Other Species / Isoforms
  PRKD1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y93-p
KFPECGFyGLYDKIL
Upstream
3 0
Treatment
  • MitoQ
PRKD1 (human) KFPECGFyGMYDKIL Y95-p
PRKD1 (mouse) KFPECGFyGLYDKIL Y93-p
PRKD1 (rat) KFPECGFYGLYDKIL Y93
S203-p
GVRRRRLsNVsLTGL
Upstream
Downstream
7 119
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • P38D (human)
  • PKACA (human)
  • PRKD1 (mouse)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • insulin
  • phorbol_ester
PRKD1 (human) GVRRRRLsNVsLtGV S205-p
PRKD1 (mouse) GVRRRRLsNVsLTGL S203-p
PRKD1 (rat) GVRRRRLsNVsLTGL S203-p
S206-p
RRRLsNVsLTGLGtV
Upstream
2 34
Kinase, in vitro:
  • P38D (human)
Treatment
  • insulin
PRKD1 (human) RRRLsNVsLtGVSTI S208-p
PRKD1 (mouse) RRRLsNVsLTGLGtV S206-p
PRKD1 (rat) RRRLsNVsLTGLGTV S206-p
T208
RLsNVsLTGLGtVRT
0 8
PRKD1 (human) RLsNVsLtGVSTIRt T210-p
PRKD1 (mouse) RLsNVsLTGLGtVRT T208
PRKD1 (rat) RLsNVsLTGLGTVRT T208
T212-p
VsLTGLGtVRTASAE
0 1
PRKD1 (human) VsLtGVSTIRtSsAE T214
PRKD1 (mouse) VsLTGLGtVRTASAE T212-p
PRKD1 (rat) VsLTGLGTVRTASAE T212
T215
TGLGtVRTASAEFST
0 5
PRKD1 (human) tGVSTIRtSsAELst T217-p
PRKD1 (mouse) TGLGtVRTASAEFST T215
PRKD1 (rat) TGLGTVRTASAEFST T215
S217
LGtVRTASAEFSTSV
1 2
PRKD1 (human) VSTIRtSsAELstsA S219-p
PRKD1 (mouse) LGtVRTASAEFSTSV S217
PRKD1 (rat) LGTVRTASAEFSTSA S217
S221
RTASAEFSTSVPDEP
1 0
PRKD1 (human) RtSsAELstsAPDEP S223-p
PRKD1 (mouse) RTASAEFSTSVPDEP S221
PRKD1 (rat) RTASAEFSTSAPDEP S221
T222
TASAEFSTSVPDEPL
0 1
PRKD1 (human) tSsAELstsAPDEPL T224-p
PRKD1 (mouse) TASAEFSTSVPDEPL T222
PRKD1 (rat) TASAEFSTSAPDEPL T222
S223
ASAEFSTSVPDEPLL
0 1
PRKD1 (human) SsAELstsAPDEPLL S225-p
PRKD1 (mouse) ASAEFSTSVPDEPLL S223
PRKD1 (rat) ASAEFSTSAPDEPLL S223
S241-p
SPGFEQKsPsESFIG
0 8
PRKD1 (human) DEPLLQKsPsEsFIG S235-p
PRKD1 (mouse) SPGFEQKsPsESFIG S241-p
PRKD1 (rat) SPGFEQKSPSESFIG S241
S243-p
GFEQKsPsESFIGRE
0 9
PRKD1 (human) PLLQKsPsEsFIGRE S237-p
PRKD1 (mouse) GFEQKsPsESFIGRE S243-p
PRKD1 (rat) GFEQKSPSESFIGRE S243
S245
EQKsPsESFIGREKR
0 1
PRKD1 (human) LQKsPsEsFIGREKR S239-p
PRKD1 (mouse) EQKsPsESFIGREKR S245
PRKD1 (rat) EQKSPSESFIGREKR S245
S253-p
FIGREKRsNsQSYIG
0 3
PRKD1 (human) FIGREKRsNsQSYIG S247-p
PRKD1 (mouse) FIGREKRsNsQSYIG S253-p
PRKD1 (rat) FIGREKRSNSQSYVG S253
S255-p
GREKRsNsQSYIGRP
Upstream
2 15
Kinase, in vitro:
  • P38D (human)
Treatment
  • phorbol_ester
PRKD1 (human) GREKRsNsQSYIGRP S249-p
PRKD1 (mouse) GREKRsNsQSYIGRP S255-p
PRKD1 (rat) GREKRSNSQSYVGRP S255
K298-ub
QFCKKLLkGLFRQGL
0 2
PRKD1 (human) QYCKKLLkGLFRQGL K292-ub
PRKD1 (mouse) QFCKKLLkGLFRQGL K298-ub
PRKD1 (rat) QFCKKLLKGLFRQGL K298
S351
DVVMEEGSDDNDSER
0 1
PRKD1 (human) DVVMEEGsDDNDSER S345-p
PRKD1 (mouse) DVVMEEGSDDNDSER S351
PRKD1 (rat) DVVMEEGSDDNDSER S351
G385
LAEGQSGGAEMQDPD
0 1
PRKD1 (human) MAECQNDsGEMQDPD S379-p
PRKD1 (mouse) LAEGQSGGAEMQDPD G385
PRKD1 (rat) LAEGQSDGAEMQDPD G385
T401-p
DQEDSNRtIsPStsN
0 6
PRKD1 (human) DHEDANRtIsPStsN T395-p
PRKD1 (mouse) DQEDSNRtIsPStsN T401-p
PRKD1 (rat) DQEDSNRTIsPSTSN T401
S403-p
EDSNRtIsPStsNNI
Upstream
Downstream
1 38
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • P38D (human)
PRKD1 (human) EDANRtIsPStsNNI S397-p
PRKD1 (mouse) EDSNRtIsPStsNNI S403-p
PRKD1 (rat) EDSNRTIsPSTSNNI S403-p
T406-p
NRtIsPStsNNIPLM
0 3
PRKD1 (human) NRtIsPStsNNIPLM T400-p
PRKD1 (mouse) NRtIsPStsNNIPLM T406-p
PRKD1 (rat) NRTIsPSTSNNIPLM T406
S407-p
RtIsPStsNNIPLMR
Upstream
Downstream
1 21
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • P38D (human)
Treatment
  • insulin
  • LY294002
  • MK-2206
PRKD1 (human) RtIsPStsNNIPLMR S401-p
PRKD1 (mouse) RtIsPStsNNIPLMR S407-p
PRKD1 (rat) RTIsPSTSNNIPLMR S407
S418
PLMRVVQSVKHTKRR
1 1
PRKD1 (human) PLMRVVQsVKHTKRK S412-p
PRKD1 (mouse) PLMRVVQSVKHTKRR S418
PRKD1 (rat) PLMRVVQSVKHTKRR S418
S427-p
KHTKRRSsTVMKEGW
Upstream
Downstream
2 4
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
Effects on Biological Processes:
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
PRKD1 (human) KHTKRKSstVMKEGW S421-p
PRKD1 (mouse) KHTKRRSsTVMKEGW S427-p
PRKD1 (rat) KHTKRRSSTVMKEGW S427
T428
HTKRRSsTVMKEGWM
0 2
PRKD1 (human) HTKRKSstVMKEGWM T422-p
PRKD1 (mouse) HTKRRSsTVMKEGWM T428
PRKD1 (rat) HTKRRSSTVMKEGWM T428
Y438
KEGWMVHYTSKDTLR
1 1
PRKD1 (human) KEGWMVHyTSKDTLR Y432-p
PRKD1 (mouse) KEGWMVHYTSKDTLR Y438
PRKD1 (rat) KEGWMVHYTSKDTLR Y438
Y449
DTLRKRHYWRLDSKC
0 1
PRKD1 (human) DTLRKRHyWRLDsKC Y443-p
PRKD1 (mouse) DTLRKRHYWRLDSKC Y449
PRKD1 (rat) DTLRKRHYWRLDSKS Y449
S454
RHYWRLDSKCITLFQ
0 1
PRKD1 (human) RHyWRLDsKCITLFQ S448-p
PRKD1 (mouse) RHYWRLDSKCITLFQ S454
PRKD1 (rat) RHYWRLDSKSITLFQ S454
S466
LFQNDTGSRYyKEIP
0 1
PRKD1 (human) LFQNDTGsRYyKEIP S460-p
PRKD1 (mouse) LFQNDTGSRYyKEIP S466
PRKD1 (rat) LFQNDTGSRYYKEIP S466
Y469-p
NDTGSRYyKEIPLSE
Downstream
7 0
Effects on Modified Protein
  • enzymatic activity, induced
PRKD1 (human) NDTGsRYyKEIPLSE Y463-p
PRKD1 (mouse) NDTGSRYyKEIPLSE Y469-p
PRKD1 (rat) NDTGSRYYKEIPLSE Y469
C479
IPLSEILCLEPAKPS
0 3
PRKD1 (human) IPLSEILsLEPVKTS S473-p
PRKD1 (mouse) IPLSEILCLEPAKPS C479
PRKD1 (rat) IPLSEILCLEPAKPS C479
Y508
TTANVVYYVGENVVN
1 0
PRKD1 (human) TTANVVYyVGENVVN Y502-p
PRKD1 (mouse) TTANVVYYVGENVVN Y508
PRKD1 (rat) TTANVVYYVGENVVN Y508
S554
MPVIPKGSSVGSGSN
0 3
PRKD1 (human) MPVIPKGssVGTGTN S548-p
PRKD1 (mouse) MPVIPKGSSVGSGSN S554
PRKD1 (rat) MPVIPKGSSVGSGTN S554
S555
PVIPKGSSVGSGSNS
0 4
PRKD1 (human) PVIPKGssVGTGTNL S549-p
PRKD1 (mouse) PVIPKGSSVGSGSNS S555
PRKD1 (rat) PVIPKGSSVGSGTNS S555
K618
TGRDVAIKIIDKLRF
0 1
PRKD1 (human) TGRDVAIkIIDKLRF K612-ac
PRKD1 (mouse) TGRDVAIKIIDKLRF K618
PRKD1 (rat) TGRDVAIKIIDKLRF K618
K743-ub
FARIIGEksFRRsVV
0 2
PRKD1 (human) FARIIGEksFRRsVV K737-ub
PRKD1 (mouse) FARIIGEksFRRsVV K743-ub
PRKD1 (rat) FARIIGEKsFRRsVV K743
S744-p
ARIIGEksFRRsVVG
Upstream
Downstream
58 33
PRKD1 (human)
S738-p
PRKD1 (mouse)
S744-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
Kinase, in vitro:
  • PKCE (mouse)
  • PKCH (mouse)
  • PKCZ (mouse)
  • PRKD1 (mouse)
Putative in vivo kinases:
  • PKCA (mouse)
  • PKCE (mouse)
Regulatory protein:
  • EDG4 (human)
  • G-alpha 11 (mouse)
  • G-alpha(q) (mouse)
  • LPAR1 (human)
  • PKCD (mouse)
  • PTPRA (mouse)
Treatment
  • AlF4-
  • antibody
  • autocamtide_inhibitory_peptide
  • BMS-502
  • bombesin
  • BSO
  • endothelin
  • GF109203X
  • Go_6976
  • Go_6983
  • H2O2
  • ionomycin
  • isoproterenol
  • K252a
  • linoleic_acid
  • LPA
  • LY294002
  • MitoQ
  • NAC
  • norepinephrine
  • Pasteurella_multocida_toxin
  • PDGF
  • phorbol_ester
  • PP2
  • PTX
  • Ro31-8220
  • thrombin
  • vasopressin
PRKD1 (human) ARIIGEksFRRsVVG S738-p
PRKD1 (mouse) ARIIGEksFRRsVVG S744-p
PRKD1 (rat) ARIIGEKsFRRsVVG S744-p
S748-p
GEksFRRsVVGtPAy
Upstream
Downstream
56 99
PRKD1 (mouse)
S748-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
Kinase, in vitro:
  • P38D (human)
  • PKCE (mouse)
  • PKCH (mouse)
  • PKCZ (mouse)
  • PRKD1 (mouse)
Putative in vivo kinases:
  • PKCE (mouse)
Regulatory protein:
  • EDG4 (human)
  • G-alpha 11 (mouse)
  • G-alpha(q) (mouse)
  • LPAR1 (human)
  • PKCD (mouse)
  • PTPRA (mouse)
Treatment
  • AlF4-
  • antibody
  • autocamtide_inhibitory_peptide
  • bombesin
  • BSO
  • endothelin
  • GF109203X
  • Go_6976
  • Go_6983
  • H2O2
  • IFN-gamma
  • insulin
  • ionomycin
  • isoproterenol
  • K252a
  • linoleic_acid
  • LPA
  • LY294002
  • MitoQ
  • NAC
  • norepinephrine
  • Pasteurella_multocida_toxin
  • PDGF
  • phorbol_ester
  • thrombin
  • vasopressin
PRKD1 (human) GEksFRRsVVGtPAy S742-p
PRKD1 (mouse) GEksFRRsVVGtPAy S748-p
PRKD1 (rat) GEKsFRRsVVGTPAY S748-p
T752-p
FRRsVVGtPAyLAPE
0 22
PRKD1 (human) FRRsVVGtPAyLAPE T746-p
PRKD1 (mouse) FRRsVVGtPAyLAPE T752-p
PRKD1 (rat) FRRsVVGTPAYLAPE T752
Y755-p
sVVGtPAyLAPEVLR
0 8
PRKD1 (human) sVVGtPAyLAPEVLR Y749-p
PRKD1 (mouse) sVVGtPAyLAPEVLR Y755-p
PRKD1 (rat) sVVGTPAYLAPEVLR Y755
S896
HLISLSASHSDSPEA
0 1
PRKD1 (human) HLINPSAsHsDTPET S890-p
PRKD1 (mouse) HLISLSASHSDSPEA S896
PRKD1 (rat) HLINLSASHGDSPEA S896
S898
ISLSASHSDSPEAEE
0 1
PRKD1 (human) INPSAsHsDTPETEE S892-p
PRKD1 (mouse) ISLSASHSDSPEAEE S898
PRKD1 (rat) INLSASHGDSPEAEE G898
S916-p
KALSERVsIL_____
Upstream
Downstream
43 13
PRKD1 (human)
S910-p
PRKD1 (mouse)
S916-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell motility, altered
  • cytoskeletal reorganization
Kinase, in vitro:
  • PRKD1 (mouse)
  • PRKD2 (mouse)
Putative in vivo kinases:
  • PRKD1 (mouse)
Regulatory protein:
  • EDG4 (human)
  • LPAR1 (human)
  • PTPRA (mouse)
Treatment
  • antibody
  • autocamtide_inhibitory_peptide
  • BMS-502
  • bombesin
  • cytochalasin_D
  • EGF
  • endothelin
  • GF109203X
  • Go_6983
  • H2O2
  • HA-1077
  • insulin
  • isoproterenol
  • K252a
  • KCl
  • LPA
  • NKH_477
  • OVA
  • PD98059
  • PDGF
  • phenylephrine
  • phorbol_ester
  • PP2
  • rapamycin
  • Ro31-8220
  • SB202190
  • thrombin
  • vasopressin
  • wortmannin
PRKD1 (human) KALGERVsIL_____ S910-p
PRKD1 (mouse) KALSERVsIL_____ S916-p
PRKD1 (rat) KALSERVsIL_____ S916-p