Other Species / Isoforms
  HSP90A (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 1
HSP90A (human) gap -
HSP90A iso2 (human) FLWHLMVsGsTTLLC S73-p
HSP90A (mouse) gap -
HSP90A (rat) gap -
HSP90A (hamster) gap -
-
gap
0 1
HSP90A (human) gap -
HSP90A iso2 (human) WHLMVsGsTTLLCLW S75-p
HSP90A (mouse) gap -
HSP90A (rat) gap -
HSP90A (hamster) gap -
T5-p
___MPEEtQtQDQPM
Upstream
2 0
HSP90A (human)
T5-p
HSP90A iso2 (human)
T127-p
HSP90A (mouse)
T5-p
HSP90A (rat)
T5-p
HSP90A (hamster)
T5-p
Kinase, in vitro:
  • DNAPK (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
HSP90A (human) ___MPEEtQtQDQPM T5-p
HSP90A iso2 (human) RLLMPEETQTQDQPM T127
HSP90A (mouse) ___MPEETQTQDQPM T5
HSP90A (rat) ___MPEETQTQDQPM T5
HSP90A (hamster) ___MPEETQTQDQPM T5
T7-p
_MPEEtQtQDQPMEE
Upstream
2 0
HSP90A (human)
T7-p
HSP90A iso2 (human)
T129-p
HSP90A (mouse)
T7-p
HSP90A (rat)
T7-p
HSP90A (hamster)
T7-p
Kinase, in vitro:
  • DNAPK (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
HSP90A (human) _MPEEtQtQDQPMEE T7-p
HSP90A iso2 (human) LMPEETQTQDQPMEE T129
HSP90A (mouse) _MPEETQTQDQPMEE T7
HSP90A (rat) _MPEETQTQDQPMEE T7
HSP90A (hamster) _MPEETQTQDQPMEE T7
T36-p
LMSLIINtFySNkEI
Upstream
Downstream
1 0
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, inhibited
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
HSP90A (human) LMSLIINtFySNkEI T36-p
HSP90A iso2 (human) LMSLIINTFYSNKEI T158
HSP90A (mouse) LMSLIINTFySNKEI T36
HSP90A (rat) LMSLIINTFYSNkEI T36
HSP90A (hamster) LMSLIINTFYSNKEI T36
Y38-p
SLIINtFySNkEIFL
Upstream
Downstream
1 27
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • Wee1 (human)
HSP90A (human) SLIINtFySNkEIFL Y38-p
HSP90A iso2 (human) SLIINTFYSNKEIFL Y160
HSP90A (mouse) SLIINTFySNKEIFL Y38-p
HSP90A (rat) SLIINTFYSNkEIFL Y38
HSP90A (hamster) SLIINTFYSNKEIFL Y38
K41-ub
INtFySNkEIFLREL
0 6
HSP90A (human) INtFySNkEIFLREL K41-ub
HSP90A iso2 (human) INTFYSNKEIFLREL K163
HSP90A (mouse) INTFySNKEIFLREL K41
HSP90A (rat) INTFYSNKEIFLREL K41
HSP90A (hamster) INTFYSNKEIFLREL K41
K41-ac
INtFySNkEIFLREL
0 2
HSP90A (human) INtFySNkEIFLREL K41-ac
HSP90A iso2 (human) INTFYSNKEIFLREL K163
HSP90A (mouse) INTFySNKEIFLREL K41
HSP90A (rat) INTFYSNkEIFLREL K41-ac
HSP90A (hamster) INTFYSNKEIFLREL K41
S52-p
LRELISNssDALDkI
0 4
HSP90A (human) LRELISNssDALDkI S52-p
HSP90A iso2 (human) LRELISNSSDALDKI S174
HSP90A (mouse) LRELISNsSDALDkI S52-p
HSP90A (rat) LRELISNSSDALDkI S52
HSP90A (hamster) LRELISNSSDALDKI S52
S53-p
RELISNssDALDkIR
0 1
HSP90A (human) RELISNssDALDkIR S53-p
HSP90A iso2 (human) RELISNSSDALDKIR S175
HSP90A (mouse) RELISNsSDALDkIR S53
HSP90A (rat) RELISNSSDALDkIR S53
HSP90A (hamster) RELISNSSDALDKIR S53
K58-ub
NssDALDkIRyEsLt
0 12
HSP90A (human) NssDALDkIRyEsLt K58-ub
HSP90A iso2 (human) NSSDALDKIRyESLT K180
HSP90A (mouse) NsSDALDkIRyEsLT K58-ub
HSP90A (rat) NSSDALDKIRYESLT K58
HSP90A (hamster) NSSDALDKIRYESLT K58
K58-ac
NssDALDkIRyEsLt
0 2
HSP90A (human) NssDALDkIRyEsLt K58-ac
HSP90A iso2 (human) NSSDALDKIRyESLT K180
HSP90A (mouse) NsSDALDKIRyEsLT K58
HSP90A (rat) NSSDALDkIRYESLT K58-ac
HSP90A (hamster) NSSDALDKIRYESLT K58
Y61-p
DALDkIRyEsLtDPS
0 63
HSP90A (human) DALDkIRyEsLtDPS Y61-p
HSP90A iso2 (human) DALDKIRyESLTDPS Y183-p
HSP90A (mouse) DALDkIRyEsLTDPS Y61-p
HSP90A (rat) DALDkIRYESLTDPS Y61
HSP90A (hamster) DALDKIRYESLTDPS Y61
S63-p
LDkIRyEsLtDPSkL
0 14
HSP90A (human) LDkIRyEsLtDPSkL S63-p
HSP90A iso2 (human) LDKIRyESLTDPSKL S185
HSP90A (mouse) LDkIRyEsLTDPSkL S63-p
HSP90A (rat) LDkIRYESLTDPSKL S63
HSP90A (hamster) LDKIRYESLTDPSKL S63
T65-p
kIRyEsLtDPSkLDS
0 3
HSP90A (human) kIRyEsLtDPSkLDS T65-p
HSP90A iso2 (human) KIRyESLTDPSKLDS T187
HSP90A (mouse) kIRyEsLTDPSkLDS T65
HSP90A (rat) kIRYESLTDPSKLDS T65
HSP90A (hamster) KIRYESLTDPSKLDS T65
K69-ac
EsLtDPSkLDSGkEL
Upstream
Downstream
3 7
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • exocytosis, induced
Treatment
  • LAQ824
  • LBH-589
  • siRNA
HSP90A (human) EsLtDPSkLDSGkEL K69-ac
HSP90A iso2 (human) ESLTDPSKLDSGkEL K191
HSP90A (mouse) EsLTDPSKLDSGkEL K69
HSP90A (rat) ESLTDPSKLDSGKEL K69
HSP90A (hamster) ESLTDPSKLDSGKEL K69
K69-ub
EsLtDPSkLDSGkEL
0 54
HSP90A (human) EsLtDPSkLDSGkEL K69-ub
HSP90A iso2 (human) ESLTDPSKLDSGkEL K191
HSP90A (mouse) EsLTDPSkLDSGkEL K69-ub
HSP90A (rat) ESLTDPSKLDSGKEL K69
HSP90A (hamster) ESLTDPSKLDSGKEL K69
K74-ac
PSkLDSGkELHINLI
0 3
HSP90A (human) PSkLDSGkELHINLI K74-ac
HSP90A iso2 (human) PSKLDSGkELHINLI K196-ac
HSP90A (mouse) PSkLDSGKELHINLI K74
HSP90A (rat) PSKLDSGKELHINLI K74
HSP90A (hamster) PSKLDSGKELHINII K74
K74-ub
PSkLDSGkELHINLI
0 38
HSP90A (human) PSkLDSGkELHINLI K74-ub
HSP90A iso2 (human) PSKLDSGKELHINLI K196
HSP90A (mouse) PSkLDSGkELHINLI K74-ub
HSP90A (rat) PSKLDSGKELHINLI K74
HSP90A (hamster) PSKLDSGKELHINII K74
K84-ub
HINLIPNkQDRtLtI
0 9
HSP90A (human) HINLIPNkQDRtLtI K84-ub
HSP90A iso2 (human) HINLIPNKQDRTLTI K206
HSP90A (mouse) HINLIPSkQDRTLTI K84-ub
HSP90A (rat) HINLIPNKQDRTLTI K84
HSP90A (hamster) HINIIPNKQDRTLTI K84
K84-ac
HINLIPNkQDRtLtI
0 3
HSP90A (human) HINLIPNkQDRtLtI K84-ac
HSP90A iso2 (human) HINLIPNKQDRTLTI K206
HSP90A (mouse) HINLIPSKQDRTLTI K84
HSP90A (rat) HINLIPNkQDRTLTI K84-ac
HSP90A (hamster) HINIIPNKQDRTLTI K84
T88-p
IPNkQDRtLtIVDTG
0 2
HSP90A (human) IPNkQDRtLtIVDTG T88-p
HSP90A iso2 (human) IPNKQDRTLTIVDTG T210
HSP90A (mouse) IPSkQDRTLTIVDTG T88
HSP90A (rat) IPNkQDRTLTIVDTG T88
HSP90A (hamster) IPNKQDRTLTIVDTG T88
T90-p
NkQDRtLtIVDTGIG
Upstream
Downstream
2 3
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, altered
  • exocytosis, altered
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Putative upstream phosphatases:
  • PPP5C (human)
Regulatory protein:
  • PKACA (human)
HSP90A (human) NkQDRtLtIVDTGIG T90-p
HSP90A iso2 (human) NKQDRTLTIVDTGIG T212
HSP90A (mouse) SkQDRTLTIVDTGIG T90
HSP90A (rat) NkQDRTLTIVDTGIG T90
HSP90A (hamster) NKQDRTLTIVDTGIG T90
T99-p
VDTGIGMtkADLINN
0 3
HSP90A (human) VDTGIGMtkADLINN T99-p
HSP90A iso2 (human) VDTGIGMTKADLINN T221
HSP90A (mouse) VDTGIGMTkADLINN T99
HSP90A (rat) VDTGIGMTkADLINN T99
HSP90A (hamster) VDTGIGMTKADLINN T99
K100-ac
DTGIGMtkADLINNL
Upstream
Downstream
1 3
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • exocytosis, induced
Treatment
  • LBH-589
  • siRNA
HSP90A (human) DTGIGMtkADLINNL K100-ac
HSP90A iso2 (human) DTGIGMTKADLINNL K222
HSP90A (mouse) DTGIGMTKADLINNL K100
HSP90A (rat) DTGIGMTkADLINNL K100-ac
HSP90A (hamster) DTGIGMTKADLINNL K100
K100-ub
DTGIGMtkADLINNL
0 36
HSP90A (human) DTGIGMtkADLINNL K100-ub
HSP90A iso2 (human) DTGIGMTKADLINNL K222
HSP90A (mouse) DTGIGMTkADLINNL K100-ub
HSP90A (rat) DTGIGMTKADLINNL K100
HSP90A (hamster) DTGIGMTKADLINNL K100
T109-p
DLINNLGtIAkSGtk
0 6
HSP90A (human) DLINNLGtIAkSGtk T109-p
HSP90A iso2 (human) DLINNLGTIAKSGTK T231
HSP90A (mouse) DLINNLGtIAkSGTk T109-p
HSP90A (rat) DLINNLGTIAkSGTK T109
HSP90A (hamster) DLINNLGTIAKSGTK T109
K112-ub
NNLGtIAkSGtkAFM
0 90
HSP90A (human) NNLGtIAkSGtkAFM K112-ub
HSP90A iso2 (human) NNLGTIAKSGTKAFM K234
HSP90A (mouse) NNLGtIAkSGTkAFM K112-ub
HSP90A (rat) NNLGTIAkSGTKAFM K112-ub
HSP90A (hamster) NNLGTIAKSGTKAFM K112
T115-p
GtIAkSGtkAFMEAL
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PKCG (human)
  • TTK (human)
Putative in vivo kinases:
  • PKCG (human)
HSP90A (human) GtIAkSGtkAFMEAL T115-p
HSP90A iso2 (human) GTIAKSGTKAFMEAL T237
HSP90A (mouse) GtIAkSGTkAFMEAL T115
HSP90A (rat) GTIAkSGTKAFMEAL T115
HSP90A (hamster) GTIAKSGTKAFMEAL T115
K116-ub
tIAkSGtkAFMEALQ
0 14
HSP90A (human) tIAkSGtkAFMEALQ K116-ub
HSP90A iso2 (human) TIAKSGTKAFMEALQ K238
HSP90A (mouse) tIAkSGTkAFMEALQ K116-ub
HSP90A (rat) TIAkSGTKAFMEALQ K116
HSP90A (hamster) TIAKSGTKAFMEALQ K116
K153-ub
EKVTVITkHNDDEQy
0 9
HSP90A (human) EKVTVITkHNDDEQy K153-ub
HSP90A iso2 (human) EKVTVITKHNDDEQY K275
HSP90A (mouse) EKVTVITKHNDDEQY K153
HSP90A (rat) EKVTVITKHNDDEQY K153
HSP90A (hamster) EKVTVITKHNDDEQY K153
Y160-p
kHNDDEQyAWEsSAG
0 3
HSP90A (human) kHNDDEQyAWEsSAG Y160-p
HSP90A iso2 (human) KHNDDEQYAWESSAG Y282
HSP90A (mouse) KHNDDEQYAWESSAG Y160
HSP90A (rat) KHNDDEQYAWESSAG Y160
HSP90A (hamster) KHNDDEQYAWESSAG Y160
S164-p
DEQyAWEsSAGGSFT
0 1
HSP90A (human) DEQyAWEsSAGGSFT S164-p
HSP90A iso2 (human) DEQYAWESSAGGSFT S286
HSP90A (mouse) DEQYAWESSAGGSFT S164
HSP90A (rat) DEQYAWESSAGGSFT S164
HSP90A (hamster) DEQYAWESSAGGSFT S164
K185-ub
EPMGRGTkVILHLkE
0 55
HSP90A (human) EPMGRGTkVILHLkE K185-ub
HSP90A iso2 (human) EPMGRGTKVILHLKE K307
HSP90A (mouse) EPMGRGTkVILHLkE K185-ub
HSP90A (rat) EPMGRGTKVILHLkE K185
HSP90A (hamster) EPMGRGTKVILHLKE K185
K191-ub
TkVILHLkEDQtEyL
0 79
HSP90A (human) TkVILHLkEDQtEyL K191-ub
HSP90A iso2 (human) TKVILHLKEDQTEYL K313
HSP90A (mouse) TkVILHLkEDQTEyL K191-ub
HSP90A (rat) TKVILHLKEDQTEyL K191
HSP90A (hamster) TKVILHLKEDQTEYM K191
K191-ac
TkVILHLkEDQtEyL
Upstream
1 6
Regulatory protein:
  • HDAC6 (human)
HSP90A (human) TkVILHLkEDQtEyL K191-ac
HSP90A iso2 (human) TKVILHLKEDQTEYL K313
HSP90A (mouse) TkVILHLKEDQTEyL K191
HSP90A (rat) TKVILHLkEDQTEyL K191-ac
HSP90A (hamster) TKVILHLKEDQTEYM K191
K191-sm
TkVILHLkEDQtEyL
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
HSP90A (human) TkVILHLkEDQtEyL K191-sm
HSP90A iso2 (human) TKVILHLKEDQTEYL K313
HSP90A (mouse) TkVILHLKEDQTEyL K191
HSP90A (rat) TKVILHLKEDQTEyL K191
HSP90A (hamster) TKVILHLKEDQTEYM K191
T195-p
LHLkEDQtEyLEERR
0 11
HSP90A (human) LHLkEDQtEyLEERR T195-p
HSP90A iso2 (human) LHLKEDQTEYLEERR T317
HSP90A (mouse) LHLkEDQTEyLEERR T195
HSP90A (rat) LHLkEDQTEyLEERR T195
HSP90A (hamster) LHLKEDQTEYMEERR T195
Y197-p
LkEDQtEyLEERRIk
Upstream
Downstream
2 184
Effects on Modified Protein
  • molecular association, regulation
  • protein conformation
Kinase, in vitro:
  • Src (human)
Treatment
  • geldanamycin
  • ionomycin
  • phorbol_ester
  • PU-H71
HSP90A (human) LkEDQtEyLEERRIk Y197-p
HSP90A iso2 (human) LKEDQTEYLEERRIK Y319
HSP90A (mouse) LkEDQTEyLEERRIK Y197-p
HSP90A (rat) LkEDQTEyLEERRIk Y197-p
HSP90A (hamster) LKEDQTEYMEERRIK Y197
K204
yLEERRIKEIVKkHs
0 1
HSP90A (human) yLEERRIKEIVKkHs K204
HSP90A iso2 (human) YLEERRIKEIVKKHS K326
HSP90A (mouse) yLEERRIKEIVKKHs K204
HSP90A (rat) yLEERRIkEIVkKHs K204-ac
HSP90A (hamster) YMEERRIKEIVKKHS K204
K204-ub
yLEERRIkEIVKkHs
0 1
HSP90A (human) yLEERRIkEIVKkHs K204-ub
HSP90A iso2 (human) YLEERRIKEIVKKHS K326
HSP90A (mouse) yLEERRIKEIVKKHs K204
HSP90A (rat) yLEERRIKEIVkKHs K204
HSP90A (hamster) YMEERRIKEIVKKHS K204
K208
RRIkEIVKkHsQFIG
0 1
HSP90A (human) RRIkEIVKkHsQFIG K208
HSP90A iso2 (human) RRIKEIVKKHSQFIG K330
HSP90A (mouse) RRIKEIVKKHsQFIG K208
HSP90A (rat) RRIkEIVkKHsQFIG K208-ac
HSP90A (hamster) RRIKEIVKKHSQFIG K208
K209-ub
RIkEIVKkHsQFIGy
0 4
HSP90A (human) RIkEIVKkHsQFIGy K209-ub
HSP90A iso2 (human) RIKEIVKKHSQFIGY K331
HSP90A (mouse) RIKEIVKKHsQFIGY K209
HSP90A (rat) RIkEIVkKHsQFIGY K209
HSP90A (hamster) RIKEIVKKHSQFIGY K209
S211-p
kEIVKkHsQFIGyPI
0 5
HSP90A (human) kEIVKkHsQFIGyPI S211-p
HSP90A iso2 (human) KEIVKKHSQFIGYPI S333
HSP90A (mouse) KEIVKKHsQFIGYPI S211-p
HSP90A (rat) kEIVkKHsQFIGYPI S211-p
HSP90A (hamster) KEIVKKHSQFIGYPI S211
Y216-p
kHsQFIGyPItLFVE
0 1
HSP90A (human) kHsQFIGyPItLFVE Y216-p
HSP90A iso2 (human) KHSQFIGYPITLFVE Y338
HSP90A (mouse) KHsQFIGYPITLFVE Y216
HSP90A (rat) KHsQFIGYPITLFVE Y216
HSP90A (hamster) KHSQFIGYPITLFVE Y216
T219-p
QFIGyPItLFVEkER
0 1
HSP90A (human) QFIGyPItLFVEkER T219-p
HSP90A iso2 (human) QFIGYPITLFVEKER T341
HSP90A (mouse) QFIGYPITLFVEkER T219
HSP90A (rat) QFIGYPITLFVEKER T219
HSP90A (hamster) QFIGYPITLFVEKER T219
K224-ac
PItLFVEkERDkEVs
0 4
HSP90A (human) PItLFVEkERDkEVs K224-ac
HSP90A iso2 (human) PITLFVEKERDKEVS K346
HSP90A (mouse) PITLFVEKERDKEVs K224
HSP90A (rat) PITLFVEKERDKEVs K224
HSP90A (hamster) PITLFVEKERDKEVs K224
K224-ub
PItLFVEkERDkEVs
0 8
HSP90A (human) PItLFVEkERDkEVs K224-ub
HSP90A iso2 (human) PITLFVEKERDKEVS K346
HSP90A (mouse) PITLFVEkERDKEVs K224-ub
HSP90A (rat) PITLFVEKERDKEVs K224
HSP90A (hamster) PITLFVEKERDKEVs K224
K228-ub
FVEkERDkEVsDDEA
0 1
HSP90A (human) FVEkERDkEVsDDEA K228-ub
HSP90A iso2 (human) FVEKERDKEVSDDEA K350
HSP90A (mouse) FVEkERDKEVsDDEA K228
HSP90A (rat) FVEKERDKEVsDDEA K228
HSP90A (hamster) FVEKERDKEVsDDEA K228
S231-p
kERDkEVsDDEAEEk
Upstream
3 92
Regulatory protein:
  • PRP4 (human)
  • TEBP (human)
Treatment
  • EGF
  • MG132_withdrawal
HSP90A (human) kERDkEVsDDEAEEk S231-p
HSP90A iso2 (human) KERDKEVSDDEAEEK S353
HSP90A (mouse) kERDKEVsDDEAEEK S231-p
HSP90A (rat) KERDKEVsDDEAEEK S231-p
HSP90A (hamster) KERDKEVsDDEAEEK S231-p
K238-ub
sDDEAEEkEDKEEEK
0 1
HSP90A (human) sDDEAEEkEDKEEEK K238-ub
HSP90A iso2 (human) SDDEAEEKEDKEEEK K360
HSP90A (mouse) sDDEAEEKEEKEEEK K238
HSP90A (rat) sDDEAEEKEEKEEEK K238
HSP90A (hamster) sDDEAEEKEDKEEEK K238
S252-p
KEKEEKEsEDkPEIE
0 27
HSP90A (human) KEKEEKEsEDkPEIE S252-p
HSP90A iso2 (human) KEKEEKESEDKPEIE S374
HSP90A (mouse) KEKEEKEsDDKPEIE S252-p
HSP90A (rat) KEKEEKEsDDKPEIE S252-p
HSP90A (hamster) KEKEEKGIDDKPEIE I252
K255-ub
EEKEsEDkPEIEDVG
0 1
HSP90A (human) EEKEsEDkPEIEDVG K255-ub
HSP90A iso2 (human) EEKESEDKPEIEDVG K377
HSP90A (mouse) EEKEsDDKPEIEDVG K255
HSP90A (rat) EEKEsDDKPEIEDVG K255
HSP90A (hamster) EEKGIDDKPEIEDVG K255
S263-p
PEIEDVGsDEEEEKK
Upstream
3 259
Kinase, in vitro:
  • CK2A1 (human)
  • CK2A1 (rabbit)
Regulatory protein:
  • TEBP (human)
Treatment
  • BI_4834
  • EGF
  • metastatic potential
  • nocodazole
  • U0126
HSP90A (human) PEIEDVGsDEEEEKK S263-p
HSP90A iso2 (human) PEIEDVGSDEEEEKK S385
HSP90A (mouse) PEIEDVGsDEEEEEK S263-p
HSP90A (rat) PEIEDVGsDEEEEEK S263-p
HSP90A (hamster) PEIEDVGSDEEEEEK S263
K274-ac
EEKKDGDkKKKKKIk
0 2
HSP90A (human) EEKKDGDkKKKKKIk K274-ac
HSP90A iso2 (human) EEKKDGDKKKKKKIK K396
HSP90A (mouse) EEKKDGDkkKKKKIK K275-ac
HSP90A (rat) EEKKDGDKKKKKKIK K275
HSP90A (hamster) EEKKDGDKKKKKKIK K275
K275
EKKDGDkKKKKKIkE
0 1
HSP90A (human) EKKDGDkKKKKKIkE K275
HSP90A iso2 (human) EKKDGDKKKKKKIKE K397
HSP90A (mouse) EKKDGDkkKKKKIKE K276-ac
HSP90A (rat) EKKDGDKKKKKKIKE K276
HSP90A (hamster) EKKDGDKKKKKKIKE K276
K281-ub
kKKKKKIkEkyIDQE
0 2
HSP90A (human) kKKKKKIkEkyIDQE K281-ub
HSP90A iso2 (human) KKKKKKIKEKyIDQE K403
HSP90A (mouse) kkKKKKIKEkyIDQE K282
HSP90A (rat) KKKKKKIKEkYIDQE K282
HSP90A (hamster) KKKKKKIKEKYIDQE K282
K283-ac
KKKKIkEkyIDQEEL
Upstream
1 25
Regulatory protein:
  • HDAC6 (human)
Treatment
  • vorinostat
HSP90A (human) KKKKIkEkyIDQEEL K283-ac
HSP90A iso2 (human) KKKKIKEKyIDQEEL K405
HSP90A (mouse) KKKKIKEkyIDQEEL K284-ac
HSP90A (rat) KKKKIKEkYIDQEEL K284-ac
HSP90A (hamster) KKKKIKEKYIDQEEL K284
K283-ub
KKKKIkEkyIDQEEL
0 29
HSP90A (human) KKKKIkEkyIDQEEL K283-ub
HSP90A iso2 (human) KKKKIKEKyIDQEEL K405
HSP90A (mouse) KKKKIKEkyIDQEEL K284-ub
HSP90A (rat) KKKKIKEKYIDQEEL K284
HSP90A (hamster) KKKKIKEKYIDQEEL K284
Y284-p
KKKIkEkyIDQEELN
Upstream
0 143
Treatment
  • BI2536
  • gefitinib
HSP90A (human) KKKIkEkyIDQEELN Y284-p
HSP90A iso2 (human) KKKIKEKyIDQEELN Y406-p
HSP90A (mouse) KKKIKEkyIDQEELN Y285-p
HSP90A (rat) KKKIKEkYIDQEELN Y285
HSP90A (hamster) KKKIKEKYIDQEELN Y285
K292-ac
IDQEELNktkPIWTr
Upstream
Downstream
1 8
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • LBH-589
  • siRNA
  • vorinostat
HSP90A (human) IDQEELNktkPIWTr K292-ac
HSP90A iso2 (human) IDQEELNKTKPIWTR K414
HSP90A (mouse) IDQEELNktkPIWTR K293-ac
HSP90A (rat) IDQEELNkTkPIWTR K293-ac
HSP90A (hamster) IDQEELNKTKPIWTR K293
K292-ub
IDQEELNktkPIWTr
0 41
HSP90A (human) IDQEELNktkPIWTr K292-ub
HSP90A iso2 (human) IDQEELNKTKPIWTR K414
HSP90A (mouse) IDQEELNktkPIWTR K293-ub
HSP90A (rat) IDQEELNKTkPIWTR K293
HSP90A (hamster) IDQEELNKTKPIWTR K293
T293-p
DQEELNktkPIWTrN
0 10
HSP90A (human) DQEELNktkPIWTrN T293-p
HSP90A iso2 (human) DQEELNKTKPIWTRN T415
HSP90A (mouse) DQEELNktkPIWTRN T294-p
HSP90A (rat) DQEELNkTkPIWTRN T294
HSP90A (hamster) DQEELNKTKPIWTRN T294
K294-ac
QEELNktkPIWTrNP
Upstream
Downstream
4 3
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, induced
Regulatory protein:
  • HDAC6 (human)
  • SIRT2 (human)
Treatment
  • IL-1a
  • IL-6
  • LPS
  • TNF
HSP90A (human) QEELNktkPIWTrNP K294-ac
HSP90A iso2 (human) QEELNKTKPIWTRNP K416
HSP90A (mouse) QEELNktkPIWTRNP K295-ac
HSP90A (rat) QEELNkTkPIWTRNP K295-ac
HSP90A (hamster) QEELNKTKPIWTRNP K295
K294-ub
QEELNktkPIWTrNP
0 8
HSP90A (human) QEELNktkPIWTrNP K294-ub
HSP90A iso2 (human) QEELNKTKPIWTRNP K416
HSP90A (mouse) QEELNktkPIWTRNP K295-ub
HSP90A (rat) QEELNkTKPIWTRNP K295
HSP90A (hamster) QEELNKTKPIWTRNP K295
R299-m1
ktkPIWTrNPDDItN
0 2
HSP90A (human) ktkPIWTrNPDDItN R299-m1
HSP90A iso2 (human) KTKPIWTRNPDDITN R421
HSP90A (mouse) ktkPIWTRNPDDITN R300
HSP90A (rat) kTkPIWTRNPDDITN R300
HSP90A (hamster) KTKPIWTRNPDDITN R300
T305-p
TrNPDDItNEEyGEF
0 2
HSP90A (human) TrNPDDItNEEyGEF T305-p
HSP90A iso2 (human) TRNPDDITNEEYGEF T427
HSP90A (mouse) TRNPDDITNEEYGEF T306
HSP90A (rat) TRNPDDITNEEYGEF T306
HSP90A (hamster) TRNPDDITNEEYGEF T306
Y309-p
DDItNEEyGEFyksL
Upstream
Downstream
1 4
Effects on Modified Protein
  • protein conformation
Treatment
  • geldanamycin
  • PU-H71
HSP90A (human) DDItNEEyGEFyksL Y309-p
HSP90A iso2 (human) DDITNEEYGEFYKSL Y431
HSP90A (mouse) DDITNEEYGEFyksL Y310
HSP90A (rat) DDITNEEYGEFYKSL Y310
HSP90A (hamster) DDITNEEYGEFYKSL Y310
Y313-p
NEEyGEFyksLtNDW
Downstream
1 10
Effects on Modified Protein
  • molecular association, regulation
HSP90A (human) NEEyGEFyksLtNDW Y313-p
HSP90A iso2 (human) NEEYGEFYKSLTNDW Y435
HSP90A (mouse) NEEYGEFyksLTNDW Y314-p
HSP90A (rat) NEEYGEFYKSLTNDW Y314
HSP90A (hamster) NEEYGEFYKSLTNDW Y314
K314-ac
EEyGEFyksLtNDWE
0 2
HSP90A (human) EEyGEFyksLtNDWE K314-ac
HSP90A iso2 (human) EEYGEFYKSLTNDWE K436
HSP90A (mouse) EEYGEFyKsLTNDWE K315
HSP90A (rat) EEYGEFYKSLTNDWE K315
HSP90A (hamster) EEYGEFYKSLTNDWE K315
K314-ub
EEyGEFyksLtNDWE
0 11
HSP90A (human) EEyGEFyksLtNDWE K314-ub
HSP90A iso2 (human) EEYGEFYKSLTNDWE K436
HSP90A (mouse) EEYGEFyksLTNDWE K315-ub
HSP90A (rat) EEYGEFYKSLTNDWE K315
HSP90A (hamster) EEYGEFYKSLTNDWE K315
S315-p
EyGEFyksLtNDWED
0 21
HSP90A (human) EyGEFyksLtNDWED S315-p
HSP90A iso2 (human) EYGEFYKSLTNDWED S437
HSP90A (mouse) EYGEFyksLTNDWEE S316-p
HSP90A (rat) EYGEFYKSLTNDWEE S316
HSP90A (hamster) EYGEFYKSLTNDWEE S316
T317-p
GEFyksLtNDWEDHL
0 12
HSP90A (human) GEFyksLtNDWEDHL T317-p
HSP90A iso2 (human) GEFYKSLTNDWEDHL T439
HSP90A (mouse) GEFyksLTNDWEEHL T318
HSP90A (rat) GEFYKSLTNDWEEHL T318
HSP90A (hamster) GEFYKSLTNDWEEHL T318
K327-ac
WEDHLAVkHFSVEGQ
Upstream
Downstream
1 3
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • exocytosis, induced
Treatment
  • LBH-589
  • siRNA
HSP90A (human) WEDHLAVkHFSVEGQ K327-ac
HSP90A iso2 (human) WEDHLAVkHFSVEGQ K449-ac
HSP90A (mouse) WEEHLAVKHFSVEGQ K328
HSP90A (rat) WEEHLAVKHFSVEGQ K328
HSP90A (hamster) WEEHLAVKHFSVEGQ K328
K327-ub
WEDHLAVkHFSVEGQ
0 16
HSP90A (human) WEDHLAVkHFSVEGQ K327-ub
HSP90A iso2 (human) WEDHLAVKHFSVEGQ K449
HSP90A (mouse) WEEHLAVKHFSVEGQ K328
HSP90A (rat) WEEHLAVKHFSVEGQ K328
HSP90A (hamster) WEEHLAVKHFSVEGQ K328
R345-m1
RALLFVPrRAPFDLF
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
HSP90A (human) RALLFVPrRAPFDLF R345-m1
HSP90A iso2 (human) RALLFVPRRAPFDLF R467
HSP90A (mouse) RALLFVPRRAPFDLF R346
HSP90A (rat) RALLFVPRRAPFDLF R346
HSP90A (hamster) RALLFVPRRAPFDLF R346
R355-m1
PFDLFENrKkkNNIk
0 1
HSP90A (human) PFDLFENrKkkNNIk R355-m1
HSP90A iso2 (human) PFDLFENRKKKNNIK R477
HSP90A (mouse) PFDLFENRKKKNNIk R356
HSP90A (rat) PFDLFENRKKKNNIk R356
HSP90A (hamster) PFDLFENRKKKNNIK R356
K357-sm
DLFENrKkkNNIkLY
0 1
HSP90A (human) DLFENrKkkNNIkLY K357-sm
HSP90A iso2 (human) DLFENRKKKNNIKLY K479
HSP90A (mouse) DLFENRKKKNNIkLY K358
HSP90A (rat) DLFENRKKKNNIkLY K358
HSP90A (hamster) DLFENRKKKNNIKLY K358
K358-ub
LFENrKkkNNIkLYV
0 1
HSP90A (human) LFENrKkkNNIkLYV K358-ub
HSP90A iso2 (human) LFENRKKKNNIKLYV K480
HSP90A (mouse) LFENRKKKNNIkLYV K359
HSP90A (rat) LFENRKKKNNIkLYV K359
HSP90A (hamster) LFENRKKKNNIKLYV K359
K358-sm
LFENrKkkNNIkLYV
0 1
HSP90A (human) LFENrKkkNNIkLYV K358-sm
HSP90A iso2 (human) LFENRKKKNNIKLYV K480
HSP90A (mouse) LFENRKKKNNIkLYV K359
HSP90A (rat) LFENRKKKNNIkLYV K359
HSP90A (hamster) LFENRKKKNNIKLYV K359
K362-ub
rKkkNNIkLYVRRVF
0 34
HSP90A (human) rKkkNNIkLYVRRVF