Other Species / Isoforms
  PLCG2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y13
NVDSLAEYEKSQIKR
0 1
PLCG2 (human) NVDSLAEYEKSQIKR Y13
PLCG2 (mouse) NVDTLPEyEKSQIKR Y13-p
PLCG2 (rat) NVDTLPEYEKSQIKR Y13
T49
TVQVIMETRQVAWSK
0 1
PLCG2 (human) TVQVIMETRQVAWSK T49
PLCG2 (mouse) TVQMIMEtRQVAWSK T49-p
PLCG2 (rat) TVQMIMETRQVAWSK T49
S160-p
VDQTRRNsISLRELk
0 8
PLCG2 (human) VDQTRRNsISLRELk S160-p
PLCG2 (mouse) VDQTRRNsISLRELK S160-p
PLCG2 (rat) VDQTRRNSISLRELK S160
K167-ub
sISLRELkTILPLIN
0 1
PLCG2 (human) sISLRELkTILPLIN K167-ub
PLCG2 (mouse) sISLRELKTILPLVN K167
PLCG2 (rat) SISLRELKTILPLVN K167
K208-ub
QFHLFYKkLMFEQQK
0 1
PLCG2 (human) QFHLFYKkLMFEQQK K208-ub
PLCG2 (mouse) QFHLFYKKLMFDQQK K208
PLCG2 (rat) QFHLFYKKLMFEQQK K208
K222-ub
KSILDEFkKDSSVFI
0 1
PLCG2 (human) KSILDEFkKDSSVFI K222-ub
PLCG2 (mouse) KSILDEFKKDSSVFI K222
PLCG2 (rat) KSILDEFKKDSSVFI K222
Y242-p
RPDASAVyLHDFQRF
0 5
PLCG2 (human) RPDASAVyLHDFQRF Y242-p
PLCG2 (mouse) RPDASAVyLQDFQRF Y242-p
PLCG2 (rat) RPDASAVYLQDFQRF Y242
T276-p
MTKFIDDtMRETAEP
0 1
PLCG2 (human) MTKFIDDtMRETAEP T276-p
PLCG2 (mouse) MTKFIDDTMRETAEP T276
PLCG2 (rat) MTKFIDDTMRETAEP T276
Y371-p
PDGKPVIyHGWTRTT
0 44
PLCG2 (human) PDGKPVIyHGWTRTT Y371-p
PLCG2 (mouse) PDGKPIIyHGWtRTT Y371-p
PLCG2 (rat) PDGKPIIYHGWTRTT Y371
T375
PVIyHGWTRTTKIKF
0 1
PLCG2 (human) PVIyHGWTRTTKIKF T375
PLCG2 (mouse) PIIyHGWtRTTKIKF T375-p
PLCG2 (rat) PIIYHGWTRTTKIKF T375
K432-ub
FGDLLLTkPTEASAD
0 6
PLCG2 (human) FGDLLLTkPTEASAD K432-ub
PLCG2 (mouse) LGDMLLTKPTEASAD K432
PLCG2 (rat) LGDLLLTKPTEASAD K432
Y482-p
HKQQGELyMWDSIDQ
0 14
PLCG2 (human) HKQQGELyMWDSIDQ Y482-p
PLCG2 (mouse) HKPQGELyMWDSIDQ Y482-p
PLCG2 (rat) HKTQGELYMWDSIDQ Y482
Y495-p
DQKWTRHyCAIADAK
Upstream
1 35
Treatment
  • EGF
PLCG2 (human) DQKWTRHyCAIADAK Y495-p
PLCG2 (mouse) DQKWTRHyCAIADAK Y495-p
PLCG2 (rat) DQKWTRHYCAIADAK Y495
K557-ub
YCMETGGkDGTFLVR
0 1
PLCG2 (human) YCMETGGkDGTFLVR K557-ub
PLCG2 (mouse) YCAETGAKDGTFLVR K557
PLCG2 (rat) YCAETGAKDGTFLVR K557
Y647-p
PHESKPWyYDSLSRG
0 1
PLCG2 (human) PHESKPWyYDSLSRG Y647-p
PLCG2 (mouse) PHESKPWYYDSLSRG Y647
PLCG2 (rat) PHESKPWYYDRLSRG Y647
S677-p
LIRKREGsDsyAItF
0 3
PLCG2 (human) LIRKREGsDsyAItF S677-p
PLCG2 (mouse) LIRKREGTNsyAITF T677
PLCG2 (rat) LIRKREGTDSYAITF T677
S679-p
RKREGsDsyAItFRA
0 2
PLCG2 (human) RKREGsDsyAItFRA S679-p
PLCG2 (mouse) RKREGTNsyAITFRA S679-p
PLCG2 (rat) RKREGTDSYAITFRA S679
Y680-p
KREGsDsyAItFRAR
0 55
PLCG2 (human) KREGsDsyAItFRAR Y680-p
PLCG2 (mouse) KREGTNsyAITFRAR Y680-p
PLCG2 (rat) KREGTDSYAITFRAR Y680
T683-p
GsDsyAItFRARGKV
0 1
PLCG2 (human) GsDsyAItFRARGKV T683-p
PLCG2 (mouse) GTNsyAITFRARGKV T683
PLCG2 (rat) GTDSYAITFRARGKV T683
Y720-p
LVELVSYyEKHSLYR
0 1
PLCG2 (human) LVELVSYyEKHSLYR Y720-p
PLCG2 (mouse) LVELVSYYEKHALYR Y720
PLCG2 (rat) LVELVSYYEKHALYR Y720
Y733-p
YRKMRLRyPVTPELL
0 3
PLCG2 (human) YRKMRLRyPVTPELL Y733-p
PLCG2 (mouse) YRKMRLRYPVTPELL Y733
PLCG2 (rat) YRKMRLRYPVTPELL Y733
Y743-p
TPELLERyNMERDIN
0 1
PLCG2 (human) TPELLERyNMERDIN Y743-p
PLCG2 (mouse) TPELLERYNMERDIN Y743
PLCG2 (rat) TPELLERYNMERDIN Y743
Y753-p
ERDINSLyDVsRMyV
Upstream
Downstream
10 278
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Kinase, in vitro:
  • Btk (human)
  • Fyn (human)
  • Lck (human)
  • Src (human)
Putative in vivo kinases:
  • Btk (human)
Regulatory protein:
  • ZAP70 (human)
Treatment
  • acalabrutinib
  • anti-CD3
  • anti-IgM
  • bisindolylmaleimide
  • collagen
  • convulxin
  • H2O2
  • ibrutinib
  • LFM-A13
  • LY294002
  • PDGF
  • phorbol_ester
  • PP1
  • ristocetin
  • vanadate
  • von_Willebrand_factor
PLCG2 (human) ERDINSLyDVsRMyV Y753-p
PLCG2 (mouse) ERDINSLyDVSRMyV Y753-p
PLCG2 (rat) ERDINSLyDVSRMyV Y753-p
S756-p
INSLyDVsRMyVDPs
0 4
PLCG2 (human) INSLyDVsRMyVDPs S756-p
PLCG2 (mouse) INSLyDVSRMyVDPS S756
PLCG2 (rat) INSLyDVSRMyVDPS S756
Y759-p
LyDVsRMyVDPsEIN
Upstream
Downstream
11 232
PLCG2 (human)
Y759-p
PLCG2 (mouse)
Y759-p
PLCG2 (rat)
Y759-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Kinase, in vitro:
  • Btk (human)
  • Fyn (human)
  • Lck (human)
  • Src (human)
  • Syk (human)
Putative in vivo kinases:
  • Btk (human)
Regulatory protein:
  • Btk (human)
  • FGFR1 (human)
Treatment
  • anti-CD19
  • anti-CD3
  • anti-IgM
  • bisindolylmaleimide
  • convulxin
  • CXCL12
  • H2O2
  • IL-15
  • IL-2
  • LFM-A13
  • LY294002
  • PDGF
  • phorbol_ester
  • PP1
  • ristocetin
  • vanadate
  • von_Willebrand_factor
  • wortmannin
PLCG2 (human) LyDVsRMyVDPsEIN Y759-p
PLCG2 (mouse) LyDVSRMyVDPSEIN Y759-p
PLCG2 (rat) LyDVSRMyVDPSEIN Y759-p
S763-p
sRMyVDPsEINPSMP
0 1
PLCG2 (human) sRMyVDPsEINPSMP S763-p
PLCG2 (mouse) SRMyVDPSEINPSMP S763
PLCG2 (rat) SRMyVDPSEINPSMP S763
K775-ub
SMPQRTVkALyDyKA
0 1
PLCG2 (human) SMPQRTVkALyDyKA K775-ub
PLCG2 (mouse) SMPQRTVKALYDYKA K775
PLCG2 (rat) SMPQRTVKALYDYKA K775
Y778-p
QRTVkALyDyKAKRS
0 6
PLCG2 (human) QRTVkALyDyKAKRS Y778-p
PLCG2 (mouse) QRTVKALYDYKAKRS Y778
PLCG2 (rat) QRTVKALYDYKAKRS Y778
Y780-p
TVkALyDyKAKRSDE
0 1
PLCG2 (human) TVkALyDyKAKRSDE Y780-p
PLCG2 (mouse) TVKALYDYKAKRSDE Y780
PLCG2 (rat) TVKALYDYKAKRSDE Y780
S789-p
AKRSDELsFCRGALI
0 1
PLCG2 (human) AKRSDELsFCRGALI S789-p
PLCG2 (mouse) AKRSDELTFCRGALI T789
PLCG2 (rat) AKRSDELTFCRGALI T789
Y811-p
GGWWKGDyGTRIQQy
0 6
PLCG2 (human) GGWWKGDyGTRIQQy Y811-p
PLCG2 (mouse) GGWWKGDyGTRIQQy Y811-p
PLCG2 (rat) GGWWKGDYGTRIQQY Y811
Y818-p
yGTRIQQyFPSNYVE
Upstream
0 13
Treatment
  • imatinib
PLCG2 (human) yGTRIQQyFPSNYVE Y818-p
PLCG2 (mouse) yGTRIQQyFPSNyVE Y818-p
PLCG2 (rat) YGTRIQQYFPSNYVE Y818
Y823
QQyFPSNYVEDISTA
0 1
PLCG2 (human) QQyFPSNYVEDISTA Y823
PLCG2 (mouse) QQyFPSNyVEDISAG Y823-p
PLCG2 (rat) QQYFPSNYVEDISAG Y823
T857-p
RGILDLNtyNVVkAP
0 4
PLCG2 (human) RGILDLNtyNVVkAP T857-p
PLCG2 (mouse) KGILDLNTYNVVKAP T857
PLCG2 (rat) RGILDLNTYNVVkAP T857
Y858-p
GILDLNtyNVVkAPQ
0 16
PLCG2 (human) GILDLNtyNVVkAPQ Y858-p
PLCG2 (mouse) GILDLNTYNVVKAPQ Y858
PLCG2 (rat) GILDLNTYNVVkAPQ Y858
K862
LNtyNVVKAPQGKNQ
0 1
PLCG2 (human) LNtyNVVKAPQGKNQ K862
PLCG2 (mouse) LNTYNVVKAPQGKNQ K862
PLCG2 (rat) LNTYNVVkAPQGKNQ K862-ac
K862-ub
LNtyNVVkAPQGKNQ
0 1
PLCG2 (human) LNtyNVVkAPQGKNQ K862-ub
PLCG2 (mouse) LNTYNVVKAPQGKNQ K862
PLCG2 (rat) LNTYNVVKAPQGKNQ K862
Y936-p
ELSDLVVyCKPTsKT
0 9
PLCG2 (human) ELSDLVVyCKPTsKT Y936-p
PLCG2 (mouse) ELSDLVVYCKPTSKT Y936
PLCG2 (rat) ELSDLVVyCKPTSKT Y936-p
S941-p
VVyCKPTsKTKDNLE
0 1
PLCG2 (human) VVyCKPTsKTKDNLE S941-p
PLCG2 (mouse) VVYCKPTSKTKDHLE S941
PLCG2 (rat) VVyCKPTSKTKDHLE S941
S957-p
PDFREIRsFVETkAD
0 2
PLCG2 (human) PDFREIRsFVETkAD S957-p
PLCG2 (mouse) PDFREIRSFVETKAD S957
PLCG2 (rat) PDFREIRSFVETKAD S957
K962-ub
IRsFVETkADsIIRQ
0 3
PLCG2 (human) IRsFVETkADsIIRQ K962-ub
PLCG2 (mouse) IRSFVETKADSIVRQ K962
PLCG2 (rat) IRSFVETKADSIVRQ K962
S965-p
FVETkADsIIRQKPV
0 3
PLCG2 (human) FVETkADsIIRQKPV S965-p
PLCG2 (mouse) FVETKADSIVRQKPV S965
PLCG2 (rat) FVETKADSIVRQKPV S965
K980-ub
DLLKYNQkGLTRVYP
0 2
PLCG2 (human) DLLKYNQkGLTRVYP K980-ub
PLCG2 (mouse) DLLRYNQKGLTRVYP K980
PLCG2 (rat) DLLRYNQKGLTRVYP K980
S994-p
PKGQRVDsSNYDPFR
0 1
PLCG2 (human) PKGQRVDsSNYDPFR S994-p
PLCG2 (mouse) PKGQRVDSSNYDPFR S994
PLCG2 (rat) PKGQRVDSSNYDPFR S994
S1007-p
FRLWLCGsQMVALNF
0 1
PLCG2 (human) FRLWLCGsQMVALNF S1007-p
PLCG2 (mouse) FRLWLCGSQMVALNF S1007
PLCG2 (rat) FRLWLCGSQMVALNF S1007
T1016-p
MVALNFQtADKyMQM
0 1
PLCG2 (human) MVALNFQtADKyMQM T1016-p
PLCG2 (mouse) MVALNFQTPDKYMQM T1016
PLCG2 (rat) MVALNFQTPDKYMQM T1016
Y1020-p
NFQtADKyMQMNHAL
0 2
PLCG2 (human) NFQtADKyMQMNHAL Y1020-p
PLCG2 (mouse) NFQTPDKYMQMNHAL Y1020
PLCG2 (rat) NFQTPDKYMQMNHAL Y1020
S1029-p
QMNHALFsLNGRtGy
0 3
PLCG2 (human) QMNHALFsLNGRtGy S1029-p
PLCG2 (mouse) QMNHALFSLNGRTGY S1029
PLCG2 (rat) QMNHALFSLNGRTGY S1029
T1034-p
LFsLNGRtGyVLQPE
0 1
PLCG2 (human) LFsLNGRtGyVLQPE T1034-p
PLCG2 (mouse) LFSLNGRTGYVLQPE T1034
PLCG2 (rat) LFSLNGRTGYVLQPE T1034
Y1036-p
sLNGRtGyVLQPESM
0 1
PLCG2 (human) sLNGRtGyVLQPESM Y1036-p
PLCG2 (mouse) SLNGRTGYVLQPESM Y1036
PLCG2 (rat) SLNGRTGYVLQPESM Y1036
T1045-p
LQPESMRtEkyDPMP
Upstream
Downstream
1 0
Effects on Biological Processes:
  • signaling pathway regulation
Putative in vivo kinases:
  • ChaK1 (human)
PLCG2 (human) LQPESMRtEkyDPMP T1045-p
PLCG2 (mouse) LQPESMRSEKYDPMP S1045
PLCG2 (rat) LQPESMRSEKYDPMP S1045
K1047-ub
PESMRtEkyDPMPPE
0 1
PLCG2 (human) PESMRtEkyDPMPPE K1047-ub
PLCG2 (mouse) PESMRSEKYDPMPLE K1047
PLCG2 (rat) PESMRSEKYDPMPPE K1047
Y1048-p
ESMRtEkyDPMPPES
0 2
PLCG2 (human) ESMRtEkyDPMPPES Y1048-p
PLCG2 (mouse) ESMRSEKYDPMPLES Y1048
PLCG2 (rat) ESMRSEKYDPMPPES Y1048
T1062-p
SQRKILMtLtVKVLG
0 1
PLCG2 (human) SQRKILMtLtVKVLG T1062-p
PLCG2 (mouse) SQRKILMTLTVKVLG T1062
PLCG2 (rat) SQRKILMTLTVKVLG T1062
T1064-p
RKILMtLtVKVLGAR
0 1
PLCG2 (human) RKILMtLtVKVLGAR T1064-p
PLCG2 (mouse) RKILMTLTVKVLGAR T1064
PLCG2 (rat) RKILMTLTVKVLGAR T1064
Y1137-p
AFLRFVVyEEDMFSD
0 2
PLCG2 (human) AFLRFVVyEEDMFSD Y1137-p
PLCG2 (mouse) AFLRFVVYEEDMFSD Y1137
PLCG2 (rat) AFLRFLVYEEDMFSD Y1137
S1164-p
AVKSGFRsVPLKNGY
Upstream
Downstream
1 0
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • ChaK1 (human)
Putative in vivo kinases:
  • ChaK1 (human)
PLCG2 (human) AVKSGFRsVPLKNGY S1164-p
PLCG2 (mouse) GIKSGFRSVPLKNGY S1164
PLCG2 (rat) GIKSGFRSVPLKNGY S1164
Y1197-p
LESEEELySSCRQLR
Upstream
Downstream
4 87
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • Lck (human)
Treatment
  • anti-CD3
  • anti-IgM
  • convulxin
  • PDGF
  • vanadate
PLCG2 (human) LESEEELySSCRQLR Y1197-p
PLCG2 (mouse) LESEEELySSCRQLR Y1197-p
PLCG2 (rat) LESEEELySSCRQLR Y1197-p
Y1217-p
LNNQLFLyDtHQNLR
Upstream
Downstream
9 354
PLCG2 (human)
Y1217-p
PLCG2 (mouse)
Y1217-p
PLCG2 (rat)
Y1217-p
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • Lck (human)
Regulatory protein:
  • Btk (human)
Treatment
  • anti-CD3
  • anti-IgM
  • bisindolylmaleimide
  • convulxin
  • CXCL12
  • ephrin_B1
  • LFM-A13
  • LY294002
  • PDGF
  • phorbol_ester
  • PP1
  • vanadate
  • wortmannin
PLCG2 (human) LNNQLFLyDtHQNLR Y1217-p
PLCG2 (mouse) LNNQLFLyDTHQNLR Y1217-p
PLCG2 (rat) LNNQLFLyDTHQNLR Y1217-p
T1219-p
NQLFLyDtHQNLRNA
0 17
PLCG2 (human) NQLFLyDtHQNLRNA T1219-p
PLCG2 (mouse) NQLFLyDTHQNLRGA T1219
PLCG2 (rat) NQLFLyDTHQNLRGA T1219
K1233-ub
ANRDALVkEFsVNEN
0 1
PLCG2 (human) ANRDALVkEFsVNEN K1233-ub
PLCG2 (mouse) ANRDALVKEFNVNEN K1233
PLCG2 (rat) ANRDALVKEFNVNEN K1233
S1236-p
DALVkEFsVNENQLQ
0 1
PLCG2 (human) DALVkEFsVNENQLQ S1236-p
PLCG2 (mouse) DALVKEFNVNENQLQ N1236
PLCG2 (rat) DALVKEFNVNENQLR N1236
Y1245-p
NENQLQLyQEkCNKR
Upstream
0 151
Treatment
  • imatinib
PLCG2 (human) NENQLQLyQEkCNKR Y1245-p
PLCG2 (mouse) NENQLQLyQEKCNRR Y1245-p
PLCG2 (rat) NENQLRLYQEKCNRR Y1245
K1248-ub
QLQLyQEkCNKRLRE
0 1
PLCG2 (human) QLQLyQEkCNKRLRE K1248-ub
PLCG2 (mouse) QLQLyQEKCNRRLRE K1248
PLCG2 (rat) QLRLYQEKCNRRLRE K1248
S1259-p
RLREKRVsNskFys_
0 23
PLCG2 (human) RLREKRVsNskFys_ S1259-p
PLCG2 (mouse) RLREKRVsNsRFYS_ S1259-p
PLCG2 (rat) RLREKRVSNSRFYS_ S1259
S1261-p
REKRVsNskFys___
0 2
PLCG2 (human) REKRVsNskFys___ S1261-p
PLCG2 (mouse) REKRVsNsRFYS___ S1261-p
PLCG2 (rat) REKRVSNSRFYS___ S1261
K1262-ub
EKRVsNskFys____
0 1
PLCG2 (human) EKRVsNskFys____ K1262-ub
PLCG2 (mouse) EKRVsNsRFYS____ R1262
PLCG2 (rat) EKRVSNSRFYS____ R1262
Y1264-p
RVsNskFys______
Upstream
0 45
Treatment
  • imatinib
PLCG2 (human) RVsNskFys______ Y1264-p
PLCG2 (mouse) RVsNsRFYS______ Y1264
PLCG2 (rat) RVSNSRFYS______ Y1264
S1265-p
VsNskFys_______
0 3
PLCG2 (human) VsNskFys_______ S1265-p
PLCG2 (mouse) VsNsRFYS_______ S1265
PLCG2 (rat) VSNSRFYS_______ S1265