Other Species / Isoforms
  PAK1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2
______MSNNGVDIQ
0 3
PAK1 (human) ______MsNNGLDIQ S2-p
PAK1 (mouse) ______MSNNGVDIQ S2
PAK1 (rat) ______MSNNGLDVQ S2
K11
NGVDIQDKPPAPPMR
1 0
PAK1 (human) NGLDIQDkPPAPPMR K11-ub
PAK1 (mouse) NGVDIQDKPPAPPMR K11
PAK1 (rat) NGLDVQDKPPAPPMR K11
T20
PAPPMRNTsTMIGAG
0 1
PAK1 (human) PAPPMRNtsTMIGAG T20-p
PAK1 (mouse) PAPPMRNTsTMIGAG T20
PAK1 (rat) PAPPMRNTsTMIGAG T20
S21-p
APPMRNTsTMIGAGS
Upstream
Downstream
3 10
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • Akt1 (mouse)
Putative in vivo kinases:
  • PAK1 (mouse)
PAK1 (human) APPMRNtsTMIGAGs S21-p
PAK1 (mouse) APPMRNTsTMIGAGS S21-p
PAK1 (rat) APPMRNTsTMIGAGS S21-p
S28
sTMIGAGSKDTGtLN
0 1
PAK1 (human) sTMIGAGskDAGTLN S28-p
PAK1 (mouse) sTMIGAGSKDTGtLN S28
PAK1 (rat) sTMIGAGSKDPGTLN S28
K29
TMIGAGSKDTGtLNH
0 2
PAK1 (human) TMIGAGskDAGTLNH K29-ac
PAK1 (mouse) TMIGAGSKDTGtLNH K29
PAK1 (rat) TMIGAGSKDPGTLNH K29
K29
TMIGAGSKDTGtLNH
1 0
PAK1 (human) TMIGAGskDAGTLNH K29-ub
PAK1 (mouse) TMIGAGSKDTGtLNH K29
PAK1 (rat) TMIGAGSKDPGTLNH K29
T33-p
AGSKDTGtLNHGSKP
0 1
PAK1 (human) AGskDAGTLNHGSkP T33
PAK1 (mouse) AGSKDTGtLNHGSKP T33-p
PAK1 (rat) AGSKDPGTLNHGSKP T33
K39
GtLNHGSKPLPPNPE
1 0
PAK1 (human) GTLNHGSkPLPPNPE K39-ub
PAK1 (mouse) GtLNHGSKPLPPNPE K39
PAK1 (rat) GTLNHGSKPLPPNPE K39
K63
RSILPGDKTNKKREK
0 1
PAK1 (human) RSILPGDkTNKKKEK K63-ac
PAK1 (mouse) RSILPGDKTNKKREK K63
PAK1 (rat) RSILAGDKTNKKKEK K63
T84
LPSDFEHTIHVGFDA
1 0
PAK1 (human) LPSDFEHTIHVGFDA T84
PAK1 (mouse) LPSDFEHTIHVGFDA T84
PAK1 (rat) LPSDFEHtIHVGFDA T84-p
T109-p
QWARLLQtSNITKsE
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, inhibited
Putative in vivo kinases:
  • LKB1 (mouse)
PAK1 (human) QWARLLQtsNITKsE T109-p
PAK1 (mouse) QWARLLQtSNITKsE T109-p
PAK1 (rat) QWARLLQTSNITKSE T109
S110
WARLLQtSNITKsEQ
0 1
PAK1 (human) WARLLQtsNITKsEQ S110-p
PAK1 (mouse) WARLLQtSNITKsEQ S110
PAK1 (rat) WARLLQTSNITKSEQ S110
S115-p
QtSNITKsEQKKNPQ
0 10
PAK1 (human) QtsNITKsEQKKNPQ S115-p
PAK1 (mouse) QtSNITKsEQKKNPQ S115-p
PAK1 (rat) QTSNITKSEQKKNPQ S115
Y131
VLDVLEFYNSKKTSN
0 9
PAK1 (human) VLDVLEFyNsKKtsN Y131-p
PAK1 (mouse) VLDVLEFYNSKKTSN Y131
PAK1 (rat) VLDVLEFYNSKKTSN Y131
S133
DVLEFYNSKKTSNSK
1 3
PAK1 (human) DVLEFyNsKKtsNsQ S133-p
PAK1 (mouse) DVLEFYNSKKTSNSK S133
PAK1 (rat) DVLEFYNSKKTSNSQ S133
T136
EFYNSKKTSNSKKYM
0 5
PAK1 (human) EFyNsKKtsNsQKyM T136-p
PAK1 (mouse) EFYNSKKTSNSKKYM T136
PAK1 (rat) EFYNSKKTSNSQKYM T136
S137
FYNSKKTSNSKKYMs
0 2
PAK1 (human) FyNsKKtsNsQKyMs S137-p
PAK1 (mouse) FYNSKKTSNSKKYMs S137
PAK1 (rat) FYNSKKTSNSQKYMs S137
S139
NSKKTSNSKKYMsFT
0 9
PAK1 (human) NsKKtsNsQKyMsFt S139-p
PAK1 (mouse) NSKKTSNSKKYMsFT S139
PAK1 (rat) NSKKTSNSQKYMsFT S139
Y142
KTSNSKKYMsFTDKS
0 17
PAK1 (human) KtsNsQKyMsFtDks Y142-p
PAK1 (mouse) KTSNSKKYMsFTDKS Y142
PAK1 (rat) KTSNSQKYMsFTDKs Y142
S144-p
SNSKKYMsFTDKSAE
Upstream
22 166
PAK1 (human)
S144-p
PAK1 (mouse)
S144-p
Regulatory protein:
  • PKCH (mouse)
Treatment
  • fMLP
  • UVB
PAK1 (human) sNsQKyMsFtDksAE S144-p
PAK1 (mouse) SNSKKYMsFTDKSAE S144-p
PAK1 (rat) SNSQKYMsFTDKsAE S144-p
T146
SKKYMsFTDKSAEDY
0 15
PAK1 (human) sQKyMsFtDksAEDy T146-p
PAK1 (mouse) SKKYMsFTDKSAEDY T146
PAK1 (rat) SQKYMsFTDKsAEDY T146
K148
KYMsFTDKSAEDYnS
1 0
PAK1 (human) KyMsFtDksAEDyNs K148-ub
PAK1 (mouse) KYMsFTDKSAEDYnS K148
PAK1 (rat) KYMsFTDKsAEDYNS K148
S149
YMsFTDKSAEDYnSS
1 33
PAK1 (human) yMsFtDksAEDyNss S149-p
PAK1 (mouse) YMsFTDKSAEDYnSS S149
PAK1 (rat) YMsFTDKsAEDYNSS S149-p
Y153
TDKSAEDYnSSNtLN
9 22
PAK1 (human) tDksAEDyNssNALN Y153-p
PAK1 (mouse) TDKSAEDYnSSNtLN Y153
PAK1 (rat) TDKsAEDYNSSNTLN Y153
N154-ng
DKSAEDYnSSNtLNV
0 1
PAK1 (human) DksAEDyNssNALNV N154
PAK1 (mouse) DKSAEDYnSSNtLNV N154-ng
PAK1 (rat) DKsAEDYNSSNTLNV N154
S155
KSAEDYnSSNtLNVK
0 7
PAK1 (human) ksAEDyNssNALNVK S155-p
PAK1 (mouse) KSAEDYnSSNtLNVK S155
PAK1 (rat) KsAEDYNSSNTLNVK S155
S156
SAEDYnSSNtLNVKT
0 2
PAK1 (human) sAEDyNssNALNVKA S156-p
PAK1 (mouse) SAEDYnSSNtLNVKT S156
PAK1 (rat) sAEDYNSSNTLNVKT S156
T158-p
EDYnSSNtLNVKTVS
0 1
PAK1 (human) EDyNssNALNVKAVS A158
PAK1 (mouse) EDYnSSNtLNVKTVS T158-p
PAK1 (rat) EDYNSSNTLNVKTVS T158
S174-p
TPAVPPVsEDDEDDD
1 29
PAK1 (human) TPAVPPVsEDEDDDD S174-p
PAK1 (mouse) TPAVPPVsEDDEDDD S174-p
PAK1 (rat) TPAVPPVsEDEDDDD S174-p
T185-p
EDDDDDAtPPPVIAP
0 9
PAK1 (human) DDDDDDAtPPPVIAP T185-p
PAK1 (mouse) EDDDDDAtPPPVIAP T185-p
PAK1 (rat) EDDDDDATPPPVIAP T184
T197
IAPRPEHTKsVYTRs
0 1
PAK1 (human) IAPRPEHtKsVyTRs T197-p
PAK1 (mouse) IAPRPEHTKsVYTRs T197
PAK1 (rat) IAPRPEHTKsVYTRs T196
S199-p
PRPEHTKsVYTRsVI
Upstream
15 0
PAK1 (human)
S199-p
PAK1 (mouse)
S199-p
Regulatory protein:
  • FMR1 (mouse)
  • IFITM3 (human)
  • IFITM3 (rat)
  • NPM-ALK (human)
Treatment
  • fMLP
  • LY294002
  • SU6656
PAK1 (human) PRPEHtKsVyTRsVI S199-p
PAK1 (mouse) PRPEHTKsVYTRsVI S199-p
PAK1 (rat) PRPEHTKsVYTRsVI S198-p
Y201
PEHTKsVYTRsVIEP
9 0
PAK1 (human) PEHtKsVyTRsVIEP Y201-p
PAK1 (mouse) PEHTKsVYTRsVIEP Y201
PAK1 (rat) PEHTKsVYTRsVIEP Y200
S204-p
TKsVYTRsVIEPLPV
Upstream
16 16
PAK1 (human)
S204-p
PAK1 (mouse)
S204-p
Regulatory protein:
  • IFITM3 (human)
  • IFITM3 (rat)
  • NPM-ALK (human)
Treatment
  • bacterial infection
  • fMLP
  • LY294002
  • SU6656
PAK1 (human) tKsVyTRsVIEPLPV S204-p
PAK1 (mouse) TKsVYTRsVIEPLPV S204-p
PAK1 (rat) TKsVYTRsVIEPLPV S203-p
T212-p
VIEPLPVtPtRDVAt
Upstream
Downstream
16 41
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell motility, altered
  • cytoskeletal reorganization
Kinase, in vitro:
  • CDK1 (human)
  • CDK1 (mouse)
  • CDK5 (mouse)
Putative in vivo kinases:
  • CDK5 (mouse)
Regulatory protein:
  • CDK5R1 (mouse)
  • PMP22 (mouse)
  • RAC1 (mouse)
Treatment
  • IL-33
  • mutation
  • PF3758309
  • UVB
PAK1 (human) VIEPLPVtPtRDVAt T212-p
PAK1 (mouse) VIEPLPVtPtRDVAt T212-p
PAK1 (rat) VIEPLPVtPTRDVAT T211-p
T214-p
EPLPVtPtRDVAtsP
0 6
PAK1 (human) EPLPVtPtRDVAtsP T214-p
PAK1 (mouse) EPLPVtPtRDVAtsP T214-p
PAK1 (rat) EPLPVtPTRDVATsP T213
T219-p
tPtRDVAtsPIsPtE
0 5
PAK1 (human) tPtRDVAtsPIsPtE T219-p
PAK1 (mouse) tPtRDVAtsPIsPtE T219-p
PAK1 (rat) tPTRDVATsPIsPTE T218
S220-p
PtRDVAtsPIsPtEN
0 14
PAK1 (human) PtRDVAtsPIsPtEN S220-p
PAK1 (mouse) PtRDVAtsPIsPtEN S220-p
PAK1 (rat) PTRDVATsPIsPTEN S219-p
S223-p
DVAtsPIsPtENNtt
Upstream
2 34
Treatment
  • long-term_potentiation
PAK1 (human) DVAtsPIsPtENNtt S223-p
PAK1 (mouse) DVAtsPIsPtENNtt S223-p
PAK1 (rat) DVATsPIsPTENNTt S222-p
T225-p
AtsPIsPtENNttPP
0 17
PAK1 (human) AtsPIsPtENNttPP T225-p
PAK1 (mouse) AtsPIsPtENNttPP T225-p
PAK1 (rat) ATsPIsPTENNTtPP T224
T229-p
IsPtENNttPPDALT
0 11
PAK1 (human) IsPtENNttPPDALt T229-p
PAK1 (mouse) IsPtENNttPPDALT T229-p
PAK1 (rat) IsPTENNTtPPDALT T228
T230-p
sPtENNttPPDALTR
Upstream
0 46
Treatment
  • BMP2
PAK1 (human) sPtENNttPPDALtR T230-p
PAK1 (mouse) sPtENNttPPDALTR T230-p
PAK1 (rat) sPTENNTtPPDALTR T229-p
T236
ttPPDALTRNTEKQK
0 2
PAK1 (human) ttPPDALtRNTEKQK T236-p
PAK1 (mouse) ttPPDALTRNTEKQK T236
PAK1 (rat) TtPPDALTRNTEKQK T235
S249-p
QKKKPKMsDEEILEK
0 3
PAK1 (human) QKKKPKMsDEEILEk S249-p
PAK1 (mouse) QKKKPKMsDEEILEK S249-p
PAK1 (rat) QKKKPKMSDEEILEK S248
K256
sDEEILEKLRsIVsV
0 1
PAK1 (human) sDEEILEkLRsIVsV K256-ac
PAK1 (mouse) sDEEILEKLRsIVsV K256
PAK1 (rat) SDEEILEKLRSIVSV K255
K256
sDEEILEKLRsIVsV
0 2
PAK1 (human) sDEEILEkLRsIVsV K256-ub
PAK1 (mouse) sDEEILEKLRsIVsV K256
PAK1 (rat) SDEEILEKLRSIVSV K255
K256
sDEEILEKLRsIVsV
0 1
PAK1 (human) sDEEILEkLRsIVsV K256-sm
PAK1 (mouse) sDEEILEKLRsIVsV K256
PAK1 (rat) SDEEILEKLRSIVSV K255
S259-p
EILEKLRsIVsVGDP
0 3
PAK1 (human) EILEkLRsIVsVGDP S259-p
PAK1 (mouse) EILEKLRsIVsVGDP S259-p
PAK1 (rat) EILEKLRSIVSVGDP S258
S262-p
EKLRsIVsVGDPKKK
0 2
PAK1 (human) EkLRsIVsVGDPKKK S262-p
PAK1 (mouse) EKLRsIVsVGDPKKK S262-p
PAK1 (rat) EKLRSIVSVGDPKKK S261
Y285
QGASGTVYTAMDVAT
9 2
PAK1 (human) QGASGTVyTAMDVAT Y285-p
PAK1 (mouse) QGASGTVYTAMDVAT Y285
PAK1 (rat) QGASGTVYTAMDVAT Y284
K391-ub
QVIHRDIkSDNILLG
0 2
PAK1 (human) QVIHRDIkSDNILLG K391-ub
PAK1 (mouse) QVIHRDIkSDNILLG K391-ub
PAK1 (rat) QVIHRDIKSDNILLG K390
T415
FGFCAQITPEQSKRs
0 2
PAK1 (human) FGFCAQItPEQSkRs T415-p
PAK1 (mouse) FGFCAQITPEQSKRs T415
PAK1 (rat) FGFCAQITPEQSKRs T414
K420
QITPEQSKRstMVGt
0 1
PAK1 (human) QItPEQSkRstMVGt K420-ac
PAK1 (mouse) QITPEQSKRstMVGt K420
PAK1 (rat) QITPEQSKRstMVGT K419
K420
QITPEQSKRstMVGt
0 13
PAK1 (human) QItPEQSkRstMVGt K420-ub
PAK1 (mouse) QITPEQSKRstMVGt K420
PAK1 (rat) QITPEQSKRstMVGT K419
S422-p
TPEQSKRstMVGtPY
0 5
PAK1 (human) tPEQSkRstMVGtPY S422-p
PAK1 (mouse) TPEQSKRstMVGtPY S422-p
PAK1 (rat) TPEQSKRstMVGTPY S421-p
T423-p
PEQSKRstMVGtPYW
Upstream
Downstream
37 14
PAK1 (human)
T423-p
PAK1 (mouse)
T423-p
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • fMLP
  • IFN-gamma
  • SCF
  • virus infection
PAK1 (human) PEQSkRstMVGtPYW T423-p
PAK1 (mouse) PEQSKRstMVGtPYW T423-p
PAK1 (rat) PEQSKRstMVGTPYW T422-p
T427-p
KRstMVGtPYWMAPE
0 4
PAK1 (human) kRstMVGtPYWMAPE T427-p
PAK1 (mouse) KRstMVGtPYWMAPE T427-p
PAK1 (rat) KRstMVGTPYWMAPE T426
Y474
ENPLRALYLIATNGT
0 10
PAK1 (human) ENPLRALyLIATNGT Y474-p
PAK1 (mouse) ENPLRALYLIATNGT Y474
PAK1 (rat) ENPLRALYLIATNGT Y473
S491
LQNPEKLSAIFRDFL
0 1
PAK1 (human) LQNPEKLsAIFRDFL S491-p
PAK1 (mouse) LQNPEKLSAIFRDFL S491
PAK1 (rat) LQNPEKLSAIFRDFL S490
K513
VEKRGSAKELLQHQF
0 1
PAK1 (human) VEKRGSAkELLQHQF K513-ac
PAK1 (mouse) VEKRGSAKELLQHQF K513
PAK1 (rat) VEKRGSAKELLQHQF K512
S528
LKIAKPLSSLTPLMH
0 1
PAK1 (human) LKIAKPLssLtPLIA S528-p
PAK1 (mouse) LKIAKPLSSLTPLMH S528
PAK1 (rat) LKIAKPLSSLTPLIA S527
S529
KIAKPLSSLTPLMHA
0 1
PAK1 (human) KIAKPLssLtPLIAA S529-p
PAK1 (mouse) KIAKPLSSLTPLMHA S529
PAK1 (rat) KIAKPLSSLTPLIAA S528
T531
AKPLSSLTPLMHAAK
0 1
PAK1 (human) AKPLssLtPLIAAAK T531-p
PAK1 (mouse) AKPLSSLTPLMHAAK T531
PAK1 (rat) AKPLSSLTPLIAAAK T530