Other Species / Isoforms
  PDHA1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K18-ac
VLSGASQkPASRVLV
Upstream
1 1
Treatment
  • nicotinamide
  • trichostatin_A
PDHA1 (human) VLSGASQkPASRVLV K18-ac
PDHA1 iso2 (human) VLSGASQKPASRVLV K18
PDHA1 (mouse) VLAGSAQKPASRVLV K18
PDHA1 (rat) VLAGAAQKPASRVLV K18
PDHA1 (pig) VLSGVAQKPASRVLV K17
K39-ac
NDATFEIkKCDLHRL
Upstream
1 25
Treatment
  • nicotinamide
  • trichostatin_A
PDHA1 (human) NDATFEIkKCDLHRL K39-ac
PDHA1 iso2 (human) NDATFEIKKCDLHRL K39
PDHA1 (mouse) NDATFEIkKCDLHRL K39-ac
PDHA1 (rat) NDATFEIkKCDLHRL K39-ac
PDHA1 (pig) NDATFEIKKCDLHRL K38
K63-ac
LTREDGLkYYRMMQT
0 4
PDHA1 (human) LTREDGLkYYRMMQT K63-ac
PDHA1 iso2 (human) LTREDGLKYYRMMQT K63
PDHA1 (mouse) LTREDGLkYYRMMQT K63-ac
PDHA1 (rat) LTREDGLkYYRMMQT K63-ac
PDHA1 (pig) LTREDGLKYYRMMQT K62
K63
LTREDGLKYYRMMQT
0 1
PDHA1 (human) LTREDGLKYYRMMQT K63
PDHA1 iso2 (human) LTREDGLKYYRMMQT K63
PDHA1 (mouse) LTREDGLkYYRMMQT K63-sc
PDHA1 (rat) LTREDGLKYYRMMQT K63
PDHA1 (pig) LTREDGLKYYRMMQT K62
K77-ac
TVRRMELkADQLYkQ
0 15
PDHA1 (human) TVRRMELkADQLYkQ K77-ac
PDHA1 iso2 (human) TVRRMELKADQLYKQ K77
PDHA1 (mouse) TVRRMELkADQLYkQ K77-ac
PDHA1 (rat) TVRRMELkADQLYkQ K77-ac
PDHA1 (pig) TVRRMELKADQLYKQ K76
K83-ac
LkADQLYkQKIIRGF
0 11
PDHA1 (human) LkADQLYkQKIIRGF K83-ac
PDHA1 iso2 (human) LKADQLYKQKIIRGF K83
PDHA1 (mouse) LkADQLYkQkIIRGF K83-ac
PDHA1 (rat) LkADQLYkQkIIRGF K83-ac
PDHA1 (pig) LKADQLYKQKIIRGF K82
K83-sc
LkADQLYkQKIIRGF
0 2
PDHA1 (human) LkADQLYkQKIIRGF K83-sc
PDHA1 iso2 (human) LKADQLYKQKIIRGF K83
PDHA1 (mouse) LkADQLYkQkIIRGF K83-sc
PDHA1 (rat) LkADQLYKQkIIRGF K83
PDHA1 (pig) LKADQLYKQKIIRGF K82
K85
ADQLYkQKIIRGFCH
0 2
PDHA1 (human) ADQLYkQKIIRGFCH K85
PDHA1 iso2 (human) ADQLYKQKIIRGFCH K85
PDHA1 (mouse) ADQLYkQkIIRGFCH K85-ac
PDHA1 (rat) ADQLYkQkIIRGFCH K85-ac
PDHA1 (pig) ADQLYKQKIIRGFCH K84
T116-p
NPTDHLItAyRAHGF
0 1
PDHA1 (human) NPTDHLItAyRAHGF T116-p
PDHA1 iso2 (human) NPTDHLITAYRAHGF T123
PDHA1 (mouse) NPTDHLITAYRAHGF T116
PDHA1 (rat) NPTDHLITAYRAHGF T116
PDHA1 (pig) NPTDHLITAYRAHGF T115
Y118-p
TDHLItAyRAHGFTF
0 1
PDHA1 (human) TDHLItAyRAHGFTF Y118-p
PDHA1 iso2 (human) TDHLITAYRAHGFTF Y125
PDHA1 (mouse) TDHLITAYRAHGFTF Y118
PDHA1 (rat) TDHLITAYRAHGFTF Y118
PDHA1 (pig) TDHLITAYRAHGFTF Y117
T139-p
REILAELtGRKGGCA
0 1
PDHA1 (human) REILAELtGRKGGCA T139-p
PDHA1 iso2 (human) REILAELTGRKGGCA T146
PDHA1 (mouse) RAILAELTGRRGGCA T139
PDHA1 (rat) RAILAELTGRRGGCA T139
PDHA1 (pig) REILAELTGRRGGCG T138
Y227-p
FICENNRyGMGtsVE
0 10
PDHA1 (human) FICENNRyGMGtsVE Y227-p
PDHA1 iso2 (human) FICENNRYGMGTSVE Y234
PDHA1 (mouse) FICENNRyGMGtsVE Y227-p
PDHA1 (rat) FICENNRyGMGtsVE Y227-p
PDHA1 (pig) FICENNRYGMGTsVE Y226
T231-p
NNRyGMGtsVERAAA
0 40
PDHA1 (human) NNRyGMGtsVERAAA T231-p
PDHA1 iso2 (human) NNRYGMGTSVERAAA T238
PDHA1 (mouse) NNRyGMGtsVERAAA T231-p
PDHA1 (rat) NNRyGMGtsVERAAA T231-p
PDHA1 (pig) NNRYGMGTsVERAAA T230
S232-p
NRyGMGtsVERAAAS
Upstream
Downstream
34 79
Effects on Modified Protein
  • enzymatic activity, inhibited
Effects on Biological Processes:
  • cell growth, induced
Kinase, in vitro:
  • PDHK1 (human)
  • PDHK2 (human)
  • PDK1 (human)
Phosphatases, in vitro:
  • PDP1 (human)
Regulatory protein:
  • HIF1A (human)
  • PDHK1 (human)
  • PDP1 (human)
  • STAU (human)
Treatment
  • CoCL2
  • DCA
  • desferoxamine
  • dicoumarol
  • DMOG
  • EGF
  • hypoxia
  • JX06
  • metastatic potential
  • MG132
  • nocodazole
  • VER-246608
PDHA1 (human) NRyGMGtsVERAAAS S232-p
PDHA1 iso2 (human) NRYGMGTSVERAAAS S239
PDHA1 (mouse) NRyGMGtsVERAAAS S232-p
PDHA1 (rat) NRyGMGtsVERAAAS S232-p
PDHA1 (pig) NRYGMGTsVERAAAS S231-p
T240-p
VERAAAStDyykrGD
0 1
PDHA1 (human) VERAAAStDyykrGD T240-p
PDHA1 iso2 (human) VERAAASTDYYKRGD T247
PDHA1 (mouse) VERAAASTDyykRGD T240
PDHA1 (rat) VERAAASTDYYkRGD T240
PDHA1 (pig) VERAAASTDYYKRGD T239
Y242-p
RAAAStDyykrGDFI
0 49
PDHA1 (human) RAAAStDyykrGDFI Y242-p
PDHA1 iso2 (human) RAAASTDYYKRGDFI Y249
PDHA1 (mouse) RAAASTDyykRGDFI Y242-p
PDHA1 (rat) RAAASTDYYkRGDFI Y242
PDHA1 (pig) RAAASTDYYKRGDFI Y241
Y243-p
AAAStDyykrGDFIP
0 4
PDHA1 (human) AAAStDyykrGDFIP Y243-p
PDHA1 iso2 (human) AAASTDYYKRGDFIP Y250
PDHA1 (mouse) AAASTDyykRGDFIP Y243-p
PDHA1 (rat) AAASTDYYkRGDFIP Y243
PDHA1 (pig) AAASTDYYKRGDFIP Y242
K244-ac
AAStDyykrGDFIPG
Upstream
1 88
Treatment
  • nicotinamide
  • trichostatin_A
PDHA1 (human) AAStDyykrGDFIPG K244-ac
PDHA1 iso2 (human) AASTDYYKRGDFIPG K251
PDHA1 (mouse) AASTDyykRGDFIPG K244-ac
PDHA1 (rat) AASTDYYkRGDFIPG K244-ac
PDHA1 (pig) AASTDYYKRGDFIPG K243
K244-ub
AAStDyykrGDFIPG
0 2
PDHA1 (human) AAStDyykrGDFIPG K244-ub
PDHA1 iso2 (human) AASTDYYKRGDFIPG K251
PDHA1 (mouse) AASTDyyKRGDFIPG K244
PDHA1 (rat) AASTDYYKRGDFIPG K244
PDHA1 (pig) AASTDYYKRGDFIPG K243
K244-sc
AAStDyykrGDFIPG
0 1
PDHA1 (human) AAStDyykrGDFIPG K244-sc
PDHA1 iso2 (human) AASTDYYKRGDFIPG K251
PDHA1 (mouse) AASTDyykRGDFIPG K244-sc
PDHA1 (rat) AASTDYYKRGDFIPG K244
PDHA1 (pig) AASTDYYKRGDFIPG K243
R245-m1
AStDyykrGDFIPGL
0 1
PDHA1 (human) AStDyykrGDFIPGL R245-m1
PDHA1 iso2 (human) ASTDYYKRGDFIPGL R252
PDHA1 (mouse) ASTDyykRGDFIPGL R245
PDHA1 (rat) ASTDYYkRGDFIPGL R245
PDHA1 (pig) ASTDYYKRGDFIPGL R244
R267
LCVREATRFAAAyCR
0 1
PDHA1 (human) LCVREATRFAAAyCR R267
PDHA1 iso2 (human) LCVREATRFAAAYCR R274
PDHA1 (mouse) LCVREATKFAAAYCR K267
PDHA1 (rat) LCVREATkFAAAYCR K267-ac
PDHA1 (pig) LCVREATRFAAAYCR R266
Y272-p
ATRFAAAyCRSGkGP
0 1
PDHA1 (human) ATRFAAAyCRSGkGP Y272-p
PDHA1 iso2 (human) ATRFAAAYCRSGKGP Y279
PDHA1 (mouse) ATKFAAAYCRSGkGP Y272
PDHA1 (rat) ATkFAAAYCRSGKGP Y272
PDHA1 (pig) ATRFAAAYCRSGKGP Y271
K277-ac
AAyCRSGkGPILMEL
0 26
PDHA1 (human) AAyCRSGkGPILMEL K277-ac
PDHA1 iso2 (human) AAYCRSGKGPILMEL K284
PDHA1 (mouse) AAYCRSGkGPILMEL K277-ac
PDHA1 (rat) AAYCRSGKGPILMEL K277
PDHA1 (pig) AAYCRSGKGPILMEL K276
Y289-p
MELQTYRyHGHsMsD
Upstream
Downstream
1 462
Effects on Modified Protein
  • enzymatic activity, inhibited
Effects on Biological Processes:
  • carcinogenesis, induced
Kinase, in vitro:
  • Src (human)
PDHA1 (human) MELQTYRyHGHsMsD Y289-p
PDHA1 iso2 (human) MELQTYRYHGHsMSD Y296
PDHA1 (mouse) MELQTYRyHGHsMsD Y289-p
PDHA1 (rat) MELQTYRyHGHsMsD Y289-p
PDHA1 (pig) MELQTYRYHGHsMSD Y288
S293-p
TYRyHGHsMsDPGVs
Upstream
Downstream
77 774
PDHA1 (human)
S293-p
PDHA1 iso2 (human)
S300-p
PDHA1 (mouse)
S293-p
PDHA1 (rat)
S293-p
PDHA1 (pig)
S292-p
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
  • enzymatic activity, inhibited
Effects on Biological Processes:
  • cell growth, induced
Kinase, in vitro:
  • PDHK1 (human)
  • PDHK2 (human)
  • PDHK3 (human)
  • PDHK4 (human)
  • PDK1 (human)
Phosphatases, in vitro:
  • PDP1 (human)
Putative in vivo kinases:
  • PDK1 (human)
Putative upstream phosphatases:
  • PDP2 (human)
Regulatory protein:
  • Akt1 (human)
  • BRAF (human)
  • IDH1 (human)
  • Myc (human)
  • PDHK1 (human)
  • PDHK4 (human)
  • PDK1 (human)
  • SULF1 (human)
Treatment
  • 1,25_dihydroxyvitamin_D
  • apitolisib
  • AZD7545
  • butyrate
  • CoCL2
  • CT-99021
  • dactolisib
  • DCA
  • DMOG
  • doxycycline
  • EGF
  • exercise
  • fasting
  • GH
  • glucose_starvation
  • HH-F3
  • high-fat diet
  • high_glucose
  • hypoxia
  • JX06
  • lncRNAs
  • metastatic potential
  • miRNA
  • MK-2206
  • monolayer culture
  • nicotinamide
  • nocodazole
  • normal chow diet
  • siRNA
  • spheroid culture
  • taselisib
  • terbutaline
  • TK1258
  • trichostatin_A
  • U0126
  • VER-246608
PDHA1 (human) TYRyHGHsMsDPGVs S293-p
PDHA1 iso2 (human) TYRYHGHsMSDPGVS S300-p
PDHA1 (mouse) TYRyHGHsMsDPGVs S293-p
PDHA1 (rat) TYRyHGHsMsDPGVs S293-p
PDHA1 (pig) TYRYHGHsMSDPGVs S292-p
S295-p
RyHGHsMsDPGVsyR
Upstream
2 287
Treatment
  • exercise
  • metastatic potential
  • nocodazole
PDHA1 (human) RyHGHsMsDPGVsyR S295-p
PDHA1 iso2 (human) RYHGHsMSDPGVSYR S302
PDHA1 (mouse) RyHGHsMsDPGVsyR S295-p
PDHA1 (rat) RyHGHsMsDPGVsyR S295-p
PDHA1 (pig) RYHGHsMSDPGVsYR S294
S300-p
sMsDPGVsyRtREEI
Upstream
Downstream
42 547
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, inhibited
Kinase, in vitro:
  • PDHK1 (human)
  • PDHK2 (human)
  • PDHK3 (human)
  • PDHK4 (human)
  • PDK1 (human)
Phosphatases, in vitro:
  • PDP1 (human)
Regulatory protein:
  • IDH1 (human)
  • PDHK4 (human)
Treatment
  • AZD7545
  • BGT226
  • CoCL2
  • dactolisib
  • DCA
  • desferoxamine
  • DMOG
  • EGF
  • exercise
  • fasting
  • GH
  • high-fat diet
  • hypoxia
  • ischemia
  • metastatic potential
  • terbutaline
  • VER-246608
PDHA1 (human) sMsDPGVsyRtREEI S300-p
PDHA1 iso2 (human) sMSDPGVSYRTREEI S307
PDHA1 (mouse) sMsDPGVsyRtREEI S300-p
PDHA1 (rat) sMsDPGVsyRTREEI S300-p
PDHA1 (pig) sMSDPGVsYRTREEI S299-p
Y301-p
MsDPGVsyRtREEIQ
Upstream
2 1416
Regulatory protein:
  • EGFR (human)
Treatment
  • EGF
  • U0126
PDHA1 (human) MsDPGVsyRtREEIQ Y301-p
PDHA1 iso2 (human) MSDPGVSYRTREEIQ Y308
PDHA1 (mouse) MsDPGVsyRtREEIQ Y301-p
PDHA1 (rat) MsDPGVsyRTREEIQ Y301-p
PDHA1 (pig) MSDPGVsYRTREEIQ Y300
T303-p
DPGVsyRtREEIQEV
0 43
PDHA1 (human) DPGVsyRtREEIQEV T303-p
PDHA1 iso2 (human) DPGVSYRTREEIQEV T310
PDHA1 (mouse) DPGVsyRtREEIQEV T303-p
PDHA1 (rat) DPGVsyRTREEIQEV T303
PDHA1 (pig) DPGVsYRTREEIQEV T302
K313-ac
EIQEVRSkSDPIMLL
0 25
PDHA1 (human) EIQEVRSkSDPIMLL K313-ac
PDHA1 iso2 (human) EIQEVRSKSDPIMLL K320
PDHA1 (mouse) EIQEVRSkSDPIMLL K313-ac
PDHA1 (rat) EIQEVRSkSDPIMLL K313-ac
PDHA1 (pig) EIQEVRSKSDPIMLL K312
K321-ac
SDPIMLLkDRMVNSN
Upstream
Downstream
2 83
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, induced
Treatment
  • dovitinib
  • EGF
  • MS275
  • nicotinamide
  • trichostatin_A
  • vorinostat
PDHA1 (human) SDPIMLLkDRMVNSN K321-ac
PDHA1 iso2 (human) SDPIMLLKDRMVNSN K328
PDHA1 (mouse) SDPIMLLkDRMVNSN K321-ac
PDHA1 (rat) SDPIMLLkDRMVNSN K321-ac
PDHA1 (pig) SDPIMLLKDRMVNSN K320
K321
SDPIMLLKDRMVNSN
0 1
PDHA1 (human) SDPIMLLKDRMVNSN K321
PDHA1 iso2 (human) SDPIMLLKDRMVNSN K328
PDHA1 (mouse) SDPIMLLkDRMVNSN K321-ub
PDHA1 (rat) SDPIMLLKDRMVNSN K321
PDHA1 (pig) SDPIMLLKDRMVNSN K320
K321-sc
SDPIMLLkDRMVNSN
0 2
PDHA1 (human) SDPIMLLkDRMVNSN K321-sc
PDHA1 iso2 (human) SDPIMLLKDRMVNSN K328
PDHA1 (mouse) SDPIMLLkDRMVNSN K321-sc
PDHA1 (rat) SDPIMLLKDRMVNSN K321
PDHA1 (pig) SDPIMLLKDRMVNSN K320
S331
MVNSNLASVEELkEI
0 2
PDHA1 (human) MVNSNLASVEELkEI S331
PDHA1 iso2 (human) MVNSNLASVEELKEI S338
PDHA1 (mouse) MVNSNLAsVEELkEI S331-p
PDHA1 (rat) MVNSNLASVEELkEI S331
PDHA1 (pig) MVNSNLASVEELKEI S330
K336-ac
LASVEELkEIDVEVR
1 5
PDHA1 (human) LASVEELkEIDVEVR K336-ac
PDHA1 iso2 (human) LASVEELKEIDVEVR K343
PDHA1 (mouse) LAsVEELkEIDVEVR K336-ac
PDHA1 (rat) LASVEELkEIDVEVR K336-ac
PDHA1 (pig) LASVEELKEIDVEVR K335
K336
LASVEELKEIDVEVR
0 1
PDHA1 (human) LASVEELKEIDVEVR K336
PDHA1 iso2 (human) LASVEELKEIDVEVR K343
PDHA1 (mouse) LAsVEELkEIDVEVR K336-sc
PDHA1 (rat) LASVEELKEIDVEVR K336
PDHA1 (pig) LASVEELKEIDVEVR K335
K344
EIDVEVRKEIEDAAQ
0 1
PDHA1 (human) EIDVEVRKEIEDAAQ K344
PDHA1 iso2 (human) EIDVEVRKEIEDAAQ K351
PDHA1 (mouse) EIDVEVRkEIEDAAQ K344-sc
PDHA1 (rat) EIDVEVRKEIEDAAQ K344
PDHA1 (pig) EIDVEVRKEIEDAAQ K343
Y366-p
PPLEELGyHIySSDP
0 1
PDHA1 (human) PPLEELGyHIySSDP Y366-p
PDHA1 iso2 (human) PPLEELGYHIYSSDP Y373
PDHA1 (mouse) PPLEELGYHIYSSDP Y366
PDHA1 (rat) PPLEELGYHIYSSDP Y366
PDHA1 (pig) PPLEELGYHIYCNDP Y365
Y369-p
EELGyHIySSDPPFE
0 1
PDHA1 (human) EELGyHIySSDPPFE Y369-p
PDHA1 iso2 (human) EELGYHIYSSDPPFE Y376
PDHA1 (mouse) EELGYHIYSSDPPFE Y369
PDHA1 (rat) EELGYHIYSSDPPFE Y369
PDHA1 (pig) EELGYHIYCNDPPFE Y368
K385
RGANQWIKFKSVS__
0 3
PDHA1 (human) RGANQWIKFKSVS__ K385
PDHA1 iso2 (human) RGANQWIKFKSVS__ K392
PDHA1 (mouse) RGANQWIkFKSVS__ K385-ac
PDHA1 (rat) RGANQWIkFKSVS__ K385-ac
PDHA1 (pig) RGANQWIKFKSIS__ K384
K385-m1
RGANQWIkFKSVS__
0 1
PDHA1 (human) RGANQWIkFKSVS__ K385-m1
PDHA1 iso2 (human) RGANQWIKFKSVS__ K392
PDHA1 (mouse) RGANQWIKFKSVS__ K385
PDHA1 (rat) RGANQWIKFKSVS__ K385
PDHA1 (pig) RGANQWIKFKSIS__ K384
K385
RGANQWIKFKSVS__
0 1
PDHA1 (human) RGANQWIKFKSVS__ K385
PDHA1 iso2 (human) RGANQWIKFKSVS__ K392
PDHA1 (mouse) RGANQWIkFKSVS__ K385-ub
PDHA1 (rat) RGANQWIKFKSVS__ K385
PDHA1 (pig) RGANQWIKFKSIS__ K384