Other Species / Isoforms
  NPM1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MEDsMDMDMsP
Upstream
Downstream
6 30
NPM1 (human)
S4-p
NPM1 iso2 (human)
S4-p
NPM1 (mouse)
S4-p
NPM1 (rat)
S4-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
  • cytoskeletal reorganization
Kinase, in vitro:
  • PLK1 (human)
  • PLK2 (human)
  • PLK3 (human)
view more >
Putative in vivo kinases:
  • PLK1 (human)
  • PLK2 (human)
Treatment
  • aphidicolin
  • BI2536
  • bleomycin
  • DRB
  • EGF
  • hydroxyurea
  • ionizing_radiation
  • LY294002
  • nocodazole
  • olomoucine
  • PD98059
  • RITA
  • SB203580
  • siRNA
view more >
NPM1 (human) ____MEDsMDMDMsP S4-p
NPM1 iso2 (human) ____MEDSMDMDMSP S4
NPM1 iso3 (human) ____MEDSMDMDMSP S4
NPM1 (mouse) ____MEDsMDMDMsP S4-p
NPM1 (rat) ____MEDsMDMDMsP S4-p
NPM1 iso2 (rat) ____MEDSMDMDMSP S4
S10-p
DsMDMDMsPLRPQNy
Upstream
Downstream
2 30
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
Treatment
  • bleomycin
  • nocodazole
NPM1 (human) DsMDMDMsPLRPQNy S10-p
NPM1 iso2 (human) DSMDMDMSPLRPQNY S10
NPM1 iso3 (human) DSMDMDMSPLRPQNY S10
NPM1 (mouse) DsMDMDMsPLRPQNy S10-p
NPM1 (rat) DsMDMDMsPLRPQNY S10-p
NPM1 iso2 (rat) DSMDMDMSPLRPQNY S10
Y17-p
sPLRPQNyLFGCELk
Upstream
0 3
Treatment
  • nocodazole
NPM1 (human) sPLRPQNyLFGCELk Y17-p
NPM1 iso2 (human) SPLRPQNYLFGCELK Y17
NPM1 iso3 (human) SPLRPQNYLFGCELK Y17
NPM1 (mouse) sPLRPQNyLFGCELK Y17-p
NPM1 (rat) sPLRPQNYLFGCELK Y17
NPM1 iso2 (rat) SPLRPQNYLFGCELK Y17
K24-ac
yLFGCELkADkDyHF
0 1
NPM1 (human) yLFGCELkADkDyHF K24-ac
NPM1 iso2 (human) YLFGCELKADKDyHF K24
NPM1 iso3 (human) YLFGCELKADKDYHF K24
NPM1 (mouse) yLFGCELKADkDyHF K24
NPM1 (rat) YLFGCELKADkDYHF K24
NPM1 iso2 (rat) YLFGCELKADKDYHF K24
K27-ub
GCELkADkDyHFkVD
0 11
NPM1 (human) GCELkADkDyHFkVD K27-ub
NPM1 iso2 (human) GCELKADKDyHFKVD K27
NPM1 iso3 (human) GCELKADKDYHFKVD K27
NPM1 (mouse) GCELKADkDyHFkVD K27-ub
NPM1 (rat) GCELKADKDYHFkVD K27
NPM1 iso2 (rat) GCELKADKDYHFKVD K27
K27-ac
GCELkADkDyHFkVD
Upstream
1 5
Treatment
  • UV
NPM1 (human) GCELkADkDyHFkVD K27-ac
NPM1 iso2 (human) GCELKADKDyHFKVD K27
NPM1 iso3 (human) GCELKADKDYHFKVD K27
NPM1 (mouse) GCELKADkDyHFkVD K27-ac
NPM1 (rat) GCELKADkDYHFkVD K27-ac
NPM1 iso2 (rat) GCELKADKDYHFKVD K27
K27-sc
GCELkADkDyHFkVD
0 1
NPM1 (human) GCELkADkDyHFkVD K27-sc
NPM1 iso2 (human) GCELKADKDyHFKVD K27
NPM1 iso3 (human) GCELKADKDYHFKVD K27
NPM1 (mouse) GCELKADKDyHFkVD K27
NPM1 (rat) GCELKADKDYHFkVD K27
NPM1 iso2 (rat) GCELKADKDYHFKVD K27
K27-sm
GCELkADkDyHFkVD
0 2
NPM1 (human) GCELkADkDyHFkVD K27-sm
NPM1 iso2 (human) GCELKADKDyHFKVD K27
NPM1 iso3 (human) GCELKADKDYHFKVD K27
NPM1 (mouse) GCELKADKDyHFkVD K27
NPM1 (rat) GCELKADKDYHFkVD K27
NPM1 iso2 (rat) GCELKADKDYHFKVD K27
Y29-p
ELkADkDyHFkVDND
0 44
NPM1 (human) ELkADkDyHFkVDND Y29-p
NPM1 iso2 (human) ELKADKDyHFKVDND Y29-p
NPM1 iso3 (human) ELKADKDYHFKVDND Y29
NPM1 (mouse) ELKADkDyHFkVDND Y29-p
NPM1 (rat) ELKADkDYHFkVDND Y29
NPM1 iso2 (rat) ELKADKDYHFKVDND Y29
K32-ac
ADkDyHFkVDNDENE
Upstream
0 22
Treatment
  • vorinostat
NPM1 (human) ADkDyHFkVDNDENE K32-ac
NPM1 iso2 (human) ADKDyHFKVDNDENE K32
NPM1 iso3 (human) ADKDYHFKVDNDENE K32
NPM1 (mouse) ADkDyHFkVDNDENE K32-ac
NPM1 (rat) ADkDYHFkVDNDENE K32-ac
NPM1 iso2 (rat) ADKDYHFKVDNDENE K32
K32-ub
ADkDyHFkVDNDENE
0 17
NPM1 (human) ADkDyHFkVDNDENE K32-ub
NPM1 iso2 (human) ADKDyHFKVDNDENE K32
NPM1 iso3 (human) ADKDYHFKVDNDENE K32
NPM1 (mouse) ADkDyHFkVDNDENE K32-ub
NPM1 (rat) ADkDYHFKVDNDENE K32
NPM1 iso2 (rat) ADKDYHFKVDNDENE K32
K32-sc
ADkDyHFkVDNDENE
0 1
NPM1 (human) ADkDyHFkVDNDENE K32-sc
NPM1 iso2 (human) ADKDyHFKVDNDENE K32
NPM1 iso3 (human) ADKDYHFKVDNDENE K32
NPM1 (mouse) ADkDyHFKVDNDENE K32
NPM1 (rat) ADkDYHFKVDNDENE K32
NPM1 iso2 (rat) ADKDYHFKVDNDENE K32
K32-sm
ADkDyHFkVDNDENE
0 4
NPM1 (human) ADkDyHFkVDNDENE K32-sm
NPM1 iso2 (human) ADKDyHFKVDNDENE K32
NPM1 iso3 (human) ADKDYHFKVDNDENE K32
NPM1 (mouse) ADkDyHFKVDNDENE K32
NPM1 (rat) ADkDYHFKVDNDENE K32
NPM1 iso2 (rat) ADKDYHFKVDNDENE K32
S43-p
DENEHQLsLrTVsLG
0 6
NPM1 (human) DENEHQLsLrTVsLG S43-p
NPM1 iso2 (human) DENEHQLSLRTVSLG S43
NPM1 iso3 (human) DENEHQLSLRTVSLG S43
NPM1 (mouse) DENEHQLsLRTVsLG S43-p
NPM1 (rat) DENEHQLSLRTVSLG S43
NPM1 iso2 (rat) DENEHQLSLRTVSLG S43
R45-m1
NEHQLsLrTVsLGAG
0 1
NPM1 (human) NEHQLsLrTVsLGAG R45-m1
NPM1 iso2 (human) NEHQLSLRTVSLGAG R45
NPM1 iso3 (human) NEHQLSLRTVSLGAG R45
NPM1 (mouse) NEHQLsLRTVsLGAG R45
NPM1 (rat) NEHQLSLRTVSLGAG R45
NPM1 iso2 (rat) NEHQLSLRTVSLGAG R45
S48-p
QLsLrTVsLGAGAkD
Upstream
Downstream
2 2
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein degradation
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • Akt1 (human)
Putative in vivo kinases:
  • Akt1 (human)
Treatment
  • EGF
  • MK-2206
  • PI-103
  • siRNA
view more >
NPM1 (human) QLsLrTVsLGAGAkD S48-p
NPM1 iso2 (human) QLSLRTVSLGAGAKD S48
NPM1 iso3 (human) QLSLRTVSLGAGAKD S48
NPM1 (mouse) QLsLRTVsLGAGAkD S48-p
NPM1 (rat) QLSLRTVSLGAGAkD S48
NPM1 iso2 (rat) QLSLRTVSLGAGAKD S48
K54-ub
VsLGAGAkDELHIVE
0 21
NPM1 (human) VsLGAGAkDELHIVE K54-ub
NPM1 iso2 (human) VSLGAGAKDELHIVE K54
NPM1 iso3 (human) VSLGAGAKDELHIVE K54
NPM1 (mouse) VsLGAGAkDELHIVE K54-ub
NPM1 (rat) VSLGAGAKDELHIVE K54
NPM1 iso2 (rat) VSLGAGAKDELHIVE K54
K54-ac
VsLGAGAkDELHIVE
Upstream
1 6
Treatment
  • UV
NPM1 (human) VsLGAGAkDELHIVE K54-ac
NPM1 iso2 (human) VSLGAGAKDELHIVE K54
NPM1 iso3 (human) VSLGAGAKDELHIVE K54
NPM1 (mouse) VsLGAGAkDELHIVE K54-ac
NPM1 (rat) VSLGAGAkDELHIVE K54-ac
NPM1 iso2 (rat) VSLGAGAKDELHIVE K54
Y67-p
VEAEAMNyEGsPIKV
Upstream
Downstream
1 23
Effects on Modified Protein
  • protein conformation
Treatment
  • metastatic potential
  • rapamycin
NPM1 (human) VEAEAMNyEGsPIKV Y67-p
NPM1 iso2 (human) VEAEAMNYEGSPIKV Y67
NPM1 iso3 (human) VEAEAMNYEGSPIKV Y67
NPM1 (mouse) VEAEAMNyEGsPIKV Y67-p
NPM1 (rat) VEAEAMNyEGsPIKV Y67-p
NPM1 iso2 (rat) VEAEAMNYEGSPIKV Y67
S70-p
EAMNyEGsPIKVtLA
Upstream
Downstream
3 117
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK1 (human)
  • CDK2 (human)
Putative in vivo kinases:
  • NEK2 (human)
Putative upstream phosphatases:
  • PPP1CA (human)
Regulatory protein:
  • PRP4 (human)
Treatment
  • adriamycin
  • antibody
  • BI2536
  • ischemia
  • KU-55933
  • metastatic potential
  • metformin
  • rapamycin
  • siRNA
  • Torin1
view more >
NPM1 (human) EAMNyEGsPIKVtLA S70-p
NPM1 iso2 (human) EAMNYEGSPIKVTLA S70
NPM1 iso3 (human) EAMNYEGSPIKVTLA S70
NPM1 (mouse) EAMNyEGsPIKVtLA S70-p
NPM1 (rat) EAMNyEGsPIKVTLA S70-p
NPM1 iso2 (rat) EAMNYEGSPIKVTLA S70
T75-p
EGsPIKVtLAtLkMs
Upstream
0 7
Treatment
  • rapamycin
NPM1 (human) EGsPIKVtLAtLkMs T75-p
NPM1 iso2 (human) EGSPIKVTLATLKMS T75
NPM1 iso3 (human) EGSPIKVTLATLKMS T75
NPM1 (mouse) EGsPIKVtLATLKMs T75-p
NPM1 (rat) EGsPIKVTLATLKMS T75
NPM1 iso2 (rat) EGSPIKVTLATLKMS T75
T78-p
PIKVtLAtLkMsVQP
Upstream
0 5
Treatment
  • rapamycin
NPM1 (human) PIKVtLAtLkMsVQP T78-p
NPM1 iso2 (human) PIKVTLATLKMSVQP T78
NPM1 iso3 (human) PIKVTLATLKMSVQP T78
NPM1 (mouse) PIKVtLATLKMsVQP T78
NPM1 (rat) PIKVTLATLKMSVQP T78
NPM1 iso2 (rat) PIKVTLATLKMSVQP T78
K80-ub
KVtLAtLkMsVQPtV
0 4
NPM1 (human) KVtLAtLkMsVQPtV K80-ub
NPM1 iso2 (human) KVTLATLKMSVQPTV K80
NPM1 iso3 (human) KVTLATLKMSVQPTV K80
NPM1 (mouse) KVtLATLKMsVQPTV K80
NPM1 (rat) KVTLATLKMSVQPTV K80
NPM1 iso2 (rat) KVTLATLKMSVQPTV K80
S82-p
tLAtLkMsVQPtVsL
0 3
NPM1 (human) tLAtLkMsVQPtVsL S82-p
NPM1 iso2 (human) TLATLKMSVQPTVSL S82
NPM1 iso3 (human) TLATLKMSVQPTVSL S82
NPM1 (mouse) tLATLKMsVQPTVsL S82-p
NPM1 (rat) TLATLKMSVQPTVSL S82
NPM1 iso2 (rat) TLATLKMSVQPTVSL S82
T86-p
LkMsVQPtVsLGGFE
0 3
NPM1 (human) LkMsVQPtVsLGGFE T86-p
NPM1 iso2 (human) LKMSVQPTVSLGGFE T86
NPM1 iso3 (human) LKMSVQPTVSLGGFE T86
NPM1 (mouse) LKMsVQPTVsLGGFE T86
NPM1 (rat) LKMSVQPTVSLGGFE T86
NPM1 iso2 (rat) LKMSVQPTVSLGGFE T86
S88-p
MsVQPtVsLGGFEIt
Upstream
Downstream
2 11
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Putative in vivo kinases:
  • NEK2 (human)
Putative upstream phosphatases:
  • PPP1CA (human)
Treatment
  • adriamycin
  • bleomycin
  • KU-55933
  • siRNA
view more >
NPM1 (human) MsVQPtVsLGGFEIt S88-p
NPM1 iso2 (human) MSVQPTVSLGGFEIt S88
NPM1 iso3 (human) MSVQPTVSLGGFEIT S88
NPM1 (mouse) MsVQPTVsLGGFEIt S88-p
NPM1 (rat) MSVQPTVSLGGFEIT S88
NPM1 iso2 (rat) MSVQPTVSLGGFEIT S88
T95-p
sLGGFEItPPVVLrL
Upstream
2 36
NPM1 (human)
T95-p
NPM1 iso2 (human)
T95-p
NPM1 (mouse)
T95-p
NPM1 (rat)
T95-p
Treatment
  • rapamycin
NPM1 (human) sLGGFEItPPVVLrL T95-p
NPM1 iso2 (human) SLGGFEItPPVVLRL T95-p
NPM1 iso3 (human) SLGGFEITPPVVLRL T95
NPM1 (mouse) sLGGFEItPPVVLRL T95-p
NPM1 (rat) SLGGFEITPPVVLRL T95
NPM1 iso2 (rat) SLGGFEITPPVVLRL T95
R101-m1
ItPPVVLrLKCGsGP
0 1
NPM1 (human) ItPPVVLrLKCGsGP R101-m1
NPM1 iso2 (human) ItPPVVLRLKCGSGP R101
NPM1 iso3 (human) ITPPVVLRLKCGSGP R101
NPM1 (mouse) ItPPVVLRLKCGsGP R101
NPM1 (rat) ITPPVVLRLKCGsGP R101
NPM1 iso2 (rat) ITPPVVLRLKCGSGP R101
S106-p
VLrLKCGsGPVHIsG
1 16
NPM1 (human) VLrLKCGsGPVHIsG S106-p
NPM1 iso2 (human) VLRLKCGSGPVHISG S106
NPM1 iso3 (human) VLRLKCGSGPVHISG S106
NPM1 (mouse) VLRLKCGsGPVHIsG S106-p
NPM1 (rat) VLRLKCGsGPVHISG S106-p
NPM1 iso2 (rat) VLRLKCGSGPVHISG S106
S112-p
GsGPVHIsGQHLVAV
0 9
NPM1 (human) GsGPVHIsGQHLVAV S112-p
NPM1 iso2 (human) GSGPVHISGQHLVAV S112
NPM1 iso3 (human) GSGPVHISGQHLVAV S112
NPM1 (mouse) GsGPVHIsGQHLVAV S112-p
NPM1 (rat) GsGPVHISGQHLVAV S112
NPM1 iso2 (rat) GSGPVHISGQHLVAV S112
S125-p
AVEEDAEsEDEEEED
Upstream
Downstream
11 647
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • cell motility, induced
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • ATR (human)
  • AurA (human)
  • AurB (human)
  • CK2A1 (human)
view more >
Putative in vivo kinases:
  • AurA (human)
  • AurB (human)
Regulatory protein:
  • AurA (human)
  • CK2A1 (human)
  • PPP1CA (human)
  • PRP4 (human)
view more >
Treatment
  • 1E7-03
  • AZD1152
  • calyculin_A
  • cell cycle regulated
  • ionizing_radiation
  • MG132_withdrawal
  • MLN8237
  • nocodazole
  • okadaic_acid
  • siRNA
  • ZM447439
view more >
NPM1 (human) AVEEDAEsEDEEEED S125-p
NPM1 iso2 (human) AVEEDAESEDEEEED S125
NPM1 iso3 (human) AVEEDAESEDEEEED S125
NPM1 (mouse) AVEEDAEsEDEDEED S125-p
NPM1 (rat) AVEEDAEsEDEDEED S125-p
NPM1 iso2 (rat) AVEEDAESEDEDEED S125
K134-sm
DEEEEDVkLLsIsGk
0 1
NPM1 (human) DEEEEDVkLLsIsGk K134-sm
NPM1 iso2 (human) DEEEEDVKLLsISGk K134
NPM1 iso3 (human) DEEEEDVKLLSISGK K134
NPM1 (mouse) DEDEEDVKLLGMsGk K134
NPM1 (rat) DEDEEDVKLLGMsGk K134
NPM1 iso2 (rat) DEDEEDVKLLGMSGK K134
S137-p
EEDVkLLsIsGkRsA
Upstream
1 25
Kinase, in vitro:
  • CDC7 (human)
Treatment
  • AZD1152
  • MLN8054
  • nocodazole
  • ZM447439
view more >
NPM1 (human) EEDVkLLsIsGkRsA S137-p
NPM1 iso2 (human) EEDVKLLsISGkRsA S137-p
NPM1 iso3 (human) EEDVKLLSISGKRSA S137
NPM1 (mouse) EEDVKLLGMsGkRsA G137
NPM1 (rat) EEDVKLLGMsGkRSA G137
NPM1 iso2 (rat) EEDVKLLGMSGKRSA G137
S139-p
DVkLLsIsGkRsAPG
Upstream
0 22
Treatment
  • BI2536
  • nocodazole
NPM1 (human) DVkLLsIsGkRsAPG S139-p
NPM1 iso2 (human) DVKLLsISGkRsAPG S139
NPM1 iso3 (human) DVKLLSISGKRSAPG S139
NPM1 (mouse) DVKLLGMsGkRsAPG S139-p
NPM1 (rat) DVKLLGMsGkRSAPG S139-p
NPM1 iso2 (rat) DVKLLGMSGKRSAPG S139
K141-ac
kLLsIsGkRsAPGGG
0 155
NPM1 (human) kLLsIsGkRsAPGGG K141-ac
NPM1 iso2 (human) KLLsISGkRsAPGGG K141-ac
NPM1 iso3 (human) KLLSISGKRSAPGGG K141
NPM1 (mouse) KLLGMsGkRsAPGGG K141-ac
NPM1 (rat) KLLGMsGkRSAPGGG K141-ac
NPM1 iso2 (rat) KLLGMSGKRSAPGGG K141
K141-ub
kLLsIsGkRsAPGGG
0 10
NPM1 (human) kLLsIsGkRsAPGGG K141-ub
NPM1 iso2 (human) KLLsISGKRsAPGGG K141
NPM1 iso3 (human) KLLSISGKRSAPGGG K141
NPM1 (mouse) KLLGMsGkRsAPGGG K141-ub
NPM1 (rat) KLLGMsGKRSAPGGG K141
NPM1 iso2 (rat) KLLGMSGKRSAPGGG K141
K141-sc
kLLsIsGkRsAPGGG
0 1
NPM1 (human) kLLsIsGkRsAPGGG K141-sc
NPM1 iso2 (human) KLLsISGKRsAPGGG K141
NPM1 iso3 (human) KLLSISGKRSAPGGG K141
NPM1 (mouse) KLLGMsGKRsAPGGG K141
NPM1 (rat) KLLGMsGKRSAPGGG K141
NPM1 iso2 (rat) KLLGMSGKRSAPGGG K141
K141-sm
kLLsIsGkRsAPGGG
0 2
NPM1 (human) kLLsIsGkRsAPGGG K141-sm
NPM1 iso2 (human) KLLsISGKRsAPGGG K141
NPM1 iso3 (human) KLLSISGKRSAPGGG K141
NPM1 (mouse) KLLGMsGKRsAPGGG K141
NPM1 (rat) KLLGMsGKRSAPGGG K141
NPM1 iso2 (rat) KLLGMSGKRSAPGGG K141
K141-m1
kLLsIsGkRsAPGGG
0 1
NPM1 (human) kLLsIsGkRsAPGGG K141-m1
NPM1 iso2 (human) KLLsISGKRsAPGGG K141
NPM1 iso3 (human) KLLSISGKRSAPGGG K141
NPM1 (mouse) KLLGMsGKRsAPGGG K141
NPM1 (rat) KLLGMsGKRSAPGGG K141
NPM1 iso2 (rat) KLLGMSGKRSAPGGG K141
S143-p
LsIsGkRsAPGGGsk
0 8
NPM1 (human) LsIsGkRsAPGGGsk S143-p
NPM1 iso2 (human) LsISGkRsAPGGGSk S143-p
NPM1 iso3 (human) LSISGKRSAPGGGSK S143
NPM1 (mouse) LGMsGkRsAPGGGNk S143-p
NPM1 (rat) LGMsGkRSAPGGGNk S143
NPM1 iso2 (rat) LGMSGKRSAPGGGNK S143
S149-p
RsAPGGGskVPQkkV
0 3
NPM1 (human) RsAPGGGskVPQkkV S149-p
NPM1 iso2 (human) RsAPGGGSkVPQkkV S149
NPM1 iso3 (human) RSAPGGGSKVPQKKV S149
NPM1 (mouse) RsAPGGGNkVPQkkV N149
NPM1 (rat) RSAPGGGNkVPQkKV N149
NPM1 iso2 (rat) RSAPGGGNKVPQKKV N149
K150-ac
sAPGGGskVPQkkVk
0 67
NPM1 (human) sAPGGGskVPQkkVk K150-ac
NPM1 iso2 (human) sAPGGGSkVPQkkVK K150-ac
NPM1 iso3 (human) SAPGGGSKVPQKKVK K150
NPM1 (mouse) sAPGGGNkVPQkkVK K150-ac
NPM1 (rat) SAPGGGNkVPQkKVK K150-ac
NPM1 iso2 (rat) SAPGGGNKVPQKKVK K150
K150-ub
sAPGGGskVPQkkVk
0 3
NPM1 (human) sAPGGGskVPQkkVk K150-ub
NPM1 iso2 (human) sAPGGGSKVPQkkVK K150
NPM1 iso3 (human) SAPGGGSKVPQKKVK K150
NPM1 (mouse) sAPGGGNKVPQkkVK K150
NPM1 (rat) SAPGGGNKVPQkKVK K150
NPM1 iso2 (rat) SAPGGGNKVPQKKVK K150
K150-sm
sAPGGGskVPQkkVk
0 2
NPM1 (human) sAPGGGskVPQkkVk K150-sm
NPM1 iso2 (human) sAPGGGSKVPQkkVK K150
NPM1 iso3 (human) SAPGGGSKVPQKKVK K150
NPM1 (mouse) sAPGGGNKVPQkkVK K150
NPM1 (rat) SAPGGGNKVPQkKVK K150
NPM1 iso2 (rat) SAPGGGNKVPQKKVK K150
K154-ac
GGskVPQkkVkLAAD
0 238
NPM1 (human) GGskVPQkkVkLAAD K154-ac
NPM1 iso2 (human) GGSkVPQkkVKLAAD K154-ac
NPM1 iso3 (human) GGSKVPQKKVKLAAD K154
NPM1 (mouse) GGNkVPQkkVKLDED K154-ac
NPM1 (rat) GGNkVPQkKVKLDED K154-ac
NPM1 iso2 (rat) GGNKVPQKKVKLDED K154
K154
GGskVPQKkVkLAAD
0 1
NPM1 (human) GGskVPQKkVkLAAD K154
NPM1 iso2 (human) GGSkVPQKkVKLAAD K154
NPM1 iso3 (human) GGSKVPQKKVKLAAD K154
NPM1 (mouse) GGNkVPQkkVKLDED K154-ub
NPM1 (rat) GGNkVPQKKVKLDED K154
NPM1 iso2 (rat) GGNKVPQKKVKLDED K154
K155-ac
GskVPQkkVkLAADE
0 16
NPM1 (human) GskVPQkkVkLAADE K155-ac
NPM1 iso2 (human) GSkVPQkkVKLAADE K155-ac
NPM1 iso3 (human) GSKVPQKKVKLAADE K155
NPM1 (mouse) GNkVPQkkVKLDEDD K155-ac
NPM1 (rat) GNkVPQkKVKLDEDD K155
NPM1 iso2 (rat) GNKVPQKKVKLDEDD K155
K155-ub
GskVPQkkVkLAADE
0 1
NPM1 (human) GskVPQkkVkLAADE K155-ub
NPM1 iso2 (human) GSkVPQkKVKLAADE K155
NPM1 iso3 (human) GSKVPQKKVKLAADE K155
NPM1 (mouse) GNkVPQkKVKLDEDD K155
NPM1 (rat) GNkVPQkKVKLDEDD K155
NPM1 iso2 (rat) GNKVPQKKVKLDEDD K155
K157-ub
kVPQkkVkLAADEDD
0 1
NPM1 (human) kVPQkkVkLAADEDD K157-ub
NPM1 iso2 (human) kVPQkkVKLAADEDD K157
NPM1 iso3 (human) KVPQKKVKLAADEDD K157
NPM1 (mouse) kVPQkkVKLDEDDED K157
NPM1 (rat) kVPQkKVKLDEDDDE K157
NPM1 iso2 (rat) KVPQKKVKLDEDDDE K157
K157-ac
kVPQkkVkLAADEDD
0 4
NPM1 (human) kVPQkkVkLAADEDD K157-ac
NPM1 iso2 (human) kVPQkkVKLAADEDD K157
NPM1 iso3 (human) KVPQKKVKLAADEDD K157
NPM1 (mouse) kVPQkkVKLDEDDED K157
NPM1 (rat) kVPQkKVKLDEDDDE K157
NPM1 iso2 (rat) KVPQKKVKLDEDDDE K157
A186
DDFDDEEAEEkAPVk
0 3
NPM1 (human) DDFDDEEAEEkAPVk A186
NPM1 iso2 (human) DDFDDEEAEEKAPVK A186
NPM1 iso3 (human) DDFDDEEAEEKAPVK A186
NPM1 (mouse) DDFDEEEtEEKVPVK T185-p
NPM1 (rat) DDFDEEETEEKVPVK T185
NPM1 iso2 (rat) DDFDEEETEEKVPVK T185
K189-ub
DDEEAEEkAPVkKsI
0 1
NPM1 (human) DDEEAEEkAPVkKsI K189-ub
NPM1 iso2 (human) DDEEAEEKAPVKKGQ K189
NPM1 iso3 (human) DDEEAEEKAPVKKSI K189
NPM1 (mouse) DEEEtEEKVPVKKsV K188
NPM1 (rat) DEEETEEKVPVKKSV K188
NPM1 iso2 (rat) DEEETEEKVPVKKSV K188
K193-ub
AEEkAPVkKsIrDtP
0 1
NPM1 (human) AEEkAPVkKsIrDtP K193-ub
NPM1 iso2 (human) AEEKAPVKKGQEsFk K193
NPM1 iso3 (human) AEEKAPVKKSIRDTP K193
NPM1 (mouse) tEEKVPVKKsVRdtP K192
NPM1 (rat) TEEKVPVKKSVRDTP K192
NPM1 iso2 (rat) TEEKVPVKKSVRDTP K192
S195-p
EkAPVkKsIrDtPAk
0 13
NPM1 (human) EkAPVkKsIrDtPAk S195-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) EKAPVKKSIRDTPAK S195
NPM1 (mouse) EKVPVKKsVRdtPAK S194-p
NPM1 (rat) EKVPVKKSVRDTPAK S194
NPM1 iso2 (rat) EKVPVKKSVRDTPAK S194
R197-m1
APVkKsIrDtPAkNA
0 1
NPM1 (human) APVkKsIrDtPAkNA R197-m1
NPM1 iso2 (human) gap -
NPM1 iso3 (human) APVKKSIRDTPAKNA R197
NPM1 (mouse) VPVKKsVRdtPAKNA R196
NPM1 (rat) VPVKKSVRDTPAKNA R196
NPM1 iso2 (rat) VPVKKSVRDTPAKNA R196
D198
PVkKsIrDtPAkNAQ
0 1
NPM1 (human) PVkKsIrDtPAkNAQ D198
NPM1 iso2 (human) gap -
NPM1 iso3 (human) PVKKSIRDTPAKNAQ D198
NPM1 (mouse) PVKKsVRdtPAKNAQ D197-ca
NPM1 (rat) PVKKSVRDTPAKNAQ D197
NPM1 iso2 (rat) PVKKSVRDTPAKNAQ D197
T199-p
VkKsIrDtPAkNAQK
Upstream
Downstream
24 54
NPM1 (human)
T199-p
NPM1 (mouse)
T198-p
NPM1 (rat)
T198-p
Effects on Modified Protein
  • acetylation
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • transcription, inhibited
Kinase, in vitro:
  • CDC7 (human)
  • CDK1 (human)
  • CDK2 (human)
  • Cot (human)
view more >
Putative in vivo kinases:
  • CDK1 (human)
  • CDK6 (human)
  • Cot (human)
view more >
Regulatory protein:
  • BRCA1 (human)
  • CDK6 (human)
  • CTNND1 (human)
  • FBXW7 (human)
  • RAP80 (human)
  • RNF8 (human)
  • UBE2N (human)
view more >
Treatment
  • EGF
  • ionizing_radiation
  • ischemia
  • KBrO3
  • metastatic potential
  • MG132
  • MG132_withdrawal
  • N6L
  • neocarzinostatin
  • nocodazole
  • PHA533533
  • prexasertib
  • RITA
  • RO-3306
  • triptolide
  • U0126
  • UVC
  • virus infection
view more >
NPM1 (human) VkKsIrDtPAkNAQK T199-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) VKKSIRDTPAKNAQK T199
NPM1 (mouse) VKKsVRdtPAKNAQK T198-p
NPM1 (rat) VKKSVRDTPAKNAQK T198
NPM1 iso2 (rat) VKKSVRDTPAKNAQK T198
K202-ub
sIrDtPAkNAQKsNQ
0 5
NPM1 (human) sIrDtPAkNAQKsNQ K202-ub
NPM1 iso2 (human) gap -
NPM1 iso3 (human) SIRDTPAKNAQKSNQ K202
NPM1 (mouse) sVRdtPAKNAQKSNQ K201
NPM1 (rat) SVRDTPAKNAQKSNQ K201
NPM1 iso2 (rat) SVRDTPAKNAQKSNQ K201
K202-sm
sIrDtPAkNAQKsNQ
0 1
NPM1 (human) sIrDtPAkNAQKsNQ K202-sm
NPM1 iso2 (human) gap -
NPM1 iso3 (human) SIRDTPAKNAQKSNQ K202
NPM1 (mouse) sVRdtPAKNAQKSNQ K201
NPM1 (rat) SVRDTPAKNAQKSNQ K201
NPM1 iso2 (rat) SVRDTPAKNAQKSNQ K201
S207-p
PAkNAQKsNQNGkDs
0 3
NPM1 (human) PAkNAQKsNQNGkDs S207-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) PAKNAQKSNQNGKDS S207
NPM1 (mouse) PAKNAQKSNQNGkDL S206
NPM1 (rat) PAKNAQKSNQNGkDL S206
NPM1 iso2 (rat) PAKNAQKSNQNGKDL S206
K212-ac
QKsNQNGkDskPsst
Downstream
1 36
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) QKsNQNGkDskPsst K212-ac
NPM1 iso2 (human) gap -
NPM1 iso3 (human) QKSNQNGKDSKPSST K212
NPM1 (mouse) QKSNQNGkDLKPstP K211-ac
NPM1 (rat) QKSNQNGkDLkPSTP K211-ac
NPM1 iso2 (rat) QKSNQNGKDLKPSTP K211
K212-sc
QKsNQNGkDskPsst
0 1
NPM1 (human) QKsNQNGkDskPsst K212-sc
NPM1 iso2 (human) gap -
NPM1 iso3 (human) QKSNQNGKDSKPSST K212
NPM1 (mouse) QKSNQNGKDLKPstP K211
NPM1 (rat) QKSNQNGKDLkPSTP K211
NPM1 iso2 (rat) QKSNQNGKDLKPSTP K211
S214-p
sNQNGkDskPsstPR
0 7
NPM1 (human) sNQNGkDskPsstPR S214-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) SNQNGKDSKPSSTPR S214
NPM1 (mouse) SNQNGkDLKPstPRs L213
NPM1 (rat) SNQNGkDLkPSTPRS L213
NPM1 iso2 (rat) SNQNGKDLKPSTPRS L213
K215-ac
NQNGkDskPsstPRs
Downstream
1 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) NQNGkDskPsstPRs K215-ac
NPM1 iso2 (human) gap -
NPM1 iso3 (human) NQNGKDSKPSSTPRS K215
NPM1 (mouse) NQNGkDLKPstPRsk K214
NPM1 (rat) NQNGkDLkPSTPRSk K214-ac
NPM1 iso2 (rat) NQNGKDLKPSTPRSK K214
K215-sm
NQNGkDskPsstPRs
0 1
NPM1 (human) NQNGkDskPsstPRs K215-sm
NPM1 iso2 (human) gap -
NPM1 iso3 (human) NQNGKDSKPSSTPRS K215
NPM1 (mouse) NQNGkDLKPstPRsk K214
NPM1 (rat) NQNGkDLKPSTPRSk K214
NPM1 iso2 (rat) NQNGKDLKPSTPRSK K214
S217-p
NGkDskPsstPRskG
0 12
NPM1 (human) NGkDskPsstPRskG S217-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) NGKDSKPSSTPRSKG S217
NPM1 (mouse) NGkDLKPstPRskGQ S216-p
NPM1 (rat) NGkDLkPSTPRSkGQ S216
NPM1 iso2 (rat) NGKDLKPSTPRSKGQ S216
S218-p
GkDskPsstPRskGQ
0 14
NPM1 (human) GkDskPsstPRskGQ S218-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) GKDSKPSSTPRSKGQ S218
NPM1 (mouse) gap -
NPM1 (rat) gap -
NPM1 iso2 (rat) gap -
T219-p
kDskPsstPRskGQE
Upstream
Downstream
1 43
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CDK1 (human)
Treatment
  • MG132_withdrawal
  • nocodazole
NPM1 (human) kDskPsstPRskGQE T219-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) KDSKPSSTPRSKGQE T219
NPM1 (mouse) GkDLKPstPRskGQE T217-p
NPM1 (rat) GkDLkPSTPRSkGQE T217
NPM1 iso2 (rat) GKDLKPSTPRSKGQE T217
S222-p
kPsstPRskGQEsFk
0 8
NPM1 (human) kPsstPRskGQEsFk S222-p
NPM1 iso2 (human) gap -
NPM1 iso3 (human) KPSSTPRSKGQESFK S222
NPM1 (mouse) LKPstPRskGQEsFk S220-p
NPM1 (rat) LkPSTPRSkGQESFk S220
NPM1 iso2 (rat) LKPSTPRSKGQESFK S220
K223-ac
PsstPRskGQEsFkk
0 8
NPM1 (human) PsstPRskGQEsFkk K223-ac
NPM1 iso2 (human) EEKAPVKKGQEsFkK K194
NPM1 iso3 (human) PSSTPRSKGQESFKK K223
NPM1 (mouse) KPstPRskGQEsFkk K221-ac
NPM1 (rat) kPSTPRSkGQESFkK K221-ac
NPM1 iso2 (rat) KPSTPRSKGQESFKK K221
K223-ub
PsstPRskGQEsFkk
0 2
NPM1 (human) PsstPRskGQEsFkk K223-ub
NPM1 iso2 (human) EEKAPVKKGQEsFkK K194
NPM1 iso3 (human) PSSTPRSKGQESFKK K223
NPM1 (mouse) KPstPRsKGQEsFkk K221
NPM1 (rat) kPSTPRSKGQESFkK K221
NPM1 iso2 (rat) KPSTPRSKGQESFKK K221
K223-m1
PsstPRskGQEsFkk
0 14
NPM1 (human) PsstPRskGQEsFkk K223-m1
NPM1 iso2 (human) EEKAPVKKGQEsFkK K194
NPM1 iso3 (human) PSSTPRSKGQESFKK K223
NPM1 (mouse) KPstPRsKGQEsFkk K221
NPM1 (rat) kPSTPRSKGQESFkK K221
NPM1 iso2 (rat) KPSTPRSKGQESFKK K221
K223-sm
PsstPRskGQEsFkk
0 1
NPM1 (human) PsstPRskGQEsFkk K223-sm
NPM1 iso2 (human) EEKAPVKKGQEsFkK K194
NPM1 iso3 (human) PSSTPRSKGQESFKK K223
NPM1 (mouse) KPstPRsKGQEsFkk K221
NPM1 (rat) kPSTPRSKGQESFkK K221
NPM1 iso2 (rat) KPSTPRSKGQESFKK K221
S227-p
PRskGQEsFkkQEKt
Upstream
0 19
Treatment
  • nocodazole
  • ZK-Thiazolidinone
NPM1 (human) PRskGQEsFkkQEKt S227-p
NPM1 iso2 (human) PVKKGQEsFkKQEKT S198-p
NPM1 iso3 (human) PRSKGQESFKKQEKT S227
NPM1 (mouse) PRskGQEsFkkQEKt S225-p
NPM1 (rat) PRSkGQESFkKQEKT S225
NPM1 iso2 (rat) PRSKGQESFKKQEKT S225
K229-ac
skGQEsFkkQEKtPK
Downstream
1 118
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) skGQEsFkkQEKtPK K229-ac
NPM1 iso2 (human) KKGQEsFkKQEKTPK K200-ac
NPM1 iso3 (human) SKGQESFKKQEKTPK K229
NPM1 (mouse) skGQEsFkkQEKtPK K227-ac
NPM1 (rat) SkGQESFkKQEKTPK K227-ac
NPM1 iso2 (rat) SKGQESFKKQEKTPK K227
K229-ub
skGQEsFkkQEKtPK
0 1
NPM1 (human) skGQEsFkkQEKtPK K229-ub
NPM1 iso2 (human) KKGQEsFKKQEKTPK K200
NPM1 iso3 (human) SKGQESFKKQEKTPK K229
NPM1 (mouse) skGQEsFKkQEKtPK K227
NPM1 (rat) SkGQESFKKQEKTPK K227
NPM1 iso2 (rat) SKGQESFKKQEKTPK K227
K229-sc
skGQEsFkkQEKtPK
0 1
NPM1 (human) skGQEsFkkQEKtPK K229-sc
NPM1 iso2 (human) KKGQEsFKKQEKTPK K200
NPM1 iso3 (human) SKGQESFKKQEKTPK K229
NPM1 (mouse) skGQEsFKkQEKtPK K227
NPM1 (rat) SkGQESFKKQEKTPK K227
NPM1 iso2 (rat) SKGQESFKKQEKTPK K227
K229-sm
skGQEsFkkQEKtPK
0 1
NPM1 (human) skGQEsFkkQEKtPK K229-sm
NPM1 iso2 (human) KKGQEsFKKQEKTPK K200
NPM1 iso3 (human) SKGQESFKKQEKTPK K229
NPM1 (mouse) skGQEsFKkQEKtPK K227
NPM1 (rat) SkGQESFKKQEKTPK K227
NPM1 iso2 (rat) SKGQESFKKQEKTPK K227
K230-sm
kGQEsFkkQEKtPKt
Downstream
3 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, induced
NPM1 (human) kGQEsFkkQEKtPKt K230-sm
NPM1 iso2 (human) KGQEsFkKQEKTPKt K201
NPM1 iso3 (human) KGQESFKKQEKTPKT K230
NPM1 (mouse) kGQEsFkKQEKtPKt K228
NPM1 (rat) kGQESFkKQEKTPKt K228
NPM1 iso2 (rat) KGQESFKKQEKTPKT K228
K230-ac
kGQEsFkkQEKtPKt
Downstream
1 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) kGQEsFkkQEKtPKt K230-ac
NPM1 iso2 (human) KGQEsFkKQEKTPKt K201
NPM1 iso3 (human) KGQESFKKQEKTPKT K230
NPM1 (mouse) kGQEsFkkQEKtPKt K228-ac
NPM1 (rat) kGQESFkKQEKTPKt K228
NPM1 iso2 (rat) KGQESFKKQEKTPKT K228
T234-p
sFkkQEKtPKtPkGP
Upstream
Downstream
7 35
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, induced
  • cell motility, induced
  • cytoskeletal reorganization
Kinase, in vitro:
  • CDK1 (human)
  • CDK2 (human)
Putative in vivo kinases:
  • CDK1 (human)
Treatment
  • ionizing_radiation
  • N6L
  • nocodazole
  • seliciclib
  • staurosporine
view more >
NPM1 (human) sFkkQEKtPKtPkGP T234-p
NPM1 iso2 (human) sFkKQEKTPKtPKGP T205
NPM1 iso3 (human) SFKKQEKTPKTPKGP T234
NPM1 (mouse) sFkkQEKtPKtPkGP T232-p
NPM1 (rat) SFkKQEKTPKtPkGP T232
NPM1 iso2 (rat) SFKKQEKTPKTPKGP T232
T237-p
kQEKtPKtPkGPssV
Upstream
Downstream
6 44
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, induced
  • cell motility, induced
  • cytoskeletal reorganization
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Regulatory protein:
  • OGT (human)
Treatment
  • ionizing_radiation
  • N6L
  • nocodazole
  • seliciclib
  • staurosporine
view more >
NPM1 (human) kQEKtPKtPkGPssV T237-p
NPM1 iso2 (human) KQEKTPKtPKGPSSV T208-p
NPM1 iso3 (human) KQEKTPKTPKGPSSV T237
NPM1 (mouse) kQEKtPKtPkGPssV T235-p
NPM1 (rat) KQEKTPKtPkGPSsV T235-p
NPM1 iso2 (rat) KQEKTPKTPKGPSSV T235
K239-ub
EKtPKtPkGPssVED
0 7
NPM1 (human) EKtPKtPkGPssVED K239-ub
NPM1 iso2 (human) EKTPKtPKGPSSVED K210
NPM1 iso3 (human) EKTPKTPKGPSSVED K239
NPM1 (mouse) EKtPKtPkGPssVED K237-ub
NPM1 (rat) EKTPKtPKGPSsVED K237
NPM1 iso2 (rat) EKTPKTPKGPSSVED K237
K239-sc
EKtPKtPkGPssVED
0 1
NPM1 (human) EKtPKtPkGPssVED K239-sc
NPM1 iso2 (human) EKTPKtPKGPSSVED K210
NPM1 iso3 (human) EKTPKTPKGPSSVED K239
NPM1 (mouse) EKtPKtPKGPssVED K237
NPM1 (rat) EKTPKtPKGPSsVED K237
NPM1 iso2 (rat) EKTPKTPKGPSSVED K237
K239
EKtPKtPKGPssVED
0 1
NPM1 (human) EKtPKtPKGPssVED K239
NPM1 iso2 (human) EKTPKtPKGPSSVED K210
NPM1 iso3 (human) EKTPKTPKGPSSVED K239
NPM1 (mouse) EKtPKtPKGPssVED K237
NPM1 (rat) EKTPKtPkGPSsVED K237-ac
NPM1 iso2 (rat) EKTPKTPKGPSSVED K237
K239-sm
EKtPKtPkGPssVED
0 2
NPM1 (human) EKtPKtPkGPssVED K239-sm
NPM1 iso2 (human) EKTPKtPKGPSSVED K210
NPM1 iso3 (human) EKTPKTPKGPSSVED K239
NPM1 (mouse) EKtPKtPKGPssVED K237
NPM1 (rat) EKTPKtPKGPSsVED K237
NPM1 iso2 (rat) EKTPKTPKGPSSVED K237
S242-p
PKtPkGPssVEDIkA
Upstream
0 16
Regulatory protein:
  • OGT (human)
Treatment
  • nocodazole
NPM1 (human) PKtPkGPssVEDIkA S242-p
NPM1 iso2 (human) PKtPKGPSSVEDIKA S213
NPM1 iso3 (human) PKTPKGPSSVEDIKA S242
NPM1 (mouse) PKtPkGPssVEDIkA S240-p
NPM1 (rat) PKtPkGPSsVEDIkA S240
NPM1 iso2 (rat) PKTPKGPSSVEDIKA S240
S243-p
KtPkGPssVEDIkAk
Upstream
0 53
Regulatory protein:
  • OGT (human)
Treatment
  • EGF
  • nocodazole
  • SB202190
view more >
NPM1 (human) KtPkGPssVEDIkAk S243-p
NPM1 iso2 (human) KtPKGPSSVEDIKAK S214
NPM1 iso3 (human) KTPKGPSSVEDIKAK S243
NPM1 (mouse) KtPkGPssVEDIkAk S241-p
NPM1 (rat) KtPkGPSsVEDIkAk S241-p
NPM1 iso2 (rat) KTPKGPSSVEDIKAK S241
K248-ub
PssVEDIkAkMQAsI
0 20
NPM1 (human) PssVEDIkAkMQAsI K248-ub
NPM1 iso2 (human) PSSVEDIKAKMQASI K219
NPM1 iso3 (human) PSSVEDIKAKMQAsI K248
NPM1 (mouse) PssVEDIkAkMQAsI K246-ub
NPM1 (rat) PSsVEDIKAkMQAsI K246
NPM1 iso2 (rat) PSSVEDIKAKMQASI K246
K248-sc
PssVEDIkAkMQAsI
0 1
NPM1 (human) PssVEDIkAkMQAsI K248-sc
NPM1 iso2 (human) PSSVEDIKAKMQASI K219
NPM1 iso3 (human) PSSVEDIKAKMQAsI K248
NPM1 (mouse) PssVEDIKAkMQAsI K246
NPM1 (rat) PSsVEDIKAkMQAsI K246
NPM1 iso2 (rat) PSSVEDIKAKMQASI K246
K248-ac
PssVEDIkAkMQAsI
0 3
NPM1 (human) PssVEDIkAkMQAsI K248-ac
NPM1 iso2 (human) PSSVEDIKAKMQASI K219
NPM1 iso3 (human) PSSVEDIKAKMQAsI K248
NPM1 (mouse) PssVEDIKAkMQAsI K246
NPM1 (rat) PSsVEDIkAkMQAsI K246-ac
NPM1 iso2 (rat) PSSVEDIKAKMQASI K246
K248-sm
PssVEDIkAkMQAsI
0 3
NPM1 (human) PssVEDIkAkMQAsI K248-sm
NPM1 iso2 (human) PSSVEDIKAKMQASI K219
NPM1 iso3 (human) PSSVEDIKAKMQAsI K248
NPM1 (mouse) PssVEDIKAkMQAsI K246
NPM1 (rat) PSsVEDIKAkMQAsI K246
NPM1 iso2 (rat) PSSVEDIKAKMQASI K246
K248-m1
PssVEDIkAkMQAsI
0 1
NPM1 (human) PssVEDIkAkMQAsI K248-m1
NPM1 iso2 (human) PSSVEDIKAKMQASI K219
NPM1 iso3 (human) PSSVEDIKAKMQAsI K248
NPM1 (mouse) PssVEDIKAkMQAsI K246
NPM1 (rat) PSsVEDIKAkMQAsI K246
NPM1 iso2 (rat) PSSVEDIKAKMQASI K246
K250-ub
sVEDIkAkMQAsIEk
0 15
NPM1 (human) sVEDIkAkMQAsIEk K250-ub
NPM1 iso2 (human) SVEDIKAKMQASIEK K221
NPM1 iso3 (human) SVEDIKAKMQAsIEk K250
NPM1 (mouse) sVEDIkAkMQAsIEk K248-ub
NPM1 (rat) sVEDIkAKMQAsIEk K248
NPM1 iso2 (rat) SVEDIKAKMQASIEk K248
K250-ac
sVEDIkAkMQAsIEk
0 14
NPM1 (human) sVEDIkAkMQAsIEk K250-ac
NPM1 iso2 (human) SVEDIKAKMQASIEK K221
NPM1 iso3 (human) SVEDIKAKMQAsIEk K250
NPM1 (mouse) sVEDIkAKMQAsIEk K248
NPM1 (rat) sVEDIkAkMQAsIEk K248-ac
NPM1 iso2 (rat) SVEDIKAKMQASIEk K248
K250-sm
sVEDIkAkMQAsIEk
0 1
NPM1 (human) sVEDIkAkMQAsIEk K250-sm
NPM1 iso2 (human) SVEDIKAKMQASIEK K221
NPM1 iso3 (human) SVEDIKAKMQAsIEk K250
NPM1 (mouse) sVEDIkAKMQAsIEk K248
NPM1 (rat) sVEDIkAKMQAsIEk K248
NPM1 iso2 (rat) SVEDIKAKMQASIEk K248
S254-p
IkAkMQAsIEkGGsL
Upstream
0 54
Regulatory protein:
  • OGT (human)
Treatment
  • ionizing_radiation
  • metformin
  • MG132_withdrawal
  • nocodazole
  • SII_angiotensin_2
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NPM1 (human) IkAkMQAsIEkGGsL S254-p
NPM1 iso2 (human) IKAKMQASIEKGGSL S225
NPM1 iso3 (human) IKAKMQAsIEkAH__ S254-p
NPM1 (mouse) IkAkMQAsIEkGGsL S252-p
NPM1 (rat) IkAkMQAsIEkGGsL S252-p
NPM1 iso2 (rat) IKAKMQASIEkAH__ S252
K257-ac
kMQAsIEkGGsLPkV
Downstream
1 7
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) kMQAsIEkGGsLPkV K257-ac
NPM1 iso2 (human) KMQASIEKGGSLPKV K228
NPM1 iso3 (human) KMQAsIEkAH_____ K257-ac
NPM1 (mouse) kMQAsIEkGGsLPkV K255-ac
NPM1 (rat) kMQAsIEkGGsLPKV K255-ac
NPM1 iso2 (rat) KMQASIEkAH_____ K255-ac
K257-ub
kMQAsIEkGGsLPkV
0 15
NPM1 (human) kMQAsIEkGGsLPkV K257-ub
NPM1 iso2 (human) KMQASIEKGGSLPKV K228
NPM1 iso3 (human) KMQAsIEKAH_____ K257
NPM1 (mouse) kMQAsIEkGGsLPkV K255-ub
NPM1 (rat) kMQAsIEKGGsLPKV K255
NPM1 iso2 (rat) KMQASIEKAH_____ K255
K257-sm
kMQAsIEkGGsLPkV
0 2
NPM1 (human) kMQAsIEkGGsLPkV K257-sm
NPM1 iso2 (human) KMQASIEKGGSLPKV K228
NPM1 iso3 (human) KMQAsIEKAH_____ K257
NPM1 (mouse) kMQAsIEKGGsLPkV K255
NPM1 (rat) kMQAsIEKGGsLPKV K255
NPM1 iso2 (rat) KMQASIEKAH_____ K255
S260-p
AsIEkGGsLPkVEAk
Upstream
0 33
Treatment
  • BI_4834
  • metformin
  • nocodazole
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NPM1 (human) AsIEkGGsLPkVEAk S260-p
NPM1 iso2 (human) ASIEKGGSLPKVEAk S231
NPM1 iso3 (human) gap -
NPM1 (mouse) AsIEkGGsLPkVEAk S258-p
NPM1 (rat) AsIEkGGsLPKVEAk S258-p
NPM1 iso2 (rat) gap -
K263-sm
EkGGsLPkVEAkFIN
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, induced
NPM1 (human) EkGGsLPkVEAkFIN K263-sm
NPM1 iso2 (human) EKGGSLPKVEAkFIN K234
NPM1 iso3 (human) gap -
NPM1 (mouse) EkGGsLPKVEAkFIN K261
NPM1 (rat) EkGGsLPKVEAkFIN K261
NPM1 iso2 (rat) gap -
K263-ub
EkGGsLPkVEAkFIN
0 6
NPM1 (human) EkGGsLPkVEAkFIN K263-ub
NPM1 iso2 (human) EKGGSLPKVEAkFIN K234
NPM1 iso3 (human) gap -
NPM1 (mouse) EkGGsLPkVEAkFIN K261-ub
NPM1 (rat) EkGGsLPKVEAkFIN K261
NPM1 iso2 (rat) gap -
K267-ac
sLPkVEAkFINyVkN
Upstream
Downstream
1 142
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
Treatment
  • vorinostat
NPM1 (human) sLPkVEAkFINyVkN K267-ac
NPM1 iso2 (human) SLPKVEAkFINYVKN K238-ac
NPM1 iso3 (human) gap -
NPM1 (mouse) sLPkVEAkFINYVkN K265-ac
NPM1 (rat) sLPKVEAkFINYVKN K265-ac
NPM1 iso2 (rat) gap -
K267-ub
sLPkVEAkFINyVkN
0 43
NPM1 (human) sLPkVEAkFINyVkN K267-ub
NPM1 iso2 (human) SLPKVEAKFINYVKN K238
NPM1 iso3 (human) gap -
NPM1 (mouse) sLPkVEAkFINYVkN K265-ub
NPM1 (rat) sLPKVEAKFINYVKN K265
NPM1 iso2 (rat) gap -
K267-sc
sLPkVEAkFINyVkN
0 1
NPM1 (human) sLPkVEAkFINyVkN K267-sc
NPM1 iso2 (human) SLPKVEAKFINYVKN K238
NPM1 iso3 (human) gap -
NPM1 (mouse) sLPkVEAKFINYVkN K265
NPM1 (rat) sLPKVEAKFINYVKN K265
NPM1 iso2 (rat) gap -
K267-sm
sLPkVEAkFINyVkN
0 3
NPM1 (human) sLPkVEAkFINyVkN K267-sm
NPM1 iso2 (human) SLPKVEAKFINYVKN K238
NPM1 iso3 (human) gap -
NPM1 (mouse) sLPkVEAKFINYVkN K265
NPM1 (rat) sLPKVEAKFINYVKN K265
NPM1 iso2 (rat) gap -
Y271-p
VEAkFINyVkNCFRM
0 1
NPM1 (human) VEAkFINyVkNCFRM Y271-p
NPM1 iso2 (human) VEAkFINYVKNCFRM Y242
NPM1 iso3 (human) gap -
NPM1 (mouse) VEAkFINYVkNCFRM Y269
NPM1 (rat) VEAkFINYVKNCFRM Y269
NPM1 iso2 (rat) gap -
K273-ac
AkFINyVkNCFRMtD
Upstream
0 17
Treatment
  • MS275
NPM1 (human) AkFINyVkNCFRMtD K273-ac
NPM1 iso2 (human) AkFINYVKNCFRMtD K244
NPM1 iso3 (human) gap -
NPM1 (mouse) AkFINYVkNCFRMTD K271-ac
NPM1 (rat) AkFINYVKNCFRMTD K271
NPM1 iso2 (rat) gap -
K273-ub
AkFINyVkNCFRMtD
0 20
NPM1 (human) AkFINyVkNCFRMtD K273-ub
NPM1 iso2 (human) AkFINYVKNCFRMtD K244
NPM1 iso3 (human) gap -
NPM1 (mouse) AkFINYVkNCFRMTD K271-ub
NPM1 (rat) AkFINYVKNCFRMTD K271
NPM1 iso2 (rat) gap -
K273-sc
AkFINyVkNCFRMtD
0 1
NPM1 (human) AkFINyVkNCFRMtD K273-sc
NPM1 iso2 (human) AkFINYVKNCFRMtD K244
NPM1 iso3 (human) gap -
NPM1 (mouse) AkFINYVKNCFRMTD K271
NPM1 (rat) AkFINYVKNCFRMTD K271
NPM1 iso2 (rat) gap -
K273-m1
AkFINyVkNCFRMtD
0 1
NPM1 (human) AkFINyVkNCFRMtD K273-m1
NPM1 iso2 (human) AkFINYVKNCFRMtD K244
NPM1 iso3 (human) gap -
NPM1 (mouse) AkFINYVKNCFRMTD K271
NPM1 (rat) AkFINYVKNCFRMTD K271
NPM1 iso2 (rat) gap -
T279-p
VkNCFRMtDQEAIQD
Upstream
0 17
Treatment
  • nocodazole
NPM1 (human) VkNCFRMtDQEAIQD T279-p
NPM1 iso2 (human) VKNCFRMtDQEAIQD T250-p
NPM1 iso3 (human) gap -
NPM1 (mouse) VkNCFRMTDQEAIQD T277
NPM1 (rat) VKNCFRMTDQEAIQD T277
NPM1 iso2 (rat) gap -
K292-ac
QDLWQWRksL_____
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
NPM1 (human) QDLWQWRksL_____ K292-ac
NPM1 iso2 (human) QDLWQWRKSL_____ K263
NPM1 iso3 (human) gap -
NPM1 (mouse) QDLWQWRKSL_____ K290
NPM1 (rat) QDLWQWRKSL_____ K290
NPM1 iso2 (rat) gap -
K292-sm
QDLWQWRksL_____
0 1
NPM1 (human) QDLWQWRksL_____ K292-sm
NPM1 iso2 (human) QDLWQWRKSL_____ K263
NPM1 iso3 (human) gap -
NPM1 (mouse) QDLWQWRKSL_____ K290
NPM1 (rat) QDLWQWRKSL_____ K290
NPM1 iso2 (rat) gap -
S293-p
DLWQWRksL______
0 9
NPM1 (human) DLWQWRksL______ S293-p
NPM1 iso2 (human) DLWQWRKSL______ S264
NPM1 iso3 (human) gap -
NPM1 (mouse) DLWQWRKSL______ S291
NPM1 (rat) DLWQWRKSL______ S291
NPM1 iso2 (rat) gap -