Other Species / Isoforms
  RFA2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MWNsGFEsyGs
Upstream
Downstream
35 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, induced
  • cell cycle regulation
  • cell growth, altered
  • transcription, altered
Putative in vivo kinases:
  • DNAPK (human)
Putative upstream phosphatases:
  • PPP4C (human)
Regulatory protein:
  • ATM (human)
  • ATR (human)
  • BAT1 (human)
  • BRCA1 (human)
  • CDC5L (human)
  • CDK5 (human)
  • Chk1 (human)
  • CtIP (human)
  • DNAPK (human)
  • FAM44A (human)
  • FANCD2 (human)
  • FOXM1 (human)
  • MCPH1 (human)
  • NBS1 (human)
  • NONO (human)
  • p21Cip1 (human)
  • p53 (human)
  • PARG (human)
  • PIAS1 (human)
  • PIAS4 (human)
  • POLH (human)
  • PRPF19 (human)
  • PRPF3 (human)
  • SIRT6 (human)
  • TELO2 (human)
  • TOPBP1 (human)
Treatment
  • 4-nitroquinoline_1-oxide
  • adriamycin
  • aphidicolin
  • AZ20
  • caffeine
  • camptothecin
  • carboplatin
  • CGK733
  • cisplatin
  • CPT
  • etoposide
  • gemcitabine
  • HAMNO
  • hydroxyurea
  • ionizing_radiation
  • KU-55933
  • mirin
  • miRNA
  • mitomycin_C
  • MK-8776
  • MMS
  • NU7026
  • NU7441
  • olaparib
  • oxaliplatin
  • prexasertib
  • seliciclib
  • siRNA
  • UCN-01
  • UV
  • VE-821
RFA2 (human) ____MWNsGFEsyGs S4-p
RFA2 iso3 (human) LILLFKTGGFESYGS G92
RFA2 (mouse) ____MWNsGFESFtS S4-p
RFA2 (rat) ____MWNSGFESFSS S4
S8-p
MWNsGFEsyGsssyG
Upstream
Downstream
36 2
RFA2 (human)
S8-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, induced
  • cell cycle regulation
  • cell growth, altered
  • transcription, altered
Putative in vivo kinases:
  • DNAPK (human)
Putative upstream phosphatases:
  • PPP4C (human)
Regulatory protein:
  • ATM (human)
  • ATR (human)
  • BAT1 (human)
  • BRCA1 (human)
  • CDC5L (human)
  • CDK5 (human)
  • Chk1 (human)
  • CtIP (human)
  • DNAPK (human)
  • FAM44A (human)
  • FANCD2 (human)
  • FOXM1 (human)
  • MCPH1 (human)
  • NBS1 (human)
  • NONO (human)
  • p21Cip1 (human)
  • p53 (human)
  • PARG (human)
  • PIAS1 (human)
  • PIAS4 (human)
  • POLH (human)
  • PPP4R2 (human)
  • PRPF19 (human)
  • PRPF3 (human)
  • SIRT6 (human)
  • TELO2 (human)
  • TOPBP1 (human)
Treatment
  • 4-nitroquinoline_1-oxide
  • adriamycin
  • aphidicolin
  • AZ20
  • caffeine
  • camptothecin
  • carboplatin
  • CGK733
  • cisplatin
  • CPT
  • etoposide
  • gemcitabine
  • HAMNO
  • hydroxyurea
  • ionizing_radiation
  • KU-55933
  • mirin
  • miRNA
  • mitomycin_C
  • MK-8776
  • MMS
  • NU7026
  • NU7441
  • olaparib
  • oxaliplatin
  • prexasertib
  • seliciclib
  • siRNA
  • UCN-01
  • UV
  • VE-821
RFA2 (human) MWNsGFEsyGsssyG S8-p
RFA2 iso3 (human) FKTGGFESYGSSSYG S96
RFA2 (mouse) MWNsGFESFtSsTyG S8
RFA2 (rat) MWNSGFESFSSSSYG S8
Y9-p
WNsGFEsyGsssyGG
0 1
RFA2 (human) WNsGFEsyGsssyGG Y9-p
RFA2 iso3 (human) KTGGFESYGSSSYGG Y97
RFA2 (mouse) WNsGFESFtSsTyGG F9
RFA2 (rat) WNSGFESFSSSSYGA F9
G10
NsGFEsyGsssyGGA
0 1
RFA2 (human) NsGFEsyGsssyGGA G10
RFA2 iso3 (human) TGGFESYGSSSYGGA G98
RFA2 (mouse) NsGFESFtSsTyGGR T10-p
RFA2 (rat) NSGFESFSSSSYGAA S10
S11-p
sGFEsyGsssyGGAG
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell growth, altered
Treatment
  • UV
RFA2 (human) sGFEsyGsssyGGAG S11-p
RFA2 iso3 (human) GGFESYGSSSYGGAG S99
RFA2 (mouse) sGFESFtSsTyGGRG S11
RFA2 (rat) SGFESFSSSSYGAAG S11
S12-p
GFEsyGsssyGGAGG
Upstream
Downstream
3 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell growth, altered
Treatment
  • UV
RFA2 (human) GFEsyGsssyGGAGG S12-p
RFA2 iso3 (human) GFESYGSSSYGGAGG S100
RFA2 (mouse) GFESFtSsTyGGRGG S12-p
RFA2 (rat) GFESFSSSSYGAAGG S12
S13-p
FEsyGsssyGGAGGY
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell growth, altered
Treatment
  • UV
RFA2 (human) FEsyGsssyGGAGGY S13-p
RFA2 iso3 (human) FESYGSSSYGGAGGY S101
RFA2 (mouse) FESFtSsTyGGRGGY T13
RFA2 (rat) FESFSSSSYGAAGGY S13
Y14-p
EsyGsssyGGAGGYt
0 2
RFA2 (human) EsyGsssyGGAGGYt Y14-p
RFA2 iso3 (human) ESYGSSSYGGAGGYT Y102
RFA2 (mouse) ESFtSsTyGGRGGYT Y14-p
RFA2 (rat) ESFSSSSYGAAGGYT Y14
T21-p
yGGAGGYtQsPGGFG
Upstream
Downstream
19 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, altered
  • cell cycle regulation
  • cell growth, altered
  • transcription, altered
Kinase, in vitro:
  • ATM (human)
  • ATR (human)
  • DNAPK (human)
Putative in vivo kinases:
  • ATM (human)
  • DNAPK (human)
Putative upstream phosphatases:
  • PPP2CA (human)
  • PPP4C (human)
Regulatory protein:
  • ATM (human)
  • ATR (human)
  • BAT1 (human)
  • CDC5L (human)
  • CLK2 (human)
  • CtIP (human)
  • FAAP24 (human)
  • FANCM (human)
  • FBXO44 (human)
  • p21Cip1 (human)
  • p53 (human)
  • PRPF19 (human)
  • PRPF3 (human)
  • SUV39H1 (human)
  • TOPBP1 (human)
Treatment
  • adriamycin
  • aphidicolin
  • AZ20
  • caffeine
  • camptothecin
  • CPT
  • Et743
  • etoposide
  • hydroxyurea
  • ionizing_radiation
  • lurbinectedin
  • okadaic_acid
  • olaparib
  • release from HU
  • release_from_UV
  • seliciclib
  • siRNA
  • t-BH
  • UV
  • wortmannin
RFA2 (human) yGGAGGYtQsPGGFG T21-p
RFA2 iso3 (human) YGGAGGYTQSPGGFG T109
RFA2 (mouse) yGGRGGYTQSPGGFG T21
RFA2 (rat) YGAAGGYTQSPGGFG T21
S23-p
GAGGYtQsPGGFGsP
Upstream
Downstream
7 3
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
Kinase, in vitro:
  • CDK1 (human)
  • CDK2 (human)
  • CDK5 (human)
Putative in vivo kinases:
  • ATM (human)
  • DNAPK (human)
Regulatory protein:
  • PPP4R2 (human)
Treatment
  • CPT
  • hydroxyurea
  • ionizing_radiation
  • KU-55933
  • nocodazole
  • NU7441
  • seliciclib
  • UV
  • wortmannin
RFA2 (human) GAGGYtQsPGGFGsP S23-p
RFA2 iso3 (human) GAGGYTQSPGGFGSP S111
RFA2 (mouse) GRGGYTQSPGGFGsP S23
RFA2 (rat) AAGGYTQSPGGFGSP S23
S29-p
QsPGGFGsPAPsQAE
Upstream
Downstream
11 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • transcription, altered
Kinase, in vitro:
  • CDK1 (human)
  • CDK2 (human)
  • CDK5 (human)
Putative in vivo kinases:
  • ATM (human)
  • DNAPK (human)
Regulatory protein:
  • APC (human)
  • CDK2 (human)
  • CDK5 (human)
  • p21Cip1 (human)
  • p53 (human)
  • PPP4R2 (human)
Treatment
  • camptothecin
  • CPT
  • hydroxyurea
  • ionizing_radiation
  • KU-55933
  • nocodazole
  • NU7441
  • seliciclib
  • U0126
  • UV
  • wortmannin
RFA2 (human) QsPGGFGsPAPsQAE S29-p
RFA2 iso3 (human) QSPGGFGSPAPSQAE S117
RFA2 (mouse) QSPGGFGsPtPsQAE S29-p
RFA2 (rat) QSPGGFGSPTPSQAE S29
A31
PGGFGsPAPsQAEKK
0 1
RFA2 (human) PGGFGsPAPsQAEKK A31
RFA2 iso3 (human) PGGFGSPAPSQAEKK A119
RFA2 (mouse) PGGFGsPtPsQAEKK T31-p
RFA2 (rat) PGGFGSPTPSQAEKK T31
S33-p
GFGsPAPsQAEKKSR
Upstream
Downstream
33 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • DNA repair, induced
  • DNA repair, inhibited
  • apoptosis, altered
  • cell cycle regulation
  • cell growth, altered
  • cell growth, induced
Kinase, in vitro:
  • ATR (human)
  • CDK1 (human)
  • CDK2 (human)
  • CDK5 (human)
  • DNAPK (human)
Putative in vivo kinases:
  • ATR (human)
Putative upstream phosphatases:
  • PPP2CA (human)
  • PPP4C (human)
Regulatory protein:
  • APC (human)
  • ARID1A (human)
  • ATR (human)
  • CDC5L (human)
  • CDK5 (human)
  • CtIP (human)
  • DNAPK (human)
  • FANCD2 (human)
  • MCPH1 (human)
  • NBS1 (human)
  • PPP4R2 (human)
  • PRPF19 (human)
  • PRPF3 (human)
  • RAD17 (human)
  • RNASEH1 (human)
  • SSB1 (human)
  • TOP2A (human)
  • TOPBP1 (human)
Treatment
  • AP20187
  • aphidicolin
  • AZ20
  • caffeine
  • camptothecin
  • CGK733
  • cisplatin
  • CPT
  • ETAA1
  • etoposide
  • g_DNA
  • HAMNO
  • hydroxyurea
  • KU-55933
  • lncRNAs
  • nocodazole
  • NU7026
  • NU7441
  • okadaic_acid
  • olaparib
  • oxaliplatin
  • prexasertib
  • release from HU
  • release_from_UV
  • seliciclib
  • siRNA
  • UV
  • VE-821
RFA2 (human) GFGsPAPsQAEKKSR S33-p
RFA2 iso3 (human) GFGSPAPSQAEKKSR S121
RFA2 (mouse) GFGsPtPsQAEKKsR S33-p
RFA2 (rat) GFGSPTPSQAEKKSR S33
S39
PsQAEKKSRARAQHI
0 1
RFA2 (human) PsQAEKKSRARAQHI S39
RFA2 iso3 (human) PSQAEKKSRARAQHI S127
RFA2 (mouse) PsQAEKKsRVRAQHI S39-p
RFA2 (rat) PSQAEKKSRARAQHI S39
S52-p
HIVPCTIsQLLSATL
Upstream
1 0
Kinase, in vitro:
  • ATR (human)
RFA2 (human) HIVPCTIsQLLSATL S52-p
RFA2 iso3 (human) HIVPCTISQLLSATL S140
RFA2 (mouse) HIVPCTISQLLSATL S52
RFA2 (rat) HIVPCTISQLLSATL S52
S72-p
RIGNVEIsQVTIVGI
Upstream
1 0
Kinase, in vitro:
  • ATR (human)
RFA2 (human) RIGNVEIsQVTIVGI S72-p
RFA2 iso3 (human) RIGNVEISQVTIVGI S160
RFA2 (mouse) RIGDVEISQVTIVGI S72
RFA2 (rat) KIGDVEISQVTIVGI S72
K85-ub
GIIRHAEkAPtNIVY
0 6
RFA2 (human) GIIRHAEkAPtNIVY K85-ub
RFA2 iso3 (human) GIIRHAEKAPTNIVY K173
RFA2 (mouse) GIIRHAEKAPTNIVY K85
RFA2 (rat) GIIRHAEKAPTNIVY K85
T88-p
RHAEkAPtNIVYkID
0 1
RFA2 (human) RHAEkAPtNIVYkID T88-p
RFA2 iso3 (human) RHAEKAPTNIVYKID T176
RFA2 (mouse) RHAEKAPTNIVYKID T88
RFA2 (rat) RHAEKAPTNIVYKID T88
K93-ub
APtNIVYkIDDMTAA
0 3
RFA2 (human) APtNIVYkIDDMTAA K93-ub
RFA2 iso3 (human) APTNIVYKIDDMTAA K181
RFA2 (mouse) APTNIVYKIDDMTAP K93
RFA2 (rat) APTNIVYKIDDMTAA K93
R105-m1
TAAPMDVrQWVDTDD
0 1
RFA2 (human) TAAPMDVrQWVDTDD R105-m1
RFA2 iso3 (human) TAAPMDVRQWVDTDD R193
RFA2 (mouse) TAPPMDVRQWVDTDD R105
RFA2 (rat) TAAPMDVRQWVDTDD R105
K127-ub
VPPETYVkVAGHLrS
0 7
RFA2 (human) VPPETYVkVAGHLrS K127-ub
RFA2 iso3 (human) VPPETYVKVAGHLRS K215
RFA2 (mouse) VPPETYVKVAGHLRS K127
RFA2 (rat) VPPETYVKVAGHLRS K127
R133-m1
VkVAGHLrSFQNKkS
0 1
RFA2 (human) VkVAGHLrSFQNKkS R133-m1
RFA2 iso3 (human) VKVAGHLRSFQNKKS R221
RFA2 (mouse) VKVAGHLRSFQNKKS R133
RFA2 (rat) VKVAGHLRSFQNKKS R133
K139-ub
LrSFQNKkSLVAFKI
0 1
RFA2 (human) LrSFQNKkSLVAFKI K139-ub
RFA2 iso3 (human) LRSFQNKKSLVAFKI K227
RFA2 (mouse) LRSFQNKKSLVAFKI K139
RFA2 (rat) LRSFQNKKSLVAFKI K139
K171-ub
NAHMVLSkANsQPSA
0 1
RFA2 (human) NAHMVLSkANsQPSA K171-ub
RFA2 iso3 (human) NAHMVLSKANSQPSA K259
RFA2 (mouse) NSHMMLSKPNSQASA K171
RFA2 (rat) NSHLMLSKANSQASV K171
S174-p
MVLSkANsQPSAGRA
Upstream
1 0
Kinase, in vitro:
  • ATR (human)
RFA2 (human) MVLSkANsQPSAGRA S174-p
RFA2 iso3 (human) MVLSKANSQPSAGRA S262
RFA2 (mouse) MMLSKPNSQASAGRP S174
RFA2 (rat) LMLSKANSQASVGRP S174
K231-ub
GLNFQDLkNQLkHMs
0 2
RFA2 (human) GLNFQDLkNQLkHMs K231-ub
RFA2 iso3 (human) GLNFQDLKNQLKHMS K319
RFA2 (mouse) GLNFQDLRsQLQHMP R231
RFA2 (rat) GLNFQDLRSQLQHMP R231
K231-ac
GLNFQDLkNQLkHMs
0 1
RFA2 (human) GLNFQDLkNQLkHMs K231-ac
RFA2 iso3 (human) GLNFQDLKNQLKHMS K319
RFA2 (mouse) GLNFQDLRsQLQHMP R231
RFA2 (rat) GLNFQDLRSQLQHMP R231
N232
LNFQDLkNQLkHMsV
0 1
RFA2 (human) LNFQDLkNQLkHMsV N232
RFA2 iso3 (human) LNFQDLKNQLKHMSV N320
RFA2 (mouse) LNFQDLRsQLQHMPV S232-p
RFA2 (rat) LNFQDLRSQLQHMPV S232
K235-ub
QDLkNQLkHMsVsSI
0 4
RFA2 (human) QDLkNQLkHMsVsSI K235-ub
RFA2 iso3 (human) QDLKNQLKHMSVSSI K323
RFA2 (mouse) QDLRsQLQHMPVPsI Q235
RFA2 (rat) QDLRSQLQHMPVASI Q235
S238-p
kNQLkHMsVsSIkQA
0 9
RFA2 (human) kNQLkHMsVsSIkQA S238-p
RFA2 iso3 (human) KNQLKHMSVSSIKQA S326
RFA2 (mouse) RsQLQHMPVPsIKQA P238
RFA2 (rat) RSQLQHMPVASIKQA P238
S240-p
QLkHMsVsSIkQAVD
0 2
RFA2 (human) QLkHMsVsSIkQAVD S240-p
RFA2 iso3 (human) QLKHMSVSSIKQAVD S328
RFA2 (mouse) QLQHMPVPsIKQAVD P240
RFA2 (rat) QLQHMPVASIKQAVD A240
S241
LkHMsVsSIkQAVDF
0 1
RFA2 (human) LkHMsVsSIkQAVDF S241
RFA2 iso3 (human) LKHMSVSSIKQAVDF S329
RFA2 (mouse) LQHMPVPsIKQAVDF S241-p
RFA2 (rat) LQHMPVASIKQAVDF S241
K243-ub
HMsVsSIkQAVDFLS
0 1
RFA2 (human) HMsVsSIkQAVDFLS K243-ub
RFA2 iso3 (human) HMSVSSIKQAVDFLS K331
RFA2 (mouse) HMPVPsIKQAVDFLC K243
RFA2 (rat) HMPVASIKQAVDFLC K243