Other Species / Isoforms
  Huntingtin (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T3-p
_____MAtLEkLMkA
Upstream
Downstream
13 4
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein stabilization
Kinase, in vitro:
  • GCK (human)
  • HGK (human)
  • TNIK (human)
view more >
Putative in vivo kinases:
  • GCK (human)
  • HGK (human)
  • IKKB (human)
  • TNIK (human)
view more >
Huntingtin (human) _____MAtLEkLMkA T3-p
Huntingtin (mouse) _____MAtLEkLMkA T3-p
Huntingtin (rat) gap -
K6-ac
__MAtLEkLMkAFEs
Downstream
2 1
Effects on Modified Protein
  • protein conformation
  • protein stabilization
Huntingtin (human) __MAtLEkLMkAFEs K6-ac
Huntingtin (mouse) __MAtLEKLMkAFEs K6
Huntingtin (rat) gap -
K6-ub
__MAtLEkLMkAFEs
Downstream
1 0
Effects on Modified Protein
  • ubiquitination
Huntingtin (human) __MAtLEkLMkAFEs K6-ub
Huntingtin (mouse) __MAtLEKLMkAFEs K6
Huntingtin (rat) gap -
K6-sm
__MAtLEkLMkAFEs
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • transcription, inhibited
Huntingtin (human) __MAtLEkLMkAFEs K6-sm
Huntingtin (mouse) __MAtLEkLMkAFEs K6-sm
Huntingtin (rat) gap -
K9-ac
AtLEkLMkAFEsLks
2 1
Huntingtin (human) AtLEkLMkAFEsLks K9-ac
Huntingtin (mouse) AtLEkLMkAFEsLks K9-ac
Huntingtin (rat) ______MKAFESLKS K2
K9-ub
AtLEkLMkAFEsLks
Downstream
1 0
Effects on Modified Protein
  • ubiquitination
Huntingtin (human) AtLEkLMkAFEsLks K9-ub
Huntingtin (mouse) AtLEkLMKAFEsLks K9
Huntingtin (rat) ______MKAFESLKS K2
K9-sm
AtLEkLMkAFEsLks
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • transcription, inhibited
Huntingtin (human) AtLEkLMkAFEsLks K9-sm
Huntingtin (mouse) AtLEkLMkAFEsLks K9-sm
Huntingtin (rat) ______MKAFESLKS K2
S13-p
kLMkAFEsLksFQQQ
Upstream
Downstream
19 3
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • receptor internalization, induced
Effects on Biological Processes:
  • apoptosis, inhibited
  • cytoskeletal reorganization
  • exocytosis, inhibited
Kinase, in vitro:
  • HGK (human)
  • IKKB (human)
  • TBK1 (human)
  • TNIK (human)
view more >
Putative in vivo kinases:
  • CK2A1 (human)
  • HGK (human)
  • IKKB (human)
  • IKKE (human)
  • TBK1 (human)
  • TNIK (human)
view more >
Regulatory protein:
  • PPP2CA (human)
Treatment
  • Bay_11-7082
  • heat_shock
  • IC261
  • LY294002
  • okadaic_acid
  • piceatannol
  • Ro31-8220
  • siRNA
  • staurosporine
  • wortmannin
  • Y27632
view more >
Huntingtin (human) kLMkAFEsLksFQQQ S13-p
Huntingtin (mouse) kLMkAFEsLksFQQQ S13-p
Huntingtin (rat) __MKAFESLKSFQQQ S6
K15-ac
MkAFEsLksFQQQQQ
1 0
Huntingtin (human) MkAFEsLksFQQQQQ K15-ac
Huntingtin (mouse) MkAFEsLKsFQQQQQ K15
Huntingtin (rat) MKAFESLKSFQQQQQ K8
K15-sm
MkAFEsLksFQQQQQ
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • transcription, inhibited
Huntingtin (human) MkAFEsLksFQQQQQ K15-sm
Huntingtin (mouse) MkAFEsLksFQQQQQ K15-sm
Huntingtin (rat) MKAFESLKSFQQQQQ K8
S16-p
kAFEsLksFQQQQQQ
Upstream
Downstream
18 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • receptor internalization, induced
Effects on Biological Processes:
  • apoptosis, inhibited
  • cytoskeletal reorganization
Kinase, in vitro:
  • IKKB (human)
  • TBK1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
  • IKKB (human)
  • TBK1 (human)
view more >
Treatment
  • Bay_11-7082
  • heat_shock
  • IC261
  • LY294002
  • piceatannol
  • Ro31-8220
  • staurosporine
  • wortmannin
  • Y27632
view more >
Huntingtin (human) kAFEsLksFQQQQQQ S16-p
Huntingtin (mouse) kAFEsLksFQQQQQQ S16-p
Huntingtin (rat) KAFESLKSFQQQQQQ S9
K96-ac
KKELSATkKDRVNHC
0 1
Huntingtin (human) KKELSATkKDRVNHC K96-ac
Huntingtin (mouse) KKELSATKKDRVNHC K75
Huntingtin (rat) KKELSATKKDRVNHC K67
S114-p
CENIVAQsVrNsPEF
Downstream
1 2
Effects on Biological Processes:
  • apoptosis, induced
Huntingtin (human) CENIVAQsVrNsPEF S114-p
Huntingtin (mouse) CENIVAQSLrNSPEF S93
Huntingtin (rat) CENIVAQSLRNSPEF S85
R116-m2
NIVAQsVrNsPEFQK
1 1
Huntingtin (human) NIVAQsVrNsPEFQK R116-m2
Huntingtin (mouse) NIVAQSLrNSPEFQK R95-m2
Huntingtin (rat) NIVAQSLRNSPEFQK R87
S118-p
VAQsVrNsPEFQKLL
1 1
Huntingtin (human) VAQsVrNsPEFQKLL S118-p
Huntingtin (mouse) VAQSLrNSPEFQKLL S97
Huntingtin (rat) VAQSLRNSPEFQKLL S89
S141
LCSDDAESDVRMVAD
1 0
Huntingtin (human) LCSDDAESDVRMVAD S141
Huntingtin (mouse) LCSNDAEsDVRMVAD S120-p
Huntingtin (rat) CSDDASRRRMVADEC R113
K176-ac
ELYKEIKkNGAPRSL
Upstream
1 1
Treatment
  • NaB
  • nicotinamide
  • trichostatin_A
view more >
Huntingtin (human) ELYKEIKkNGAPRSL K176-ac
Huntingtin (mouse) ELYKEIKKNGAPRSL K155
Huntingtin (rat) ELYKEIKKNGAPRSL K146
K234-ac
TLAAAVPkIMASFGN
1 1
Huntingtin (human) TLAAAVPkIMASFGN K234-ac
Huntingtin (mouse) TLAAAVPKIMASFGN K213
Huntingtin (rat) TLAAAVPKIMASFGN K204
K253-ub
NEIKVLLkAFIANLK
0 1
Huntingtin (human) NEIKVLLkAFIANLK K253-ub
Huntingtin (mouse) NEIKVLLKAFIANLK K232
Huntingtin (rat) NEIKVLLKAFIANLK K223
T265
NLKSSSPTIRRtAAG
0 1
Huntingtin (human) NLKSSSPTIRRtAAG T265
Huntingtin (mouse) NLKSSSPtVRRTAAG T244-p
Huntingtin (rat) NLKSSSPTVRRTAAG T235
T269-p
SSPTIRRtAAGSAVs
1 1
Huntingtin (human) SSPTIRRtAAGSAVs T269-p
Huntingtin (mouse) SSPtVRRTAAGSAVS T248
Huntingtin (rat) SSPTVRRTAAGSAVS T239
S276-p
tAAGSAVsICQHSRR
0 1
Huntingtin (human) tAAGSAVsICQHSRR S276-p
Huntingtin (mouse) TAAGSAVSICQHSRR S255
Huntingtin (rat) TAAGSAVSICQHSRR S246
K335-ub
QVKDTSLkGsFGVTR
0 1
Huntingtin (human) QVKDTSLkGsFGVTR K335-ub
Huntingtin (mouse) QVKDTSLKGSFGVTR K314
Huntingtin (rat) QVKDTSLKGSFGVTR K305
S337-p
KDTSLkGsFGVTRkE
0 1
Huntingtin (human) KDTSLkGsFGVTRkE S337-p
Huntingtin (mouse) KDTSLKGSFGVTRKE S316
Huntingtin (rat) KDTSLKGSFGVTRKE S307
K343-ac
GsFGVTRkEMEVSPS
1 1
Huntingtin (human) GsFGVTRkEMEVSPS K343-ac
Huntingtin (mouse) GSFGVTRKEMEVSPS K322
Huntingtin (rat) GSFGVTRKEMEVSPS K313
T405-p
VGGIGQLtAAKEEsG
0 2
Huntingtin (human) VGGIGQLtAAKEEsG T405-p
Huntingtin (mouse) PGGLGQLTLVQEEAR T384
Huntingtin (rat) PGGLGQLTLVREEAG T375
S411-p
LtAAKEEsGGRsRsG
0 3
Huntingtin (human) LtAAKEEsGGRsRsG S411-p
Huntingtin (mouse) LTLVQEEARGRGRsG A390
Huntingtin (rat) LTLVREEAGGRGRsG A381
S415-p
KEEsGGRsRsGsIVE
1 6
Huntingtin (human) KEEsGGRsRsGsIVE S415-p
Huntingtin (mouse) QEEARGRGRsGsIVE G394
Huntingtin (rat) REEAGGRGRsGsIVE G385
S417-p
EsGGRsRsGsIVELI
1 17
Huntingtin (human) EsGGRsRsGsIVELI S417-p
Huntingtin (mouse) EARGRGRsGsIVELL S396-p
Huntingtin (rat) EAGGRGRsGsIVELL S387-p
S419-p
GGRsRsGsIVELIAG
Upstream
Downstream
14 52
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • apoptosis, inhibited
  • cytoskeletal reorganization
  • signaling pathway regulation
Kinase, in vitro:
  • Akt1 (human)
  • SGK1 (human)
Phosphatases, in vitro:
  • PPM1B (human)
  • PPP2CA (human)
  • PPP3CA (human)
  • PPPM1A (human)
view more >
Putative in vivo kinases:
  • Akt1 (human)
  • SGK1 (human)
Putative upstream phosphatases:
  • PPM1B (human)
  • PPP3CA (human)
  • PPPM1A (human)
view more >
Regulatory protein:
  • 5-HT(2C) (human)
  • ADRA2A (human)
  • ADRB2 (human)
  • Akt1 (human)
  • ARRB2 (human)
  • CNR1 (human)
  • DRD1 (human)
  • DRD2 (human)
  • DRD4 (human)
  • DRD5 (human)
  • PPP3CA (human)
view more >
Treatment
  • 127153
  • 5-HT
  • 6-OHDA
  • apomorphine
  • bromocriptine
  • cadmium_chloride
  • ciclosporin
  • cypermethrin
  • EGF
  • exenatide
  • FK506
  • haloperidol
  • IGF-1
  • insulin
  • ionomycin
  • isoproterenol
  • LY294002
  • norepinephrine
  • NPA
  • okadaic_acid
  • PTX
  • raclopride
  • siRNA
  • U0126
  • WIN
view more >
Huntingtin (human) GGRsRsGsIVELIAG S419-p
Huntingtin (mouse) RGRGRsGsIVELLAG S398-p
Huntingtin (rat) GGRGRsGsIVELLAG S389-p
S429-p
ELIAGGGssCsPVLs
Downstream
2 10
Effects on Modified Protein
  • protein degradation
Huntingtin (human) ELIAGGGssCsPVLs S429-p
Huntingtin (mouse) ELLAGGGSsCsPVLs S408
Huntingtin (rat) ELLAGGGSSCsPVLS S399
S430-p
LIAGGGssCsPVLsR
Downstream
1 9
Effects on Modified Protein
  • protein stabilization
Huntingtin (human) LIAGGGssCsPVLsR S430-p
Huntingtin (mouse) LLAGGGSsCsPVLsR S409-p
Huntingtin (rat) LLAGGGSSCsPVLSR S400
S432-p
AGGGssCsPVLsRKQ
Upstream
3 109
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • seliciclib
Huntingtin (human) AGGGssCsPVLsRKQ S432-p
Huntingtin (mouse) AGGGSsCsPVLsRKQ S411-p
Huntingtin (rat) AGGGSSCsPVLSRKQ S402-p
S436-p
ssCsPVLsRKQKGkV
0 9
Huntingtin (human) ssCsPVLsRKQKGkV S436-p
Huntingtin (mouse) SsCsPVLsRKQKGkV S415-p
Huntingtin (rat) SSCsPVLSRKQKGKV S406
K442-ac
LsRKQKGkVLLGEEE
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • autophagy, induced
Regulatory protein:
  • HAT1 (human)
  • MYST2 (human)
  • p300 (human)
  • PCAF (human)
  • Tip60 (human)
view more >
Treatment
  • nicotinamide
  • siRNA
  • trichostatin_A
view more >
Huntingtin (human) LsRKQKGkVLLGEEE K442-ac
Huntingtin (mouse) LsRKQKGkVLLGEEE K421-ac
Huntingtin (rat) LSRKQKGKVLLGEEE K412
K442-ub
LsRKQKGkVLLGEEE
1 1
Huntingtin (human) LsRKQKGkVLLGEEE K442-ub
Huntingtin (mouse) LsRKQKGKVLLGEEE K421
Huntingtin (rat) LSRKQKGKVLLGEEE K412
S455-p
EEALEDDsEsRsDVs
1 1
Huntingtin (human) EEALEDDsEsRsDVs S455-p
Huntingtin (mouse) EEALEDDSESRSDVS S434
Huntingtin (rat) EEALEDDSESRSDVS S425
S457-p
ALEDDsEsRsDVsss
1 1
Huntingtin (human) ALEDDsEsRsDVsss S457-p
Huntingtin (mouse) ALEDDSESRSDVSSS S436
Huntingtin (rat) ALEDDSESRSDVSSS S427
S459-p
EDDsEsRsDVsssAL
1 1
Huntingtin (human) EDDsEsRsDVsssAL S459-p
Huntingtin (mouse) EDDSESRSDVSSSAF S438
Huntingtin (rat) EDDSESRSDVSSSAF S429
S462-p
sEsRsDVsssALTAS
1 1
Huntingtin (human) sEsRsDVsssALTAS S462-p
Huntingtin (mouse) SESRSDVSSSAFAAS S441
Huntingtin (rat) SESRSDVSSSAFAAS S432
S463-p
EsRsDVsssALTASV
1 1
Huntingtin (human) EsRsDVsssALTASV S463-p
Huntingtin (mouse) ESRSDVSSSAFAASV S442
Huntingtin (rat) ESRSDVSSSAFAASV S433
S464-p
sRsDVsssALTASVK
1 1
Huntingtin (human) sRsDVsssALTASVK S464-p
Huntingtin (mouse) SRSDVSSSAFAASVK S443
Huntingtin (rat) SRSDVSSSAFAASVK S434
S485-p
LAASSGVstPGsAGH
1 1
Huntingtin (human) LAASSGVstPGsAGH S485-p
Huntingtin (mouse) LAASSGVSTPGSVGH S464
Huntingtin (rat) AASSSGVSTPGSVGH S456
T486-p
AASSGVstPGsAGHD
1 2
Huntingtin (human) AASSGVstPGsAGHD T486-p
Huntingtin (mouse) AASSGVSTPGSVGHD T465
Huntingtin (rat) ASSSGVSTPGSVGHD T457
S489-p
SGVstPGsAGHDIIT
1 1
Huntingtin (human) SGVstPGsAGHDIIT S489-p
Huntingtin (mouse) SGVSTPGSVGHDIIT S468
Huntingtin (rat) SGVSTPGSVGHDIIT S460
S534-p
EDILSHSsSQVSAVP
Downstream
0 1
Effects on Modified Protein
  • protein stabilization
Huntingtin (human) EDILSHSsSQVSAVP S534-p
Huntingtin (mouse) EDILSHSSSQFSAVP S513
Huntingtin (rat) EDILSHSSSQFSAVP S505
S620-p
ASEAFRNsSMALQQA
0 1
Huntingtin (human) ASEAFRNsSMALQQA S620-p
Huntingtin (mouse) VSDVFRNSsLALQQA S600
Huntingtin (rat) VSDVFRNSSLALQQA S591
S621
SEAFRNsSMALQQAH
0 1
Huntingtin (human) SEAFRNsSMALQQAH S621
Huntingtin (mouse) SDVFRNSsLALQQAH S601-p
Huntingtin (rat) SDVFRNSSLALQQAH S592
C636
LLKNMSHCRQPsDss
0 1
Huntingtin (human) LLKNMSHCRQPsDss C636
Huntingtin (mouse) LLERMGHsRQPsDSs S616-p
Huntingtin (rat) LLERMGHSRQPSDSS S607
S640-p
MSHCRQPsDssVDKF
0 26
Huntingtin (human) MSHCRQPsDssVDKF S640-p
Huntingtin (mouse) MGHsRQPsDSsIDKY S620-p
Huntingtin (rat) MGHSRQPSDSSVDKF S611
S642-p
HCRQPsDssVDKFVL
0 1
Huntingtin (human) HCRQPsDssVDKFVL S642-p
Huntingtin (mouse) HsRQPsDSsIDKYVT S622
Huntingtin (rat) HSRQPSDSSVDKFVS S613
S643-p
CRQPsDssVDKFVLR
0 6
Huntingtin (human) CRQPsDssVDKFVLR S643-p
Huntingtin (mouse) sRQPsDSsIDKYVTR S623-p
Huntingtin (rat) SRQPSDSSVDKFVSK S614
T654-p
FVLRDEAtEPGDQEN
0 1
Huntingtin (human) FVLRDEAtEPGDQEN T654-p
Huntingtin (mouse) YVTRDEVAEAsDPES A634
Huntingtin (rat) FVSKDEVAEAGDPES A625
G657
RDEAtEPGDQENkPC
0 5
Huntingtin (human) RDEAtEPGDQENkPC G657
Huntingtin (mouse) RDEVAEAsDPESKPC S637-p
Huntingtin (rat) KDEVAEAGDPESKPC G628
K662-ub
EPGDQENkPCRIkGD
0 1
Huntingtin (human) EPGDQENkPCRIkGD K662-ub
Huntingtin (mouse) EAsDPESKPCRIKGD K642
Huntingtin (rat) EAGDPESKPCRIKGD K633
K667-ub
ENkPCRIkGDIGQST
0 1
Huntingtin (human) ENkPCRIkGDIGQST K667-ub
Huntingtin (mouse) ESKPCRIKGDIGQPN K647
Huntingtin (rat) ESKPCRIKGDIGQPN K638
K698-ub
SFLLTGGkNVLVPDR
0 1
Huntingtin (human) SFLLTGGkNVLVPDR K698-ub
Huntingtin (mouse) SFLLTGEKKALVPDR K678
Huntingtin (rat) SFLLTGEKKALVPDR K669
T796-p
DWMGTIRtLTGNTFS
0 1
Huntingtin (human) DWMGTIRtLTGNTFS T796-p
Huntingtin (mouse) DWLGNIRTLTGNTFS T776
Huntingtin (rat) DWLGTIRALTGNTFS A767
K813-ub
DCIPLLRkTLKDESS
0 2
Huntingtin (human) DCIPLLRkTLKDESS K813-ub
Huntingtin (mouse) DCIPLLQkTLKDESS K793-ub
Huntingtin (rat) DCIPLLQKTLKDESS K784
K824-ac
DESSVTCkLACTAVR
1 1
Huntingtin (human) DESSVTCkLACTAVR K824-ac
Huntingtin (mouse) DESSVTCKLACTAVR K804
Huntingtin (rat) DESSVTCKLACTAVR K795
K902-ub
HHYTGLLkLQERVLN
0 1
Huntingtin (human) HHYTGLLkLQERVLN K902-ub
Huntingtin (mouse) HHYTGFLKLQERVLN K882
Huntingtin (rat) HHYTGFLKLQERVLN K873
S930-p
VRHVAAAsLIRLVPk
0 1
Huntingtin (human) VRHVAAAsLIRLVPk S930-p
Huntingtin (mouse) VRHVAATSLTRLVPK S910
Huntingtin (rat) VRHVAATTLTRLVPK T901
K937-ub
sLIRLVPkLFYkCDQ
0 1
Huntingtin (human) sLIRLVPkLFYkCDQ K937-ub
Huntingtin (mouse) SLTRLVPKLFYkCDQ K917
Huntingtin (rat) TLTRLVPKLFYKCDQ K908
K941-ub
LVPkLFYkCDQGQAD
0 4
Huntingtin (human) LVPkLFYkCDQGQAD K941-ub
Huntingtin (mouse) LVPKLFYkCDQGQAD K921-ub
Huntingtin (rat) LVPKLFYKCDQGQAD K912
S1055
GVPPLSASDESRKSC
0 1
Huntingtin (human) GVPPLSASDESRKSC S1055
Huntingtin (mouse) GVPPLSAsDEsRKSC S1035-p
Huntingtin (rat) GVPPLSASDESRKSC S1026
S1058
PLSASDESRKSCTVG
0 1
Huntingtin (human) PLSASDESRKSCTVG S1058
Huntingtin (mouse) PLSAsDEsRKSCTVG S1038-p
Huntingtin (rat) PLSASDESRKSCTVG S1029
S1104-p
LAASAPKsLRSSWAs
0 1
Huntingtin (human) LAASAPKsLRSSWAs S1104-p
Huntingtin (mouse) LAASAPKSLRSSWTS S1084
Huntingtin (rat) LAASAPKSLRSSWAS S1075
S1111-p
sLRSSWAsEEEANPA
0 1
Huntingtin (human) sLRSSWAsEEEANPA S1111-p
Huntingtin (mouse) SLRSSWTSEEEANSA S1091
Huntingtin (rat) SLRSSWASEEEGSSA S1082
T1120-p
EEANPAAtkQEEVWP
0 1
Huntingtin (human) EEANPAAtkQEEVWP T1120-p
Huntingtin (mouse) EEANSAATRQEEIWP T1100
Huntingtin (rat) EEGSSAATRQEEIWP T1091
K1121-ub
EANPAAtkQEEVWPA
0 1
Huntingtin (human) EANPAAtkQEEVWPA K1121-ub
Huntingtin (mouse) EANSAATRQEEIWPA R1101
Huntingtin (rat) EGSSAATRQEEIWPA R1092
T1173-p
KAALPSLtNPPsLsP
0 1
Huntingtin (human) KAALPSLtNPPsLsP T1173-p
Huntingtin (mouse) KAALPSLTNPPSLsP T1153
Huntingtin (rat) KAALPSLTNPPSLsP T1144
S1177-p
PSLtNPPsLsPIRRK
0 3
Huntingtin (human) PSLtNPPsLsPIRRK S1177-p
Huntingtin (mouse) PSLTNPPSLsPIRRK S1157
Huntingtin (rat) PSLTNPPSLsPIRRK S1148
S1179-p
LtNPPsLsPIRRKGK
Upstream
4 28
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • seliciclib
  • siRNA
Huntingtin (human) LtNPPsLsPIRRKGK S1179-p
Huntingtin (mouse) LTNPPSLsPIRRKGK S1159-p
Huntingtin (rat) LTNPPSLsPIRRKGK S1150-p
S1195-p
KEPGEQAsVPLsPKK
0 3
Huntingtin (human) KEPGEQAsVPLsPKK S1195-p
Huntingtin (mouse) KEPGEQASTPMsPKK S1175
Huntingtin (rat) KEPGEQTSTPMsPKK S1166
S1199-p
EQAsVPLsPKKGSEA
Upstream
4 30
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • ischemia
  • LRRK2-IN-1
  • seliciclib
  • siRNA
view more >
Huntingtin (human) EQAsVPLsPKKGSEA S1199-p
Huntingtin (mouse) EQASTPMsPKKVGEA S1179-p
Huntingtin (rat) EQTSTPMsPKKGGEA S1170-p
S1210-p
GSEASAAsRQSDtSG
0 1
Huntingtin (human) GSEASAAsRQSDtSG S1210-p
Huntingtin (mouse) VGEASAASRQSDTSG S1190
Huntingtin (rat) GGEASTASRQSDTSG S1181
T1215-p
AAsRQSDtSGPVTTS
0 1
Huntingtin (human) AAsRQSDtSGPVTTS T1215-p
Huntingtin (mouse) AASRQSDTSGPVTAS T1195
Huntingtin (rat) TASRQSDTSGPVTAS T1186
K1223-ub
SGPVTTSkSSSLGsF
0 1
Huntingtin (human) SGPVTTSkSSSLGsF K1223-ub
Huntingtin (mouse) SGPVTASKSSSLGSF K1203
Huntingtin (rat) SGPVTASKSSSLGSF K1194
S1229-p
SkSSSLGsFYHLPSY
0 1
Huntingtin (human) SkSSSLGsFYHLPSY S1229-p
Huntingtin (mouse) SKSSSLGSFYHLPSY S1209
Huntingtin (rat) SKSSSLGSFYHLPSY S1200
K1238
YHLPSYLKLHDVLkA
0 1
Huntingtin (human) YHLPSYLKLHDVLkA K1238
Huntingtin (mouse) YHLPSYLkLHDVLKA K1218-ub
Huntingtin (rat) YHLPSYLRLHDVLKA R1209
K1244-ub
LKLHDVLkATHANYK
0 1
Huntingtin (human) LKLHDVLkATHANYK K1244-ub
Huntingtin (mouse) LkLHDVLKATHANYK K1224
Huntingtin (rat) LRLHDVLKATHANYK K1215
K1262-ub
DLQNSTEkFGGFLRS
Upstream
0 2
Treatment
  • MG132
Huntingtin (human) DLQNSTEkFGGFLRS K1262-ub
Huntingtin (mouse) DLQNSTEkFGGFLRS K1242-ub
Huntingtin (rat) DLQNSTEKFGGFLRS K1233
T1282-p
SQILELAtLQDIGKC
0 1
Huntingtin (human) SQILELAtLQDIGKC T1282-p
Huntingtin (mouse) SQILELATLQDIGKC T1262
Huntingtin (rat) SQILELATLQDIGKC T1253
T1322-p
LLKTLFGtNLASQFD
0 1
Huntingtin (human) LLKTLFGtNLASQFD T1322-p
Huntingtin (mouse) LLKTLFGTNLASQFD T1302
Huntingtin (rat) LLKTLFGTNLASQFD T1293
K1337-ub
GLSSNPSkSQGRAQR
0 2
Huntingtin (human) GLSSNPSkSQGRAQR K1337-ub
Huntingtin (mouse) GLSSNPSkSQCRAQR K1317-ub
Huntingtin (rat) GLSSNPSKSQCRAQR K1308
S1348-p
RAQRLGSssVRPGLy
0 1
Huntingtin (human) RAQRLGSssVRPGLy S1348-p
Huntingtin (mouse) RAQRLGSSSVRPGLY S1328
Huntingtin (rat) RAQRLGSSSVRPGLY S1319
S1349-p
AQRLGSssVRPGLyH
0 1
Huntingtin (human) AQRLGSssVRPGLyH S1349-p
Huntingtin (mouse) AQRLGSSSVRPGLYH S1329
Huntingtin (rat) AQRLGSSSVRPGLYH S1320
Y1355-p
ssVRPGLyHYCFMAP
0 1
Huntingtin (human) ssVRPGLyHYCFMAP Y1355-p
Huntingtin (mouse) SSVRPGLYHYCFMAP Y1335
Huntingtin (rat) SSVRPGLYHYCFMAP Y1326
K1402-ub
QKVSTQLkTNLTSVT
Upstream
0 5
Treatment
  • MG132
Huntingtin (human) QKVSTQLkTNLTSVT K1402-ub
Huntingtin (mouse) QKVSAQLKtNLtsVt K1382
Huntingtin (rat) QKVSAQLKTNLTSVT K1373
T1403
KVSTQLkTNLTSVTk
0 1
Huntingtin (human) KVSTQLkTNLTSVTk T1403
Huntingtin (mouse) KVSAQLKtNLtsVtk T1383-p
Huntingtin (rat) KVSAQLKTNLTSVTK T1374
T1406
TQLkTNLTSVTkNRA
0 1
Huntingtin (human) TQLkTNLTSVTkNRA T1406
Huntingtin (mouse) AQLKtNLtsVtkNRA T1386-p
Huntingtin (rat) AQLKTNLTSVTKNRA T1377
S1407
QLkTNLTSVTkNRAD
0 1
Huntingtin (human) QLkTNLTSVTkNRAD S1407
Huntingtin (mouse) QLKtNLtsVtkNRAD S1387-p
Huntingtin (rat) QLKTNLTSVTKNRAD S1378
T1409
kTNLTSVTkNRADkN
0 1
Huntingtin (human) kTNLTSVTkNRADkN T1409
Huntingtin (mouse) KtNLtsVtkNRADKN T1389-p
Huntingtin (rat) KTNLTSVTKNRADKN T1380
K1410-ub
TNLTSVTkNRADkNA
0 4
Huntingtin (human) TNLTSVTkNRADkNA K1410-ub
Huntingtin (mouse) tNLtsVtkNRADKNA K1390-ub
Huntingtin (rat) TNLTSVTKNRADKNA K1381
K1415-ub
VTkNRADkNAIHNHI
0 1
Huntingtin (human) VTkNRADkNAIHNHI K1415-ub
Huntingtin (mouse) VtkNRADKNAIHNHI K1395
Huntingtin (rat) VTKNRADKNAIHNHI K1386
K1431-ub
LFEPLVIkALKQYTT
0 4
Huntingtin (human) LFEPLVIkALKQYTT K1431-ub
Huntingtin (mouse) LFEPLVIkALKQYTT K1411-ub
Huntingtin (rat) LFEPLVIKALKQYTT K1402
S1627
KQQMHIDSHEALGVL
0 1
Huntingtin (human) KQQMHIDSHEALGVL S1627
Huntingtin (mouse) KQQMHIDsHEALGVL S1607-p
Huntingtin (rat) KQQMHIDSHEALGVL S1598
K1730
LEEHSEGKQIKNLPE
0 1
Huntingtin (human) LEEHSEGKQIKNLPE K1730
Huntingtin (mouse) LGECSEGkQKSLPED K1710-ub
Huntingtin (rat) LGERSRGKQVKNLPE K1701
R1801
RITAAATRLFRsDGC
0 1
Huntingtin (human) RITAAATRLFRsDGC R1801
Huntingtin (mouse) RITAAATrLFTSDGC R1780-m2
Huntingtin (rat) RITAAATRLFTSDGC R1772
S1805-p
AATRLFRsDGCGGsF
0 1
Huntingtin (human) AATRLFRsDGCGGsF S1805-p
Huntingtin (mouse) AATrLFTSDGCEGSF S1784
Huntingtin (rat) AATRLFTSDGCEGSF S1776
S1811-p
RsDGCGGsFytLDSL
0 1
Huntingtin (human) RsDGCGGsFytLDSL S1811-p
Huntingtin (mouse) TSDGCEGSFYTLESL S1790
Huntingtin (rat) TSDGCEGSFYTLDSL S1782
Y1813-p
DGCGGsFytLDSLNL
0 1
Huntingtin (human) DGCGGsFytLDSLNL Y1813-p
Huntingtin (mouse) DGCEGSFYTLESLNA Y1792
Huntingtin (rat) DGCEGSFYTLDSLNA Y1784
T1814-p
GCGGsFytLDSLNLR
0 1
Huntingtin (human) GCGGsFytLDSLNLR T1814-p
Huntingtin (mouse) GCEGSFYTLESLNAR T1793
Huntingtin (rat) GCEGSFYTLDSLNAR T1785
T1857
WWAEVQQTPKRHsLs
0 1
Huntingtin (human) WWAEVQQTPKRHsLs T1857
Huntingtin (mouse) WWAEVQQtPKRHsLs T1836-p
Huntingtin (rat) WWAEVQQTPKRHSLS T1828
S1862-p
QQTPKRHsLsstKLL
Upstream
1 13
Treatment
  • ischemia
Huntingtin (human) QQTPKRHsLsstKLL S1862-p
Huntingtin (mouse) QQtPKRHsLsCTKSL S1841-p
Huntingtin (rat) QQTPKRHSLSCTKSL S1833
S1864-p
TPKRHsLsstKLLsP
1 10
Huntingtin (human) TPKRHsLsstKLLsP S1864-p
Huntingtin (mouse) tPKRHsLsCTKSLNP S1843-p
Huntingtin (rat) TPKRHSLSCTKSLNP S1835
S1865-p
PKRHsLsstKLLsPQ
1 1
Huntingtin (human) PKRHsLsstKLLsPQ S1865-p
Huntingtin (mouse) PKRHsLsCTKSLNPQ C1844
Huntingtin (rat) PKRHSLSCTKSLNPQ C1836
T1866-p
KRHsLsstKLLsPQM
0 1
Huntingtin (human) KRHsLsstKLLsPQM T1866-p
Huntingtin (mouse) KRHsLsCTKSLNPQK T1845
Huntingtin (rat) KRHSLSCTKSLNPQI T1837
S1870-p
LsstKLLsPQMsGEE
1 14
Huntingtin (human) LsstKLLsPQMsGEE S1870-p
Huntingtin (mouse) LsCTKSLNPQKsGEE N1849
Huntingtin (rat) LSCTKSLNPQISAEE N1841
S1874-p
KLLsPQMsGEEEDsD
Upstream
1 39
Treatment
  • ischemia
Huntingtin (human) KLLsPQMsGEEEDsD S1874-p
Huntingtin (mouse) KSLNPQKsGEEEDSG S1853-p
Huntingtin (rat) KSLNPQISAEEDSGS S1845
S1880-p
MsGEEEDsDLAAkLG
0 1
Huntingtin (human) MsGEEEDsDLAAkLG S1880-p
Huntingtin (mouse) KsGEEEDSGSAAQLG S1859
Huntingtin (rat) QISAEEDSGSAAQLG S1850
K1885-ub
EDsDLAAkLGMCNRE
0 1
Huntingtin (human) EDsDLAAkLGMCNRE K1885-ub
Huntingtin (mouse) EDSGSAAQLGMCNRE Q1864
Huntingtin (rat) EDSGSAAQLGMCNRE Q1855
R2051-m2
QSSGLAQrHQRLYSL
1 1