Other Species / Isoforms
  ERK2 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y23
VFDVGPRYTNLSYIG
0 1
ERK2 (human) VFDVGPRyTNLsYIG Y25-p
ERK2 (mouse) VFDVGPRYTNLSYIG Y23
ERK2 (rat) VFDVGPRYTNLsyIG Y23
ERK2 (chicken) VFDVGPRYTNLSYIG Y33
ERK2 (cow) VFDVGPRYTNLSYIG Y25
S27
GPRYTNLSYIGEGAY
1 0
ERK2 (human) GPRyTNLsYIGEGAy S29-p
ERK2 (mouse) GPRYTNLSYIGEGAY S27
ERK2 (rat) GPRYTNLsyIGEGAY S27-p
ERK2 (chicken) GPRYTNLSYIGEGAY S37
ERK2 (cow) GPRYTNLSYIGEGAY S29
Y28
PRYTNLSYIGEGAYG
0 1
ERK2 (human) PRyTNLsYIGEGAyG Y30
ERK2 (mouse) PRYTNLSYIGEGAYG Y28
ERK2 (rat) PRYTNLsyIGEGAYG Y28-p
ERK2 (chicken) PRYTNLSYIGEGAYG Y38
ERK2 (cow) PRYTNLSYIGEGAYG Y30
Y34
SYIGEGAYGMVCSAY
0 3
ERK2 (human) sYIGEGAyGMVCSAy Y36-p
ERK2 (mouse) SYIGEGAYGMVCSAY Y34
ERK2 (rat) syIGEGAYGMVCSAy Y34
ERK2 (chicken) SYIGEGAYGMVCSAY Y44
ERK2 (cow) SYIGEGAYGMVCSAY Y36
Y41
YGMVCSAYDNLNKVR
0 7
ERK2 (human) yGMVCSAyDNVNKVR Y43-p
ERK2 (mouse) YGMVCSAYDNLNKVR Y41
ERK2 (rat) YGMVCSAyDNLNKVR Y41-p
ERK2 (chicken) YGMVCSAYDNVNKVR Y51
ERK2 (cow) YGMVCSAYDNVNKVR Y43
K53
KVRVAIKKISPFEHQ
0 3
ERK2 (human) KVRVAIKkISPFEHQ K55-ub
ERK2 (mouse) KVRVAIKKISPFEHQ K53
ERK2 (rat) KVRVAIKKISPFEHQ K53
ERK2 (chicken) KVRVAIKKISPFEHQ K63
ERK2 (cow) KVRVAIKKISPFEHQ K55
K97
APTIEQMKDVYIVQD
0 1
ERK2 (human) APTIEQMkDVYIVQD K99-ub
ERK2 (mouse) APTIEQMKDVYIVQD K97
ERK2 (rat) APTIEQMKDVYIVQD K97
ERK2 (chicken) APTIEQMKDVYIVQD K107
ERK2 (cow) APTIEQMKDVYIVQD K99
Y111
DLMETDLYKLLKTQH
0 3
ERK2 (human) DLMETDLyKLLKTQH Y113-p
ERK2 (mouse) DLMETDLYKLLKTQH Y111
ERK2 (rat) DLMETDLYKLLKTQH Y111
ERK2 (chicken) DLMETDLYKLLKTQH Y121
ERK2 (cow) DLMETDLYKLLKTQH Y113
S140
RGLKYIHSANVLHRD
0 1
ERK2 (human) RGLKYIHsANVLHRD S142-p
ERK2 (mouse) RGLKYIHSANVLHRD S140
ERK2 (rat) RGLKYIHSANVLHRD S140
ERK2 (chicken) RGLKYIHSANVLHRD S150
ERK2 (cow) RGLKYIHSANVLHRD S142
K149-ub
NVLHRDLkPSNLLLN
0 3
ERK2 (human) NVLHRDLkPSNLLLN K151-ub
ERK2 (mouse) NVLHRDLkPSNLLLN K149-ub
ERK2 (rat) NVLHRDLKPSNLLLN K149
ERK2 (chicken) NVLHRDLKPSNLLLN K159
ERK2 (cow) NVLHRDLKPSNLLLN K151
K162
LNTTCDLKICDFGLA
0 1
ERK2 (human) LNTTCDLkICDFGLA K164-ub
ERK2 (mouse) LNTTCDLKICDFGLA K162
ERK2 (rat) LNTTCDLKICDFGLA K162
ERK2 (chicken) LNTTCDLKICDFGLA K172
ERK2 (cow) LNTTCDLKICDFGLA K164
T179-p
ADPDHDHtGFLtEyV
Upstream
3 51
Treatment
  • GM-CSF
  • LPA
ERK2 (human) ADPDHDHtGFLtEyV T181-p
ERK2 (mouse) ADPDHDHtGFLtEyV T179-p
ERK2 (rat) ADPDHDHtGFLtEyV T179-p
ERK2 (chicken) ADPDHDHTGFLTEYV T189
ERK2 (cow) ADPDHDHTGFLtEyV T181
T183-p
HDHtGFLtEyVAtRW
Upstream
Downstream
1098 2523
ERK2 (human)
T185-p
ERK2 (mouse)
T183-p
ERK2 (rat)
T183-p
ERK2 (chicken)
T193-p
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • cytoskeletal reorganization
  • neural plasticity
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • MEK1 (human)
  • MEK1 (mouse)
  • MEK1 (rabbit)
  • MEK1 (rat)
Putative in vivo kinases:
  • MEK1 (human)
  • MEK1 (mouse)
Putative upstream phosphatases:
  • PPP2CA (mouse)
Regulatory protein:
  • AIF1 (mouse)
  • Akt1 (mouse)
  • ALK (human)
  • ARAF (human)
  • ARAF (mouse)
  • ARHGEF7 (mouse)
  • ARRB1 (mouse)
  • BAG1 (mouse)
  • Bcl-10 (mouse)
  • BCR-ABL1 (human)
  • BRAF (human)
  • BRAF iso1 (mouse)
  • Brk (mouse)
  • CAMK2D (human)
  • CARD11 (mouse)
  • CARD9 (mouse)
  • CBL (mouse)
  • Cbl-b (mouse)
  • CD151 (mouse)
  • CD44 (mouse)
  • CD74 (mouse)
  • CDC42 (mouse)
  • CDC42 iso1 (mouse)
  • CDK5R1 (mouse)
  • Cot (human)
  • Cot (mouse)
  • dectin-1 (mouse)
  • DLG3 (mouse)
  • DOK3 (mouse)
  • DRD1 (mouse)
  • DUSP19 (mouse)
  • DUSP3 (mouse)
  • DUSP6 (mouse)
  • EAR-2 (mouse)
  • EGFR (mouse)
  • ERG (mouse)
  • ERK2 (mouse)
  • FADD (mouse)
  • FAK iso2 (mouse)
  • FAK iso9 (mouse)
  • FCER1A (mouse)
  • Fes (mouse)
  • FGFR1 (human)
  • FLT3 (human)
  • FMR1 (mouse)
  • FOXO1A (mouse)
  • FOXP1 (mouse)
  • G-alpha i2 (human)
  • G-beta 1 (mouse)
  • GAB2 (mouse)
  • GIPC1 (mouse)
  • GIT1 (human)
  • GLRX1 (mouse)
  • GRB10 (human)
  • GRB10 (mouse)
  • HePTP (mouse)
  • HRas (mouse)
  • ICMT (mouse)
  • IGF1R (mouse)
  • IL17RD (mouse)
  • IRS1 (mouse)
  • ITGA9 (human)
  • JAK2 (human)
  • JNK2 (mouse)
  • KRas (mouse)
  • KSR (human)
  • LAB (mouse)
  • LAT (mouse)
  • MAPKAPK2 (mouse)
  • MAPKAPK3 (mouse)
  • MEK1 (mouse)
  • MEKK1 (mouse)
  • mGluR5 (mouse)
  • MIEN1 (human)
  • MRas (human)
  • MSK1 (human)
  • MSK1 (mouse)
  • MSK2 (mouse)
  • MST1 (human)
  • neurogranin (mouse)
  • NPC1 (mouse)
  • NPM1 (human)
  • NYAP2 (mouse)
  • PAG (rat)
  • PAK1 (human)
  • PAK4 (mouse)
  • PDGFRA (mouse)
  • PDK1 (mouse)
  • PELI1 (mouse)
  • PHLPP (human)
  • PHLPP2 (human)
  • PKCA (mouse)
  • PKCT (mouse)
  • PPP1CC (human)
  • PRKD1 (mouse)
  • PRMT5 (human)
  • PRMT5 (mouse)
  • PRMT5 (rat)
  • PTEN (mouse)
  • PTP1B (mouse)
  • PTPRB (mouse)
  • PTPRJ (mouse)
  • PTPRM (mouse)
  • RAB11A (mouse)
  • Rab7 (mouse)
  • RAC1 (mouse)
  • RAF1 (human)
  • RAF1 (mouse)
  • RAIG1 (mouse)
  • Ret (human)
  • RHOC (mouse)
  • RICTOR (mouse)
  • ROCK1 (mouse)
  • SGPL1 (mouse)
  • SH3BP2 (mouse)
  • SHC1 iso2 (human)
  • SHP-2 (mouse)
  • Src (human)
  • Src iso1 (mouse)
  • Syk (mouse)
  • syndecan-4 (mouse)
  • TAK1 (mouse)
  • TBK1 (mouse)
  • Tel (human)
  • TSC2 (mouse)
  • UCP2 (mouse)
  • VEGFR3 (mouse)
  • Vinculin (mouse)
  • ZAP70 (mouse)
Treatment
  • 15d-PGJ2
  • 17-beta-estradiol
  • 1Na-PP1
  • 22-hydroxycholesterol
  • 5'-methylthioadenosine
  • 8-(3-chlorostyryl) caffeine
  • 9d
  • A23187
  • acadesine
  • adriamycin
  • AG1296
  • AG1478
  • AG490
  • AGEs
  • Akt-I-1
  • Akt_activator_compound_11
  • Akt_inhibitor_VIII
  • alloxazine
  • alpha-lipoic_acid
  • amino_acid_starvation
  • amino_acids
  • amphoterin
  • angiopoietin-1
  • angiopoietin-2
  • anisomycin
  • anti-CD3
  • anti-CD3/CD28
  • anti-CD4
  • anti-CD8
  • anti-Fas
  • anti-IgB
  • anti-IgE
  • anti-IgM
  • anti-ITGA4
  • anti-ITGA6
  • anti-ITGB3
  • antichymotrypsin
  • antigenic stimulation
  • antitrypsin
  • aphidicolin
  • apigenin
  • apomorphine
  • atorvastatin
  • bacterial infection
  • BAPTA-AM
  • Bay61-3606
  • BDNF
  • benzo(a)pyrene
  • beta-amyloid_40
  • betaxolol
  • BFD-22
  • BI-D1870
  • bicuculline
  • BIRA766
  • BIRB-0796
  • bisindolylmaleimide
  • black_tea_polyphenols
  • bombesin
  • bradykinin
  • BRL37344
  • caffeine
  • calphostin_C
  • calyculin_A
  • cAMP_analog
  • cell_adhesion
  • cell_detachment
  • CGP77675
  • CGS_21680
  • chelerythrine
  • ciclopirox_olamine
  • cocaine
  • cold_water_stress
  • colforsin
  • compound_56
  • compound_6
  • ConA
  • curcumin
  • curdlan
  • CXCL12
  • cyclic_stretch
  • cycloheximide
  • cytochalasin_D
  • dactolisib
  • DDA
  • depolarization
  • desmopressin
  • dexamethasone
  • DHPG
  • differentiation
  • DMNQ
  • DNP
  • DPCPX
  • dronabinol
  • EDTA
  • EGF
  • EGTA
  • Epo
  • epoxomicin
  • estradiol
  • ethanol
  • ether
  • faslodex
  • fedratinib
  • FGF1
  • FGF2
  • fibronectin
  • fingolimod
  • fisetin
  • FL
  • fluid_shear_stress
  • food deprivation
  • G-CSF
  • GDNF
  • gefitinib
  • gelatin
  • GF109203X
  • GH
  • GLP-1
  • glucose
  • GM-CSF
  • GnRH
  • Go_6976
  • guanosine
  • GW4869
  • H-89
  • H2O2
  • haloperidol
  • heparin sodium
  • herstatin
  • HGF
  • honokiol
  • hypertonic_buffer
  • hypoxia
  • IBMX
  • ICI-118,551
  • IFN-alpha
  • IFN-gamma
  • IgE
  • IGF-1
  • IGF-2
  • IL-18
  • IL-1b
  • IL-3
  • IL-33
  • IL-4
  • IL-6
  • IL-9
  • imatinib
  • insulin
  • ionomycin
  • ischemia/reperfusion
  • isoflurane
  • isoproterenol
  • iturelix
  • JNK_inhibitor_I
  • kainic_acid
  • ketamine
  • KN-93
  • KT5823
  • L-744,832
  • L-NAME
  • laminin-1
  • leptin
  • leucine
  • levamfetamine
  • licochalcone_A
  • licochalcone_B
  • licochalcone_C
  • licochalcone_D
  • LIF
  • LIF withdrawal
  • light
  • lonafarnib
  • long-term_potentiation
  • low_glucose
  • LPA
  • LPS
  • LY294002
  • M-CSF
  • methotrexate
  • methyl-beta-cyclodextrin
  • methylphenidate
  • MG132
  • midazolam
  • MIF
  • miR-181a
  • MK801
  • MMS
  • MnTBAP
  • MPTP
  • MRS-1523
  • MSH
  • muramyl_dipeptide
  • NAC
  • nicotine
  • nifedipine
  • NMDA
  • nocodazole
  • nomifensine
  • NP68
  • NSC697923
  • NTCU
  • NVP-BKM120
  • ODQ
  • OH-BBN
  • okadaic_acid
  • orantinib
  • OVA
  • PACAP
  • palmitate
  • Pam3CSK4
  • papaverine
  • PAR1-activating_peptide
  • PD0325901
  • PD169316
  • PD184352
  • PD90059
  • PD98059
  • PDGF
  • peptones
  • PGE2
  • phorbol_ester
  • pilocarpine
  • PKC-theta_pseudosubstrate
  • poly-L-lysine
  • pomegranate_wine
  • PP1
  • PP2
  • prazosin
  • progestin_R5020
  • propofol
  • propranolol
  • PTX
  • racepinefrine
  • Raf1_kinase_inhibitor_I
  • RANKL
  • rapamycin
  • refeeding
  • restraint stress
  • resveratrol
  • retinoic_acid
  • RGD
  • RGE
  • rimonabant
  • rolipram
  • rosiglitazone
  • rottlerin
  • S107
  • SB202190
  • SB203580
  • SCF
  • SCH_23390
  • seliciclib
  • semaxanib
  • serum
  • serum_withdrawal
  • silibinin
  • silymarin
  • siRNA
  • SKF82958
  • SL0101
  • SL327
  • SMI11293
  • sorbitol
  • SP600125
  • sphingomyelin
  • sphingosine_1-phosphate
  • SPT
  • staurosporine
  • streptozotocin
  • SU5402
  • SU6656
  • sunitinib
  • TAK1_inhibitor
  • TCAP-1
  • TCDD
  • TDZD-8
  • TGF-alpha
  • TGF-beta
  • Theophylline
  • thrombin
  • thrombospondin
  • TNF
  • Torin1
  • triciribine
  • TTX
  • TUG-891
  • U0126
  • urethane
  • UV
  • vasopressin
  • VEGF
  • visual experience
  • vitronectin
  • WIN
  • wortmannin
  • Y27632
  • YM-254890
  • yohimbine
  • Zn(2+)
  • zymosan
ERK2 (human) HDHtGFLtEyVAtRW T185-p
ERK2 (mouse) HDHtGFLtEyVAtRW T183-p
ERK2 (rat) HDHtGFLtEyVAtRW T183-p
ERK2 (chicken) HDHTGFLTEYVATRW T193
ERK2 (cow) HDHTGFLtEyVATRW T185-p
Y185-p
HtGFLtEyVAtRWYR
Upstream
Downstream
1121 4135
ERK2 (human)
Y187-p
ERK2 (mouse)
Y185-p
ERK2 (rat)
Y185-p
ERK2 (chicken)
Y195-p
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • cytoskeletal reorganization
  • neural plasticity
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • ERK2 (mouse)
  • ERK2 (rat)
  • Lck (mouse)
  • MEK1 (human)
  • MEK1 (mouse)
  • MEK1 (rabbit)
  • MEK1 (rat)
Putative in vivo kinases:
  • MEK1 (human)
  • MEK1 (mouse)
Putative upstream phosphatases:
  • PPP2CA (mouse)
Regulatory protein:
  • AIF1 (mouse)
  • Akt1 (mouse)
  • ALK (human)
  • ARAF (human)
  • ARAF (mouse)
  • ARHGEF7 (mouse)
  • ARRB1 (mouse)
  • BAG1 (mouse)
  • Bcl-10 (mouse)
  • BCR-ABL1 (human)
  • BRAF (human)
  • BRAF iso1 (mouse)
  • Brk (mouse)
  • CAMK2D (human)
  • CARD11 (mouse)
  • CARD9 (mouse)
  • CBL (mouse)
  • Cbl-b (mouse)
  • CD151 (mouse)
  • CD44 (mouse)
  • CD74 (mouse)
  • CDC42 iso1 (mouse)
  • CDK5R1 (mouse)
  • Cot (human)
  • Cot (mouse)
  • dectin-1 (mouse)
  • DLG3 (mouse)
  • DOK3 (mouse)
  • DRD1 (mouse)
  • DUSP19 (mouse)
  • DUSP3 (mouse)
  • DUSP6 (mouse)
  • EAR-2 (mouse)
  • EGFR (mouse)
  • eNOS (mouse)
  • ERG (mouse)
  • ERK2 (mouse)
  • FADD (mouse)
  • FAK iso2 (mouse)
  • FAK iso9 (mouse)
  • FCER1A (mouse)
  • Fes (mouse)
  • FGFR1 (human)
  • FGFR2 (human)
  • FLT3 (human)
  • FLT3 (mouse)
  • FMR1 (mouse)
  • FOXO1A (mouse)
  • FOXP1 (mouse)
  • G-alpha i2 (human)
  • G-beta 1 (mouse)
  • GAB2 (mouse)
  • GIPC1 (mouse)
  • GIT1 (human)
  • GLRX1 (mouse)
  • GRB10 (human)
  • GRB10 (mouse)
  • HePTP (mouse)
  • HRas (mouse)
  • ICMT (mouse)
  • IGF1R (mouse)
  • IL17RD (mouse)
  • IRS1 (mouse)
  • ITGA9 (human)
  • JAK2 (human)
  • JNK2 (mouse)
  • KRas (mouse)
  • KSR (human)
  • LAB (mouse)
  • LAT (mouse)
  • MAPKAPK2 (mouse)
  • MAPKAPK3 (mouse)
  • MEK1 (mouse)
  • MEKK1 (mouse)
  • mGluR5 (mouse)
  • MIEN1 (human)
  • MRas (human)
  • MSK1 (human)
  • MSK1 (mouse)
  • MSK2 (mouse)
  • MST1 (human)
  • neurogranin (mouse)
  • NPC1 (mouse)
  • NPM1 (human)
  • NYAP2 (mouse)
  • PAG (rat)
  • PAK1 (human)
  • PDGFRA (mouse)
  • PDK1 (mouse)
  • PELI1 (mouse)
  • PHLPP (human)
  • PHLPP2 (human)
  • PKCA (mouse)
  • PKCT (mouse)
  • PPP1CC (human)
  • PRKD1 (mouse)
  • PRMT5 (human)
  • PRMT5 (mouse)
  • PRMT5 (rat)
  • PTEN (mouse)
  • PTP1B (mouse)
  • PTPRB (mouse)
  • PTPRJ (mouse)
  • PTPRM (mouse)
  • RAB11A (mouse)
  • Rab7 (mouse)
  • RAC1 (mouse)
  • RAF1 (human)
  • RAF1 (mouse)
  • RAIG1 (mouse)
  • Ret (human)
  • RHOC (mouse)
  • ROCK1 (mouse)
  • SGPL1 (mouse)
  • SH3BP2 (mouse)
  • SHC1 iso2 (human)
  • SHP-2 (mouse)
  • Src (human)
  • Src iso1 (mouse)
  • Syk (mouse)
  • syndecan-4 (mouse)
  • TAK1 (mouse)
  • TBK1 (mouse)
  • Tel (human)
  • TSC2 (mouse)
  • UCP2 (mouse)
  • VEGFR3 (mouse)
  • Vinculin (mouse)
  • ZAP70 (mouse)
Treatment
  • 15d-PGJ2
  • 17-beta-estradiol
  • 1Na-PP1
  • 22-hydroxycholesterol
  • 5'-methylthioadenosine
  • 8-(3-chlorostyryl) caffeine
  • 9d
  • A23187
  • acadesine
  • adriamycin
  • AG1296
  • AG1478
  • AG490
  • AGEs
  • Akt-I-1
  • Akt_activator_compound_11
  • Akt_inhibitor_VIII
  • alloxazine
  • alpha-lipoic_acid
  • amino_acid_starvation
  • amino_acids
  • amphoterin
  • angiopoietin-1
  • angiopoietin-2
  • anisomycin
  • anti-CD3
  • anti-CD3/CD28
  • anti-CD4
  • anti-CD8
  • anti-Fas
  • anti-IgB
  • anti-IgE
  • anti-IgM
  • anti-ITGA4
  • anti-ITGA6
  • anti-ITGB3
  • antichymotrypsin
  • antigenic stimulation
  • antitrypsin
  • aphidicolin
  • apigenin
  • apomorphine
  • atorvastatin
  • bacterial infection
  • BAPTA-AM
  • Bay61-3606
  • BDNF
  • benzo(a)pyrene
  • beta-amyloid_40
  • betaxolol
  • BFD-22
  • BI-D1870
  • bicuculline
  • BIRA766
  • BIRB-0796
  • bisindolylmaleimide
  • black_tea_polyphenols
  • bombesin
  • bradykinin
  • brefeldin_A
  • BRL37344
  • caffeine
  • calphostin_C
  • calyculin_A
  • cAMP_analog
  • cell_adhesion
  • cell_detachment
  • CGP77675
  • CGS_21680
  • chelerythrine
  • ciclopirox_olamine
  • cocaine
  • cold_water_stress
  • colforsin
  • compound_56
  • compound_6
  • ConA
  • curcumin
  • curdlan
  • CXCL12
  • cyclic_stretch
  • cycloheximide
  • cytochalasin_D
  • dactolisib
  • DDA
  • depolarization
  • desmopressin
  • DETA-NONOate
  • dexamethasone
  • DHPG
  • differentiation
  • DMNQ
  • DNP
  • DPCPX
  • DPDPE
  • dronabinol
  • DTLET
  • EDTA
  • EGF
  • EGTA
  • Epo
  • epoxomicin
  • estradiol
  • ethanol
  • ether
  • faslodex
  • fedratinib
  • FGF1
  • FGF2
  • fibronectin
  • fingolimod
  • fisetin
  • FL
  • fluid_shear_stress
  • food deprivation
  • G-CSF
  • GDNF
  • gefitinib
  • gelatin
  • GF109203X
  • GH
  • GLP-1
  • glucose
  • GnRH
  • Go_6976
  • guanosine
  • GW4869
  • H-89
  • H2O2
  • haloperidol
  • heparin sodium
  • herstatin
  • HGF
  • honokiol
  • hypertonic_buffer
  • hypoxia
  • IBMX
  • ICI-118,551
  • IFN-alpha
  • IFN-gamma
  • IgE
  • IGF-1
  • IGF-2
  • IL-18
  • IL-1b
  • IL-3
  • IL-33
  • IL-4
  • IL-6
  • IL-9
  • imatinib
  • insulin
  • ionomycin
  • ischemia/reperfusion
  • isoproterenol
  • iturelix
  • JNK_inhibitor_I
  • kainic_acid
  • KGF
  • KN-93
  • KT5823
  • L-744,832
  • L-NAME
  • laminin-1
  • leptin
  • leucine
  • levamfetamine
  • licochalcone_A
  • licochalcone_B
  • licochalcone_C
  • licochalcone_D
  • LIF
  • LIF withdrawal
  • light
  • lonafarnib
  • long-term_potentiation
  • low_glucose
  • LPA
  • LPS
  • LY294002
  • M-CSF
  • methotrexate
  • methyl-beta-cyclodextrin
  • methylphenidate
  • MG132
  • midazolam
  • MIF
  • miR-181a
  • MK801
  • MMS
  • MnTBAP
  • morphine
  • MPTP
  • MRS-1523
  • MSH
  • muramyl_dipeptide
  • NAC
  • nicotine
  • nifedipine
  • NMDA
  • nocodazole
  • nomifensine
  • NP68
  • NSC697923
  • NTCU
  • NVP-BKM120
  • ODQ
  • OH-BBN
  • okadaic_acid
  • orantinib
  • OVA
  • PACAP
  • palmitate
  • Pam3CSK4
  • papaverine
  • PAR1-activating_peptide
  • PD0325901
  • PD169316
  • PD184352
  • PD90059
  • PD98059
  • PDGF
  • peptones
  • PGE2
  • phorbol_ester
  • pilocarpine
  • PKC-theta_pseudosubstrate
  • PKC412
  • poly-L-lysine
  • pomegranate_wine
  • PP1
  • PP2
  • prazosin
  • progestin_R5020
  • propranolol
  • PTH(1-34)
  • PTX
  • racepinefrine
  • Raf1_kinase_inhibitor_I
  • RANKL
  • rapamycin
  • refeeding
  • restraint stress
  • resveratrol
  • retinoic_acid
  • RGD
  • RGE
  • rimonabant
  • rolipram
  • rosiglitazone
  • rottlerin
  • S107
  • SB202190
  • SB203580
  • SCF
  • SCH_23390
  • seliciclib
  • semaxanib
  • serum
  • serum_withdrawal
  • silibinin
  • silymarin
  • siRNA
  • SKF82958
  • SL0101
  • SL327
  • SMI11293
  • sorbitol
  • SP600125
  • sphingomyelin
  • sphingosine_1-phosphate
  • SPT
  • staurosporine
  • streptozotocin
  • SU5402
  • SU6656
  • sunitinib
  • TAK1_inhibitor
  • TCAP-1
  • TCDD
  • TDZD-8
  • TGF-alpha
  • TGF-beta
  • Theophylline
  • thrombin
  • thrombospondin
  • TNF
  • Torin1
  • triciribine
  • TTX
  • TUG-891
  • tunicamycin
  • U0126
  • urethane
  • UV
  • vasopressin
  • VEGF
  • visual experience
  • vitronectin
  • WIN
  • wortmannin
  • Y27632
  • YM-254890
  • yohimbine
  • Zn(2+)
  • zymosan
ERK2 (human) HtGFLtEyVAtRWyR Y187-p
ERK2 (mouse) HtGFLtEyVAtRWYR Y185-p
ERK2 (rat) HtGFLtEyVAtRWYR Y185-p
ERK2 (chicken) HTGFLTEYVATRWYR Y195
ERK2 (cow) HTGFLtEyVATRWYR Y187-p
T188-p
FLtEyVAtRWYRAPE
Upstream
Downstream
3 34
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell growth, altered
  • cytoskeletal reorganization
Treatment
  • heart failure
  • insulin
ERK2 (human) FLtEyVAtRWyRAPE T190-p
ERK2 (mouse) FLtEyVAtRWYRAPE T188-p
ERK2 (rat) FLtEyVAtRWYRAPE T188-p
ERK2 (chicken) FLTEYVATRWYRAPE T198
ERK2 (cow) FLtEyVATRWYRAPE T190
Y191
EyVAtRWYRAPEIML
0 5
ERK2 (human) EyVAtRWyRAPEIML Y193-p
ERK2 (mouse) EyVAtRWYRAPEIML Y191
ERK2 (rat) EyVAtRWYRAPEIML Y191
ERK2 (chicken) EYVATRWYRAPEIML Y201
ERK2 (cow) EyVATRWYRAPEIML Y193
K201-ub
PEIMLNSkGYTKSID
0 7
ERK2 (human) PEIMLNSkGytKSID K203-ub
ERK2 (mouse) PEIMLNSkGYTKSID K201-ub
ERK2 (rat) PEIMLNSKGytKSID K201
ERK2 (chicken) PEIMLNSKGYTKSID K211
ERK2 (cow) PEIMLNSKGYTKSID K203
Y203
IMLNSkGYTKSIDIW
1 1
ERK2 (human) IMLNSkGytKSIDIW Y205-p
ERK2 (mouse) IMLNSkGYTKSIDIW Y203
ERK2 (rat) IMLNSKGytKSIDIW Y203-p
ERK2 (chicken) IMLNSKGYTKSIDIW Y213
ERK2 (cow) IMLNSKGYTKSIDIW Y205
T204
MLNSkGYTKSIDIWS
1 1
ERK2 (human) MLNSkGytKSIDIWS T206-p
ERK2 (mouse) MLNSkGYTKSIDIWS T204
ERK2 (rat) MLNSKGytKSIDIWS T204-p
ERK2 (chicken) MLNSKGYTKSIDIWS T214
ERK2 (cow) MLNSKGYTKSIDIWS T206
S244
HILGILGSPSQEDLN
2 1
ERK2 (human) HILGILGsPsQEDLN S246-p
ERK2 (mouse) HILGILGSPSQEDLN S244
ERK2 (rat) HILGILGSPSQEDLN S244
ERK2 (chicken) HILGILGSPSQEDLN S254
ERK2 (cow) HILGILGSPSQEDLN S246
S246
LGILGSPSQEDLNCI
2 0
ERK2 (human) LGILGsPsQEDLNCI S248-p
ERK2 (mouse) LGILGSPSQEDLNCI S246
ERK2 (rat) LGILGSPSQEDLNCI S246
ERK2 (chicken) LGILGSPSQEDLNCI S256
ERK2 (cow) LGILGSPSQEDLNCI S248
K257-ub
LNCIINLkARNYLLS
0 2
ERK2 (human) LNCIINLkARNyLLS K259-ub
ERK2 (mouse) LNCIINLkARNYLLS K257-ub
ERK2 (rat) LNCIINLKARNYLLS K257
ERK2 (chicken) LNCIINLKARNYLLS K267
ERK2 (cow) LNCIINLKARNYLLS K259
Y261
INLkARNYLLSLPHK
0 1
ERK2 (human) INLkARNyLLSLPHk Y263-p
ERK2 (mouse) INLkARNYLLSLPHK Y261
ERK2 (rat) INLKARNYLLSLPHK Y261
ERK2 (chicken) INLKARNYLLSLPHK Y271
ERK2 (cow) INLKARNYLLSLPHK Y263
K268
YLLSLPHKNKVPWNR
0 1
ERK2 (human) yLLSLPHkNkVPWNR K270-ub
ERK2 (mouse) YLLSLPHKNKVPWNR K268
ERK2 (rat) YLLSLPHKNKVPWNR K268
ERK2 (chicken) YLLSLPHKNKVPWNR K278
ERK2 (cow) YLLSLPHKNKVPWNR K270
K270
LSLPHKNKVPWNRLF
0 1
ERK2 (human) LSLPHkNkVPWNRLF K272-ub
ERK2 (mouse) LSLPHKNKVPWNRLF K270
ERK2 (rat) LSLPHKNKVPWNRLF K270
ERK2 (chicken) LSLPHKNKVPWNRLF K280
ERK2 (cow) LSLPHKNKVPWNRLF K272
S282
RLFPNADSKALDLLD
0 1
ERK2 (human) RLFPNADskALDLLD S284-p
ERK2 (mouse) RLFPNADSKALDLLD S282
ERK2 (rat) RLFPNADSkALDLLD S282
ERK2 (chicken) RLFPNADPKALDLLD P292
ERK2 (cow) RLFPNADSKALDLLD S284
K283
LFPNADSKALDLLDK
0 1
ERK2 (human) LFPNADsKALDLLDk K285
ERK2 (mouse) LFPNADSKALDLLDK K283
ERK2 (rat) LFPNADSkALDLLDk K283-ac
ERK2 (chicken) LFPNADPKALDLLDK K293
ERK2 (cow) LFPNADSKALDLLDK K285
K283
LFPNADSKALDLLDK
0 3
ERK2 (human) LFPNADskALDLLDk K285-ub
ERK2 (mouse) LFPNADSKALDLLDK K283
ERK2 (rat) LFPNADSKALDLLDk K283
ERK2 (chicken) LFPNADPKALDLLDK K293
ERK2 (cow) LFPNADSKALDLLDK K285
K290
KALDLLDKMLTFNPH
0 3
ERK2 (human) kALDLLDkMLTFNPH K292-ub
ERK2 (mouse) KALDLLDKMLTFNPH K290
ERK2 (rat) kALDLLDKMLTFNPH K290
ERK2 (chicken) KALDLLDKMLTFNPH K300
ERK2 (cow) KALDLLDKMLTFNPH K292
K290
KALDLLDKMLTFNPH
0 1
ERK2 (human) kALDLLDKMLTFNPH K292
ERK2 (mouse) KALDLLDKMLTFNPH K290
ERK2 (rat) kALDLLDkMLTFNPH K290-ac
ERK2 (chicken) KALDLLDKMLTFNPH K300
ERK2 (cow) KALDLLDKMLTFNPH K292
K328
PIAEAPFKFDMELDD
0 1
ERK2 (human) PIAEAPFkFDMELDD K330-ub
ERK2 (mouse) PIAEAPFKFDMELDD K328
ERK2 (rat) PIAEAPFKFDMELDD K328
ERK2 (chicken) PVAEAPFKFDMELDD K338
ERK2 (cow) PVAEAPFKFDMELDD K330
K338
MELDDLPKEKLKELI
0 1
ERK2 (human) MELDDLPkEKLkELI K340-ub
ERK2 (mouse) MELDDLPKEKLKELI K338
ERK2 (rat) MELDDLPKEKLKELI K338
ERK2 (chicken) MELDDLPKEKLKELI K348
ERK2 (cow) MELDDLPKEKLKELI K340
K342
DLPKEKLKELIFEET
0 4
ERK2 (human) DLPkEKLkELIFEET K344-ub
ERK2 (mouse) DLPKEKLKELIFEET K342
ERK2 (rat) DLPKEKLKELIFEET K342
ERK2 (chicken) DLPKEKLKELIFEET K352
ERK2 (cow) DLPKEKLKELIFEET K344
S358-p
RFQPGYRs_______
0 4
ERK2 (human) RFQPGYRs_______ S360-p
ERK2 (mouse) RFQPGYRs_______ S358-p
ERK2 (rat) RFQPGYRS_______ S358
ERK2 (chicken) RFQPGYRS_______ S368
ERK2 (cow) RFQPGYRS_______ S360