Other Species / Isoforms
  CCNE1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S59-p
TARDQCGsQPWDNNA
0 1
CCNE1 (human) TARDQCGsQPWDNNA S59-p
CCNE1 (mouse) TVKSEDSSQPWDDNS S56
CCNE1 (rat) TVKSQDSSQPWDDDS S59
S73-p
AVCADPCsLIPtPDK
Upstream
1 0
Kinase, in vitro:
  • GSK3B (human)
CCNE1 (human) AVCADPCsLIPtPDK S73-p
CCNE1 (mouse) SACVDPCSFIPtPNK S70
CCNE1 (rat) SACVDPCSFIPTPNK S73
T77-p
DPCsLIPtPDKEDDD
Upstream
Downstream
8 1
CCNE1 (human)
T77-p
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • GSK3B (human)
Treatment
  • calyculin_A
  • seliciclib
CCNE1 (human) DPCsLIPtPDKEDDD T77-p
CCNE1 (mouse) DPCSFIPtPNKEEDN T74-p
CCNE1 (rat) DPCSFIPTPNKEEDN T77
S90-p
DDRVYPNsTCKPRII
1 0
CCNE1 (human) DDRVYPNsTCKPRII S90-p
CCNE1 (mouse) NELEYPRTAFQPRKI T88
CCNE1 (rat) NELEYPKTAFQPRKI T91
S103-p
IIAPSRGsPLPVLSW
1 11
CCNE1 (human) IIAPSRGsPLPVLSW S103-p
CCNE1 (mouse) KIRPPRAsPLPVLNW S101-p
CCNE1 (rat) KIRPPRASPLPVLNW S104
S381-p
RAKKAMLsEQNRAsP
0 2
CCNE1 (human) RAKKAMLsEQNRAsP S381-p
CCNE1 (mouse) QAKKAILSEQNRIsP S379
CCNE1 (rat) QAKKAILSEQNRISP S382
S387-p
LsEQNRAsPLPSGLL
Upstream
Downstream
2 16
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • CDK2 (human)
CCNE1 (human) LsEQNRAsPLPSGLL S387-p
CCNE1 (mouse) LSEQNRIsPPPsVVL S385-p
CCNE1 (rat) LSEQNRISPPPSGVL S388
S391
NRAsPLPSGLLtPPQ
0 1
CCNE1 (human) NRAsPLPSGLLtPPQ S391
CCNE1 (mouse) NRIsPPPsVVLtPPP S389-p
CCNE1 (rat) NRISPPPSGVLTPPH S392
T395-p
PLPSGLLtPPQsGKK
Upstream
Downstream
15 9
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK2 (human)
  • GSK3B (human)
Putative in vivo kinases:
  • CDK2 (human)
  • GSK3A (human)
  • GSK3B (human)
Treatment
  • calyculin_A
  • lithium
  • LY294002
  • seliciclib
CCNE1 (human) PLPSGLLtPPQsGKK T395-p
CCNE1 (mouse) PPPsVVLtPPPSSKK T393-p
CCNE1 (rat) PPPSGVLTPPHSSKK T396
S399-p
GLLtPPQsGKKQSSG
Upstream
Downstream
5 3
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK2 (human)
Phosphatases, in vitro:
  • PPP2R2A (human)
Putative in vivo kinases:
  • CDK1 (human)
  • CDK2 (human)
Putative upstream phosphatases:
  • PPP2R2A (human)
Treatment
  • calyculin_A
  • seliciclib
CCNE1 (human) GLLtPPQsGKKQSSG S399-p
CCNE1 (mouse) VVLtPPPSSKKQSSE S397
CCNE1 (rat) GVLTPPHSSKKQSSE S400