Other Species / Isoforms
  C/EBP-alpha (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S21-p
PMSSHLQsPPHAPSN
Upstream
Downstream
10 1
C/EBP-alpha (human)
S21-p
C/EBP-alpha (mouse)
S21-p
C/EBP-alpha (rat)
S21-p
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • CDK1 (mouse)
Treatment
  • insulin
  • streptozotocin
C/EBP-alpha (human) PMSSHLQsPPHAPSS S21-p
C/EBP-alpha (mouse) PMSSHLQsPPHAPSN S21-p
C/EBP-alpha (rat) PMSSHLQsPPHAPSN S21-p
K159
ALRPLVIKQEPREED
0 2
C/EBP-alpha (human) ALRPLVIkQEPREED K161-ac
C/EBP-alpha (mouse) ALRPLVIKQEPREED K159
C/EBP-alpha (rat) ALRPLVIkQEPREED K159-ac
K159
ALRPLVIKQEPREED
0 1
C/EBP-alpha (human) ALRPLVIkQEPREED K161-ub
C/EBP-alpha (mouse) ALRPLVIKQEPREED K159
C/EBP-alpha (rat) ALRPLVIKQEPREED K159
K159-sm
ALRPLVIkQEPREED
3 1
C/EBP-alpha (human) ALRPLVIkQEPREED K161-sm
C/EBP-alpha (mouse) ALRPLVIkQEPREED K159-sm
C/EBP-alpha (rat) ALRPLVIkQEPREED K159-sm
-
gap
1 0
C/EBP-alpha (human) PPPPPPPsHPHPHPP S190-p
C/EBP-alpha (mouse) gap -
C/EBP-alpha (rat) gap -
S193-p
PPPHPHAsPAHLAAP
Upstream
Downstream
13 0
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, altered
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell differentiation, induced
  • cell growth, altered
  • cell growth, induced
  • cell growth, inhibited
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
  • translation, induced
Kinase, in vitro:
  • CDK1 (mouse)
  • CDK4 (human)
  • CDK4 (mouse)
  • CDK6 (mouse)
Putative in vivo kinases:
  • CDK1 (mouse)
  • CDK4 (human)
  • CDK4 (mouse)
  • CDK6 (mouse)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • Insulin (human)
Treatment
  • DEN
  • development
  • fasting
  • glucose
  • high-fat diet
  • insulin
  • okadaic_acid
  • palbociclib
  • PD0332991
  • phenobarbital
  • wounding
C/EBP-alpha (human) sHPHPHPPPAHLAAP P197
C/EBP-alpha (mouse) PPPHPHAsPAHLAAP S193-p
C/EBP-alpha (rat) PPPHPHAsPAHLAAP S193-p
T222-p
HLQPGHPtPPPtPVP
Upstream
Downstream
8 0
C/EBP-alpha (human)
T226-p
C/EBP-alpha (mouse)
T222-p
C/EBP-alpha (rat)
T222-p
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • GSK3A (human)
Putative in vivo kinases:
  • GSK3A (human)
Regulatory protein:
  • DISC1 (mouse)
Treatment
  • fasting
  • glucose
  • insulin
  • lithium
  • okadaic_acid
  • siRNA
  • streptozotocin
  • wortmannin
C/EBP-alpha (human) HLQPGHPTPPPTPVP T226
C/EBP-alpha (mouse) HLQPGHPtPPPtPVP T222-p
C/EBP-alpha (rat) HLQPGHPtPPPtPVP T222-p
T226-p
GHPtPPPtPVPsPHA
Upstream
Downstream
8 0
C/EBP-alpha (human)
T230-p
C/EBP-alpha (mouse)
T226-p
C/EBP-alpha (rat)
T226-p
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • GSK3A (human)
Putative in vivo kinases:
  • GSK3A (human)
Regulatory protein:
  • DISC1 (mouse)
Treatment
  • fasting
  • glucose
  • insulin
  • lithium
  • okadaic_acid
  • siRNA
  • streptozotocin
  • wortmannin
C/EBP-alpha (human) GHPTPPPTPVPsPHP T230
C/EBP-alpha (mouse) GHPtPPPtPVPsPHA T226-p
C/EBP-alpha (rat) GHPtPPPtPVPsPHP T226-p
S230-p
PPPtPVPsPHAAPAL
4 0
C/EBP-alpha (human) PPPTPVPsPHPAPAL S234-p
C/EBP-alpha (mouse) PPPtPVPsPHAAPAL S230-p
C/EBP-alpha (rat) PPPtPVPsPHPAPAM S230-p
A248
GLPGPGSALKGLAGA
4 0
C/EBP-alpha (human) GLPGPGSALKGLGAA A252
C/EBP-alpha (mouse) GLPGPGSALKGLAGA A248
C/EBP-alpha (rat) GLPGPGGsLKGLAGP S248-p
G262
AHPDLRTGGGGGGSG
0 1
C/EBP-alpha (human) AHPDLRAsGGSGAGK S266-p
C/EBP-alpha (mouse) AHPDLRTGGGGGGSG G262
C/EBP-alpha (rat) PHPDLRTGGGGGGGA G262
K299
RNNIAVRKSRDKAKQ
1 0
C/EBP-alpha (human) RNNIAVRkSRDkAKQ K298-ac
C/EBP-alpha (mouse) RNNIAVRKSRDKAKQ K299
C/EBP-alpha (rat) RNNIAVRKSRDKAKQ K298
K303
AVRKSRDKAKQRNVE
1 0
C/EBP-alpha (human) AVRkSRDkAKQRNVE K302-ac
C/EBP-alpha (mouse) AVRKSRDKAKQRNVE K303
C/EBP-alpha (rat) AVRKSRDKAKQRNVE K302
K314
RNVETQQKVLELTSD
0 1
C/EBP-alpha (human) RNVETQQkVLELTSD K313-ub
C/EBP-alpha (mouse) RNVETQQKVLELTSD K314
C/EBP-alpha (rat) RNVETQQKVLELTSD K313
K327
SDNDRLRKRVEQLSR
1 0
C/EBP-alpha (human) SDNDRLRkRVEQLsR K326-ac
C/EBP-alpha (mouse) SDNDRLRKRVEQLSR K327
C/EBP-alpha (rat) SDNDRLRKRVEQLSR K326
S333
RKRVEQLSRELDTLR
0 1
C/EBP-alpha (human) RkRVEQLsRELDTLR S332-p
C/EBP-alpha (mouse) RKRVEQLSRELDTLR S333
C/EBP-alpha (rat) RKRVEQLSRELDTLR S332