Other Species / Isoforms
  eIF2B-epsilon (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
P4
____MAAPVVAPPGV
0 1
eIF2B-epsilon (human) ____MAAPVVAPPGV P4
eIF2B-epsilon (mouse) ____MAAtAAVPGAA T4-p
eIF2B-epsilon (rat) ____MAATAAVPSAV T4
eIF2B-epsilon (rabbit) ____MATTVVAPPGA T4
N17
GVVVSRANKRsGAGP
0 3
eIF2B-epsilon (human) GVVVSRANKRsGAGP N17
eIF2B-epsilon (mouse) GAAAGRAsKrGGGGS S16-p
eIF2B-epsilon (rat) SAVGGRANKRGGGsG N16
eIF2B-epsilon (rabbit) GAVSDRANKRGGGPG N17
R19
VVSRANKRsGAGPGG
0 13
eIF2B-epsilon (human) VVSRANKRsGAGPGG R19
eIF2B-epsilon (mouse) AAGRAsKrGGGGSGG R18-m1
eIF2B-epsilon (rat) VGGRANKRGGGsGGG R18
eIF2B-epsilon (rabbit) VSDRANKRGGGPGGG R19
S20-p
VSRANKRsGAGPGGs
0 1
eIF2B-epsilon (human) VSRANKRsGAGPGGs S20-p
eIF2B-epsilon (mouse) AGRAsKrGGGGSGGG G19
eIF2B-epsilon (rat) GGRANKRGGGsGGGG G19
eIF2B-epsilon (rabbit) SDRANKRGGGPGGGG G20
S27-p
sGAGPGGsGGGGARG
1 1
eIF2B-epsilon (human) sGAGPGGsGGGGARG S27-p
eIF2B-epsilon (mouse) sKrGGGGSGGGGTQG S23
eIF2B-epsilon (rat) ANKRGGGsGGGGTQG S22-p
eIF2B-epsilon (rabbit) GGGPGGGGGGGGARG G27
K61-ub
RRFFPISkDQPRVLL
1 1
eIF2B-epsilon (human) RRFFPISkDQPRVLL K61-ub
eIF2B-epsilon (mouse) RRFFPISKDQPRVLL K57
eIF2B-epsilon (rat) RRFFPISkDQPRVLL K56-ub
eIF2B-epsilon (rabbit) RRFFPISKDQPRVLL K61
K103-ub
CWKAAQIkEHLLkSK
1 2
eIF2B-epsilon (human) CWKAAQIkEHLLkSK K103-ub
eIF2B-epsilon (mouse) CWKAAQIKEHLQKSK K99
eIF2B-epsilon (rat) CWKAAQIkEHLQKSK K98-ub
eIF2B-epsilon (rabbit) CWKAAQIKEHLQKSK K103
K108-ub
QIkEHLLkSKWCRPT
0 1
eIF2B-epsilon (human) QIkEHLLkSKWCRPT K108-ub
eIF2B-epsilon (mouse) QIKEHLQKSKWCHPT K104
eIF2B-epsilon (rat) QIkEHLQKSKWCHPT K103
eIF2B-epsilon (rabbit) QIKEHLQKSKWCRPT K108
S130
ITSELYRSLGDVLRD
1 0
eIF2B-epsilon (human) ITSELYRSLGDVLRD S130
eIF2B-epsilon (mouse) ITSELYRSLGDVLRD S126
eIF2B-epsilon (rat) ITSDLYRsLGDVLRD S125-p
eIF2B-epsilon (rabbit) ITSELYRSLGDVLRD S130
K141-ub
VLRDVDAkALVRSDF
1 3
eIF2B-epsilon (human) VLRDVDAkALVRSDF K141-ub
eIF2B-epsilon (mouse) VLRDVDAKALVRSDF K137
eIF2B-epsilon (rat) VLRDVDAkALVRSDF K136-ub
eIF2B-epsilon (rabbit) VLRDVDAKALVRSDF K141
T182-p
EKNVSVMtMIFkESS
0 1
eIF2B-epsilon (human) EKNVSVMtMIFkESS T182-p
eIF2B-epsilon (mouse) EKNVSVMTMVFKESS T178
eIF2B-epsilon (rat) EKNVSVMTMVFKESS T177
eIF2B-epsilon (rabbit) EKNVSVMTMIFKESS T182
K186-ub
SVMtMIFkESSPSHP
0 1
eIF2B-epsilon (human) SVMtMIFkESSPSHP K186-ub
eIF2B-epsilon (mouse) SVMTMVFKESSPSHP K182
eIF2B-epsilon (rat) SVMTMVFKESSPSHP K181
eIF2B-epsilon (rabbit) SVMTMIFKESSPSHP K186
K217-ub
NRVLHFQkTQGLRRF
1 1
eIF2B-epsilon (human) NRVLHFQkTQGLRRF K217-ub
eIF2B-epsilon (mouse) NRVLHFQKTQGLRRF K213
eIF2B-epsilon (rat) NRILHFQkTQGLRHF K212-ub
eIF2B-epsilon (rabbit) NRILHFQKTQGLRRF K217
S229
RRFAFPLSLFQGSSD
0 1
eIF2B-epsilon (human) RRFAFPLSLFQGSSD S229
eIF2B-epsilon (mouse) RRFSFPLsLFQGSGD S225-p
eIF2B-epsilon (rat) RHFSFPLGLFQGSLD G224
eIF2B-epsilon (rabbit) RRFSFPLSLFQGSGA S229
Y319-p
DVIRRWVyPLTPEAN
0 3
eIF2B-epsilon (human) DVIRRWVyPLTPEAN Y319-p
eIF2B-epsilon (mouse) DVIRRWVYPLTPEVN Y315
eIF2B-epsilon (rat) DVIRRWVYPLtPEVN Y314
eIF2B-epsilon (rabbit) DVIRRWVYPLTPEAN Y319
T322
RRWVyPLTPEANFTD
1 0
eIF2B-epsilon (human) RRWVyPLTPEANFTD T322
eIF2B-epsilon (mouse) RRWVYPLTPEVNFTD T318
eIF2B-epsilon (rat) RRWVYPLtPEVNFTD T317-p
eIF2B-epsilon (rabbit) RRWVYPLTPEANFTD T322
K420-ub
LCDNAEVkERVTLKP
0 1
eIF2B-epsilon (human) LCDNAEVkERVTLKP K420-ub
eIF2B-epsilon (mouse) LCDRAEVKERVKLKP K416
eIF2B-epsilon (rat) LCDRAEVKERVILKP K415
eIF2B-epsilon (rabbit) LCDHAEVKEQVTLKP K420
S447-p
NITLPEGsVIsLHPP
0 1
eIF2B-epsilon (human) NITLPEGsVIsLHPP S447-p
eIF2B-epsilon (mouse) DITLPEGSVISLHPP S443
eIF2B-epsilon (rat) DIILPEGSVISLHPP S442
eIF2B-epsilon (rabbit) NITLPEGSVISLHPP S447
S450-p
LPEGsVIsLHPPDAE
0 1
eIF2B-epsilon (human) LPEGsVIsLHPPDAE S450-p
eIF2B-epsilon (mouse) LPEGSVISLHPPDAE S446
eIF2B-epsilon (rat) LPEGSVISLHPPDAE S445
eIF2B-epsilon (rabbit) LPEGSVISLHPPDAE S450
S466-p
DEDDGEFsDDsGADQ
Upstream
3 3
Phosphatases, in vitro:
  • PPP1CA (rabbit)
Treatment
  • amino_acids
eIF2B-epsilon (human) DEDDGEFsDDsGADQ S466-p
eIF2B-epsilon (mouse) DEDDGQFsDDsGADQ S462-p
eIF2B-epsilon (rat) DEDDGQFsDDsGADQ S461-p
eIF2B-epsilon (rabbit) DEDDGQFSDDSGVNQ S466
S469-p
DGEFsDDsGADQEKD
Upstream
2 3
Treatment
  • amino_acids
eIF2B-epsilon (human) DGEFsDDsGADQEKD S469-p
eIF2B-epsilon (mouse) DGQFsDDsGADQEKE S465-p
eIF2B-epsilon (rat) DGQFsDDsGADQEKE S464-p
eIF2B-epsilon (rabbit) DGQFSDDSGVNQAKE S469
K481-ub
EKDKVKMkGyNPAEV
0 3
eIF2B-epsilon (human) EKDKVKMkGyNPAEV K481-ub
eIF2B-epsilon (mouse) EKEKVKLkGYNPAEV K477-ub
eIF2B-epsilon (rat) EKEKVKLKGYNPAEV K476
eIF2B-epsilon (rabbit) AKEKAKLKGYNPAEV K481
Y483-p
DKVKMkGyNPAEVGA
0 1
eIF2B-epsilon (human) DKVKMkGyNPAEVGA Y483-p
eIF2B-epsilon (mouse) EKVKLkGYNPAEVGL Y479
eIF2B-epsilon (rat) EKVKLKGYNPAEVGP Y478
eIF2B-epsilon (rabbit) EKAKLKGYNPAEVGV Y483
K493-ub
AEVGAAGkGYLWKAA
Upstream
0 3
Treatment
  • MG132
eIF2B-epsilon (human) AEVGAAGkGYLWKAA K493-ub
eIF2B-epsilon (mouse) AEVGLEGQGYLWKAE Q489
eIF2B-epsilon (rat) AEVGPEGQGYLWKAE Q488
eIF2B-epsilon (rabbit) AEVGVAGKGYLWKAA K493
-
gap
1 0
eIF2B-epsilon (human) gap -
eIF2B-epsilon (mouse) KAEGVNSKEDEELRQ K501
eIF2B-epsilon (rat) KAEDVDEkEDEELRQ K500-ub
eIF2B-epsilon (rabbit) KAADMNTEKEEELRQ E505
S525-p
KINMEEEsEsEsEQs
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • translation, altered
Treatment
  • amino_acid_starvation
eIF2B-epsilon (human) KINMEEEsEsEsEQs S525-p
eIF2B-epsilon (mouse) MIKTEEESETESEGS S521
eIF2B-epsilon (rat) MINMEEESETESERs S520
eIF2B-epsilon (rabbit) TINEEEESETESERS S525
S527-p
NMEEEsEsEsEQsMD
0 1
eIF2B-epsilon (human) NMEEEsEsEsEQsMD S527-p
eIF2B-epsilon (mouse) KTEEESETESEGSVD T523
eIF2B-epsilon (rat) NMEEESETESERsVD T522
eIF2B-epsilon (rabbit) NEEEESETESERSMD T527
S529-p
EEEsEsEsEQsMDsE
0 1
eIF2B-epsilon (human) EEEsEsEsEQsMDsE S529-p
eIF2B-epsilon (mouse) EEESETESEGSVDPE S525
eIF2B-epsilon (rat) EEESETESERsVDPE S524
eIF2B-epsilon (rabbit) EEESETESERSMDSE S529
S532-p
sEsEsEQsMDsEEPD
0 2
eIF2B-epsilon (human) sEsEsEQsMDsEEPD S532-p
eIF2B-epsilon (mouse) SETESEGSVDPEELD S528
eIF2B-epsilon (rat) SETESERsVDPEELD S527-p
eIF2B-epsilon (rabbit) SETESERSMDSEELD S532
S535-p
EsEQsMDsEEPDsRG
0 1
eIF2B-epsilon (human) EsEQsMDsEEPDsRG S535-p
eIF2B-epsilon (mouse) ESEGSVDPEELDsRA P531
eIF2B-epsilon (rat) ESERsVDPEELDsRA P530
eIF2B-epsilon (rabbit) ESERSMDSEELDSRA S535
S540-p
MDsEEPDsRGGsPQM
Upstream
Downstream
9 3
Effects on Biological Processes:
  • signaling pathway regulation
  • translation, inhibited
Putative upstream phosphatases:
  • PPP2CA (human)
Treatment
  • 5-HT
  • amino_acids
  • BMP4
  • endothelin
  • lithium
  • SB216763
  • TGF-beta
eIF2B-epsilon (human) MDsEEPDsRGGsPQM S540-p
eIF2B-epsilon (mouse) VDPEELDsRAGsPQL S536-p
eIF2B-epsilon (rat) VDPEELDsRAGsPQL S535-p
eIF2B-epsilon (rabbit) MDSEELDSRAGSPQL S540
S544-p
EPDsRGGsPQMDDIK
Upstream
Downstream
5 85
Effects on Biological Processes:
  • signaling pathway regulation
  • translation, inhibited
Putative upstream phosphatases:
  • PPP2CA (human)
Treatment
  • amino_acids
  • MG132_withdrawal
eIF2B-epsilon (human) EPDsRGGsPQMDDIK S544-p
eIF2B-epsilon (mouse) ELDsRAGsPQLDDIR S540-p
eIF2B-epsilon (rat) ELDsRAGsPQLDDIR S539-p
eIF2B-epsilon (rabbit) ELDSRAGSPQLDDIK S544
K565-ub
LGTLQRGkEENISCD
0 1
eIF2B-epsilon (human) LGTLQRGkEENISCD K565-ub
eIF2B-epsilon (mouse) LGTLQRGREENISCE R561
eIF2B-epsilon (rat) LGTLQRGREENISCD R560
eIF2B-epsilon (rabbit) LGTLQRGKEESISCD K565
Y583-p
LEINSLKyAYNISLK
0 1
eIF2B-epsilon (human) LEINSLKyAYNISLK Y583-p
eIF2B-epsilon (mouse) LEINSLKHAYNISLK H579
eIF2B-epsilon (rat) LEINSLKYAYNISLK Y578
eIF2B-epsilon (rabbit) LEINSLKYAYNISLK Y583
S610-p
FPLQQMDsPLDSSRY
0 3
eIF2B-epsilon (human) FPLQQMDsPLDSSRY S610-p
eIF2B-epsilon (mouse) FPLQQVDGLLDPNRY G606
eIF2B-epsilon (rat) FPLQQVDGVLDPNRY G605
eIF2B-epsilon (rabbit) FPLQQMDSPLEANRY S610
K626
ALLLPLLKAWSPVFR
0 1
eIF2B-epsilon (human) ALLLPLLKAWSPVFR K626
eIF2B-epsilon (mouse) ALLLPLLkAWSPVLR K622-ub
eIF2B-epsilon (rat) ALLLPLLKAWSPVFR K621
eIF2B-epsilon (rabbit) ALLLPLLKAWSPVFR K626
K693-ub
SQRDTTDkGQQLRKN
0 1
eIF2B-epsilon (human) SQRDTTDkGQQLRKN K693-ub
eIF2B-epsilon (mouse) SQRDTTDEGQQLRKN E689
eIF2B-epsilon (rat) SQRDITDKGQQLRKN K688
eIF2B-epsilon (rabbit) GQRDVTDKGRQLRKN K693
S717-p
LKEAEEEssEDD___
Upstream
3 12
Treatment
  • amino_acids
eIF2B-epsilon (human) LKEAEEEssEDD___ S717-p
eIF2B-epsilon (mouse) LREAEEEssEDD___ S713-p
eIF2B-epsilon (rat) LREAEEEssDDD___ S712-p
eIF2B-epsilon (rabbit) LKEAEEEssEDD___ S717-p
S718-p
KEAEEEssEDD____
Upstream
3 11
Treatment
  • amino_acids
  • MLN8054
eIF2B-epsilon (human) KEAEEEssEDD____ S718-p
eIF2B-epsilon (mouse) REAEEEssEDD____ S714-p
eIF2B-epsilon (rat) REAEEEssDDD____ S713-p
eIF2B-epsilon (rabbit) KEAEEEssEDD____ S718-p