPRF K1773-ub
ATM (mouse) PFRTSRKKFLEVPRS K1779
ATM (rat) PFRASRKKFLELPQF K1780
K1782-ub
LEVPRFDkENPFEGL
0 1
ATM (human) LEVPRFDkENPFEGL K1782-ub
ATM (mouse) LEVPRSVKEDVLEGL K1788
ATM (rat) LELPQFVKEDALEGL K1789
K1828-ub
CEILQLLkPMCEVKT
0 1
ATM (human) CEILQLLkPMCEVKT K1828-ub
ATM (mouse) SEILQLLKPMCEVKT K1834
ATM (rat) SEILQLLKPMCEVKT K1835
S1878-p
TSCLRHFsQTSRsTt
0 2
ATM (human) TSCLRHFsQTSRsTt S1878-p
ATM (mouse) TSCFKHSSQASRSAt S1884
ATM (rat) TNCFKHSSQASRSAt S1885
S1883-p
HFsQTSRsTtPANLD
0 1
ATM (human) HFsQTSRsTtPANLD S1883-p
ATM (mouse) HSSQASRSAtPANSD S1889
ATM (rat) HSSQASRSAtPANsD S1890
T1885-p
sQTSRsTtPANLDsE
Upstream
1 9
Kinase, in vitro:
  • ATM (human)
Treatment
  • ionizing_radiation
ATM (human) sQTSRsTtPANLDsE T1885-p
ATM (mouse) SQASRSAtPANSDsE T1891-p
ATM (rat) SQASRSAtPANsDSE T1892-p
L1889
RsTtPANLDsEsEHF
0 1
ATM (human) RsTtPANLDsEsEHF L1889
ATM (mouse) RSAtPANSDsEsENF S1895
ATM (rat) RSAtPANsDSESENF S1896-p
S1891-p
TtPANLDsEsEHFFR
Upstream
Downstream
4 6
Effects on Biological Processes:
  • carcinogenesis, inhibited
Regulatory protein:
  • ATM (human)
  • C9orf72 (human)
Treatment
  • ionizing_radiation
  • KU-55933
  • nutlin-3
  • RITA
  • topotecan
ATM (human) TtPANLDsEsEHFFR S1891-p
ATM (mouse) AtPANSDsEsENFLR S1897-p
ATM (rat) AtPANsDSESENFLR S1898
S1893-p
PANLDsEsEHFFRCC
Upstream
3 3
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
  • KU-55933
  • wortmannin
ATM (human) PANLDsEsEHFFRCC S1893-p
ATM (mouse) PANSDsEsENFLRCC S1899-p
ATM (rat) PANsDSESENFLRCC S1900
T1908-p
LDKKSQRtMLAVVDy
0 1
ATM (human) LDKKSQRtMLAVVDy T1908-p
ATM (mouse) LDKKSQRTMLAVVDY T1914
ATM (rat) LDKKSQRTMLAVVDY T1915
Y1915-p
tMLAVVDyMRRQKRP
0 1
ATM (human) tMLAVVDyMRRQKRP Y1915-p
ATM (mouse) TMLAVVDYLRRQKRP Y1921
ATM (rat) TMLAVVDYLRRQKRP Y1922
S1974-p
MDDQEKRsLAFEEGs
1 1
ATM (human) MDDQEKRsLAFEEGs S1974-p
ATM (mouse) TDEQEKRSPTFEEGs S1980
ATM (rat) MDEQEKRsPTFEEGs S1981-p
S1981-p
sLAFEEGsQSTtIss
Upstream
Downstream
215 28
ATM (human)
S1981-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, altered
  • DNA repair, induced
  • apoptosis, altered
  • apoptosis, induced
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, altered
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell growth, induced
  • chromatin organization, altered
  • signaling pathway regulation
  • transcription, altered
Kinase, in vitro:
  • ATM (human)
  • ATR (human)
Phosphatases, in vitro:
  • PPM1D (human)
Putative in vivo kinases:
  • ATM (human)
  • ATR (human)
Putative upstream phosphatases:
  • PPM1D (mouse)
  • PPP2CA (human)
Regulatory protein:
  • 53BP1 (human)
  • AML2 (human)
  • AMPKA1 (human)
  • ATM (human)
  • ATR (human)
  • AVEN (human)
  • Bcl-2 (human)
  • BLM (human)
  • BMI1 (human)
  • BRCA1 (human)
  • CASP2 (human)
  • CDCA2 (human)
  • CDK1 (human)
  • Chk1 (human)
  • CtIP (human)
  • EDEM1 (human)
  • ERK1 (human)
  • ERK2 (human)
  • FANCA (human)
  • H2AX (human)
  • HMGA2 (human)
  • IkB-alpha (human)
  • IKKG (human)
  • KHDRBS1 (human)
  • lamin A/C (human)
  • MCT1 (human)
  • MEK5 (human)
  • MKK3 (human)
  • MPG (human)
  • MRE11A (human)
  • MST1 (human)
  • NBS1 (human)
  • NKX3-1 (human)
  • OBFC2B (human)
  • p14ARF (human)
  • P38A (human)
  • p53 (human)
  • PARG (human)
  • PDE1A (human)
  • PPA1 (human)
  • PPM1D (human)
  • PPM1D (mouse)
  • PPP4C (human)
  • RACK7 (human)
  • RAD17 (human)
  • RNF8 (human)
  • SAMHD1 (human)
  • SMEK2 (human)
  • SMG8 (human)
  • SMG9 (human)
  • SOCS1 (human)
  • SOD2 (human)
  • Tip60 (human)
  • TRF2 (human)
  • TXN (human)
  • ULK1 (human)
  • VCP (human)
  • WSTF (human)
  • XRCC1 (human)
  • YAP1 (human)
Treatment
  • 4-HT
  • 5-aza-CdR
  • adriamycin
  • aminoguanidine
  • aminothiazole_compound_25
  • AP21967
  • arsenic
  • arsenite
  • ATM_inhibitor
  • axitinib
  • AZ20
  • AZD0156
  • berzosertib
  • beta-lapachone
  • BIBX
  • bleomycin
  • BMP4
  • Boc-D-FMK
  • bornyl_acetate
  • caffeine
  • camptothecin
  • CBP-93872
  • CDT
  • celecoxib
  • cell_adhesion
  • ceritinib
  • chloroquine
  • cigarette_smoke
  • colforsin
  • CPT
  • cycloheximide
  • cyclophosphamide
  • cytarabine
  • dactolisib
  • dexamethasone
  • dorsomorphin
  • DSBs
  • dsDNA
  • ER_27319
  • Et743
  • etoposide
  • flupenthixol
  • galiellalactone
  • gefitinib
  • gemcitabine
  • genistein
  • Go_6976
  • granzyme_B
  • grape_seed_extract
  • H2O2
  • hydroxycamptothecin
  • hydroxyurea
  • hypotonic_buffer
  • IBMX
  • IC86621
  • ICRF-193
  • indisulam
  • Inotuzumab-ozogamicin
  • ionizing_radiation
  • irofulven
  • KU-55933
  • KU-60019
  • Ku-DNA binding inhibitor
  • lncRNAs
  • lurbinectedin
  • LY294002
  • M3541
  • methotrexate
  • MI-63
  • miR-16
  • miRNA
  • mitomycin_C
  • mitoxantrone
  • MMS
  • MS275
  • mutation
  • NaB
  • NAC
  • NB-598
  • neocarzinostatin
  • neratinib
  • niraparib
  • nocodazole
  • NU7026
  • NU7441
  • nutlin-3
  • okadaic_acid
  • olaparib
  • PD184352
  • PDTC
  • PHA-767491
  • phleomycin
  • phorbol_ester
  • pifithrin-alpha
  • PLX4720
  • quizartinib
  • rapamycin
  • retinoic_acid
  • Ro31-8220
  • romidepsin
  • ryuvidine
  • S-valproate
  • SB203580
  • SCH772984
  • seliciclib
  • silibinin
  • siRNA
  • sorafenib
  • TAK-475
  • terbinafine
  • thymidine
  • ticarcillin
  • TMZ
  • topotecan
  • trichostatin_A
  • triphala
  • troxacitabine
  • UV
  • valproic acid
  • VE-821
  • venetoclax
  • virus infection
  • vorinostat
  • VRX0466617
  • wortmannin
  • Z-VAD-FMK
  • Zeocin
ATM (human) sLAFEEGsQSTtIss S1981-p
ATM (mouse) SPTFEEGsQGTTIsS S1987-p
ATM (rat) sPTFEEGsQGTTISS S1988-p
T1985-p
EEGsQSTtIssLSEk
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
ATM (human) EEGsQSTtIssLSEk T1985-p
ATM (mouse) EEGsQGTTIsSLSEK T1991
ATM (rat) EEGsQGTTISSLSEK T1992
S1987-p
GsQSTtIssLSEksk
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
ATM (human) GsQSTtIssLSEksk S1987-p
ATM (mouse) GsQGTTIsSLSEKSK S1993-p
ATM (rat) GsQGTTISSLSEKSK S1994
S1988-p