Other Species / Isoforms
  TIE2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T115-p
GEAIRIRtMKMRQQA
0 1
TIE2 (human) GEAIRIRtMKMRQQA T115-p
TIE2 (mouse) GQAIRIRTMKMRQQA T115
N140
VDKGDNVNIsFKKVL
0 1
TIE2 (human) VDKGDNVNIsFKKVL N140
TIE2 (mouse) VDRGDNVnISFKKVL N140-ng
S142-p
KGDNVNIsFKKVLIK
0 1
TIE2 (human) KGDNVNIsFKKVLIK S142-p
TIE2 (mouse) RGDNVnISFKKVLIK S142
N158
EDAVIYKNGSFIHsV
0 1
TIE2 (human) EDAVIYKNGSFIHsV N158
TIE2 (mouse) EDAVIYKnGSFIHSV N158-ng
S164-p
KNGSFIHsVPRHEVP
0 1
TIE2 (human) KNGSFIHsVPRHEVP S164-p
TIE2 (mouse) KnGSFIHSVPRHEVP S164
N399
VLHPKDFNHTDHFSV
0 1
TIE2 (human) VLHPKDFNHTDHFSV N399
TIE2 (mouse) VLQPNDFnYTDRFSV N399-ng
N464
GHNFAVINISSEPYF
0 1
TIE2 (human) GHNFAVINISSEPYF N464
TIE2 (mouse) GHNFAIInISSEPYF N464-ng
N596
QNIKVPGNLTSVLLN
0 1
TIE2 (human) QNIKVPGNLTSVLLN N596
TIE2 (mouse) QNIKVPGnLTSVLLS N595-ng
N691
HVDVKIKNATITQyQ
0 1
TIE2 (human) HVDVKIKNATITQyQ N691
TIE2 (mouse) HIDVKIKnATVTQYQ N690-ng
Y697-p
KNATITQyQLKGLEP
0 1
TIE2 (human) KNATITQyQLKGLEP Y697-p
TIE2 (mouse) KnATVTQYQLKGLEP Y696
Y816-p
NNPDPTIyPVLDWND
0 1
TIE2 (human) NNPDPTIyPVLDWND Y816-p
TIE2 (mouse) NNPDPTIYPVLDWND Y814
Y897-p
GACEHRGyLyLAIEY
Downstream
1 26
Effects on Modified Protein
  • enzymatic activity, inhibited
TIE2 (human) GACEHRGyLyLAIEY Y897-p
TIE2 (mouse) GACEHRGYLYLAIEY Y895
Y899-p
CEHRGyLyLAIEYAP
0 1
TIE2 (human) CEHRGyLyLAIEYAP Y899-p
TIE2 (mouse) CEHRGYLYLAIEYAP Y897
Y976-p
NILVGENyVAKIADF
0 11
TIE2 (human) NILVGENyVAKIADF Y976-p
TIE2 (mouse) NILVGENYIAKIADF Y974
Y992-p
LSRGQEVyVKKTMGR
Upstream
Downstream
4 0
TIE2 (human)
Y992-p
TIE2 (mouse)
Y990-p
Effects on Modified Protein
  • activity, induced
  • protein conformation
Kinase, in vitro:
  • TIE2 (human)
Regulatory protein:
  • EPCR (human)
  • F10 (human)
  • PAR3 (human)
Treatment
  • angiopoietin-1
TIE2 (human) LSRGQEVyVKKTMGR Y992-p
TIE2 (mouse) LSRGQEVYVKKTMGR Y990
Y1048-p
GMTCAELyEKLPQGY
1 0
TIE2 (human) GMTCAELyEKLPQGY Y1048-p
TIE2 (mouse) GMTCAELYEKLPQGY Y1046
Y1102-p
MLEERKTyVNTTLyE
Downstream
5 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell adhesion, altered
TIE2 (human) MLEERKTyVNTTLyE Y1102-p
TIE2 (mouse) MLEERKTyVNTTLyE Y1100-p
Y1108-p
TyVNTTLyEKFTyAG
Upstream
Downstream
4 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • TIE2 (human)
TIE2 (human) TyVNTTLyEKFTyAG Y1108-p
TIE2 (mouse) TyVNTTLyEKFTyAG Y1106-p
Y1113-p
TLyEKFTyAGIDCsA
3 0
TIE2 (human) TLyEKFTyAGIDCsA Y1113-p
TIE2 (mouse) TLyEKFTyAGIDCsA Y1111-p
S1119-p
TyAGIDCsAEEAA__
Upstream
Downstream
1 3
TIE2 (human)
S1119-p
TIE2 (mouse)
S1117-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
Regulatory protein:
  • EPCR (human)
  • F10 (human)
  • PAR3 (human)
TIE2 (human) TyAGIDCsAEEAA__ S1119-p
TIE2 (mouse) TyAGIDCsAEEAA__ S1117-p