Other Species / Isoforms
  GSK3A (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsGGGPsGG
Upstream
0 12
Treatment
  • insulin
GSK3A (human) ______MsGGGPsGG S2-p
GSK3A (mouse) ______MsGGGPsGG S2-p
GSK3A (rat) ______MsGGGPSGG S2-p
GSK3A (cow) ______MSGGAPSGG S2
S7-p
_MsGGGPsGGGPGGs
0 3
GSK3A (human) _MsGGGPsGGGPGGs S7-p
GSK3A (mouse) _MsGGGPsGGGPGGs S7-p
GSK3A (rat) _MsGGGPSGGGPGGS S7
GSK3A (cow) _MSGGAPSGGGPGGS S7
S14-p
sGGGPGGsGRARtss
0 3
GSK3A (human) sGGGPGGsGrARtss S14-p
GSK3A (mouse) sGGGPGGsGRARtss S14-p
GSK3A (rat) SGGGPGGSGRARtss S14
GSK3A (cow) SGGGPGGSGRARTSs S14
R16
GGPGGsGRARtssFA
0 1
GSK3A (human) GGPGGsGrARtssFA R16-m1
GSK3A (mouse) GGPGGsGRARtssFA R16
GSK3A (rat) GGPGGSGRARtssFA R16
GSK3A (cow) GGPGGSGRARTSsFA R16
T19-p
GGsGRARtssFAEPG
Upstream
1 78
Treatment
  • LPA
GSK3A (human) GGsGrARtssFAEPG T19-p
GSK3A (mouse) GGsGRARtssFAEPG T19-p
GSK3A (rat) GGSGRARtssFAEPG T19-p
GSK3A (cow) GGSGRARTSsFAEPG T19
S20-p
GsGRARtssFAEPGG
0 51
GSK3A (human) GsGrARtssFAEPGG S20-p
GSK3A (mouse) GsGRARtssFAEPGG S20-p
GSK3A (rat) GSGRARtssFAEPGG S20-p
GSK3A (cow) GSGRARTSsFAEPGG S20
S21-p
sGRARtssFAEPGGG
Upstream
Downstream
135 296
GSK3A (human)
S21-p
GSK3A (mouse)
S21-p
GSK3A (rat)
S21-p
GSK3A (cow)
S21-p
Effects on Modified Protein
  • enzymatic activity, inhibited
  • protein degradation
Effects on Biological Processes:
  • apoptosis, induced
  • cell growth, altered
  • cell motility, induced
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
Kinase, in vitro:
  • Akt1 (mouse)
Putative in vivo kinases:
  • PKCA (human)
  • PKCB (human)
  • PKCH (human)
Regulatory protein:
  • Akt1 (human)
  • Akt1 (mouse)
  • Akt2 (mouse)
  • GRK2 (mouse)
  • ITGB1 (human)
  • PDK1 (mouse)
  • PIK3CG (human)
  • PLCB2 (human)
  • RICTOR (human)
  • RICTOR (mouse)
  • RPS23 (mouse)
  • Sin1 (mouse)
  • TSC1 (mouse)
  • TSC2 (mouse)
Treatment
  • 8-Rp-cAMP
  • A-443654
  • Akt-I-1
  • Akt_inhibitor_VIII
  • antichymotrypsin
  • BI-D1870
  • blood pressure
  • culturing_of_cells
  • fasting
  • fMLP
  • GF109203X
  • GSK-3_inhibitor_X
  • high-fat diet
  • IGF-1
  • IL-3
  • insulin
  • isoproterenol
  • L803-mts
  • lithium
  • LPA
  • LPS
  • LY294002
  • memantine
  • MK-2206
  • MK-591
  • muscle contraction
  • PDGF
  • phorbol_ester
  • physostigmine
  • pilocarpine
  • pregnancy
  • rapamycin
  • refeeding
  • Ro31-8220
  • serum
  • serum_starvation
  • siRNA
  • SL0101
  • U0126
  • wortmannin
GSK3A (human) sGrARtssFAEPGGG S21-p
GSK3A (mouse) sGRARtssFAEPGGG S21-p
GSK3A (rat) SGRARtssFAEPGGG S21-p
GSK3A (cow) SGRARTSsFAEPGGG S21-p
S39-p
GGGGPGGsAsGPGGT
0 8
GSK3A (human) GGGGPGGsAsGPGGt S39-p
GSK3A (mouse) GGGGPGGsAsGPGGT S39-p
GSK3A (rat) GGGGPGGSASGPGGT S39
GSK3A (cow) GGGGPGGSASGPGGS S39
S41-p
GGPGGsAsGPGGTGG
Upstream
0 7
Treatment
  • insulin
GSK3A (human) GGPGGsAsGPGGtGG S41-p
GSK3A (mouse) GGPGGsAsGPGGTGG S41-p
GSK3A (rat) GGPGGSASGPGGTGG S41
GSK3A (cow) GGPGGSASGPGGSGG S41
T46
sAsGPGGTGGGKASV
0 4
GSK3A (human) sAsGPGGtGGGKAsV T46-p
GSK3A (mouse) sAsGPGGTGGGKASV T46
GSK3A (rat) SASGPGGTGGGKASV T46
GSK3A (cow) SASGPGGSGGGKTSV S46
S52
GTGGGKASVGAMGGG
0 2
GSK3A (human) GtGGGKAsVGAMGGG S52-p
GSK3A (mouse) GTGGGKASVGAMGGG S52
GSK3A (rat) GTGGGKASVGAMGGG S52
GSK3A (cow) GSGGGKTSVGAMGGG S52
S63
MGGGVGASSSGGGPS
0 3
GSK3A (human) MGGGVGAsSSGGGPG S63-p
GSK3A (mouse) MGGGVGASSSGGGPS S63
GSK3A (rat) MGGGVGASSSGGGPS S63
GSK3A (cow) MGGGVGASSSGGGPG S63
S72-p
SGGGPSGsGGGGsGG
0 2
GSK3A (human) SGGGPGGsGGGGsGG S72-p
GSK3A (mouse) SGGGPSGsGGGGsGG S72-p
GSK3A (rat) SGGGPSGSGGGGSGG S72
GSK3A (cow) SGGGPGGSGGGGSGG S72
S77-p
SGsGGGGsGGPGAGt
0 2
GSK3A (human) GGsGGGGsGGPGAGT S77-p
GSK3A (mouse) SGsGGGGsGGPGAGt S77-p
GSK3A (rat) SGSGGGGSGGPGAGT S77
GSK3A (cow) GGSGGGGSGGPGAGT S77
T84-p
sGGPGAGtsFPPPGV
0 1
GSK3A (human) sGGPGAGTSFPPPGV T84
GSK3A (mouse) sGGPGAGtsFPPPGV T84-p
GSK3A (rat) SGGPGAGTSFPPPGV T84
GSK3A (cow) SGGPGAGTSFPPPGV T84
S85-p
GGPGAGtsFPPPGVK
0 1
GSK3A (human) GGPGAGTSFPPPGVK S85
GSK3A (mouse) GGPGAGtsFPPPGVK S85-p
GSK3A (rat) GGPGAGTSFPPPGVK S85
GSK3A (cow) GGPGAGTSFPPPGVK S85
S97
GVKLGRDSGKVTTVV
0 3
GSK3A (human) GVKLGRDsGKVTTVV S97-p
GSK3A (mouse) GVKLGRDSGKVTTVV S97
GSK3A (rat) GVKLGRDSGKVTTVV S97
GSK3A (cow) GVKLGRDSGKVTTVV S97
K123
EVAYTDIKVIGNGSF
0 1
GSK3A (human) EVAYTDIkVIGNGSF K123-ac
GSK3A (mouse) EVAYTDIKVIGNGSF K123
GSK3A (rat) EVAYTDIKVIGNGSF K123
GSK3A (cow) EVAYTDIKVIGSGSF K123
Y134-p
NGSFGVVyQARLAET
0 26
GSK3A (human) NGSFGVVyQARLAEt Y134-p
GSK3A (mouse) NGSFGVVyQARLAET Y134-p
GSK3A (rat) NGSFGVVyQARLAET Y134-p
GSK3A (cow) SGSFGVVYQARLADT Y134
T141
yQARLAETRELVAIK
0 1
GSK3A (human) yQARLAEtRELVAIK T141-p
GSK3A (mouse) yQARLAETRELVAIK T141
GSK3A (rat) yQARLAETRELVAIK T141
GSK3A (cow) YQARLADTRELVAIK T141
Y197
YLNLVLEYVPETVYR
0 3
GSK3A (human) YLNLVLEyVPETVYR Y197-p
GSK3A (mouse) YLNLVLEYVPETVYR Y197
GSK3A (rat) YLNLVLEYVPETVYR Y197
GSK3A (cow) YLNLVLEYVPETVYR Y197
K246
GVCHRDIKPQNLLVD
0 1
GSK3A (human) GVCHRDIkPQNLLVD K246-ub
GSK3A (mouse) GVCHRDIKPQNLLVD K246
GSK3A (rat) GVCHRDIKPQNLLVD K246
GSK3A (cow) GVCHRDIKPQNLLVD K246
K260
DPDTAVLKLCDFGSA
0 1
GSK3A (human) DPDTAVLkLCDFGSA K260-ub
GSK3A (mouse) DPDTAVLKLCDFGSA K260
GSK3A (rat) DPDTAVLKLCDFGSA K260
GSK3A (cow) DPDTAVLKLCDFGSA K260
K268-ub
LCDFGSAkQLVRGEP
0 9
GSK3A (human) LCDFGSAkQLVRGEP K268-ub
GSK3A (mouse) LCDFGSAkQLVRGEP K268-ub
GSK3A (rat) LCDFGSAKQLVRGEP K268
GSK3A (cow) LCDFGSAKQLVRGEP K268
S278-p
VRGEPNVsyICsRYY
Upstream
1 1286
Regulatory protein:
  • RICTOR (mouse)
GSK3A (human) VRGEPNVsyICsRyy S278-p
GSK3A (mouse) VRGEPNVsyICsRYY S278-p
GSK3A (rat) VRGEPNVsyICsRyY S278-p
GSK3A (cow) VRGEPNVSYICSRYY S278
Y279-p
RGEPNVsyICsRYYR
Upstream
18 4311
Regulatory protein:
  • APP (human)
  • FCER1A (mouse)
  • RICTOR (mouse)
  • Src (mouse)
Treatment
  • memantine
  • physostigmine
  • pilocarpine
GSK3A (human) RGEPNVsyICsRyyR Y279-p
GSK3A (mouse) RGEPNVsyICsRYYR Y279-p
GSK3A (rat) RGEPNVsyICsRyYR Y279-p
GSK3A (cow) RGEPNVSYICSRYYR Y279
S282-p
PNVsyICsRYYRAPE
Upstream
0 1142
Regulatory protein:
  • FCER1A (mouse)
GSK3A (human) PNVsyICsRyyRAPE S282-p
GSK3A (mouse) PNVsyICsRYYRAPE S282-p
GSK3A (rat) PNVsyICsRyYRAPE S282-p
GSK3A (cow) PNVSYICSRYYRAPE S282
Y284
VsyICsRYYRAPELI
0 109
GSK3A (human) VsyICsRyyRAPELI Y284-p
GSK3A (mouse) VsyICsRYYRAPELI Y284
GSK3A (rat) VsyICsRyYRAPELI Y284-p
GSK3A (cow) VSYICSRYYRAPELI Y284
Y285
syICsRYYRAPELIF
0 6
GSK3A (human) syICsRyyRAPELIF Y285-p
GSK3A (mouse) syICsRYYRAPELIF Y285
GSK3A (rat) syICsRyYRAPELIF Y285
GSK3A (cow) SYICSRYYRAPELIF Y285
K355-ub
NPNYTEFkFPQIKAH
0 5
GSK3A (human) NPNYTEFkFPQIKAH K355-ub
GSK3A (mouse) NPNYTEFkFPQIKAH K355-ub
GSK3A (rat) NPNYTEFKFPQIKAH K355
GSK3A (cow) NPNYTEFKFPQIKAH K355
K366
IKAHPWTKVFKSSkT
0 1
GSK3A (human) IKAHPWTKVFKSRTP K366
GSK3A (mouse) IKAHPWTKVFKSSkT K366
GSK3A (rat) IKAHPWTkVFKSRTP K366-ac
GSK3A (cow) IKAHPWTKVFKSRTP K366
K366
IKAHPWTKVFKSSkT
0 2
GSK3A (human) IKAHPWTkVFKSRTP K366-ub
GSK3A (mouse) IKAHPWTKVFKSSkT K366
GSK3A (rat) IKAHPWTKVFKSRTP K366
GSK3A (cow) IKAHPWTKVFKSRTP K366
K372-ub
TKVFKSSkTPPEAIA
0 1
GSK3A (human) WTkVFKSRTPPEAIA R371
GSK3A (mouse) TKVFKSSkTPPEAIA K372-ub
GSK3A (rat) WTkVFKSRTPPEAIA R371
GSK3A (cow) WTKVFKSRTPPEAIA R371
A487
DATTATLASSS____
0 1
GSK3A (human) TDATPTLtNSS____ T480-p
GSK3A (mouse) DATTATLASSS____ A487
GSK3A (rat) PDATPTLTNSS____ T480
GSK3A (cow) TDNTATLPPGLHLLQ P480