Other Species / Isoforms
  eNOS (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K5
___MGNLKSVGQEPG
0 1
eNOS (human) ___MGNLkSVAQEPG K5-m1
eNOS (mouse) ___MGNLKSVGQEPG K5
eNOS (rat) ___MGNLKSVGQEPG K5
eNOS (rabbit) ___MGNLKSVGQEPG K5
eNOS (pig) ___MGNLKSVAQEPG K5
eNOS (cow) ___MGNLKSVGQEPG K5
S33
CGKQGPASPAPEPSQ
0 1
eNOS (human) CGKQGPAtPAPEPSR T33-p
eNOS (mouse) CGKQGPASPAPEPSQ S33
eNOS (rat) CGKQGPASPAPEPSQ S33
eNOS (rabbit) CGKQGPASPAPEPSR S33
eNOS (pig) CGKQGPASPAPEASQ S33
eNOS (cow) CGKQGPASPAPEPSR S33
T48-p
APAPPsPtRPAPDHs
0 2
eNOS (human) gap -
eNOS (mouse) APAPPsPtRPAPDHs T48-p
eNOS (rat) APVPPSPTRPAPDHS T48
eNOS (rabbit) APASPPPTPPAPDHS T48
eNOS (pig) gap -
eNOS (cow) SRAPAPAtPHAPDHS T46-p
S46-p
SQAPAPPsPtRPAPD
0 1
eNOS (human) gap -
eNOS (mouse) SQAPAPPsPtRPAPD S46-p
eNOS (rat) under review -
eNOS (rabbit) under review -
eNOS (pig) gap -
eNOS (cow) under review -
S55-p
tRPAPDHsPPLtRPP
0 3
eNOS (human) LPPAPEHsPPSSPLT S53-p
eNOS (mouse) tRPAPDHsPPLtRPP S55-p
eNOS (rat) TRPAPDHSPPLTRPP S55
eNOS (rabbit) TPPAPDHSPKPSSNS S55
eNOS (pig) PAPAPDHSPAPNSPP S53
eNOS (cow) tPHAPDHSPAPNsPT S53
-
gap
0 1
eNOS (human) gap -
eNOS (mouse) gap -
eNOS (rat) gap -
eNOS (rabbit) SPKPSSNSPPLTRPP S62
eNOS (pig) DHSPAPNSPPLTRPP S58
eNOS (cow) DHSPAPNsPTLTRPP S58-p
T59-p
PDHsPPLtRPPDGPR
0 1
eNOS (human) sPPSSPLTQPPEGPK T60
eNOS (mouse) PDHsPPLtRPPDGPR T59-p
eNOS (rat) PDHSPPLTRPPDGPK T59
eNOS (rabbit) SSNSPPLTRPPEGPK T66
eNOS (pig) APNSPPLTRPPEGPK T62
eNOS (cow) APNsPTLTRPPEGPK T62
Y80-p
WEVGSITyDTLSAQA
5 1
eNOS (human) WEVGSITyDTLSAQA Y81-p
eNOS (mouse) WEVGSITyDTLSAQA Y80-p
eNOS (rat) WEVGSITyDTLSAQA Y80-p
eNOS (rabbit) WEVGSITYDTLSAQA Y87
eNOS (pig) WEVGSITYDTLCAQS Y83
eNOS (cow) WELGSITyDTLCAQS Y83-p
S101
TSRRCLGSLVFPRKL
0 2
eNOS (human) TPRRCLGsLVFPRKL S102-p
eNOS (mouse) TSRRCLGSLVFPRKL S101
eNOS (rat) TPRRCLGSLVFPRKL S101
eNOS (rabbit) TQRRCLGSLVFPRKL S108
eNOS (pig) TPRRCLGSLVFPRKL S104
eNOS (cow) TPRCCLGSLVLPRKL S104
T113
RKLQSRPTQGPSPTE
18 4
eNOS (human)
S114-p
eNOS (cow)
S116-p
eNOS (human) RKLQGRPsPGPPAPE S114-p
eNOS (mouse) RKLQSRPTQGPSPTE T113
eNOS (rat) RKLQSRPTQGPsPTE T113
eNOS (rabbit) RKLQSRPTQGAPPPE T120
eNOS (pig) RKLQSRPSQGPPPTE S116
eNOS (cow) RKLQTRPsPGPPPAE S116-p
S117
SRPTQGPSPTEQLLG
1 0
eNOS (human) GRPsPGPPAPEQLLS P118
eNOS (mouse) SRPTQGPSPTEQLLG S117
eNOS (rat) SRPTQGPsPTEQLLG S117-p
eNOS (rabbit) SRPTQGAPPPEQLLV P124
eNOS (pig) SRPSQGPPPTEQLLS P120
eNOS (cow) TRPsPGPPPAEQLLS P120
Y209
TAQEMFTYICNHIKY
0 1
eNOS (human) SAQEMFTyICNHIKY Y210-p
eNOS (mouse) TAQEMFTYICNHIKY Y209
eNOS (rat) TAQEMFTYICNHIKY Y209
eNOS (rabbit) SAQEMFTYICNHIKY Y216
eNOS (pig) SAQEMFTYICNHIKY Y212
eNOS (cow) SAQEMFTYICNHIKY Y212
S259
GYRQQDGSVRGDPAN
0 1
eNOS (human) GYRQQDGsVRGDPAN S260-p
eNOS (mouse) GYRQQDGSVRGDPAN S259
eNOS (rat) GYRQQDGSVRGDPAN S259
eNOS (rabbit) GYRQQDGSVRGDPAN S266
eNOS (pig) GYRQQDGSVRGDPAN S262
eNOS (cow) GYRQQDGSVRGDPAN S262
S482-p
QPDPWKGsAAKGAGI
Upstream
0 1
Treatment
  • insulin
  • LY294002
eNOS (human) QPDPWKGSAAKGTGI S483
eNOS (mouse) QPDPWKGsAAKGAGI S482-p
eNOS (rat) QPDPWKGSAAKGTGI S482
eNOS (rabbit) QPDPWKGSGAKGTGI S489
eNOS (pig) QPDPWKGSAAKGTGI S485
eNOS (cow) QPDPWKGSATKGAGI S485
K493
GAGITRKKtFKEVAN
1 0
eNOS (human) GTGITRKKtFKEVAN K494
eNOS (mouse) GAGITRKKtFKEVAN K493
eNOS (rat) GTGITRKKtFKEVAN K493
eNOS (rabbit) GTGITRKKTFKEVAN K500
eNOS (pig) GTGIARKKtFKEVAN K496
eNOS (cow) GAGITRKktFKEVAN K496-ac
T494-p
AGITRKKtFKEVANA
Upstream
59 3
eNOS (human)
T495-p
eNOS (mouse)
T494-p
Regulatory protein:
  • AMPKA2 (mouse)
  • APOE (mouse)
  • FKBP12 (mouse)
  • FKBP14 (mouse)
Treatment
  • ACh
  • FGF2
  • Go_6976
  • ischemia/reperfusion
  • metformin
  • PGE2
  • rapamycin
  • ryanodine
eNOS (human) TGITRKKtFKEVANA T495-p
eNOS (mouse) AGITRKKtFKEVANA T494-p
eNOS (rat) TGITRKKtFKEVANA T494-p
eNOS (rabbit) TGITRKKTFKEVANA T501
eNOS (pig) TGIARKKtFKEVANA T497-p
eNOS (cow) AGITRKktFKEVANA T497-p
K503
KEVANAVKISASLMG
1 0
eNOS (human) KEVANAVKISAsLMG K504
eNOS (mouse) KEVANAVKISASLMG K503
eNOS (rat) KEVANAVKISASLMG K503
eNOS (rabbit) KEVANAVKISASLMG K510
eNOS (pig) KEVANAVKISASLMG K506
eNOS (cow) KEVANAVkISASLMG K506-ac
S507
NAVKISASLMGTVMA
0 2
eNOS (human) NAVKISAsLMGtVMA S508-p
eNOS (mouse) NAVKISASLMGTVMA S507
eNOS (rat) NAVKISASLMGTVMA S507
eNOS (rabbit) NAVKISASLMGTVMA S514
eNOS (pig) NAVKISASLMGTVMA S510
eNOS (cow) NAVkISASLMGTLMA S510
T511
ISASLMGTVMAKRVK
0 2
eNOS (human) ISAsLMGtVMAKRVK T512-p
eNOS (mouse) ISASLMGTVMAKRVK T511
eNOS (rat) ISASLMGTVMAKRVK T511
eNOS (rabbit) ISASLMGTVMAKRVK T518
eNOS (pig) ISASLMGTVMAKRVK T514
eNOS (cow) ISASLMGTLMAKRVK T514
S599
MSGPYNSSPRPEQHK
0 1
eNOS (human) MSGPYNSSPRPEQHK S600
eNOS (mouse) MSGPYNSSPRPEQHK S599
eNOS (rat) MSGPYNSSPRPEQHK S599
eNOS (rabbit) MSGPYNSSPRPEQHK S606
eNOS (pig) MSGPYNGSPRPEQHR S602
eNOS (cow) MSGPYNSsPRPEQHK S602-p
S614-p
SYKIRFNsVSCSDPL
Upstream
11 5
Treatment
  • insulin
eNOS (human) SYKIRFNsISCSDPL S615-p
eNOS (mouse) SYKIRFNsVSCSDPL S614-p
eNOS (rat) SYKIRFNsVSCSDPL S614-p
eNOS (rabbit) SYKIRFNSVSCSDPL S621
eNOS (pig) SYKIRFNSVSCSDPL S617
eNOS (cow) SYKIRFNsVSCSDPL S617-p
S632-p
WRRKRKEsSNtDSAG
Upstream
23 19
Regulatory protein:
  • AMPKA2 (mouse)
Treatment
  • angiotensin_2
  • blood pressure
  • H-89
  • icatibant
  • insulin
  • KT5720
  • LY294002
  • PD123319
  • wortmannin
eNOS (human) WRRKRKEssNtDsAG S633-p
eNOS (mouse) WRRKRKEsSNtDSAG S632-p
eNOS (rat) WRRKRKEsSNTDSAG S632-p
eNOS (rabbit) WRRKRKESSNTDSAG S639
eNOS (pig) WRRKRKESSNTDSAG S635
eNOS (cow) WRRKRKEsSNTDSAG S635-p
S633
RRKRKEsSNtDSAGA
0 1
eNOS (human) RRKRKEssNtDsAGA S634-p
eNOS (mouse) RRKRKEsSNtDSAGA S633
eNOS (rat) RRKRKEsSNTDSAGA S633
eNOS (rabbit) RRKRKESSNTDSAGA S640
eNOS (pig) RRKRKESSNTDSAGA S636
eNOS (cow) RRKRKEsSNTDSAGA S636
T635-p
KRKEsSNtDSAGALG
Upstream
0 2
Treatment
  • insulin
eNOS (human) KRKEssNtDsAGALG T636-p
eNOS (mouse) KRKEsSNtDSAGALG T635-p
eNOS (rat) KRKEsSNTDSAGALG T635
eNOS (rabbit) KRKESSNTDSAGALG T642
eNOS (pig) KRKESSNTDSAGALG T638
eNOS (cow) KRKEsSNTDSAGALG T638
S637
KEsSNtDSAGALGTL
0 1
eNOS (human) KEssNtDsAGALGTL S638-p
eNOS (mouse) KEsSNtDSAGALGTL S637
eNOS (rat) KEsSNTDSAGALGTL S637
eNOS (rabbit) KESSNTDSAGALGTL S644
eNOS (pig) KESSNTDSAGALGTL S640
eNOS (cow) KEsSNTDSAGALGTL S640
Y656-p
FGLGSRAyPHFCAFA
Upstream
Downstream
6 1
Effects on Modified Protein
  • molecular association, regulation
Putative in vivo kinases:
  • Pyk2 (human)
Treatment
  • angiotensin_2
  • H2O2
  • siRNA
  • telmisartan
eNOS (human) FGLGSRAyPHFCAFA Y657-p
eNOS (mouse) FGLGSRAyPHFCAFA Y656-p
eNOS (rat) FGLGSRAyPHFCAFA Y656-p
eNOS (rabbit) FGLGSRAYPHFCAFA Y663
eNOS (pig) FGLGSRAyPHFCAFA Y659-p
eNOS (cow) FGLGSRAYPHFCAFA Y659
S737
KRQRYRLSTQAESLQ
0 2
eNOS (human) KRQRYRLsAQAEGLQ S738-p
eNOS (mouse) KRQRYRLSTQAESLQ S737
eNOS (rat) KRQRYRLSTQAESLQ S737
eNOS (rabbit) KRQRYRLSTQTEGLQ S744
eNOS (pig) KRQRYRLSAQAEGLQ S740
eNOS (cow) KRQRYRLSTQAEGLQ S740
K772
VENLQSSKSTRATIL
0 1
eNOS (human) VENLQSSkSTRATIL K773-ub
eNOS (mouse) VENLQSSKSTRATIL K772
eNOS (rat) VENLQSSKSTRATIL K772
eNOS (rabbit) VENLQSSKSTRATIL K779
eNOS (pig) VENLQSSKSTRATIL K775
eNOS (cow) VENLQSSKSTRATIL K775
K833
VAVEQLEKGSPGGPP
0 2
eNOS (human) VAVEQLEkGsPGGPP K834-ub
eNOS (mouse) VAVEQLEKGSPGGPP K833
eNOS (rat) VAVEQLEKGSPGGPP K833
eNOS (rabbit) VAVEQLEKGSPGGPP K840
eNOS (pig) VAVEQLEKGSPGGPP K836
eNOS (cow) VAVEQLEKGSPGGPP K836
S835
VEQLEKGSPGGPPPG
0 1
eNOS (human) VEQLEkGsPGGPPPG S836-p
eNOS (mouse) VEQLEKGSPGGPPPG S835
eNOS (rat) VEQLEKGSPGGPPPG S835
eNOS (rabbit) VEQLEKGSPGGPPPS S842
eNOS (pig) VEQLEKGSPGGPPPS S838
eNOS (cow) VEQLEKGSPGGPPPS S838
T853
DPRLPPCTLRQALTY
0 1
eNOS (human) DPRLPPCtLRQALTF T854-p
eNOS (mouse) DPRLPPCTLRQALTY T853
eNOS (rat) DPRLPPCTLRQALTY T853
eNOS (rabbit) DPRLPPCSLRQALTF S860
eNOS (pig) DPRLPPCTLRQALTF T856
eNOS (cow) DPRLPPCTLRQALTF T856
K903
PRRYEEWKWFSCPTL
0 1
eNOS (human) PRRYEEWkWFRCPTL K904-ub
eNOS (mouse) PRRYEEWKWFSCPTL K903
eNOS (rat) PRRYEEWKWFRCPTL K903
eNOS (rabbit) PRRYEEWKWFRCPTL K910
eNOS (pig) PRRYEEWKWFRCPTL K906
eNOS (cow) PRRYEEWKWFRCPTL K906
K1034
RLHDIEIKGLQPAPM
0 1
eNOS (human) RLHDIESkGLQPTPM K1035-ub
eNOS (mouse) RLHDIEIKGLQPAPM K1034
eNOS (rat) RLHDIEIKGLQPAPM K1034
eNOS (rabbit) RLHDIESKGLQPAPL K1041
eNOS (pig) RLHDIESKGLQPAPM K1037
eNOS (cow) RLHDIESKGLQPAPM K1037
K1084
SRDPGSPKTYVQDLL
0 3
eNOS (human) SREPDNPkTYVQDIL K1085-ub
eNOS (mouse) SRDPGSPKTYVQDLL K1084
eNOS (rat) SRDPGSPKTYVQDLL K1084
eNOS (rabbit) SREPDSPKTYVQDIL K1091
eNOS (pig) SREPDSPKTYVQDIL K1087
eNOS (cow) SREPDSPKTYVQDIL K1087
K1084
SRDPGSPKTYVQDLL
0 1
eNOS (human) SREPDNPKTYVQDIL K1085
eNOS (mouse) SRDPGSPKTYVQDLL K1084
eNOS (rat) SRDPGSPkTYVQDLL K1084-ac
eNOS (rabbit) SREPDSPKTYVQDIL K1091
eNOS (pig) SREPDSPKTYVQDIL K1087
eNOS (cow) SREPDSPKTYVQDIL K1087
T1093
YVQDLLRTELAAEVH
0 1
eNOS (human) YVQDILRtELAAEVH T1094-p
eNOS (mouse) YVQDLLRTELAAEVH T1093
eNOS (rat) YVQDLLRTELAAEVH T1093
eNOS (rabbit) YVQDILRTELASEVH T1100
eNOS (pig) YVQDILRTELAAEVH T1096
eNOS (cow) YVQDILRTELAAEVH T1096
T1174-p
EVTSRIRtQsFsLQE
Upstream
2 19
Treatment
  • insulin
  • MK-2206
eNOS (human) EVTSRIRtQsFsLQE T1175-p
eNOS (mouse) EVTSRIRtQsFsLQE T1174-p
eNOS (rat) EVTSRIRtQsFsLQE T1174-p
eNOS (rabbit) EVTSRIRTQsFSLQE T1181
eNOS (pig) EVTSRIRtQsFSLQE T1177-p
eNOS (cow) EVTSRIRtQsFsLQE T1177-p
S1176-p
TSRIRtQsFsLQERQ
Upstream
Downstream
159 25
eNOS (human)
S1177-p
eNOS (mouse)
S1176-p
eNOS (rat)
S1176-p
eNOS (cow)
S1179-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • signaling pathway regulation
Putative in vivo kinases:
  • CAMK2A (human)
  • PKACA (human)
Regulatory protein:
  • AMPKA2 (mouse)
  • APOE (mouse)
  • BVR (human)
  • PKCA (mouse)
  • PPP2CA (mouse)
Treatment
  • 8-(3-chlorostyryl) caffeine
  • acadesine
  • ACh
  • Akt_inhibitor_IV
  • alloxazine
  • angiotensin_2
  • atorvastatin
  • BAPTA-AM
  • blood pressure
  • DPCPX
  • FGF2
  • geldanamycin
  • H-89
  • hypertension
  • icatibant
  • IL-6
  • insulin
  • ischemia
  • ischemia/reperfusion
  • JNK_inhibitor_I
  • KT5720
  • LY294002
  • metformin
  • MK-2206
  • MK801
  • mPKI
  • MRS-1523
  • nicardipine
  • oleic_acid
  • palmitate
  • PD123319
  • PD98059
  • PGE2
  • SPT
  • STO-609
  • Theophylline
  • U0126
  • uPA
  • VEGF
  • wortmannin
eNOS (human) TSRIRtQsFsLQERQ S1177-p
eNOS (mouse) TSRIRtQsFsLQERQ S1176-p
eNOS (rat) TSRIRtQsFsLQERQ S1176-p
eNOS (rabbit) TSRIRTQsFSLQERQ S1183-p
eNOS (pig) TSRIRtQsFSLQERH S1179-p
eNOS (cow) TSRIRtQsFsLQERH S1179-p
S1176
TSRIRtQSFsLQERQ
2 0
eNOS (human) TSRIRtQsFsLQERQ S1177-gl
eNOS (mouse) TSRIRtQSFsLQERQ S1176
eNOS (rat) TSRIRtQsFsLQERQ S1176-gl
eNOS (rabbit) TSRIRTQSFSLQERQ S1183
eNOS (pig) TSRIRtQSFSLQERH S1179
eNOS (cow) TSRIRtQSFsLQERH S1179
S1178-p
RIRtQsFsLQERQLR
Upstream
Downstream
8 8
Effects on Modified Protein
  • intracellular localization
Regulatory protein:
  • ICAM1 (mouse)
Treatment
  • CRP
  • insulin
eNOS (human) RIRtQsFsLQERQLR S1179-p
eNOS (mouse) RIRtQsFsLQERQLR S1178-p
eNOS (rat) RIRtQsFsLQERQLR S1178-p
eNOS (rabbit) RIRTQsFSLQERQLR S1185
eNOS (pig) RIRtQsFSLQERHLR S1181
eNOS (cow) RIRtQsFsLQERHLR S1181-p