Other Species / Isoforms
  SP1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsDQDHsMD
Upstream
0 22
Treatment
  • nocodazole
SP1 (human) ______MsDQDHsMD S2-p
SP1 (mouse) ______MsDQDHsMD S2-p
SP1 (rat) ______MsDQDHsMD S2-p
S7-p
_MsDQDHsMDEMtAV
Upstream
Downstream
1 22
Effects on Modified Protein
  • protein degradation
Treatment
  • ischemia
  • nocodazole
SP1 (human) _MsDQDHsMDEMtAV S7-p
SP1 (mouse) _MsDQDHsMDEVTAV S7-p
SP1 (rat) _MsDQDHsMDEVTAV S7-p
T12-p
DHsMDEMtAVVkIEK
0 2
SP1 (human) DHsMDEMtAVVkIEK T12-p
SP1 (mouse) DHsMDEVTAVVKIEK T12
SP1 (rat) DHsMDEVTAVkIEkG T12
K16
DEMtAVVKIEKGVGG
0 1
SP1 (human) DEMtAVVKIEKGVGG K16
SP1 (mouse) DEVTAVVKIEKDVGG K16
SP1 (rat) MDEVTAVkIEkGVGG K15-ac
K16-sm
DEMtAVVkIEKGVGG
2 2
SP1 (human) DEMtAVVkIEKGVGG K16-sm
SP1 (mouse) DEVTAVVKIEKDVGG K16
SP1 (rat) MDEVTAVKIEkGVGG K15
K19
tAVVkIEKGVGGNNG
0 1
SP1 (human) tAVVkIEKGVGGNNG K19
SP1 (mouse) TAVVKIEKDVGGNNG K19
SP1 (rat) VTAVkIEkGVGGNNG K18-ac
S36-p
GNGGGAFsQARSSsT
0 5
SP1 (human) GNGGGAFsQARSSsT S36-p
SP1 (mouse) NGGGAAFSQTRSsst S37
SP1 (rat) NGGGAAFSQTRSSST S36
S41
AFsQARSSsTGsSSS
0 1
SP1 (human) AFsQARSSsTGsSSS S41
SP1 (mouse) AFSQTRSsstGSsSs S42-p
SP1 (rat) AFSQTRSSSTGSSSS S41
S42-p
FsQARSSsTGsSSSt
Upstream
Downstream
1 1
Effects on Biological Processes:
  • transcription, induced
Putative in vivo kinases:
  • Akt1 (human)
SP1 (human) FsQARSSsTGsSSSt S42-p
SP1 (mouse) FSQTRSsstGSsSsS S43-p
SP1 (rat) FSQTRSSSTGSSSSS S42
T43
sQARSSsTGsSSStG
0 1
SP1 (human) sQARSSsTGsSSStG T43
SP1 (mouse) SQTRSsstGSsSsSG T44-p
SP1 (rat) SQTRSSSTGSSSSSG T43
S45-p
ARSSsTGsSSStGGG
0 1
SP1 (human) ARSSsTGsSSStGGG S45-p
SP1 (mouse) TRSsstGSsSsSGGG S46
SP1 (rat) TRSSSTGSSSSSGGG S45
S46
RSSsTGsSSStGGGG
0 1
SP1 (human) RSSsTGsSSStGGGG S46
SP1 (mouse) RSsstGSsSsSGGGG S47-p
SP1 (rat) RSSSTGSSSSSGGGG S46
S48
SsTGsSSStGGGGQE
0 1
SP1 (human) SsTGsSSStGGGGQE S48
SP1 (mouse) sstGSsSsSGGGGGQ S49-p
SP1 (rat) SSTGSSSSSGGGGGQ S48
T49-p
sTGsSSStGGGGQEs
0 1
SP1 (human) sTGsSSStGGGGQEs T49-p
SP1 (mouse) stGSsSsSGGGGGQE S50
SP1 (rat) STGSSSSSGGGGGQE S49
S56-p
tGGGGQEsQPsPLAL
Upstream
2 2
Putative in vivo kinases:
  • ATM (human)
Treatment
  • hydroxyurea
  • ionizing_radiation
  • UV
  • virus infection
  • Zeocin
SP1 (human) tGGGGQEsQPsPLAL S56-p
SP1 (mouse) GGGGGQEsQPsPLAL S58-p
SP1 (rat) GGGGGQESQPsPLAL S57
S59-p
GGQEsQPsPLALLAA
Upstream
Downstream
5 16
Effects on Modified Protein
  • O-GlcNAc glycosylation
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • cell motility, induced
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
  • PKCI (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • PKCA (human)
Treatment
  • seliciclib
  • U0126
SP1 (human) GGQEsQPsPLALLAA S59-p
SP1 (mouse) GGQEsQPsPLALLAA S61-p
SP1 (rat) GGQESQPsPLALLAA S60-p
S73-p
ATCSRIEsPNENSNN
0 2
SP1 (human) ATCSRIEsPNENSNN S73-p
SP1 (mouse) ATCSRIESPNENSNN S75
SP1 (rat) ATCSRIESPNENSNN S74
S101-p
DLTATQLsQGANGWQ
Upstream
Downstream
5 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, altered
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
  • ATR (human)
Treatment
  • 4-HT
  • H2O2
  • hydroxyurea
  • ionizing_radiation
  • KU-55933
  • UV
  • virus infection
  • Zeocin
SP1 (human) DLTATQLsQGANGWQ S101-p
SP1 (mouse) DLTATQLSQGANGWQ S103
SP1 (rat) DLTATQLSQGANGWQ S102
D199-ca
TGAQVQQdGSGQIQI
0 1
SP1 (human) TGAQVQQdGSGQIQI D199-ca
SP1 (mouse) TGAQVQQDGSGQIQI D201
SP1 (rat) TGAQVQQDGSGQIQI D200
T278-p
SVSAATLtPSSQAVT
Upstream
Downstream
2 0
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • JNK1 (human)
Putative in vivo kinases:
  • JNK1 (human)
Regulatory protein:
  • HSP90A (human)
Treatment
  • geldanamycin
  • nocodazole
  • SP600125
SP1 (human) SVSAATLtPSSQAVT T278-p
SP1 (mouse) SVSAATLTPSSQAGT T280
SP1 (rat) SVSAATLTPSSQAGT T279
S307
TSGTTISSASLVSSQ
0 1
SP1 (human) TSGTTISSASLVSSQ S307
SP1 (mouse) TSGTAISsASLVSSQ S309-p
SP1 (rat) TSGTAISSASLVSSQ S308
S318
VSSQASSSSFFTNAN
0 1
SP1 (human) VSSQASSSSFFTNAN S318
SP1 (mouse) VSSQASSssFFTNAN S320-p
SP1 (rat) VSSQASSSSFFTNAN S319
S319
SSQASSSSFFTNANS
0 1
SP1 (human) SSQASSSSFFTNANS S319
SP1 (mouse) SSQASSssFFTNANS S321-p
SP1 (rat) SSQASSSSFFTNANS S320
T453-p
SGPIIIRtPTVGPNG
Upstream
Downstream
6 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (human)
Phosphatases, in vitro:
  • PPP2CB (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK1 (rat)
  • ERK2 (human)
  • ERK2 (rat)
Regulatory protein:
  • TRAIL (mouse)
Treatment
  • FGF2
  • injury
  • PD98059
  • perifosine
  • SU5402
SP1 (human) SGPIIIRtPTVGPNG T453-p
SP1 (mouse) SGPIIIRTPTVGPNG T455
SP1 (rat) SGPIIIRtPTVGPNG T454-p
S491-gl
LAPMQGVsLGQTSSS
3 0
SP1 (human) LAPMQGVsLGQTSSS S491-gl
SP1 (mouse) LAPMQGVsLGQTSSS S493-gl
SP1 (rat) LAPMQGVSLGQTSSS S492
K610-ub
ACTCPYCkDsEGrGs
0 2
SP1 (human) ACTCPYCkDsEGrGs K610-ub
SP1 (mouse) ACTCPYCKDSEGRAS K611
SP1 (rat) ACTCPYCKDsEGRGS K611
S612
TCPYCkDSEGrGsGD
0 1
SP1 (human) TCPYCkDSEGrGsGD S612
SP1 (mouse) TCPYCKDSEGRASGD S613
SP1 (rat) TCPYCKDsEGRGSGD S613-p
S612-gl
TCPYCkDsEGrGsGD
2 1
SP1 (human) TCPYCkDsEGrGsGD S612-gl
SP1 (mouse) TCPYCKDSEGRASGD S613
SP1 (rat) TCPYCKDsEGRGSGD S613-gl
R615-m1
YCkDsEGrGsGDPGK
0 1
SP1 (human) YCkDsEGrGsGDPGK R615-m1
SP1 (mouse) YCKDSEGRASGDPGK R616
SP1 (rat) YCKDsEGRGSGDPGK R616
S617-p
kDsEGrGsGDPGKKk
Upstream
0 1
Treatment
  • nocodazole
SP1 (human) kDsEGrGsGDPGKKk S617-p
SP1 (mouse) KDSEGRASGDPGKKK S618
SP1 (rat) KDsEGRGSGDPGKKK S618
K624-ub
sGDPGKKkQHICHIQ
0 1
SP1 (human) sGDPGKKkQHICHIQ K624-ub
SP1 (mouse) SGDPGKKKQHICHIQ K625
SP1 (rat) SGDPGKKKQHICHIQ K625
T640
CGKVYGKTsHLRAHL
0 1
SP1 (human) CGKVYGKTsHLRAHL T640
SP1 (mouse) CGKVYGKTSHLRAHL T641
SP1 (rat) CGKVYGKtsHLRAHL T641-p
T640-gl
CGKVYGKtsHLRAHL
2 1
SP1 (human) CGKVYGKtsHLRAHL T640-gl
SP1 (mouse) CGKVYGKTSHLRAHL T641
SP1 (rat) CGKVYGKtsHLRAHL T641-gl
S641-p
GKVYGKtsHLRAHLR
Upstream
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
  • transcription, induced
Putative in vivo kinases:
  • PKCZ (human)
Treatment
  • Go_6976
  • LY294002
  • rottlerin
  • trichostatin_A
  • wortmannin
SP1 (human) GKVYGKtsHLRAHLR S641-p
SP1 (mouse) GKVYGKTSHLRAHLR S642
SP1 (rat) GKVYGKtsHLRAHLR S642-p
S641-gl
GKVYGKtsHLRAHLR
2 1
SP1 (human) GKVYGKtsHLRAHLR S641-gl
SP1 (mouse) GKVYGKTSHLRAHLR S642
SP1 (rat) GKVYGKtsHLRAHLR S642-gl
T651-p
RAHLRWHtGERPFMC
0 13
SP1 (human) RAHLRWHtGERPFMC T651-p
SP1 (mouse) RAHLRWHTGERPFMC T652
SP1 (rat) RAHLRWHTGERPFMC T652
T668-p
SYCGKRFtRsDELQR
Upstream
2 0
Kinase, in vitro:
  • PKCZ (human)
Putative in vivo kinases:
  • PKCZ (human)
Treatment
  • angiotensin_2
  • losartan
  • PD123319
SP1 (human) SYCGKRFtRsDELQR T668-p
SP1 (mouse) SYCGKRFTRSDELQR T669
SP1 (rat) SYCGKRFtRsDELQR T669-p
S670-p
CGKRFtRsDELQRHK
Upstream
1 5
Kinase, in vitro:
  • PKCZ (human)
Putative in vivo kinases:
  • PKCZ (human)
Treatment
  • angiotensin_2
  • losartan
  • PD123319
SP1 (human) CGKRFtRsDELQRHK S670-p
SP1 (mouse) CGKRFTRSDELQRHK S671
SP1 (rat) CGKRFtRsDELQRHK S671-p
T679-p
ELQRHKRtHtGEKkF
Upstream
Downstream
1 1
Effects on Biological Processes:
  • transcription, induced
Putative in vivo kinases:
  • Akt1 (human)
SP1 (human) ELQRHKRtHtGEKkF T679-p
SP1 (mouse) ELQRHKRTHTGEKKF T680
SP1 (rat) ELQRHKRTHtGEKKF T680
T681-p
QRHKRtHtGEKkFAC
Upstream
2 2
Kinase, in vitro:
  • PKCZ (human)
Putative in vivo kinases:
  • PKCZ (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Treatment
  • angiotensin_2
  • losartan
  • PD123319
SP1 (human) QRHKRtHtGEKkFAC T681-p
SP1 (mouse) QRHKRTHTGEKKFAC T682
SP1 (rat) QRHKRTHtGEKKFAC T682-p
K685-ub
RtHtGEKkFACPECP
0 1
SP1 (human) RtHtGEKkFACPECP K685-ub
SP1 (mouse) RTHTGEKKFACPECP K686
SP1 (rat) RTHtGEKKFACPECP K686
K693-ub
FACPECPkRFMRsDH
0 1
SP1 (human) FACPECPkRFMRsDH K693-ub
SP1 (mouse) FACPECPKRFMRSDH K694
SP1 (rat) FACPECPKRFMRsDH K694
S698-p
CPkRFMRsDHLskHI
Upstream
Downstream
1 1
Effects on Biological Processes:
  • transcription, induced
Putative in vivo kinases:
  • Akt1 (human)
SP1 (human) CPkRFMRsDHLskHI S698-p
SP1 (mouse) CPKRFMRSDHLSKHI S699
SP1 (rat) CPKRFMRsDHLsKHI S699-p
S698-gl
CPkRFMRsDHLskHI
2 1
SP1 (human) CPkRFMRsDHLskHI S698-gl
SP1 (mouse) CPKRFMRSDHLSKHI S699
SP1 (rat) CPKRFMRsDHLsKHI S699-gl
S702-p
FMRsDHLskHIKtHQ
Downstream
2 2
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
SP1 (human) FMRsDHLskHIKtHQ S702-p
SP1 (mouse) FMRSDHLSKHIKTHQ S703
SP1 (rat) FMRsDHLsKHIKTHQ S703-p
S702-gl
FMRsDHLskHIKtHQ
2 1
SP1 (human) FMRsDHLskHIKtHQ S702-gl
SP1 (mouse) FMRSDHLSKHIKTHQ S703
SP1 (rat) FMRsDHLsKHIKTHQ S703-gl
K703-ac
MRsDHLskHIKtHQN
1 0
SP1 (human) MRsDHLskHIKtHQN K703-ac
SP1 (mouse) MRSDHLSKHIKTHQN K704
SP1 (rat) MRsDHLsKHIKTHQN K704
T707-p
HLskHIKtHQNKKGG
0 1
SP1 (human) HLskHIKtHQNKKGG T707-p
SP1 (mouse) HLSKHIKTHQNKKGG T708
SP1 (rat) HLsKHIKTHQNKKGG T708
S720-p
GGPGVALsVGtLPLD
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Regulatory protein:
  • PIN1 (human)
SP1 (human) GGPGVALsVGtLPLD S720-p
SP1 (mouse) GGPGVALSVGTLPLD S721
SP1 (rat) GGPGVALSVGTLPLD S721
T723-p
GVALsVGtLPLDsGA
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Regulatory protein:
  • PIN1 (human)
SP1 (human) GVALsVGtLPLDsGA T723-p
SP1 (mouse) GVALSVGTLPLDSGA T724
SP1 (rat) GVALSVGTLPLDSGA T724
S728-p
VGtLPLDsGAGsEGS
Downstream
2 0
Effects on Modified Protein
  • protein degradation
SP1 (human) VGtLPLDsGAGsEGS S728-p
SP1 (mouse) VGTLPLDSGAGSEGT S729
SP1 (rat) VGTLPLDSGAGSEGS S729
S732-p
PLDsGAGsEGSGtAt
Downstream
2 0
Effects on Modified Protein
  • protein degradation
SP1 (human) PLDsGAGsEGSGtAt S732-p
SP1 (mouse) PLDSGAGSEGTATPS S733
SP1 (rat) PLDSGAGSEGSGTAt S733
T737-p
AGsEGSGtAtPSALI
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Regulatory protein:
  • PIN1 (human)
SP1 (human) AGsEGSGtAtPSALI T737-p
SP1 (mouse) SGAGSEGTATPSALI T736
SP1 (rat) AGSEGSGTAtPSALI T738
T739-p
sEGSGtAtPSALITT
Upstream
Downstream
14 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CDK1 (human)
  • ERK1 (human)
  • ERK2 (human)
  • JNK1 (human)
Phosphatases, in vitro:
  • PPP2CA (human)
  • PPP2CB (human)
Putative in vivo kinases:
  • CDK1 (human)
  • ERK1 (human)
  • ERK1 (rat)
  • ERK2 (human)
  • ERK2 (rat)
  • JNK1 (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • HSP90A (human)
Treatment
  • estradiol
  • FGF2
  • geldanamycin
  • nocodazole
  • PD98059
  • perifosine
  • serum
  • SP600125
SP1 (human) sEGSGtAtPSALITT T739-p
SP1 (mouse) AGSEGTATPSALITT T738
SP1 (rat) SEGSGTAtPSALITT T740-p